Dennis A Wigle, MD, PhD

  • 8672 Citations
  • 38 Scopus h-Index
1991 …2019

Research output per year

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Research Output

  • 8672 Citations
  • 38 Scopus h-Index
  • 185 Article
  • 2 Review article
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Article
2019

Comparison of Laparoscopic Versus Open Surgical Management of Morgagni Hernia

Young, M. C., Saddoughi, S. A., Aho, J. M., Harmsen, W. S., Allen, M. S., Blackmon, S. H., Cassivi, S. D., Nichols, F. C., Shen, K. R. & Wigle, D. A., Jan 1 2019, In : Annals of Thoracic Surgery. 107, 1, p. 257-261 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Immune Cell Infiltration May Be a Key Determinant of Long-Term Survival in Small Cell Lung Cancer

Muppa, P., Parrilha Terra, S. B. S., Sharma, A., Mansfield, A., Aubry, M. C., Bhinge, K., Asiedu, M. K., De Andrade, M., Janaki, N., Murphy, S. J., Nasir, A., Van Keulen, V., Vasmatzis, G., Wigle, D. A., Yang, P., Yi, E. S., Peikert, T. D. & Kosari, F., Jul 1 2019, In : Journal of Thoracic Oncology. 14, 7, p. 1286-1295 10 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Targeted Derivation of Organotypic Glucose- and GLP-1-Responsive β Cells Prior to Transplantation into Diabetic Recipients

Zhu, Y., Tonne, J. M., Liu, Q., Schreiber, C. A., Zhou, Z., Rakshit, K., Matveyenko, A. V., Terzic, A., Wigle, D. A., Kudva, Y. C. & Ikeda, Y., Aug 13 2019, In : Stem Cell Reports. 13, 2, p. 307-321 15 p.

Research output: Contribution to journalArticle

Open Access

Using Genomics to Differentiate Multiple Primaries From Metastatic Lung Cancer

Murphy, S. J., Harris, F. R., Kosari, F., Barreto Siqueira Parrilha Terra, S., Nasir, A., Johnson, S. H., Serla, V., Smadbeck, J., Halling, G. C., Karagouga, G., Sukov, W. R., Leventakos, K., Yang, P., Peikert, T. D., Mansfield, A., Wigle, D. A., Yi, E. S., Kipp, B. R., Vasmatzis, G. & Aubry, M. C., Jan 1 2019, In : Journal of Thoracic Oncology.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2018

A comparison between Belsey Mark IV and laparoscopic Nissen fundoplication in patients with large paraesophageal hernia

Laan, D. V., Agzarian, J., Harmsen, W. S., Shen, K. R., Blackmon, S. H., Nichols, F. C., Cassivi, S. D., Wigle, D. A. & Allen, M. S., Jan 1 2018, (Accepted/In press) In : Journal of Thoracic and Cardiovascular Surgery.

Research output: Contribution to journalArticle

1 Scopus citations

Analysis of Patients Discharged From the Hospital With a Chest Tube in Place

Reinersman, J. M., Allen, M. S., Blackmon, S. H., Cassivi, S. D., Nichols, F. C., Wigle, D. A. & Shen, K. R., Jan 1 2018, (Accepted/In press) In : Annals of Thoracic Surgery.

Research output: Contribution to journalArticle

Can MRI contribute to pulmonary nodule analysis?

Koo, C. W., Lu, A., Takahashi, E. A., Simmons, C. L., Geske, J. R., Wigle, D. A. & Peikert, T. D., Jan 1 2018, (Accepted/In press) In : Journal of Magnetic Resonance Imaging.

Research output: Contribution to journalArticle

Chylothorax as a Risk Factor for Thrombosis in Adults: A Proof-of-Concept Study

Hoskote, S. S., Yadav, H., Jagtap, P., Wigle, D. A. & Daniels, C. E., Apr 1 2018, In : Annals of Thoracic Surgery. 105, 4, p. 1065-1070 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Comparison of Risk Stratification Models to Predict Recurrence and Survival in Pleuropulmonary Solitary Fibrous Tumor

Reisenauer, J. S., Mneimneh, W., Jenkins, S., Mansfield, A., Aubry, M. C., Fritchie, K. J., Allen, M. S., Blackmon, S. H., Cassivi, S. D., Nichols, F. C., Wigle, D. A., Shen, K. R. & Boland, J. M., Jan 1 2018, (Accepted/In press) In : Journal of Thoracic Oncology.

Research output: Contribution to journalArticle

6 Scopus citations

Extracellular matrix fistula plug for repair of bronchopleural fistula

Sakata, K. K., Reisenauer, J. S., Kern, R. M., Midthun, D. E., Utz, J. P., Blackmon, S. H., Mullon, J. J. & Wigle, D. A., Jan 1 2018, In : Respiratory Medicine Case Reports. 25, p. 207-210 4 p.

Research output: Contribution to journalArticle

Long-term regeneration and remodeling of the pig esophagus after circumferential resection using a retrievable synthetic scaffold carrying autologous cells

La Francesca, S., Aho, J. M., Barron, M. R., Blanco, E. W., Soliman, S., Kalenjian, L., Hanson, A. D., Todorova, E., Marsh, M., Burnette, K. L., DerSimonian, H., Odze, R. D. & Wigle, D. A., Dec 1 2018, In : Scientific Reports. 8, 1, 4123.

Research output: Contribution to journalArticle

14 Scopus citations

Nomogram prediction of overall survival for patients with non-small-cell lung cancer incorporating pretreatment peripheral blood markers

Xie, D., Allen, M. S., Marks, R. S., Jiang, G., Sun, Z. D., Nichols, F., Zhang, M., Chen, C., Aubry, M. C., Jatoi, A., Garces, Y. I., Mansfield, A., Wigle, D. A., Molina, J. R., Deschamps, C. & Yang, P., Jun 1 2018, In : European Journal of Cardio-thoracic Surgery. 53, 6, p. 1214-1222 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Pathways impacted by genomic alterations in pulmonary carcinoid tumors

Asiedu, M. K., Thomas, C. F., Dong, J., Schulte, S. C., Khadka, P., Sun, Z. D., Kosari, F., Jen, J., Molina, J. R., Vasmatzis, G., Kuang, R., Aubry, M. C., Yang, P. & Wigle, D. A., Apr 1 2018, In : Clinical Cancer Research. 24, 7, p. 1691-1704 14 p.

Research output: Contribution to journalArticle

12 Scopus citations

Perioperative mortality and morbidity after sublobar versus lobar resection for early-stage non-small-cell lung cancer: post-hoc analysis of an international, randomised, phase 3 trial (CALGB/Alliance 140503)

Altorki, N. K., Wang, X., Wigle, D. A., Gu, L., Darling, G., Ashrafi, A. S., Landrenau, R., Miller, D., Liberman, M., Jones, D. R., Keenan, R., Conti, M., Wright, G., Veit, L. J., Ramalingam, S. S., Kamel, M., Pass, H. I., Mitchell, J. D., Stinchcombe, T., Vokes, E. & 1 others, Kohman, L. J., Dec 1 2018, In : The Lancet Respiratory Medicine. 6, 12, p. 915-924 10 p.

Research output: Contribution to journalArticle

28 Scopus citations

The cost burden of clinically significant esophageal anastomotic leaks—a steep price to pay

Agzarian, J., Visscher, S. L., Knight, A. W., Allen, M. S., Cassivi, S. D., Nichols, F. C., Shen, K. R., Wigle, D. A. & Blackmon, S. H., Jan 1 2018, (Accepted/In press) In : Journal of Thoracic and Cardiovascular Surgery.

Research output: Contribution to journalArticle

6 Scopus citations
2017

A novel strategy to initiate a peroral endoscopic myotomy program

Reinersman, J. M., Wigle, D. A., Gostout, C. J., Song, L. M. W. K. & Blackmon, S. H., Oct 1 2017, In : European Journal of Cardio-thoracic Surgery. 52, 4, p. 686-691 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Clinical Trials in Thoracic Surgery: A Report From Ginsberg Day 2017 and Early Risers at STS 2017

Thoracic Surgery Trials Network, Aug 1 2017, In : Annals of Thoracic Surgery. 104, 2, p. 712-713 2 p.

Research output: Contribution to journalArticle

4 Scopus citations

Full-thickness oesophageal regeneration in pig using a polyurethane mucosal cell seeded graft

Barron, M. R., Blanco, E. W., Aho, J. M., Chakroff, J., Johnson, J., Cassivi, S. D., Carey, W. A. & Wigle, D. A., 2017, (Accepted/In press) In : Journal of Tissue Engineering and Regenerative Medicine.

Research output: Contribution to journalArticle

5 Scopus citations

Management of Multifocal Lung Cancer: Results of a Survey

Leventakos, K., Peikert, T. D., Midthun, D. E., Molina, J. R., Blackmon, S., Nichols, F. C., Garces, Y. I., Hallemeier, C., Murphy, S. J., Vasmatzis, G., Kratz, S. L., Holland, W. P., Thomas, C. F., Mullon, J. J., Shen, K. R., Cassivi, S. D., Marks, R. S., Aubry, M. C., Adjei, A., Yang, P. & 4 others, Allen, M. S., Edell, E., Wigle, D. A. & Mansfield, A., 2017, (Accepted/In press) In : Journal of Thoracic Oncology.

Research output: Contribution to journalArticle

8 Scopus citations

Microlobectomy: A Novel Form of Endoscopic Lobectomy

Dunning, J., Elsaegh, M., Nardini, M., Gillaspie, E. A., Petersen, R. H., Hansen, H. J., Helsel, B., Naase, H., Kornaszewska, M., Will, M. B., Walker, W. S., Wigle, D. A. & Blackmon, S. H., Jul 1 2017, In : Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery. 12, 4, p. 247-253 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Outcomes After Sleeve Lung Resections Versus Pneumonectomy in the United States

Abdelsattar, Z. M., Shen, K. R., Yendamuri, S., Cassivi, S., Nichols, F. C., Wigle, D. A., Allen, M. S. & Blackmon, S. H., 2017, (Accepted/In press) In : Annals of Thoracic Surgery.

Research output: Contribution to journalArticle

10 Scopus citations

Patient- and Cell Type-Specific Heterogeneity of Metformin Response

Asiedu, M. K., Barron, M., Aubry, M. C. & Wigle, D. A., 2017, (Accepted/In press) In : Basic and Clinical Pharmacology and Toxicology.

Research output: Contribution to journalArticle

4 Scopus citations
1 Scopus citations

Quantification of Etoposide Hypersensitivity: A Sensitive, Functional Method for Assessing Pluripotent Stem Cell Quality

Secreto, F. J., Li, X., Smith, A. J., Bruinsma, E. S., Perales-Clemente, E., Oommen, S., Hawse, G., Hrstka, S. C. L., Arendt, B. K., Brandt, E. B., Wigle, D. A. & Nelson, T. J., Oct 1 2017, In : Stem cells translational medicine. 6, 10, p. 1829-1839 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Safety of air travel in the immediate postoperative period after anatomic pulmonary resection

Cassivi, S. D., Pierson, K. E., Lechtenberg, B. J., Nichols, F. C., Shen, K. R., Allen, M. S. & Wigle, D. A., May 1 2017, In : Journal of Thoracic and Cardiovascular Surgery. 153, 5, p. 1191-1196.e1

Research output: Contribution to journalArticle

2 Scopus citations

Survival After Surgical Resection of Stage IV Esophageal Cancer

Saddoughi, S. A., Reinersman, J. M., Zhukov, Y. O., Taswell, J., Mara, K., Harmsen, S. W., Blackmon, S. H., Cassivi, S. D., Nichols, F., Shen, K. R., Wigle, D. A. & Allen, M. S., Jan 1 2017, In : Annals of Thoracic Surgery. 103, 1, p. 261-266 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

T category of non–small cell lung cancer invading the fissure to the adjacent lobe

Liu, M., Wigle, D. A., Wampfler, J. A., Dai, J., Stoddard, S. M., Xue, Z., Nichols, F. C., Jiang, G. & Yang, P., Nov 1 2017, In : Journal of Thoracic and Cardiovascular Surgery. 154, 5, p. 1777-1783.e3

Research output: Contribution to journalArticle

2 Scopus citations

The course of achalasia one to four decades after initial treatment

Sawas, T., Ravi, K., Geno, D. M., Enders, F. T., Pierce, K., Wigle, D. A. & Katzka, D. A., Feb 1 2017, In : Alimentary Pharmacology and Therapeutics. 45, 4, p. 553-560 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Treatment of Postsurgical Chylothorax

Reisenauer, J. S., Puig, C. A., Reisenauer, C. J., Allen, M. S., Bendel, E., Cassivi, S. D., Nichols, F. C., Shen, R. K., Wigle, D. A. & Blackmon, S. H., Jan 1 2017, (Accepted/In press) In : Annals of Thoracic Surgery.

Research output: Contribution to journalArticle

9 Scopus citations

Variation in Hospital Adoption Rates of Video-Assisted Thoracoscopic Lobectomy for Lung Cancer and the Effect on Outcomes

Abdelsattar, Z. M., Allen, M. S., Shen, K. R., Cassivi, S. D., Nichols, F. C., Wigle, D. A. & Blackmon, S. H., Feb 1 2017, In : Annals of Thoracic Surgery. 103, 2, p. 454-460 7 p.

Research output: Contribution to journalArticle

15 Scopus citations
2016

88P: Use of brain imaging in the management of patients with lymph node negative multifocal lung cancer

Leventakos, K., Mansfield, A., Blackmon, S., Cassivi, S., Shen, R., Nichols, F. C., Molina, J. R., Allen, M. S., Aubry, M. C. & Wigle, D. A., Apr 1 2016, In : Journal of Thoracic Oncology. 11, 4, p. S93-S94

Research output: Contribution to journalArticle

1 Scopus citations
17 Scopus citations

Closure of a recurrent bronchopleural fistula using a matrix seeded with patient-derived mesenchymal stem cells

Aho, J. M., Dietz, A. B., Radel, D. J., Butler, G. W., Thomas, M., Nelson, T. J., Carlsen, B. T., Cassivi, S. D., Resch, Z. T., Faubion, W. A. & Wigle, D. A., Oct 1 2016, In : Stem cells translational medicine. 5, 10, p. 1375-1379 5 p.

Research output: Contribution to journalArticle

11 Scopus citations

Esophagectomy Outcomes in the Endoscopic Mucosal Resection Era

Dickinson, K. J., Wang, K. K. N., Zhang, L., Allen, M. S., Cassivi, S. D., Nichols, F. C., Shen, R., Wigle, D. A. & Blackmon, S. H., 2016, (Accepted/In press) In : Annals of Thoracic Surgery.

Research output: Contribution to journalArticle

1 Scopus citations

External validation of the Ferguson pulmonary risk score for predicting major pulmonary complications after oesophagectomy

Matthew Reinersman, J., Allen, M. S., Deschamps, C., Ferguson, M. K., Nichols, F. C., Robert Shen, K., Wigle, D. A. & Cassivi, S. D., 2016, In : European Journal of Cardio-thoracic Surgery. 49, 1, p. 333-338 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Factors influencing length of stay after surgery for benign foregut disease

Dickinson, K. J., Taswell, J. B., Allen, M. S., Blackmon, S. H., Nichols, F. C., Shen, R., Wigle, D. A. & Cassivi, S. D., Jul 1 2016, In : European Journal of Cardio-thoracic Surgery. 50, 1, p. 124-129 6 p., ezv453.

Research output: Contribution to journalArticle

2 Scopus citations

Heterogeneity of Programmed Cell Death Ligand 1 Expression in Multifocal Lung Cancer

Mansfield, A., Murphy, S. J., Peikert, T. D., Yi, E. S., Vasmatzis, G., Wigle, D. A. & Aubry, M. C., May 1 2016, In : Clinical Cancer Research. 22, 9, p. 2177-2182 6 p.

Research output: Contribution to journalArticle

66 Scopus citations

Lymphadenectomy During Pulmonary Metastasectomy

Reinersman, J. M. & Wigle, D. A., Feb 1 2016, In : Thoracic Surgery Clinics. 26, 1, p. 35-40 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Nondestructive measurement of esophageal biaxial mechanical properties utilizing sonometry

Aho, J. M., Qiang, B., Wigle, D. A., Tschumperlin, D. J. & Urban, M. W., Jun 7 2016, In : Physics in Medicine and Biology. 61, 13, p. 4781-4795 15 p.

Research output: Contribution to journalArticle

1 Scopus citations

Optimal Timing of Urinary Catheter Removal After Thoracic Operations: A Randomized Controlled Study

Allen, M. S., Blackmon, S. H., Nichols, F. C., Cassivi, S. D., Harmsen, W. S., Lechtenberg, B., Pierson, K., Wigle, D. A. & Shen, K. R., 2016, (Accepted/In press) In : Annals of Thoracic Surgery.

Research output: Contribution to journalArticle

6 Scopus citations

Surgical resection of rare esophageal cancers

Saddoughi, S. A., Taswell, J., Harmsen, W. S., Inra, M. L., Blackmon, S. H., Nichols, F. C., Cassivi, S. D., Wigle, D. A., Shen, K. R. & Allen, M. S., Jan 1 2016, In : Annals of Thoracic Surgery. 101, 1, p. 311-315 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Survival Implications of Variation in the Thoroughness of Pathologic Lymph Node Examination in American College of Surgeons Oncology Group Z0030 (Alliance)

Osarogiagbon, R. U., Decker, P. A., Ballman, K., Wigle, D. A., Allen, M. S. & Darling, G. E., 2016, (Accepted/In press) In : Annals of Thoracic Surgery.

Research output: Contribution to journalArticle

27 Scopus citations

Tumor-free transplantation of Patient-Derived induced pluripotent stem cell progeny for customized islet regeneration

El Khatib, M. M., Ohmine, S., Jacobus, E. J., Tonne, J. M., Morsy, S. G., Holditch, S. J., Schreiber, C. A., Uetsuka, K., Fusaki, N., Wigle, D. A., Terzic, A., Kudva, Y. C. & Ikeda, Y. H., 2016, In : Stem cells translational medicine. 5, 5, p. 694-702 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Unplanned Readmission After Lung Resection: Complete Follow-Up in a 1-Year Cohort With Identification of Associated Risk Factors

Dickinson, K. J., Taswell, J. B., Allen, M. S., Blackmon, S. H., Nichols, F. C., Shen, R., Wigle, D. A. & Cassivi, S. D., 2016, (Accepted/In press) In : Annals of Thoracic Surgery.

Research output: Contribution to journalArticle

10 Scopus citations

Use of shear wave ultrasound vibrometry for detection of simulated esophageal malignancy in ex vivo porcine esophagi

Aho, J. M., Nenadic, I. Z., Aristizabal, S., Wigle, D. A., Tschumperlin, D. J. & Urban, M. W., Nov 23 2016, In : Biomedical Physics and Engineering Express. 2, 6, 065002.

Research output: Contribution to journalArticle

2015

¿Influyen el número y volumen de las biopsias pulmonares en el rendimiento diagnóstico en la enfermedad pulmonar intersticial? Análisis mediante índice de propensión

Translated title of the contribution: Do the number and volume of surgical lung biopsies influence the diagnostic yield in interstitial lung disease? A propensity score analysisFibla, J. J., Brunelli, A., Allen, M. S., Wigle, D. A., Shen, R., Nichols, F., Deschamps, C. & Cassivi, S. D., Feb 1 2015, In : Archivos de Bronconeumologia. 51, 2, p. 76-79 4 p.

Research output: Contribution to journalArticle

4 Scopus citations

Adjuvant radiotherapy for resectable locally advanced non-small cell lung cancer: Benefit or harm?

Martin, L. W., Darling, G. E. & Wigle, D. A., Dec 1 2015, In : Journal of Thoracic and Cardiovascular Surgery. 150, 6, p. 1407-1409 3 p.

Research output: Contribution to journalArticle

Bilobectomy Versus Lobectomy for Non-Small Cell Lung Cancer: A Comparative Study of Outcomes, Long-Term Survival, and Quality of Life

Xie, D., Deschamps, C., Shen, R. K., Deng, B., Wampfler, J. A., Cassivi, S. D., Nichols, F. C., Allen, M. S., Wigle, D. A. & Yang, P., Jul 1 2015, In : Annals of Thoracic Surgery. 100, 1, p. 242-250 9 p., 28066.

Research output: Contribution to journalArticle

9 Scopus citations

Biomarker-driven adjuvant targeted therapy for NSCLC-the ALCHEMIST trials

Oxnard, G. R., Watt, C., Wigle, D. A. & Boughey, J. C., Sep 1 2015, In : Bulletin of the American College of Surgeons. 100, 9, p. 25-27 3 p.

Research output: Contribution to journalArticle

2 Scopus citations