• 4099 Citations
  • 34 Scopus h-Index
19982020

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2020

Myoglobin for Detection of High-Risk Patients with Acute Myocarditis

Kottwitz, J., Bruno, K. A., Berg, J., Salomon, G. R., Fairweather, D. L., Elhassan, M., Baltensperger, N., Kissel, C. K., Lovrinovic, M., Baltensweiler, A., Schmied, C., Templin, C., Lima, J. A. C., Landmesser, U., Lüscher, T. F., Manka, R. & Heidecker, B., Jan 1 2020, (Accepted/In press) In : Journal of cardiovascular translational research.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2019

BPA Alters Estrogen Receptor Expression in the Heart After Viral Infection Activating Cardiac Mast Cells and T Cells Leading to Perimyocarditis and Fibrosis

Bruno, K. A., Mathews, J. E., Yang, A. L., Frisancho, J. A., Scott, A. J., Greyner, H. D., Molina, F. A., Greenaway, M. S., Cooper, G. M., Bucek, A., Morales-Lara, A. C., Hill, A. R., Mease, A. A., Di Florio, D. N., Sousou, J. M., Coronado, A. C., Stafford, A. R. & Fairweather, D. L., Sep 4 2019, In : Frontiers in Endocrinology. 10, 598.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Dilated cardiomyopathy

Schultheiss, H. P., Fairweather, D. L., Caforio, A. L. P., Escher, F., Hershberger, R. E., Lipshultz, S. E., Liu, P. P., Matsumori, A., Mazzanti, A., McMurray, J. & Priori, S. G., Dec 1 2019, In : Nature Reviews Disease Primers. 5, 1, 32.

Research output: Contribution to journalArticle

7 Scopus citations

Elevated sera sST2 is associated with heart failure in men ≤50 years old with myocarditis

Coronado, M. J., Bruno, K. A., Blauwet, L. A., Tschöpe, C., Cunningham, M. W., Pankuweit, S., Van Linthout, S., Jeon, E. S., McNamara, D. M., Krejćí, J., Bienertová-Vašků, J., Douglass, E. J., Abston, E. D., Bucek, A., Frisancho, J. A., Greenaway, M. S., Hill, A. R., Schultheiss, H. P., Cooper, L. T. & Fairweather, D., Jan 1 2019, In : Journal of the American Heart Association. 8, 2, e008968.

Research output: Contribution to journalArticle

15 Scopus citations

Self-reactive CD4+ IL-3+ T cells amplify autoimmune inflammation in myocarditis by inciting monocyte chemotaxis

Anzai, A., Mindur, J. E., Halle, L., Sano, S., Choi, J. L., He, S., McAlpine, C. S., Chan, C. T., Kahles, F., Valet, C., Fenn, A. M., Nairz, M., Rattik, S., Iwamoto, Y., Fairweather, D. L., Walsh, K., Libby, P., Nahrendorf, M. & Swirski, F. K., Feb 1 2019, In : Journal of Experimental Medicine. 216, 2, p. 369-383 15 p.

Research output: Contribution to journalArticle

7 Scopus citations
2018

Pulmonary arterial stiffness assessed by cardiovascular magnetic resonance imaging is a predictor of mild pulmonary arterial hypertension

Ray, J. C., Burger, C. D., Mergo, P., Safford, R., Blackshear, J., Austin, C., Fairweather, D., Heckman, M. G., Zeiger, T., Dubin, M. & Shapiro, B. P., Jun 22 2018, (Accepted/In press) In : International Journal of Cardiovascular Imaging. p. 1-12 12 p.

Research output: Contribution to journalArticle

3 Scopus citations
2017

Genome-wide association study of cardiotoxicity in the NCCTG N9831 (Alliance) adjuvant trastuzumab trial

Serie, D. J., Crook, J., Necela, B. M., Dockter, T. J., Wang, X., Asmann, Y., Fairweather, D., Bruno, K. A., Colon-Otero, G., Perez, E. A., Thompson, E. A. & Norton, N., 2017, In : Pharmacogenetics and Genomics. 27, 10, p. 378-385 8 p.

Research output: Contribution to journalArticle

14 Scopus citations
2015

Arsenic exposure and hepatitis E virus infection during pregnancy

Heaney, C. D., Kmush, B., Navas-Acien, A., Francesconi, K., Gössler, W., Schulze, K., Fairweather, D., Mehra, S., Nelson, K. E., Klein, S. L., Li, W., Ali, H., Shaikh, S., Merrill, R. D., Wu, L., West, K. P., Christian, P. & Labrique, A. B., Oct 1 2015, In : Environmental Research. 142, p. 273-280 8 p.

Research output: Contribution to journalArticle

17 Scopus citations
5 Scopus citations
2014

Complexities in the relationship between infection and autoimmunity

Root-Bernstein, R. & Fairweather, D., Jan 2014, In : Current Allergy and Asthma Reports. 14, 1, 407.

Research output: Contribution to journalArticle

42 Scopus citations

Low-dose mercury heightens early innate response to coxsackievirus infection in female mice

Penta, K. L., Fairweather, D. L., Shirley, D. L., Rose, N. R., Silbergeld, E. K. & Nyland, J. F., Jan 1 2014, In : Inflammation Research. 64, 1, p. 31-40 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Sex differences in translocator protein 18 kDa (TSPO) in the heart: Implications for imaging myocardial inflammation

Fairweather, D. L., Coronado, M. J., Garton, A. E., Dziedzic, J. L., Bucek, A., Cooper, L. T., Brandt, J. E., Alikhan, F. S., Wang, H., Endres, C. J., Choi, J., Pomper, M. G. & Guilarte, T. R., Mar 2014, In : Journal of cardiovascular translational research. 7, 2, p. 192-202 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

Unresolved issues in theories of autoimmune disease using myocarditis as a framework

Root-Bernstein, R. & Fairweather, D., Jun 1 2014, In : Journal of Theoretical Biology. 375, p. 101-123 23 p.

Research output: Contribution to journalArticle

26 Scopus citations
2013

Autoimmune myocarditis, valvulitis, and cardiomyopathy

Myers, J. M., Fairweather, D. L., Huber, S. A. & Cunningham, M. W., 2013, In : Current Protocols in Immunology. SUPPL.101, 15.14.

Research output: Contribution to journalArticle

23 Scopus citations

Fatal eosinophilic myocarditis develops in the absence of IFN-γand IL-17A

Barin, J. G., Baldeviano, G. C., Talor, M. V., Wu, L., Ong, S. F., De Fairweather, L., Bedja, D., Stickel, N. R., Fontes, J. A., Cardamone, A. B., Zheng, D., Gabrielson, K. L., Rose, N. R. & Čiháková, D., Oct 15 2013, In : Journal of Immunology. 191, 8, p. 4038-4047 10 p.

Research output: Contribution to journalArticle

28 Scopus citations

Sex and Gender Differences in Myocarditis and Dilated Cardiomyopathy

Fairweather, D. L., Cooper, L. T. & Blauwet, L. A., Jan 1 2013, In : Current Problems in Cardiology. 38, 1, p. 7-46 40 p.

Research output: Contribution to journalArticle

93 Scopus citations

TLR3 deficiency induces chronic inflammatory cardiomyopathy in resistant mice following coxsackievirus B3 infection: Role for IL-4

Abston, E. D., Coronado, M. J., Bucek, A., Onyimba, J. A., Brandt, J. E., Augusto Frisancho, J., Kim, E., Bedja, D., Sung, Y. K., Radtke, A. J., Gabrielson, K. L., Mitzner, W. & Fairweather, D. L., Feb 15 2013, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 304, 4, p. R267-R277

Research output: Contribution to journalArticle

27 Scopus citations
2012

IL-33 independently induces eosinophilic pericarditis and cardiac dilation ST2 improves cardiac function

Abston, E. D., Barin, J. G., Cihakova, D., Bucek, A., Coronado, M. J., Brandt, J. E., Kim, D. B. B., Georgakopoulos, D., Gabrielson, K. L., Mitzner, W. & Fairweather, D., May 2012, In : Circulation: Heart Failure. 5, 3, p. 366-375 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Low-dose inorganic mercury increases severity and frequency of chronic coxsackievirus-induced autoimmune myocarditis in mice

Nyland, J. F., Fairweather, D. L., Shirley, D. L., Davis, S. E., Rose, N. R. & Silbergeld, E. K., 2012, In : Toxicological Sciences. 125, 1, p. 134-143 10 p., kfr264.

Research output: Contribution to journalArticle

31 Scopus citations

Testosterone and interleukin-1β increase cardiac remodeling during coxsackievirus B3 myocarditis via serpin A 3n

Coronado, M. J., Brandt, J. E., Kim, E., Bucek, A., Bedja, D., Abston, E. D., Shin, J., Gabrielson, K. L., Mitzner, W. & Fairweather, D., Apr 15 2012, In : American Journal of Physiology - Heart and Circulatory Physiology. 302, 8, p. H1726-H1736

Research output: Contribution to journalArticle

43 Scopus citations

Th2 regulation of viral myocarditis in mice: Different roles for TLR3 versus TRIF in progression to chronic disease

Abston, E. D., Coronado, M. J., Bucek, A., Bedja, D., Shin, J., Kim, J. B., Kim, E., Gabrielson, K. L., Georgakopoulos, D., Mitzner, W. & Fairweather, D., Jan 3 2012, In : Clinical and Developmental Immunology. 2012, 129486.

Research output: Contribution to journalArticle

52 Scopus citations

The composition and signaling of the IL-35 receptor are unconventional

Collison, L. W., Delgoffe, G. M., Guy, C. S., Vignali, K. M., Chaturvedi, V., Fairweather, D., Satoskar, A. R., Garcia, K. C., Hunter, C. A., Drake, C. G., Murray, P. J. & Vignali, D. A. A., Mar 1 2012, In : Nature immunology. 13, 3, p. 290-299 10 p.

Research output: Contribution to journalArticle

237 Scopus citations
2011

The innate immune response to coxsackievirus B3 predicts progression to cardiovascular disease and heart failure in male mice

Onyimba, J. A., Coronado, M. J., Garton, A. E., Kim, J. B., Bucek, A., Bedja, D., Gabrielson, K. L., Guilarte, T. R. & Fairweather, D. L., Dec 1 2011, In : Biology of Sex Differences. 2, 1, 2.

Research output: Contribution to journalArticle

26 Scopus citations
2009

Alternatively activated macrophages in infection and autoimmunity

Fairweather, D. L. & Cihakova, D., Nov 1 2009, In : Journal of Autoimmunity. 33, 3-4, p. 222-230 9 p.

Research output: Contribution to journalArticle

207 Scopus citations

Cumulative childhood stress and autoimmune diseases in adults

Dube, S. R., Fairweather, D., Pearson, W. S., Felitti, V. J., Anda, R. F. & Croft, J. B., Jan 1 2009, In : Psychosomatic Medicine. 71, 2, p. 243-250 8 p.

Research output: Contribution to journalArticle

316 Scopus citations

Gonadectomy of male BALB/c mice increases Tim-3+ alternatively activated M2 macrophages, Tim-3+ T cells, Th2 cells and Treg in the heart during acute coxsackievirus-induced myocarditis

Frisancho-Kiss, S., Coronado, M. J., Frisancho, J. A., Lau, V. M., Rose, N. R., Klein, S. L. & Fairweather, D. L., Jul 1 2009, In : Brain, Behavior, and Immunity. 23, 5, p. 649-657 9 p.

Research output: Contribution to journalArticle

75 Scopus citations
2008

Interleukin-13 protects against experimental autoimmune myocarditis by regulating macrophage differentiation

Cihakova, D., Barin, J. G., Afanasyeva, M., Kimura, M., Fairweather, D. L., Berg, M., Talor, M. V., Baldeviano, G. C., Frisancho, S., Gabrielson, K., Bedja, D. & Rose, N. R., May 2008, In : American Journal of Pathology. 172, 5, p. 1195-1208 14 p.

Research output: Contribution to journalArticle

100 Scopus citations
2007

Coxsackievirus-induced myocarditis in mice: A model of autoimmune disease for studying immunotoxicity

Fairweather, D. L. & Rose, N. R., Jan 1 2007, In : Methods. 41, 1, p. 118-122 5 p.

Research output: Contribution to journalArticle

128 Scopus citations

Cutting edge: Cross-regulation by TLR4 and T cell Ig mucin-3 determines sex differences in inflammatory heart disease

Frisancho-Kiss, S., Davis, S. E., Nyland, J. F., Frisancho, J. A., Cihakova, D., Barrett, M. A., Rose, N. R. & Fairweather, D. L., Jun 1 2007, In : Journal of Immunology. 178, 11, p. 6710-6714 5 p.

Research output: Contribution to journalArticle

Open Access
134 Scopus citations
2006

Complement receptor 1 and 2 deficiency increases coxsackievirus B3-induced myocarditis, dilated cardiomyopathy, and heart failure by increasing macrophages, IL-1β, and immune complex deposition in the heart

Fairweather, D. L., Frisancho-Kiss, S., Njoku, D. B., Nyland, J. F., Kaya, Z., Yusung, S. A., Davis, S. E., Frisancho, J. A., Barrett, M. A. & Rose, N. R., Mar 15 2006, In : Journal of Immunology. 176, 6, p. 3516-3524 9 p.

Research output: Contribution to journalArticle

Open Access
51 Scopus citations

Cutting edge: T cell Ig mucin-3 reduces inflammatory heart disease by increasing CTLA-4 during innate immunity

Frisancho-Kiss, S., Nyland, J. F., Davis, S. E., Barrett, M. A., Gatewood, S. J. L., Njoku, D. B., Cihakova, D., Silbergeld, E. K., Rose, N. R. & Fairweather, D. L., Jun 1 2006, In : Journal of Immunology. 176, 11, p. 6411-6415 5 p.

Research output: Contribution to journalArticle

Open Access
101 Scopus citations

Sex differences in coxsackievirus B3-induced myocarditis: IL-12Rβ1 signaling and IFN-γ increase inflammation in males independent from STAT4

Frisancho-Kiss, S., Nyland, J. F., Davis, S. E., Augusto Frisancho, J., Barrett, M. A., Rose, N. R. & Fairweather, D. L., Dec 18 2006, In : Brain Research. 1126, 1, p. 139-147 9 p.

Research output: Contribution to journalArticle

48 Scopus citations
2005

A novel model of drug hapten-induced hepatitis with increased mast cells in the BALB/c mouse

Njoku, D. B., Talor, M. V., Fairweather, D., Frisancho-Kiss, S., Odumade, O. A. & Rose, N. R., Apr 2005, In : Experimental and Molecular Pathology. 78, 2, p. 87-100 14 p.

Research output: Contribution to journalArticle

22 Scopus citations

IL-12 protects against coxsackievirus B3-induced myocarditis by increasing IFN-γ and macrophage and neutrophil populations in the heart

Fairweather, D. L., Frisancho-Kiss, S., Yusung, S. A., Barrett, M. A., Davis, S. E., Steele, R. A., Gatewood, S. J. L. & Rose, N. R., Jan 1 2005, In : Journal of Immunology. 174, 1, p. 261-269 9 p.

Research output: Contribution to journalArticle

Open Access
102 Scopus citations

Impaired up-regulation of CD25 on CD4+ T cells in IFN-γ knockout mice is associated with progression of myocarditis to heart failure

Afanasyeva, M., Georgakopoulos, D., Belardi, D. F., Bedja, D., Fairweather, D. L., Wang, Y., Kaya, Z., Gabrielson, K. L., Rodriguez, E. R., Caturegli, P., Kass, D. A. & Rose, N. R., Jan 4 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 1, p. 180-185 6 p.

Research output: Contribution to journalArticle

63 Scopus citations
2004

Animal models for autoimmune myocarditis and autoimmune thyroiditis.

Ciháková, D., Sharma, R. B., Fairweather, D. L., Afanasyeva, M. & Rose, N. R., 2004, In : Methods in molecular medicine. 102, p. 175-193 19 p.

Research output: Contribution to journalArticle

62 Scopus citations

Infectious etiologies of chronic diseases: focus on women.

O'Connor, S., Fairweather, D. L., Pearce, B. D. & Rasmussen, S., Nov 2004, In : Emerging infectious diseases. 10, 11, p. 2028-2029 2 p.

Research output: Contribution to journalArticle

Open Access

Interferon-γ protects against chronic viral myocarditis by reducing mast cell degranulation, fibrosis, and the profibrotic cytokines transforming growth factor-β1, interleukin-1β, and interleukin-4 in the heart

Fairweather, D. L., Frisancho-Kiss, S., Yusung, S. A., Barrett, M. A., Davis, S. E., Gatewood, S. J. L., Njoku, D. B. & Rose, N. R., Dec 2004, In : American Journal of Pathology. 165, 6, p. 1883-1894 12 p.

Research output: Contribution to journalArticle

140 Scopus citations

Mast cells and innate cytokines are associated with susceptibility to autoimmune heart disease following Coxsackievirus B3 infection

Fairweather, D., Frisancho-Kiss, S., Gatewood, S., Njoku, D., Steele, R., Barrett, M. & Rose, N. R., Mar 1 2004, In : Autoimmunity. 37, 2, p. 131-145 15 p.

Research output: Contribution to journalArticle

71 Scopus citations

Novel model of constrictive pericarditis associated with autoimmune heart disease in interferon-γ-knockout mice

Afanasyeva, M., Georgakopoulos, D., Fairweather, D. L., Caturegli, P., Kass, D. A. & Rose, N. R., Nov 2 2004, In : Circulation. 110, 18, p. 2910-2917 8 p.

Research output: Contribution to journalArticle

23 Scopus citations

Women and autoimmune diseases

Fairweather, D. L. & Rose, N. R., Nov 2004, In : Emerging infectious diseases. 10, 11, p. 2005-2011 7 p.

Research output: Contribution to journalArticle

Open Access
103 Scopus citations
2003

IL-12 receptor β1 and toll-like receptor 4 increase IL-1β- and IL-18-associated myocarditis and coxsackievirus replication

Fairweather, D. L., Yusung, S., Frisancho, S., Barrett, M., Gatewood, S., Steele, R. & Rose, N. R., May 1 2003, In : Journal of Immunology. 170, 9, p. 4731-4737 7 p.

Research output: Contribution to journalArticle

166 Scopus citations
2002

Characterisation of murine cytomegalovirus myocarditis: Cellular infiltration of the heart and virus persistence

Lenzo, J. C., Fairweather, D. L., Cull, V., Shellam, G. R. & James, C. M., Jun 1 2002, In : Journal of Molecular and Cellular Cardiology. 34, 6, p. 629-640 12 p.

Research output: Contribution to journalArticle

49 Scopus citations

Type I diabetes: Virus infection or autoimmune disease?

Fairweather, D. L. & Rose, N. R., Jan 1 2002, In : Nature immunology. 3, 4, p. 338-340 3 p.

Research output: Contribution to journalArticle

40 Scopus citations
2001

Contribution of the innate immune system to autoimmune myocarditis: A role for complement

Kaya, Z., Afanasyeva, M., Wang, Y., Dohmen, K. M., Schlichting, J., Tretter, T., Fairweather, D. L., Holers, V. M. & Rose, N. R., Aug 25 2001, In : Nature immunology. 2, 8, p. 739-745 7 p.

Research output: Contribution to journalArticle

139 Scopus citations

From infection to autoimmunity

Fairweather, D., Kaya, Z., Shellam, G. R., Lawson, C. M. & Rose, N. R., Jan 1 2001, In : Journal of Autoimmunity. 16, 3, p. 175-186 12 p.

Research output: Contribution to journalArticle

239 Scopus citations

Immunomodulation of murine cytomegalovirus-induced myocarditis in mice treated with lipopolysaccharide and tumor necrosis factor

Lenzo, J. C., Fairweather, D. L., Shellam, G. R. & Lawson, C. M., Oct 10 2001, In : Cellular Immunology. 213, 1, p. 52-61 10 p.

Research output: Contribution to journalArticle

21 Scopus citations
1998

Wild isolates of murine cytomegalovirus induce myocarditis and antibodies that cross-react with virus and cardiac myosin

Fairweather, D., Lawson, C. M., Chapman, A. J., Brown, C. M. S., Booth, T. W. M., Papadimitriou, J. M. & Shellam, G. R., Jun 22 1998, In : Immunology. 94, 2, p. 263-270 8 p.

Research output: Contribution to journalArticle

42 Scopus citations