• 3647 Citations
  • 30 Scopus h-Index
19982019
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Research Output 1998 2019

2019

Dilated cardiomyopathy

Schultheiss, H. P., Fairweather, D., Caforio, A. L. P., Escher, F., Hershberger, R. E., Lipshultz, S. E., Liu, P. P., Matsumori, A., Mazzanti, A., McMurray, J. & Priori, S. G., Dec 1 2019, In : Nature Reviews Disease Primers. 5, 1, 32.

Research output: Contribution to journalArticle

Dilated Cardiomyopathy
Inflammation
Ventricular Dysfunction
Endocrine System Diseases
Desmosomes
2 Citations (Scopus)

Elevated Sera sST 2 Is Associated With Heart Failure in Men ≤50 Years Old With Myocarditis

Coronado, M. J., Bruno, K. A., Blauwet, L. A., Tschöpe, C., Cunningham, M. W., Pankuweit, S., van Linthout, S., Jeon, E. S., McNamara, D. M., Krejčí, J., Bienertová-Vašků, J., Douglass, E. J., Abston, E. D., Bucek, A., Frisancho, J. A., Greenaway, M. S., Hill, A. R., Schultheiss, H. P., Cooper, L. T. J. & Fairweather, D., Jan 22 2019, In : Journal of the American Heart Association. 8, 2, p. e008968

Research output: Contribution to journalArticle

Myocarditis
Heart Failure
Serum
Sex Characteristics
Testosterone
3 Citations (Scopus)

Self-reactive CD4 + IL-3 + T cells amplify autoimmune inflammation in myocarditis by inciting monocyte chemotaxis

Anzai, A., Mindur, J. E., Halle, L., Sano, S., Choi, J. L., He, S., McAlpine, C. S., Chan, C. T., Kahles, F., Valet, C., Fenn, A. M., Nairz, M., Rattik, S., Iwamoto, Y., Fairweather, D., Walsh, K., Libby, P., Nahrendorf, M. & Swirski, F. K., Feb 4 2019, In : The Journal of experimental medicine. 216, 2, p. 369-383 15 p.

Research output: Contribution to journalArticle

Interleukin-3
Myocarditis
Chemotaxis
Monocytes
Inflammation
2018
1 Citation (Scopus)

Pulmonary arterial stiffness assessed by cardiovascular magnetic resonance imaging is a predictor of mild pulmonary arterial hypertension

Ray, J. C., Burger, C. D., Mergo, P., Safford, R., Blackshear, J., Austin, C., Fairweather, D., Heckman, M. G., Zeiger, T., Dubin, M. & Shapiro, B. P., Jun 22 2018, (Accepted/In press) In : International Journal of Cardiovascular Imaging. p. 1-12 12 p.

Research output: Contribution to journalArticle

Vascular Stiffness
Pulmonary Hypertension
Magnetic Resonance Imaging
Lung
Magnetic Resonance Spectroscopy
2 Citations (Scopus)

Sex differences in pulmonary arterial hypertension: Role of infection and autoimmunity in the pathogenesis of disease

Batton, K. A., Austin, C. O., Bruno, K. A., Burger, C. D., Shapiro, B. P. & Fairweather, D., Apr 18 2018, In : Biology of Sex Differences. 9, 1, 15.

Research output: Contribution to journalReview article

hypertension
Autoimmunity
Pulmonary Hypertension
Sex Characteristics
Disease
2017

Cellular Immunity: A Role for Cytokines

Fairweather, D., Afanasyeva, M. & Rose, N. R., 2017, Handbook of Systemic Autoimmune Diseases. Elsevier Ltd, Vol. 14. p. 1-29 29 p. (Handbook of Systemic Autoimmune Diseases; vol. 14).

Research output: Chapter in Book/Report/Conference proceedingChapter

Myocarditis
Cellular Immunity
Cytokines
Waste Products
Dilated Cardiomyopathy
8 Citations (Scopus)

Genome-wide association study of cardiotoxicity in the NCCTG N9831 (Alliance) adjuvant trastuzumab trial

Serie, D. J., Crook, J., Necela, B. M., Dockter, T. J., Wang, X., Asmann, Y., Fairweather, D., Bruno, K. A., Colon-Otero, G., Perez, E. A., Thompson, E. A. & Norton, N., 2017, In : Pharmacogenetics and Genomics. 27, 10, p. 378-385 8 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Single Nucleotide Polymorphism
Stroke Volume
Paclitaxel
Anthracyclines
1 Citation (Scopus)

Sex Determines Cardiac Myocyte Stretch and Relaxation

Coronado, M. J., Fairweather, D. & Bruno, K. A., Oct 1 2017, In : Circulation: Cardiovascular Genetics. 10, 5, e001950.

Research output: Contribution to journalEditorial

Myofibrils
Menopause
Transcriptome
Cardiac Myocytes
Sex Characteristics
2016
4 Citations (Scopus)

Sex Hormone Receptor Expression in the Immune System

Buskiewicz, I. A., Huber, S. A. & Fairweather, D., May 16 2016, Sex Differences In Physiology. Elsevier Inc., p. 45-60 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Gonadal Steroid Hormones
Immune System
Mast Cells
Dendritic Cells
B-Lymphocytes
2015
12 Citations (Scopus)

Arsenic exposure and hepatitis E virus infection during pregnancy

Heaney, C. D., Kmush, B., Navas-Acien, A., Francesconi, K., Gössler, W., Schulze, K., Fairweather, D., Mehra, S., Nelson, K. E., Klein, S. L., Li, W., Ali, H., Shaikh, S., Merrill, R. D., Wu, L., West, K. P., Christian, P. & Labrique, A. B., Oct 1 2015, In : Environmental Research. 142, p. 273-280 8 p.

Research output: Contribution to journalArticle

Hepatitis E virus
hepatitis
Arsenic
Virus Diseases
Viruses
4 Citations (Scopus)

Autoimmune skin diseases: Role of sex hormones, vitamin d, and menopause

Fairweather, D., Jan 1 2015, Skin, Mucosa and Menopause: Management of Clinical Issues. Springer Berlin Heidelberg, p. 359-381 23 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Gonadal Steroid Hormones
Menopause
Skin Diseases
Vitamins
Autoimmune Diseases
3 Citations (Scopus)
Chemokine CCL2
Myocarditis
Nanoparticles
Small Interfering RNA
Autoimmune Diseases
30 Citations (Scopus)

Sex differences in inflammation during atherosclerosis

Fairweather, D., Feb 2 2015, In : Clinical Medicine Insights: Cardiology. 2014, p. 49-59 11 p.

Research output: Contribution to journalReview article

Sex Characteristics
Atherosclerosis
Inflammation
Tunica Intima
Precision Medicine
27 Citations (Scopus)

Sex differences in Sjögren's syndrome: A comprehensive review of immune mechanisms

Brandt, J. E., Priori, R., Valesini, G. & Fairweather, D., Nov 3 2015, In : Biology of Sex Differences. 6, 1, 37.

Research output: Contribution to journalReview article

Sex Characteristics
Lacrimal Apparatus
Salivary Glands
Disease
Autoimmune Diseases

Viral Myocarditis and Dilated Cardiomyopathy: Mechanisms of Cardiac Injury, Inflammation, and Fibrosis

Buskiewicz, I., Huber, S. & Fairweather, D., Oct 27 2015, Vascular Responses to Pathogens. Elsevier Inc., p. 149-159 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Myocarditis
Dilated Cardiomyopathy
Fibrosis
Inflammation
Autoimmunity
2014
4 Citations (Scopus)

Biomarker and more: Can translocator protein 18 kDa predict recovery from brain injury and myocarditis?

Fairweather, D., Guilarte, T. R. & Cooper, L. T. J., 2014, In : Biomarkers in Medicine. 8, 5, p. 605-607 3 p.

Research output: Contribution to journalArticle

GABA Receptors
Recovery of Function
Myocarditis
Biomarkers
Sex Characteristics
26 Citations (Scopus)

Complexities in the relationship between infection and autoimmunity

Root-Bernstein, R. & Fairweather, D., Jan 2014, In : Current Allergy and Asthma Reports. 14, 1, 407.

Research output: Contribution to journalArticle

Autoimmunity
Autoimmune Diseases
Infection
Innate Immunity
Molecular Mimicry
1 Citation (Scopus)

Low-dose mercury heightens early innate response to coxsackievirus infection in female mice

Penta, K. L., Fairweather, D., Shirley, D. L., Rose, N. R., Silbergeld, E. K. & Nyland, J. F., 2014, In : Inflammation Research. 64, 1, p. 31-40 10 p.

Research output: Contribution to journalArticle

Coxsackievirus Infections
Mercury
Macrophages
Myocarditis
Spleen
14 Citations (Scopus)

Sex differences in translocator protein 18 kDa (TSPO) in the heart: Implications for imaging myocardial inflammation

Fairweather, D., Coronado, M. J., Garton, A. E., Dziedzic, J. L., Bucek, A., Cooper, L. T. J., Brandt, J. E., Alikhan, F. S., Wang, H., Endres, C. J., Choi, J., Pomper, M. G. & Guilarte, T. R., 2014, In : Journal of Cardiovascular Translational Research. 7, 2, p. 192-202 11 p.

Research output: Contribution to journalArticle

Myocarditis
Sex Characteristics
Inflammation
Enterovirus
Proteins
18 Citations (Scopus)

Unresolved issues in theories of autoimmune disease using myocarditis as a framework

Root-Bernstein, R. & Fairweather, D., Jun 1 2014, In : Journal of Theoretical Biology. 375, p. 101-123 23 p.

Research output: Contribution to journalArticle

Myocarditis
myocarditis
autoimmune diseases
Autoimmune Diseases
Theoretical Models
2013
20 Citations (Scopus)

Autoimmune myocarditis, valvulitis, and cardiomyopathy

Myers, J. M., Fairweather, D., Huber, S. A. & Cunningham, M. W., 2013, In : Current Protocols in Immunology. SUPPL.101, 15.14.

Research output: Contribution to journalArticle

Cardiac Myosins
Myocarditis
Cardiomyopathies
Myocardium
Animal Disease Models

Autoimmune myocarditis, valvulitis, and cardiomyopathy.

Myers, J. M., Fairweather, D., Huber, S. A. & Cunningham, M. W., 2013, In : Current protocols in immunology / edited by John E. Coligan ... [et al.]. Chapter 15

Research output: Contribution to journalArticle

Cardiac Myosins
Myocarditis
Cardiomyopathies
Myocardium
Animal Disease Models
23 Citations (Scopus)

Fatal eosinophilic myocarditis develops in the absence of IFN-γand IL-17A

Barin, J. G., Baldeviano, G. C., Talor, M. V., Wu, L., Ong, S. F., Fairweather, D., Bedja, D., Stickel, N. R., Fontes, J. A., Cardamone, A. B., Zheng, D., Gabrielson, K. L., Rose, N. R. & Čiháková, D., Oct 15 2013, In : Journal of Immunology. 191, 8, p. 4038-4047 10 p.

Research output: Contribution to journalArticle

Interleukin-17
Myocarditis
Eosinophils
Heart Diseases
Cardiac Myosins
76 Citations (Scopus)

Sex and Gender Differences in Myocarditis and Dilated Cardiomyopathy

Fairweather, D., Cooper, L. T. J. & Blauwet, L. A., Jan 2013, In : Current Problems in Cardiology. 38, 1, p. 7-46 40 p.

Research output: Contribution to journalArticle

Myocarditis
Dilated Cardiomyopathy
Sex Characteristics
Peripartum Period
Knowledge Management
25 Citations (Scopus)

TLR3 deficiency induces chronic inflammatory cardiomyopathy in resistant mice following coxsackievirus B3 infection: Role for IL-4

Abston, E. D., Coronado, M. J., Bucek, A., Onyimba, J. A., Brandt, J. E., Augusto Frisancho, J., Kim, E., Bedja, D., Sung, Y. K., Radtke, A. J., Gabrielson, K. L., Mitzner, W. & Fairweather, D., Feb 15 2013, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 304, 4

Research output: Contribution to journalArticle

Coxsackievirus Infections
Myocarditis
Cardiomyopathies
Interleukin-4
Dilated Cardiomyopathy
9 Citations (Scopus)

We see only what we look for: Imaging cardiac inflammation

Cooper, L. T. J. & Fairweather, D., Mar 2013, In : Circulation: Cardiovascular Imaging. 6, 2, p. 165-166 2 p.

Research output: Contribution to journalArticle

Fluorocarbons
Fluorine
Myocarditis
Dilated Cardiomyopathy
Myeloid Cells
2012
26 Citations (Scopus)

Autoimmune heart disease: Role of sex hormones and autoantibodies in disease pathogenesis

Fairweather, D., Petri, M. A., Coronado, M. J. & Cooperr, L. T., Mar 2012, In : Expert Review of Clinical Immunology. 8, 3, p. 269-284 16 p.

Research output: Contribution to journalReview article

Gonadal Steroid Hormones
Autoantibodies
Autoimmune Diseases
Heart Diseases
Cardiovascular Diseases
21 Citations (Scopus)

IL-33 independently induces eosinophilic pericarditis and cardiac dilation ST2 improves cardiac function

Abston, E. D., Barin, J. G., Cihakova, D., Bucek, A., Coronado, M. J., Brandt, J. E., Kim, D. B. B., Georgakopoulos, D., Gabrielson, K. L., Mitzner, W. & Fairweather, D., May 2012, In : Circulation: Heart Failure. 5, 3, p. 366-375 10 p.

Research output: Contribution to journalArticle

Pericarditis
Dilatation
Eosinophilia
Myocarditis
Interleukin-1
28 Citations (Scopus)

Low-dose inorganic mercury increases severity and frequency of chronic coxsackievirus-induced autoimmune myocarditis in mice

Nyland, J. F., Fairweather, D., Shirley, D. L., Davis, S. E., Rose, N. R. & Silbergeld, E. K., 2012, In : Toxicological Sciences. 125, 1, p. 134-143 10 p., kfr264.

Research output: Contribution to journalArticle

Enterovirus
Myocarditis
Mercury
Dilated Cardiomyopathy
Coxsackievirus Infections
61 Citations (Scopus)

Pathogenesis and diagnosis of myocarditis

Elamm, C., Fairweather, D. & Cooper, L. T. J., Jun 2012, In : Heart. 98, 11, p. 835-840 6 p.

Research output: Contribution to journalArticle

Myocarditis
Dilated Cardiomyopathy
Heart Failure
Gonadal Steroid Hormones
Routine Diagnostic Tests
4 Citations (Scopus)

Republished: Pathogenesis and diagnosis of myocarditis

Elamm, C., Fairweather, D. & Cooper, L. T. J., Sep 2012, In : Postgraduate Medical Journal. 88, 1043, p. 539-544 6 p.

Research output: Contribution to journalArticle

Myocarditis
Dilated Cardiomyopathy
Heart Failure
Gonadal Steroid Hormones
Routine Diagnostic Tests
40 Citations (Scopus)

Testosterone and interleukin-1β increase cardiac remodeling during coxsackievirus B3 myocarditis via serpin A 3n

Coronado, M. J., Brandt, J. E., Kim, E., Bucek, A., Bedja, D., Abston, E. D., Shin, J., Gabrielson, K. L., Mitzner, W. & Fairweather, D., Apr 15 2012, In : American Journal of Physiology - Heart and Circulatory Physiology. 302, 8

Research output: Contribution to journalArticle

Serpins
Enterovirus
Myocarditis
Interleukin-1
Testosterone
49 Citations (Scopus)

Th2 regulation of viral myocarditis in mice: Different roles for TLR3 versus TRIF in progression to chronic disease

Abston, E. D., Coronado, M. J., Bucek, A., Bedja, D., Shin, J., Kim, J. B., Kim, E., Gabrielson, K. L., Georgakopoulos, D., Mitzner, W. & Fairweather, D., 2012, In : Clinical and Developmental Immunology. 2012, 129486.

Research output: Contribution to journalArticle

Myocarditis
Chronic Disease
Enterovirus
Toll-Like Receptor 3
Virus Diseases
203 Citations (Scopus)

The composition and signaling of the IL-35 receptor are unconventional

Collison, L. W., Delgoffe, G. M., Guy, C. S., Vignali, K. M., Chaturvedi, V., Fairweather, D., Satoskar, A. R., Garcia, K. C., Hunter, C. A., Drake, C. G., Murray, P. J. & Vignali, D. A. A., Mar 2012, In : Nature Immunology. 13, 3, p. 290-299 10 p.

Research output: Contribution to journalArticle

Interleukin Receptors
Interleukins
Interleukin-12
T-Lymphocytes
STAT4 Transcription Factor
65 Citations (Scopus)

Update on coxsackievirus B3 myocarditis

Fairweather, D., Stafford, K. A. & Sung, Y. K., Jul 2012, In : Current Opinion in Rheumatology. 24, 4, p. 401-407 7 p.

Research output: Contribution to journalReview article

Enterovirus
Myocarditis
Dilated Cardiomyopathy
Regulatory T-Lymphocytes
Disease Progression
2011
26 Citations (Scopus)

The innate immune response to coxsackievirus B3 predicts progression to cardiovascular disease and heart failure in male mice

Onyimba, J. A., Coronado, M. J., Garton, A. E., Kim, J. B., Bucek, A., Bedja, D., Gabrielson, K. L., Guilarte, T. R. & Fairweather, D., 2011, In : Biology of Sex Differences. 2, 1, 2.

Research output: Contribution to journalArticle

Enterovirus
Innate Immunity
activation
Cardiovascular Diseases
Heart Failure
2009
196 Citations (Scopus)

Alternatively activated macrophages in infection and autoimmunity

Fairweather, D. & Cihakova, D., Nov 2009, In : Journal of Autoimmunity. 33, 3-4, p. 222-230 9 p.

Research output: Contribution to journalArticle

Antigen-Antibody Complex
Autoimmunity
Autoimmune Diseases
Fibrosis
Macrophages
280 Citations (Scopus)

Cumulative childhood stress and autoimmune diseases in adults

Dube, S. R., Fairweather, D., Pearson, W. S., Felitti, V. J., Anda, R. F. & Croft, J. B., Feb 2009, In : Psychosomatic Medicine. 71, 2, p. 243-250 8 p.

Research output: Contribution to journalArticle

Autoimmune Diseases
Hospitalization
Autoimmune Hemolytic Anemia
Domestic Violence
Divorce
68 Citations (Scopus)

Gonadectomy of male BALB/c mice increases Tim-3+ alternatively activated M2 macrophages, Tim-3+ T cells, Th2 cells and Treg in the heart during acute coxsackievirus-induced myocarditis

Frisancho-Kiss, S., Coronado, M. J., Frisancho, J. A., Lau, V. M., Rose, N. R., Klein, S. L. & Fairweather, D., Jul 2009, In : Brain, Behavior, and Immunity. 23, 5, p. 649-657 9 p.

Research output: Contribution to journalArticle

Th2 Cells
Enterovirus
Myocarditis
Macrophages
T-Lymphocytes
20 Citations (Scopus)

Sex differences in a murine model of Sjögren's syndrome

Iháková, D., Talor, M. V., Barin, J. G., Baldeviano, G. C., Fairweather, D., Rose, N. R. & Burek, C. L., Sep 2009, Contemporary Challenges in Autoimmunity. Vol. 1173. p. 378-383 6 p. (Annals of the New York Academy of Sciences; vol. 1173).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

T-cells
Sex Characteristics
Cells
B-Lymphocytes
Sialadenitis
2008
96 Citations (Scopus)

Interleukin-13 protects against experimental autoimmune myocarditis by regulating macrophage differentiation

Cihakova, D., Barin, J. G., Afanasyeva, M., Kimura, M., Fairweather, D., Berg, M., Talor, M. V., Baldeviano, G. C., Frisancho, S., Gabrielson, K., Bedja, D. & Rose, N. R., May 2008, In : American Journal of Pathology. 172, 5, p. 1195-1208 14 p.

Research output: Contribution to journalArticle

Interleukin-13
Myocarditis
Macrophages
Knockout Mice
T-Lymphocytes
27 Citations (Scopus)

Mast cells and inflammatory heart disease: Potential drug targets

Fairweather, D. & Frisancho-Kiss, S., Mar 2008, In : Cardiovascular and Hematological Disorders - Drug Targets. 8, 1, p. 80-90 11 p.

Research output: Contribution to journalReview article

Mast Cells
Heart Diseases
Pharmaceutical Preparations
Inflammation
Cell Degranulation
266 Citations (Scopus)

Sex differences in autoimmune disease from a pathological perspective

Fairweather, D., Frisancho-Kiss, S. & Rose, N. R., Sep 2008, In : American Journal of Pathology. 173, 3, p. 600-609 10 p.

Research output: Contribution to journalReview article

Sex Characteristics
Autoimmune Diseases
Pathology
Inflammation
Fibrosis
2007
115 Citations (Scopus)

Coxsackievirus-induced myocarditis in mice: A model of autoimmune disease for studying immunotoxicity

Fairweather, D. & Rose, N. R., Jan 2007, In : Methods. 41, 1, p. 118-122 5 p.

Research output: Contribution to journalArticle

Enterovirus
Myocarditis
Autoimmune Diseases
Heart Diseases
Dilated Cardiomyopathy
125 Citations (Scopus)

Cutting edge: Cross-regulation by TLR4 and T cell Ig mucin-3 determines sex differences in inflammatory heart disease

Frisancho-Kiss, S., Davis, S. E., Nyland, J. F., Frisancho, J. A., Cihakova, D., Barrett, M. A., Rose, N. R. & Fairweather, D., Jun 1 2007, In : Journal of Immunology. 178, 11, p. 6710-6714 5 p.

Research output: Contribution to journalArticle

Mucin-3
Sex Characteristics
Heart Diseases
T-Lymphocytes
Inflammation
2006
49 Citations (Scopus)

Complement receptor 1 and 2 deficiency increases coxsackievirus B3-induced myocarditis, dilated cardiomyopathy, and heart failure by increasing macrophages, IL-1β, and immune complex deposition in the heart

Fairweather, D., Frisancho-Kiss, S., Njoku, D. B., Nyland, J. F., Kaya, Z., Yusung, S. A., Davis, S. E., Frisancho, J. A., Barrett, M. A. & Rose, N. R., Mar 15 2006, In : Journal of Immunology. 176, 6, p. 3516-3524 9 p.

Research output: Contribution to journalArticle

Complement 3d Receptors
Complement C1
Complement Receptors
Enterovirus
Myocarditis
98 Citations (Scopus)

Cutting edge: T cell Ig mucin-3 reduces inflammatory heart disease by increasing CTLA-4 during innate immunity

Frisancho-Kiss, S., Nyland, J. F., Davis, S. E., Barrett, M. A., Gatewood, S. J. L., Njoku, D. B., Cihakova, D., Silbergeld, E. K., Rose, N. R. & Fairweather, D., Jun 1 2006, In : Journal of Immunology. 176, 11, p. 6411-6415 5 p.

Research output: Contribution to journalArticle

Mucin-3
Innate Immunity
Heart Diseases
T-Lymphocytes
Regulatory T-Lymphocytes
7 Citations (Scopus)

Immunopathogenesis of autoimmune diseases

Fairweather, D. & Rose, N. R., Jan 1 2006, Immunotoxicology and Immunopharmacology, Third Edition. CRC Press, p. 423-436 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Autoimmune Diseases
Immune System
Antigens
B-Lymphocytes
Lymphocytes
45 Citations (Scopus)

Sex differences in coxsackievirus B3-induced myocarditis: IL-12Rβ1 signaling and IFN-γ increase inflammation in males independent from STAT4

Frisancho-Kiss, S., Nyland, J. F., Davis, S. E., Augusto Frisancho, J., Barrett, M. A., Rose, N. R. & Fairweather, D., Dec 18 2006, In : Brain Research. 1126, 1, p. 139-147 9 p.

Research output: Contribution to journalArticle

Enterovirus
Myocarditis
Sex Characteristics
Inflammation
Interleukin-1
2005
21 Citations (Scopus)

A novel model of drug hapten-induced hepatitis with increased mast cells in the BALB/c mouse

Njoku, D. B., Talor, M. V., Fairweather, D., Frisancho-Kiss, S., Odumade, O. A. & Rose, N. R., Apr 2005, In : Experimental and Molecular Pathology. 78, 2, p. 87-100 14 p.

Research output: Contribution to journalArticle

Chemical and Drug Induced Liver Injury
Haptens
Mast Cells
Hepatitis
Anesthetics