Debabrata Mukhopadhyay, PhD

  • 15285 Citations
  • 62 Scopus h-Index
1991 …2020

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2004

Ablation of peripheral dopaminergic nerves stimulates malignant tumor growth by inducing vascular permeability factor/vascular endothelial growth factor-mediated angiogenesis

Basu, S., Sarkar, C., Chakroborty, D., Nagy, J., Mitra, R. B., Dasgupta, P. S. & Mukhopadhyay, D., Aug 15 2004, In : Cancer research. 64, 16, p. 5551-5555 5 p.

Research output: Contribution to journalArticle

72 Scopus citations

CD40-induced transcriptional activation of vascular endothelial growth factor involves a 68-bp region of the promoter containing a CpG island

Lapchak, P. H., Melter, M., Pal, S., Flaxenburg, J. A., Geehan, C., Frank, M. H., Mukhopadhyay, D. & Briscoe, D. M., Sep 1 2004, In : American Journal of Physiology - Renal Physiology. 287, 3 56-3, p. F512-F520

Research output: Contribution to journalArticle

10 Scopus citations

Effect of rapamycin alone and in combination with antiangiogenesis therapy in an orthotopic model of human pancreatic cancer

Stephan, S., Datta, K., Wang, E., Li, J., Brekken, R. A., Parangi, S., Thorpe, P. E. & Mukhopadhyay, D., Oct 15 2004, In : Clinical Cancer Research. 10, 20, p. 6993-7000 8 p.

Research output: Contribution to journalArticle

79 Scopus citations

Gold nanoparticles inhibit VEGF165-induced proliferation of HUVEC cells

Bhattacharya, R., Mukherjee, P., Xiong, Z., Atala, A., Soker, S. & Mukhopadhyay, D., Dec 1 2004, In : Nano Letters. 4, 12, p. 2479-2481 3 p.

Research output: Contribution to journalArticle

114 Scopus citations

Protein Kinase C ζ Transactivates Hypoxia-Inducible Factor α by Promoting Its Association with p300 in Renal Cancer

Datta, K., Li, J., Bhattacharya, R., Gasparian, L., Wang, E. & Mukhopadhyay, D., Jan 15 2004, In : Cancer research. 64, 2, p. 456-462 7 p.

Research output: Contribution to journalArticle

49 Scopus citations

Regulation of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF-A) expression in podocytes

Datta, K., Li, J., Ananth Karumanchi, S., Wang, E., Rondeau, E. & Mukhopadhyay, D., Oct 2004, In : Kidney international. 66, 4, p. 1471-1478 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

Role of Insulin Receptor Substrates and Protein Kinase C-ζ in Vascular Permeability Factor/Vascular Endothelial Growth Factor Expression in Pancreatic Cancer Cells

Neid, M., Datta, K., Stephan, S., Khanna, I., Pal, S., Shaw, L., White, M. & Mukhopadhyay, D., Feb 6 2004, In : Journal of Biological Chemistry. 279, 6, p. 3941-3948 8 p.

Research output: Contribution to journalArticle

43 Scopus citations
2003
61 Scopus citations

Neuropilin-1-mediated vascular permeability factor/vascular endothelial growth factor-dependent endothelial cell migration.

Wang, L., Zeng, H., Wang, P., Soker, S. & Mukhopadhyay, D., Dec 5 2003, In : The Journal of biological chemistry. 278, 49, p. 48848-48860 13 p.

Research output: Contribution to journalArticle

Open Access
167 Scopus citations

Proinflammatory functions of vascular endothelial growth factor in alloimmunity

Reinders, M. E. J., Sho, M., Izawa, A., Wang, P., Mukhopadhyay, D., Koss, K. E., Geehan, C. S., Luster, A. D., Sayegh, M. H. & Briscoe, D. M., Dec 2003, In : Journal of Clinical Investigation. 112, 11, p. 1655-1665 11 p.

Research output: Contribution to journalArticle

Open Access
174 Scopus citations
58 Scopus citations
2002
49 Scopus citations
6 Scopus citations

KDR stimulates endothelial cell migration through heterotrimeric G protein Gq/11-mediated activation of a small GTPase RhoA

Zeng, H., Zhao, D. & Mukhopadhyay, D., Nov 29 2002, In : Journal of Biological Chemistry. 277, 48, p. 46791-46798 8 p.

Research output: Contribution to journalArticle

96 Scopus citations

Myogenic Akt signaling regulates blood vessel recruitment during myofiber growth

Takahashi, A., Kureishi, Y., Yang, J., Luo, Z., Guo, K., Mukhopadhyay, D., Ivashchenko, Y., Branellec, D. & Walsh, K., Jun 22 2002, In : Molecular and cellular biology. 22, 13, p. 4803-4814 12 p.

Research output: Contribution to journalArticle

129 Scopus citations
2001

Cell surface glypicans are low-affinity endostatin receptors

Karumanchi, S. A., Jha, V., Ramchandran, R., Karihaloo, A., Tsiokas, L., Chan, B., Dhanabal, M., Hanai, J. I., Venkataraman, G., Shriver, Z., Keiser, N., Kalluri, R., Zeng, H., Mukhopadhyay, D., Chen, R. L., Lander, A. D., Hagihara, K., Yamaguchi, Y., Sasisekharan, R., Cantley, L. & 1 others, Sukhatme, V. P., Apr 2001, In : Molecular Cell. 7, 4, p. 811-822 12 p.

Research output: Contribution to journalArticle

256 Scopus citations

Central role of p53 on regulation of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) expression in mammary carcinoma

Pal, S., Datta, K. & Mukhopadhyay, D., Sep 15 2001, In : Cancer research. 61, 18, p. 6952-6957 6 p.

Research output: Contribution to journalArticle

167 Scopus citations

Role of Protein Kinase Cζ in Ras-mediated Transcriptional Activation of Vascular Permeability Factor/Vascular Endothelial Growth Factor Expression

Pal, S., Datta, K., Khosravi-Far, R. & Mukhopadhyay, D., Jan 26 2001, In : Journal of Biological Chemistry. 276, 4, p. 2395-2403 9 p.

Research output: Contribution to journalArticle

65 Scopus citations

The 104-123 amino acid sequence of the β-domain of von Hippel-Lindau gene product is sufficient to inhibit renal tumor growth and invasion

Datta, K., Sundberg, C., Karumanchi, S. A. & Mukhopadhyay, D., Mar 1 2001, In : Cancer research. 61, 5, p. 1768-1775 8 p.

Research output: Contribution to journalArticle

80 Scopus citations

The neurotransmitter dopamine inhibits angiogenesis induced by vascular permeability factor/vascular endothelial growth factor

Basu, S., Nagy, J. A., Pal, S., Vasile, E., Eckelhoefer, I. A., Bliss, V. S., Manseau, E. J., Dasgupta, P. S., Dvorak, H. F. & Mukhopadhyay, D., May 2001, In : Nature Medicine. 7, 5, p. 569-574 6 p.

Research output: Contribution to journalArticle

263 Scopus citations
125 Scopus citations
246 Scopus citations
2000

Inhibition of insulin-like growth factor-I-mediated cell signaling by the von Hippel-Lindau gene product in renal cancer

Datta, K., Nambudripad, R., Pal, S., Zhou, M., Cohen, H. T. & Mukhopadhyay, D., Jul 7 2000, In : Journal of Biological Chemistry. 275, 27, p. 20700-20706 7 p.

Research output: Contribution to journalArticle

75 Scopus citations

Ligation of CD40 induces the expression of vascular endothelial growth factor by endothelial cells and monocytes and promotes angiogenesis in vivo

Melter, M., Reinders, M. E. J., Sho, M., Pal, S., Geehan, C., Denton, M. D., Mukhopadhyay, D. & Briscoe, D. M., Dec 1 2000, In : Blood. 96, 12, p. 3801-3808 8 p.

Research output: Contribution to journalArticle

167 Scopus citations

Oncogenes and tumor angiogenesis: The HPV-16 E6 oncoprotein activates the vascular endothelial growth factor (VEGF) gene promoter in a p53 independent manner

López-Ocejo, O., Viloria-Petit, A., Bequet-Romero, M., Mukhopadhyay, D., Rak, J. & Kerbel, R. S., Sep 21 2000, In : Oncogene. 19, 40, p. 4611-4620 10 p.

Research output: Contribution to journalArticle

Open Access
162 Scopus citations

Retinoic acid selectively inhibits the vascular permeabilizing effect of VPF/VEGF, an early step in the angiogenic cascade

Pal, S., Iruela-Arispe, M. L., Harvey, V. S., Zeng, H., Nagy, J. A., Dvorak, H. F. & Mukhopadhyay, D., Jan 1 2000, In : Microvascular Research. 60, 2, p. 112-120 9 p.

Research output: Contribution to journalArticle

34 Scopus citations
1999

An important von Hippel-Lindau tumor suppressor domain mediates Sp1-binding and self-association

Cohen, H. T., Zhou, M., Welsh, A. M., Zarghamee, S., Scholz, H., Mukhopadhyay, D., Kishida, T., Zbar, B., Knebelmann, B. & Sukhatme, V. P., Dec 9 1999, In : Biochemical and Biophysical Research Communications. 266, 1, p. 43-50 8 p.

Research output: Contribution to journalArticle

42 Scopus citations

Role of protein kinase C isoforms in phorbol ester-induced vascular endothelial growth factor expression in human glioblastoma cells

Shih, S. C., Mullen, A., Abrams, K., Mukhopadhyay, D. & Claffey, K. P., May 28 1999, In : Journal of Biological Chemistry. 274, 22, p. 15407-15414 8 p.

Research output: Contribution to journalArticle

84 Scopus citations
1998

Activation of Sp1-mediated vascular permeability factor/vascular endothelial growth factor transcription requires specific interaction with protein kinase C ζ

Pal, S., Claffey, K. P., Cohen, H. T. & Mukhopadhyay, D., Oct 9 1998, In : Journal of Biological Chemistry. 273, 41, p. 26277-26280 4 p.

Research output: Contribution to journalArticle

155 Scopus citations
39 Scopus citations

Expression of fetal kidney growth factors in a kidney tumor line: Role of FGF2 in kidney development

Drummond, I. A., Mukhopadhyay, D. & Sukhatme, V. P., Nov 24 1998, In : Experimental Nephrology. 6, 6, p. 522-533 12 p.

Research output: Contribution to journalArticle

23 Scopus citations

High cell density induces vascular endothelial growth factor expression via protein tyrosine phosphorylation

Mukhopadhyay, D., Tsiokas, L. & Sukhatme, V. P., May 6 1998, In : Gene expression. 7, 1, p. 53-60 8 p.

Research output: Contribution to journalArticle

25 Scopus citations

Modulation of voltage-dependent Ca2+ channels in rabbit colonic smooth muscle cells by c-Src and focal adhesion kinase

Hu, X. Q., Singh, N., Mukhopadhyay, D. & Akbarali, H. I., Feb 27 1998, In : Journal of Biological Chemistry. 273, 9, p. 5337-5342 6 p.

Research output: Contribution to journalArticle

104 Scopus citations

Vascular permeability factor/vascular endothelial growth factor-mediated signaling in mouse mesentery vascular endothelium

Mukhopadhyay, D., Nagy, J. A., Manseau, E. J. & Dvorak, H. F., Mar 15 1998, In : Cancer research. 58, 6, p. 1278-1284 7 p.

Research output: Contribution to journalArticle

87 Scopus citations
1997
131 Scopus citations

The von Hippel-Lindau tumor suppressor gene product interacts with Sp1 to repress vascular endothelial growth factor promoter activity

Mukhopadhyay, D., Knebelmann, B., Cohen, H. T., Ananth, S. & Sukhatme, V. P., Sep 1997, In : Molecular and cellular biology. 17, 9, p. 5629-5639 11 p.

Research output: Contribution to journalArticle

Open Access
295 Scopus citations
1996
25 Scopus citations

Tyrosine kinase-dependent modulation of calcium entry in rabbit colonic muscularis mucosae

Hatakeyama, N., Mukhopadhyay, D., Goyal, R. K. & Akbarali, H. I., Jun 1 1996, In : American Journal of Physiology - Cell Physiology. 270, 6 39-6, p. C1780-C1789

Research output: Contribution to journalArticle

37 Scopus citations
1995

Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation

Mukhopadhyay, D., Tsiokas, L., Zhou, X. M., Foster, D., Brugge, J. S. & Sukhatme, V. P., Jan 1 1995, In : Nature. 375, 6532, p. 577-581 5 p.

Research output: Contribution to journalArticle

519 Scopus citations

Wild-Type p53 and v-Src Exert Opposing Influences on Human Vascular Endothelial Growth Factor Gene Expression

Mukhopadhyay, D., Tsiokas, L. & Sukhatme, V. P., Dec 15 1995, In : Cancer research. 55, 24, p. 6161-6165 5 p.

Research output: Contribution to journalArticle

393 Scopus citations
1994

3-Aminobenzamide delays rejoining of DNA strand breaks in γ-irradiated lymphocytes from patients with breast cancer and not cervical cancer

Mukhopadhyay, D., Anant, S. & Mukherji, S., Jan 1 1994, In : Neoplasma. 41, 3, p. 151-157 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
15 Scopus citations
1991

Purification and functional characterization of MerD: A coregulator of the mercury resistance operon in gram-negative bacteria

Mukhopadhyay, D., Yu, H., Nucifora, G. & Misra, T. K., Oct 5 1991, In : Journal of Biological Chemistry. 266, 28, p. 18538-18542 5 p.

Research output: Contribution to journalArticle

52 Scopus citations