Debabrata Mukhopadhyay, PhD

  • 14385 Citations
  • 60 Scopus h-Index
1991 …2020
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Research Output 1991 2019

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Article
2013
121 Citations (Scopus)

New insights into pancreatic cancer-induced paraneoplastic diabetes

Sah, R. P., Nagpal, S. J. S., Mukhopadhyay, D. & Chari, S. T., Jul 2013, In : Nature Reviews Gastroenterology and Hepatology. 10, 7, p. 423-433 11 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Type 2 Diabetes Mellitus
Weight Loss
Adrenomedullin
Cachexia
62 Citations (Scopus)

Plumbagin inhibits tumorigenesis and angiogenesis of ovarian cancer cells in vivo

Sinha, S., Pal, K., Elkhanany, A., Dutta, S., Cao, Y., Mondal, G., Iyer, S., Somasundaram, V., Couch, F. J., Shridhar, V., Bhattacharya, R., Mukhopadhyay, D. & Srinivas, P., Mar 1 2013, In : International Journal of Cancer. 132, 5, p. 1201-1212 12 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Carcinogenesis
Vascular Endothelial Growth Factor A
Cisplatin
Neoplasms
38 Citations (Scopus)

Simvastatin reduces venous stenosis formation in a murine hemodialysis vascular access model

Janardhanan, R., Yang, B., Vohra, P., Roy, B., Withers, S., Bhattacharya, S., Mandrekar, J., Kong, H., Leof, E. B., Mukhopadhyay, D. & Misra, S., Aug 2013, In : Kidney International. 84, 2, p. 338-352 15 p.

Research output: Contribution to journalArticle

Simvastatin
Matrix Metalloproteinase 9
Hyperplasia
Blood Vessels
Renal Dialysis
2012
82 Citations (Scopus)

Adrenomedullin is up-regulated in patients with pancreatic cancer and causes insulin resistance in β cells and mice

Aggarwal, G., Ramachandran, V., Javeed, N., Arumugam, T., Dutta, S., Klee, G. G., Klee, E. W., Smyrk, T. C., Bamlet, W., Han, J. J., Rumie Vittar, N. B., De Andrade, M., Mukhopadhyay, D., Petersen, G. M., Fernandez-Zapico, M. E., Logsdon, C. D. & Chari, S. T., Dec 2012, In : Gastroenterology. 143, 6

Research output: Contribution to journalArticle

Adrenomedullin
Pancreatic Neoplasms
Insulin Resistance
Cell Line
Insulin
22 Citations (Scopus)

Chemically modified peptides targeting the PDZ domain of GIPC as a therapeutic approach for cancer

Patra, C. R., Rupasinghe, C. N., Dutta, S. K., Bhattacharya, S., Wang, E., Spaller, M. R. & Mukhopadhyay, D., Apr 20 2012, In : ACS Chemical Biology. 7, 4, p. 770-779 10 p.

Research output: Contribution to journalArticle

PDZ Domains
Protein C
Peptides
Pancreatic Neoplasms
Neoplasms
38 Citations (Scopus)

DNA conjugated SWCNTs enter endothelial cells via Rac1 mediated macropinocytosis

Bhattacharya, S., Roxbury, D., Gong, X., Mukhopadhyay, D. & Jagota, A., Apr 11 2012, In : Nano Letters. 12, 4, p. 1826-1830 5 p.

Research output: Contribution to journalArticle

Endothelial cells
Single-walled carbon nanotubes (SWCN)
DNA
deoxyribonucleic acid
carbon nanotubes
18 Citations (Scopus)

Dopamine inhibits pulmonary edema through the VEGF-VEGFR2 axis in a murine model of acute lung injury

Vohra, P. K., Hoeppner, L. H., Sagar, G., Dutta, S. K., Misra, S., Hubmayr, R. D. & Mukhopadhyay, D., Jan 2012, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 302, 2, p. 185-192 8 p.

Research output: Contribution to journalArticle

Acute Lung Injury
Pulmonary Edema
Vascular Endothelial Growth Factor A
Dopamine
Capillary Permeability
24 Citations (Scopus)

Endogenous vascular endothelial growth factor-A (VEGF-A) maintains endothelial cell homeostasis by regulating VEGF receptor-2 transcription

E, G., Cao, Y., Bhattacharya, S., Dutta, S., Wang, E. & Mukhopadhyay, D., Jan 27 2012, In : Journal of Biological Chemistry. 287, 5, p. 3029-3041 13 p.

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor Receptor
Endothelial cells
Transcription
Vascular Endothelial Growth Factor A
Homeostasis
7 Citations (Scopus)

Nanomedicine: Pharmacological perspectives

Bhattacharya, S., Alkharfy, K. M., Janardhanan, R. & Mukhopadhyay, D., Jun 1 2012, In : Nanotechnology Reviews. 1, 3, p. 235-253 19 p.

Research output: Contribution to journalArticle

Pharmacodynamics
Nanomedicine
Medical nanotechnology
Precision Medicine
Nanotechnology
74 Citations (Scopus)

Neuropilin-1 stimulates tumor growth by increasing fibronectin fibril assembly in the tumor microenvironment

Yaqoob, U., Cao, S., Shergill, U., Jagavelu, K., Geng, Z., Yin, M., De Assuncao, T. M., Cao, Y., Szabolcs, A., Thorgeirsson, S., Schwartz, M., Yang, J. D., Ehman, R. L., Roberts, L. R., Mukhopadhyay, D. & Shah, V., Aug 15 2012, In : Cancer Research. 72, 16, p. 4047-4059 13 p.

Research output: Contribution to journalArticle

Neuropilin-1
Tumor Microenvironment
Fibronectins
Myofibroblasts
Growth
7 Citations (Scopus)

NHERF-2 maintains endothelial homeostasis

Bhattacharya, R., Wang, E., Dutta, S. K., Vohra, P. K., Guangqi, E., Prakash, Y. S. & Mukhopadhyay, D., May 17 2012, In : Blood. 119, 20, p. 4798-4806 9 p.

Research output: Contribution to journalArticle

Homeostasis
Endothelial cells
Endothelial Cells
Cyclin D1
Hemangioma
1010 Citations (Scopus)

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

Biankin, A. V., Waddell, N., Kassahn, K. S., Gingras, M. C., Muthuswamy, L. B., Johns, A. L., Miller, D. K., Wilson, P. J., Patch, A. M., Wu, J., Chang, D. K., Cowley, M. J., Gardiner, B. B., Song, S., Harliwong, I., Idrisoglu, S., Nourse, C., Nourbakhsh, E., Manning, S., Wani, S. & 106 others, Gongora, M., Pajic, M., Scarlett, C. J., Gill, A. J., Pinho, A. V., Rooman, I., Anderson, M., Holmes, O., Leonard, C., Taylor, D., Wood, S., Xu, Q., Nones, K., Fink, J. L., Christ, A., Bruxner, T., Cloonan, N., Kolle, G., Newell, F., Pinese, M., Mead, R. S., Humphris, J. L., Kaplan, W., Jones, M. D., Colvin, E. K., Nagrial, A. M., Humphrey, E. S., Chou, A., Chin, V. T., Chantrill, L. A., Mawson, A., Samra, J. S., Kench, J. G., Lovell, J. A., Daly, R. J., Merrett, N. D., Toon, C., Epari, K., Nguyen, N. Q., Barbour, A., Zeps, N., Kakkar, N., Zhao, F., Wu, Y. Q., Wang, M., Muzny, D. M., Fisher, W. E., Brunicardi, F. C., Hodges, S. E., Reid, J. G., Drummond, J., Chang, K., Han, Y., Lewis, L. R., Dinh, H., Buhay, C. J., Beck, T., Timms, L., Sam, M., Begley, K., Brown, A., Pai, D., Panchal, A., Buchner, N., De Borja, R., Denroche, R. E., Yung, C. K., Serra, S., Onetto, N., Mukhopadhyay, D., Tsao, M. S., Shaw, P. A., Petersen, G. M., Gallinger, S., Hruban, R. H., Maitra, A., Iacobuzio-Donahue, C. A., Schulick, R. D., Wolfgang, C. L., Morgan, R. A., Lawlor, R. T., Capelli, P., Corbo, V., Scardoni, M., Tortora, G., Tempero, M. A., Mann, K. M., Jenkins, N. A., Perez-Mancera, P. A., Adams, D. J., Largaespada, D. A., Wessels, L. F. A., Rust, A. G., Stein, L. D., Tuveson, D. A., Copeland, N. G., Musgrove, E. A., Scarpa, A., Eshleman, J. R., Hudson, T. J., Sutherland, R. L., Wheeler, D. A., Pearson, J. V., McPherson, J. D., Gibbs, R. A. & Grimmond, S. M., Nov 15 2012, In : Nature. 491, 7424, p. 399-405 7 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Genome
Genes
Carcinogenesis
Adenocarcinoma
16 Citations (Scopus)

Revealing the role of phospholipase Cβ3 in the regulation of VEGF-induced vascular permeability

Hoeppner, L. H., Phoenix, K. N., Clark, K. J., Bhattacharya, R., Gong, X., Sciuto, T. E., Vohra, P., Suresh, S., Bhattacharya, S., Dvorak, A. M., Ekker, S. C., Dvorak, H. F., Claffey, K. P. & Mukhopadhyay, D., Sep 13 2012, In : Blood. 120, 11, p. 2167-2173 7 p.

Research output: Contribution to journalArticle

Phospholipases
Capillary Permeability
Vascular Endothelial Growth Factor A
Zebrafish
Morpholinos
12 Citations (Scopus)

Tissue factor pathway inhibitor blocks angiogenesis via its carboxyl terminus

Holroyd, E. W., Delacroix, S., Larsen, K., Harbuzariu, A., Psaltis, P. J., Wang, L., Pan, S., White, T. A., Witt, T. A., Kleppe, L. S., Mueske, C. S., Mukhopadhyay, D. & Simari, R. D., Mar 2012, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 32, 3, p. 704-711 8 p.

Research output: Contribution to journalArticle

Thromboplastin
Endothelial Cells
Vascular Endothelial Growth Factor Receptor-2
Hindlimb
lipoprotein-associated coagulation inhibitor
1 Citation (Scopus)

Tumor angiogenesis 2012

Dudek, A. Z., Gupta, K., Ramakrishnan, S. & Mukhopadhyay, D., 2012, In : Journal of Oncology. 857383.

Research output: Contribution to journalArticle

Neoplasms
26 Citations (Scopus)

Vaccines targeting tumor blood vessel antigens promote CD8 + T cell-dependent tumor eradication or dormancy in HLA-A2 transgenic mice

Zhao, X., Bose, A., Komita, H., Taylor, J. L., Chi, N., Lowe, D. B., Okada, H., Cao, Y., Mukhopadhyay, D., Cohen, P. A. & Storkus, W. J., Feb 15 2012, In : Journal of Immunology. 188, 4, p. 1782-1788 7 p.

Research output: Contribution to journalArticle

Vascular Tissue Neoplasms
CD8 Antigens
HLA-A2 Antigen
Transgenic Mice
Vaccines
80 Citations (Scopus)

VEGF exerts an angiogenesis-independent function in cancer cells to promote their malignant progression

Cao, Y., E, G., Wang, E., Pal, K., Dutta, S. K., Bar-Sagi, D. & Mukhopadhyay, D., Aug 15 2012, In : Cancer Research. 72, 16, p. 3912-3918 7 p.

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor A
Neuropilin-1
Neoplasms
Cell Dedifferentiation
Vascular Endothelial Growth Factor Receptor
2011
47 Citations (Scopus)

A functional family-wide screening of SP/KLF proteins identifies a subset of suppressors of KRAS-mediated cell growth

Fernandez-Zapico, M. E., Lomberk, G. A., Tsuji, S., DeMars, C. J., Bardsley, M. R., Lin, Y. H., Almada, L. L., Han, J. J., Mukhopadhyay, D., Ordog, T., Buttar, N. S. & Urrutia, R., Apr 15 2011, In : Biochemical Journal. 435, 2, p. 529-537 9 p.

Research output: Contribution to journalArticle

Cell growth
Screening
Growth
Proteins
Cyclin A
24 Citations (Scopus)

A lipid-modified estrogen derivative that treats breast cancer independent of estrogen receptor expression through simultaneous induction of autophagy and apoptosis

Sinha, S., Roy, S., Reddy, B. S., Pal, K., Sudhakar, G., Iyer, S., Dutta, S., Wang, E., Vohra, P. K., Roy, K. R., Reddanna, P., Mukhopadhyay, D. & Banerjee, R., Mar 2011, In : Molecular Cancer Research. 9, 3, p. 364-374 11 p.

Research output: Contribution to journalArticle

Autophagy
Estrogen Receptors
Estrogens
Apoptosis
Breast Neoplasms
17 Citations (Scopus)
Naphthoquinones
Cytotoxicity
Gold
Nanoparticles
Reactive Oxygen Species
43 Citations (Scopus)

Designing nanoconjugates to effectively target pancreatic cancer cells in vitro and in vivo

Khan, J. A., Kudgus, R. A., Szabolcs, A., Dutta, S., Wang, E., Cao, S., Curran, G. L., Shah, V., Curley, S., Mukhopadhyay, D., Robertson, J. D., Bhattacharya, R. & Mukherjee, P., 2011, In : PLoS One. 6, 6, e20347.

Research output: Contribution to journalArticle

Nanoconjugates
pancreatic neoplasms
Pancreatic Neoplasms
Nanoparticles
nanoparticles
17 Citations (Scopus)

Effect of hyperglycemia on human monocyte activation

Nandy, D., Janardhanan, R., Mukhopadhyay, D. & Basu, A., Apr 2011, In : Journal of Investigative Medicine. 59, 4, p. 661-667 7 p.

Research output: Contribution to journalArticle

Hyperglycemia
Monocytes
Chemical activation
Glucose
Chemokines
16 Citations (Scopus)

Growth factor mediated signaling in pancreatic pathogenesis

Nandy, D. & Mukhopadhyay, D., Mar 2011, In : Cancers. 3, 1, p. 841-871 31 p.

Research output: Contribution to journalArticle

Pancreatitis
Intercellular Signaling Peptides and Proteins
Chronic Pancreatitis
Pancreatic Neoplasms
Neoplasms
20 Citations (Scopus)

Precise scheduling of chemotherapy primes VEGF-producing tumors for successful systemic oncolytic virotherapy

Kottke, T., Chester, J., Ilett, E., Thompson, J., Diaz, R., Coffey, M., Selby, P., Nuovo, G., Pulido, J. S., Mukhopadhyay, D., Pandha, H., Harrington, K., Melcher, A. & Vile, R. G., Oct 2011, In : Molecular Therapy. 19, 10, p. 1802-1812 11 p.

Research output: Contribution to journalArticle

Oncolytic Virotherapy
Vascular Endothelial Growth Factor A
Endothelial Cells
Paclitaxel
Drug Therapy
43 Citations (Scopus)

Reactive oxygen species driven angiogenesis by inorganic nanorods

Patra, C. R., Kim, J. H., Pramanik, K., D'Uscio, L. V., Patra, S., Pal, K., Ramchandran, R., Strano, M. S. & Mukhopadhyay, D., Nov 9 2011, In : Nano Letters. 11, 11, p. 4932-4938 7 p.

Research output: Contribution to journalArticle

angiogenesis
Nanorods
nanorods
Reactive Oxygen Species
Europium
50 Citations (Scopus)

Regulation of vascular endothelial growth factor receptor 2 trafficking and angiogenesis by Golgi localized t-SNARE syntaxin 6

Manickam, V., Tiwari, A., Jung, J. J., Bhattacharya, R., Goel, A., Mukhopadhyay, D. & Choudhury, A., Jan 27 2011, In : Blood. 117, 4, p. 1425-1435 11 p.

Research output: Contribution to journalArticle

Qa-SNARE Proteins
Vascular Endothelial Growth Factor Receptor-2
Ethylmaleimide
Membranes
Golgi Apparatus
43 Citations (Scopus)

Single-molecule detection of H2O2 mediating angiogenic redox signaling on fluorescent single-walled carbon nanotube array

Kim, J. H., Patra, C. R., Arkalgud, J. R., Boghossian, A. A., Zhang, J., Han, J. H., Reuel, N. F., Ahn, J. H., Mukhopadhyay, D. & Strano, M. S., Oct 25 2011, In : ACS Nano. 5, 10, p. 7848-7857 10 p.

Research output: Contribution to journalArticle

Endothelial cells
Single-walled carbon nanotubes (SWCN)
stimulation
veins
carbon nanotubes
17 Citations (Scopus)

Structure-activity study to develop cationic lipid-conjugated haloperidol derivatives as a new class of anticancer therapeutics

Pal, K., Pore, S., Sinha, S., Janardhanan, R., Mukhopadhyay, D. & Banerjee, R., Apr 14 2011, In : Journal of Medicinal Chemistry. 54, 7, p. 2378-2390 13 p.

Research output: Contribution to journalArticle

Haloperidol
Lipids
Apoptosis
Therapeutics
Neoplasms
75 Citations (Scopus)

The novel receptor tyrosine kinase Axl is constitutively active in B-cell chronic lymphocytic leukemia and acts as a docking site of nonreceptor kinases: Implications for therapy

Ghosh, A. K., Secreto, C., Boysen, J., Sassoon, T., Shanafelt, T. D., Mukhopadhyay, D. & Kay, N. E., Feb 10 2011, In : Blood. 117, 6, p. 1928-1937 10 p.

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
Phosphotransferases
Cells
Therapeutics
src-Family Kinases
11 Citations (Scopus)

Von Hippel-Lindau gene product directs cytokinesis: A new tumor suppressor function

Sinha, S., Mondal, G., Hwang, E. J., Han, D. W., Dutta, S. K., Iyer, S., Karumanchi, S. A., Kim, K. I., Couch, F. J. & Mukhopadhyay, D., Jul 1 2011, In : Journal of Cell Science. 124, 13, p. 2132-2142 11 p.

Research output: Contribution to journalArticle

Cytokinesis
Renal Cell Carcinoma
Polyploidy
Genes
Lysine
2010
8 Citations (Scopus)

A core-shell nanomaterial with endogenous therapeutic and diagnostic functions

Patra, C. R., Jing, Y., Xu, Y. H., Bhattacharya, R., Mukhopadhyay, D., Glockner, J., Wang, J. P. & Mukherjee, P., Dec 2010, In : Cancer Nanotechnology. 1, 1-6, p. 13-18 6 p.

Research output: Contribution to journalArticle

Nanostructures
Nanostructured materials
Magnetic Resonance Imaging
Magnetic resonance
magnetic resonance
16 Citations (Scopus)
Medical problems
Type 2 Diabetes Mellitus
Vascular Endothelial Growth Factor A
Fasting
Glucose
146 Citations (Scopus)

Circulating microvesicles in B-cell chronic lymphocytic leukemia can stimulate marrow stromal cells: Implications for disease progression

Ghosh, A. K., Secreto, C. R., Knox, T. R., Ding, W. D., Mukhopadhyay, D. & Kay, N. E., Mar 4 2010, In : Blood. 115, 9, p. 1755-1764 10 p.

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
Stromal Cells
Disease Progression
Bone Marrow
Cells
22 Citations (Scopus)

Endothelial cell-specific chemotaxis receptor (ecscr) promotes angioblast migration during vasculogenesis and enhances VEGF receptor sensitivity

Verma, A., Bhattacharya, R., Remadevi, I., Li, K., Pramanik, K., Samant, G. V., Horswill, M., Chun, C. Z., Zhao, B., Wang, E., Miao, R. Q., Mukhopadhyay, D., Ramchandran, R. & Wilkinson, G. A., Jun 3 2010, In : Blood. 115, 22, p. 4614-4622 9 p.

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor Receptor
Growth Factor Receptors
Endothelial cells
Chemotaxis
Endothelial Cells
34 Citations (Scopus)
Ephrin-B2
Hepatic Stellate Cells
Vascular Endothelial Growth Factor A
Endothelial Cells
Chemotaxis

Erratum: Vascular endothelial growth factor and semaphorin induce neuropilin-1 endocytosis via separate pathways (Circulation Research (2008) 103 (e71-e79))

Salikhova, A., Wang, L., Lanahan, A. A., Liu, M., Simons, M., Leenders, W. P. J., Mukhopadhyay, D. & Horowitz, A., Oct 29 2010, In : Circulation Research. 107, 9

Research output: Contribution to journalArticle

Neuropilin-1
Semaphorins
Endocytosis
Vascular Endothelial Growth Factor A
Research
31 Citations (Scopus)

Fabrication and characterization of an inorganic gold and silica nanoparticle mediated drug delivery system for nitric oxide.

Das, A., Mukherjee, P., Singla, S. K., Guturu, P., Frost, M. C., Mukhopadhyay, D., Shah, V. & Patra, C. R., Jul 30 2010, In : Nanotechnology. 21, 30, p. 305102 1 p.

Research output: Contribution to journalArticle

Nanoconjugates
Nitric oxide
Silicon Dioxide
Gold
Nitric Oxide
269 Citations (Scopus)

Fabrication of gold nanoparticles for targeted therapy in pancreatic cancer

Patra, C. R., Bhattacharya, R., Mukhopadhyay, D. & Mukherjee, P., Mar 8 2010, In : Advanced Drug Delivery Reviews. 62, 3, p. 346-361 16 p.

Research output: Contribution to journalArticle

Nanotechnology
Pancreatic Neoplasms
Gold
Nanoparticles
Surface Plasmon Resonance
33 Citations (Scopus)
Tissue Inhibitor of Metalloproteinases
Myofibroblasts
Matrix Metalloproteinase 2
Hyperplasia
Renal Dialysis
1218 Citations (Scopus)

International network of cancer genome projects

Hudson, T. J., Anderson, W., Aretz, A., Barker, A. D., Bell, C., Bernabé, R. R., Bhan, M. K., Calvo, F., Eerola, I., Gerhard, D. S., Guttmacher, A., Guyer, M., Hemsley, F. M., Jennings, J. L., Kerr, D., Klatt, P., Kolar, P., Kusuda, J., Lane, D. P., Laplace, F. & 241 others, Lu, Y., Nettekoven, G., Ozenberger, B., Peterson, J., Rao, T. S., Remacle, J., Schafer, A. J., Shibata, T., Stratton, M. R., Vockley, J. G., Watanabe, K., Yang, H., Yuen, M. M. F., Knoppers, B. M., Bobrow, M., Cambon-Thomsen, A., Dressler, L. G., Dyke, S. O. M., Joly, Y., Kato, K., Kennedy, K. L., Nicolás, P., Parker, M. J., Rial-Sebbag, E., Romeo-Casabona, C. M., Shaw, K. M., Wallace, S., Wiesner, G. L., Zeps, N., Lichter, P., Biankin, A. V., Chabannon, C., Chin, L., Clément, B., Alava, E. D., Degos, F., Ferguson, M. L., Geary, P., Hayes, D. N., Johns, A. L., Kasprzyk, A., Nakagawa, H., Penny, R., Piris, M. A., Sarin, R., Scarpa, A., De Vijver, M. V., Futreal, P. A., Aburatani, H., Bayés, M., Bowtell, D. D. L., Campbel, P. J., Estivill, X., Grimmond, S. M., Gut, I., Hirst, M., López-Otý́n, C., Majumder, P., Marra, M., McPherson, J. D., Ning, Z., Puente, X. S., Ruan, Y., Stunnenberg, H. G., Swerdlow, H., Velculescu, V. E., Wilson, R. K., Xue, H. H., Yang, L., Spellman, P. T., Bader, G. D., Boutros, P. C., Flicek, P., Getz, G., Guigó, R., Guo, G., Haussler, D., Heath, S., Hubbard, T. J., Jiang, T., Jones, S. M., Li, Q., López-Bigas, N., Luo, R., Muthuswamy, L., Ouellette, B. F. F., Pearson, J. V., Quesada, V., Raphael, B. J., Sander, C., Speed, T. P., Stein, L. D., Stuart, J. M., Teague, J. W., Totoki, Y., Tsunoda, T., Valencia, A., Wheeler, D. A., Wu, H., Zhao, S., Zhou, G., Lathrop, M., Thomas, G., Yoshida, T., Axton, M., Gunter, C., Miller, L. J., Zhang, J., Haider, S. A., Wang, J., Yung, C. K., Cross, A., Liang, Y., Gnaneshan, S., Guberman, J., Hsu, J., Chalmers, D. R. C., Hasel, K. W., Kaan, T. S. H., Lowrance, W. W., Masui, T., Rodriguez, L. L., Vergely, C., Bowtel, D. D. L., Cloonan, N., DeFazio, A., Eshleman, J. R., Etemadmoghadam, D., Gardiner, B. A., Kench, J. G., Sutherland, R. L., Tempero, M. A., Waddell, N. J., Wilson, P. J., Gallinger, S., Tsao, M. S., Shaw, P. A., Petersen, G. M., Mukhopadhyay, D., DePinho, R. A., Thayer, S., Shazand, K., Beck, T., Sam, M., Timms, L., Ballin, V., Ji, J., Zhang, X., Chen, F., Hu, X., Yang, Q., Tian, G., Zhang, L., Xing, X., Li, X., Zhu, Z., Yu, Y., Yu, J., Tost, J., Brennan, P., Holcatova, I., Zaridze, D., Brazma, A., Egevad, L., Prokhortchouk, E., Banks, R. E., Uhlén, M., Viksna, J., Ponten, F., Skryabin, K., Futrea, P. A., Birney, E., Borg, A., Børresen-Dale, A. L., Caldas, C., Foekens, J. A., Martin, S., Reis-Filho, J. S., Richardson, A. L., Sotiriou, C., Veer, L. V. T., Birnbaum, D., Blanche, H., Boucher, P., Boyault, S., Masson-Jacquemier, J. D., Pauporté, I., Pivot, X., Vincent-Salomon, A., Tabone, E., Theillet, C., Treilleux, I., Bioulac-Sage, P., Decaens, T., OiseDegos, F., Franco, D., Gut, M., Samuel, D., Zucman-Rossi, J., Eils, R., Brors, B., Korbe, J. O., Korshunov, A., Landgraf, P., Lehrach, H., Pfister, S., Radlwimmer, B., Reifenberger, G., Taylor, M. D., Kalle, C. V., Majumder, P. P., Rao, T. S., Pederzoli, P., Lawlor, R. T., Delledonne, M., Bardelli, A., Gress, T., Klimstra, D., Zamboni, G., Nakamura, Y., Miyano, S., Fujimoto, A., Campo, E., Sanjosé, S. D., Montserrat, E., González-Dý́az, M., Jares, P., Himmelbaue, H., Bea, S., Aparicio, S., Easton, D. F., Collins, F. S., Compton, C. C., Lander, E. S., Burke, W., Green, A. R., Hamilton, S. R., Kallioniemi, O. P., Ley, T. J., Liu, E. T. & Wainwright, B. J., Apr 15 2010, In : Nature. 464, 7291, p. 993-998 6 p.

Research output: Contribution to journalArticle

Genome
Neoplasms
Epigenomics
Mutation
Therapeutics
53 Citations (Scopus)

Neuropilin-1 mediates divergent R-smad signaling and the myofibroblast phenotype

Cao, Y., Szabolcs, A., Dutta, S. K., Yaqoob, U., Jagavelu, K., Wang, L., Leof, E. B., Urrutia, R. A., Shah, V. & Mukhopadhyay, D., Oct 8 2010, In : Journal of Biological Chemistry. 285, 41, p. 31840-31848 9 p.

Research output: Contribution to journalArticle

Neuropilin-1
Myofibroblasts
Transforming Growth Factor beta
Phenotype
Fibroblasts
97 Citations (Scopus)

Neuropilin-1 promotes cirrhosis of the rodent and human liver by enhancing PDGF/TGF-β signaling in hepatic stellate cells

Cao, S., Yaqoob, U., Das, A., Shergill, U., Jagavelu, K., Huebert, R. C., Routray, C., Abdelmoneim, S., Vasdev, M., Leof, E. B., Charlton, M., Watts, R. J., Mukhopadhyay, D. & Shah, V., Jul 1 2010, In : Journal of Clinical Investigation. 120, 7, p. 2379-2394 16 p.

Research output: Contribution to journalArticle

Neuropilin-1
Hepatic Stellate Cells
Rodentia
Fibrosis
Liver Cirrhosis
29 Citations (Scopus)

Pancreatic stellate cell models for transcriptional studies of desmoplasia-associated genes

Mathison, A., Liebl, A., Bharucha, J., Mukhopadhyay, D., Lomberk, G., Shah, V. & Urrutia, R., Oct 2010, In : Pancreatology. 10, 4, p. 505-516 12 p.

Research output: Contribution to journalArticle

Pancreatic Stellate Cells
Genes
Cell Line
Co-Repressor Proteins
Pancreatic Diseases
13 Citations (Scopus)

RGS-GAIP-interacting protein controls breast cancer progression

Wang, L., Lau, J. S., Patra, C. R., Cao, Y., Bhattacharya, S., Dutta, S., Nandy, D., Wang, E., Rupasinghe, C. N., Vohra, P., Spaller, M. R. & Mukhopadhyay, D., Dec 2010, In : Molecular Cancer Research. 8, 12, p. 1591-1600 10 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Proteins
Cell Survival
Cell Proliferation
PDZ Domains
8 Citations (Scopus)
Glycogen Synthase Kinases
Type 2 Diabetes Mellitus
Monocytes
Glycogen Synthase Kinase 3
Platelet Activating Factor
21 Citations (Scopus)

Sclerostin binds and regulates the activity of cysteine-rich protein 61

Craig, T. A., Bhattacharya, R., Mukhopadhyay, D. & Kumar, R., Jan 29 2010, In : Biochemical and Biophysical Research Communications. 392, 1, p. 36-40 5 p.

Research output: Contribution to journalArticle

Cysteine-Rich Protein 61
Osteoblasts
Extracellular Matrix Proteins
Endothelial cells
Cell proliferation
8 Citations (Scopus)

Tumor angiogenesis

Dudek, A., Gupta, K., Ramakrishnan, S. & Mukhopadhyay, D., 2010, In : Journal of Oncology. 761671.

Research output: Contribution to journalArticle

Neoplasms
5 Citations (Scopus)

VEGF neutralizing antibody increases the therapeutic efficacy of vinorelbine for renal cell carcinoma

Sinha, S., Cao, Y., Dutta, S., Wang, E. & Mukhopadhyay, D., Mar 2010, In : Journal of Cellular and Molecular Medicine. 14, 3, p. 647-658 12 p.

Research output: Contribution to journalArticle

Neutralizing Antibodies
Renal Cell Carcinoma
Vascular Endothelial Growth Factor A
Neoplasms
Anti-Idiotypic Antibodies
2009
93 Citations (Scopus)

Aberrant regulation of pVHL levels by microRNA promotes the HIF/VEGF axis in CLL B cells

Ghosh, A. K., Shanafelt, T. D., Cimmino, A., Taccioli, C., Volinia, S., Liu, C. G., Calin, G. A., Croce, C. M., Chan, D. A., Giaccia, A. J., Secreto, C., Wellik, L. E., Lee, Y. K., Mukhopadhyay, D. & Kay, N. E., 2009, In : Blood. 113, 22, p. 5568-5574 7 p.

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
MicroRNAs
Vascular Endothelial Growth Factor A
Cells
RNA Polymerase II
20 Citations (Scopus)
Adventitia
Matrix Metalloproteinase 9
Renal Dialysis
Swine
Endothelial Cells