• 6311 Citations
  • 36 Scopus h-Index
1990 …2019
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Research Output 1990 2019

2019
2 Citations (Scopus)

5-year overall survival in patients with lung cancer eligible or ineligible for screening according to US Preventive Services Task Force criteria: a prospective, observational cohort study

Luo, Y. H., Luo, L., Wampfler, J. A., Wang, Y., Liu, D., Chen, Y. M., Adjei, A., Midthun, D. E. & Yang, P., Aug 1 2019, In : The Lancet Oncology. 20, 8, p. 1098-1108 11 p.

Research output: Contribution to journalArticle

Open Access
Advisory Committees
Observational Studies
Lung Neoplasms
Cohort Studies
Survival

Dysphonia Due to Vocal Cord Injury After Rigid Bronchoscopy: A Case Study With 1-Year Bronchoscopic Follow-up

Youssef, S. J., Orbelo, D. M., Sakata, K. K., Zimmermann, T. M., Pittelko, R. L., Nelson, D. R., Midthun, D. E., Edell, E. S. & Ekbom, D. C., Oct 1 2019, In : Journal of Bronchology and Interventional Pulmonology. 26, 4, p. E52-E55

Research output: Contribution to journalLetter

Dysphonia
Vocal Cords
Bronchoscopy
Wounds and Injuries
2 Citations (Scopus)

Frailty and clinical outcomes in chronic obstructive pulmonary disease

NETT Research Group, Feb 1 2019, In : Annals of the American Thoracic Society. 16, 2, p. 217-224 8 p.

Research output: Contribution to journalArticle

Chronic Obstructive Pulmonary Disease
Confidence Intervals
Emphysema
Forced Expiratory Volume
Phenotype
1 Citation (Scopus)

Predictors of Response to Endobronchial Coil Therapy in Patients With Advanced Emphysema

RENEW Study Group, May 1 2019, In : Chest. 155, 5, p. 928-937 10 p.

Research output: Contribution to journalArticle

Emphysema
Residual Volume
Therapeutics
Pneumonectomy
Radiology
2018
18 Citations (Scopus)
Proteomics
Biomarkers
Lung
Neoplasms
Multicenter Studies
10 Citations (Scopus)

Comparison of Programmed Death Ligand-1 Immunohistochemical Staining Between Endobronchial Ultrasound Transbronchial Needle Aspiration and Resected Lung Cancer Specimens

Sakata, K. K., Midthun, D. E., Mullon, J. J., Kern, R. M., Nelson, D. R., Edell, E., Schiavo, D. N., Jett, J. R. & Aubry, M. C., Oct 1 2018, In : Chest. 154, 4, p. 827-837 11 p.

Research output: Contribution to journalArticle

Needles
Lung Neoplasms
Staining and Labeling
Ligands
Sensitivity and Specificity

Creation of a Balloon-Expandable Bifurcated Covered Stent to Treat a Complex Left Anastomotic Stricture in a Lung Transplant Recipient

Kern, R., Sakata, K., Peters, S. G., Midthun, D. E., Mullon, J. & Edell, E., Jul 17 2018, (Accepted/In press) In : Respiration. p. 1-4 4 p.

Research output: Contribution to journalArticle

Stents
Pathologic Constriction
Lung
Bronchi
Ischemia

Cutting Balloon Dilation for Central Airway Stricture

Sakata, K. K. & Midthun, D. E., Jul 1 2018, In : Journal of Bronchology and Interventional Pulmonology. 25, 3, p. e29-e30

Research output: Contribution to journalLetter

Dilatation
Pathologic Constriction

Extracellular matrix fistula plug for repair of bronchopleural fistula

Sakata, K. K., Reisenauer, J. S., Kern, R. M., Midthun, D. E., Utz, J. P., Blackmon, S. H., Mullon, J. J. & Wigle, D. A., Jan 1 2018, In : Respiratory Medicine Case Reports. 25, p. 207-210 4 p.

Research output: Contribution to journalArticle

Fistula
Extracellular Matrix
Air
Rectal Diseases
Muscles
55 Citations (Scopus)

Lung cancer screening, version 3.2018

Wood, D. E., Kazerooni, E. A., Baum, S. L., Eapen, G. A., Ettinger, D. S., Hou, L., Jackman, D. M., Klippenstein, D., Kumar, R., Lackner, R. P., Leard, L. E., Lennes, I. T., Leung, A. N. C., Makani, S. S., Massion, P. P., Mazzone, P., Merritt, R. E., Meyers, B. F., Midthun, D. E., Pipavath, S. & 13 others, Pratt, C., Reddy, C., Reid, M. E., Rotter, A. J., Sachs, P. B., Schabath, M. B., Schiebler, M. L., Tong, B. C., Travis, W. D., Wei, B., Yang, S. C., Gregory, K. M. & Hughes, M., Apr 1 2018, In : JNCCN Journal of the National Comprehensive Cancer Network. 16, 4, p. 412-441 30 p.

Research output: Contribution to journalComment/debate

Early Detection of Cancer
Lung Neoplasms
Tomography
Medicare
Thorax

Paclitaxel-coated balloon dilation for central airway obstruction

Sakata, K. K., Nelson, D. R., Mullon, J. J., Midthun, D. E., Edell, E. & Kern, R. M., Jan 1 2018, In : Respiratory Medicine Case Reports. 24, p. 129-132 4 p.

Research output: Contribution to journalArticle

Airway Obstruction
Paclitaxel
Dilatation
Bronchoscopy
Pathologic Constriction
7 Citations (Scopus)

RNAseq analysis of bronchial epithelial cells to identify COPD-associated genes and SNPs

Yeo, J., Morales, D. A., Chen, T., Crawford, E. L., Zhang, X., Blomquist, T. M., Levin, A. M., Massion, P. P., Arenberg, D. A., Midthun, D. E., Mazzone, P. J., Nathan, S. D., Wainz, R. J., Nana-Sinkam, P., Willey, P. F. S., Arend, T. J., Padda, K., Qiu, S., Federov, A., Hernandez, D. A. R. & 5 others, Hammersley, J. R., Yoon, Y., Safi, F., Khuder, S. A. & Willey, J. C., Mar 5 2018, In : BMC Pulmonary Medicine. 18, 1, 42.

Research output: Contribution to journalArticle

Chronic Obstructive Pulmonary Disease
Single Nucleotide Polymorphism
Epithelial Cells
Genes
Genome-Wide Association Study
2017
4 Citations (Scopus)

An integrated digital/clinical approach to smoking cessation in lung cancer screening: Study protocol for a randomized controlled trial

Graham, A. L., Burke, M. V., Jacobs, M. A., Cha, S., Croghan, I. T., Schroeder, D. R., Moriarty, J. P., Borah, B. J., Rasmussen, D. F., Brookover, M. J., Suesse, D. B., Midthun, D. E. & Hays, J. T., Nov 28 2017, In : Trials. 18, 1, 568.

Research output: Contribution to journalArticle

Smoking Cessation
Early Detection of Cancer
Text Messaging
Lung Neoplasms
Randomized Controlled Trials
3 Citations (Scopus)

Bronchoscopic management of airway compression due to fibrosing mediastinitis

Kern, R., Peikert, T. D., Edell, E., Mullon, J., Midthun, D. E., Utz, J. P. & Maldonado, F., Aug 1 2017, In : Annals of the American Thoracic Society. 14, 8, p. 1353-1355 3 p.

Research output: Contribution to journalLetter

1 Citation (Scopus)

Endobronchial-Guided Vascularized Tissue Flaps for a Bronchopleural Fistula

Elswick, S. M., Sharaf, B., Hammoudeh, Z. S., Saeed, A. I., Edell, E., Midthun, D. E. & Blackmon, S. H., Jul 1 2017, In : Annals of Thoracic Surgery. 104, 1, p. e1-e3

Research output: Contribution to journalArticle

Fistula
Surgical Flaps
Empyema
Squamous Cell Carcinoma
Lung

Inaccuracies describing results of a lung cancer screening demonstration project

Humphrey, L. L., Deffebach, M. & Midthun, D. E., Sep 1 2017, In : JAMA Internal Medicine. 177, 9, p. 1396-1397 2 p.

Research output: Contribution to journalComment/debate

Early Detection of Cancer
Lung Neoplasms
6 Citations (Scopus)

Management of Multifocal Lung Cancer: Results of a Survey

Leventakos, K., Peikert, T. D., Midthun, D. E., Molina, J. R., Blackmon, S., Nichols, F. C., Garces, Y. I., Hallemeier, C., Murphy, S. J., Vasmatzis, G., Kratz, S. L., Holland, W. P., Thomas, C. F., Mullon, J. J., Shen, K. R., Cassivi, S. D., Marks, R. S., Aubry, M. C., Adjei, A., Yang, P. & 4 others, Allen, M. S., Edell, E., Wigle, D. A. & Mansfield, A., 2017, (Accepted/In press) In : Journal of Thoracic Oncology.

Research output: Contribution to journalArticle

Lung Neoplasms
Neoplasm Metastasis
Mediastinoscopy
Mediastinum
Bronchoscopy
1 Citation (Scopus)

Pulmonary Hemorrhage Treated with Oxidized Regenerated Cellulose

Sakata, K. K., Nelson, D. R. & Midthun, D. E., 2017, In : Journal of Bronchology and Interventional Pulmonology. 24, 3, p. e42-e44

Research output: Contribution to journalLetter

oxidized cellulose
Hemorrhage
Lung
8 Citations (Scopus)
Early Detection of Cancer
Lung Neoplasms
Decision Making
2016
13 Citations (Scopus)

A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia

Lam, S., Mandrekar, S. J., Gesthalter, Y., Allen Ziegler, K. L., Seisler, D. K., Midthun, D. E., Mao, J. T., Aubry, M. C., McWilliams, A., Sin, D. D., Shaipanich, T., Liu, G., Johnson, E., Bild, A., Lenburg, M. E., Ionescu, D. N., Mayo, J., Yi, J., Tazelaar, H., Harmsen, W. S. & 5 others, Smith, J., Spira, A. E., Beane, J., Limburg, P. J. & Szabo, E., Dec 1 2016, In : Cancer Prevention Research. 9, 12, p. 906-914 9 p.

Research output: Contribution to journalArticle

Inositol
Placebos
Bronchoalveolar Lavage Fluid
Bronchoscopy
Phosphatidylinositol 3-Kinases
17 Citations (Scopus)

Early detection of lung cancer

Midthun, D. E., 2016, In : F1000Research. 5, 739.

Research output: Contribution to journalReview article

Early Detection of Cancer
Lung Neoplasms
Screening
Tomography
Incidental Findings
113 Citations (Scopus)

Effect of endobronchial coils vs usual care on exercise tolerance in patients with severe emphysema: The renew randomized clinical trial

RENEW Study Research Group, May 24 2016, In : JAMA - Journal of the American Medical Association. 315, 20, p. 2178-2189 12 p.

Research output: Contribution to journalArticle

Exercise Tolerance
Emphysema
Randomized Controlled Trials
Lung
Safety

Incidental life-threatening diagnosis during endobronchial ultrasound bronchoscopy

Clay, R., Midthun, D. E., Mullon, J. J. & Saeed, A. I., Oct 1 2016, In : Journal of Bronchology and Interventional Pulmonology. 23, 4, p. 316-318 3 p.

Research output: Contribution to journalComment/debate

Interventional Ultrasonography
Incidental Findings
Bronchoscopy
Pulmonary Embolism
Pulmonary Artery
6 Citations (Scopus)

Lung cancer risk test trial: Study design, participant baseline characteristics, bronchoscopy safety, and establishment of a biospecimen repository

Crawford, E. L., Levin, A., Safi, F., Lu, M., Baugh, A., Zhang, X., Yeo, J., Khuder, S. A., Boulos, A. M., Nana-Sinkam, P., Massion, P. P., Arenberg, D. A., Midthun, D. E., Mazzone, P. J., Nathan, S. D., Wainz, R., Silvestri, G., Tita, J. & Willey, J. C., Jan 22 2016, In : BMC Pulmonary Medicine. 16, 1, 16.

Research output: Contribution to journalArticle

Bronchoscopy
Lung Neoplasms
Safety
Epithelial Cells
Smoking
3 Citations (Scopus)

Pulmonary Abscess as a Complication of Transbronchial Lung Cryobiopsy

Skalski, J. H., Kern, R. M., Midthun, D. E., Edell, E. & Maldonado, F., 2016, In : Journal of Bronchology and Interventional Pulmonology. 23, 1, p. 63-66 4 p.

Research output: Contribution to journalArticle

Lung Abscess
Lung
Biopsy
Interstitial Lung Diseases
Needle Biopsy
12 Citations (Scopus)

Trends in subpopulations at high risk for lung cancer

Yang, P., Wang, Y., Wampfler, J. A., Xie, D., Stoddard, S. M., She, J. & Midthun, D. E., 2016, In : Journal of Thoracic Oncology. 11, 2, p. 194-202 9 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Advisory Committees
Smoking
Community Hospital
Tobacco Products
2015
3 Citations (Scopus)

Acute bilateral pulmonary opacities associated with use of tocilizumab

Utz, J. P., Jinnur, P. K., Yi, E. S., Ryu, J. H., Midthun, D. E. & Davis, J. M. III., Oct 1 2015, In : Journal of Clinical Rheumatology. 21, 7, p. 382-385 4 p.

Research output: Contribution to journalArticle

Cogan Syndrome
Antibodies, Monoclonal, Humanized
Acute Lung Injury
Lung
tocilizumab
94 Citations (Scopus)

An official American Thoracic Society/American College of Chest Physicians policy statement: Implementation of low-dose computed tomography lung cancer screening programs in clinical practice

ATS/CHEST Committee on Low-Dose CT Lung Cancer Screening in Clinical Practice, Oct 1 2015, In : American Journal of Respiratory and Critical Care Medicine. 192, 7, p. 881-891 11 p.

Research output: Contribution to journalArticle

Early Detection of Cancer
Lung Neoplasms
Tomography
Radiation
Workflow
13 Citations (Scopus)

An Official American Thoracic Society research statement: A research framework for pulmonary nodule evaluation and management

ATS Ad Hoc Committee on Setting a Research Framework for Pulmonary Nodule Evaluation, Aug 15 2015, In : American Journal of Respiratory and Critical Care Medicine. 192, 4, p. 500-514 15 p.

Research output: Contribution to journalArticle

Lung
Research
Quality of Health Care
Registries
Research Personnel
2 Citations (Scopus)
Spontaneous Neoplasm Regression
Pleural Neoplasms
X Ray Computed Tomography
Joint Diseases
Mesothelioma
19 Citations (Scopus)

Trends in the proportion of patients with lung cancer meeting screening criteria

Wang, Y., Midthun, D. E., Wampfler, J. A., Deng, B., Stoddard, S. M., Zhang, S. & Yang, P., Feb 24 2015, In : JAMA - Journal of the American Medical Association. 313, 8, p. 853-855 3 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Validation of a multiprotein plasma classifier to identify benign lung nodules

Vachani, A., Pass, H. I., Rom, W. N., Midthun, D. E., Edell, E., Laviolette, M., Li, X. J., Fong, P. Y., Hunsucker, S. W., Hayward, C., Mazzone, P. J., Madtes, D. K., Miller, Y. E., Walker, M. G., Shi, J., Kearney, P., Fang, K. C. & Massion, P. P., Apr 30 2015, In : Journal of Thoracic Oncology. 10, 4, p. 629-637 9 p.

Research output: Contribution to journalArticle

Lung
Sensitivity and Specificity
Tobacco Use
Non-Small Cell Lung Carcinoma
Proteomics
2014
5 Citations (Scopus)

A distal airway foreign body removed with electromagnetic navigation bronchoscopy

Karpman, C., Midthun, D. E. & Mullon, J. J., 2014, In : Journal of Bronchology and Interventional Pulmonology. 21, 2, p. 170-172 3 p.

Research output: Contribution to journalArticle

Electromagnetic Phenomena
Bronchoscopy
Foreign Bodies
Bronchoscopes
Thoracic Surgery
1 Citation (Scopus)

Vanishing lung syndrome (idiopathic giant bullous emphysema)

Liang, J. J., Wigle, D. A. & Midthun, D. E., 2014, In : American Journal of the Medical Sciences. 348, 5, p. 440 1 p.

Research output: Contribution to journalArticle

Pulmonary Emphysema
Emphysema
Blister
Lung
2013
3 Citations (Scopus)

Cancer in pulmonary nodules detected on first screening CT

Maldonado, F., Peikert, T. D. & Midthun, D. E., 2013, In : New England Journal of Medicine. 369, 21, p. 2060 1 p.

Research output: Contribution to journalArticle

Solitary Pulmonary Nodule
Lung Neoplasms
Lung
6 Citations (Scopus)

Early diagnosis of lung cancer

Midthun, D. E., Apr 2 2013, In : F1000Prime Reports. 5, 12.

Research output: Contribution to journalArticle

Early Detection of Cancer
Lung Neoplasms
Thorax
Tomography
Spiral Computed Tomography
507 Citations (Scopus)

Evaluation of individuals with pulmonary nodules: When is it lung cancer? Diagnosis and management of lung cancer, 3rd ed: American college of chest physicians evidence-based clinical practice guidelines

Gould, M. K., Donington, J., Lynch, W. R., Mazzone, P. J., Midthun, D. E., Naidich, D. P. & Wiener, R. S., May 2013, In : Chest. 143, 5 SUPPL

Research output: Contribution to journalArticle

Evidence-Based Practice
Practice Guidelines
Lung Neoplasms
Thorax
Physicians
3 Citations (Scopus)

Favorable stage distribution in the NELSON trial: Promise or hype?

Midthun, D. E. & Gould, M. K., Apr 15 2013, In : American Journal of Respiratory and Critical Care Medicine. 187, 8, p. 792-793 2 p.

Research output: Contribution to journalArticle

Early Detection of Cancer
Lung Neoplasms
Adenocarcinoma
Smoking
7 Citations (Scopus)

Postbronchoscopy pneumomediastinum and subcutaneous emphysema

Liang, J. J. & Midthun, D. E., 2013, In : Internal Medicine. 52, 4, p. 519-520 2 p.

Research output: Contribution to journalArticle

Subcutaneous Emphysema
Mediastinal Emphysema
Interstitial Lung Diseases
Bronchoscopy

Predictive accuracy of the Liverpool lung project risk model

Young, R. P., Hopkins, R. J. & Midthun, D. E., Apr 2 2013, In : Annals of Internal Medicine. 158, 7, p. 568 1 p.

Research output: Contribution to journalArticle

X Ray Computed Tomography
Statistical Models
Early Detection of Cancer
Lung Neoplasms
Lung
9 Citations (Scopus)

Randomized phase II trial of sulindac for lung cancer chemoprevention

Limburg, P. J., Mandrekar, S. J., Aubry, M. C., Ziegler, K. L. A., Zhang, J., Yi, J. E., Henry, M., Tazelaar, H. D., Lam, S., McWilliams, A., Midthun, D. E., Edell, E., Rickman, O. B., Mazzone, P., Tockman, M., Beamis, J. F., Lamb, C., Simoff, M., Loprinzi, C. L., Szabo, E. & 1 others, Jett, J., Mar 2013, In : Lung Cancer. 79, 3, p. 254-261 8 p.

Research output: Contribution to journalArticle

Sulindac
Chemoprevention
Lung Neoplasms
Placebos
Bronchoscopy
17 Citations (Scopus)

Screening for lung cancer: The US studies

Midthun, D. E. & Jett, J. R., Oct 2013, In : Journal of Surgical Oncology. 108, 5, p. 275-279 5 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Early Detection of Cancer
Spiral Computed Tomography
Sputum
Cell Biology
2012

Benign Lung Tumors

Midthun, D. E., Jul 2012, Clinical Respiratory Medicine: Fourth Edition. Elsevier Inc., p. 810-817 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Lung
Neoplasms
9 Citations (Scopus)

Computed tomographic screening for lung cancer

Young, R. P., Hopkins, R. J. & Midthun, D. E., Oct 3 2012, In : JAMA - Journal of the American Medical Association. 308, 13, p. 1320 1 p.

Research output: Contribution to journalArticle

X Ray Computed Tomography
Lung Neoplasms
9 Citations (Scopus)

Endobronchial ultrasound-guided transbronchial needle aspiration: Determinants of sampling adequacy

DePew, Z. S., Edell, E., Midthun, D. E., Mullon, J. J., Bungum, A. O., Decker, P. A. & Maldonado, F., Oct 2012, In : Journal of Bronchology and Interventional Pulmonology. 19, 4, p. 271-276 6 p.

Research output: Contribution to journalArticle

Needles
Conscious Sedation
Lymph Nodes
Pulmonary Medicine
Propofol
14 Citations (Scopus)

Genetic variants associated with the risk of chronic obstructive pulmonary disease with and without lung cancer

De Andrade, M., Li, Y., Marks, R. S., Deschamps, C., Scanlon, P. D., Olswold, C. L., Jiang, R., Swensen, S. J., Sun, Z. D., Cunningham, J. M., Wampfler, J. A., Limper, A. H., Midthun, D. E. & Yang, P., Mar 2012, In : Cancer Prevention Research. 5, 3, p. 365-373 9 p.

Research output: Contribution to journalArticle

Chronic Obstructive Pulmonary Disease
Lung Neoplasms
Single Nucleotide Polymorphism
Genes
DNA Repair
62 Citations (Scopus)

Quality of life and symptom burden among long-term lung cancer survivors

Yang, P., Cheville, A. L., Wampfler, J. A., Garces, Y. I., Jatoi, A., Clark, M. M., Cassivi, S. D., Midthun, D. E., Marks, R. S., Aubry, M. C., Okuno, S. H., Williams, B. A., Nichols, F. C., Trastek, V. F., Sugimura, H., Sarna, L., Allen, M. S., Deschamps, C. & Sloan, J. A., Jan 2012, In : Journal of Thoracic Oncology. 7, 1, p. 64-70 7 p.

Research output: Contribution to journalArticle

Survivors
Lung Neoplasms
Quality of Life
Appetite
Dyspnea
2011
55 Citations (Scopus)

Effect of emphysema on lung cancer risk in smokers: A computed tomography-based assessment

Li, Y., Swensen, S. J., Karabekmez, L. G., Marks, R. S., Stoddard, S. M., Jiang, R., Worra, J. B., Zhang, F., Midthun, D. E., De Andrade, M., Song, Y. & Yang, P., Jan 2011, In : Cancer Prevention Research. 4, 1, p. 43-50 8 p.

Research output: Contribution to journalArticle

Emphysema
Lung Neoplasms
Tomography
Logistic Models
Spiral Computed Tomography
57 Citations (Scopus)

Fibrosing mediastinitis: Clinical presentation, therapeutic outcomes, and adaptive immune response

Peikert, T. D., Colby, T. V., Midthun, D. E., Pairolero, P. C., Edell, E., Schroeder, D. R. & Specks, U., Nov 2011, In : Medicine. 90, 6, p. 412-423 12 p.

Research output: Contribution to journalArticle

Adaptive Immunity
Histoplasmosis
B-Lymphocytes
Therapeutics
Blood Vessels

Lung cancer: evolving concepts.

Midthun, D. E. & Molina, J. R., Feb 2011, In : Seminars in Respiratory and Critical Care Medicine. 32, 1, p. 1-2 2 p.

Research output: Contribution to journalArticle

Mass Screening
Lung Neoplasms
Smoking