• 32931 Citations
  • 86 Scopus h-Index
1982 …2020

Research output per year

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Research Output

2020

Minority-centric meta-analyses of blood lipid levels identify novel loci in the Population Architecture using Genomics and Epidemiology (PAGE) study

VA Million Veteran Program, Mar 1 2020, In : PLoS genetics. 16, 3, e1008684.

Research output: Contribution to journalArticle

Open Access

Penalized models for analysis of multiple mediators

Schaid, D. J. & Sinnwell, J. P., Jan 1 2020, (Accepted/In press) In : Genetic epidemiology.

Research output: Contribution to journalArticle

Predictive Utility of Polygenic Risk Scores for Coronary Heart Disease in Three Major Racial and Ethnic Groups

Dikilitas, O., Schaid, D. J., Kosel, M. L., Carroll, R. J., Chute, C. G., Denny, J. A., Fedotov, A., Feng, Q. P., Hakonarson, H., Jarvik, G. P., Lee, M. T. M., Pacheco, J. A., Rowley, R., Sleiman, P. M., Stein, C. M., Sturm, A. C., Wei, W. Q., Wiesner, G. L., Williams, M. S., Zhang, Y. & 2 others, Manolio, T. A. & Kullo, I. J., May 7 2020, In : American journal of human genetics. 106, 5, p. 707-716 10 p.

Research output: Contribution to journalArticle

2019

An expanded variant list and assembly annotation identifies multiple novel coding and noncoding genes for prostate cancer risk using a normal prostate tissue eQTL data set

DeRycke, M. S., Larson, M. C., Nair, A. A., McDonnell, S. K., French, A. J., Tillmans, L. S., Riska, S. M., Baheti, S., Fogarty, Z. C., Larson, N., O'Brien, D. R., Cheville, J., Wang, L., Schaid, D. J. & Thibodeau, S. N., Apr 1 2019, In : PloS one. 14, 4, e0214588.

Research output: Contribution to journalArticle

Open Access

A phenome-wide association study to discover pleiotropic effects of PCSK9, APOB, and LDLR

Safarova, M. S., Satterfield, B. A., Fan, X., Austin, E. E., Ye, Z., Bastarache, L., Zheng, N., Ritchie, M. D., Borthwick, K. M., Williams, M. S., Larson, E. B., Scrol, A., Jarvik, G. P., Crosslin, D. R., Leppig, K., Rasmussen-Torvik, L. J., Pendergrass, S. A., Sturm, A. C., Namjou, B., Shah, A. S. & 12 others, Carroll, R. J., Chung, W. K., Wei, W. Q., Feng, Q. P., Stein, C. M., Roden, D. M., Manolio, T. A., Schaid, D. J., Denny, J. C., Hebbring, S. J., de Andrade, M. & Kullo, I. J., Dec 1 2019, In : npj Genomic Medicine. 4, 1, 3.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

A review of kernel methods for genetic association studies

Larson, N. B., Chen, J. & Schaid, D. J., Jan 1 2019, (Accepted/In press) In : Genetic Epidemiology.

Research output: Contribution to journalArticle

2 Scopus citations

Atlas-CNV: a validated approach to call single-exon CNVs in the eMERGESeq gene panel

Chiang, T., Liu, X., Wu, T. J., Hu, J., Sedlazeck, F. J., White, S., Schaid, D., Andrade, M. D., Jarvik, G. P., Crosslin, D., Stanaway, I., Carrell, D. S., Connolly, J. J., Hakonarson, H., Groopman, E. E., Gharavi, A. G., Fedotov, A., Bi, W., Leduc, M. S., Murdock, D. R. & 10 others, Jiang, Y., Meng, L., Eng, C. M., Wen, S., Yang, Y., Muzny, D. M., Boerwinkle, E., Salerno, W., Venner, E. & Gibbs, R. A., Sep 1 2019, In : Genetics in Medicine. 21, 9, p. 2135-2144 10 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Correction to: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci (Nature Genetics, (2018), 50, 7, (928-936), 10.1038/s41588-018-0142-8)

Breast and Prostate Cancer Cohort Consortium (BPC3), The PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium, Cancer of the Prostate in Sweden (CAPS), Prostate Cancer Genome-wide Association Study of Uncommon Susceptibility Loci (PEGASUS), The Genetic Associations and Mechanisms in Oncology (GAME-ON)/Elucidating Loci Involved in Prostate Cancer Susceptibility (ELLIPSE) Consortium, The Profile Study, Australian Prostate Cancer BioResource (APCB), The IMPACT Study & Canary PASS Investigators, Feb 1 2019, In : Nature Genetics. 51, 2, 1 p.

Research output: Contribution to journalComment/debate

Current perspectives in assessing humoral immunity after measles vaccination

Haralambieva, I. H., Kennedy, R. B., Ovsyannikova, I. G., Schaid, D. J. & Poland, G. A., Jan 2 2019, In : Expert Review of Vaccines. 18, 1, p. 75-87 13 p.

Research output: Contribution to journalReview article

7 Scopus citations

Detecting potential pleiotropy across cardiovascular and neurological diseases using univariate, bivariate, and multivariate methods on 43,870 individuals from the eMERGE network

Zhang, X., Veturi, Y., Verma, S., Bone, W., Verma, A., Lucas, A., Hebbring, S., Denny, J. C., Stanaway, I. B., Jarvik, G. P., Crosslin, D., Larson, E. B., Rasmussen-Torvik, L., Pendergrass, S. A., Smoller, J. W., Hakonarson, H., Sleiman, P., Weng, C., Fasel, D., Wei, W. Q. & 4 others, Kullo, I., Schaid, D., Chung, W. K. & Ritchie, M. D., Jan 1 2019, In : Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. 24, p. 272-283 12 p.

Research output: Contribution to journalArticle

1 Scopus citations
1 Scopus citations

Familial recurrence risk with varying amount of family history

Schaid, D. J., McDonnell, S. K. & Thibodeau, S. N., Jan 1 2019, In : Genetic epidemiology.

Research output: Contribution to journalArticle

1 Scopus citations

Genetic predictors of chemotherapy-related amenorrhea in women with breast cancer

Ruddy, K. J., Schaid, D. J., Partridge, A. H., Larson, N. B., Batzler, A., Häberle, L., Dittrich, R., Widschwendter, P., Fink, V., Bauer, E., Schwitulla, J., Rübner, M., Ekici, A. B., Aivazova-Fuchs, V., Stewart, E. A., Beckmann, M. W., Ginsburg, E., Wang, L., Weinshilboum, R. M., Couch, F. J. & 4 others, Janni, W., Rack, B., Vachon, C. & Fasching, P. A., Jan 1 2019, (Accepted/In press) In : Fertility and Sterility.

Research output: Contribution to journalArticle

Genome analysis and pleiotropy assessment using causal networks with loss of function mutation and metabolomics

Yazdani, A., Yazdani, A., Elsea, S. H., Schaid, D. J., Kosorok, M. R., Dangol, G. & Samiei, A., May 21 2019, In : BMC genomics. 20, 1, 395.

Research output: Contribution to journalArticle

Open Access

Harmonizing Clinical Sequencing and Interpretation for the eMERGE III Network

the eMERGE Consortium, Sep 5 2019, In : American journal of human genetics. 105, 3, p. 588-605 18 p.

Research output: Contribution to journalArticle

3 Scopus citations

Multivariate generalized linear model for genetic pleiotropy

Schaid, D. J., Tong, X., Batzler, A., Sinnwell, J. P., Qing, J. & Biernacka, J. M., Jan 1 2019, In : Biostatistics (Oxford, England). 20, 1, p. 111-128 18 p.

Research output: Contribution to journalArticle

1 Scopus citations

Sex Differences in Older Adults' Immune Responses to Seasonal Influenza Vaccination

Voigt, E. A., Ovsyannikova, I. G., Kennedy, R. B., Grill, D. E., Goergen, K. M., Schaid, D. J. & Poland, G. A., Jan 1 2019, In : Frontiers in immunology. 10, 1 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Targeted Sequencing Study to Uncover Shared Genetic Susceptibility Between Peripheral Artery Disease and Coronary Heart Disease-Brief Report

Safarova, M. S., Fan, X., Austin, E. E., van Zuydam, N., Hopewell, J., Schaid, D. J. & Kullo, I. J., Jun 1 2019, In : Arteriosclerosis, thrombosis, and vascular biology. 39, 6, p. 1227-1233 7 p.

Research output: Contribution to journalArticle

Open Access
2018

A small-sample kernel association test for correlated data with application to microbiome association studies

Zhan, X., Xue, L., Zheng, H., Plantinga, A., Wu, M. C., Schaid, D. J., Zhao, N. & Chen, J., Jan 1 2018, (Accepted/In press) In : Genetic Epidemiology.

Research output: Contribution to journalArticle

8 Scopus citations

Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

Schumacher, F. R., Al Olama, A. A., Berndt, S. I., Benlloch, S., Ahmed, M., Saunders, E. J., Dadaev, T., Leongamornlert, D., Anokian, E., Cieza-Borrella, C., Goh, C., Brook, M. N., Sheng, X., Fachal, L., Dennis, J., Tyrer, J., Muir, K., Lophatananon, A., Stevens, V. L., Gapstur, S. M. & 167 others, Carter, B. D., Tangen, C. M., Goodman, P. J., Thompson, I. M., Batra, J., Chambers, S., Moya, L., Clements, J., Horvath, L., Tilley, W., Risbridger, G. P., Gronberg, H., Aly, M., Nordström, T., Pharoah, P., Pashayan, N., Schleutker, J., Tammela, T. L. J., Sipeky, C., Auvinen, A., Albanes, D., Weinstein, S., Wolk, A., Håkansson, N., West, C. M. L., Dunning, A. M., Burnet, N., Mucci, L. A., Giovannucci, E., Andriole, G. L., Cussenot, O., Cancel-Tassin, G., Koutros, S., Beane Freeman, L. E., Sorensen, K. D., Orntoft, T. F., Borre, M., Maehle, L., Grindedal, E. M., Neal, D. E., Donovan, J. L., Hamdy, F. C., Martin, R. M., Travis, R. C., Key, T. J., Hamilton, R. J., Fleshner, N. E., Finelli, A., Ingles, S. A., Stern, M. C., Rosenstein, B. S., Kerns, S. L., Ostrer, H., Lu, Y. J., Zhang, H. W., Feng, N., Mao, X., Guo, X., Wang, G., Sun, Z., Giles, G. G., Southey, M. C., MacInnis, R. J., Fitzgerald, L. M., Kibel, A. S., Drake, B. F., Vega, A., Gómez-Caamaño, A., Szulkin, R., Eklund, M., Kogevinas, M., Llorca, J., Castaño-Vinyals, G., Penney, K. L., Stampfer, M., Park, J. Y., Sellers, T. A., Lin, H. Y., Stanford, J. L., Cybulski, C., Wokolorczyk, D., Lubinski, J., Ostrander, E. A., Geybels, M. S., Nordestgaard, B. G., Nielsen, S. F., Weischer, M., Bisbjerg, R., Røder, M. A., Iversen, P., Brenner, H., Cuk, K., Holleczek, B., Maier, C., Luedeke, M., Schnoeller, T., Kim, J., Logothetis, C. J., John, E. M., Teixeira, M. R., Paulo, P., Cardoso, M., Neuhausen, S. L., Steele, L., Ding, Y. C., De Ruyck, K., De Meerleer, G., Ost, P., Razack, A., Lim, J., Teo, S. H., Lin, D. W., Newcomb, L. F., Lessel, D., Gamulin, M., Kulis, T., Kaneva, R., Usmani, N., Singhal, S., Slavov, C., Mitev, V., Parliament, M., Claessens, F., Joniau, S., Van Den Broeck, T., Larkin, S., Townsend, P. A., Aukim-Hastie, C., Dominguez, M. G., Castelao, J. E., Martinez, M. E., Roobol, M. J., Jenster, G., Van Schaik, R. H. N., Menegaux, F., Truong, T., Koudou, Y. A., Xu, J., Khaw, K. T., Cannon-Albright, L., Pandha, H., Michael, A., Thibodeau, S. N., McDonnell, S. K., Schaid, D. J., Lindstrom, S., Turman, C., Ma, J., Hunter, D. J., Riboli, E., Siddiq, A., Canzian, F., Kolonel, L. N., Le Marchand, L., Hoover, R. N., Machiela, M. J., Cui, Z., Kraft, P., Amos, C. I., Conti, D. V., Easton, D. F., Wiklund, F., Chanock, S. J., Henderson, B. E., Kote-Jarai, Z., Haiman, C. A. & Eeles, R. A., Jul 1 2018, In : Nature Genetics. 50, 7, p. 928-936 9 p.

Research output: Contribution to journalArticle

89 Scopus citations

Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants

Dadaev, T., Saunders, E. J., Newcombe, P. J., Anokian, E., Leongamornlert, D. A., Brook, M. N., Cieza-Borrella, C., Mijuskovic, M., Wakerell, S., Olama, A. A. A., Schumacher, F. R., Berndt, S. I., Benlloch, S., Ahmed, M., Goh, C., Sheng, X., Zhang, Z., Muir, K., Govindasami, K., Lophatananon, A. & 290 others, Stevens, V. L., Gapstur, S. M., Carter, B. D., Tangen, C. M., Goodman, P., Thompson, I. M., Batra, J., Chambers, S., Moya, L., Clements, J., Horvath, L., Tilley, W., Risbridger, G., Gronberg, H., Aly, M., Nordström, T., Pharoah, P., Pashayan, N., Schleutker, J., Tammela, T. L. J., Sipeky, C., Auvinen, A., Albanes, D., Weinstein, S., Wolk, A., Hakansson, N., West, C., Dunning, A. M., Burnet, N., Mucci, L., Giovannucci, E., Andriole, G., Cussenot, O., Cancel-Tassin, G., Koutros, S., Freeman, L. E. B., Sorensen, K. D., Orntoft, T. F., Borre, M., Maehle, L., Grindedal, E. M., Neal, D. E., Donovan, J. L., Hamdy, F. C., Martin, R. M., Travis, R. C., Key, T. J., Hamilton, R. J., Fleshner, N. E., Finelli, A., Ingles, S. A., Stern, M. C., Rosenstein, B., Kerns, S., Ostrer, H., Lu, Y. J., Zhang, H. W., Feng, N., Mao, X., Guo, X., Wang, G., Sun, Z., Giles, G. G., Southey, M. C., MacInnis, R. J., Fitzgerald, L. M., Kibel, A. S., Drake, B. F., Vega, A., Gómez-Caamaño, A., Fachal, L., Szulkin, R., Eklund, M., Kogevinas, M., Llorca, J., Castaño-Vinyals, G., Penney, K. L., Stampfer, M., Park, J. Y., Sellers, T. A., Lin, H. Y., Stanford, J. L., Cybulski, C., Wokolorczyk, D., Lubinski, J., Ostrander, E. A., Geybels, M. S., Nordestgaard, B. G., Nielsen, S. F., Weisher, M., Bisbjerg, R., Røder, M. A., Iversen, P., Brenner, H., Cuk, K., Holleczek, B., Maier, C., Luedeke, M., Schnoeller, T., Kim, J., Logothetis, C. J., John, E. M., Teixeira, M. R., Paulo, P., Cardoso, M., Neuhausen, S. L., Steele, L., Ding, Y. C., De Ruyck, K., De Meerleer, G., Ost, P., Razack, A., Lim, J., Teo, S. H., Lin, D. W., Newcomb, L. F., Lessel, D., Gamulin, M., Kulis, T., Kaneva, R., Usmani, N., Slavov, C., Mitev, V., Parliament, M., Singhal, S., Claessens, F., Joniau, S., Van Den Broeck, T., Larkin, S., Townsend, P. A., Aukim-Hastie, C., Gago-Dominguez, M., Castelao, J. E., Martinez, M. E., Roobol, M. J., Jenster, G., Van Schaik, R. H. N., Menegaux, F., Truong, T., Koudou, Y. A., Xu, J., Khaw, K. T., Cannon-Albright, L., Pandha, H., Michael, A., Kierzek, A., Thibodeau, S. N., McDonnell, S. K., Schaid, D. J., Lindstrom, S., Turman, C., Ma, J., Hunter, D. J., Riboli, E., Siddiq, A., Canzian, F., Kolonel, L. N., Le Marchand, L., Hoover, R. N., Machiela, M. J., Kraft, P., Cook, M., Thwaites, A., Guy, M., Whitmore, I., Morgan, A., Fisher, C., Hazel, S., Livni, N., Spurdle, A., Srinivasan, S., Kedda, M. A., Aitken, J., Gardiner, R., Hayes, V., Butler, L., Taylor, R., Yeadon, T., Eckert, A., Saunders, P., Haynes, A. M., Papargiris, M., Kujala, P., Talala, K., Murtola, T., Taari, K., Dearnaley, D., Barnett, G., Bentzen, S., Elliott, R., Ranu, H., Hicks, B., Vogt, A., Hutchinson, A., Cox, A., Davis, M., Brown, P., George, A., Marsden, G., Lane, A., Lewis, S. J., Berry, C., Kulkarni, G. S., Toi, A., Evans, A., Zlotta, A. R., Van Der Kwast, T. H., Imai, T., Saito, S., Marzec, J., Cao, G., Lin, J., Ling, J., Li, M., Zhao, S. C., Ren, G., Yu, Y., Wu, Y., Wu, J., Zhou, B., Zhang, Y., Li, J., He, W., Guo, J., Pedersen, J., Hopper, J. L., Milne, R., Klim, A., Carballo, A., Lobato-Busto, R., Peleteiro, P., Calvo, P., Aguado, M., Ruiz-Dominguez, J. M., Cecchini, L., Mengual, L., Alcaraz, A., Bustamante, M., Gracia-Lavedan, E., Dierssen-Sotos, T., Gomez-Acebo, I., Pow-Sang, J., Park, H., Zachariah, B., Kluzniak, W., Kolb, S., Klarskov, P., Stegmaier, C., Vogel, W., Herkommer, K., Bohnert, P., Maia, S., Silva, M. P., De Langhe, S., Thierens, H., Tan, M. H., Ong, A. T., Kastelan, Z., Popov, E., Kachakova, D., Mitkova, A., Vlahova, A., Dikov, T., Christova, S., Carracedo, A., Bangma, C., Schroder, F. H., Cenee, S., Tretarre, B., Rebillard, X., Mulot, C., Sanchez, M., Adolfsson, J., Stattin, P., Johansson, J. E., Cavalli-Bjoerkman, C., Karlsson, A., Broms, M., Wu, H., Tillmans, L., Riska, S., Freedman, M., Wiklund, F., Chanock, S., Henderson, B. E., Easton, D. F., Haiman, C. A., Eeles, R. A., Conti, D. V. & Kote-Jarai, Z., Dec 1 2018, In : Nature communications. 9, 1, 2256.

Research output: Contribution to journalArticle

20 Scopus citations

From genome-wide associations to candidate causal variants by statistical fine-mapping

Schaid, D. J., Chen, W. & Larson, N., Aug 1 2018, In : Nature Reviews Genetics. 19, 8, p. 491-504 14 p.

Research output: Contribution to journalReview article

74 Scopus citations

Germline variation at 8q24 and prostate cancer risk in men of European ancestry

The PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium, Dec 1 2018, In : Nature communications. 9, 1, 4616.

Research output: Contribution to journalArticle

6 Scopus citations

Polymorphisms in the wilms tumor gene are associated with interindividual variations in rubella virus-specific cellular immunity after measles-mumps-rubella II vaccination

Voigt, E. A., Haralambieva, I. H., Larrabee, B. L., Kennedy, R. B., Ovsyannikova, I. G., Schaid, D. J. & Poland, G. A., Feb 15 2018, In : Journal of Infectious Diseases. 217, 4, p. 560-566 7 p.

Research output: Contribution to journalArticle

4 Scopus citations
2017

A DAB2IP genotype: Sex interaction is associated with abdominal aortic aneurysm expansion

Ye, Z., Austin, E., Schaid, D. J., Bailey, K. R., Pellikka, P. & Kullo, I. J., Oct 1 2017, In : Journal of Investigative Medicine. 65, 7, p. 1077-1082 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

A large population-based association study between HLA and KIR genotypes and measles vaccine antibody responses

Ovsyannikova, I. G., Schaid, D. J., Larrabee, B. R., Haralambieva, I. H., Kennedy, R. B. & Poland, G. A., Feb 1 2017, In : PLoS One. 12, 2, e0171261.

Research output: Contribution to journalArticle

8 Scopus citations

Fast and robust adjustment of cell mixtures in epigenome-wide association studies with SmartSVA

Chen, J., Behnam, E., Huang, J., Moffatt, M. F., Schaid, D. J., Liang, L. & Lin, X., May 26 2017, In : BMC Genomics. 18, 1, 413.

Research output: Contribution to journalArticle

6 Scopus citations

Genome-wide associations of CD46 and IFI44L genetic variants with neutralizing antibody response to measles vaccine

Haralambieva, I. H., Ovsyannikova, I. G., Kennedy, R. B., Larrabee, B. R., Zimmermann, M. T., Grill, D. E., Schaid, D. J. & Poland, G. A., Apr 1 2017, In : Human Genetics. 136, 4, p. 421-435 15 p.

Research output: Contribution to journalArticle

11 Scopus citations

gsSKAT: Rapid gene set analysis and multiple testing correction for rare-variant association studies using weighted linear kernels

Larson, N., Mcdonnell, S., Cannon Albright, L., Teerlink, C., Stanford, J., Ostrander, E. A., Isaacs, W. B., Xu, J., Cooney, K. A., Lange, E., Schleutker, J., Carpten, J. D., Powell, I., Bailey-Wilson, J. E., Cussenot, O., Cancel-Tassin, G., Giles, G. G., Macinnis, R. J., Maier, C., Whittemore, A. S. & 12 others, Hsieh, C. L., Wiklund, F., Catolona, W. J., Foulkes, W., Mandal, D., Eeles, R., Kote-Jarai, Z., Ackerman, M. J., Olson, T. M., Klein, C. J., Thibodeau, S. N. & Schaid, D. J., 2017, (Accepted/In press) In : Genetic Epidemiology.

Research output: Contribution to journalArticle

2 Scopus citations

Heritability of vaccine-induced measles neutralizing antibody titers

Schaid, D. J., Haralambieva, I. H., Larrabee, B. R., Ovsyannikova, I. G., Kennedy, R. B. & Poland, G. A., Mar 7 2017, In : Vaccine. 35, 10, p. 1390-1394 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Immunoglobulin GM and KM genes and measles vaccine-induced humoral immunity

Ovsyannikova, I. G., Larrabee, B. R., Schaid, D. J. & Poland, G. A., 2017, (Accepted/In press) In : Vaccine.

Research output: Contribution to journalArticle

1 Scopus citations

Mapping Complex Traits in a Diversity Outbred F1 Mouse Population Identifies Germline Modifiers of Metastasis in Human Prostate Cancer

Winter, J. M., Gildea, D. E., Andreas, J. P., Gatti, D. M., Williams, K. A., Lee, M., Hu, Y., Zhang, S., Mullikin, J. C., Wolfsberg, T. G., McDonnell, S. K., Fogarty, Z. C., Larson, M. C., French, A. J., Schaid, D. J., Thibodeau, S. N., Churchill, G. A. & Crawford, N. P. S., Jan 25 2017, In : Cell Systems. 4, 1, p. 31-45.e6

Research output: Contribution to journalArticle

19 Scopus citations

Network-directed cis-mediator analysis of normal prostate tissue expression profiles reveals downstream regulatory associations of prostate cancer susceptibility loci

Larson, N., McDonnell, S. K., Fogarty, Z., Larson, M. C., Cheville, J., Riska, S., Baheti, S., Weber, A. M., Nair, A. A., Wang, L., O'Brien, D., Davila, J., Schaid, D. J. & Thibodeau, S. N., Oct 17 2017, In : Oncotarget. 8, 49, p. 85896-85908 13 p.

Research output: Contribution to journalArticle

Polygenic risk scores in familial Alzheimer disease

Tosto, G., Bird, T. D., Tsuang, D., Bennett, D. A., Boeve, B. F., Cruchaga, C., Faber, K., Foroud, T. M., Farlow, M., Goate, A. M., Bertlesen, S., Graff-Radford, N. R., Medrano, M., Lantigua, R., Manly, J., Ottman, R., Rosenberg, R., Schaid, D. J., Schupf, N., Stern, Y. & 2 others, Sweet, R. A. & Mayeux, R., Mar 21 2017, In : Neurology. 88, 12, p. 1180-1186 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

Whole exome sequencing in 75 high-risk families with validation and replication in independent case-control studies identifies TANGO2, OR5H14, and CHAD as new prostate cancer susceptibility genes

Karyadi, D. M., Geybels, M. S., Karlins, E., Decker, B., McIntosh, L., Hutchinson, A., Kolb, S., McDonnell, S. K., Hicks, B., Middha, S., FitzGerald, L. M., DeRycke, M. S., Yeager, M., Schaid, D. J., Chanock, S. J., Thibodeau, S. N., Berndt, S. I., Stanford, J. L. & Ostrander, E. A., Jan 1 2017, In : Oncotarget. 8, 1, p. 1495-1507 13 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations
2016

A multi-locus genetic risk score for abdominal aortic aneurysm

Ye, Z., Austin, E., Schaid, D. J. & Kullo, I. J., Mar 1 2016, In : Atherosclerosis. 246, p. 274-279 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation

Gusev, A., Shi, H., Kichaev, G., Pomerantz, M., Li, F., Long, H. W., Ingles, S. A., Kittles, R. A., Strom, S. S., Rybicki, B. A., Nemesure, B., Isaacs, W. B., Zheng, W., Pettaway, C. A., Yeboah, E. D., Tettey, Y., Biritwum, R. B., Adjei, A. A., Tay, E., Truelove, A. & 108 others, Niwa, S., Chokkalingam, A. P., John, E. M., Murphy, A. B., Signorello, L. B., Carpten, J., Leske, M. C., Wu, S. Y., Hennis, A. J. M., Neslund-Dudas, C., Hsing, A. W., Chu, L., Goodman, P. J., Klein, E. A., Witte, J. S., Casey, G., Kaggwa, S., Cook, M. B., Stram, D. O., Blot, W. J., Eeles, R. A., Easton, D., Kote-Jarai, Z., Al Olama, A. A., Benlloch, S., Muir, K., Giles, G. G., Southey, M. C., Fitzgerald, L. M., Gronberg, H., Wiklund, F., Aly, M., Henderson, B. E., Schleutker, J., Wahlfors, T., Tammela, T. L. J., Nordestgaard, B. G., Key, T. J., Travis, R. C., Neal, D. E., Donovan, J. L., Hamdy, F. C., Pharoah, P., Pashayan, N., Khaw, K. T., Stanford, J. L., Thibodeau, S. N., McDonnell, S. K., Schaid, D. J., Maier, C., Vogel, W., Luedeke, M., Herkommer, K., Kibel, A. S., Cybulski, C., Wokolorczyk, D., Kluzniak, W., Cannon-Albright, L., Teerlink, C., Brenner, H., Dieffenbach, A. K., Arndt, V., Park, J. Y., Sellers, T. A., Lin, H. Y., Slavov, C., Kaneva, R., Mitev, V., Batra, J., Spurdle, A., Clements, J. A., Teixeira, M. R., Pandha, H., Michael, A., Paulo, P., Maia, S., Kierzek, A., Conti, D. V., Albanes, D., Berg, C., Berndt, S. I., Campa, D., Crawford, E. D., Diver, W. R., Gapstur, S. M., Gaziano, J. M., Giovannucci, E., Hoover, R., Hunter, D. J., Johansson, M., Kraft, P., Le Marchand, L., Lindström, S., Navarro, C., Overvad, K., Riboli, E., Siddiq, A., Stevens, V. L., Trichopoulos, D., Vineis, P., Yeager, M., Trynka, G., Raychaudhuri, S., Schumacher, F. R., Price, A. L., Freedman, M. L., Haiman, C. A. & Pasaniuc, B., Apr 7 2016, In : Nature communications. 7, 10979.

Research output: Contribution to journalArticle

22 Scopus citations

Genetically defined race, but not sex, is associated with higher humoral and cellular immune responses to measles vaccination

Voigt, E. A., Ovsyannikova, I. G., Haralambieva, I. H., Kennedy, R. B., Larrabee, B. R., Schaid, D. J. & Poland, G. A., Sep 22 2016, In : Vaccine. 34, 41, p. 4913-4919 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Genome-wide association of familial prostate cancer cases identifies evidence for a rare segregating haplotype at 8q24.21

The PRACTICAL Consortium & International Consortium for Prostate Cancer Genetics, Aug 1 2016, In : Human genetics. 135, 8, p. 923-938 16 p.

Research output: Contribution to journalArticle

14 Scopus citations

Genome-wide meta-analyses of breast, ovarian, and prostate cancer association studies identify multiple new susceptibility loci shared by at least two cancer types

Kar, S. P., Beesley, J., Al Olama, A. A., Michailidou, K., Tyrer, J., Kote-Jarai, Z. A., Lawrenson, K., Lindstrom, S., Ramus, S. J., Thompson, D. J., Kibel, A. S., Dansonka-Mieszkowska, A., Michael, A., Dieffenbach, A. K., Gentry-Maharaj, A., Whittemore, A. S., Wolk, A., Monteiro, A., Peixoto, A., Kierzek, A. & 203 others, Cox, A., Rudolph, A., Gonzalez-Neira, A., Wu, A. H., Lindblom, A., Swerdlow, A., Ziogas, A., Ekici, A. B., Burwinkel, B., Karlan, B. Y., Nordestgaard, B. G., Blomqvist, C., Phelan, C., McLean, C., Pearce, C. L., Vachon, C., Cybulski, C., Slavov, C., Stegmaier, C., Maier, C., Ambrosone, C. B., Hogdall, C. K., Teerlink, C. C., Kang, D., Tessier, D. C., Schaid, D. J., Stram, D. O., Cramer, D. W., Neal, D. E., Eccles, D., Flesch-Janys, D., Velez Edwards, D. R., Wokozorczyk, D., Levine, D. A., Yannoukakos, D., Sawyer, E. J., Bandera, E. V., Poole, E. M., Goode, E. L., Khusnutdinova, E., Hogdall, E., Song, F., Bruinsma, F., Heitz, F., Modugno, F., Hamdy, F. C., Wiklund, F., Giles, G. G., Olsson, H., Wildiers, H., Ulmer, H. U., Pandha, H., Risch, H. A., Darabi, H., Salvesen, H. B., Nevanlinna, H., Gronberg, H., Brenner, H., Brauch, H., Anton-Culver, H., Song, H., Lim, H. Y., McNeish, I., Campbell, I., Vergote, I., Gronwald, J., Lubiński, J., Stanford, J. L., Benitez, J., Doherty, J. A., Permuth, J. B., Chang-Claude, J., Donovan, J. L., Dennis, J., Schildkraut, J. M., Schleutker, J., Hopper, J. L., Kupryjanczyk, J., Park, J. Y., Figueroa, J., Clements, J. A., Knight, J. A., Peto, J., Cunningham, J. M., Pow-Sang, J., Batra, J., Czene, K., Lu, K. H., Herkommer, K., Khaw, K. T., Matsuo, K., Muir, K., Offitt, K., Chen, K., Moysich, K. B., Aittomaki, K., Odunsi, K., Kiemeney, L. A., Massuger, L. F. A. G., Fitzgerald, L. M., Cook, L. S., Cannon-Albright, L., Hooning, M. J., Pike, M. C., Bolla, M. K., Luedeke, M., Teixeira, M. R., Goodman, M. T., Schmidt, M. K., Riggan, M., Aly, M., Rossing, M. A., Beckmann, M. W., Moisse, M., Sanderson, M., Southey, M. C., Jones, M., Lush, M., Hildebrandt, M. A. T., Hou, M. F., Schoemaker, M. J., Garcia-Closas, M., Bogdanova, N., Rahman, N., Le, N. D., Orr, N., Wentzensen, N., Pashayan, N., Peterlongo, P., Guenel, P., Brennan, P., Paulo, P., Webb, P. M., Broberg, P., Fasching, P. A., Devilee, P., Wang, Q., Cai, Q., Li, Q., Kaneva, R., Butzow, R., Kopperud, R. K., Schmutzler, R. K., Stephenson, R. A., Macinnis, R. J., Hoover, R. N., Winqvist, R., Ness, R., Milne, R. L., Travis, R. C., Benlloch, S., Olson, S. H., McDonnell, S. K., Tworoger, S. S., Maia, S., Berndt, S., Lee, S. C., Teo, S. H., Thibodeau, S. N., Bojesen, S. E., Gapstur, S. M., Kjar, S. K., Pejovic, T., Tammela, T. L. J., Dork, T., Bruning, T., Wahlfors, T., Key, T. J., Edwards, T. L., Menon, U., Hamann, U., Mitev, V., Kosma, V. M., Setiawan, V. W., Kristensen, V., Arndt, V., Vogel, W., Zheng, W., Sieh, W., Blot, W. J., Kluzniak, W., Shu, X. O., Gao, Y. T., Schumacher, F., Freedman, M. L., Berchuck, A., Dunning, A. M., Simard, J., Haiman, C. A., Spurdle, A., Sellers, T. A., Hunter, D. J., Henderson, B. E., Kraft, P., Chanock, S. J., Couch, F. J., Hall, P., Gayther, S. A., Easton, D. F., Chenevix-Trench, G., Eeles, R., Pharoah, P. D. P. & Lambrechts, D., Sep 1 2016, In : Cancer discovery. 6, 9, p. 1052-1067 16 p.

Research output: Contribution to journalArticle

64 Scopus citations

Incorporating a Genetic Risk Score into Coronary Heart Disease Risk Estimates: Effect on LDL Cholesterol Levels (the MIGENES Clinical Trial)

Kullo, I. J., Jouni, H., Austin, E. E., Brown, S. A., Kruisselbrink, T. M., Isseh, I. N., Haddad, R. A., Marroush, T. S., Shameer, K., Olson, J. E., Broeckel, U., Green, R. C., Schaid, D. J., Montori, V. M. & Bailey, K. R., Feb 26 2016, (Accepted/In press) In : Circulation.

Research output: Contribution to journalArticle

75 Scopus citations

Incorporating functional annotations for fine-mapping causal variants in a bayesian framework using summary statistics

Chen, W., McDonnell, S. K., Thibodeau, S. N., Tillmans, L. S. & Schaid, D. J., Nov 1 2016, In : Genetics. 204, 3, p. 933-958 26 p.

Research output: Contribution to journalArticle

15 Scopus citations

PALB2, CHEK2 and ATM rare variants and cancer risk: Data from COGS

kConFab Investigators66 & Australian Ovarian Cancer Study Group65,66, Dec 1 2016, In : Journal of medical genetics. 53, 12, p. 800-811 12 p.

Research output: Contribution to journalArticle

74 Scopus citations

Post hoc Analysis for Detecting Individual Rare Variant Risk Associations Using Probit Regression Bayesian Variable Selection Methods in Case-Control Sequencing Studies

Larson, N. B., McDonnell, S., Albright, L. C., Teerlink, C., Stanford, J., Ostrander, E. A., Isaacs, W. B., Xu, J., Cooney, K. A., Lange, E., Schleutker, J., Carpten, J. D., Powell, I., Bailey-Wilson, J., Cussenot, O., Cancel-Tassin, G., Giles, G., MacInnis, R., Maier, C., Whittemore, A. S. & 12 others, Hsieh, C. L., Wiklund, F., Catolona, W. J., Foulkes, W., Mandal, D., Eeles, R., Kote-Jarai, Z., Ackerman, M. J., Olson, T. M., Klein, C. J., Thibodeau, S. N. & Schaid, D. J., Sep 1 2016, In : Genetic epidemiology. 40, 6, p. 461-469 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Pubertal development and prostate cancer risk: Mendelian randomization study in a population-based cohort

The PRACTICAL Consortium, Jan 1 2016, In : BMC Medicine. 14, 1, 66.

Research output: Contribution to journalArticle

15 Scopus citations

REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants

Ioannidis, N. M., Rothstein, J. H., Pejaver, V., Middha, S., McDonnell, S. K., Baheti, S., Musolf, A., Li, Q., Holzinger, E., Karyadi, D., Cannon-Albright, L. A., Teerlink, C. C., Stanford, J. L., Isaacs, W. B., Xu, J., Cooney, K. A., Lange, E. M., Schleutker, J., Carpten, J. D., Powell, I. J. & 21 others, Cussenot, O., Cancel-Tassin, G., Giles, G. G., MacInnis, R. J., Maier, C., Hsieh, C. L., Wiklund, F., Catalona, W. J., Foulkes, W. D., Mandal, D., Eeles, R. A., Kote-Jarai, Z., Bustamante, C. D., Schaid, D. J., Hastie, T., Ostrander, E. A., Bailey-Wilson, J. E., Radivojac, P., Thibodeau, S. N., Whittemore, A. S. & Sieh, W., Oct 6 2016, In : American journal of human genetics. 99, 4, p. 877-885 9 p.

Research output: Contribution to journalArticle

245 Scopus citations

Small Sample Kernel Association Tests for Human Genetic and Microbiome Association Studies

Chen, J., Chen, W., Zhao, N., Wu, M. C. & Schaid, D. J., Jan 1 2016, In : Genetic Epidemiology. 40, 1, p. 5-19 15 p.

Research output: Contribution to journalArticle

20 Scopus citations

Statistical methods for testing genetic pleiotropy

Schaid, D. J., Tong, X., Larrabee, B., Kennedy, R. B., Poland, G. A. & Sinnwell, J. P., Oct 1 2016, In : Genetics. 204, 2, p. 483-497 15 p.

Research output: Contribution to journalArticle

19 Scopus citations

The role of cardiovascular risk factors and stroke in familial Alzheimer disease

Tosto, G., Bird, T. D., Bennett, D. A., Boeve, B. F., Brickman, A. M., Cruchaga, C., Faber, K., Foroud, T. M., Farlow, M., Goate, A. M., Graff Radford, N. R., Lantigua, R., Manly, J., Ottman, R., Rosenberg, R., Schaid, D. J., Schupf, N., Stern, Y., Sweet, R. A. & Mayeux, R., Oct 1 2016, In : JAMA Neurology. 73, 10, p. 1231-1237 7 p.

Research output: Contribution to journalArticle

23 Scopus citations
2015

A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences

Hoffmann, T. J., Van Den Eeden, S. K., Sakoda, L. C., Jorgenson, E., Habel, L. A., Graff, R. E., Passarelli, M. N., Cario, C. L., Emami, N. C., Chao, C. R., Ghai, N. R., Shan, J., Ranatunga, D. K., Quesenberry, C. P., Aaronson, D., Presti, J., Wang, Z., Berndt, S. I., Chanock, S. J., McDonnell, S. K. & 15 others, French, A. J., Schaid, D. J., Thibodeau, S. N., Li, Q., Freedman, M. L., Penney, K. L., Mucci, L. A., Haiman, C. A., Henderson, B. E., Seminara, D., Kvale, M. N., Kwok, P. Y., Schaefer, C., Risch, N. & Witte, J. S., Aug 1 2015, In : Cancer Discovery. 5, 8, p. 878-891 14 p.

Research output: Contribution to journalArticle

56 Scopus citations