Daniel D Billadeau, PhD

  • 9751 Citations
  • 59 Scopus h-Index
1990 …2021
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Research Output 1991 2019

  • 9751 Citations
  • 59 Scopus h-Index
  • 170 Article
  • 3 Chapter
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Article
2019

Glypican-1 and glycoprotein 2 bearing extracellular vesicles do not discern pancreatic cancer from benign pancreatic diseases

Lucien, F., Lac, V., Billadeau, D. D., Borgida, A., Gallinger, S. & Leong, H. S., Feb 1 2019, In : Oncotarget. 10, 10, p. 1045-1055 11 p.

Research output: Contribution to journalArticle

Glypicans
Pancreatic Diseases
Pancreatic Neoplasms
Glycoproteins
Adenocarcinoma

NKG2D-DAP10 signaling recruits EVL to the cytotoxic synapse to generate F-actin and promote NK cell cytotoxicity

Wilton, K. M., Overlee, B. L. & Billadeau, D. D., Jul 18 2019, In : Journal of cell science. 133, 5

Research output: Contribution to journalArticle

Open Access
Natural Killer Cells
Synapses
Actins
Integrins
NK Cell Lectin-Like Receptor Subfamily K
1 Citation (Scopus)

Targeting glycogen synthase kinase 3 for therapeutic benefit in lymphoma

Wu, X., Stenson, M., Abeykoon, J., Nowakowski, K., Zhang, L., Lawson, J., Wellik, L., Li, Y., Krull, J., Wenzl, K., Novak, A. J., Ansell, S. M., Bishop, G. A., Billadeau, D. D., Peng, K. W., Giles, F., Schmitt, D. M. & Witzig, T. E., Jul 25 2019, In : Blood. 134, 4, p. 363-373 11 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Lymphoma
Therapeutics
B-Lymphocytes
Clustered Regularly Interspaced Short Palindromic Repeats

The hepatic WASH complex is required for efficient plasma LDL and HDL cholesterol clearance

Wijers, M., Zanoni, P., Liv, N., Vos, D. Y., Jäckstein, M. Y., Smit, M., Wilbrink, S., Wolters, J. C., van der Veen, Y. T., Huijkman, N., Dekker, D., Kloosterhuis, N., van Dijk, T. H., Billadeau, D. D., Kuipers, F., Klumperman, J., von Eckardstein, A., Kuivenhoven, J. A. & van de Sluis, B., Jun 6 2019, In : JCI Insight. 4, 11, :e126462 .

Research output: Contribution to journalArticle

Open Access
Wiskott-Aldrich Syndrome Protein
LDL Cholesterol
HDL Cholesterol
LDL Receptors
Liver

WASH phosphorylation balances endosomal versus cortical actin network integrities during epithelial morphogenesis

Tsarouhas, V., Liu, D., Tsikala, G., Fedoseienko, A., Zinn, K., Matsuda, R., Billadeau, D. D. & Samakovlis, C., Dec 1 2019, In : Nature communications. 10, 1, 2193.

Research output: Contribution to journalArticle

Open Access
phosphorylation
Phosphorylation
Morphogenesis
integrity
Actins
1 Citation (Scopus)

WASH regulates glucose homeostasis by facilitating Glut2 receptor recycling in pancreatic β-cells

Ding, L., Han, L., Dube, J. & Billadeau, D. D., Feb 1 2019, In : Diabetes. 68, 2, p. 377-386 10 p.

Research output: Contribution to journalArticle

Homeostasis
Glucose
Pancreas
Wiskott-Aldrich Syndrome Protein
Actin-Related Protein 2-3 Complex

X-Linked Lymphoproliferative Syndrome Presenting as Adult-Onset Multi-Infarct Dementia

Blackburn, P. R., Lin, W. L., Miller, D. A., Lorenzo-Betancor, O., Edwards, E. S., Zimmermann, M. T., Farrugia, L. P., Freeman, W. D., Soto, A. I., Walton, R. L., Klee, E. W., Atwal, P. S., Abraham, R. S., Billadeau, D. D., Ross, O. A., Dickson, D. W. & Meschia, J. F., May 1 2019, In : Journal of neuropathology and experimental neurology. 78, 5, p. 460-466 7 p.

Research output: Contribution to journalArticle

Multi-Infarct Dementia
Lymphoproliferative Disorders
Siblings
Central Nervous System Vasculitis
Exome
2018
13 Citations (Scopus)

Endosomal receptor trafficking: Retromer and beyond

Wang, J., Fedoseienko, A., Chen, B., Burstein, E., Jia, D. & Billadeau, D. D., Jan 1 2018, (Accepted/In press) In : Traffic.

Research output: Contribution to journalArticle

Sorting Nexins
Endosomes
Pathogens
Sorting
Recycling

Epigenetics of gastrointestinal diseases: notes from a workshop

Marks, D. L., Olson, R. L., Urrutia, R., Billadeau, D. D., Roy, N., Calin, G. A., Fabbri, M., Koutsioumpa, M., Iliopoulos, D., Ordog, T., Huebert, R. C., Sarmento, O., Bamidele, A. O., Faubion, W. A., Lomberk, G. L., Siveke, J., Ahuja, N., Iovanna, J., Hlady, R. A., Robertson, K. D. & 3 others, Kisiel, J. B., Pin, C. L. & Fernandez-Zapico, M. E., Apr 3 2018, In : Epigenetics. 13, 4, p. 449-457 9 p.

Research output: Contribution to journalArticle

Gastrointestinal Diseases
Epigenomics
Education
DNA Methylation
Biomarkers
2 Citations (Scopus)

Microbial Sensing by Intestinal Myeloid Cells Controls Carcinogenesis and Epithelial Differentiation

Miyata, N., Morris, L. L., Chen, Q., Thorne, C., Singla, A., Zhu, W., Winter, M., Melton, S. D., Li, H., Sifuentes-Dominguez, L., Llano, E., Huff-Hardy, K., Starokadomskyy, P., Lopez, A., Reese, T. A., Turer, E., Billadeau, D. D., Winter, S. E. & Burstein, E., Aug 28 2018, In : Cell Reports. 24, 9, p. 2342-2355 14 p.

Research output: Contribution to journalArticle

Myeloid Cells
Prostaglandins
Goblet Cells
Carcinogenesis
Mucous Membrane
10 Citations (Scopus)

The COMMD family regulates plasma LDL levels and attenuates atherosclerosis through stabilizing the CCC complex in endosomal LDLR traffcking

Fedoseienko, A., Wijers, M., Wolters, J. C., Dekker, D., Smit, M., Huijkman, N., Kloosterhuis, N., Klug, H., Schepers, A., Van Dijk, K. W., Levels, J. H. M., Billadeau, D. D., Hofker, M. H., Van Deursen, J., Westerterp, M., Burstein, E., Kuivenhoven, J. A. & Van De Sluis, B., Jan 1 2018, In : Circulation Research. 122, 12, p. 1648-1660 13 p.

Research output: Contribution to journalArticle

LDL Receptors
Copper
Atherosclerosis
Liver
LDL Cholesterol

VASP Regulates NK Cell Lytic Granule Convergence

Wilton, K. M. & Billadeau, D. D., Nov 15 2018, In : Journal of Immunology. 201, 10, p. 2899-2909 11 p.

Research output: Contribution to journalArticle

Phosphoproteins
Natural Killer Cells
Microtubule-Organizing Center
Actins
Synapses
2017
35 Citations (Scopus)

Cellular functions of WASP family proteins at a glance

Alekhina, O., Burstein, E. & Billadeau, D. D., Jul 15 2017, In : Journal of Cell Science. 130, 14, p. 2235-2241 7 p.

Research output: Contribution to journalArticle

Wiskott-Aldrich Syndrome Protein Family
Pseudopodia
Actins
Actin-Related Protein 2-3 Complex
Posters
24 Citations (Scopus)

Fructose-1,6-bisphosphatase inhibits ERK activation and bypasses gemcitabine resistance in pancreatic cancer by blocking IQGAP1–MAPK interaction

Jin, X., Pan, Y., Wang, L., Ma, T., Zhang, L., Tang, A. H., Billadeau, D. D., Wu, H. & Huang, H., Aug 15 2017, In : Cancer Research. 77, 16, p. 4328-4341 14 p.

Research output: Contribution to journalArticle

gemcitabine
Fructose-Bisphosphatase
Pancreatic Neoplasms
Adenocarcinoma
Gluconeogenesis
3 Citations (Scopus)

Glycogen synthase kinase-3β ablation limits pancreatitis-induced acinar-to-ductal metaplasia

Ding, L., Liou, G. Y., Schmitt, D. M., Storz, P., Zhang, J. S. & Billadeau, D. D., Sep 1 2017, In : Journal of Pathology. 243, 1, p. 65-77 13 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Glycogen Synthase Kinases
Metaplasia
Pancreatitis
Ribosomal Protein S6 Kinases
9 Citations (Scopus)

Macrogenomic engineering via modulation of the scaling of chromatin packing density

Almassalha, L. M., Bauer, G. M., Wu, W., Cherkezyan, L., Zhang, D., Kendra, A., Gladstein, S., Chandler, J. E., Vanderway, D., Seagle, B. L. L., Ugolkov, A., Billadeau, D. D., O'Halloran, T. V., Mazar, A. P., Roy, H. K., Szleifer, I., Shahabi, S. & Backman, V., Nov 1 2017, In : Nature Biomedical Engineering. 1, 11, p. 902-913 12 p.

Research output: Contribution to journalArticle

Chromatin
Modulation
Genes
Cells
Gene expression
23 Citations (Scopus)

Molecular pathways: Revisiting glycogen synthase kinase-3β as a target for the treatment of cancer

Walz, A., Ugolkov, A., Chandra, S., Kozikowski, A., Carneiro, B. A., O'Halloran, T. V., Giles, F. J., Billadeau, D. D. & Mazar, A. P., Apr 15 2017, In : Clinical Cancer Research. 23, 8, p. 1891-1897 7 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Neoplasms
Protein-Serine-Threonine Kinases
Cell Nucleus
Type 2 Diabetes Mellitus
46 Citations (Scopus)

Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling

McNally, K. E., Faulkner, R., Steinberg, F., Gallon, M., Ghai, R., Pim, D., Langton, P., Pearson, N., Danson, C. M., Nägele, H., Morris, L. L., Singla, A., Overlee, B. L., Heesom, K. J., Sessions, R., Banks, L., Collins, B. M., Berger, I., Billadeau, D. D., Burstein, E. & 1 others, Cullen, P. J., Sep 29 2017, In : Nature Cell Biology. 19, 10, p. 1214-1225 12 p.

Research output: Contribution to journalArticle

Sorting Nexins
Multiprotein Complexes
Recycling
Integrins
Membrane Proteins
2016
34 Citations (Scopus)

CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL

Bartuzi, P., Billadeau, D. D., Favier, R., Rong, S., Dekker, D., Fedoseienko, A., Fieten, H., Wijers, M., Levels, J. H., Huijkman, N., Kloosterhuis, N., Van Der Molen, H., Brufau, G., Groen, A. K., Elliott, A. M., Kuivenhoven, J. A., Plecko, B., Grangl, G., McGaughran, J., Horton, J. D. & 3 others, Burstein, E., Hofker, M. H. & Van De Sluis, B., Mar 11 2016, In : Nature Communications. 7, 10961.

Research output: Contribution to journalArticle

Wiskott-Aldrich Syndrome Protein
lipoproteins
LDL Receptors
clearances
classifying
13 Citations (Scopus)

GSK-3 inhibition overcomes chemoresistance in human breast cancer

Ugolkov, A., Gaisina, I., Zhang, J. S., Billadeau, D. D., White, K., Kozikowski, A., Jain, S., Cristofanilli, M., Giles, F., O'Halloran, T., Cryns, V. L. & Mazar, A. P., Oct 1 2016, In : Cancer Letters. 380, 2, p. 384-392 9 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
irinotecan
Breast Neoplasms
Therapeutics
Protein-Serine-Threonine Kinases
9 Citations (Scopus)

GSK-3β governs inflammation-induced NFATc2 signaling hubs to promote pancreatic cancer progression

Baumgart, S., Chen, N. M., Zhang, J. S., Billadeau, D. D., Gaisina, I. N., Kozikowski, A. P., Singh, S. K., Fink, D., Ströbel, P., Klindt, C., Zhang, L., Bamlet, W. R., Koenig, A., Hessmann, E., Gress, T. M., Ellenrieder, V. & Neesse, A., Mar 1 2016, In : Molecular Cancer Therapeutics. 15, 3, p. 491-502 12 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Pancreatic Neoplasms
Inflammation
Growth
Cyclin-Dependent Kinase 6
15 Citations (Scopus)

Identification of HDAC6-Selective Inhibitors of Low Cancer Cell Cytotoxicity

Gaisina, I. N., Tueckmantel, W., Ugolkov, A., Shen, S., Hoffen, J., Dubrovskyi, O., Mazar, A., Schoon, R. A., Billadeau, D. D. & Kozikowski, A. P., Jan 5 2016, In : ChemMedChem. 11, 1, p. 81-92 12 p.

Research output: Contribution to journalArticle

Histone Deacetylases
Cytotoxicity
Cell growth
Cells
Isoxazoles
41 Citations (Scopus)

Integrated mate-pair and RNA sequencing identifies novel, targetable gene fusions in peripheral T-cell lymphoma

Luchtel, R., Razidlo, G., Dasari, S., Zeng, Y., Hu, G., Knudson, R. A., Greipp, P. T., Davila, J. I., Johnson, S. H., Porcher, J. C., Smadbeck, J., Eckloff, B. W., Billadeau, D. D., Kurtin, P. J., Mc Niven, M. A., Link, B. K., Ansell, S. M., Cerhan, J. R., Asmann, Y., Vasmatzis, G. & 1 others, Feldman, A. L., Sep 1 2016, In : Blood. 128, 9, p. 1234-1245 12 p.

Research output: Contribution to journalArticle

Peripheral T-Cell Lymphoma
RNA Sequence Analysis
T-cells
Gene Fusion
Fusion reactions
7 Citations (Scopus)

MMSET is dynamically regulated during cell-cycle progression and promotes normal DNA replication

Evans, D. L., Zhang, H., Ham, H., Pei, H., Lee, S. B., Kim, J. J., Billadeau, D. D. & Lou, Z., Jan 1 2016, In : Cell Cycle. 15, 1, p. 95-105 11 p.

Research output: Contribution to journalArticle

DNA Replication
Cell Cycle
Replication Origin
S Phase
Origin Recognition Complex
12 Citations (Scopus)

NFATc4 Regulates Sox9 gene expression in acinar cell plasticity and pancreatic cancer initiation

Hessmann, E., Zhang, J. S., Chen, N. M., Hasselluhn, M., Liou, G. Y., Storz, P., Ellenrieder, V., Billadeau, D. D. & Koenig, A., 2016, In : Stem Cells International. 2016, 5272498.

Research output: Contribution to journalArticle

Acinar Cells
Pancreatic Neoplasms
Epidermal Growth Factor
Gene Expression
Carcinogenesis
12 Citations (Scopus)

SIRT1-Activating compounds (STAC) negatively regulate pancreatic cancer cell growth and viability through a SIRT1 lysosomal-dependent pathway

Chini, C. C. S., Espindola-Netto, J. M., Mondal, G., Guerrico, A. M. G., Nin, V., Escande, C., Sola-Penna, M., Zhang, J. S., Billadeau, D. D. & Chini, E. N., May 15 2016, In : Clinical Cancer Research. 22, 10, p. 2496-2507 12 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Cell Survival
Growth
gemcitabine
Heterografts
24 Citations (Scopus)

Structural and mechanistic insights into regulation of the retromer coat by TBC1d5

Jia, D., Zhang, J. S., Li, F., Wang, J., Deng, Z., White, M. A., Osborne, D. G., Phillips-Krawczak, C., Gomez, T. S., Li, H., Singla, A., Burstein, E., Billadeau, D. D. & Rosen, M. K., Nov 9 2016, In : Nature Communications. 7, 13305.

Research output: Contribution to journalArticle

GTPase-Activating Proteins
proteins
Sorting Nexins
time measurement
membranes
2015
33 Citations (Scopus)

Antithetical NFATc1-Sox2 and p53-miR200 signaling networks govern pancreatic cancer cell plasticity

Singh, S. K., Chen, N. M., Hessmann, E., Siveke, J., Lahmann, M., Singh, G., Voelker, N., Vogt, S., Esposito, I., Schmidt, A., Brendel, C., Stiewe, T., Gaedcke, J., Mernberger, M., Crawford, H. C., Bamlet, W. R., Zhang, J. S., Li, X. K., Smyrk, T. C., Billadeau, D. D. & 4 others, Hebrok, M., Neesse, A., Koenig, A. & Ellenrieder, V., Feb 12 2015, In : EMBO Journal. 34, 4, p. 517-530 14 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Pancreatic Neoplasms
Plasticity
Adenocarcinoma
Cells
64 Citations (Scopus)

COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A

Phillips-Krawczak, C. A., Singla, A., Starokadomskyy, P., Deng, Z., Osborne, D. G., Li, H., Dick, C. J., Gomez, T. S., Koenecke, M., Zhang, J. S., Dai, H., Sifuentes-Dominguez, L. F., Geng, L. N., Kaufmann, S. H., Hein, M. Y., Wallis, M., McGaughran, J., Gecz, J., Van De Sluis, B., Billadeau, D. D. & 1 others, Burstein, E., Jan 1 2015, In : Molecular Biology of the Cell. 26, 1, p. 91-103 13 p.

Research output: Contribution to journalArticle

Copper
Endosomes
Homeostasis
Recycling
Actins
22 Citations (Scopus)

Endosomal sorting of notch receptors through COM MD9-dependent pathways modulates notch signaling

Li, H., Koo, Y., Mao, X., Sifuentes-Dominguez, L., Morris, L. L., Jia, D., Miyata, N., Faulkner, R. A., Van Deursen, J., Vooijs, M., Billadeau, D. D., Van de Sluis, B., Cleaver, O. & Burstein, E., Nov 1 2015, In : Journal of Cell Biology. 211, 3, p. 605-617 13 p.

Research output: Contribution to journalArticle

Notch Receptors
Copper
Recycling
Ligands
Genes
13 Citations (Scopus)

HKRP3 is a microtubule-binding protein regulating lytic granule clustering and NK cell killing

Ham, H., Huynh, W., Schoon, R. A., Vale, R. D. & Billadeau, D. D., Apr 15 2015, In : Journal of Immunology. 194, 8, p. 3984-3996 13 p.

Research output: Contribution to journalArticle

Microtubule Proteins
Natural Killer Cells
Cluster Analysis
Carrier Proteins
Microtubules
8 Citations (Scopus)

IQGAP1 promotes CXCR4 chemokine receptor function and trafficking via EEA-1+ endosomes

Bamidele, A. O., Kremer, K. N., Hirsova, P., Clift, I. C., Gores, G. J., Billadeau, D. D. & Hedin, K. E., 2015, In : Journal of Cell Biology. 210, 2, p. 257-272 16 p.

Research output: Contribution to journalArticle

CXCR4 Receptors
Chemokine Receptors
Endosomes
Recycling
Microtubule-Organizing Center

Neuronal and immune synapses on the move at traffic

Billadeau, D. D. & Faundez, V., Mar 1 2015, In : Traffic. 16, 3, p. 227-228 2 p.

Research output: Contribution to journalArticle

Animals
Antigen-Presenting Cells
26 Citations (Scopus)

NFATc1 links EGFR signaling to induction of sox9 transcription and acinar-ductal transdifferentiation in the pancreas

Chen, N. M., Singh, G., Koenig, A., Liou, G. Y., Storz, P., Zhang, J. S., Regul, L., Nagarajan, S., Kühnemuth, B., Johnsen, S. A., Hebrok, M., Siveke, J., Billadeau, D. D., Ellenrieder, V. & Hessmann, E., May 1 2015, In : Gastroenterology. 148, 5, p. 1024-1034.e9

Research output: Contribution to journalArticle

NFATC Transcription Factors
Epidermal Growth Factor Receptor
Pancreas
Acinar Cells
Pancreatic Neoplasms
11 Citations (Scopus)

Nuclear FAM21 participates in NF-κB-dependent gene regulation in pancreatic cancer cells

Deng, Z. H., Gomez, T. S., Osborne, D. G., Phillips-Krawczak, C. A., Zhang, J. S. & Billadeau, D. D., 2015, In : Journal of Cell Science. 128, 2, p. 373-384 12 p.

Research output: Contribution to journalArticle

gemcitabine
Pancreatic Neoplasms
Head
Nuclear Export Signals
Nuclear Localization Signals
26 Citations (Scopus)

Parkin Regulates Mitosis and Genomic Stability through Cdc20/Cdh1

Lee, S. B., Kim, J. J., Nam, H. J., Gao, B., Yin, P., Qin, B., Yi, S. Y., Ham, H., Evans, D., Kim, S. H., Zhang, J., Deng, M., Liu, T., Zhang, H., Billadeau, D. D., Wang, L. M., Giaime, E., Shen, J., Pang, Y-P., Jen, J. & 2 others, Van Deursen, J. & Lou, Z., Feb 19 2015, (Accepted/In press) In : Molecular Cell.

Research output: Contribution to journalArticle

Genomic Instability
Mitosis
Anaphase-Promoting Complex-Cyclosome
Ubiquitin-Protein Ligases
Carcinogenesis
13 Citations (Scopus)

SNX17 affects T cell activation by regulating TCR and integrin recycling

Osborne, D. G., Piotrowski, J. T., Dick, C. J., Zhang, J. S. & Billadeau, D. D., May 1 2015, In : Journal of Immunology. 194, 9, p. 4555-4566 12 p.

Research output: Contribution to journalArticle

Sorting Nexins
Recycling
Integrins
T-Lymphocytes
Lymphocyte Function-Associated Antigen-1
34 Citations (Scopus)

Vasodilator-stimulated phosphoprotein promotes activation of hepatic stellate cells by regulating Rab11-dependent plasma membrane targeting of transforming growth factor beta receptors

Tu, K., Li, J., Verma, V. K., Liu, C., Billadeau, D. D., Lamprecht, G., Xiang, X., Guo, L., Dhanasekaran, R., Roberts, L. R., Shah, V. & Kang, N., Jan 1 2015, In : Hepatology. 61, 1, p. 361-374 14 p.

Research output: Contribution to journalArticle

Transforming Growth Factor beta Receptors
Hepatic Stellate Cells
Cell Membrane
Transforming Growth Factor beta
Liver
2014
10 Citations (Scopus)

Coactosin-like 1 antagonizes cofilin to promote lamellipodial protrusion at the immune synapse

Kim, J., Shapiro, M. J., Bamidele, A. O., Gurel, P., Thapa, P., Higgs, H. N., Hedin, K. E., Shapiro, V. M. & Billadeau, D. D., Jan 13 2014, In : PLoS One. 9, 1, e85090.

Research output: Contribution to journalArticle

Cofilin 1
Actin Depolymerizing Factors
synapse
Synapses
actin
5 Citations (Scopus)

Dendritic cells utilize the evolutionarily conserved WASH and retromer complexes to promote MHCII recycling and helper T cell priming

Graham, D. B., Osborne, D. G., Piotrowski, J. T., Gomez, T. S., Gmyrek, G. B., Akilesh, H. M., Dani, A., Billadeau, D. D. & Swat, W., Jun 2 2014, In : PLoS One. 9, 6, e98606.

Research output: Contribution to journalArticle

T-cells
Recycling
dendritic cells
Helper-Inducer T-Lymphocytes
Dendritic Cells
29 Citations (Scopus)

Differential activity of GSK-3 isoforms regulates NF-κB and TRAIL- or TNFα induced apoptosis in pancreatic cancer cells

Zhang, J. S., Herreros-Vilanueva, M., Koenig, A., Deng, Z., De Narvajas, A. A. M., Gomez, T. S., Meng, X., Bujanda, L., Ellenrieder, V., Li, X. K., Kaufmann, S. H. & Billadeau, D. D., 2014, In : Cell Death and Disease. 5, 3, e1142.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Pancreatic Neoplasms
Protein Isoforms
Apoptosis
Adenocarcinoma
46 Citations (Scopus)

Embryonic stem cell factors and pancreatic cancer

Herreros-Villanueva, M., Bujanda, L., Billadeau, D. D. & Zhang, J. S., 2014, In : World Journal of Gastroenterology. 20, 9, p. 2247-2254 8 p.

Research output: Contribution to journalArticle

Stem Cell Factor
Embryonic Stem Cells
Pancreatic Neoplasms
Neoplastic Stem Cells
Adenocarcinoma

Erratum: Differential activity of GSK-3 isoforms regulates NF-κB and TRAIL- or TNFα induced apoptosis in pancreatic cancer cells (Cell Death and Disease (2014) 5 (e1142) DOI: 10.1038/cddis.2014.102)

Zhang, J. S., Herreros-Villanueva, M., Koenig, A., Deng, Z., De Narvajas, A. A. M., Gomez, T. S., Meng, X., Bujanda, L., Ellenrieder, V., Li, X. K., Kaufmann, S. H. & Billadeau, D. D., 2014, In : Cell Death and Disease. 5, 8, e1365.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Pancreatic Neoplasms
Protein Isoforms
Cell Death
Apoptosis
4 Citations (Scopus)

Erratum: Retromer Binding to FAM21 and the WASH Complex Is Perturbed by the Parkinson Disease-Linked VPS35(D620N) Mutation (Current Biology (2014) 24 (1670-1676))

McGough, I. J., Steinberg, F., Jia, D., Barbuti, P. A., McMillan, K. J., Heesom, K. J., Whone, A. L., Caldwell, M. A., Billadeau, D. D., Rosen, M. K. & Cullen, P. J., Jul 21 2014, In : Current Biology. 24, 14, p. 1678 1 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Human immunodeficiency syndromes affecting human natural killer cell cytolytic activity

Ham, H. & Billadeau, D. D., 2014, In : Frontiers in Immunology. 5, JAN, Article 2.

Research output: Contribution to journalArticle

Natural Killer Cells
Actins
Cell Membrane
Microtubule-Organizing Center
Microtubule Proteins
48 Citations (Scopus)

Inflammation-Induced NFATc1-STAT3 transcription complex promotes pancreatic cancer initiation by KrasG12D

Baumgart, S., Chen, N. M., Siveke, J. T., König, A., Zhang, J. S., Singh, S. K., Wolf, E., Bartkuhn, M., Esposito, I., Heßmann, E., Reinecke, J., Nikorowitsch, J., Brunner, M., Singh, G., Fernandez-Zapico, M. E., Smyrk, T. C., Bamlet, W. R., Eilers, M., Neesse, A., Gress, T. M. & 4 others, Billadeau, D. D., Tuveson, D., Urrutia, R. & Ellenrieder, V., 2014, In : Cancer Discovery. 4, 6, p. 688-701 14 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Carcinogenesis
Inflammation
STAT3 Transcription Factor
Neoplasms
20 Citations (Scopus)

Inhibition of gsk-3 induces differentiation and impaired glucose metabolism in renal cancer

Pal, K., Cao, Y., Gaisina, I. N., Bhattacharya, S., Dutta, S. K., Wang, E., Gunosewoyo, H., Kozikowski, A. P., Billadeau, D. D. & Mukhopadhyay, D., Feb 2014, In : Molecular Cancer Therapeutics. 13, 2, p. 285-296 12 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Kidney Neoplasms
Glucose
Renal Cell Carcinoma
Autophagy
19 Citations (Scopus)

Poly(ADP-ribose) polymerase inhibitors sensitize cancer cells to death receptor-mediated apoptosis by enhancing death receptor expression

Meng, X. W., Koh, B. D., Zhang, J. S., Flatten, K. S., Schneider, P. A., Billadeau, D. D., Hess, A. D., Smith, B. D., Karp, J. E. & Kaufmann, S. H., Jul 25 2014, In : Journal of Biological Chemistry. 289, 30, p. 20543-20558 16 p.

Research output: Contribution to journalArticle

Death Domain Receptors
TNF-Related Apoptosis-Inducing Ligand Receptors
Cell Death
Cells
Apoptosis
74 Citations (Scopus)

Retromer binding to FAM21 and the WASH complex is perturbed by the Parkinson disease-linked VPS35(D620N) mutation

McGough, I. J., Steinberg, F., Jia, D., Barbuti, P. A., McMillan, K. J., Heesom, K. J., Whone, A. L., Caldwell, M. A., Billadeau, D. D., Rosen, M. K. & Cullen, P. J., Jul 21 2014, In : Current Biology. 24, 14, p. 1670-1676 7 p.

Research output: Contribution to journalArticle

Wiskott-Aldrich Syndrome
Parkinson disease
endosomes
Endosomes
Parkinson Disease
61 Citations (Scopus)

The mitotic kinase aurora-A promotes distant metastases by inducing epithelial-to-mesenchymal transition in ER + breast cancer cells

D'Assoro, A., Liu, T., Quatraro, C., Amato, A., Opyrchal, M., Leontovich, A., Ikeda, Y. H., Ohmine, S., Lingle, W., Suman, V. J., Ecsedy, J., Iankov, I., Di Leonardo, A., Ayers-Inglers, J., Degnim, A. C., Billadeau, D. D., McCubrey, J., Ingle, J., Salisbury, J. L. & Galanis, E., Jan 30 2014, In : Oncogene. 33, 5, p. 599-610 12 p.

Research output: Contribution to journalArticle

Aurora Kinase A
Epithelial-Mesenchymal Transition
Breast Neoplasms
Neoplasm Metastasis
Phenotype