• 1275 Citations
  • 18 Scopus h-Index
20022020

Research output per year

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Research Output

2020

Acute Toxicities and Short-Term Patient Outcomes After Intensity-Modulated Proton Beam Radiation Therapy or Intensity-Modulated Photon Radiation Therapy for Esophageal Carcinoma: A Mayo Clinic Experience

Bhangoo, R. S., DeWees, T. A., Yu, N. Y., Ding, J. X., Liu, C., Golafshar, M. A., Rule, W. G., Vora, S. A., Ross, H. J., Ahn, D. H., Beamer, S. E., Jaroszewski, D. E., Hallemeier, C. L., Liu, W., Ashman, J. B. & Sio, T. T., 2020, (Accepted/In press) In : Advances in Radiation Oncology.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Homologous Recombination Repair Defect May Predict Treatment Response to Peptide Receptor Radionuclide Therapy for Neuroendocrine Tumors

Zhu, M., Bassam Sonbol, M., Halfdanarson, T. R., Hobday, T. J., Ahn, D., Ma, W. W. & Bekaii-Saab, T., 2020, (Accepted/In press) In : Oncologist.

Research output: Contribution to journalArticle

Open Access

Phase II Trial of Trifluridine/Tipiracil in Patients with Advanced, Refractory Biliary Tract Carcinoma

Chakrabarti, S., Zemla, T. J., Ahn, D. H., Ou, F. S., Fruth, B., Borad, M. J., Hartgers, M. L., Wessling, J., Walkes, R. L., Alberts, S. R., McWilliams, R. R., Liu, M. C., Durgin, L. M., Bekaii-Saab, T. S. & Mahipal, A., May 1 2020, In : Oncologist. 25, 5, p. 380-e763

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Real-World Dosing Patterns and Outcomes of Patients with Metastatic Pancreatic Cancer Treated with a Liposomal Irinotecan Regimen in the United States

Barzi, A., Miksad, R., Surinach, A., Corvino, F. A., Wang, S., Torres, A. Z., Mamlouk, K., Pulgar, S., Valderrama, A., Bekaii-Saab, T. & Ahn, D., Feb 1 2020, In : Pancreas. 49, 2, p. 193-200 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

The Role of Immune Checkpoint Inhibitors in Colorectal Adenocarcinoma

Almquist, D. R., Ahn, D. H. & Bekaii-Saab, T. S., Jun 1 2020, In : BioDrugs. 34, 3, p. 349-362 14 p.

Research output: Contribution to journalReview article

The Role of Maintenance Strategies in Metastatic Colorectal Cancer: A Systematic Review and Network Meta-analysis of Randomized Clinical Trials

Sonbol, M. B., Mountjoy, L. J., Firwana, B., Liu, A. J., Almader-Douglas, D., Mody, K., Hubbard, J., Borad, M., Ahn, D. H., Murad, M. H. & Bekaii-Saab, T., Mar 2020, In : JAMA Oncology. 6, 3

Research output: Contribution to journalArticle

5 Scopus citations

A Systematic Review and Network Meta-Analysis of Regorafenib and TAS-102 in Refractory Metastatic Colorectal Cancer

Sonbol, M. B., Benkhadra, R., Wang, Z., Firwana, B., Walden, D. J., Mody, K., Hubbard, J. M., Murad, M. H., Ahn, D. H. & Bekaii-Saab, T., Sep 1 2019, In : Oncologist. 24, 9, p. 1174-1179 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

CanStem111P trial: A Phase III study of napabucasin plus nab-paclitaxel with gemcitabine

Sonbol, M. B., Ahn, D. H., Goldstein, D., Okusaka, T., Tabernero, J., Macarulla, T., Reni, M., Li, C. P., O'Neil, B., Van Cutsem, E. & Bekaii-Saab, T., Apr 2019, In : Future Oncology. 15, 12, p. 1295-1302 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Circulating tumor DNA profiling of advanced biliary tract cancers

Mody, K., Kasi, P. M., Yang, J. D., Surapaneni, P. K., Bekaii-Saab, T., Ahn, D. H., Mahipal, A., Sonbol, M. B., Starr, J. S., Roberts, A., Nagy, R., Lanman, R. & Borad, M. J., Jan 1 2019, In : JCO Precision Oncology. 3

Research output: Contribution to journalArticle

8 Scopus citations

Gemcitabine, Cisplatin, and nab-Paclitaxel for the Treatment of Advanced Biliary Tract Cancers: A Phase 2 Clinical Trial

Shroff, R. T., Javle, M. M., Xiao, L., Kaseb, A. O., Varadhachary, G. R., Wolff, R. A., Raghav, K. P. S., Iwasaki, M., Masci, P., Ramanathan, R. K., Ahn, D. H., Bekaii-Saab, T. S. & Borad, M. J., Jun 2019, In : JAMA Oncology. 5, 6, p. 824-830 7 p.

Research output: Contribution to journalArticle

33 Scopus citations

Metastatic neuroendocrine tumor with cardiac involvement utilizing multi-modality imaging

Arsanjani, R., Agasthi, P., Ahn, D. H., Mookadam, F. & Yang, M., Jan 1 2019, In : Korean Circulation Journal. 49, 6, p. 557-558 2 p.

Research output: Contribution to journalComment/debate

Phase i immunotherapy trial with two chimeric HER-2 B-Cell peptide vaccines emulsified in montanide ISA 720VG and Nor-MDP adjuvant in patients with advanced solid tumors

Bekaii-Saab, T., Wesolowski, R., Ahn, D. H., Wu, C., Mortazavi, A., Lustberg, M., Ramaswamy, B., Fowler, J., Wei, L., Overholser, J. & Kaumaya, P. T. P., Jun 15 2019, In : Clinical Cancer Research. 25, 12, p. 3495-3507 13 p.

Research output: Contribution to journalArticle

5 Scopus citations

Regorafenib dose-optimisation in patients with refractory metastatic colorectal cancer (ReDOS): a randomised, multicentre, open-label, phase 2 study

Bekaii-Saab, T. S., Ou, F. S., Ahn, D. H., Boland, P. M., Ciombor, K. K., Heying, E. N., Dockter, T. J., Jacobs, N. L., Pasche, B. C., Cleary, J. M., Meyers, J. P., Desnoyers, R. J., McCune, J. S., Pedersen, K., Barzi, A., Chiorean, E. G., Sloan, J., Lacouture, M. E., Lenz, H. J. & Grothey, A. F., Aug 1 2019, In : The Lancet Oncology. 20, 8, p. 1070-1082 13 p.

Research output: Contribution to journalArticle

30 Scopus citations

Systemic treatment for metastatic or recurrent disease

Ahn, D. H. & Bekaii-Saab, T., Jan 1 2019, Esophageal Cancer: Prevention, Diagnosis and Therapy. Springer International Publishing, p. 275-287 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Therapeutic targeting strategies of cancer stem cells in gastrointestinal malignancies

Sonbol, M. B., Ahn, D. H. & Bekaii-Saab, T., Mar 1 2019, In : Biomedicines. 7, 1, 17.

Research output: Contribution to journalReview article

Open Access
6 Scopus citations

Watch and Wait in Rectal Cancer: Who's In and Who's Out?

Ahn, D. & Bekaii-Saab, T., Mar 1 2019, In : Journal of oncology practice. 15, 3, p. 133-134 2 p.

Research output: Contribution to journalArticle

2018

Biweekly cisplatin and gemcitabine in patients with advanced biliary tract cancer

Ahn, D., Reardon, J., Ahn, C. W., Bupathi, M., Mikhail, S., Wu, C. S. Y. & Bekaii-Saab, T., Apr 15 2018, In : International Journal of Cancer. 142, 8, p. 1671-1675 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

Cholangiocarcinoma with FGFR genetic aberrations: A unique clinical phenotype

Jain, A., Borad, M. J., Kelley, R. K., Wang, Y., Abdel-Wahab, R., Meric-Bernstam, F., Baggerly, K. A., Kaseb, A. O., Al-shamsi, H. O., Ahn, D. H., DeLeon, T., Bocobo, A. G., Bekaii-Saab, T., Shroff, R. T. & Javle, M., Jan 1 2018, In : JCO Precision Oncology. 2

Research output: Contribution to journalArticle

18 Scopus citations

Circulating interleukin-6 is associated with disease progression, but not cachexia in pancreatic cancer

Ramsey, M. L., Talbert, E., Ahn, D., Bekaii-Saab, T., Badi, N., Bloomston, P. M., Conwell, D. L., Cruz-Monserrate, Z., Dillhoff, M., Farren, M. R., Hinton, A., Krishna, S. G., Lesinski, G. B., Mace, T., Manilchuk, A., Noonan, A., Pawlik, T. M., Rajasekera, P. V., Schmidt, C., Guttridge, D. & 1 others, Hart, P. A., Jan 1 2018, (Accepted/In press) In : Pancreatology.

Research output: Contribution to journalArticle

2 Scopus citations

Efficacy of TAS-120, an irreversible fibroblast growth factor receptor (FGFR) inhibitor, in cholangiocarcinoma patients with FGFR pathway alterations who were previously treated with chemotherapy and other FGFR inhibitors

Meric-Bernstam, F., Arkenau, H., Tran, B., Bahleda, R., Kelley, R., Hierro, C., Ahn, D., Zhu, A., Javle, M., Winkler, R., He, H., Huang, J. & Goyal, L., Jun 1 2018, In : Annals of oncology : official journal of the European Society for Medical Oncology. 29, p. v100

Research output: Contribution to journalArticle

Open Access

Efficacy of TAS-120, an irreversible fibroblast growth factor receptor inhibitor (FGFRi), in patients with cholangiocarcinoma and FGFR pathway alterations previously treated with chemotherapy and other FGFRi's

Tran, B., Meric-Bernstam, F., Arkenau, H. T., Bahleda, R., Kelley, R. K., Hierro, C., Ahn, D., Zhu, A., Javle, M., Winkler, R., He, H., Huang, J. & Goyal, L., Nov 1 2018, In : Annals of oncology : official journal of the European Society for Medical Oncology. 29, p. ix49-ix50

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Novel immunotherapy strategies for hepatobiliary cancers

Deleon, T. T., Zhou, Y., Nagalo, B. M., Yokoda, R. T., Ahn, D. H., Ramanathan, R. K., Salomao, M. A., Aqel, B. A., Mahipal, A., Bekaii-Saab, T. S. & Borad, M. J., Sep 1 2018, In : Immunotherapy. 10, 12, p. 1077-1091 15 p.

Research output: Contribution to journalReview article

Novel targeted therapy strategies for biliary tract cancers and hepatocellular carcinoma

Deleon, T. T., Ahn, D., Bogenberger, J. M., Anastasiadis, P. Z., Arora, M., Ramanathan, R. K., Aqel, B. A., Vasmatzis, G., Truty, M., Oklu, R., Bekaii-Saab, T. & Borad, M. J., Mar 1 2018, In : Future Oncology. 14, 6, p. 553-566 14 p.

Research output: Contribution to journalReview article

11 Scopus citations

Phase 1b investigation of the MEK inhibitor binimetinib in patients with advanced or metastatic biliary tract cancer

Finn, R. S., Ahn, D., Javle, M. M., Tan, B. R., Weekes, C. D., Bendell, J. C., Patnaik, A., Khan, G. N., Laheru, D., Chavira, R., Christy-Bittel, J., Barrett, E., Sawyer, M. B. & Bekaii-Saab, T., May 22 2018, (Accepted/In press) In : Investigational New Drugs. p. 1-7 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Real-world dosing patterns of patients (pts) with metastatic pancreatic cancer (mPC) treated with liposomal irinotecan (nal-IRI) in US oncology clinics

Ahn, D., Barzi, A., Miksad, R. A., Surinach, A., Corvino, F. A., Valderrama, A., Mamlouk, K., Pulgar, S. & Bekaii-Saab, T., Oct 1 2018, In : Annals of oncology : official journal of the European Society for Medical Oncology. 29, p. viii251

Research output: Contribution to journalArticle

Open Access

Regorafenib Dose Optimization Study (ReDOS): Randomized phase II trial to evaluate escalating dosing strategy and pre-emptive topical steroids for regorafenib in refractory metastatic colorectal cancer (mCRC) - An ACCRU Network study

Bekaii-Saab, T., Ou, F., Anderson, D., Ahn, D., Boland, P., Ciombor, K., Jacobs, N., Desnoyers, R., Cleary, J., Meyers, J., Chiorean, E., Pedersen, K., Barzi, A., Sloan, J., McCune, J., Lacouture, M., Lenz, H. & Grothey, A., Jun 1 2018, In : Annals of oncology : official journal of the European Society for Medical Oncology. 29, p. v105

Research output: Contribution to journalArticle

Open Access

Small Intestine Neuroendocrine Tumor in a Patient With MUTYH Adenomatous Polyposis—Case Report and SEER Analysis

Weidner, T. K., Kidwell, J. T., Glasgow, A. E., Menias, C. O., Ahn, D., Pai, R., Heigh, R. I. & Mishra, N., Jan 1 2018, (Accepted/In press) In : Clinical Colorectal Cancer.

Research output: Contribution to journalArticle

2017

A modified regimen of biweekly gemcitabine and nab-paclitaxel in patients with metastatic pancreatic cancer is both tolerable and effective: A retrospective analysis

Ahn, D., Krishna, K., Blazer, M., Reardon, J., Wei, L., Wu, C., Ciombor, K. K., Noonan, A. M., Mikhail, S. & Bekaii-Saab, T., Feb 1 2017, In : Therapeutic Advances in Medical Oncology. 9, 2, p. 75-82 8 p.

Research output: Contribution to journalArticle

24 Scopus citations
14 Scopus citations

Continued disappointments with targeted agents in first-line therapy of advanced gastric cancers

Ahn, D. & Grothey, A. F., 2017, (Accepted/In press) In : The Lancet Oncology.

Research output: Contribution to journalArticle

2 Scopus citations

Overall survival and clinical characteristics of BRCA-associated cholangiocarcinoma: Amulticenter retrospective study

Golan, T., Raitses-Gurevich, M., Kelley, R. K., Bocobo, A. G., Borgida, A., Shroff, R. T., Holter, S., Gallinger, S., Ahn, D., Aderka, D., Apurva, J., Bekaii-Saab, T., Friedman, E. & Javle, M., Jul 1 2017, In : Oncologist. 22, 7, p. 804-810 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

Response to Drs von Hoff and Renschler

Ahn, D. & Bekaii-Saab, T., Jun 1 2017, In : Therapeutic Advances in Medical Oncology. 9, 6, p. 445-446 2 p.

Research output: Contribution to journalLetter

Second-line treatment in patients with pancreatic ductal adenocarcinoma: A meta-analysis

Sonbol, M. B., Firwana, B., Wang, Z., Almader-Douglas, D., Borad, M. J., Makhoul, I., Ramanathan, R. K., Ahn, D. & Bekaii-Saab, T., Dec 1 2017, In : Cancer. 123, 23, p. 4680-4686 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Signaling pathways as therapeutic targets in biliary tract cancer

Yang, J., Farren, M. R., Ahn, D., Bekaii-Saab, T. & Lesinski, G. B., May 4 2017, In : Expert Opinion on Therapeutic Targets. 21, 5, p. 485-498 14 p.

Research output: Contribution to journalReview article

1 Scopus citations

Targeting the stroma in pancreatic cancer

Ahn, D. & Ramanathan, R. K., Dec 1 2017, In : Chinese Clinical Oncology. 6, 6, 65.

Research output: Contribution to journalReview article

2 Scopus citations
3 Scopus citations

The Efficacy of Adjuvant Chemotherapy in Patients with Stage II/III Resected Rectal Cancer Treated with Neoadjuvant Chemoradiation Therapy

Ahn, D., Wu, C., Wei, L., Williams, T. M., Wuthrick, E., Abdel-Misih, S., Harzman, A., Husain, S., Schmidt, C., Goldberg, R. M. & Bekaii-Saab, T., Jan 1 2017, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 40, 6, p. 531-534 4 p.

Research output: Contribution to journalArticle

4 Scopus citations

Virotherapies in pancreatic cancer

Ahn, D. & Ramanathan, R. K., Sep 27 2017, Current and Emerging Therapies in Pancreatic Cancer. Springer International Publishing, p. 309-322 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2016

Adjuvant Chemotherapy for Rectal Cancer After Neoadjuvant Treatment: FOLFOX, 5-FU, or Observation

Ahn, D. & Bekaii-Saab, T., Oct 1 2016, In : Current Colorectal Cancer Reports. 12, 5, p. 260-265 6 p.

Research output: Contribution to journalReview article

Adjuvant therapy for pancreas cancer in an era of value based cancer care

Ahn, D. H., Williams, T. M., Goldstein, D. A., El-Rayes, B. & Bekaii-Saab, T., Jan 1 2016, In : Cancer Treatment Reviews. 42, p. 10-17 8 p.

Research output: Contribution to journalReview article

12 Scopus citations

Biliary cancer: Utility of next-generation sequencing for clinical management

Javle, M., Bekaii-Saab, T., Jain, A., Wang, Y., Kelley, R. K., Wang, K., Kang, H. C., Catenacci, D., Ali, S., Krishnan, S., Ahn, D., Bocobo, A. G., Zuo, M., Kaseb, A., Miller, V., Stephens, P. J., Meric-Bernstam, F., Shroff, R. & Ross, J., Dec 15 2016, In : Cancer. 122, 24, p. 3838-3847 10 p.

Research output: Contribution to journalArticle

80 Scopus citations

Colorectal clinical trials: What is on the horizon?

Ahn, D. & Goldberg, R. M., Feb 1 2016, In : Future Oncology. 12, 4, p. 525-531 7 p.

Research output: Contribution to journalReview article

1 Scopus citations

Genomic diversity of colorectal cancer: Changing landscape and emerging targets

Ahn, D., Ciombor, K. K., Mikhail, S. & Bekaii-Saab, T., Jul 7 2016, In : World Journal of Gastroenterology. 22, 25, p. 5668-5677 10 p.

Research output: Contribution to journalReview article

7 Scopus citations

Modified irinotecan and infusional 5-fluorouracil (mFOLFIRI) in patients with refractory advanced pancreas cancer (APC): a single-institution experience

Bupathi, M., Ahn, D. H., Wu, C., Ciombor, K. K., Stephens, J. A., Reardon, J., Goldstein, D. A. & Bekaii-Saab, T., Apr 1 2016, In : Medical Oncology. 33, 4, 37.

Research output: Contribution to journalArticle

1 Scopus citations

Next-generation sequencing survey of biliary tract cancer reveals the association between tumor somatic variants and chemotherapy resistance

Ahn, D., Javle, M., Ahn, C. W., Jain, A., Mikhail, S., Noonan, A. M., Wu, C., Shroff, R. T., Chen, J. L. & Bekaii-Saab, T., Dec 1 2016, In : Cancer. 122, 23, p. 3657-3666 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Randomized Phase 2 Trial of the Oncolytic Virus Pelareorep (Reolysin) in Upfront Treatment of Metastatic Pancreatic Adenocarcinoma

Noonan, A. M., Farren, M. R., Geyer, S. M., Huang, Y., Tahiri, S., Ahn, D., Mikhail, S., Ciombor, K. K., Pant, S., Aparo, S., Sexton, J., Marshall, J. L., Mace, T. A., Wu, C. S., El-Rayes, B., Timmers, C. D., Zwiebel, J., Lesinski, G. B., Villalona-Calero, M. A. & Bekaii-Saab, T., Jun 1 2016, In : Molecular Therapy. 24, 6, p. 1150-1158 9 p.

Research output: Contribution to journalArticle

44 Scopus citations