• 17792 Citations
  • 71 Scopus h-Index
1989 …2019
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Research Output 1989 2019

2019

Ability of dual-energy CT to detect silicone gel breast implant rupture and nodal silicone spread

Glazebrook, K. N., Doerge, S., Leng, S., Drees, T. A., Hunt, K. N., Zingula, S. N., Pruthi, S., Geske, J. R., Carter, R. E., McCollough, C. H. & Fletcher, J. G., Apr 1 2019, In : American Journal of Roentgenology. 212, 4, p. 933-942 10 p.

Research output: Contribution to journalArticle

Silicone Gels
Breast Implants
Silicones
Rupture
Breast

A deep learning- and partial least square regression-based model observer for a low-contrast lesion detection task in CT

Gong, H., Yu, L., Leng, S., Dilger, S. K., Ren, L., Zhou, W., Fletcher, J. G. & McCollough, C. H., Jan 1 2019, In : Medical physics.

Research output: Contribution to journalArticle

Least-Squares Analysis
Learning
Noise
Liver
Radiation

Clinical assessment of metal artifact reduction methods in dual-energy CT examinations of instrumented spines

Long, Z., DeLone, D. R., Kotsenas, A. L., Lehman, V. T., Nagelschneider, A. A., Michalak, G. J., Fletcher, J. G., McCollough, C. H. & Yu, L., Feb 1 2019, In : American Journal of Roentgenology. 212, 2, p. 395-401 7 p.

Research output: Contribution to journalArticle

Artifacts
Spine
Metals
Bone and Bones

Clinical utility of virtual noncalcium dual-energy CT in imaging of the pelvis and hip

Baffour, F. I., Glazebrook, K. N., Morris, J. M., Michalak, G. J., Fletcher, J. G., Leng, S. & McCollough, C. H., Jan 1 2019, In : Skeletal Radiology.

Research output: Contribution to journalReview article

Pelvis
Hip
Bone Marrow
Pathology
Edema

Computed Tomography Cholangiography Using the Magnetic Resonance Contrast Agent Gadoxetate Disodium: A Phantom Study

Dilger, S. K. N., Nelson, N., Venkatesh, S. K., Ehman, E., Fidler, J. L., Fletcher, J. G., McCollough, C. H. & Yu, L., Sep 1 2019, In : Investigative radiology. 54, 9, p. 572-579 8 p.

Research output: Contribution to journalArticle

Cholangiography
Gadolinium
Contrast Media
Noise
Magnetic Resonance Spectroscopy
2 Citations (Scopus)

Computed Tomography Technology - And Dose - In the 21st Century

McCollough, C. H., Feb 1 2019, In : Health Physics. 116, 2, p. 157-162 6 p.

Research output: Contribution to journalArticle

Tomography
Technology
Photons
X-Rays
Noise

Correlation between a deep-learning-based model observer and human observer for a realistic lung nodule localization task in chest CT

Gong, H., Walther, A., Hu, Q., Koo, C. W., Takahashi, E. A., Levin, D. L., Johnson, T. F., Hora, M. J., Leng, S., Fletcher, J. G., McCollough, C. H. & Yu, L., Jan 1 2019, Medical Imaging 2019: Image Perception, Observer Performance, and Technology Assessment. Nishikawa, R. M. & Samuelson, F. W. (eds.). SPIE, 109520K. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10952).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

chest
nodules
lungs
learning
Thorax
1 Citation (Scopus)
Cryosurgery
Ice
Pelvis
Spine
Tomography
1 Citation (Scopus)

Dual-source photon counting detector CT with a tin filter: a phantom study on iodine quantification performance

Tao, A., Huang, R., Tao, S., Michalak, G. J., McCollough, C. H. & Leng, S., May 31 2019, In : Physics in medicine and biology. 64, 11, 1 p.

Research output: Contribution to journalArticle

Tin
Photons
Iodine
Research Design
Least-Squares Analysis
Photons
Gadolinium
Bismuth
Noise
Head
1 Citation (Scopus)

Findings of CT-Derived Bone Strength Assessment in Inflammatory Bowel Disease Patients Undergoing CT Enterography in Clinical Practice

Maldonado, F. J., Al Bawardy, B. F., Nehra, A. K., Lee, Y. S., Bruining, D. H., Adkins, M. C., Keaveny, T. M., Johnson, M. P., Fidler, J. L., McCollough, C. H. & Fletcher, J. G., May 4 2019, In : Inflammatory bowel diseases. 25, 6, p. 1072-1079 8 p.

Research output: Contribution to journalArticle

Inflammatory Bowel Diseases
Bone and Bones
Metabolic Bone Diseases
Guidelines
Bone Density

Forward model for propagation-based X-ray phase contrast imaging in parallel- and conebeam geometry

Shanblatt, E. R., Sung, Y., Gupta, R., Nelson, B. J., Leng, S., Graves, W. S. & McCollough, C. H., Jan 1 2019, In : Optics Express. 27, 4, p. 4504-4521 18 p.

Research output: Contribution to journalArticle

phase contrast
propagation
geometry
x rays
cones
1 Citation (Scopus)

High-Resolution Chest Computed Tomography Imaging of the Lungs: Impact of 1024 Matrix Reconstruction and Photon-Counting Detector Computed Tomography

Bartlett, D. J., Koo, C. W., Bartholmai, B. J., Rajendran, K., Weaver, J. M., Halaweish, A. F., Leng, S., McCollough, C. H. & Fletcher, J. G., Mar 1 2019, In : Investigative Radiology. 54, 3, p. 129-137 9 p.

Research output: Contribution to journalArticle

Photons
Bronchi
Thorax
Tomography
Lung

Impact of prior information on material decomposition in dual- and multienergy computed tomography

Ren, L., Tao, S., Rajendran, K., McCollough, C. H. & Yu, L., Jan 1 2019, In : Journal of Medical Imaging. 6, 1, 013503.

Research output: Contribution to journalArticle

Tomography
Iodine
Noise
Water
Gadolinium
Iodine
Noise
Photons
X-Rays
Whole-Body Counting

Individualized Delay for Abdominal Computed Tomography Angiography Bolus-Tracking Based on Sequential Monitoring: Increased Aortic Contrast Permits Decreased Injection Rate and Lower Iodine Dose

Gutjahr, R., Fletcher, J. G., Lee, Y. S., Halaweish, A. F., Suresh, V., Weber, N. M., Vrtiska, T. J., Williamson, E. E., Schmidt, B. & McCollough, C. H., Jul 1 2019, In : Journal of computer assisted tomography. 43, 4, p. 612-618 7 p.

Research output: Contribution to journalArticle

Licensure
Iodine
Injections
Tomography
Software
1 Citation (Scopus)

Lead shielding in pediatric chest CT: Effect of apron placement outside the scan volume on radiation dose reduction

Yu, L., Bruesewitz, M. R., Vrieze, T. J. & McCollough, C. H., Jan 1 2019, In : American Journal of Roentgenology. 212, 1, p. 151-156 6 p.

Research output: Contribution to journalArticle

Thorax
Radiation
Pediatrics
Pelvis
Abdomen
Theoretical Models
Liver
Water
Task Performance and Analysis
ROC Curve
1 Citation (Scopus)
Liver
Water
Noise
Computer-Assisted Image Processing
ROC Curve

Material decomposition in photon-counting-detector CT: Threshold or bin images?

Ren, L., Tao, S., McCollough, C. H. & Yu, L., Jan 1 2019, Medical Imaging 2019: Physics of Medical Imaging. Bosmans, H., Chen, G-H. & Schmidt, T. G. (eds.). SPIE, 109482S. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10948).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Bins
Least-Squares Analysis
Photons
counting
Detectors

Multi-contrast imaging on dual-source photon-counting-detector (PCD) CT

Tao, S., Rajendran, K., McCollough, C. H. & Leng, S., Jan 1 2019, Medical Imaging 2019: Physics of Medical Imaging. Bosmans, H., Chen, G-H. & Schmidt, T. G. (eds.). SPIE, 109484L. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10948).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Photons
Light sources
counting
Detectors
Imaging techniques

Multi-energy CT with triple x-ray beams and photon-counting-detector CT for simultaneous imaging of two contrast agents: An experimental comparison

Ren, L., McCollough, C. H. & Yu, L., Jan 1 2019, Medical Imaging 2019: Physics of Medical Imaging. Bosmans, H., Chen, G-H. & Schmidt, T. G. (eds.). SPIE, 109481B. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10948).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Photons
Iodine
Contrast Media
counting
Bismuth

Optimal acquisition setting for dual-contrast imaging with gadolinium and iodine on a research whole-body photon-counting-detector (PCD) CT

Tao, S., Wu, Y., Rajendran, K., McCollough, C. H. & Leng, S., Jan 1 2019, Medical Imaging 2019: Physics of Medical Imaging. Bosmans, H., Chen, G-H. & Schmidt, T. G. (eds.). SPIE, 109484I. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10948).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Whole-Body Counting
Gadolinium
gadolinium
Iodine
Photons
1 Citation (Scopus)

Photon-counting detector CT: System design and clinical applications of an emerging technology

Leng, S., Bruesewitz, M., Tao, S., Rajendran, K., Halaweish, A. F., Campeau, N. G., Fletcher, J. G. & McCollough, C. H., May 1 2019, In : Radiographics. 39, 3, p. 729-743 15 p.

Research output: Contribution to journalArticle

Photons
Technology
Contrast Media
Artifacts
Noise

Quantitative cartilage imaging using spectral photon-counting detector based computed tomography

Rajendran, K., Tao, S., Benike, A., Leng, S. & McCollough, C. H., Jan 1 2019, Medical Imaging 2019: Biomedical Applications in Molecular, Structural, and Functional Imaging. Gimi, B. & Krol, A. (eds.). SPIE, 109531A. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10953).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

cartilage
Cartilage
Glycosaminoglycans
Photons
Tomography

Reducing radiation dose for multi-phase contrast-enhanced dual energy renal CT: pilot study evaluating prior iterative reconstruction

Navin, P. J., Kim, B., Wells, M., Khandelwal, A., Halaweish, A. F., Moen, T. R., Johnson, M. P., McCollough, S., Lee, Y. S., Leng, S., McCollough, C. H. & Fletcher, J. G., Jan 1 2019, (Accepted/In press) In : Abdominal Radiology.

Research output: Contribution to journalArticle

Radiation Dosage
Kidney Neoplasms
Radiation
Kidney
Computer-Assisted Image Processing
3 Citations (Scopus)

Reduction of Metal Artifacts and Improvement in Dose Efficiency Using Photon-Counting Detector Computed Tomography and Tin Filtration

Zhou, W., Bartlett, D. J., Diehn, F. E., Glazebrook, K. N., Kotsenas, A. L., Carter, R. E., Fletcher, J. G., McCollough, C. H. & Leng, S., Apr 1 2019, In : Investigative radiology. 54, 4, p. 204-211 8 p.

Research output: Contribution to journalArticle

Tin
Photons
Artifacts
Metals
Tomography

Renal Adiposity Does not Preclude Quantitative Assessment of Renal Function Using Dual-Energy Multidetector CT in Mildly Obese Human Subjects

Ferguson, C. M., Eirin, A., Michalak, G. J., Hedayat, F., Abumoawad, A. M., Hedayat, A. F., Zhu, X., Textor, S. C., McCollough, C. H. & Lerman, L. O., Jan 1 2019, (Accepted/In press) In : Academic Radiology.

Research output: Contribution to journalArticle

Adiposity
Kidney
Multidetector Computed Tomography
Iodine
Aorta

Simulation of CT images reconstructed with different kernels using a convolutional neural network and its implications for efficient CT workflow

Missert, A. D., Leng, S., McCollough, C. H., Fletcher, J. G. & Yu, L., Jan 1 2019, Medical Imaging 2019: Physics of Medical Imaging. Bosmans, H., Chen, G-H. & Schmidt, T. G. (eds.). SPIE, 109482Y. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10948).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Workflow
Tomography
tomography
X-Ray Computed Tomography Scanners
Neural networks

Symptomatic and Radiographic Manifestations of Kidney Stone Recurrence and Their Prediction by Risk Factors: A Prospective Cohort Study

D'Costa, M. R., Haley, W. E., Mara, K. C., Enders, F. T., Vrtiska, T. J., Pais, V. M., Jacobsen, S. J., McCollough, C. H., Lieske, J. C. & Rule, A. D., Jul 1 2019, In : Journal of the American Society of Nephrology : JASN. 30, 7, p. 1251-1260 10 p.

Research output: Contribution to journalArticle

Kidney Calculi
Cohort Studies
Prospective Studies
Recurrence
Self Report

Understanding, justifying, and optimizing radiation exposure for CT imaging in nephrourology

Ferrero, A., Takahashi, N., Vrtiska, T. J., Krambeck, A. E., Lieske, J. C. & McCollough, C. H., Jan 1 2019, In : Nature Reviews Urology.

Research output: Contribution to journalReview article

Radiation
Diagnostic Imaging
Ionizing Radiation
Neoplasms
Urinary Calculi

Visibility guided phase contrast denoising

Nelson, B., Koenig, T., Shanblatt, E., Leng, S. & McCollough, C. H., Jan 1 2019, Medical Imaging 2019: Physics of Medical Imaging. Bosmans, H., Chen, G-H. & Schmidt, T. G. (eds.). SPIE, 109484V. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10948).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Interferometry
phase contrast
visibility
Visibility
low visibility
2018
9 Citations (Scopus)

150-μm Spatial Resolution Using Photon-Counting Detector Computed Tomography Technology: Technical Performance and First Patient Images

Leng, S., Rajendran, K., Gong, H., Zhou, W., Halaweish, A. F., Henning, A., Kappler, S., Baer, M., Fletcher, J. G. & McCollough, C. H., Nov 1 2018, In : Investigative Radiology. 53, 11, p. 655-662 8 p.

Research output: Contribution to journalArticle

Photons
Tomography
Technology
Noise
Research Ethics Committees
1 Citation (Scopus)

Breathe New Life Into Your Chest CT Exams: Using Advanced Acquisition and Postprocessing Techniques

Weber, N. M., Koo, C. W., Yu, L., Bartholmai, B. J., Halaweish, A. F., McCollough, C. H. & Fletcher, J. G., Jan 1 2018, (Accepted/In press) In : Current Problems in Diagnostic Radiology.

Research output: Contribution to journalArticle

Thorax
Tomography
Artifacts
Lung Diseases
X-Rays
2 Citations (Scopus)

Characterization of Urinary Stone Composition by Use of Whole-body, Photon-counting Detector CT

Ferrero, A., Gutjahr, R., Halaweish, A. F., Leng, S. & McCollough, C. H., Jan 1 2018, (Accepted/In press) In : Academic Radiology.

Research output: Contribution to journalArticle

Whole-Body Counting
Urinary Calculi
Photons
Tomography
ROC Curve
1 Citation (Scopus)

Comparison of a photon-counting-detector CT with an energy-integrating-detector CT for temporal bone imaging: A cadaveric study

Zhou, W., Lane, J. I., Carlson, M. L., Bruesewitz, M. R., Witte, R. J., Koeller, K. K., Eckel, L. J., Carter, R. E., McCollough, C. H. & Leng, S., Sep 1 2018, In : American Journal of Neuroradiology. 39, 9, p. 1733-1738 6 p.

Research output: Contribution to journalArticle

Temporal Bone
Photons
Stapes
Comb and Wattles
Anatomy

Concern about a recently published paper in the European Journal of Radiology

McCollough, C. H., Leng, S., Yu, L. & Ferrero, A., Dec 1 2018, In : European Journal of Radiology. 109, 1 p.

Research output: Contribution to journalLetter

Radiology
1 Citation (Scopus)

Correlation between model observers in uniform background and human observers in patient liver background for a low-contrast detection task in CT

Gong, H., Yu, L., Leng, S., DIlger, S., Zhou, W., Ren, L. & McCollough, C. H., Jan 1 2018, Medical Imaging 2018: Image Perception, Observer Performance, and Technology Assessment. SPIE, Vol. 10577. 105770M

Research output: Chapter in Book/Report/Conference proceedingConference contribution

liver
Liver
lesions
Computerized tomography
Image quality
4 Citations (Scopus)

Detection and characterization of renal stones by using photon-counting-based CT

Marcus, R. P., Fletcher, J. G., Ferrero, A., Leng, S., Halaweish, A. F., Gutjahr, R., Vrtiska, T. J., Wells, M., Enders, F. T. & McCollough, C. H., Nov 1 2018, In : Radiology. 289, 2, p. 436-442 7 p.

Research output: Contribution to journalArticle

Photons
Kidney
Cone-Beam Computed Tomography
Uric Acid
Research

Determination of optimal image type and lowest detectable concentration for iodine detection on a photon counting detector-based multi-energy CT system

Zhou, W., Schornak, R., Michalak, G., Weaver, J., Abdurakhimova, D., Ferrero, A., Fetterly, K. A., McCollough, C. H. & Leng, S., Jan 1 2018, Medical Imaging 2018: Physics of Medical Imaging. SPIE, Vol. 10573. 105734U

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Iodine
Photons
iodine
low concentrations
counting
6 Citations (Scopus)

Dual-source multienergy CT with triple or quadruple x-ray beams

Yu, L., Ren, L., Li, Z., Leng, S. & McCollough, C. H., Jul 1 2018, In : Journal of Medical Imaging. 5, 3, 033502.

Research output: Contribution to journalArticle

Photons
X-Rays
Contrast Media
Computer Simulation
Noise

Estimating a size-specific dose for helical head CT examinations using Monte Carlo simulation methods

Hardy, A. J., Bostani, M., Hernandez, A. M., Zankl, M., McCollough, C. H., Cagnon, C., Boone, J. M. & McNitt-Gray, M., Jan 1 2018, (Accepted/In press) In : Medical Physics.

Research output: Contribution to journalArticle

Monte Carlo Method
Spiral Computed Tomography
Head
Bone and Bones
Brain

Estimating lung, breast, and effective dose from low-dose lung cancer screening CT exams with tube current modulation across a range of patient sizes

Hardy, A. J., Bostani, M., McMillan, K., Zankl, M., McCollough, C. H., Cagnon, C. & McNitt-Gray, M., Jan 1 2018, (Accepted/In press) In : Medical Physics.

Research output: Contribution to journalArticle

Early Detection of Cancer
Lung Neoplasms
Breast
Lung
Thorax

Evaluation of a photon counting Medipix3RX cadmium zinc telluride spectral x-ray detector

Marsh, J. F., Jorgensen, S. M., Rundle, D. S., Vercnocke, A. J., Leng, S., Butler, P. H., McCollough, C. H. & Ritman, E. L., Oct 1 2018, In : Journal of Medical Imaging. 5, 4, 043503.

Research output: Contribution to journalArticle

X-Ray Microtomography
Photons
X-Rays
Brachytherapy
Linear Models
1 Citation (Scopus)

Evaluation of projection- and dual-energy-based methods for metal artifact reduction in CT using a phantom study

Long, Z., Bruesewitz, M. R., Delone, D. R., Morris, J. M., Amrami, K. K., Adkins, M. C., Glazebrook, K. N., Kofler, J. M., Leng, S., McCollough, C. H., Fletcher, J. G., Halaweish, A. F. & Yu, L., Jan 1 2018, (Accepted/In press) In : Journal of Applied Clinical Medical Physics.

Research output: Contribution to journalArticle

Artifacts
artifacts
projection
Metals
evaluation
1 Citation (Scopus)

Imaging findings of mammary and systemic silicone deposition secondary to breast implants

Samreen, N., Glazebrook, K. N., Bhatt, A., Venkatesh, S. K., Mcmenomy, B. P., Chandra, A., Leng, S., Adler, K. E. & McCollough, C. H., Jan 1 2018, In : British Journal of Radiology. 91, 1089, 20180098.

Research output: Contribution to journalReview article

Breast Implants
Silicones
Breast
Rupture
Spleen

Impact of Effective Detector Pixel and CT Voxel Size on Accurate Estimation of Blood Volume in Opacified Microvasculature

Sheikhzadeh, M., Vercnocke, A. J., Tao, S., Rajendran, K., Leng, S., Ritman, E. L. & McCollough, C. H., Jan 1 2018, (Accepted/In press) In : Academic Radiology.

Research output: Contribution to journalArticle

Microvessels
Blood Volume
Photons
Swine
X-Ray Microtomography

Impact of photon counting detector technology on kV selection and diagnostic workflow in CT

Zhou, W., Abdurakhimova, D., Bruesewitz, M., Halaweish, A., McCollough, C. H. & Leng, S., Jan 1 2018, Medical Imaging 2018: Physics of Medical Imaging. SPIE, Vol. 10573. 105731C

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Workflow
Iodine
Photons
Noise
counting
3 Citations (Scopus)

Intrarenal fat deposition does not interfere with the measurement of single-kidney perfusion in obese swine using multi-detector computed tomography

Ferguson, C. M., Eirin, A., Michalak, G. J., Hedayat, A. F., Abumoawad, A., Saad, A., Zhu, X., Textor, S. C., McCollough, C. H. & Lerman, L. O., Jan 1 2018, (Accepted/In press) In : Journal of Cardiovascular Computed Tomography.

Research output: Contribution to journalArticle

Swine
Perfusion
Fats
Tomography
Kidney