Claudia F Lucchinetti, MD

  • 35035 Citations
  • 84 Scopus h-Index
1988 …2020

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2007

Myelin transcription factor 1 (Myt1) expression in demyelinated lesions of rodent and human CNS

Vana, A. C., Lucchinetti, C. F., Le, T. Q. & Armstrong, R. C., May 2007, In : Glia. 55, 7, p. 687-697 11 p.

Research output: Contribution to journalArticle

34 Scopus citations

Ornithine transcarbamylase deficiency presenting as encephalopathy during adulthood following bariatric surgery

Hu, W. T., Kantarci, O. H., Merritt, J. L., McGrann, P., Dyck, P. J. B., Lucchinetti, C. F. & Tippmann-Peikert, M., Jan 1 2007, In : Archives of neurology. 64, 1, p. 126-128 3 p.

Research output: Contribution to journalArticle

34 Scopus citations

Pathogenic potential of IgG binding to water channel extracellular domain in neuromyelitis optica

Hinson, S. R., Pittock, S. J., Lucchinetti, C. F., Roemer, S. F., Fryer, J. P., Kryzer, T. J. & Lennon, V. A., Dec 2007, In : Neurology. 69, 24, p. 2221-2231 11 p.

Research output: Contribution to journalArticle

348 Scopus citations

Pattern-specific loss of aquaporin-4 immunoreactivity distinguishes neuromyelitis optica from multiple sclerosis

Roemer, S. F., Parisi, J. E., Lennon, V. A., Benarroch, E. E., Lassmann, H., Bruck, W., Mandler, R. N., Weinshenker, B. G., Pittock, S. J., Wingerchuk, D. M. & Lucchinetti, C. F., May 2007, In : Brain. 130, 5, p. 1194-1205 12 p.

Research output: Contribution to journalArticle

526 Scopus citations

The immunopathology of multiple sclerosis: An overview

Lassmann, H., Brück, W. & Lucchinetti, C. F., Apr 1 2007, In : Brain Pathology. 17, 2, p. 210-218 9 p.

Research output: Contribution to journalArticle

727 Scopus citations

Widespread demyelination in the cerebellar cortex in multiple sclerosis

Kutzelnigg, A., Faber-Rod, J. C., Bauer, J., Lucchinetti, C. F., Sorensen, P. S., Laursen, H., Stadelmann, C., Brück, W., Rauschka, H., Schmidbauer, M. & Lassmann, H., Jan 1 2007, In : Brain Pathology. 17, 1, p. 38-44 7 p.

Research output: Contribution to journalArticle

220 Scopus citations
2006

Brain abnormalities in neuromyelitis optica

Pittock, S. J., Lennon, V. A., Krecke, K., Wingerchuk, D. M., Lucchinetti, C. F. & Weinshenker, B. G., Mar 1 2006, In : Archives of neurology. 63, 3, p. 390-396 7 p.

Research output: Contribution to journalArticle

552 Scopus citations

Chemokine receptors as biomarkers in multiple sclerosis

Fox, R. J., Kivisäkk, P., Lee, J. C., Tucky, B., Lucchinetti, C., Rudick, R. A. & Ransohoff, R. M., 2006, In : Disease Markers. 22, 4, p. 227-233 7 p.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations
24 Scopus citations
506 Scopus citations
446 Scopus citations
Open Access
61 Scopus citations

Pattern of T2 hypointensity associated with ring-enhancing brain lesions can help to differentiate pathology

Schwartz, K. M., Erickson, B. J. & Lucchinetti, C., Mar 1 2006, In : Neuroradiology. 48, 3, p. 143-149 7 p.

Research output: Contribution to journalArticle

74 Scopus citations

Remyelination is extensive in a subset of multiple sclerosis patients

Patrikios, P., Stadelmann, C., Kutzelnigg, A., Rauschka, H., Schmidbauer, M., Laursen, H., Sorensen, P. S., Brück, W., Lucchinetti, C. & Lassmann, H., Dec 2006, In : Brain. 129, 12, p. 3165-3172 8 p.

Research output: Contribution to journalArticle

467 Scopus citations

Revised diagnostic criteria for neuromyelitis optica

Wingerchuk, D. M., Lennon, V. A., Pittock, S. J., Lucchinetti, C. F. & Weinshenker, B. G., May 1 2006, In : Neurology. 66, 10, p. 1485-1489 5 p.

Research output: Contribution to journalArticle

2128 Scopus citations

Steroid-responsive encephalopathy associated with autoimmune thyroiditis

Castillo, P., Woodruff, B., Caselli, R., Vernino, S., Lucchinetti, C., Swanson, J., Noseworthy, J., Aksamit, A., Carter, J., Sirven, J., Hunder, G., Fatourechi, V., Mokri, B., Drubach, D., Pittock, S., Lennon, V. & Boeve, B., Feb 1 2006, In : Archives of neurology. 63, 2, p. 197-202 6 p.

Research output: Contribution to journalArticle

336 Scopus citations
2005

Amphiphysin autoimmunity: Paraneoplastic accompaniments

Pittock, S. J., Lucchinetti, C. F., Parisi, J. E., Benarroch, E. E., Mokri, B., Stephan, C. L., Kim, K. K., Kilimann, M. W. & Lennon, V. A., Jul 1 2005, In : Annals of neurology. 58, 1, p. 96-107 12 p.

Research output: Contribution to journalArticle

222 Scopus citations

A randomized controlled crossover trial of aspirin for fatigue in multiple sclerosis

Wingerchuk, D. M., Benarroch, E. E., O'Brien, P. C., Keegan, B. M., Lucchinetti, C. F., Noseworthy, J. H., Weinshenker, B. G. & Rodriguez, M., Apr 12 2005, In : Neurology. 64, 7, p. 1267-1269 3 p.

Research output: Contribution to journalArticle

85 Scopus citations

CCR5Δ32 polymorphism effects on CCR5 expression, patterns of immunopathology and disease course in multiple sclerosis

Kantarci, O. H., Morales, Y., Ziemer, P. A., Hebrink, D. D., Mahad, D. J., Atkinson, E. J., Achenbach, S. J., De Andrade, M., Mack, M., Ransohoff, R. M., Lassmann, H., Bruck, W., Weinshenker, B. G. & Lucchinetti, C. F., Dec 1 2005, In : Journal of neuroimmunology. 169, 1-2, p. 137-143 7 p.

Research output: Contribution to journalArticle

30 Scopus citations

Clinical course, pathological correlations, and outcome of biopsy proved inflammatory demyelinating disease

Pittock, S. J., McClelland, R. L., Achenbach, S. J., Konig, F., Bitsch, A., Brück, W., Lassmann, H., Parisi, J. E., Scheithauer, B. W., Rodriguez, M., Weinshenker, B. G. & Lucchinetti, C. F., Dec 2005, In : Journal of Neurology, Neurosurgery and Psychiatry. 76, 12, p. 1693-1697 5 p.

Research output: Contribution to journalArticle

47 Scopus citations

Cortical demyelination and diffuse white matter injury in multiple sclerosis

Kutzelnigg, A., Lucchinetti, C. F., Stadelmann, C., Brück, W., Rauschka, H., Bergmann, M., Schmidbauer, M., Parisi, J. E. & Lassmann, H., Nov 2005, In : Brain. 128, 11, p. 2705-2712 8 p.

Research output: Contribution to journalArticle

1138 Scopus citations

Relation between humoral pathological changes in multiple sclerosis and response to therapeutic plasma exchange

Keegan, M., König, F., McClelland, R., Brück, W., Morales, Y., Bitsch, A., Panitch, H., Lassmann, H., Weinshenker, B., Rodriguez, M., Parisi, J. & Lucchinetti, C. F., Aug 13 2005, In : Lancet. 366, 9485, p. 579-582 4 p.

Research output: Contribution to journalArticle

325 Scopus citations

The pathology of multiple sclerosis

Lucchinetti, C. F., Parisi, J. & Bruck, W., Feb 2005, In : Neurologic clinics. 23, 1, p. 77-105 29 p.

Research output: Contribution to journalArticle

96 Scopus citations

Tissue preconditioning may explain concentric lesions in Baló's type of multiple sclerosis

Stadelmann, C., Ludwin, S., Tabira, T., Guseo, A., Lucchinetti, C. F., Leel-Össy, L., Ordinario, A. T., Brück, W. & Lassmann, H., May 2005, In : Brain. 128, 5, p. 979-987 9 p.

Research output: Contribution to journalArticle

153 Scopus citations
6 Scopus citations
2004

A serum autoantibody marker of neuromyelitis optica: Distinction from multiple sclerosis

Lennon, P. V. A., Wingerchuk, D. M., Kryzer, T. J., Pittock, S. J., Lucchinetti, C. F., Fujihara, K., Nakashima, I. & Weinshenker, B. G., Dec 11 2004, In : Lancet. 364, 9451, p. 2106-2112 7 p.

Research output: Contribution to journalArticle

2160 Scopus citations

Bright red nuclei

Pittock, S. J., Weinshenker, B. G. & Lucchinetti, C. F., Feb 24 2004, In : Neurology. 62, 4, 1 p.

Research output: Contribution to journalArticle

Open Access

Expression of Chemokine Receptors CCR1 and CCR5 Reflects Differential Activation of Mononuclear Phagocytes in Pattern II and Pattern III Multiple Sclerosis Lesions

Mahad, D. J., Trebst, C., Kivisäkk, P., Staugaitis, S. M., Tucky, B., Wei, T., Lucchinetti, C. F., Lassmann, H. & Ransohoff, R. M., Mar 2004, In : Journal of Neuropathology and Experimental Neurology. 63, 3, p. 262-273 12 p.

Research output: Contribution to journalArticle

Open Access
54 Scopus citations

Expression of Major Histocompatibility Complex Class I Molecules on the Different Cell Types in Multiple Sclerosis Lesions

Höftberger, R., Aboul-Enein, F., Brueck, W., Lucchinetti, C., Rodriguez, M., Schmidbauer, M., Jellinger, K. & Lassmann, H., Jan 2004, In : Brain Pathology. 14, 1, p. 43-50 8 p.

Research output: Contribution to journalArticle

170 Scopus citations
2003

Anti-neuronal nuclear autoantibody type 2: Paraneoplastic accompaniments

Pittock, S. J., Lucchinetti, C. F. & Lennon, V. A., May 1 2003, In : Annals of neurology. 53, 5, p. 580-587 8 p.

Research output: Contribution to journalArticle

190 Scopus citations

CC chemokine receptor 8 in the central nervous system is associated with phagocytic macrophages

Trebst, C., Staugaitis, S. M., Kivisäkk, P., Mahad, D., Cathcart, M. K., Tucky, B., Wei, T., Rani, M. R. S., Horuk, R., Aldape, K. D., Pardo, C. A., Lucchinetti, C. F., Lassmann, H. & Ransohoff, R. M., Feb 1 2003, In : American Journal of Pathology. 162, 2, p. 427-438 12 p.

Research output: Contribution to journalArticle

47 Scopus citations

Chapter 7 Pathology and Pathogenesis of Multiple Sclerosis

Lucchinetti, C. F., Brück, W. & Lassmann, H., Dec 1 2003, In : Blue Books of Practical Neurology. 27, C, p. 93-113 21 p.

Research output: Contribution to journalArticle

2 Scopus citations

Preferential loss of myelin-associated glycoprotein reflects hypoxia-like white matter damage in stroke and inflammatory brain diseases

Aboul-Enein, F., Rauschka, H., Kornek, B., Stadelmann, C., Stefferl, A., Brück, W., Lucchinetti, C., Schmidbauer, M., Jellinger, K. & Lassmann, H., Jan 1 2003, In : Journal of Neuropathology and Experimental Neurology. 62, 1, p. 25-33 9 p.

Research output: Contribution to journalArticle

Open Access
218 Scopus citations
2002

Activity of a newly identified serine protease in CNS demyelination

Scarisbrick, I. A., Blaber, S. I., Lucchinetti, C. F., Genain, C. P., Blaber, M. & Rodriguez, M., Jan 1 2002, In : Brain. 125, 6, p. 1283-1296 14 p.

Research output: Contribution to journalArticle

Open Access
112 Scopus citations

A role for humoral mechanisms in the pathogenesis of Devic's neuromyelitis optica

Lucchinetti, C. F., Mandler, R. N., McGavern, D., Bruck, W., Gleich, G., Ransohoff, R. M., Trebst, C., Weinshenker, B., Wingerchuk, D., Parisi, J. E. & Lassmann, H., 2002, In : Brain. 125, 7, p. 1450-1461 12 p.

Research output: Contribution to journalArticle

Open Access
885 Scopus citations

Predictors of short-term disease activity following a first clinical demyelinating event: Analysis of the CHAMPS placebo group

O'Connor, P., Fleming, P., Gray, T., Jacobs, L., Miller, C., Munschauer, F., Kinkel, R. P., Bolibrush, D., Cohen, J., Freedman, M., Webb, U., Rabinowicz, H., Metz, L. M., Patry, D., Yeung, M., Peters, S., Hashimoto, S., Morrison, W., Oger, J., Panitch, H. & 169 others, Costello, K., Bever, C., Stuart, W., Court, D., Stuart, D., Tornatore, C., Bartlett, D., Richert, J., Duquette, P., Dubois, R., Bernier, G., Scott, T., Pappert, L., Brillman, J., Felton, W., Anderson, T., Astruc, J., Rose, J., Kline, J., Burns, J., Murray, T., Weldon, P., Bhan, V., Maxner, C. E., Wall, M., Vining, L., Grabowski, T., Apatoff, B., Orapello, C., Friedman, J., Galetta, S., Pfohl, D., Liu, G., Rice, G., Bental, T., Mandalfino, P., Eggenberger, E., Snider, D., Kaufman, D., Guarnaccia, J., Shepard, M., Goldstein, J., Reiss, M., Carter, E., Glista, G., Rolak, L., Scheller, L., Jacobson, D., Warner, J., Goodman, A., Petrie, M., Mattson, D., Karlin, K., Wallin, A., Stefoski, D., Brod, S., Cerretta, E., Wolinsky, J., Arnold, D., Arnoutelis, R., Durcan, L., Kupersmith, M., Cappolino, L., Herbert, J., Rosenberg, J., McHugh, D., Blumenfeld, A., Smith, C., Kuder, D., Hamilton, S., Thurston, S., McGee, J., O'Bannon, J., Kaufman, M., Butler, M., Putnam, S., Rammohan, K., Siffort, A., Lynn, J., Selhorst, J., Holzemer, E., Hayat, G., Tselis, A., Coon, C., Lisak, R., Wray, S., Sexton, P., Lehrich, J., Cook, S., Jotkowitz, A., Bansil, S., Newman, N., Brown, J., Pennell, P., Gilmore, J., Carter, J., Buckner, J., Caselli, R., Kerson, L., Camasso, M., Donneief, G., Cooper, J., Richardson, B., Kung, C., Goodwin, J., Johnson, T., Gulati, A., Hedges, T., Yardley, C., Tran, T., Brown, W., Ehrenberg, B., Horowitz, S., Bonnett, A., Burger, R., Javerbaum, J., Griffin, C., Whaley, R. J., Jeffery, D., Jackson, S. E., Bastings, E., Kasper, L., Ryan, K., Bernat, J., Mass, M., Cooper Hanel, S., Bourdette, D., Guy, J., Wilson, M., Greer, M., Lucchinetti, C., Botten, M., Noseworthy, J., Walker, A., Muntz, B., Tyor, W., Simon, J., Meyer, M., Leek, R., Gustafson, C., Singel, D., Quandt, B., Miller, D. E., Coombs, B., Cajade-Law, A., Lajaunie, M., Escott, E., Miller, A., Vollmer, T., Brownscheidle, C., Murray, T. J., Antel, J., Myers, L., Birnbaum, G., Reingold, S., Burde, R., Sibley, W., Ware, J., Blanchard, N., Lloyd, K., Park, H., Sandrock, A., Simonian, N., Slasor, P., Votruba, F., White, K., Beck, R. W., Chandler, D. L. & Cole, S., Oct 2002, In : Multiple Sclerosis. 8, 5, p. 405-409 5 p.

Research output: Contribution to journalArticle

11 Scopus citations

Proposed diagnostic criteria and nosology of acute transverse myelitis

Barnes, G., Benjamin, S., Bowen, J. D., Cutter, N., De Lateur, B. J., Dietrich, W. D., Dowling, M. M., Griffin, J. W., Hummers, L., Irani, D., Jorens, P. G., Kaplin, A. I., Katz, J. D., Kerr, D. A., Krishnan, C., Levy, C. E., Lucchinetti, C., Lynn, D. J., Mandler, R. N., McArthur, J. C. & 11 others, McDonald, J. W., Morrison, L., Pardo-Villamizar, C., Pidcock, F. S., Ransohoff, R., Roos, K. L., Trovato, M. K., Vollmer, T. L., Wegener, S. T., Weinshenker, B. G. & Wingerchuk, D. M., Aug 27 2002, In : Neurology. 59, 4, p. 499-505 7 p.

Research output: Contribution to journalArticle

517 Scopus citations
2001

A longitudinal MRI study of histopathologically defined hypointense multiple sclerosis lesions

Bitsch, A., Kuhlmann, T., Stadelmann, C., Lassmann, H., Lucchinetti, C. & Brück, W., Jun 23 2001, In : Annals of neurology. 49, 6, p. 793-796 4 p.

Research output: Contribution to journalArticle

159 Scopus citations
2000

Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination

Lucchinetti, C., Brück, W., Parisi, J., Scheithauer, B., Rodriguez, M. & Lassmann, H., Jun 30 2000, In : Annals of neurology. 47, 6, p. 707-717 11 p.

Research output: Contribution to journalArticle

2353 Scopus citations
1999

A quantitative analysis of oligodendrocytes in multiple sclerosis lesions. A study of 113 cases

Lucchinetti, C., Brück, W., Parisi, J., Scheithauer, B., Rodriguez, M. & Lassmann, H., Dec 1 1999, In : Brain. 122, 12, p. 2279-2295 17 p.

Research output: Contribution to journalArticle

363 Scopus citations

A randomized trial of plasma exchange in acute central nervous system inflammatory demyelinating disease

Weinshenker, B. G., O'Brien, P. C., Petterson, T. M., Noseworthy, J. H., Lucchinetti, C. F., Dodick, D. W., Pineda, A. A., Stevens, L. N. & Rodriguez, M., 1999, In : Annals of neurology. 46, 6, p. 878-886 9 p.

Research output: Contribution to journalArticle

632 Scopus citations

Bcl-2-expressing oligodendrocytes in multiple sclerosis lesions

Kuhlmann, T., Lucchinetti, C., Zettl, U. K., Bitsch, A., Lassmann, H. & Brück, W., Jan 1 1999, In : Glia. 28, 1, p. 34-39 6 p.

Research output: Contribution to journalArticle

47 Scopus citations

Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients

Sørensen, T. L., Tani, M., Jensen, J., Pierce, V., Lucchinetti, C., Folcik, V. A., Qin, S., Rottman, J., Sellebjerg, F., Strieter, R. M., Frederiksen, J. L. & Ransohoff, R. M., Mar 1999, In : Journal of Clinical Investigation. 103, 6, p. 807-815 9 p.

Research output: Contribution to journalArticle

Open Access
850 Scopus citations

Role of the blink reflex in the evaluation of sensory neuronopathy

Auger, R. G., Windebank, A. J., Lucchinetti, C. F. & Chalk, C. H., Jul 22 1999, In : Neurology. 53, 2, p. 407-408 2 p.

Research output: Contribution to journalArticle

36 Scopus citations
1998

Failure of treatment with Linomide or oral myelin tolerization to ameliorate demyelination in a viral model of multiple sclerosis

Drescher, K. M., Rivera-Quinones, C., Lucchinetti, C. F. & Rodriguez, M., Aug 1 1998, In : Journal of neuroimmunology. 88, 1-2, p. 111-119 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Paraneoplastic and oncologic profiles of patients seropositive for type 1 antineuronal nuclear autoantibodies

Lucchinetti, C. F., Kimmel, D. W. & Lennon, V. A., Mar 1998, In : Neurology. 50, 3, p. 652-657 6 p.

Research output: Contribution to journalArticle

379 Scopus citations

Retinocochleocerebral vasculopathy

Petty, G. W., Engel, A. G., Younge, B. R., Duffy, J., Yanagihara, T., Lucchinetti, C. F., Bartleson, J. D., Parisi, J. E., Kasperbauer, J. L. & Rodriguez, M., Jan 1 1998, In : Medicine. 77, 1, p. 12-40 29 p.

Research output: Contribution to journalArticle

113 Scopus citations
1997

5-Fluorouracil and levamisole exacerbate demyelination in susceptible mice infected with Theiler's virus

Lucchinetti, C. F., Kimmel, D. W., Pavelko, K. & Rodriguez, M., Sep 1997, In : Experimental Neurology. 147, 1, p. 123-129 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

Promotion of endogeneous remyelination in multiple sclerosis

Lucchinetti, C. F., Noseworthy, J. H. & Rodriguez, M., Apr 1997, In : Multiple Sclerosis. 3, 2, p. 71-75 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Remyelination in multiple sclerosis

Lassmann, H., Brück, W., Lucchinetti, C. & Rodriguez, M., Apr 1997, In : Multiple Sclerosis. 3, 2, p. 133-136 4 p.

Research output: Contribution to journalArticle

145 Scopus citations