• 20869 Citations
  • 82 Scopus h-Index
1976 …2020

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A 1998 status report on orthopedic gene therapy

Evans, C. H., Ghivizzani, S. C. & Robbins, P. D., Jan 1 1998, In : Current Opinion in Orthopaedics. 9, 6, p. 75-80 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Ability of recombinant human bone morphogenetic protein 2 to enhance bone healing in the presence of tobramycin: Evaluation in a rat segmental defect model

Glatt, V., Kwong, F. N., Park, K., Parry, N., Griffin, D., Vrahas, M., Evans, C. H. & Harris, M., Nov 1 2009, In : Journal of orthopaedic trauma. 23, 10, p. 693-701 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

Accelerated healing of the rat Achilles tendon in response to autologous conditioned serum

Majewski, M., Ochsner, P. E., Liu, F., Flückiger, R. & Evans, C. H., Dec 2 2009, In : American Journal of Sports Medicine. 37, 11, p. 2117-2125 9 p.

Research output: Contribution to journalArticle

58 Scopus citations

A comparative study of the inhibitory effects of interleukin-1 receptor antagonist following administration as a recombinant protein or by gene transfer.

Gouze, J. N., Gouze, E., Palmer, G. D., Liew, V. S., Pascher, A., Betz, O. B., Thornhill, T. S., Evans, C. H., Grodzinsky, A. J. & Ghivizzani, S. C., 2003, In : Arthritis research & therapy. 5, 5, p. R301-309

Research output: Contribution to journalArticle

38 Scopus citations

Adenoviral gene transfer of a single-chain IL-23 induces psoriatic arthritis–like symptoms in NOD mice

Flores, R. R., Carbo, L., Kim, E., Van Meter, M., De Padilla, C. M. L., Zhao, J., Colangelo, D., Yousefzadeh, M. J., Angelini, L. A., Zhang, L., Pola, E., Vo, N., Evans, C. H., Gambotto, A., Niedernhofer, L. J. & Robbins, P. D., Aug 1 2019, In : FASEB Journal. 33, 8, p. 9505-9515 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Adenoviral mediated delivery of FAS ligand to arthritic joints causes extensive apoptosis in the synovial lining

Yao, Q., Glorioso, J. C., Evans, C. H., Robbins, P. D., Kovesdi, I., Oligino, T. J. & Ghivizzani, S. C., 2000, In : Journal of Gene Medicine. 2, 3, p. 210-219 10 p.

Research output: Contribution to journalArticle

47 Scopus citations

Adenoviral transduction of human osteoblastic cell cultures. A new perspective for gene therapy of bone diseases

Baltzer, A. W. A., Whalen, J. D., Stefanovic-Racic, M., Ziran, B., Robbins, P. D. & Evans, C. H., Oct 1999, In : Acta Orthopaedica Scandinavica. 70, 5, p. 419-424 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

Adenoviral transfer of the viral IL-10 gene periarticularly to mouse paws suppresses development of collagen-induced arthritis in both injected and uninjected paws

Whalen, J. D., Lechman, E. L., Carlos, C. A., Weiss, K., Kovesdi, I., Glorioso, J. C., Robbins, P. D. & Evans, C. H., Mar 15 1999, In : Journal of Immunology. 162, 6, p. 3625-3632 8 p.

Research output: Contribution to journalArticle

184 Scopus citations

Adenovirus-mediated direct gene therapy with bone morphogenetic protein-2 produces bone

Musgrave, D. S., Bosch, P., Ghivizzani, S., Robbins, P. D., Evans, C. H. & Huard, J., Jun 1 1999, In : Bone. 24, 6, p. 541-547 7 p.

Research output: Contribution to journalArticle

214 Scopus citations

Adenovirus-mediated gene transfer of glutamine: Fructose-6-phosphate amidotransferase antagonizes the effects of interluekin-1β on rat chondrocytes

Gouze, J. N., Gouze, E., Palmer, G. D., Kaneto, H., Ghivizzani, S. C., Grodzinsky, A. J. & Evans, C. H., Mar 2004, In : Osteoarthritis and Cartilage. 12, 3, p. 217-224 8 p.

Research output: Contribution to journalArticle

26 Scopus citations

Adenovirus-mediated gene transfer of insulin-like growth factor 1 stimulates proteoglycan synthesis in rabbit joints

Mi, Z., Ghivizzani, S. C., Lechman, E. R., Jaffurs, D., Glorioso, J. C., Evans, C. H. & Robbins, P. D., Nov 22 2000, In : Arthritis and rheumatism. 43, 11, p. 2563-2570 8 p.

Research output: Contribution to journalArticle

97 Scopus citations

Adenovirus-mediated gene transfer to nucleus pulposus cells implications for the treatment of intervertebral disc degeneration

Nishida, K., Kang, J. D., Suh, J. K., Robbins, P. D., Evans, C. H. & Gilbertson, L. G., Nov 15 1998, In : Spine. 23, 22, p. 2437-2443 7 p.

Research output: Contribution to journalArticle

133 Scopus citations

Advances in regenerative orthopedics

Evans, C. H., Nov 2013, In : Mayo Clinic proceedings. 88, 11, p. 1323-1339 17 p.

Research output: Contribution to journalArticle

45 Scopus citations

Adverse effects of adenovirus-mediated gene transfer of human transforming growth factor beta 1 into rabbit knees.

Mi, Z., Ghivizzani, S. C., Lechman, E., Glorioso, J. C., Evans, C. H. & Robbins, P. D., 2003, In : Arthritis research & therapy. 5, 3, p. R132-139

Research output: Contribution to journalArticle

92 Scopus citations

A gene therapy approach to accelerating bone healing. Evaluation of gene expression in a New Zealand white rabbit model.

Baltzer, A. W., Lattermann, C., Whalen, J. D., Braunstein, S., Robbins, P. D. & Evans, C. H., 1999, In : Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA. 7, 3, p. 197-202 6 p.

Research output: Contribution to journalArticle

70 Scopus citations
6 Scopus citations

Altered patterns of protein phosphorylation in articular chondrocytes treated with interleukin-1 or synovial cytokines

Hulkower, K. I., Georgescu, H. I. & Evans, C. H., Nov 6 1989, In : FEBS Letters. 257, 2, p. 228-232 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

Altered relative expression of BMPs and BMP inhibitors in cartilaginous areas of human fractures progressing towards nonunion

Kwong, F. N. K., Hoyland, J. A., Freemont, A. J. & Evans, C. H., Jun 1 2009, In : Journal of Orthopaedic Research. 27, 6, p. 752-757 6 p.

Research output: Contribution to journalArticle

44 Scopus citations

An evaluation of fluorometric proteinase assays which employ fluorescamine

Evans, C. H. & Ridella, J. D., Nov 1 1984, In : Analytical Biochemistry. 142, 2, p. 411-420 10 p.

Research output: Contribution to journalArticle

18 Scopus citations

An Improved, Chemically Modified RNA Encoding BMP-2 Enhances Osteogenesis in Vitro and in Vivo

Zhang, W., De La Vega, R. E., Coenen, M. J., Müller, S. A., Peniche Silva, C. J., Aneja, M. K., Plank, C., Van Griensven, M., Evans, C. H. & Balmayor, E. R., Jan 1 2019, In : Tissue Engineering - Part A. 25, 1-2, p. 131-144 14 p.

Research output: Contribution to journalArticle

5 Scopus citations

An inverse relationship between mammalian lifespan and cartilage cellularity

Evans, C. H., 1983, In : Experimental Gerontology. 18, 2, p. 137-138 2 p.

Research output: Contribution to journalArticle

5 Scopus citations

Application of ferrography to the study of wear and arthritis in human joints

Evans, C. H., Oct 1 1983, In : Wear. 90, 2, p. 281-292 12 p.

Research output: Contribution to journalArticle

12 Scopus citations

Application of structural rigidity analysis to assess fidelity of healed fractures in rat femurs with critical defects

Nazarian, A., Pezzella, L., Tseng, A., Baldassarri, S., Zurakowski, D., Evans, C. H. & Snyder, B. D., May 1 2010, In : Calcified Tissue International. 86, 5, p. 397-403 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Approaches to enhancing the retroviral transduction of human synoviocytes

Del Vecchio, M. A., Georgescu, H. I., McCormack, J. E., Robbins, P. D. & Evans, C. H., 2001, In : Arthritis Research. 3, 4, p. 259-263 5 p.

Research output: Contribution to journalArticle

15 Scopus citations

Approaches to paramagnetic separations in biology and medicine

Evans, C. H., Russell, A. P. & Westcott, V. C., Jan 1 1989, In : Particulate Science and Technology. 7, 1-2, p. 97-109 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

A preliminary ferrographic survey of the wear particles in human synovial fluid

Evans, C. H., Mears, D. C. & Mcknight, J. L., Jul 1981, In : Arthritis & Rheumatism. 24, 7, p. 912-918 7 p.

Research output: Contribution to journalArticle

35 Scopus citations

Arginase Treatment Prevents the Recovery of Canine Lymphoma and Osteosarcoma Cells Resistant to the Toxic Effects of Prolonged Arginine Deprivation

Wells, J. W., Evans, C. H., Scott, M. C., Rütgen, B. C., O'Brien, T. D., Modiano, J. F., Cvetkovic, G. & Tepic, S., Jan 30 2013, In : PloS one. 8, 1, e54464.

Research output: Contribution to journalArticle

4 Scopus citations

Arthritis gene therapy

Robbins, P. D. & Evans, C. H., Jan 1 1999, In : Drugs of Today. 35, 4-5, p. 353-360 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Arthritis Gene Therapy Approved in Korea

Evans, C. H., Ghivizzani, S. C. & Robbins, P. D., Jan 15 2018, In : Journal of the American Academy of Orthopaedic Surgeons. 26, 2, p. e36-e38

Research output: Contribution to journalArticle

7 Scopus citations

Arthritis gene therapy is becoming a reality

Evans, C. H., Ghivizzani, S. C. & Robbins, P. D., May 9 2018, (Accepted/In press) In : Nature Reviews Rheumatology. p. 1-2 2 p.

Research output: Contribution to journalArticle

7 Scopus citations

Arthritis gene therapy's first death

Evans, C. H., Ghivizzani, S. C. & Robbins, P. D., Feb 27 2008, In : Arthritis Research and Therapy. 10, 3, 110.

Research output: Contribution to journalArticle

72 Scopus citations

Articular chondrocytes synthesize nitric oxide in response to cytokines and lipopolysaccharide

Stadler, J., Stefanovic-Racic, M., Billiar, T. R., Curran, R. D., McIntyre, L. A., Georgescu, H. I., Simmons, R. L. & Evans, C. H., Jan 1 1991, In : Journal of Immunology. 147, 11, p. 3915-3920 6 p.

Research output: Contribution to journalArticle

422 Scopus citations

Articular responses to purified cartilage proteoglycans

Boniface, R. J., Cain, P. R. & Evans, C. H., Feb 1988, In : Arthritis & Rheumatism. 31, 2, p. 258-266 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

A simple, lanthanide-based method to enhance the transduction efficiency of adenovirus vectors

Palmer, G. D., Stoddart, M. J., Gouze, E., Gouze, J. N., Ghivizzani, S. C., Porter, R. M. & Evans, C. H., Mar 1 2008, In : Gene Therapy. 15, 5, p. 357-363 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

Autologous bone grafting on steroids: Preliminary clinical results. A novel treatment for nonunions and segmental bone defects

Miller, M. A., Ivkovic, A., Porter, R., Harris, M. B., Estok, D. M., Smith, R. M., Evans, C. H. & Vrahas, M. S., Apr 1 2011, In : International Orthopaedics. 35, 4, p. 599-605 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

Barriers and strategies for the clinical translation of advanced orthopaedic tissue engineering protocols

Madry, H., Alini, M., Stoddart, M. J., Evans, C., Miclau, T. & Steiner, S., May 6 2014, In : European Cells and Materials. 27, SUPPL, p. 17-21 5 p.

Research output: Contribution to journalArticle

Open Access
22 Scopus citations
7 Scopus citations

Biologics for tendon repair

Docheva, D., Müller, S. A., Majewski, M. & Evans, C. H., Apr 1 2015, In : Advanced Drug Delivery Reviews. 84, p. 222-239 18 p.

Research output: Contribution to journalArticle

205 Scopus citations

Blocking cytokines with genes

Evans, C. H., Ghivizzani, S. C. & Robbins, P. D., Jul 1998, In : Journal of Leukocyte Biology. 64, 1, p. 55-61 7 p.

Research output: Contribution to journalArticle

27 Scopus citations

BMP12 and BMP13 gene transfer induce ligamentogenic differentiation in mesenchymal progenitor and anterior cruciate ligament cells

Haddad-Weber, M., Prager, P., Kunz, M., Seefried, L., Jakob, F., Murray, M. M., Evans, C. H., Nöth, U. & Steinert, A. F., Jul 2010, In : Cytotherapy. 12, 4, p. 505-513 9 p.

Research output: Contribution to journalArticle

61 Scopus citations

Breakout session 8: Ligament and tendon

Hart, D. A. & Evans, C. H., Jan 1 2000, In : Clinical orthopaedics and related research. 379 SUPPL., p. S260-S261

Research output: Contribution to journalArticle

6 Scopus citations

Breakout session 9: Gene therapy for rheumatoid arthritis

Ghivizzani, S. C. & Evans, C. H., 2000, In : Clinical Orthopaedics and Related Research. 379 SUPPL.

Research output: Contribution to journalArticle

Breakout session 9: Gene therapy for rheumatoid arthritis

Ghivizzani, S. C. & Evans, C. H., Jan 1 2000, In : Clinical orthopaedics and related research. 379 SUPPL., p. S308-S310

Research output: Contribution to journalArticle

Catering to chondrocytes

Evans, C. H., Nov 28 2018, In : Science Translational Medicine. 10, 469, eaav7043.

Research output: Contribution to journalArticle

2 Scopus citations

Cellular mechanisms of hydrolytic enzyme release in osteoarthritis

Evans, C. H., 1981, In : Seminars in Arthritis and Rheumatism. 11, 1 SUPPL. 1, p. 93-95 3 p.

Research output: Contribution to journalArticle

14 Scopus citations

Characterisation of chondrocyte activation in response to cytokines synthesised by a synovial cell line

Sung, K., Mendelow, D., Georgescu, H. I. & Evans, C. H., Sep 16 1988, In : BBA - Molecular Cell Research. 971, 2, p. 148-156 9 p.

Research output: Contribution to journalArticle

35 Scopus citations

Characterization and utilization of mesenchymal progenitor cells recovered with the Reamer-Irrigator-Aspirator

Porter, R. M., Ivkovic, A., Wells, J., Glatt, V., Harris, M. B., Vrahas, M. S. & Evans, C., Jul 1 2008, In : European Cells and Materials. 16, SUPPL.2, 1 p.

Research output: Contribution to journalArticle

2 Scopus citations

Characterization of monoclonal antibodies against rabbit CD44: Evidence of a role for CD44 in modulating synoviocyte metabolism

Galea-Lauri, J., Wilkinson, J. M. & Evans, C. H., Oct 1993, In : Molecular Immunology. 30, 15, p. 1383-1392 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Chondrocyte activation by a putative interleukin-1 derived from lapine polymorphonuclear leukocytes

Watanabe, S., Georgescu, H. I., Kuhns, D. B. & Evans, C. H., Apr 1989, In : Archives of Biochemistry and Biophysics. 270, 1, p. 69-76 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Chondrocyte activation by interleukin-1: Analysis of the synergistic properties of fibroblast growth factor and phorbol myristate acetate

Bandara, G., Lin, C. W., Georgescu, H. I., Mendelow, D. & Evans, C. H., Nov 1 1989, In : Archives of Biochemistry and Biophysics. 274, 2, p. 539-547 9 p.

Research output: Contribution to journalArticle

33 Scopus citations