• 20795 Citations
  • 82 Scopus h-Index
1976 …2020

Research output per year

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Research Output

1996

Gene transfer to the rabbit patellar tendon: Potential for genetic enhancement of tendon and ligament healing

Gerich, T. G., Kang, R., Fu, F. H., Robbins, P. D. & Evans, C. H., Dec 1 1996, In : Gene Therapy. 3, 12, p. 1089-1093 5 p.

Research output: Contribution to journalArticle

88 Scopus citations

Herniated lumbar intervertebral discs spontaneously produce matrix metalloproteinases, nitric oxide, interleukin-6, and prostaglandin E2

Kang, J. D., Georgescu, H. I., McIntyre-Larkin, L., Stefanovic-Racic, M., Donaldson, W. F. & Evans, C. H., Feb 1 1996, In : Spine. 21, 3, p. 271-277 7 p.

Research output: Contribution to journalArticle

517 Scopus citations

Interleukin-1 receptor antagonist suppresses neurotrophin response in injured rat brain

Dekosky, S. T., Styren, S. D., O'Malley, M. E., Goss, J. R., Kochanek, P., Marion, D., Evans, C. H. & Robbins, P. D., Feb 14 1996, In : Annals of neurology. 39, 1, p. 123-127 5 p.

Research output: Contribution to journalArticle

90 Scopus citations

Neurophysiologic Changes in Lumbar Nerve Root Inflammation in the Rat after Treatment with Cytokine Inhibitors: Evidence for a Role of Interleukin-1

Wehling, P., Cleveland, S. J., Heininger, K., Schulitz, K. P., Reinecke, J. & Evans, C. H., Apr 15 1996, In : Spine. 21, 8, p. 931-935 5 p.

Research output: Contribution to journalArticle

27 Scopus citations

Nitric oxide and cartilage metabolism

Evans, C. H., Watkins, S. C. & Stefanović-Račić, M., Sep 18 1996, In : Methods in enzymology. 269, p. 75-88 14 p.

Research output: Contribution to journalArticle

60 Scopus citations

Nitric oxide in arthritis

Evans, C. H. & Stefanovic-Racic, M., Aug 1996, In : Methods: A Companion to Methods in Enzymology. 10, 1, p. 38-42 5 p.

Research output: Contribution to journalArticle

27 Scopus citations

Patenting gene therapy for arthritis

Evans, C. H., Hand, M. & Robbins, P. D., Jan 1 1996, In : Expert Opinion on Therapeutic Patents. 6, 3, p. 253-257 5 p.

Research output: Contribution to journalReview article

1 Scopus citations

Pathways to gene therapy in rheumatoid arthritis

Evans, C. H. & Robbins, P. D., Jan 1 1996, In : Current opinion in rheumatology. 8, 3, p. 230-234 5 p.

Research output: Contribution to journalReview article

43 Scopus citations

Prospects for gene therapy in sports medicine

Gerich, T. G., Fu, F. H., Robbins, P. D. & Evans, C. H., Jan 1 1996, In : Knee Surgery, Sports Traumatology, Arthroscopy. 4, 3, p. 180-187 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Prospects for treating autoimmune and inflammatory diseases by gene therapy

Robbins, P. D. & Evans, C. H., May 2 1996, In : Gene Therapy. 3, 3, p. 187-189 3 p.

Research output: Contribution to journalEditorial

29 Scopus citations

Suppression of antigen-induced arthritis in rabbits by ex vivo gene therapy

Otani, K., Nita, I., Macaulay, W., Georgescu, H. I., Robbins, P. D. & Evans, C. H., May 1 1996, In : Journal of Immunology. 156, 9, p. 3558-3562 5 p.

Research output: Contribution to journalArticle

177 Scopus citations

The promise of a new clinical trial--intra-articular IL-1 receptor antagonist.

Evans, C. H. & Robbins, P. D., Jan 1996, In : Proceedings of the Association of American Physicians. 108, 1, p. 1-5 5 p.

Research output: Contribution to journalReview article

7 Scopus citations

The role of nitric oxide in proteoglycan turnover by bovine articular cartilage organ cultures

Stefanovic-Racic, M., Morales, T. I., Taskiran, D., McIntyre, L. A. & Evans, C. H., Feb 1 1996, In : Journal of Immunology. 156, 3, p. 1213-1220 8 p.

Research output: Contribution to journalArticle

99 Scopus citations
1995

Arthritis.

Evans, C. H. & Robbins, P. D., 1995, In : Molecular and cell biology of human diseases series. 5, p. 252-260 9 p.

Research output: Contribution to journalReview article

4 Scopus citations

Comparison of the nitric oxide synthase inhibitors methylarginine and aminoguanidine as prophylactic and therapeutic agents in rat adjuvant arthritis

Stefanovic-Racic, M., Meyers, K., Meschter, C., Coffey, J. W., Hoffman, R. A. & Evans, C. H., Jan 1 1995, In : Journal of Rheumatology. 22, 10, p. 1922-1928 7 p.

Research output: Contribution to journalArticle

105 Scopus citations

Effect of growth factors on the proliferation of fibroblasts from the medial collateral and anterior cruciate ligaments

Schmidt, C. C., Georgescu, H. I., Kwoh, C. K., Blomstrom, G. L., Engle, C. P., Larkin, L. A., Evans, C. H. & Woo, S. LY., Mar 1995, In : Journal of Orthopaedic Research. 13, 2, p. 184-190 7 p.

Research output: Contribution to journalArticle

148 Scopus citations

German Gene Therapy

Evans, C. H., Jan 1 1995, In : Bio/Technology. 13, 10, 1 p.

Research output: Contribution to journalLetter

Herniated cervical intervertebral discs spontaneously produce matrix metalloproteinases, nitric oxide, interleukin-6, and prostaglandin e2

Kang, J. D., Georgescu, H. I., Mc Lntyre-Larkin, L., Stefanovic-Racic, M. & Evans, C. H., Nov 1995, In : Spine. 20, 22, p. 2373-2378 6 p.

Research output: Contribution to journalArticle

164 Scopus citations

Modulation of chondrocyte proteoglycan synthesis by endogeneously produced nitric oxide

Stefanovic-Racic, M., Taskiran, D., Georgescu, H. I. & Evans, C. H., Aug 1 1995, In : Inflammation Research. 44, 2 Supplement, p. S216-S217

Research output: Contribution to journalArticle

17 Scopus citations

Nitric oxide: What role does it play in inflammation and tissue destruction

Evans, C. H., Jan 1 1995, In : Agents and Actions Supplements. 47, p. 107-116 10 p.

Research output: Contribution to journalReview article

90 Scopus citations

Nitric oxide and its role in orthopaedic disease

Evans, C. H., Stefanovic-Racic, M. & Lancaster, J., Jan 1 1995, In : Clinical orthopaedics and related research. 312, p. 275-294 20 p.

Research output: Contribution to journalArticle

137 Scopus citations

Possible orthopaedic applications of gene therapy

Evans, C. H. & Robbins, P. D., Jan 1 1995, In : Journal of Bone and Joint Surgery - Series A. 77, 7, p. 1103-1114 12 p.

Research output: Contribution to journalReview article

175 Scopus citations

Progress toward the treatment of arthritis by gene therapy

Evans, C. H. & Robbins, P. D., Jan 1 1995, In : Annals of Medicine. 27, 5, p. 543-546 4 p.

Research output: Contribution to journalArticle

28 Scopus citations

Prolonged systemic expression of human IL-1 receptor antagonist (hIL-1ra) in mice reconstituted with hematopoietic cells transduced with a retrovirus carry/no the hIL-1ra cDNA

Boggs, S. S., Patrene, K. D., Mueller, G. M., Evans, C. H., Doughty, L. A. & Robbins, P. D., Dec 1 1995, In : Gene Therapy. 2, 9, p. 632-638 7 p.

Research output: Contribution to journalArticle

35 Scopus citations

Reply

Evans, C. H. & Stefanovic‐Racic, M., 1995, In : Arthritis Care and Research. 38, 10, p. 1530-1531 2 p.

Research output: Contribution to journalLetter

1 Scopus citations

Section review: Biologicals & immunologicals: Gene therapy as a treatment for rheumatoid arthritis

Evans, C. & Robbins, P., Sep 1 1995, In : Expert Opinion on Investigational Drugs. 4, 9, p. 843-852 10 p.

Research output: Contribution to journalArticle

11 Scopus citations
1994

Nitric oxide and energy production in articular chondrocytes

Stefanovic‐Racic, M., Stadler, J., Georgescu, H. I. & Evans, C. H., May 1994, In : Journal of Cellular Physiology. 159, 2, p. 274-280 7 p.

Research output: Contribution to journalArticle

68 Scopus citations

Nitric oxide and proteoglycan biosynthesis by human articular chondrocytes in alginate culture

Häuselmann, H. J., Oppliger, L., Michel, B. A., Stefanovic-Racic, M. & Evans, C. H., Oct 3 1994, In : FEBS Letters. 352, 3, p. 361-364 4 p.

Research output: Contribution to journalArticle

122 Scopus citations

Nitric-Oxide Mediates Suppression of Cartilage Proteoglycan Synthesis by Interleukin-1

Taskiran, D., Stefanovicracic, M., Georgescu, H. & Evans, C., Apr 15 1994, In : Biochemical and Biophysical Research Communications. 200, 1, p. 142-148 7 p.

Research output: Contribution to journalArticle

336 Scopus citations

Nitric oxide synthesis and its regulation by rabbit synoviocytes

Stefanovic-Racic, M., Stadler, J., Georgescu, H. I. & Evans, C. H., Jan 1 1994, In : Journal of Rheumatology. 21, 10, p. 1892-1898 7 p.

Research output: Contribution to journalArticle

68 Scopus citations

N‐Monomethyl arginine, an inhibitor of nitric oxide synthase, suppresses the development of adjuvant arthritis in rats

Stefanovic‐Racic, M., Meyers, K., Meschter, C., Coffey, J. W., Hoffman, R. A. & Evans, C. H., Jul 1994, In : Arthritis & Rheumatism. 37, 7, p. 1062-1069 8 p.

Research output: Contribution to journalArticle

202 Scopus citations

Particle‐induced synthesis of collagenase by synovial fibroblasts: An immunocytochemical study

Greis, P. E., Georgescu, H. I., Fu, F. H. & Evans, C. H., Mar 1994, In : Journal of Orthopaedic Research. 12, 2, p. 286-293 8 p.

Research output: Contribution to journalArticle

35 Scopus citations

PERSPEKTIVEN DER GENTHERAPIE BEI RHEUMATISCHEN UND DEGENERATIVEN ERKRANKUNGEN DER WIRBELSAULE UND DER GELENKE

Translated title of the contribution: Prospectives of gentherapy in orthopaedic diseases of the spine and the jointsEvans, C. H., Wehling, P. & Reinecke, J., Dec 1 1994, In : Zeitschrift fur Orthopadie und Ihre Grenzgebiete. 132, 6, p. 449-452 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

Prospects for treating arthritis by gene therapy

Evans, C. & Robbins, P. D., Jan 1 1994, In : Journal of Rheumatology. 21, 5, p. 779-782 4 p.

Research output: Contribution to journalEditorial

52 Scopus citations

Retroviral Vectors for Use in Human Gene Therapy for Cancer, Gaucher Disease, and Arthritis

ROBBINS, PAUL. D., TAHARA, HIDEAKI., MUELLER, GUNHILD., HUNG, GREG., BAHNSON, ALFRED., ZITVOGEL, LAURENCE., GALEA‐LAURI, JOANNA., OHASHI, TOYA., PATRENE, KEN., BOGGS, SALLIE. S., EVANS, CHRISTOPHER. H., BARRANGER, JOHN. A. & LOTZE, MICHAEL. T., May 1994, In : Annals of the New York Academy of Sciences. 716, 1, p. 72-89 18 p.

Research output: Contribution to journalArticle

36 Scopus citations

Suppression of intra-articular responses to interleukin-1 by transfer of the interleukin-1 receptor antagonist gene to synovium

Hung, G. L., Galea-Lauri, J., Mueller, G. M., Georgescu, H. I., Larkin, L. A., Suchanek, M. K., Tindal, M. H., Robbins, P. D. & Evans, C. H., Dec 1 1994, In : Gene Therapy. 1, 1, p. 64-69 6 p.

Research output: Contribution to journalArticle

117 Scopus citations

Synovial fluid cytokine concentrations as possible prognostic indicators in the ACL-deficient knee

Cameron, M. L., Fu, F. H., Paessler, H. H., Schneider, M. & Evans, C. H., Mar 1 1994, In : Knee Surgery, Sports Traumatology, Arthroscopy. 2, 1, p. 38-44 7 p.

Research output: Contribution to journalArticle

119 Scopus citations

The interleukin-1 receptor antagonist and its delivery by gene transfer.

Evans, C. H. & Robbins, P. D., Jan 1 1994, In : Receptor. 4, 1, p. 9-15 7 p.

Research output: Contribution to journalReview article

36 Scopus citations
1993

Characterization of monoclonal antibodies against rabbit CD44: Evidence of a role for CD44 in modulating synoviocyte metabolism

Galea-Lauri, J., Wilkinson, J. M. & Evans, C. H., Oct 1993, In : Molecular Immunology. 30, 15, p. 1383-1392 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

DIE WIRKUNG VON ZYTOKINEN AUF DAS REGENERATIONSERGEBNIS KOMPRIMIERTER NERVENWURZELN UND DURCHTRENNTER PERIPHERER NERVEN

Translated title of the contribution: The effect of cytokines on regeneration of compressed nerve roots and transsected peripheral nervesWehling, P., Wirths, J. & Evans, C. H., Jan 1 1993, In : Zeitschrift fur Orthopadie und Ihre Grenzgebiete. 131, 1, p. 83-93 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

Intraarticular expression of biologically active interleukin 1-receptor-antagonist protein by ex vivo gene transfer

Bandara, G., Mueller, G. M., Galea-Lauri, J., Tindal, M. H., Georgescu, H. I., Suchanek, M. K., Hung, G. L., Glorioso, J. C., Robbins, P. D. & Evans, C. H., Nov 15 1993, In : Proceedings of the National Academy of Sciences of the United States of America. 90, 22, p. 10764-10768 5 p.

Research output: Contribution to journalArticle

267 Scopus citations

Nitric oxide and arthritis

Stefanovic‐Racic, M., Stadler, J. & Evans, C. H., Sep 1993, In : Arthritis & Rheumatism. 36, 8, p. 1036-1044 9 p.

Research output: Contribution to journalArticle

270 Scopus citations

The induction of IL-1 by freeze-dried ethylene oxide-treated bone-patellar tendon-bone allograft wear particles: An in vitro study

Silvaggio, V. J., Fu, F. H., Georgescu, H. I. & Evans, C. H., Jan 1 1993, In : Arthroscopy. 9, 1, p. 82-86 5 p.

Research output: Contribution to journalArticle

16 Scopus citations

The role of AP-1 in matrix metalloproteinase gene expression

Lin, C. W., Georgescu, H. I. & Evans, C. H., Mar 1 1993, In : Agents and Actions. 39, 1 Supplement, p. C215-C218

Research output: Contribution to journalArticle

15 Scopus citations
1992

Gene Transfer to Synoviocytes: Prospects for Gene Treatment of Arthritis

Bandara, G., Robbins, P. D., Georgescu, H. I., Mueller, G. M., Glorioso, J. C. & Evans, C. H., Apr 1992, In : DNA and Cell Biology. 11, 3, p. 227-231 5 p.

Research output: Contribution to journalArticle

121 Scopus citations

Synovial cell transplants for gene transfer to joints

Evans, C. H., Bandara, G., Mueller, G., Robbins, P., Glorioso, J. C. & Georgescu, H. I., Dec 1 1992, In : Transplantation proceedings. 24, 6, 1 p.

Research output: Contribution to journalArticle

8 Scopus citations

Synovial protein kinase C and its apparent insensitivity to interleukin‐1

HULKOWER, K. I., SAGI‐EISENBERG, R., TRAUB, L. M., GEORGESCU, H. I. & EVANS, C. H., Oct 1992, In : European Journal of Biochemistry. 209, 1, p. 81-88 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

The synovial activation of chondrocytes: evidence for complex cytokine interactions involving a possible novel factor

Bandara, G., Lin, C. W., Georgescu, H. I. & Evans, C. H., Apr 7 1992, In : BBA - Molecular Cell Research. 1134, 3, p. 309-318 10 p.

Research output: Contribution to journalArticle

30 Scopus citations

Use of an anticollagenase antibody to study synovial cell interactions with particulate material

Greis, P. E., Georgescu, H. I., Fu, F. H. & Evans, C. H., Dec 1 1992, In : ASTM Special Technical Publication. 1144, p. 200-205 6 p.

Research output: Contribution to journalConference article

1991

Articular chondrocytes synthesize nitric oxide in response to cytokines and lipopolysaccharide

Stadler, J., Stefanovic-Racic, M., Billiar, T. R., Curran, R. D., McIntyre, L. A., Georgescu, H. I., Simmons, R. L. & Evans, C. H., Jan 1 1991, In : Journal of Immunology. 147, 11, p. 3915-3920 6 p.

Research output: Contribution to journalArticle

421 Scopus citations