• 20795 Citations
  • 82 Scopus h-Index
1976 …2020

Research output per year

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Research Output

2004

Gene therapies for osteoarthritis.

Evans, C. H., Feb 2004, In : Current rheumatology reports. 6, 1, p. 31-40 10 p.

Research output: Contribution to journalReview article

27 Scopus citations

Gene therapy in the musculoskeletal system

Steinert, A. F., Palmer, G. D. & Evans, C. H., Oct 1 2004, In : Current Opinion in Orthopaedics. 15, 5, p. 318-324 7 p.

Research output: Contribution to journalReview article

3 Scopus citations

Gene transfer to the tendon-bone insertion site

Lattermann, C., Zelle, B. A., Whalen, J. D., Baltzer, A. W. A., Robbins, P. D., Niyibizi, C., Evans, C. H. & Fu, F. H., Sep 1 2004, In : Knee Surgery, Sports Traumatology, Arthroscopy. 12, 5, p. 510-515 6 p.

Research output: Contribution to journalArticle

20 Scopus citations

In vitro gene transfer to chondrocytes and synovial fibroblasts by adenoviral vectors.

Gouze, J. N., Stoddart, M. J., Gouze, E., Palmer, G. D., Ghivizzani, S. C., Grodzinsky, A. J. & Evans, C. H., 2004, In : Methods in molecular medicine. 100, p. 147-164 18 p.

Research output: Contribution to journalArticle

15 Scopus citations

On the TRAIL of an arthritis cure

Evans, C. H., May 1 2004, In : Gene Therapy. 11, 9, p. 735-736 2 p.

Research output: Contribution to journalComment/debate

6 Scopus citations

Orthopaedics: Gene therapy's dark horse

Evans, C. H., Feb 1 2004, In : Gene Therapy. 11, 4, 1 p.

Research output: Contribution to journalEditorial

8 Scopus citations

Osteoarthritis gene therapy

Evans, C. H., Gouze, J. N., Gouze, E., Robbins, P. D. & Ghivizzani, S. C., Feb 1 2004, In : Gene Therapy. 11, 4, p. 379-389 11 p.

Research output: Contribution to journalReview article

106 Scopus citations

Protective effects of IL-1Ra or vIL-10 gene transfer on a murine model of wear debris-induced osteolysis

Yang, S. Y., Wu, B., Mayton, L., Mukherjee, P., Robbins, P. D., Evans, C. H. & Wooley, P. H., Mar 1 2004, In : Gene Therapy. 11, 5, p. 483-491 9 p.

Research output: Contribution to journalArticle

73 Scopus citations

Role of NF-κB transcription factors in antiinflammatory and proinflammatory actions of mechanical signals

Agarwal, S., Deschner, J., Long, P., Verma, A., Hofman, C., Evans, C. H. & Piesco, N., Nov 1 2004, In : Arthritis and rheumatism. 50, 11, p. 3541-3548 8 p.

Research output: Contribution to journalArticle

121 Scopus citations

The 2003 Nicolas Andry award: Orthopaedic gene therapy

Evans, C. H., Ghivizzani, S. C. & Robbins, P. D., Dec 2004, In : Clinical orthopaedics and related research. 429, p. 316-329 14 p.

Research output: Contribution to journalReview article

64 Scopus citations

The effect of AdBMP-2 on ovine osteoblasts and BMSC including a comparison to human and murine cells

Blum, R., Alini, M., Evans, C., Schneider, E. & Egermann, M., Jun 1 2004, In : European Cells and Materials. 7, SUPPL.1, 1 p.

Research output: Contribution to journalArticle

1 Scopus citations
2003

A comparative study of the inhibitory effects of interleukin-1 receptor antagonist following administration as a recombinant protein or by gene transfer.

Gouze, J. N., Gouze, E., Palmer, G. D., Liew, V. S., Pascher, A., Betz, O. B., Thornhill, T. S., Evans, C. H., Grodzinsky, A. J. & Ghivizzani, S. C., 2003, In : Arthritis research & therapy. 5, 5, p. R301-309

Research output: Contribution to journalArticle

38 Scopus citations

Adverse effects of adenovirus-mediated gene transfer of human transforming growth factor beta 1 into rabbit knees.

Mi, Z., Ghivizzani, S. C., Lechman, E., Glorioso, J. C., Evans, C. H. & Robbins, P. D., 2003, In : Arthritis research & therapy. 5, 3, p. R132-139

Research output: Contribution to journalArticle

92 Scopus citations

Gene therapy for arthritis

Robbins, P. D., Evans, C. H. & Chernajovsky, Y., May 1 2003, In : Gene Therapy. 10, 10, p. 902-911 10 p.

Research output: Contribution to journalReview article

86 Scopus citations

Gene transfer to articular chondrocytes with recombinant adenovirus.

Palmer, G. D., Gouze, E., Gouze, J. N., Betz, O. B., Evans, C. H. & Ghivizzani, S. C., 2003, In : Methods in molecular biology (Clifton, N.J.). 215, p. 235-246 12 p.

Research output: Contribution to journalArticle

26 Scopus citations

Germ-line gene therapy: Can we do it, do we need it, where do we start, and where might it lead?

Evans, C. H., Jan 1 2003, Designing Our Descendants: The Promises and Perils of Genetic Modifications. Johns Hopkins University Press, Vol. 9780801881299. p. 93-101 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Scopus citations

Interleukin-1 receptor antagonist [IL-1F3]

Arend, W. P. & Evans, C. H., Jul 7 2003, The Cytokine Handbook. Elsevier Inc., p. 669-708 40 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

13 Scopus citations

Intra-articular adenoviral-mediated gene transfer of trail induces apoptosis of arthritic rabbit synovium

Yao, Q., Wang, S., Gambotto, A., Glorioso, J. C., Evans, C. H., Robbins, P. D., Ghivizzani, S. C. & Oligino, T. J., Jun 1 2003, In : Gene Therapy. 10, 12, p. 1055-1060 6 p.

Research output: Contribution to journalArticle

59 Scopus citations

Lentiviral-mediated gene delivery to synovium: Potent intra-articular expression with amplification by inflammation

Gouze, E., Pawliuk, R., Gouze, J. N., Pilapil, C., Fleet, C., Palmer, G. D., Evans, C. H., Leboulch, P. & Ghivizzani, S. C., Apr 1 2003, In : Molecular Therapy. 7, 4, p. 460-466 7 p.

Research output: Contribution to journalArticle

77 Scopus citations
2002

Delivery of plasmid DNA to articular chondrocytes via novel collagen-glycosaminoglycan matrices

Samuel, R. E., Lee, C. R., Ghivizzani, S. C., Evans, C. H., Yannas, I. V., Olsen, B. R. & Spector, M., May 1 2002, In : Human gene therapy. 13, 7, p. 791-802 12 p.

Research output: Contribution to journalArticle

61 Scopus citations

Development of gene-based therapies for cartilage repair

Palmer, G., Pascher, A., Gouze, E., Gouze, J. N., Betz, O., Spector, M., Robbins, P. D., Evans, C. H. & Ghivizzani, S. C., Dec 1 2002, In : Critical Reviews in Eukaryotic Gene Expression. 12, 4, p. 259-273 15 p.

Research output: Contribution to journalReview article

17 Scopus citations

Gene transfer approaches to the healing of bone and cartilage

Lieberman, J. R., Ghivizzani, S. C. & Evans, C. H., Jul 1 2002, In : Molecular Therapy. 6, 2, p. 141-147 7 p.

Research output: Contribution to journalReview article

98 Scopus citations

IL-1Ra and vIL-10 gene transfer using retroviral vectors ameliorates particle-associated inflammation in the murine air pouch model

Yang, S., Wu, B., Mayton, L., Evans, C. H., Robbins, P. D. & Wooley, P. H., Jan 1 2002, In : Inflammation Research. 51, 7, p. 342-350 9 p.

Research output: Contribution to journalArticle

40 Scopus citations

In vivo gene delivery to synovium by lentiviral vectors

Gouze, E., Pawliuk, R., Pilapil, C., Gouze, J. N., Fleet, C., Palmer, G. D., Evans, C. H., Leboulch, P. & Ghivizzani, S. C., Jan 1 2002, In : Molecular Therapy. 5, 4, p. 397-404 8 p.

Research output: Contribution to journalArticle

95 Scopus citations

Tendon healing: Can it be optimised?

Maffulli, N., Moller, H. D. & Evans, C. H., Oct 1 2002, In : British journal of sports medicine. 36, 5, p. 315-316 2 p.

Research output: Contribution to journalShort survey

63 Scopus citations

Treatment of experimental equine osteoarthritis by in vivo delivery of the equine interleukin-1 receptor antagonist gene

Frisbie, D. D., Ghivizzani, S. C., Robbins, P. D., Evans, C. H. & McIlwraith, C. W., Jan 1 2002, In : Gene Therapy. 9, 1, p. 12-20 9 p.

Research output: Contribution to journalArticle

248 Scopus citations

Treatment of experimental equine osteoarthritis by in vivo delivery of the equine interleukin-1 receptor antagonist gene

Frisbie, D. D., Ghivizzani, S. C., Robbins, P. D., Evans, C. H. & McIlwraith, C. W., 2002, In : Gene Therapy. 9, 1, p. 12-20 9 p.

Research output: Contribution to journalArticle

2001

Approaches to enhancing the retroviral transduction of human synoviocytes

Del Vecchio, M. A., Georgescu, H. I., McCormack, J. E., Robbins, P. D. & Evans, C. H., Jul 19 2001, In : Arthritis Research. 3, 4, p. 259-263 5 p.

Research output: Contribution to journalArticle

15 Scopus citations

Direct adenovirus-mediated insulin-like growth factor I gene transfer enhances transplant chondrocyte function

Brower-Toland, B. D., Saxer, R. A., Goodrich, L. R., Mi, Z., Robbins, P. D., Evans, C. H. & Nixon, A. J., Jan 20 2001, In : Human gene therapy. 12, 2, p. 117-129 13 p.

Research output: Contribution to journalArticle

78 Scopus citations

Direct gene delivery strategies for the treatment of rheumatoid arthritis

Ghivizzani, S. C., Oligino, T. J., Glorioso, J. C., Robbins, P. D. & Evans, C. H., Mar 1 2001, In : Drug Discovery Today. 6, 5, p. 259-267 9 p.

Research output: Contribution to journalReview article

51 Scopus citations

Effective treatment of established murine collagen-induced arthritis by systemic administration of dendritic cells genetically modified to express IL-4

Kim, S. H., Kim, S., Evans, C. H., Ghivizzani, S. C., Oligino, T. & Robbins, P. D., Mar 1 2001, In : Journal of Immunology. 166, 5, p. 3499-3505 7 p.

Research output: Contribution to journalArticle

Open Access
178 Scopus citations

Effects of cytokine gene therapy on particulate-induced inflammation in the murine air pouch

Sud, S., Yang, S. Y., Evans, C. H., Robbins, P. D. & Wooley, P. H., Dec 27 2001, In : Inflammation. 25, 6, p. 361-372 12 p.

Research output: Contribution to journalArticle

41 Scopus citations

Future of adenoviruses in the gene therapy of arthritis

Evans, C. H., Ghivizzani, S. C., Oligino, T. A. & Robbins, P. D., Apr 26 2001, In : Arthritis Research. 3, 3, p. 142-146 5 p.

Research output: Contribution to journalComment/debate

31 Scopus citations

Gene mediated insulin-like growth factor-I delivery to the synovium

Saxer, R. A., Bent, S. J., Brower-Toland, B. D., Mi, Z., Robbins, P. D., Evans, C. H. & Nixon, A. J., Sep 11 2001, In : Journal of Orthopaedic Research. 19, 5, p. 759-767 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

Gene therapy for osteoporosis: Evaluation in a murine ovariectomy model

Baltzer, A. W. A., Whalen, J. D., Wooley, P., Latterman, C., Truchan, L. M., Robbins, P. D. & Evans, C. H., Jan 1 2001, In : Gene Therapy. 8, 23, p. 1770-1776 7 p.

Research output: Contribution to journalArticle

38 Scopus citations

Gene therapy for rheumatoid arthritis

Gouze, E., Ghivizzani, S. C., Palmer, G. D., Gouze, J. N., Robbins, P. D. & Evans, C. H., Nov 1 2001, In : Expert Opinion on Biological Therapy. 1, 6, p. 971-978 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

Gene therapy for rheumatoid arthritis.

Gouze, J. N., Ghivizzani, S. C., Gouze, E., Palmer, G. D., Betz, O. B., Robbins, P. D., Evans, C. H. & Herndon, J. H., Dec 2001, In : Hand surgery : an international journal devoted to hand and upper limb surgery and related research : journal of the Asia-Pacific Federation of Societies for Surgery of the Hand. 6, 2, p. 211-219 9 p.

Research output: Contribution to journalReview article

11 Scopus citations

Gene therapy for rheumatoid arthritis.

Gouze, E., Ghivizzani, S. C., Robbins, P. D. & Evans, C. H., Feb 2001, In : Current rheumatology reports. 3, 1, p. 79-85 7 p.

Research output: Contribution to journalReview article

9 Scopus citations
4 Scopus citations

Gene transfer of p53 to arthritic joints stimulates synovial apoptosis and inhibits inflammation

Yao, Q., Wang, S., Glorioso, J. C., Evans, C. H., Robbins, P. D., Ghivizzani, S. C. & Oligino, T. J., Jan 1 2001, In : Molecular Therapy. 3, 6, p. 901-910 10 p.

Research output: Contribution to journalArticle

56 Scopus citations

Viral IL-10 gene transfer inhibits DTH responses to soluble antigens: Evidence for involvement of genetically modified dendritic cells and macrophages

Whalen, J. D., Thomson, A. W., Lu, L., Robbins, P. D. & Evans, C. H., Jan 1 2001, In : Molecular Therapy. 4, 6, p. 543-550 8 p.

Research output: Contribution to journalArticle

36 Scopus citations
2000

Adenoviral mediated delivery of FAS ligand to arthritic joints causes extensive apoptosis in the synovial lining

Yao, Q., Glorioso, J. C., Evans, C. H., Robbins, P. D., Kovesdi, I., Oligino, T. J. & Ghivizzani, S. C., Jan 1 2000, In : Journal of Gene Medicine. 2, 3, p. 210-219 10 p.

Research output: Contribution to journalArticle

47 Scopus citations

Adenovirus-mediated gene transfer of insulin-like growth factor 1 stimulates proteoglycan synthesis in rabbit joints

Mi, Z., Ghivizzani, S. C., Lechman, E. R., Jaffurs, D., Glorioso, J. C., Evans, C. H. & Robbins, P. D., Nov 22 2000, In : Arthritis and rheumatism. 43, 11, p. 2563-2570 8 p.

Research output: Contribution to journalArticle

97 Scopus citations

Aktuelle aspekte der sehnenheilung

Translated title of the contribution: New strategies for tendon healingMöller, H. D., Evans, C. H. & Maffulli, N., Mar 1 2000, In : Orthopade. 29, 3, p. 182-187 6 p.

Research output: Contribution to journalReview article

17 Scopus citations

Breakout session 8: Ligament and tendon

Hart, D. A. & Evans, C. H., Jan 1 2000, In : Clinical orthopaedics and related research. 379 SUPPL., p. S260-S261

Research output: Contribution to journalArticle

6 Scopus citations

Breakout session 9: Gene therapy for rheumatoid arthritis

Ghivizzani, S. C. & Evans, C. H., 2000, In : Clinical Orthopaedics and Related Research. 379 SUPPL.

Research output: Contribution to journalArticle

Breakout session 9: Gene therapy for rheumatoid arthritis

Ghivizzani, S. C. & Evans, C. H., Jan 1 2000, In : Clinical orthopaedics and related research. 379 SUPPL., p. S308-S310

Research output: Contribution to journalArticle

Cartilage injury and repair

Ghivizzani, S. C., Oligino, T. J., Robbins, P. D. & Evans, C. H., May 23 2000, In : Physical Medicine and Rehabilitation Clinics of North America. 11, 2, p. 289-307 19 p.

Research output: Contribution to journalReview article

48 Scopus citations

Clinical trials in the gene therapy of arthritis

Evans, C. H., Ghivizzani, S. C., Herndon, J. H., Wasko, M. C., Reinecke, J., Wehling, P. & Robbins, P. D., Jan 1 2000, In : Clinical orthopaedics and related research. 379 SUPPL., p. S300-S307

Research output: Contribution to journalArticle

74 Scopus citations

Cyclic tensile strain acts as an antagonist of IL-1β actions in chondrocytes

Xu, Z., Buckley, M. J., Evans, C. H. & Agarwal, S., Jul 1 2000, In : Journal of Immunology. 165, 1, p. 453-460 8 p.

Research output: Contribution to journalArticle

96 Scopus citations