• 20795 Citations
  • 82 Scopus h-Index
1976 …2020

Research output per year

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Research Output

2008

Characterization and utilization of mesenchymal progenitor cells recovered with the Reamer-Irrigator-Aspirator

Porter, R. M., Ivkovic, A., Wells, J., Glatt, V., Harris, M. B., Vrahas, M. S. & Evans, C., Jul 1 2008, In : European Cells and Materials. 16, SUPPL.2, 1 p.

Research output: Contribution to journalArticle

2 Scopus citations

Evaluation of adult equine bone marrow- and adipose-derived progenitor cell chondrogenesis in hydrogel cultures

Kisiday, J. D., Kopesky, P. W., Evans, C. H., Grodzinsky, A. J., Mcllwraith, C. W. & Frisbie, D. D., Mar 1 2008, In : Journal of Orthopaedic Research. 26, 3, p. 322-331 10 p.

Research output: Contribution to journalArticle

163 Scopus citations

Expedited strategies for the restoration of bone

Evans, C. H., Glatt, V., Liu, F. J., Wells, J. W., Ferreira, E., Vrahas, M. S., Harris, M. B., Ivkovic, A. & Porter, R. M., Dec 1 2008, In : European Cells and Materials. 16, SUPPL. 4, 1 p.

Research output: Contribution to journalArticle

Ex vivo adenoviral transfer of bone morphogenetic protein 12 (BMP-12) cDNA improves Achilles tendon healing in a rat model

Majewski, M., Betz, O., Ochsner, P. E., Liu, F., Porter, R. M. & Evans, C. H., Aug 13 2008, In : Gene Therapy. 15, 16, p. 1139-1146 8 p.

Research output: Contribution to journalArticle

67 Scopus citations

Gentherapie in der Knorpelregeneration

Translated title of the contribution: Gene therapy in cartilage repairPascher, A., Palmer, G., Evans, C. H., Steinert, A., Windhager, R. & Ghivizzani, S. C., Jun 16 2008, In : Sport-Orthopadie - Sport-Traumatologie. 24, 2, p. 74-77 4 p.

Research output: Contribution to journalArticle

Improving the osteogenic behavior of human mesenchymal stromal cells

Ivkovic, A., Porter, R. M., Wells, J. W. & Evans, C. H., Jul 1 2008, In : European Cells and Materials. 16, SUPPL.2, 1 p.

Research output: Contribution to journalArticle

Influence of the mechanical environment upon the healing of segmental bone defects in a rat model Studied with a Novel external fixator

Glatt, V., Matthys, R., Ivkovic, A. & Evans, C., Jul 1 2008, In : European Cells and Materials. 16, SUPPL.2, 1 p.

Research output: Contribution to journalArticle

In situ IGF-1 gene delivery to cells emerging from the injured anterior cruciate ligament

Steinert, A. F., Weber, M., Kunz, M., Palmer, G. D., Nöth, U., Evans, C. H. & Murray, M. M., Mar 1 2008, In : Biomaterials. 29, 7, p. 904-916 13 p.

Research output: Contribution to journalArticle

31 Scopus citations

Perspectives on the use of gene therapy for chronic joint diseases

Ghivizzani, S. C., Gouze, E., Gouze, J. N., Kay, J. D., Bush, M. L., Watson, R. S., Levings, P. P., Nickerson, D. M., Colahan, P. T., Robbins, P. D. & Evans, C. H., Oct 9 2008, In : Current Gene Therapy. 8, 4, p. 273-286 14 p.

Research output: Contribution to journalReview article

12 Scopus citations

Point of view

Evans, C., Jun 15 2008, In : Spine. 33, 14, 1 p.

Research output: Contribution to journalShort survey

2 Scopus citations

Pro-inflammatory cytokines inhibit chondrogenesis by human mesenchymal stem cells through NF-κB-dependent pathways

Porter, R. M., Wehling, N., Palmer, G. D., Wells, J. W., Müller, P. E. & Evans, C. H., Jul 1 2008, In : European Cells and Materials. 16, SUPPL.2, 1 p.

Research output: Contribution to journalArticle

2007

Application des techniques de thérapie génique aux maladies ostéo-articulaires

Translated title of the contribution: Gene therapy for osteoarticular disordersGouze, J. N., Evans, C. H., Ghivizzani, S. C. & Gouze, E., Mar 1 2007, In : Medecine/Sciences. 23, 3, p. 303-309 7 p.

Research output: Contribution to journalReview article

1 Scopus citations

Chordin knockdown enhances the osteogenic differentiation of human mesenchymal stem cells

Kwong, F. N. K., Richardson, S. M. & Evans, C. H., Dec 20 2007, In : Arthritis Research and Therapy. 10, 3, R65.

Research output: Contribution to journalArticle

55 Scopus citations

Delayed administration of adenoviral BMP-2 vector improves the formation of bone in osseous defects

Betz, O. B., Betz, V. M., Nazarian, A., Egermann, M., Gerstenfeld, L. C., Einhorn, T. A., Vrahas, M. S., Bouxsein, M. L. & Evans, C. H., Jul 1 2007, In : Gene Therapy. 14, 13, p. 1039-1044 6 p.

Research output: Contribution to journalArticle

87 Scopus citations

Facilitated endogenous repair: Making tissue engineering simple, practical, and economical

Evans, C. H., Palmer, G. D., Pascher, A., Porter, R., Kwong, F. N., Gouze, E., Gouze, J. N., Liu, F., Steinert, A., Betz, O., Betz, V., Vrahas, M. & Ghivizzani, S. C., Aug 1 2007, In : Tissue Engineering. 13, 8, p. 1987-1993 7 p.

Research output: Contribution to journalReview article

103 Scopus citations

Genetically enhanced engineering of meniscus tissue using ex vivo delivery of transforming growth factor-β1 complementary deoxyribonucleic acid

Steinert, A. F., Palmer, G. D., Capito, R., Hofstaetter, J. G., Pilapil, C., Ghivizzani, S. C., Spector, M. & Evans, C. H., Sep 1 2007, In : Tissue Engineering. 13, 9, p. 2227-2237 11 p.

Research output: Contribution to journalArticle

62 Scopus citations

Genetic modification of chondrocytes with insulin-like growth factor-1 enhances cartilage healing in an equine model

Goodrich, L. R., Hidaka, C., Robbins, P. D., Evans, C. H. & Nixon, A. J., May 1 2007, In : Journal of Bone and Joint Surgery - Series B. 89, 5, p. 672-685 14 p.

Research output: Contribution to journalArticle

136 Scopus citations

Healing of segmental bone defects by direct percutaneous gene delivery: Effect of vector dose

Betz, V. M., Betz, O. B., Glatt, V., Gerstenfeld, L. C., Einhorn, T. A., Bouxsein, M. L., Vrahas, M. S. & Evans, C. H., Oct 1 2007, In : Human gene therapy. 18, 10, p. 907-915 9 p.

Research output: Contribution to journalArticle

41 Scopus citations

John Hunter and the origins of modern orthopaedic research

Evans, C. H., Apr 1 2007, In : Journal of Orthopaedic Research. 25, 4, p. 556-560 5 p.

Research output: Contribution to journalArticle

10 Scopus citations

Major biological obstacles for persistent cell-based regeneration of articular cartilage

Steinert, A. F., Ghivizzani, S. C., Rethwilm, A., Tuan, R. S., Evans, C. H. & Nöth, U., Jun 5 2007, In : Arthritis Research and Therapy. 9, 213.

Research output: Contribution to journalReview article

203 Scopus citations

The facilitated endogenous repair of bone by gene transfer

Evans, C. H., Aug 1 2007, In : European Cells and Materials. 14, SUPPL.1, 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

Transgene persistence and cell turnover in the diarthrodial joint: Implications for gene therapy of chronic joint diseases

Gouze, E., Gouze, J. N., Palmer, G. D., Pilapil, C., Evans, C. H. & Ghivizzani, S. C., Jun 1 2007, In : Molecular Therapy. 15, 6, p. 1114-1120 7 p.

Research output: Contribution to journalArticle

43 Scopus citations
2006

Direct adenoviral transfer of bone morphogenetic protein-2 cDNA enhances fracture healing in osteoporotic sheep

Egermann, M., Baltzer, A. W., Adamaszek, S., Evans, C., Robbins, P., Schneider, E. & Lill, C. A., May 1 2006, In : Human gene therapy. 17, 5, p. 507-517 11 p.

Research output: Contribution to journalArticle

80 Scopus citations

Direct adenovirus-mediated IGF-I gene transduction of synovium induces persisting synovial fluid IGF-I ligand elevations

Goodrich, L. R., Brower-Toland, B. D., Warnick, L., Robbins, P. D., Evans, C. H. & Nixon, A. J., Sep 1 2006, In : Gene Therapy. 13, 17, p. 1253-1262 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Direct percutaneous gene delivery to enhance healing of segmental bone defects

Betz, O. B., Betz, V. M., Nazarian, A., Pilapil, C. G., Vrahas, M. S., Bouxsein, M. L., Gerstenfeld, L. C., Einhorn, T. A. & Evans, C. H., Feb 1 2006, In : Journal of Bone and Joint Surgery - Series A. 88, 2, p. 355-365 11 p.

Research output: Contribution to journalArticle

109 Scopus citations

Effect of BMP-2 gene transfer on bone healing in sheep

Egermann, M., Lill, C. A., Griesbeck, K., Evans, C. H., Robbins, P. D., Schneider, E. & Baltzer, A. W., Sep 1 2006, In : Gene Therapy. 13, 17, p. 1290-1299 10 p.

Research output: Contribution to journalArticle

76 Scopus citations

Gene therapeutic approaches-transfer in vivo

Evans, C. H., Gouze, E., Gouze, J. N., Robbins, P. D. & Ghivizzani, S. C., May 20 2006, In : Advanced Drug Delivery Reviews. 58, 2, p. 243-258 16 p.

Research output: Contribution to journalReview article

53 Scopus citations

Gene therapy for arthritis: What next?

Evans, C. H., Ghivizzani, S. C. & Robbins, P. D., Jun 1 2006, In : Arthritis and rheumatism. 54, 6, p. 1714-1729 16 p.

Research output: Contribution to journalReview article

51 Scopus citations

Molecular approaches to cartilage repair

Evans, C. H., Palmer, G. D., Pascher, A., Steinert, A. & Ghivizzani, S. C., Aug 1 2006, In : European Cells and Materials. 12, SUPPL.1, 1 p.

Research output: Contribution to journalArticle

Osteogenesis by human mesenchymal stem cells cultured on silk biomaterials: Comparison of adenovirus mediated gene transfer and protein delivery of BMP-2

Meinel, L., Hofmann, S., Betz, O., Fajardo, R., Merkle, H. P., Langer, R., Evans, C. H., Vunjak-Novakovic, G. & Kaplan, D. L., Oct 1 2006, In : Biomaterials. 27, 28, p. 4993-5002 10 p.

Research output: Contribution to journalArticle

145 Scopus citations

Potential biologic therapies for the intervertebral disc

Evans, C., Apr 12 2006, In : Journal of Bone and Joint Surgery - Series A. 88, SUPPL. 2, p. 95-98 4 p.

Research output: Contribution to journalArticle

73 Scopus citations

Proteomics: Applications to the study of rheumatoid arthritis and osteoarthritis

Gobezie, R., Millett, P. J., Sarracino, D. S., Evans, C. & Thornhill, T. S., Jun 2006, In : Journal of the American Academy of Orthopaedic Surgeons. 14, 6, p. 325-332 8 p.

Research output: Contribution to journalReview article

9 Scopus citations

Will arthritis gene therapy become a clinical reality?

Evans, C. H., Ghivizzani, S. C. & Robbins, P. D., Jul 1 2006, In : Nature Clinical Practice Rheumatology. 2, 7, p. 344-345 2 p.

Research output: Contribution to journalReview article

7 Scopus citations
2005

Dual transduction of insulin-like growth factor-I and interleukin-1 receptor antagonist protein controls cartilage degradation in an osteoarthritic culture model

Haupt, J. L., Frisbie, D. D., McIlwraith, C. W., Robbins, P. D., Ghivizzani, S., Evans, C. H. & Nixon, A. J., Jan 1 2005, In : Journal of Orthopaedic Research. 23, 1, p. 118-126 9 p.

Research output: Contribution to journalArticle

74 Scopus citations

Gene-induced chondrogenesis of primary mesenchymal stem cells in vitro

Palmer, G. D., Steinert, A., Pascher, A., Gouze, E., Gouze, J. N., Betz, O., Johnstone, B., Evans, C. H. & Ghivizzani, S. C., Aug 1 2005, In : Molecular Therapy. 12, 2, p. 219-228 10 p.

Research output: Contribution to journalArticle

120 Scopus citations

Gene-mediated restoration of cartilage matrix by combination insulin-like growth factor-I/interleukin-1 receptor antagonist therapy

Nixon, A. J., Haupt, J. L., Frisbie, D. D., Morisset, S. S., McIlwraith, C. W., Robbins, P. D., Evans, C. H. & Ghivizzani, S., Jan 1 2005, In : Gene Therapy. 12, 2, p. 177-186 10 p.

Research output: Contribution to journalArticle

83 Scopus citations

Gene therapy: What have we accomplished and where do we go from here?

Evans, C. H., Jan 1 2005, In : Journal of Rheumatology. 32, SUPPL. 72, p. 17-20 4 p.

Research output: Contribution to journalArticle

15 Scopus citations

Gene therapy for the treatment of musculoskeletal diseases.

Evans, C. H., Ghivizzani, S. C., Herndon, J. H. & Robbins, P. D., Jan 1 2005, In : The Journal of the American Academy of Orthopaedic Surgeons. 13, 4, p. 230-242 13 p.

Research output: Contribution to journalReview article

45 Scopus citations

Gene transfer approaches to enhancing bone healing

Betz, O., Vrahas, M., Baltzer, A., Lieberman, J. R., Robbins, P. D. & Evans, C. H., Dec 1 2005, Bone Regeneration and Repair: Biology and Clinical Applications. Humana Press, p. 157-168 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

7 Scopus citations

Gene transfer to human joints: Progress toward a gene therapy of arthritis

Evans, C. H., Robbins, P. D., Ghivizzani, S. C., Wasko, M. C., Tomaino, M. M., Kang, R., Muzzonigro, T. A., Vogt, M., Elder, E. M., Whiteside, T. L., Watkins, S. C. & Herndon, J. H., Jun 14 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 24, p. 8698-8703 6 p.

Research output: Contribution to journalArticle

155 Scopus citations

Molecular biology in orthopaedics: The advent of molecular orthopaedics

Evans, C. H. & Rosier, R. N., Nov 1 2005, In : Journal of Bone and Joint Surgery - Series A. 87, 11, p. 2550-2564 15 p.

Research output: Contribution to journalReview article

18 Scopus citations

Novel biological approaches to the intra-articular treatment of osteoarthritis

Evans, C. H., Dec 1 2005, In : BioDrugs. 19, 6, p. 355-362 8 p.

Research output: Contribution to journalReview article

37 Scopus citations

The 3rd International Meeting on Gene Therapy in Rheumatology and Orthopaedics

Evans, C. H., Ghivizzani, S. C., Gouze, E., Rediske, J. J., Schwarz, E. M. & Robbins, P. D., Dec 1 2005, In : Arthritis Research and Therapy. 7, 6, p. 273-278 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

The potential of gene therapy for fracture healing in osteoporosis

Egermann, M., Schneider, E., Evans, C. H. & Baltzer, A. W., Dec 1 2005, In : Osteoporosis International. 16, SUPPL. 2, p. S120-S128

Research output: Contribution to journalArticle

49 Scopus citations
2004

Adenovirus-mediated gene transfer of glutamine: Fructose-6-phosphate amidotransferase antagonizes the effects of interluekin-1β on rat chondrocytes

Gouze, J. N., Gouze, E., Palmer, G. D., Kaneto, H., Ghivizzani, S. C., Grodzinsky, A. J. & Evans, C. H., Mar 2004, In : Osteoarthritis and Cartilage. 12, 3, p. 217-224 8 p.

Research output: Contribution to journalArticle

26 Scopus citations

Effects of cyclic longitudinal mechanical strain and dexamethasone on osteogenic differentiation of human bone marrow stromal cells

Jagodzinski, M., Drescher, M., Zeichen, J., Hankemeier, S., Krettek, C., Bosch, U., Van Griensven, M., Martin, I. & Evans, C., Jan 1 2004, In : European Cells and Materials. 7, p. 35-41 7 p.

Research output: Contribution to journalArticle

Open Access
116 Scopus citations

Enhanced repair of the anterior cruciate ligament by in situ gene transfer: Evaluation in an in vitro model

Pascher, A., Steinert, A. F., Palmer, G. D., Betz, O., Gouze, J. N., Gouze, E., Pilapil, C., Ghivizzani, S. C., Evans, C. H. & Murray, M. M., Aug 1 2004, In : Molecular Therapy. 10, 2, p. 327-336 10 p.

Research output: Contribution to journalArticle

52 Scopus citations

Evaluation of Ad-BMP-2 for enhancing fracture healing in an infected defect fracture rabbit model

Southwood, L. L., Frisbie, D. D., Kawcak, C. E., Ghivizzani, S. C., Evans, C. H. & McIlwraith, C. W., Jan 1 2004, In : Journal of Orthopaedic Research. 22, 1, p. 66-72 7 p.

Research output: Contribution to journalArticle

89 Scopus citations

Feasibility of percutaneous gene transfer to an atrophic nonunion in a rabbit

Lattermann, C., Baltzer, A. W., Zelle, B. A., Whalen, J. D., Niyibizi, C., Robbins, P. D., Evans, C. H. & Gruen, G. S., Aug 2004, In : Clinical orthopaedics and related research. 425, p. 237-243 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Gene delivery to cartilage defects using coagulated bone marrow aspirate

Pascher, A., Palmer, G. D., Steinert, A., Oligino, T., Gouze, E., Gouze, J. N., Betz, O., Spector, M., Robbins, P. D., Evans, C. H. & Ghivizzani, S. C., Jan 1 2004, In : Gene Therapy. 11, 2, p. 133-141 9 p.

Research output: Contribution to journalArticle

82 Scopus citations