• 20795 Citations
  • 82 Scopus h-Index
1976 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

2013

Advances in regenerative orthopedics

Evans, C. H., Nov 2013, In : Mayo Clinic proceedings. 88, 11, p. 1323-1339 17 p.

Research output: Contribution to journalArticle

44 Scopus citations

An overview of underlying causes and animal models for the study of age-related degenerative disorders of the spine and synovial joints

Vo, N., Niedernhofer, L. J., Nasto, L. A., Jacobs, L., Robbins, P. D., Kang, J. & Evans, C. H., Jun 1 2013, In : Journal of Orthopaedic Research. 31, 6, p. 831-837 7 p.

Research output: Contribution to journalReview article

55 Scopus citations

Arginase Treatment Prevents the Recovery of Canine Lymphoma and Osteosarcoma Cells Resistant to the Toxic Effects of Prolonged Arginine Deprivation

Wells, J. W., Evans, C. H., Scott, M. C., Rütgen, B. C., O'Brien, T. D., Modiano, J. F., Cvetkovic, G. & Tepic, S., Jan 30 2013, In : PloS one. 8, 1, e54464.

Research output: Contribution to journalArticle

4 Scopus citations

Arthritis gene therapy and its tortuous path into the clinic

Evans, C. H., Ghivizzani, S. C. & Robbins, P. D., Apr 2013, In : Translational Research. 161, 4, p. 205-216 12 p.

Research output: Contribution to journalReview article

58 Scopus citations

Effects of Dexamethasone on Mesenchymal Stromal Cell Chondrogenesis and Aggrecanase Activity: Comparison of Agarose and Self-Assembling Peptide Scaffolds

Florine, E. M., Miller, R. E., Porter, R. M., Evans, C. H., Kurz, B. & Grodzinsky, A. J., Jan 1 2013, In : Cartilage. 4, 1, p. 63-74 12 p.

Research output: Contribution to journalArticle

30 Scopus citations

Gene therapy in articular cartilage repair

Ivkovic, A., Hudetz, D., Vukasovic, A., Porter, R. M., Pecina, M. & Evans, C. H., Jun 1 2013, Developing Insights in Cartilage Repair. Springer-Verlag London Ltd, p. 21-41 21 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Inflammatory cytokines induce a unique mineralizing phenotype in mesenchymal stem cells derived from human bone marrow

Ferreira, E., Porter, R. M., Wehling, N., O'Sullivan, R. P., Liu, F., Boskey, A., Estok, D. M., Harris, M. B., Vrahas, M. S., Evans, C. H. & Wells, J. W., Oct 11 2013, In : Journal of Biological Chemistry. 288, 41, p. 29494-29505 12 p.

Research output: Contribution to journalArticle

43 Scopus citations
2012

Design, characterisation and in vivo testing of a new, adjustable stiffness, external fixator for the rat femur

Glatt, V., Evans, C. H. & Matthys, R., Jan 2012, In : European Cells and Materials. 23, p. 289-299 11 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Effect of BMP-12, TGF-β1 and autologous conditioned serum on growth factor expression in Achilles tendon healing

Heisterbach, P. E., Todorov, A., Flückiger, R., Evans, C. H. & Majewski, M., Jan 1 2012, In : Knee Surgery, Sports Traumatology, Arthroscopy. 20, 10, p. 1907-1914 8 p.

Research output: Contribution to journalArticle

38 Scopus citations

Evaluation of BMP-2 gene-activated muscle grafts for cranial defect repair

Liu, F., Porter, R. M., Wells, J., Glatt, V., Pilapil, C. & Evans, C. H., Jul 1 2012, In : Journal of Orthopaedic Research. 30, 7, p. 1095-1102 8 p.

Research output: Contribution to journalArticle

25 Scopus citations

EWS-FLI-1-targeted cytotoxic T-cell killing of multiple tumor types belonging to the Ewing sarcoma family of tumors

Evans, C. H., Liu, F., Porter, R. M., O'Sullivan, R. P., Merghoub, T., Lunsford, E. P., Robichaud, K., Van Valen, F., Lessnick, S. L., Gebhardt, M. C. & Wells, J. W., Oct 1 2012, In : Clinical Cancer Research. 18, 19, p. 5341-5351 11 p.

Research output: Contribution to journalArticle

26 Scopus citations

Gene delivery to bone

Evans, C. H., Sep 1 2012, In : Advanced Drug Delivery Reviews. 64, 12, p. 1331-1340 10 p.

Research output: Contribution to journalReview article

76 Scopus citations

Genetic mismatch affects the immunosuppressive properties of mesenchymal stem cells in vitro and their ability to influence the course of collagen-induced arthritis

Sullivan, C., Murphy, J. M., Griffin, M. D., Porter, R. M., Evans, C. H., O'Flatharta, C., Shaw, G. & Barry, F., Jul 19 2012, In : Arthritis Research and Therapy. 14, 4, R167.

Research output: Contribution to journalArticle

28 Scopus citations

Improved healing of large segmental defects in the rat femur by reverse dynamization in the presence of bone morphogenetic protein-2

Glatt, V., Miller, M., Ivkovic, A., Liu, F., Parry, N., Griffin, D., Vrahas, M. & Evans, C., Nov 21 2012, In : Journal of Bone and Joint Surgery - Series A. 94, 22, p. 2063-2073 11 p.

Research output: Contribution to journalArticle

32 Scopus citations

Improvement of tendon repair using muscle grafts transduced with TGF-β1 cDNA

Majewski, M., Porter, R. M., Betz, O. B., Betz, V. M., Clahsen, H., Flückiger, R. & Evans, C. H., Jan 2012, In : European Cells and Materials. 23, p. 94-102 9 p.

Research output: Contribution to journalArticle

Open Access
32 Scopus citations

Orthopedic gene therapy-lost in translation?

Evans, C. H., Ghivizzani, S. C. & Robbins, P. D., Jan 1 2012, In : Journal of Cellular Physiology. 227, 2, p. 416-420 5 p.

Research output: Contribution to journalArticle

28 Scopus citations
2011

Autologous bone grafting on steroids: Preliminary clinical results. A novel treatment for nonunions and segmental bone defects

Miller, M. A., Ivkovic, A., Porter, R., Harris, M. B., Estok, D. M., Smith, R. M., Evans, C. H. & Vrahas, M. S., Apr 1 2011, In : International Orthopaedics. 35, 4, p. 599-605 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

Barriers to the clinical translation of orthopedic tissue engineering

Evans, C. H., Dec 1 2011, In : Tissue Engineering - Part B: Reviews. 17, 6, p. 437-441 5 p.

Research output: Contribution to journalReview article

35 Scopus citations
57 Scopus citations

Gene therapy for the regeneration of bone

Evans, C., Jun 2011, In : Injury. 42, 6, p. 599-604 6 p.

Research output: Contribution to journalArticle

43 Scopus citations

Getting arthritis gene therapy into the clinic

Evans, C. H., Ghivizzani, S. C. & Robbins, P. D., Apr 1 2011, In : Nature Reviews Rheumatology. 7, 4, p. 244-249 6 p.

Research output: Contribution to journalReview article

46 Scopus citations

Mesenchymal stem cell characteristics of human anterior cruciate ligament outgrowth cells

Steinert, A. F., Kunz, M., Prager, P., Barthel, T., Jakob, F., Nöth, U., Murray, M. M., Evans, C. H. & Porter, R. M., May 1 2011, In : Tissue Engineering - Part A. 17, 9-10, p. 1375-1388 14 p.

Research output: Contribution to journalArticle

74 Scopus citations

Regenerative medicine and tissue engineering in orthopaedic surgery

Ivkovic, A., Marijanovic, I., Hudetz, D., Porter, R. M., Pecina, M. & Evans, C. H., Jan 6 2011, In : Frontiers in Bioscience - Elite. 3 E, 3, p. 923-944 22 p.

Research output: Contribution to journalArticle

47 Scopus citations
2010

Application of structural rigidity analysis to assess fidelity of healed fractures in rat femurs with critical defects

Nazarian, A., Pezzella, L., Tseng, A., Baldassarri, S., Zurakowski, D., Evans, C. H. & Snyder, B. D., May 1 2010, In : Calcified Tissue International. 86, 5, p. 397-403 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Arthritis gene therapy trials reach phase II

Evans, C., Apr 2010, In : Journal of Rheumatology. 37, 4, p. 683-685 3 p.

Research output: Contribution to journalEditorial

11 Scopus citations

BMP12 and BMP13 gene transfer induce ligamentogenic differentiation in mesenchymal progenitor and anterior cruciate ligament cells

Haddad-Weber, M., Prager, P., Kunz, M., Seefried, L., Jakob, F., Murray, M. M., Evans, C. H., Nöth, U. & Steinert, A. F., Jul 2010, In : Cytotherapy. 12, 4, p. 505-513 9 p.

Research output: Contribution to journalArticle

60 Scopus citations

Gene therapy for bone healing

Evans, C. H., Feb 1 2010, In : Expert Reviews in Molecular Medicine. 12, e18.

Research output: Contribution to journalReview article

57 Scopus citations

Gene therapy for osteoarthritis

Ghivizzani, S. C. & Evans, C. H., Jan 1 2010, Glutamate-based Therapies for Psychiatric Disorders. Springer Basel, p. 91-112 22 p. (Milestones in Drug Therapy).

Research output: Chapter in Book/Report/Conference proceedingChapter

Non-destructive evaluation of human mesenchymal progenitor cell transcriptional activity within osteochondral defects

Porter, R. M., Liu, F. J., Ferreira, E., Shen, Z. & Evans, C. H., Jul 2010, In : European Cells and Materials. 20, SUPPL.2, 1 p.

Research output: Contribution to journalArticle

Use of genetically modified muscle and fat grafts to repair defects in bone and cartilage

Evans, C. H., Liu, F. J., Glatt, V., Hoyland, J. A., Kirker-Head, C., Walsh, A., Betz, O., Wells, J. W., Betz, V., Porter, R. M., Saad, F. A., Gerstenfeld, L. C., Einhorn, T. A., Harris, M. B. & Vrahas, M. S., Jan 1 2010, In : European Cells and Materials. 19, p. 96-111 16 p.

Research output: Contribution to journalArticle

69 Scopus citations
2009

Ability of recombinant human bone morphogenetic protein 2 to enhance bone healing in the presence of tobramycin: Evaluation in a rat segmental defect model

Glatt, V., Kwong, F. N., Park, K., Parry, N., Griffin, D., Vrahas, M., Evans, C. H. & Harris, M., Nov 1 2009, In : Journal of orthopaedic trauma. 23, 10, p. 693-701 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

Accelerated healing of the rat Achilles tendon in response to autologous conditioned serum

Majewski, M., Ochsner, P. E., Liu, F., Flückiger, R. & Evans, C. H., Dec 2 2009, In : American Journal of Sports Medicine. 37, 11, p. 2117-2125 9 p.

Research output: Contribution to journalArticle

58 Scopus citations

Altered relative expression of BMPs and BMP inhibitors in cartilaginous areas of human fractures progressing towards nonunion

Kwong, F. N. K., Hoyland, J. A., Freemont, A. J. & Evans, C. H., Jun 1 2009, In : Journal of Orthopaedic Research. 27, 6, p. 752-757 6 p.

Research output: Contribution to journalArticle

42 Scopus citations

Clinical responses to gene therapy in joints of two subjects with rheumatoid arthritis

Wehling, P., Reinecke, J., Baltzer, A. W. A., Granrath, M., Schulitz, K. P., Schultz, C., Krauspe, R., Whiteside, T. W., Elder, E., Ghivizzani, S. C., Robbins, P. D. & Evans, C. H., Feb 1 2009, In : Human gene therapy. 20, 2, p. 97-101 5 p.

Research output: Contribution to journalArticle

54 Scopus citations

Enhanced in vitro chondrogenesis of primary mesenchymal stem cells by combined gene transfer

Steinert, A. F., Palmer, G. D., Pilapil, C., Nöth, U., Evans, C. H. & Ghivizzani, S. C., May 1 2009, In : Tissue Engineering - Part A. 15, 5, p. 1127-1139 13 p.

Research output: Contribution to journalArticle

81 Scopus citations

Gene therapy of the rheumatic diseases: 1998 to 2008

Evans, C. H., Ghivizzani, S. C. & Robbins, P. D., Jan 30 2009, In : Arthritis Research and Therapy. 11, 1, 209.

Research output: Contribution to journalReview article

31 Scopus citations

Hypertrophy is induced during the in vitro chondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein-2 and bone morphogenetic protein-4 gene transfer

Steinert, A. F., Proffen, B., Kunz, M., Hendrich, C., Ghivizzani, S. C., Nöth, U., Rethwilm, A., Eulert, J. & Evans, C. H., Oct 2 2009, In : Arthritis Research and Therapy. 11, 5, R148.

Research output: Contribution to journalArticle

103 Scopus citations

In situ modification of progenitor cells for the expedited regeneration of skeletal tissues

Evans, C. H., Aug 1 2009, In : European Cells and Materials. 18, SUPPL. 1, 1 p.

Research output: Contribution to journalArticle

Interleukin-1β and tumor necrosis factor α inhibit chondrogenesis by human mesenchymal stem cells through NF-κB-dependent pathways

Wehling, N., Palmer, G. D., Pilapil, C., Liu, F., Wells, J. W., Müller, P. E., Evans, C. H. & Porter, R. M., Mar 1 2009, In : Arthritis and rheumatism. 60, 3, p. 801-812 12 p.

Research output: Contribution to journalArticle

151 Scopus citations

Intra-articular gene delivery and expression of interleukin-1Ra mediated by self-complementary adeno-associated virus

Kay, J. D., Gouze, E., Oligino, T. J., Gouze, J. N., Watson, R. S., Levings, P. P., Bush, M. L., Dacanay, A., Nickerson, D. M., Robbins, P. D., Evans, C. H. & Ghivizzani, S. C., Oct 2 2009, In : Journal of Gene Medicine. 11, 7, p. 605-614 10 p.

Research output: Contribution to journalArticle

44 Scopus citations

Orthopedic gene therapy in 2008

Evans, C. H., Ghivizzani, S. C. & Robbins, P. D., Jan 1 2009, In : Molecular Therapy. 17, 2, p. 231-244 14 p.

Research output: Contribution to journalReview article

61 Scopus citations

Osteogenic potential of reamer irrigator aspirator (RIA) aspirate collected from patients undergoing hip arthroplasty

Porter, R. M., Liu, F., Pilapil, C., Betz, O. B., Vrahas, M. S., Harris, M. B. & Evans, C. H., Jan 1 2009, In : Journal of Orthopaedic Research. 27, 1, p. 42-49 8 p.

Research output: Contribution to journalArticle

88 Scopus citations

Progress and Prospects: Genetic treatments for disorders of bones and joints

Evans, C. H., Ghivizzani, S. C. & Robbins, P. D., Aug 31 2009, In : Gene Therapy. 16, 8, p. 944-952 9 p.

Research output: Contribution to journalReview article

34 Scopus citations

Regional and cellular localisation of BMPs and their inhibitors' expression in human fractures

Kwong, F. N. K., Hoyland, J. A., Evans, C. H. & Freemont, A. J., Feb 1 2009, In : International Orthopaedics. 33, 1, p. 281-288 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

Synovial fibroblasts spread rheumatoid arthritis to unaffected joints

Lefèvre, S., Knedla, A., Tennie, C., Kampmann, A., Wunrau, C., Dinser, R., Korb, A., Schnäker, E. M., Tarner, I. H., Robbins, P. D., Evans, C. H., Stürz, H., Steinmeyer, J., Gay, S., Schölmerich, J., Pap, T., Müller-Ladner, U. & Neumann, E., Dec 1 2009, In : Nature Medicine. 15, 12, p. 1414-1420 7 p.

Research output: Contribution to journalArticle

345 Scopus citations
2008

Arthritis gene therapy at an inflection point

Evans, C. H., Jun 1 2008, In : Future Rheumatology. 3, 3, p. 207-210 4 p.

Research output: Contribution to journalEditorial

8 Scopus citations

Arthritis gene therapy's first death

Evans, C. H., Ghivizzani, S. C. & Robbins, P. D., Feb 27 2008, In : Arthritis Research and Therapy. 10, 3, 110.

Research output: Contribution to journalArticle

72 Scopus citations

A simple, lanthanide-based method to enhance the transduction efficiency of adenovirus vectors

Palmer, G. D., Stoddart, M. J., Gouze, E., Gouze, J. N., Ghivizzani, S. C., Porter, R. M. & Evans, C. H., Mar 1 2008, In : Gene Therapy. 15, 5, p. 357-363 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

Bone tissue engineering and repair by gene therapy

Betz, V. M., Betz, O. B., Harris, M. B., Vrahas, M. S. & Evans, C. H., May 6 2008, In : Frontiers in Bioscience. 13, 3, p. 833-841 9 p.

Research output: Contribution to journalReview article

57 Scopus citations