• 20671 Citations
  • 82 Scopus h-Index
1976 …2019

Research output per year

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Research Output

2019

Adenoviral gene transfer of a single-chain IL-23 induces psoriatic arthritis-like symptoms in NOD mice

Flores, R. R., Carbo, L., Kim, E., Van Meter, M., De Padilla, C. M. L., Zhao, J., Colangelo, D., Yousefzadeh, M. J., Angelini, L. A., Zhang, L., Pola, E., Vo, N., Evans, C. H., Gambotto, A., Niedernhofer, L. J. & Robbins, P. D., Aug 1 2019, In : FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33, 8, p. 9505-9515 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

An Improved, Chemically Modified RNA Encoding BMP-2 Enhances Osteogenesis in Vitro and in Vivo

Zhang, W., De La Vega, R. E., Coenen, M. J., Müller, S. A., Peniche Silva, C. J., Aneja, M. K., Plank, C., Van Griensven, M., Evans, C. H. & Balmayor, E. R., Jan 1 2019, In : Tissue Engineering - Part A. 25, 1-2, p. 131-144 14 p.

Research output: Contribution to journalArticle

5 Scopus citations

Healing with RNA

Evans, C. H., De la Vega, R. E., Evans, C. H., van Griensven, M. & Balmayor, E. R., Mar 1 2019, In : Injury. 50, 3, p. 625-626 2 p.

Research output: Contribution to journalEditorial

Paracrine effects of living human bone particles on the osteogenic differentiation of mesenchymal stem cells

Atasoy-Zeybek, A., Ivkovic, A., Beyzadeoglu, T., Onal, A., Evans, C. H. & Kose, G. T., Dec 2019, In : European Cells and Materials. 38, p. 14-22 9 p.

Research output: Contribution to journalArticle

Open Access

Regenerative rehabilitation: The role of mechanotransduction in orthopaedic regenerative medicine

Glatt, V., Evans, C. H. & Stoddart, M. J., Jun 2019, In : Journal of Orthopaedic Research. 37, 6, p. 1263-1269 7 p.

Research output: Contribution to journalReview article

2 Scopus citations

Response of the Injured Tendon to Growth Factors in the Presence or Absence of the Paratenon

Müller, S. A., Quirk, N. P., Müller-Lebschi, J. A., Heisterbach, P. E., Dürselen, L., Majewski, M. & Evans, C. H., Feb 1 2019, In : American Journal of Sports Medicine. 47, 2, p. 462-467 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

RNA Therapeutics for Tissue Engineering

Balmayor, E. R. & Evans, C. H., Jan 1 2019, In : Tissue Engineering - Part A. 25, 1-2, p. 9-11 3 p.

Research output: Contribution to journalReview article

2 Scopus citations

Specific, sensitive, and stable reporting of human mesenchymal stromal cell chondrogenesis

De La Vega, R. E., Scheu, M., Brown, L. A., Evans, C. H., Ferreira, E. & Porter, R. M., Mar 1 2019, In : Tissue Engineering - Part C: Methods. 25, 3, p. 176-190 15 p.

Research output: Contribution to journalArticle

1 Scopus citations

The vicissitudes of gene therapy

Evans, C. H., Jan 1 2019, In : Bone and Joint Research. 8, 10, p. 469-471 3 p.

Research output: Contribution to journalReview article

Open Access
2018

Arthritis Gene Therapy Approved in Korea

Evans, C. H., Ghivizzani, S. C. & Robbins, P. D., Jan 15 2018, In : Journal of the American Academy of Orthopaedic Surgeons. 26, 2, p. e36-e38

Research output: Contribution to journalArticle

6 Scopus citations

Arthritis gene therapy is becoming a reality

Evans, C. H., Ghivizzani, S. C. & Robbins, P. D., May 9 2018, (Accepted/In press) In : Nature Reviews Rheumatology. p. 1-2 2 p.

Research output: Contribution to journalArticle

7 Scopus citations

Catering to chondrocytes

Evans, C. H., Nov 28 2018, In : Science Translational Medicine. 10, 469, eaav7043.

Research output: Contribution to journalArticle

2 Scopus citations

Editorial: Arthritis Gene Therapy Using Interleukin-1 Receptor Antagonist

Evans, C., Nov 2018, In : Arthritis and Rheumatology. 70, 11, p. 1699-1701 3 p.

Research output: Contribution to journalEditorial

Effects of freeze-thaw on the biomechanical and structural properties of the rat Achilles tendon

Quirk, N. P., Lopez De Padilla, C., De La Vega, R. E., Coenen, M. J., Tovar, A., Evans, C. H. & Müller, S. A., Nov 16 2018, In : Journal of Biomechanics. 81, p. 52-57 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Gene Delivery to Joints by Intra-Articular Injection

Evans, C. H., Ghivizzani, S. C. & Robbins, P. D., Jan 1 2018, In : Human Gene Therapy. 29, 1, p. 2-14 13 p.

Research output: Contribution to journalReview article

22 Scopus citations

Gene therapy for osteoarthritis: Pharmacokinetics of intra-articular self-complementary adeno-associated virus interleukin-1 receptor antagonist delivery in an equine model

Watson Levings, R. S., Broome, T. A., Smith, A. D., Rice, B. L., Gibbs, E. P., Myara, D. A., Hyddmark, E. V., Nasri, E., Zarezadeh, A., Levings, P. P., Lu, Y., White, M. E., Dacanay, E. A., Foremny, G. B., Evans, C. H., Morton, A. J., Winter, M., Dark, M. J., Nickerson, D. M., Colahan, P. T. & 1 others, Ghivizzani, S. C., Jun 1 2018, In : Human Gene Therapy Clinical Development. 29, 2, p. 90-100 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

Gene therapy to enhance bone and cartilage repair in orthopaedic surgery

Bougioukli, S., Evans, C. H., Alluri, R. K., Ghivizzani, S. C. & Lieberman, J. R., Jan 1 2018, In : Current Gene Therapy. 18, 3, p. 154-170 17 p.

Research output: Contribution to journalReview article

6 Scopus citations

Image Analysis Software as a Strategy to Improve the Radiographic Determination of Fracture Healing

Duryea, J., Evans, C. & Glatt, V., Sep 1 2018, In : Journal of orthopaedic trauma. 32, 9, p. e354-e358

Research output: Contribution to journalArticle

Improved tendon healing using bFGF, BMP-12 and TGFβ1 in a rat model

Majewski, M., Heisterbach, P., Jaquiéry, C., Dürselen, L., Todorov, A., Martin, I., Evans, C. H. & Müller, S. A., Jan 1 2018, In : European Cells and Materials. 35, p. 318-334 17 p.

Research output: Contribution to journalArticle

3 Scopus citations

Self-complementary adeno-associated virus-mediated interleukin-1 receptor antagonist gene delivery for the treatment of osteoarthritis: Test of efficacy in an equine model

Watson Levings, R. S., Smith, A. D., Broome, T. A., Rice, B. L., Gibbs, E. P., Myara, D. A., Hyddmark, E. V., Nasri, E., Zarezadeh, A., Levings, P. P., Lu, Y., White, M. E., Dacanay, E. A., Foremny, G. B., Evans, C. H., Morton, A. J., Winter, M., Dark, M. J., Nickerson, D. M., Colahan, P. T. & 1 others, Ghivizzani, S. C., Jun 1 2018, In : Human Gene Therapy Clinical Development. 29, 2, p. 101-112 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

State of art and limitations in genetic engineering to induce stable chondrogenic phenotype

Graceffa, V., Vinatier, C., Guicheux, J., Evans, C. H., Stoddart, M., Alini, M. & Zeugolis, D. I., Jan 1 2018, (Accepted/In press) In : Biotechnology Advances.

Research output: Contribution to journalArticle

4 Scopus citations

The Role of the Paratenon in Achilles Tendon Healing: A Study in Rats

Müller, S. A., Evans, C. H., Heisterbach, P. E. & Majewski, M., Apr 1 2018, In : American Journal of Sports Medicine. 46, 5, p. 1214-1219 6 p.

Research output: Contribution to journalArticle

10 Scopus citations
2017

A concert between biology and biomechanics: The influence of the mechanical environment on bone healing

Glatt, V., Evans, C. H. & Tetsworth, K., 2017, In : Frontiers in Physiology. 7, JAN, 678.

Research output: Contribution to journalReview article

20 Scopus citations

Contribution of Implanted, Genetically Modified Muscle Progenitor Cells Expressing BMP-2 to New Bone Formation in a Rat Osseous Defect

De La Vega, R. E., De Padilla, C. L., Trujillo, M., Quirk, N., Porter, R. M., Evans, C. H. & Ferreira, E., 2017, (Accepted/In press) In : Molecular Therapy.

Research output: Contribution to journalArticle

5 Scopus citations

Effectiveness of intra-articular therapies in osteoarthritis: a literature review

Wehling, P., Evans, C. H., Wehling, J. & Maixner, W., Aug 1 2017, In : Therapeutic Advances in Musculoskeletal Disease. 9, 8, p. 183-196 14 p.

Research output: Contribution to journalReview article

40 Scopus citations

Extended release of proteins following encapsulation in hydroxyapatite/chitosan composite scaffolds for bone tissue engineering applications

Devine, D. M., Hoctor, E., Hayes, J. S., Sheehan, E. & Evans, C. H., Jan 1 2017, (Accepted/In press) In : Materials Science and Engineering C.

Research output: Contribution to journalArticle

4 Scopus citations

Intra-articular dexamethasone to inhibit the development of post-traumatic osteoarthritis

Grodzinsky, A. J., Wang, Y., Kakar, S., Vrahas, M. S. & Evans, C. H., Mar 1 2017, In : Journal of Orthopaedic Research. 35, 3, p. 406-411 6 p.

Research output: Contribution to journalReview article

24 Scopus citations
2016

Autologous Conditioned Serum

Evans, C. H., Chevalier, X. & Wehling, P., Nov 1 2016, In : Physical Medicine and Rehabilitation Clinics of North America. 27, 4, p. 893-908 16 p.

Research output: Contribution to journalReview article

10 Scopus citations

Drug delivery to chondrocytes

Evans, C. H., Jan 1 2016, In : Osteoarthritis and Cartilage. 24, 1, p. 1-3 3 p.

Research output: Contribution to journalArticle

9 Scopus citations

Effect of a Simple Collagen Type i Sponge for Achilles Tendon Repair in a Rat Model

Müller, S. A., Dürselen, L., Heisterbach, P., Evans, C. H. & Majewski, M., Aug 1 2016, In : American Journal of Sports Medicine. 44, 8, p. 1998-2004 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Improving translation success of cell-based therapies in orthopaedics

Bara, J. J., Herrmann, M., Evans, C. H., Miclau, T., Ratcliffe, A. & Richards, R. G., Jan 1 2016, In : Journal of Orthopaedic Research. 34, 1, p. 17-21 5 p.

Research output: Contribution to journalArticle

8 Scopus citations

Interaction between living bone particles and rhBMP-2 in large segmental defect healing in the rat femur

Liu, F., Wells, J. W., Porter, R. M., Glatt, V., Shen, Z., Schinhan, M., Ivkovic, A., Vrahas, M. S., Evans, C. H. & Ferreira, E., 2016, (Accepted/In press) In : Journal of Orthopaedic Research.

Research output: Contribution to journalArticle

7 Scopus citations

Reverse dynamization: A novel approach to bone healing

Glatt, V., Tepic, S. & Evans, C. H., Jul 1 2016, In : Journal of the American Academy of Orthopaedic Surgeons. 24, 7, p. e60-e61

Research output: Contribution to journalShort survey

2 Scopus citations

Reverse dynamization influence of fixator stiffness on the mode and efficiency of large-bone-defect healing at different doses of rhBMP-2

Glatt, V., Bartnikowski, N., Quirk, N., Schuetz, M. & Evans, C. H., Apr 20 2016, In : Journal of Bone and Joint Surgery - American Volume. 98, 8, p. 677-687 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

Safety and biodistribution assessment of sc-rAAV2.5IL-1Ra administered via intra-articular injection in a mono-iodoacetate-induced osteoarthritis rat model

Wang, G., Evans, C. H., Benson, J. M., Hutt, J. A., Seagrave, J. C., Wilder, J. A., Grieger, J. C., Samulski, R. J. & Terse, P. S., Mar 16 2016, In : Molecular Therapy - Methods and Clinical Development. 3, 1 p.

Research output: Contribution to journalArticle

13 Scopus citations

Tissue engineering and regenerative approaches to improving the healing of large bone defects

Verrier, S., Alini, M., Alsberg, E., Buchman, S. R., Kelly, D., Laschke, M. W., Menger, M. D., Murphy, W. L., Stegemann, J. P., Schütz, M., Miclau, T., Stoddart, M. J. & Evans, C. H., Jul 1 2016, In : European Cells and Materials. 32, p. 87-110 24 p.

Research output: Contribution to journalArticle

36 Scopus citations

Why does bone have TERM limits?

Evans, C. H. & Stoddart, M. J., Jun 1 2016, In : Injury. 47, 6, p. 1159-1161 3 p.

Research output: Contribution to journalArticle

1 Scopus citations
2015

Biologics for tendon repair

Docheva, D., Müller, S. A., Majewski, M. & Evans, C. H., Apr 1 2015, In : Advanced Drug Delivery Reviews. 84, p. 222-239 18 p.

Research output: Contribution to journalArticle

196 Scopus citations

Gene therapy approaches to regenerating the musculoskeletal system

Evans, C. H. & Huard, J., Apr 1 2015, In : Nature Reviews Rheumatology. 11, 4, p. 234-242 9 p.

Research output: Contribution to journalArticle

107 Scopus citations

Native, Living Tissues as Cell Seeded Scaffolds

Evans, C. H., Mar 1 2015, In : Annals of Biomedical Engineering. 43, 3, p. 787-795 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Rapid and reliable healing of critical size bone defects with genetically modified sheep muscle

Liu, F., Ferreira, E., Porter, R. M., Glatt, V., Schinhan, M., Shen, Z., Randolph, M. A., Kirker-Head, C. A., Wehling, C., Vrahas, M. S., Evans, C. H. & Wells, J. W., Jan 1 2015, In : European Cells and Materials. 30, p. 118-131 14 p.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations
2014

Arthritis Gene Therapy: A Brief History and Perspective

Evans, C. H., Ghivizzani, S. C. & Robbins, P. D., Nov 17 2014, Translating Gene Therapy to the Clinic: Techniques and Approaches. Elsevier Inc., p. 85-98 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations

Barriers and strategies for the clinical translation of advanced orthopaedic tissue engineering protocols

Madry, H., Alini, M., Stoddart, M. J., Evans, C., Miclau, T. & Steiner, S., May 6 2014, In : European Cells and Materials. 27, SUPPL, p. 17-21 5 p.

Research output: Contribution to journalArticle

Open Access
21 Scopus citations

On the shoulders of giants: The future of the Journal of Orthopaedic Research

Alman, B. & Evans, C. H., 2014, In : Journal of Orthopaedic Research. 32, 9, p. 1095-1096 2 p.

Research output: Contribution to journalArticle

Preclinical toxicity evaluation of AAV for pain: Evidence from human AAV studies and from the pharmacology of analgesic drugs

Pleticha, J., Heilmann, L. F., Evans, C. H., Asokan, A., Samulski, R. J. & Beutler, A. S., Sep 2 2014, In : Molecular Pain. 10, 1, 54.

Research output: Contribution to journalReview article

12 Scopus citations

Progress in intra-articular therapy

Evans, C. H., Kraus, V. B. & Setton, L. A., Jan 1 2014, In : Nature Reviews Rheumatology. 10, 1, p. 11-22 12 p.

Research output: Contribution to journalReview article

151 Scopus citations

TNFα and IL-1β influence the differentiation and migration of murine MSCs independently of the NF-κB pathway

Sullivan, C. B., Porter, R. M., Evans, C. H., Ritter, T., Shaw, G., Barry, F. & Murphy, J. M., Aug 27 2014, In : Stem Cell Research and Therapy. 5, 4, 104.

Research output: Contribution to journalArticle

28 Scopus citations

Using genes to facilitate the endogenous repair and regeneration of orthopaedic tissues

Evans, C., Sep 2014, In : International Orthopaedics. 38, 9, p. 1761-1769 9 p.

Research output: Contribution to journalReview article

19 Scopus citations
2013

Advances in regenerative orthopedics

Evans, C. H., Nov 2013, In : Mayo Clinic proceedings. 88, 11, p. 1323-1339 17 p.

Research output: Contribution to journalArticle

43 Scopus citations

An overview of underlying causes and animal models for the study of age-related degenerative disorders of the spine and synovial joints

Vo, N., Niedernhofer, L. J., Nasto, L. A., Jacobs, L., Robbins, P. D., Kang, J. & Evans, C. H., Jun 1 2013, In : Journal of Orthopaedic Research. 31, 6, p. 831-837 7 p.

Research output: Contribution to journalReview article

53 Scopus citations