• 11954 Citations
  • 62 Scopus h-Index
1969 …2019
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Research Output 1969 2019

  • 11954 Citations
  • 62 Scopus h-Index
  • 209 Article
  • 2 Review article
  • 1 Conference contribution
  • 1 Short survey
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Article
2001
150 Citations (Scopus)

Pregnancy-associated Plasma Protein-A2 (PAPP-A2), a Novel Insulin-like Growth Factor-binding Protein-5 Proteinase

Overgaard, M. T., Bold, H. B., Laursen, L. S., Sottrup-Jensen, L., Conover, C. A. & Oxvig, C., Jun 15 2001, In : Journal of Biological Chemistry. 276, 24, p. 21849-21853 5 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor Binding Protein 5
Pregnancy-Associated Plasma Protein-A
varespladib methyl
Blood Proteins
Peptide Hydrolases
489 Citations (Scopus)

Pregnancy-associated plasma protein A as a marker of acute coronary syndromes

Bayes-Genis, A., Conover, C. A., Overgaard, M. T., Bailey, K. R., Christiansen, M., Holmes, D., Virmani, R., Oxvig, C. & Schwartz, R. S., Oct 4 2001, In : New England Journal of Medicine. 345, 14, p. 1022-1029 8 p.

Research output: Contribution to journalArticle

Pregnancy-Associated Plasma Protein-A
Acute Coronary Syndrome
Unstable Angina
Myocardial Infarction
Stable Angina
99 Citations (Scopus)

Pregnancy-associated plasma protein-A is the insulin-like growth factor binding protein-4 protease secreted by human ovarian granulosa cells and is a marker of dominant follicle selection and the corpus luteum

Conover, C. A., Faessen, G. F., Ilg, K. E., Chandrasekher, Y. A., Christiansen, M., Overgaard, M. T., Oxvig, C. & Giudice, L. C., 2001, In : Endocrinology. 142, 5, p. 2155-2158 4 p.

Research output: Contribution to journalArticle

Pregnancy-Associated Plasma Protein-A
Granulosa Cells
Corpus Luteum
Insulin-Like Growth Factor Binding Protein 4
Follicular Fluid
2000
8 Citations (Scopus)

Characterization of the enzymatic specificity of the IGF-dependent insulin-like growth factor binding protein-4 (IGFBP-4) protease

Chelius, D., Conover, C. A., Baldwin, M. A. & Spencer, E. M., 2000, In : Growth Hormone and IGF Research. 10, 6, p. 360-366 7 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor Binding Protein 4
Pregnancy-Associated Plasma Protein-A
Somatomedins
Insulin-Like Growth Factor Binding Proteins
Kallikreins
150 Citations (Scopus)

Expression of recombinant human pregnancy-associated plasma protein-A and identification of the proform of eosinophil major basic protein as its physiological inhibitor

Overgaard, M. T., Haaning, J., Boldt, H. B., Olsen, I. M., Laursen, L. S., Christiansen, M., Gleich, G. J., Sottrup-Jensen, L., Conover, C. A. & Oxvig, C., Oct 6 2000, In : Journal of Biological Chemistry. 275, 40, p. 31128-31133 6 p.

Research output: Contribution to journalArticle

Eosinophil Major Basic Protein
Pregnancy-Associated Plasma Protein-A
Insulin-Like Growth Factor Binding Protein 4
Somatomedins
Pregnancy
73 Citations (Scopus)
Phosphatidylinositol 3-Kinase
Proto-Oncogene Proteins c-akt
Insulin-Like Growth Factor Binding Protein 3
Somatomedins
IGF Type 1 Receptor
43 Citations (Scopus)

In vitro studies of insulin-like growth factor I and bone

Conover, C. A., 2000, In : Growth Hormone and IGF Research. 10, SUPPL. B

Research output: Contribution to journalArticle

Insulin-Like Growth Factor I
Insulin-Like Growth Factor Binding Proteins
Bone and Bones
Bone Matrix
Peptide Hydrolases
47 Citations (Scopus)

Mechanisms of lysolipid phosphate effects on cellular survival and proliferation

Goetzl, E. J., Lee, H., Dolezalova, H., Kalli, K. R., Conover, C. A., Hu, Y. L., Azuma, T., Stossel, T. P., Karliner, J. S. & Jaffe, R. B., 2000, In : Annals of the New York Academy of Sciences. 905, p. 177-187 11 p.

Research output: Contribution to journalArticle

G-Protein-Coupled Receptors
Phosphates
Cell Proliferation
Gene encoding
Physiology
362 Citations (Scopus)

The insulin-like growth factor axis: A review of atherosclerosis and restenosis

Bayes-Genis, A., Conover, C. A. & Schwartz, R. S., 2000, In : Circulation Research. 86, 2, p. 125-130 6 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor Binding Proteins
Somatomedins
Atherosclerosis
Insulin-Like Growth Factor I
Insulin-Like Growth Factor II
1999
12 Citations (Scopus)

A quantitative PCR measurement of messenger RNA expression of IGF-I, IGF-II and IGFBP-5 in human skeletal muscle

Schimke, J. M. C., Ljungqvist, O. H., Sarkar, G., Conover, C. A. & Nair, K. S., Jun 1999, In : Growth Hormone and IGF Research. 9, 3, p. 179-186 8 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor II
Insulin-Like Growth Factor I
Carrier Proteins
Skeletal Muscle
Polymerase Chain Reaction
61 Citations (Scopus)

A randomized trial of tamoxifen alone or combined with octreotide in the treatment of women with metastatic breast carcinoma

Ingle, J. N., Suman, V. J., Kardinal, C. G., Krook, J. E., Mailliard, J. A., Veeder, M. H., Loprinzi, C. L., Dalton, R. J., Hartmann, L. C., Conover, C. A. & Pollak, M. N., Mar 15 1999, In : Cancer. 85, 6, p. 1284-1292 9 p.

Research output: Contribution to journalArticle

Octreotide
Tamoxifen
Breast Neoplasms
Insulin-Like Growth Factor I
Therapeutics
162 Citations (Scopus)

Distinctive expression and functions of the type 4 endothelial differentiation gene-encoded G protein-coupled receptor for lysophosphatidic acid in ovarian cancer

Goetzl, E. J., Dolezalova, H., Kong, Y., Hu, Y. L., Jaffe, R. B., Kalli, K. R. & Conover, C. A., Oct 15 1999, In : Cancer Research. 59, 20, p. 5370-5375 6 p.

Research output: Contribution to journalArticle

G-Protein-Coupled Receptors
Ovarian Neoplasms
Epithelial Cells
Genes
Serum Response Element
71 Citations (Scopus)

Effects of androgens on the insulin-like growth factor system in an androgen-responsive human osteoblastic cell line

Gori, F., Hofbauer, L. C., Conover, C. A. & Khosla, S., 1999, In : Endocrinology. 140, 12, p. 5579-5586 8 p.

Research output: Contribution to journalArticle

Somatomedins
Androgens
Insulin-Like Growth Factor I
Cell Line
Insulin-Like Growth Factor Binding Proteins
96 Citations (Scopus)

Evidence that the insulin-like growth factor binding protein-4 protease in human ovarian follicular fluid is pregnancy associated plasma protein-A

Conover, C. A., Oxvig, C., Overgaard, M. T., Christiansen, M. & Giudice, L. C., 1999, In : Journal of Clinical Endocrinology and Metabolism. 84, 12, p. 4742-4745 4 p.

Research output: Contribution to journalArticle

Pregnancy-Associated Plasma Protein-A
Follicular Fluid
Fluids
Insulin-Like Growth Factor Binding Protein 4
Follicular Atresia
89 Citations (Scopus)

Messenger ribonucleic acid levels of pregnancy-associated plasma protein-A and the proform of eosinophil major basic protein: Expression in human reproductive and nonreproductive tissues

Overgaard, M. T., Oxvig, C., Christiansen, M., Lawrence, J. B., Conover, C. A., Gleich, G. J., Sottrup-Jensen, L. & Haaning, J., 1999, In : Biology of Reproduction. 61, 4, p. 1083-1089 7 p.

Research output: Contribution to journalArticle

Eosinophil Major Basic Protein
Pregnancy-Associated Plasma Protein-A
RNA
Messenger RNA
Placenta
74 Citations (Scopus)

Response of bipotential human marrow stromal cells to insulin-like growth factors: Effect on binding protein production, proliferation, and commitment to osteoblasts and adipocytes

Thomas, T., Gori, F., Spelsberg, T. C., Khosla, S., Riggs, B. L. & Conover, C. A., 1999, In : Endocrinology. 140, 11, p. 5036-5044 9 p.

Research output: Contribution to journalArticle

Somatomedins
Stromal Cells
Osteoblasts
Adipocytes
Carrier Proteins
548 Citations (Scopus)

The insulin-like growth factor (IGF)-dependent IGF binding protein-4 protease secreted by human fibroblasts is pregnancy-associated plasma protein-A

Lawrence, J. B., Oxvig, C., Overgaard, M. T., Sottrup-Jensen, L., Gleich, G. J., Hays, L. G., Yates, J. R. & Conover, C. A., Mar 16 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 6, p. 3149-3153 5 p.

Research output: Contribution to journalArticle

Pregnancy-Associated Plasma Protein-A
Somatomedins
Fibroblasts
Insulin-Like Growth Factor Binding Protein 4
Insulin-Like Growth Factor Binding Proteins
1998
82 Citations (Scopus)

Biological characterization of human epithelial ovarian carcinoma cells in primary culture: The insulin-like growth factor system

Conover, C. A., Hartmann, L. C., Bradley, S., Stalboerger, P., Klee, G. G., Kalli, K. R. & Jenkins, R. B., Feb 1 1998, In : Experimental Cell Research. 238, 2, p. 439-449 11 p.

Research output: Contribution to journalArticle

Primary Cell Culture
Somatomedins
Carcinoma
Ovarian Neoplasms
Growth
63 Citations (Scopus)

Estrogen effects on insulin-like growth factor gene expression in a human osteoblastic cell line with high levels of estrogen receptor

Kassem, M., Okazaki, R., Harris, S. A., Spelsberg, T. C., Conover, C. A. & Riggs, B. L., 1998, In : Calcified Tissue International. 62, 1, p. 60-66 7 p.

Research output: Contribution to journalArticle

Somatomedins
Insulin-Like Growth Factor I
Estrogen Receptors
Estrogens
Gene Expression
33 Citations (Scopus)

Frequent homozygous deletions in the FRA3B region in tumor cell lines still leave the FHIT exons intact

Wang, L., Darling, J., Zhang, J. S., Qian, C. P., Hartmann, L., Conover, C. A., Jenkins, R. B. & Smith, D. I., Feb 5 1998, In : Oncogene. 16, 5, p. 635-642 8 p.

Research output: Contribution to journalArticle

Tumor Cell Line
Exons
Cell Line
Virus Integration
Trinucleotide Repeats
10 Citations (Scopus)
Insulin Receptor
Insulin-Like Growth Factor I
Fibroblasts
Insulin
IGF Type 1 Receptor
81 Citations (Scopus)

Insulin-like growth factor system abnormalities in hepatitis C- associated osteosclerosis. Potential insights into increasing bone mass in adults

Khosla, S., Hassoun, A. A. K., Baker, B. K., Liu, F., Zein, N. N., Whyte, M. P., Reasner, C. A., Nippoldt, T. B., Tiegs, R. D., Hintz, R. L. & Conover, C. A., May 15 1998, In : Journal of Clinical Investigation. 101, 10, p. 2165-2173 9 p.

Research output: Contribution to journalArticle

Osteosclerosis
Insulin-Like Growth Factor II
Somatomedins
Hepatitis C
Insulin-Like Growth Factor Binding Protein 2
Insulin-Like Growth Factor Binding Proteins
insulin-like growth factor binding proteins
Serine Proteases
serine proteinases
Peptide Hydrolases
13 Citations (Scopus)

Recommendations for nomenclature of the insulin-like growth factor binding protein (IGFBP) superfamily

Baxter, R. C., Binoux, M., Clemmons, D. R., Conover, C. A., Holly, J. M. P., Mohan, S., Oh, Y. & Rosenfeld, R. G., 1998, In : Growth Hormone and IGF Research. 8, 3, p. 273-274 2 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor Binding Proteins
Terminology
40 Citations (Scopus)

Recommendations for nomenclature of the insulin-like growth factor binding protein superfamily

Baxter, R. C., Binoux, M. A., Clemmons, D. R., Conover, C. A., Drop, S. L. S., Holly, J. M. P., Mohan, S., Oh, Y. & Rosenfeld, R. G., 1998, In : Journal of Clinical Endocrinology and Metabolism. 83, 9, p. 3213 1 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor Binding Proteins
Terminology
64 Citations (Scopus)

Recommendations for nomenclature of the insulin-like growth factor binding protein superfamily

Baxter, R. C., Binoux, M. A., Clemmons, D. R., Conover, C. A., Drop, S. L. S., Holly, J. M. P., Mohan, S., Oh, Y. & Rosenfeld, R. G., 1998, In : Endocrinology. 139, 10, p. 4036 1 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor Binding Proteins
Terminology
1997
27 Citations (Scopus)

Bioactivity of a 29-kilodalton insulin-like growth factor binding protein-3 fragment present in excess in chronic renal failure serum

Durham, S. K., Mohan, S., Liu, F., Baker, B. K., Lee, P. D. K., Hintz, R. L., Conover, C. A. & Powell, D. R., Sep 1997, In : Pediatric Research. 42, 3, p. 335-341 7 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor Binding Proteins
Insulin-Like Growth Factor Binding Protein 3
Chronic Kidney Failure
Insulin-Like Growth Factor I
Serum
18 Citations (Scopus)

Evaluation of continuous infusion suramin in metastatic breast cancer: Impact on plasma levels of insulin-like growth factors (IGFs) and IGF- binding proteins

Lawrence, J. B., Conover, C. A., Haddad, T. C., Ingle, J. N., Reid, J. M., Ames, M. M., Suman, V. J., Marks, R. S., Erlichman, C. & Hartmann, L. C., Oct 1997, In : Clinical Cancer Research. 3, 10, p. 1713-1720 8 p.

Research output: Contribution to journalArticle

Suramin
Insulin-Like Growth Factor Binding Proteins
Somatomedins
Breast Neoplasms
Insulin-Like Growth Factor I
40 Citations (Scopus)
Insulin-Like Growth Factor I
Growth Hormone
3 Citations (Scopus)

IGFs and Cellular Aging

Conover, C. A., 1997, In : Endocrine. 7, 1, p. 93-94 2 p.

Research output: Contribution to journalArticle

IGF Type 1 Receptor
Insulin-Like Growth Factor Binding Protein 3
Cell Aging
Somatomedins
22 Citations (Scopus)
Insulin Receptor Substrate Proteins
Somatomedins
Interleukin-4
Insulin-Like Growth Factor I
Insulin
431 Citations (Scopus)

Insulin-like growth factor binding protein-1: Recent findings and new directions

Lee, P. D. K., Giudice, L. C., Conover, C. A. & Powell, D. R., Dec 1997, In : Proceedings of the Society for Experimental Biology and Medicine. 216, 3, p. 319-357 39 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor Binding Protein 1
Insulin
Direction compound
Physiology
Insulin-Like Growth Factor Binding Proteins
1996
51 Citations (Scopus)

Factors regulating insulin-like growth factor-binding protein-3 binding, processing, and potentiation of insulin-like growth factor action

Conover, C. A., Clarkson, J. T. & Bale, L. K., 1996, In : Endocrinology. 137, 6, p. 2286-2292 7 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor Binding Protein 3
Somatomedins
Protein Binding
Insulin-Like Growth Factor I
Chloroquine
54 Citations (Scopus)

Insulin-like growth factor-binding protein-1 expression in cultured human bone cells: Regulation by insulin and glucocorticoid

Conover, C. A., Lee, P. D. K., Riggs, B. L. & Powell, D. R., 1996, In : Endocrinology. 137, 8, p. 3295-3301 7 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor Binding Protein 1
Glucocorticoids
Insulin
Bone and Bones
Insulin Receptor

Mrna levels of insulin-like growth factor 1 and II and binding proteins 4 and 5 in human skeletal muscle

Coenen Schimke, J. M., Ljungqvist, O., Sarkar, G., Conover, C. A. & Nair, K. S., 1996, In : Journal of Investigative Medicine. 44, 3

Research output: Contribution to journalArticle

Insulin-Like Growth Factor II
Somatomedins
Muscle
Carrier Proteins
Skeletal Muscle
55 Citations (Scopus)

Potential mechanism of estrogen-mediated decrease in bone formation: estrogen increases production of inhibitory insulin-like growth factor-binding protein-4.

Kassem, M., Okazaki, R., De León, D., Harris, S. A., Robinson, J. A., Spelsberg, T. C., Conover, C. A. & Riggs, B. L., Mar 1996, In : Proceedings of the Association of American Physicians. 108, 2, p. 155-164 10 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor Binding Protein 4
Osteogenesis
Estrogens
Somatomedins
Insulin-Like Growth Factor Binding Protein 3
49 Citations (Scopus)

Regulation and physiological role of insulin-like growth factor binding proteins

Conover, C. A., 1996, In : Endocrine Journal. 43, SUPPL.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor Binding Proteins
Somatomedins
Insulin
Anabolic Agents
Post Translational Protein Processing
1995
28 Citations (Scopus)

Alterations in insulin-like growth factor (IGF)-dependent IGF-binding protein-4 proteolysis in transformed osteoblastic cells

Durham, S. K., Riggs, B. L., Harris, S. A. & Conover, C. A., 1995, In : Endocrinology. 136, 4, p. 1340-1347 8 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor Binding Protein 4
Somatomedins
Proteolysis
Peptide Hydrolases
Osteoblasts

Alterations in insulin-like growth factor (IGF)-dependent IGF-binding protein-4 proteolysis in transformed osteoblastic cells

Durham, S. K., Riggs, B. L., Harris, S. A. & Conover, C. A., 1995, In : Endocrinology. 136, 4, p. 1374-1380 7 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor Binding Protein 4
Somatomedins
Proteolysis
Peptide Hydrolases
Osteoblasts
87 Citations (Scopus)

Cleavage analysis of insulin-like growth factor (IGF)-dependent IGF- binding protein-4 proteolysis and expression of protease-resistant IGF- binding protein-4 mutants

Conover, C. A., Durham, S. K., Zapf, J., Masiarz, F. R. & Kiefer, M. C., 1995, In : Journal of Biological Chemistry. 270, 9, p. 4395-4400 6 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor Binding Protein 4
Pregnancy-Associated Plasma Protein-A
Proteolysis
Somatomedins
Peptide Hydrolases
9 Citations (Scopus)

Differential effects of glucocorticoids on insulin-like growth factor I action in cultured human fibroblasts

Conover, C. A., Hintz, R. L. & Johnson, B. F., Jun 1995, In : Journal of Cellular Physiology. 163, 3, p. 615-622 8 p.

Research output: Contribution to journalArticle

Fibroblasts
Insulin-Like Growth Factor I
Glucocorticoids
Dexamethasone
Aminoisobutyric Acids
63 Citations (Scopus)

Effect of glucocorticoid on insulin-like growth factor (IGF) regulation of IGF-binding protein expression in fibroblasts

Conover, C. A., Clarkson, J. T. & Bale, L. K., 1995, In : Endocrinology. 136, 4, p. 1403-1410 8 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor Binding Proteins
Somatomedins
Insulin-Like Growth Factor I
Insulin-Like Growth Factor Binding Protein 4
Glucocorticoids
79 Citations (Scopus)
Insulin-Like Growth Factor Binding Proteins
Cathepsin D
Hydrolysis
Cells
Carcinoma
48 Citations (Scopus)

Insulin-like growth factor binding protein proteolysis in bone cell models

Conover, C. A., 1995, In : Progress in Growth Factor Research. 6, 2-4, p. 301-309 9 p.

Research output: Contribution to journalArticle

Proteolysis
Insulin-Like Growth Factor Binding Proteins
Bone
Bone and Bones
Peptide Hydrolases
43 Citations (Scopus)

Normal human osteoblast-like cells consistently express genes for insulin-like growth factors I and II but transformed human osteoblast cell lines do not

Okazaki, R., Conover, C. A., Harris, S. A., Spelsberg, T. C. & Riggs, B. L., May 1995, In : Journal of Bone and Mineral Research. 10, 5, p. 788-795 8 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor II
Osteoblasts
Insulin-Like Growth Factor I
Cell Line
Messenger RNA
29 Citations (Scopus)

Regulation of insulin-like growth factor (IGF)-binding protein-4 availability in normal human osteoblast-like cells: Role of endogenous IGFs

Durham, S. K., De Leon, D. D., Okazaki, R., Riggs, B. L. & Conover, C. A., 1995, In : Journal of Clinical Endocrinology and Metabolism. 80, 1, p. 104-110 7 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor Binding Protein 4
Osteoblasts
Availability
Somatomedins
Proteolysis
32 Citations (Scopus)
Osteoblasts
Transforming Growth Factors
Colforsin
Insulin-Like Growth Factor I
Messenger RNA
1994
102 Citations (Scopus)
Proteolysis
Cathepsin D
Insulin-Like Growth Factor Binding Protein 3
Acids
Conditioned Culture Medium
134 Citations (Scopus)

Glucocorticoid regulation of insulin-like growth factor-binding protein expression in normal human osteoblast-like cells

Okazaki, R., Riggs, B. L. & Conover, C. A., Jan 1994, In : Endocrinology. 134, 1, p. 126-132 7 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor Binding Proteins
Osteoblasts
Glucocorticoids
Insulin-Like Growth Factor Binding Protein 4
Insulin-Like Growth Factor Binding Protein 1
24 Citations (Scopus)

Insulin-like growth factor-II enhancement of human fibroblast growth via a nonreceptor-mediated mechanism

Conover, C. A., Clarkson, J. T. & Bale, L. K., Jul 1994, In : Endocrinology. 135, 1, p. 76-82 7 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor II
Fibroblasts
Insulin-Like Growth Factor I
Growth
IGF Type 2 Receptor