• 789 Citations
  • 16 Scopus h-Index
20112019
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Research Output 2011 2019

2019
Open Access
National Institute on Aging (U.S.)
Eosinophilic Esophagitis
National Institutes of Health (U.S.)
Esophagus
Epidemiology

Endoscopic Surveillance of Barrett's Esophagus Using Volumetric Laser Endomicroscopy With Artificial Intelligence Image Enhancement

Trindade, A. J., McKinley, M. J., Fan, C., Leggett, C., Kahn, A. & Pleskow, D. K., Aug 1 2019, In : Gastroenterology. 157, 2, p. 303-305 3 p.

Research output: Contribution to journalArticle

Image Enhancement
Barrett Esophagus
Artificial Intelligence
Lasers
2 Citations (Scopus)
Open Access
Eosinophilic Esophagitis
Deglutition Disorders
Esophagus
Food
Incidence

Hidden in Plain Sight

Kamboj, A. K., Nehra, V. & Leggett, C., Jun 1 2019, In : Gastroenterology. 156, 8, p. 2144-2145 2 p.

Research output: Contribution to journalComment/debate

Patient-oriented education and visual-aid intervention are inadequate to identify patients with potential capsule retention: a prospective randomized study

Al-Bawardy, B., Kamboj, A. K., Desai, S., Gorospe, E., Bruining, D. H., Gostout, C. J., Hansel, S. L., Larson, M. V., Murray, J. A., Nehra, V., Leggett, C., Szarka, L., Watson, R. E. & Rajan, E., Jan 1 2019, In : Scandinavian Journal of Gastroenterology.

Research output: Contribution to journalArticle

Audiovisual Aids
Patient Education
Capsules
Prospective Studies
Wrist
2 Citations (Scopus)

The evolution of treatment and complications of esophageal food impaction

Schupack, D. A., Lenz, C. J., Geno, D. M., Tholen, C. J., Leggett, C., Katzka, D. A. & Alexander, J. A., Jan 1 2019, In : United European Gastroenterology Journal.

Research output: Contribution to journalArticle

Open Access
Food
Endoscopy
Therapeutics
Food Safety
Glucagon

Upper Gastrointestinal Bleeding: Etiologies and Management

Kamboj, A. K., Hoversten, P. & Leggett, C., Apr 1 2019, In : Mayo Clinic proceedings. 94, 4, p. 697-703 7 p.

Research output: Contribution to journalReview article

Hemorrhage
Melena
Hematemesis
Gastrointestinal Hemorrhage
Triage

Verteporfin-and sodium porfimer-mediated photodynamic therapy enhances pancreatic cancer cell death without activating stromal cells in the microenvironment

Lu, J., Roy, B., Anderson, M., Leggett, C. L., Levy, M. J., Pogue, B., Hasan, T. & Wang, K. K., Nov 1 2019, In : Journal of Biomedical Optics. 24, 11, 118001.

Research output: Contribution to journalArticle

Open Access
Dihematoporphyrin Ether
Photodynamic therapy
Cell death
death
therapy

Volumetric laser endomicroscopy features of dysplasia at the gastric cardia in Barrett's oesophagus: results from an observational cohort study

Trindade, A. J., Raphael, K. L., Inamdar, S., Stewart, M., Berkowitz, J., Vegesna, A., Mckinley, M. J., Benias, P. C., Kahn, A., Leggett, C. L., Lee, C., Sejpal, D. V. & Rishi, A., Oct 1 2019, In : BMJ Open Gastroenterology. 6, 1, e000340.

Research output: Contribution to journalArticle

Open Access
Cardia
Barrett Esophagus
Observational Studies
Stomach
Lasers
2018
1 Citation (Scopus)

A prospective multicenter study using a new multiband mucosectomy device for endoscopic resection of early neoplasia in Barrett's esophagus

Pouw, R. E., Beyna, T., Belghazi, K., Koch, A. D., Schoon, E. J., Haidry, R., Weusten, B. L., Bisschops, R., Shaheen, N. J., Wallace, M. B., Marcon, N., Heise-Ginsburg, R., Gotink, A. W., Wang, K. K. N., Leggett, C., Ortiz-Fernández-Sordo, J., Ragunath, K., DiPietro, M., Pech, O., Neuhaus, H. & 1 others, Bergman, J. J., Jan 1 2018, (Accepted/In press) In : Gastrointestinal Endoscopy.

Research output: Contribution to journalArticle

Barrett Esophagus
Multicenter Studies
Prospective Studies
Equipment and Supplies
Confidence Intervals
Esophageal Neoplasms
Equipment and Supplies
Hemorrhage
Neoplasms
Safety
6 Citations (Scopus)

Cryotherapy for persistent Barrett's esophagus after radiofrequency ablation: a systematic review and meta-analysis

Visrodia, K., Zakko, L., Singh, S., Leggett, C., Iyer, P. G. & Wang, K. K. N., Jun 1 2018, In : Gastrointestinal Endoscopy. 87, 6, p. 1396-1404.e1

Research output: Contribution to journalReview article

Cryotherapy
Barrett Esophagus
Meta-Analysis
Metaplasia
Confidence Intervals

Erratum: Learning curve and competence for volumetric laser endomicroscopy in Barrett's esophagus using cumulative sum analysis (Endoscopy (2018) 50 (471-478) DOI: 10.1055/s-0043-121569)

Trindade, A. J., Inamdar, S., Smith, M. S., Rosen, L., Han, D., Chang, K. J., Leggett, C., Lightdale, C. J., Pleskow, D. K., Sejpal, D. V., Tearney, G. J., Thomas, R. M. & Wallace, M. B., May 1 2018, In : Endoscopy. 50, 5, p. C10

Research output: Contribution to journalComment/debate

Learning Curve
Barrett Esophagus
Mental Competency
Endoscopy
Lasers
4 Citations (Scopus)

Higher Rate of Barrett’s Detection in the First Year After Successful Endoscopic Therapy: Meta-analysis

Sawas, T., Iyer, P. G., Alsawas, M., Cotton, C. C., Leggett, C., Murad, M. H., Wang, K. K. N., Shaheen, N. J. & Katzka, D. A., Jun 14 2018, (Accepted/In press) In : American Journal of Gastroenterology. p. 1-13 13 p.

Research output: Contribution to journalArticle

Metaplasia
Meta-Analysis
Barrett Esophagus
Incidence
Adenocarcinoma

Is more always better in Barrett's esophagus?

Leggett, C., Jul 1 2018, In : Gastrointestinal Endoscopy. 88, 1, p. 43-45 3 p.

Research output: Contribution to journalEditorial

Barrett Esophagus
1 Citation (Scopus)
Barrett Esophagus
Lasers
Endoscopic Mucosal Resection
Endoscopy
Neoplasms

Screening patients for Barrett esophagus: Why, who, and how

Zakko, L., Visrodia, K., Leggett, C., Lutzke, L. & Wang, K. K. N., Apr 1 2018, In : Techniques in Gastrointestinal Endoscopy. 20, 2, p. 55-61 7 p.

Research output: Contribution to journalReview article

Barrett Esophagus
Technology
Breath Tests
Abdominal Obesity
Porifera
3 Citations (Scopus)

Step-by-step use of hemostatic powder: treatment of a bleeding GI stromal tumor

Storm, A. C., Sawas, T., Higgins, T., Bruining, D. H., Leggett, C., Buttar, N. S., Wong Kee Song, L. M. & Abu Dayyeh, B. K., Jan 1 2018, (Accepted/In press) In : VideoGIE.

Research output: Contribution to journalArticle

Hemostatics
Powders
Hemorrhage
Neoplasms
4 Citations (Scopus)

Timeline and location of recurrence following successful ablation in Barrett's oesophagus: An international multicentre study

Sami, S. S., Ravindran, A., Kahn, A., Snyder, D., Santiago, J., Ortiz-Fernandez-Sordo, J., Tan, W. K., Dierkhising, R. A., Crook, J., Heckman, M. G., Johnson, M. L., Lansing, R., Ragunath, K., Di Pietro, M., Wolfsen, H., Ramirez, F. C., Fleischer, D., Wang, K. K. N., Leggett, C., Katzka, D. A. & 1 others, Iyer, P. G., Jan 1 2018, (Accepted/In press) In : Gut.

Research output: Contribution to journalArticle

Barrett Esophagus
Multicenter Studies
Metaplasia
Recurrence
Esophagus
1 Citation (Scopus)

Volumetric laser endomicroscopy interpretation and feature analysis in dysplastic Barrett's esophagus

Kamboj, A. K., Kahn, A., Wolfsen, H. C., Trindade, A. J., Ganguly, E. K., Otaki, F., Chan, D., Zakko, L., Visrodia, K., Lutzke, L., Wang, K. K. N. & Leggett, C., Jan 1 2018, (Accepted/In press) In : Journal of Gastroenterology and Hepatology (Australia).

Research output: Contribution to journalArticle

Barrett Esophagus
Lasers
Biopsy
2017

A new aim for targeted biopsies in Barrett's esophagus

Leggett, C. & Wolfsen, H. C., Sep 1 2017, In : Gastrointestinal Endoscopy. 86, 3, p. 473-475 3 p.

Research output: Contribution to journalEditorial

Esophagoscopy
Barrett Esophagus
Esophagus
Biopsy
32 Citations (Scopus)

Breath Testing for Barrett's Esophagus Using Exhaled Volatile Organic Compound Profiling With an Electronic Nose Device

Chan, D. K., Zakko, L., Visrodia, K. H., Leggett, C., Lutzke, L. S., Clemens, M. A., Allen, J. D., Anderson, M. A. & Wang, K. K. N., Jan 1 2017, In : Gastroenterology. 152, 1, p. 24-26 3 p.

Research output: Contribution to journalArticle

Electronic Nose
Volatile Organic Compounds
Barrett Esophagus
Equipment and Supplies
35 Citations (Scopus)

Identification of volumetric laser endomicroscopy features predictive for early neoplasia in Barrett's esophagus using high-quality histological correlation

Swager, A. F., Tearney, G. J., Leggett, C., van Oijen, M. G. H., Meijer, S. L., Weusten, B. L., Curvers, W. L. & Bergman, J. J. G. H. M., May 1 2017, In : Gastrointestinal Endoscopy. 85, 5, p. 918-926.e7

Research output: Contribution to journalArticle

Barrett Esophagus
Lasers
Neoplasms
Histology
ROC Curve
7 Citations (Scopus)

Learning curve and competence for volumetric laser endomicroscopy in Barrett’s esophagus using cumulative sum analysis

Trindade, A. J., Inamdar, S., Smith, M. S., Rosen, L., Han, D., Chang, K. J., Leggett, C., Lightdale, C. J., Pleskow, D. K., Sejpal, D. V., Tearney, G. J., Thomas, R. M. & Wallace, M. B., Nov 27 2017, (Accepted/In press) In : Endoscopy.

Research output: Contribution to journalArticle

Learning Curve
Barrett Esophagus
Mental Competency
Lasers
Confidence Intervals

Making Dysphagia Easier to Swallow: A Review for the Practicing Clinician

Jansson-Knodell, C. L., Codipilly, D. C. & Leggett, C., Jun 1 2017, In : Mayo Clinic Proceedings. 92, 6, p. 965-972 8 p.

Research output: Contribution to journalReview article

Deglutition
Deglutition Disorders
Physical Examination
Physicians
14 Citations (Scopus)

Optical coherence tomography in gastroenterology: A review and future outlook

Tsai, T. H., Leggett, C., Trindade, A. J., Sethi, A., Swager, A. F., Joshi, V., Bergman, J. J., Mashimo, H., Nishioka, N. S. & Namati, E., Dec 1 2017, In : Journal of Biomedical Optics. 22, 12, 121716.

Research output: Contribution to journalReview article

Gastroenterology
Optical tomography
tomography
cardiology
Cardiology
5 Citations (Scopus)

The potential role of optical biopsy in the study and diagnosis of environmental enteric dysfunction

Thompson, A. J., Hughes, M., Anastasova, S., Conklin, L. S., Thomas, T., Leggett, C., Faubion, W. A., Miller, T. J., Delaney, P., Lacombe, F., Loiseau, S., Meining, A., Richards-Kortum, R., Tearney, G. J., Kelly, P. & Yang, G. Z., Dec 1 2017, In : Nature Reviews Gastroenterology and Hepatology. 14, 12, p. 727-738 12 p.

Research output: Contribution to journalReview article

Biopsy
Growth Disorders
Celiac Disease
Graft vs Host Disease
Critical Care

Use of volumetric laser endomicroscopy to characterize a duodenal neuroendocrine tumor

Kamboj, A. K., Muppa, P., Zakko, L., Wang, K. K. N. & Leggett, C., 2017, (Accepted/In press) In : Gastrointestinal Endoscopy.

Research output: Contribution to journalArticle

Neuroendocrine Tumors
Lasers
8 Citations (Scopus)

Volumetric laser endomicroscopy in the management of Barrett's esophagus

Trindade, A. J., Leggett, C. & Chang, K. J., Jul 1 2017, In : Current Opinion in Gastroenterology. 33, 4, p. 254-260 7 p.

Research output: Contribution to journalReview article

Barrett Esophagus
Lasers
Neoplasms
Esophageal Neoplasms
Optical Coherence Tomography
2016
8 Citations (Scopus)

Computer-aided diagnosis in GI endoscopy: looking into the future

Leggett, C. & Wang, K. K. N., Nov 1 2016, In : Gastrointestinal Endoscopy. 84, 5, p. 842-844 3 p.

Research output: Contribution to journalEditorial

Computer-Assisted Diagnosis
Gastrointestinal Endoscopy
Endoscopy
19 Citations (Scopus)

Diagnosing gastrointestinal illnesses using fecal headspace volatile organic compounds

Chan, D. K., Leggett, C. & Wang, K. K. N., Jan 28 2016, In : World Journal of Gastroenterology. 22, 4, p. 1639-1649 11 p.

Research output: Contribution to journalReview article

Volatile Organic Compounds
Electronic Nose
Smell
Gases
Heterocyclic Compounds
1 Citation (Scopus)

Endoluminal stenting via the suture-assisted flange engagement technique

Tabibian, J. H., Leggett, C., Abu Dayyeh, B. K. & Buttar, N. S., Jan 1 2016, In : Gastrointestinal Endoscopy. 83, 1, p. 249-250 2 p.

Research output: Contribution to journalArticle

Esophagoscopy
Suture Techniques
Anastomotic Leak
Esophagectomy
Sutures
2 Citations (Scopus)

Optical coherence tomography: Clinical applications in gastrointestinal endoscopy

Leggett, C., Chan, D. K. & Wang, K. K. N., Jan 1 2016, Endoscopic Imaging Techniques and Tools. Springer International Publishing, p. 115-128 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Gastrointestinal Endoscopy
Optical Coherence Tomography
Mucous Membrane
Interferometry
Technology
16 Citations (Scopus)

Volumetric laser endomicroscopy in Barrett's esophagus: Interobserver agreement for interpretation of Barrett's esophagus and associated neoplasia among high-frequency users

Trindade, A. J., Inamdar, S., Smith, M. S., Chang, K. J., Leggett, C., Lightdale, C. J., Pleskow, D. K., Sejpal, D. V., Tearney, G. J., Thomas, R. M. & Wallace, M. B., Aug 2 2016, (Accepted/In press) In : Gastrointestinal Endoscopy.

Research output: Contribution to journalArticle

Barrett Esophagus
Lasers
Confidence Intervals
Neoplasms
Cardia
2015
10 Citations (Scopus)

Clinical and Histologic Determinants of Mortality for Patients With Barrett's Esophagus-Related T1 Esophageal Adenocarcinoma

Leggett, C., Lewis, J. T., Wu, T. T., Schleck, C. D., Zinsmeister, A. R., Dunagan, K. T., Lutzke, L. S., Wang, K. K. N. & Iyer, P. G., Apr 1 2015, In : Clinical Gastroenterology and Hepatology. 13, 4, p. 658-664 7 p.

Research output: Contribution to journalArticle

Barrett Esophagus
Adenocarcinoma
Mortality
Confidence Intervals
Survival
60 Citations (Scopus)

Comparative diagnostic performance of volumetric laser endomicroscopy and confocal laser endomicroscopy in the detection of dysplasia associated with Barrett's esophagus

Leggett, C., Gorospe, E. C., Chan, D. K., Muppa, P., Owens, V., Smyrk, T. C., Anderson, M., Lutzke, L. S., Tearney, G. & Wang, K. K. N., Mar 31 2015, (Accepted/In press) In : Gastrointestinal Endoscopy.

Research output: Contribution to journalArticle

Barrett Esophagus
Lasers
Confidence Intervals
Sensitivity and Specificity
Optical Coherence Tomography
44 Citations (Scopus)

Diagnosis of esophageal motility disorders: Esophageal pressure topography vs. conventional line tracing

Carlson, D. A., Ravi, K., Kahrilas, P. J., Gyawali, C. P., Bredenoord, A. J., Castell, D. O., Spechler, S. J., Halland, M., Kanuri, N., Katzka, D. A., Leggett, C., Roman, S., Saenz, J. B., Sayuk, G. S., Wong, A. C., Yadlapati, R., Ciolino, J. D., Fox, M. R. & Pandolfino, J. E., Jul 8 2015, In : American Journal of Gastroenterology. 110, 7, p. 967-977 11 p.

Research output: Contribution to journalArticle

Esophageal Motility Disorders
Pressure
Manometry
Esophageal Diseases
Gastroenterology
2 Citations (Scopus)

Mucosal imaging advanced technologies in the gastrointestinal tract

Leggett, C. & Iyer, P. G., Oct 1 2015, In : Techniques in Gastrointestinal Endoscopy. 17, 4, p. 161-170 10 p.

Research output: Contribution to journalArticle

Narrow Band Imaging
Gastrointestinal Tract
Lasers
Technology
Endoscopy
35 Citations (Scopus)

Radiofrequency Ablation Is Associated with Decreased Neoplastic Progression in Patients with Barrett's Esophagus and Confirmed Low-Grade Dysplasia

Small, A. J., Araujo, J. L., Leggett, C., Mendelson, A. H., Agarwalla, A., Abrams, J. A., Lightdale, C. J., Wang, T. C., Iyer, P. G., Wang, K. K. N., Rustgi, A. K., Ginsberg, G. G., Forde, K. A., Gimotty, P. A., Lewis, J. D., Falk, G. W. & Bewtra, M., Sep 1 2015, In : Gastroenterology. 149, 3, p. 567e3-576e3

Research output: Contribution to journalArticle

Barrett Esophagus
Adenocarcinoma
Endoscopy
Selection Bias
Retrospective Studies

RFA for early esophageal neoplasia

Chan, D. K., Leggett, C. & Wang, K. K. N., Dec 12 2015, Esophageal Cancer and Barrett's Esophagus. Wiley Blackwell, p. 151-160 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Radio
Barrett Esophagus
Neoplasms
Hot Temperature
Ablation Techniques
61 Citations (Scopus)

Safety and feasibility of volumetric laser endomicroscopy in patients with Barrett's esophagus (with videos)

Wolfsen, H. C., Sharma, P., Wallace, M. B., Leggett, C., Tearney, G. & Wang, K. K. N., Oct 1 2015, In : Gastrointestinal Endoscopy. 82, 4, p. 631-640 10 p.

Research output: Contribution to journalArticle

Barrett Esophagus
Lasers
Safety
Esophagus
Mucous Membrane
9 Citations (Scopus)

Stent-in-stent technique for removal of embedded partially covered self-expanding metal stents

DaVee, T., Irani, S., Leggett, C., Berzosa Corella, M., Grooteman, K. V., Wong Kee Song, L. M., Wallace, M. B., Kozarek, R. A. & Baron, T. H., Sep 28 2015, (Accepted/In press) In : Surgical Endoscopy and Other Interventional Techniques.

Research output: Contribution to journalArticle

Stents
Metals
2014
16 Citations (Scopus)

Application of confocal laser endomicroscopy in the diagnosis and management of Barrett's esophagus

Leggett, C. & Gorospe, E. C., Jan 1 2014, In : Annals of Gastroenterology. 27, 3, p. 193-199 7 p.

Research output: Contribution to journalArticle

Barrett Esophagus
Lasers
Endoscopy
Technology
Biopsy
1 Citation (Scopus)

Malignant mesothelioma presenting as dysphagia diagnosed by endoscopic ultrasound

Al-Bawardy, B., Gorospe, E. C. & Leggett, C., Jan 1 2014, In : Annals of Gastroenterology. 27, 4, 1 p.

Research output: Contribution to journalComment/debate

Deglutition Disorders
Malignant Mesothelioma
26 Citations (Scopus)

Obstructive sleep apnea is a risk factor for barrett's esophagus

Leggett, C., Gorospe, E. C., Calvin, A. D., Harmsen, W. S., Zinsmeister, A. R., Caples, S., Somers, V., Dunagan, K., Lutzke, L., Wang, K. K. N. & Iyer, P. G., 2014, In : Clinical Gastroenterology and Hepatology. 12, 4

Research output: Contribution to journalArticle

Barrett Esophagus
Obstructive Sleep Apnea
Gastroesophageal Reflux
Body Mass Index
Apnea
1 Citation (Scopus)

Recurrent bilateral pleural effusions without ascites as an initial presentation of Budd-Chiari syndrome

Desai, S. K., Al-Bawardy, B. F., Leggett, C. & Gorospe, E. C., Jan 1 2014, In : Annals of Gastroenterology. 27, 1, 1 p.

Research output: Contribution to journalComment/debate

Budd-Chiari Syndrome
Pleural Effusion
Ascites

Reply

Leggett, C. & Iyer, P. G., 2014, In : Clinical Gastroenterology and Hepatology. 12, 6, p. 1056 1 p.

Research output: Contribution to journalArticle

Barrett Esophagus
Obstructive Sleep Apnea
20 Citations (Scopus)

Volumetric laser endomicroscopy detects subsquamous barrett's Adenocarcinoma

Leggett, C., Gorospe, E., Owens, V. L., Anderson, M., Lutzke, L. & Wang, K. K. N., Feb 2014, In : American Journal of Gastroenterology. 109, 2, p. 298-299 2 p.

Research output: Contribution to journalArticle

Precancerous Conditions
Esophagoscopy
Barrett Esophagus
Catheter Ablation
Needle Biopsy
2013
8 Citations (Scopus)

A new era: Endoscopic tissue transplantation

Leggett, C., Gorospe, E. C., Lutzke, L., Anderson, M. & Wang, K. K. N., Sep 2013, In : Current Opinion in Gastroenterology. 29, 5, p. 495-500 6 p.

Research output: Contribution to journalArticle

Tissue Transplantation
Tissue Engineering
Gastrointestinal Endoscopy
Regeneration
Multipotent Stem Cells
10 Citations (Scopus)

Barrett's esophagus in 2012: updates in pathogenesis, treatment, and surveillance.

Chandra, S., Gorospe, E. C., Leggett, C. & Wang, K. K. N., May 2013, In : Current Gastroenterology Reports. 15, 5, p. 322 1 p.

Research output: Contribution to journalArticle

Barrett Esophagus
Adenocarcinoma
Therapeutics
Molecular Imaging
Gastroesophageal Reflux