• 58018 Citations
  • 116 Scopus h-Index
1976 …2020
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Research Output 1988 2020

2020
1 Citation (Scopus)
Open Access
Leukemia, Myelomonocytic, Chronic
Risk Management
Molecular Models
Mutation
decitabine

Chronic neutrophilic leukemia: 2020 update on diagnosis, molecular genetics, prognosis, and management

Szuber, N., Elliott, M. & Tefferi, A., Feb 1 2020, In : American journal of hematology. 95, 2, p. 212-224 13 p.

Research output: Contribution to journalArticle

Leukemia, Neutrophilic, Chronic
Molecular Biology
Colony-Stimulating Factor Receptors
Leukocytosis
Mutation
2019
6 Citations (Scopus)

3023 Mayo Clinic Patients With Myeloproliferative Neoplasms: Risk-Stratified Comparison of Survival and Outcomes Data Among Disease Subgroups

Szuber, N., Mudireddy, M., Nicolosi, M., Penna, D., Vallapureddy, R. R., Lasho, T. L., Finke, C., Begna, K., Elliott, M. A., Hook, C. C., Wolanskyj, A. P., Patnaik, M. M., Hanson, C. A., Ketterling, R. P., Sirhan, S., Pardanani, A. D., Gangat, N., Busque, L. & Tefferi, A., Jan 1 2019, In : Mayo Clinic proceedings.

Research output: Contribution to journalArticle

Polycythemia Vera
Essential Thrombocythemia
Primary Myelofibrosis
Survival
Neoplasms
1 Citation (Scopus)

A prospective evaluation of vitamin B1 (thiamine) level in myeloproliferative neoplasms: clinical correlations and impact of JAK2 inhibitor therapy

Gangat, N., Phelps, A., Lasho, T. L., Finke, C. M., Vallapureddy, R., Hanson, C. A., Ketterling, R. P., Patnaik, M. M., Pardanani, A. D. & Tefferi, A., Feb 1 2019, In : Blood Cancer Journal. 9, 2, 11.

Research output: Contribution to journalLetter

Thiamine
Neoplasms
Therapeutics
8 Citations (Scopus)

Aurora kinase A inhibition provides clinical benefit, normalizes megakaryocytes, and reduces bone marrow fibrosis in patients with myelofibrosis: A phase I trial

Gangat, N., Marinaccio, C., Swords, R., Watts, J. M., Gurbuxani, S., Rademaker, A., Fought, A. J., Frankfurt, O., Altman, J. K., Wen, Q. J., Farnoud, N., Famulare, C. A., Patel, A., Tapia, R., Vallapureddy, R. R., Barath, S., Graf, A., Handlogten, A., Zblewski, D., Patnaik, M. M. & 14 others, Al-Kali, A., Dinh, Y. T., Prahl, K. E., Patel, S., Nobrega, J. C., Tejera, D., Thomassen, A., Gao, J., Ji, P., Rampal, R. K., Giles, F. J., Tefferi, A., Stein, B. & Crispino, J. D., Aug 15 2019, In : Clinical Cancer Research. 25, 16, p. 4898-4906 9 p.

Research output: Contribution to journalArticle

Aurora Kinase A
Primary Myelofibrosis
Megakaryocytes
Fibrosis
Splenomegaly

Calculator-free point-of-care prognostication in myelodysplastic syndromes

Tefferi, A., Hanson, C. A., Ketterling, R. P., Pardanani, A. D. & Gangat, N., Jan 1 2019, (Accepted/In press) In : American Journal of Hematology.

Research output: Contribution to journalArticle

Point-of-Care Systems
Myelodysplastic Syndromes
1 Citation (Scopus)

Clinical, molecular, and prognostic correlates of number, type, and functional localization of TET2 mutations in chronic myelomonocytic leukemia (CMML)—a study of 1084 patients

Coltro, G., Mangaonkar, A. A., Lasho, T. L., Finke, C. M., Pophali, P., Carr, R., Gangat, N., Binder, M., Pardanani, A., Fernandez-Zapico, M., Robertson, K. D., Bosi, A., Droin, N., Vannucchi, A. M., Tefferi, A., Hunter, A., Padron, E., Solary, E. & Patnaik, M. M., Jan 1 2019, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

Leukemia, Myelomonocytic, Chronic
Mutation
5 Citations (Scopus)

Clinical correlates, prognostic impact and survival outcomes in chronic myelomonocytic leukemia patients with the JAK2V617F mutation

Patnaik, M. M., Pophali, P. A., Lasho, T. L., Finke, C. M., Horna, P., Ketterling, R. P., Gangat, N., Mangaonkar, A. A., Pardanani, A. D. & Tefferi, A., Jun 1 2019, In : Haematologica. 104, 6, p. e236-e239

Research output: Contribution to journalLetter

Open Access
Leukemia, Myelomonocytic, Chronic
Mutation
Survival

Comments on pre-fibrotic myelofibrosis and how should it be managed

Barbui, T., Thiele, J., Gisslinger, H., Orazi, A., Vannucchi, A. M., Gianelli, U., Beham-Schmid, C. & Tefferi, A., Jan 1 2019, In : British journal of haematology.

Research output: Contribution to journalLetter

Open Access
Essential Thrombocythemia
Primary Myelofibrosis

Correction to: Hybridization capture-based next-generation sequencing reliably detects FLT3 mutations and classifies FLT3-internal tandem duplication allelic ratio in acute myeloid leukemia: a comparative study to standard fragment analysis (Modern Pathology, (2019), 10.1038/s41379-019-0359-9)

He, R., Devine, D. J., Tu, Z. J., Mai, M., Chen, D., Nguyen, P. L., Oliveira, J. L., Hoyer, J. D., Reichard, K. K., Ollila, P. L., Al-Kali, A., Tefferi, A., Begna, K. H., Patnaik, M. M., Alkhateeb, H. & Viswanatha, D. S., Jan 1 2019, (Accepted/In press) In : Modern Pathology.

Research output: Contribution to journalComment/debate

Open Access
Licensure
Acute Myeloid Leukemia
Pathology
Mutation

Cutaneous blastic plasmacytoid dendritic cell neoplasm arising in the context of TET2 and ZRSR2 mutated clonal cytopenias of unknown significance, secondary to somatic copy number losses involving CDK2NA/2NB and MTAP

Li, M., Shah, M., Binder, M., Lasho, T., Carr, R., Mangaonkar, A., Gangat, N., Coltro, G., Tefferi, A., Dao, L., Peters, M., Chiu, A. & Patnaik, M. M., Jan 1 2019, (Accepted/In press) In : American journal of hematology.

Research output: Contribution to journalLetter

Open Access

Cytogenetic clonal evolution in myeloproliferative neoplasms: contexts and prognostic impact among 648 patients with serial bone marrow biopsies

Tefferi, A., Nicolosi, M., Penna, D., Vallapureddy, R., Hanson, C. A., Pardanani, A. D., Gangat, N. & Ketterling, R. P., Jan 1 2019, In : Leukemia.

Research output: Contribution to journalLetter

Clonal Evolution
Cytogenetics
Bone Marrow
Biopsy
Neoplasms

Essential thrombocythemia

Tefferi, A. & Pardanani, A., Nov 28 2019, In : New England Journal of Medicine. 381, 22, p. 2135-2144 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Etiologies of Extreme Thrombocytosis: A Contemporary Series

Hsieh, R. W., Ravindran, A., Hook, C. C., Begna, K., Ashrani, A. A., Pruthi, R. K., Marshall, A. L., Hogan, W., Litzow, M. R., Hoyer, J., Oliveira, J., Vishnu, P., Call, T. G., Al-Kali, A., Patnaik, M. M., Gangat, N., Pardanani, A. D., Tefferi, A. & Go, R. S., Aug 1 2019, In : Mayo Clinic proceedings. 94, 8, p. 1542-1550 9 p.

Research output: Contribution to journalArticle

Thrombocytosis
Hematologic Neoplasms
Outpatients
Inpatients
Splenectomy

Functional evaluation of isocitrate dehydrogenase 1 and 2 variants of unclear significance in chronic myeloid neoplasms

Tischer, A., Antelo, G., Coltro, G., Finke, C. M., Gonsalves, W., Pardanani, A., Ketterling, R., Mangaonkar, A., Gangat, N., Tefferi, A., Patnaik, M. M. & Lasho, T. L., Dec 2019, In : Leukemia Research. 87, 106264.

Research output: Contribution to journalLetter

Isocitrate Dehydrogenase
Neoplasms
Open Access
Thrombocytosis
Myelodysplastic Syndromes
Neoplasms

Hybridization capture-based next generation sequencing reliably detects FLT3 mutations and classifies FLT3-internal tandem duplication allelic ratio in acute myeloid leukemia: a comparative study to standard fragment analysis

He, R., Devine, D. J., Tu, Z. J., Mai, M., Chen, D., Nguyen, P. L., Oliveira, J., Hoyer, J., Reichard, K. K., Ollila, P. L., Al-Kali, A., Tefferi, A., Begna, K., Patnaik, M. M., Alkhateeb, H. & Viswanatha, D. S., Jan 1 2019, (Accepted/In press) In : Modern Pathology.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Mutation
4'-N-benzoylstaurosporine
United States Food and Drug Administration
Computational Biology

Leukemic transformation among 1306 patients with primary myelofibrosis: risk factors and development of a predictive model

Vallapureddy, R. R., Mudireddy, M., Penna, D., Lasho, T. L., Finke, C. M., Hanson, C. A., Ketterling, R. P., Begna, K., Gangat, N., Pardanani, A. D. & Tefferi, A., Feb 1 2019, In : Blood Cancer Journal. 9, 2, 12.

Research output: Contribution to journalArticle

Primary Myelofibrosis
Mutation
Anemia
Incidence
Karyotype
1 Citation (Scopus)

Outcome of Myelodysplastic Syndromes Over Time in the United States: A National Cancer Data Base Study From 2004-2013

Al-Kali, A., Zblewski, D., Foran, J. M., Patnaik, M. M., Larrabee, B. R., Gangat, N., Begna, K., Elliott, M. A., Hogan, W., Tefferi, A., Litzow, M. R. & Go, R. S., Aug 1 2019, In : Mayo Clinic proceedings. 94, 8, p. 1467-1474 8 p.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Databases
Neoplasms
Survival
Refractory Anemia with Excess of Blasts
3 Citations (Scopus)

Practical limitations of monocyte subset repartitioning by multiparametric flow cytometry in chronic myelomonocytic leukemia

Pophali, P. A., Timm, M. M., Mangaonkar, A. A., Shi, M., Reichard, K., Tefferi, A., Pavelko, K., Villasboas Bisneto, J. J. C. ., Jevremovic, D. & Patnaik, M. M., Sep 1 2019, In : Blood cancer journal. 9, 9, 65.

Research output: Contribution to journalLetter

Open Access
Leukemia, Myelomonocytic, Chronic
Monocytes
Flow Cytometry
6 Citations (Scopus)
Refractory Anemia
Thrombocytosis
Myelodysplastic Syndromes
Risk Management
Mutation
8 Citations (Scopus)

Suboptimal response rates to hypomethylating agent therapy in chronic myelomonocytic leukemia; a single institutional study of 121 patients

Coston, T., Pophali, P., Vallapureddy, R., Lasho, T. L., Finke, C. M., Ketterling, R. P., Carr, R., Binder, M., Mangaonkar, A. A., Gangat, N., Al-Kali, A., Litzow, M. R., Zblewski, D., Pardanani, A. D., Tefferi, A. & Patnaik, M. M., Jan 1 2019, In : American journal of hematology.

Research output: Contribution to journalArticle

Leukemia, Myelomonocytic, Chronic
Myelodysplastic Syndromes
decitabine
Survival
Therapeutics
1 Citation (Scopus)

World Health Organization class-independent risk categorization in mastocytosis

Pardanani, A. D., Lasho, T. L., Reichard, K. K., Hanson, C. A. & Tefferi, A., Mar 1 2019, In : Blood cancer journal. 9, 3, 29.

Research output: Contribution to journalLetter

Open Access
Mastocytosis
2018

20+ Years and alive with primary myelofibrosis: Phenotypic signature of very long-lived patients

Penna, D., Lasho, T. L., Finke, C. M., Vallapureddy, R. R., Hanson, C. A., Ketterling, R. P., Pardanani, A. D., Gangat, N. & Tefferi, A., Jan 1 2018, (Accepted/In press) In : American Journal of Hematology.

Research output: Contribution to journalArticle

Primary Myelofibrosis
Survival
Platelet Count
Leukocyte Count
Genetic Markers
10 Citations (Scopus)

A comparison of clinical and molecular characteristics of patients with systemic mastocytosis with chronic myelomonocytic leukemia to CMML alone

Patnaik, M. M., Rangit Vallapureddy, V., Lasho, T. L., Hoversten, K. P., Finke, C. M., Ketterling, R. P., Hanson, C. A., Gangat, N., Tefferi, A. & Pardanani, A. D., Apr 2 2018, (Accepted/In press) In : Leukemia. p. 1-6 6 p.

Research output: Contribution to journalArticle

Leukemia, Myelomonocytic, Chronic
Systemic Mastocytosis

AKT activation is a feature of CALR mutant myeloproliferative neoplasms

Fu, C., Wen, Q. J., Marinaccio, C., Ling, T., Chen, W., Bulic, M., Lasho, T., Tefferi, A., Crispino, J. D. & Xu, K., Jan 1 2018, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

Neoplasms
9 Citations (Scopus)
Primary Myelofibrosis
Hematopoietic Stem Cells
Karyotype
Transplants
Survival
1 Citation (Scopus)

A novel predictive model of outcome in acute myeloid leukemia without favorable karyotype based on treatment strategy, karyotype and FLT3-ITD mutational status

Begna, K., Ali, W., Gangat, N., Elliott, M. A., Al-Kali, A., Litzow, M. R., Hook, C. C., Wolanskyj, A. P., Hogan, W., Patnaik, M. M., Pardanani, A. D., Zblewski, D. L., Chen, D., He, R., Viswanatha, D., Hanson, C. A., Ketterling, R. P. & Tefferi, A., Jan 1 2018, (Accepted/In press) In : American Journal of Hematology.

Research output: Contribution to journalArticle

Karyotype
Acute Myeloid Leukemia

A retrospective survey of exposure history to chemotherapy or radiotherapy in 940 consecutive patients with primary myelofibrosis

Nicolosi, M., Mudireddy, M., Patnaik, M. M., Gangat, N., Pardanani, A. D. & Tefferi, A., Apr 1 2018, In : American Journal of Hematology. 93, 4, p. E103-E107

Research output: Contribution to journalLetter

Primary Myelofibrosis
Radiotherapy
History
Drug Therapy
Surveys and Questionnaires

Association Between Renal Cell Carcinoma and Myelodysplastic Syndromes: Epigenetic Underpinning?

Shenoy, N., Mudireddy, M., Vallapureddy, R., Leung, N., Pagliaro, L., Witzig, T. E., Ou, F-S., Ordog, T., Cheville, J., Patnaik, M. M., Thompson, R. H., Tefferi, A. & Begna, K., Jan 1 2018, (Accepted/In press) In : Clinical Genitourinary Cancer.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Renal Cell Carcinoma
Epigenomics
Nephrectomy
Population

Atypical Phenotype and Treatment Response Pattern in a Patient with FIP1L1-PDGFRα Mutation

Bikhchandani, M., Johnson, R., Tuan, B. & Tefferi, A., Jan 1 2018, (Accepted/In press) In : Acta Haematologica. p. 67-70 4 p.

Research output: Contribution to journalArticle

Eosinophilia
Phenotype
Mutation
Acute Myeloid Leukemia
Bone Marrow
3 Citations (Scopus)

Biallelic inactivation of the retinoblastoma gene results in transformation of chronic myelomonocytic leukemia to a blastic plasmacytoid dendritic cell neoplasm: shared clonal origins of two aggressive neoplasms

Patnaik, M. M., Lasho, T., Howard, M., Finke, C., Ketterling, R. L., Al-Kali, A., Pardanani, A. D., Droin, N., Gangat, N., Tefferi, A. & Solary, E., Sep 1 2018, In : Blood Cancer Journal. 8, 9, 82.

Research output: Contribution to journalLetter

Leukemia, Myelomonocytic, Chronic
Retinoblastoma Genes
Dendritic Cells
Neoplasms
9 Citations (Scopus)

Blast phase chronic myelomonocytic leukemia: Mayo-MDACC collaborative study of 171 cases

Patnaik, M. M., Pierola, A. A., Vallapureddy, R., Yalniz, F. F., Kadia, T. M., Jabbour, E. J., Lasho, T., Hanson, C. A., Ketterling, R. P., Kantarjian, H. M., Tefferi, A. & Garcia-Manero, G., Apr 25 2018, (Accepted/In press) In : Leukemia. p. 1-7 7 p.

Research output: Contribution to journalArticle

Leukemia, Myelomonocytic, Chronic
Blast Crisis
1 Citation (Scopus)

Blast-phase chronic myelomonocytic leukemia: more than just semantics

Patnaik, M. M., Tefferi, A. & Garcia-Manero, G., Sep 1 2018, In : Leukemia. 32, 9, p. 2093-2094 2 p.

Research output: Contribution to journalLetter

Leukemia, Myelomonocytic, Chronic
Blast Crisis
Semantics
16 Citations (Scopus)

Blast phase myeloproliferative neoplasm: Mayo-AGIMM study of 410 patients from two separate cohorts

Tefferi, A., Mudireddy, M., Mannelli, F., Begna, K., Patnaik, M. M., Hanson, C. A., Ketterling, R. P., Gangat, N., Yogarajah, M., de Stefano, V., Passamonti, F., Rosti, V., Finazzi, M. C., Rambaldi, A., Bosi, A., Guglielmelli, P., Pardanani, A. D. & Vannucchi, A. M., Feb 2 2018, (Accepted/In press) In : Leukemia. p. 1-11 11 p.

Research output: Contribution to journalArticle

Blast Crisis
Stem Cells
Transplants
Survival
Neoplasms
26 Citations (Scopus)
Leukemia, Myelomonocytic, Chronic
Risk Management
Molecular Models
Mutation
decitabine
7 Citations (Scopus)

Chronic neutrophilic leukemia: 2018 update on diagnosis, molecular genetics and management

Elliott, M. A. & Tefferi, A., Apr 1 2018, In : American Journal of Hematology. 93, 4, p. 578-587 10 p.

Research output: Contribution to journalArticle

Leukemia, Neutrophilic, Chronic
Molecular Biology
Mutation
Neutrophils
Neoplasms
3 Citations (Scopus)

Chronic neutrophilic leukemia: New science and new diagnostic criteria

Szuber, N. & Tefferi, A., Feb 1 2018, In : Blood Cancer Journal. 8, 2, 19.

Research output: Contribution to journalReview article

Leukemia, Neutrophilic, Chronic
Mutation
Splenomegaly
Granulocytes
Hyperplasia
2 Citations (Scopus)

CSF3R-mutated chronic neutrophilic leukemia: Long-term outcome in 19 consecutive patients and risk model for survival

Szuber, N., Finke, C. M., Lasho, T. L., Elliott, M. A., Hanson, C. A., Pardanani, A. D. & Tefferi, A., Feb 1 2018, In : Blood Cancer Journal. 8, 2, 21.

Research output: Contribution to journalLetter

Leukemia, Neutrophilic, Chronic
Survival
3 Citations (Scopus)

Cytogenetic abnormalities in systemic mastocytosis: WHO subcategory-specific incidence and prognostic impact among 348 informative cases

Shah, S., Pardanani, A. D., Elala, Y. C., Lasho, T. L., Patnaik, M. M., Reichard, K. K., Hanson, C. A., Ketterling, R. P. & Tefferi, A., Jan 1 2018, (Accepted/In press) In : American Journal of Hematology.

Research output: Contribution to journalArticle

Systemic Mastocytosis
Chromosome Aberrations
Incidence
Abnormal Karyotype
Mast-Cell Leukemia
6 Citations (Scopus)

Cytogenetic findings in WHO-defined polycythaemia vera and their prognostic relevance

Barraco, D., Cerquozzi, S., Hanson, C. A., Ketterling, R. P., Pardanani, A. D., Gangat, N. & Tefferi, A., Aug 1 2018, In : British Journal of Haematology. 182, 3, p. 437-440 4 p.

Research output: Contribution to journalLetter

Polycythemia Vera
Cytogenetics

Decreased survival and increased rate of fibrotic progression in essential thrombocythemia chronicled after the FDA approval date of anagrelide

Tefferi, A., Szuber, N., Vallapureddy, R. R., Begna, K., Patnaik, M. M., Elliott, M. A., Christopher Hook, C., Wolanskyj, A. P., Hanson, C. A., Ketterling, R. P., Pardanani, A. D. & Gangat, N., Jan 1 2018, (Accepted/In press) In : American Journal of Hematology.

Research output: Contribution to journalArticle

Essential Thrombocythemia
Survival Rate
Primary Myelofibrosis
Survival
Busulfan

Determinants of long-term outcome in type 1 calreticulin-mutated myelofibrosis

Szuber, N., Lasho, T. L., Finke, C., Hanson, C. A., Ketterling, R. P., Pardanani, A. D., Gangat, N. & Tefferi, A., Jan 1 2018, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

Calreticulin
Primary Myelofibrosis
2 Citations (Scopus)

Development of a prognostically relevant cachexia index in primary myelofibrosis using serum albumin and cholesterol levels

Tefferi, A., Nicolosi, M., Penna, D., Mudireddy, M., Szuber, N., Lasho, T. L., Hanson, C. A., Ketterling, R. P., Gangat, N. & Pardanani, A. D., Aug 14 2018, In : Blood Advances. 2, 15, p. 1980-1984 5 p.

Research output: Contribution to journalArticle

Open Access
Primary Myelofibrosis
Cachexia
Serum Albumin
Cholesterol
4 Citations (Scopus)

Driver mutations in primary myelofibrosis and their implications

Szuber, N. & Tefferi, A., Mar 1 2018, In : Current Opinion in Hematology. 25, 2, p. 129-135 7 p.

Research output: Contribution to journalReview article

Primary Myelofibrosis
Mutation
Calreticulin
Janus Kinase 2
Neoplasms
2 Citations (Scopus)

Early thrombotic events and preemptive systemic anticoagulation following splenectomy for myelofibrosis

Mudireddy, M., Gangat, N., Lasho, T. L., Finke, C., Hanson, C. A., Ketterling, R. P., Ashrani, A. A., Pardanani, A. D., Nagorney, D. M. & Tefferi, A., Jan 1 2018, (Accepted/In press) In : American Journal of Hematology.

Research output: Contribution to journalArticle

Primary Myelofibrosis
Splenectomy
17 Citations (Scopus)

Essential thrombocythemia treatment algorithm 2018

Tefferi, A., Vannucchi, A. M. & Barbui, T., Jan 1 2018, In : Blood Cancer Journal. 8, 1, 2.

Research output: Contribution to journalArticle

Essential Thrombocythemia
Polycythemia Vera
Thrombosis
Mutation
Therapeutics
2 Citations (Scopus)

Extramedullary hematopoiesis in the absence of myeloproliferative neoplasm: Mayo Clinic case series of 309 patients

Fan, N., Lavu, S., Hanson, C. A. & Tefferi, A., Nov 19 2018, In : Blood Cancer Journal. 8, 12, 1 p.

Research output: Contribution to journalArticle

Extramedullary Hematopoiesis
Neoplasms
11 Citations (Scopus)

EZH2 mutations in chronic myelomonocytic leukemia cluster with ASXL1 mutations and their co-occurrence is prognostically detrimental

Patnaik, M. M., Vallapureddy, R., Lasho, T. L., Hoversten, K. P., Finke, C. M., Ketterling, R., Hanson, C., Gangat, N. & Tefferi, A., Jan 1 2018, In : Blood Cancer Journal. 8, 1, 12.

Research output: Contribution to journalLetter

Leukemia, Myelomonocytic, Chronic
Mutation
1 Citation (Scopus)

FGFR1 rearranged hematological neoplasms – molecularly defined and clinically heterogeneous

Patnaik, M. M., Ketterling, R. P. & Tefferi, A., Feb 1 2018, (Accepted/In press) In : Leukemia and Lymphoma. p. 1-3 3 p.

Research output: Contribution to journalArticle

Hematologic Neoplasms