Anne J Novak, PhD

  • 5614 Citations
  • 40 Scopus h-Index
20022019
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Research Output 2002 2019

  • 5614 Citations
  • 40 Scopus h-Index
  • 98 Article
  • 3 Letter
  • 2 Chapter
  • 2 Comment/debate
Article
60 Citations (Scopus)

A BAFF-R mutation associated with non-Hodgkin lymphoma alters TRAF recruitment and reveals new insights into BAFF-R signaling

Hildebrand, J. M., Luo, Z., Manske, M. K., Price-Troska, T., Ziesmer, S. C., Lin, W., Hostager, B. S., Slager, S. L., Witzig, T. E., Ansell, S. M., Cerhan, J. R., Bishop, G. A. & Novak, A. J., Nov 22 2010, In : Journal of Experimental Medicine. 207, 12, p. 2569-2579 11 p.

Research output: Contribution to journalArticle

B-Cell Activation Factor Receptor
Non-Hodgkin's Lymphoma
Mutation
TNF Receptor-Associated Factor 6
TNF Receptor-Associated Factor 3
190 Citations (Scopus)
B-Cell Activating Factor
B-Cell Chronic Lymphocytic Leukemia
Cells
Survival
B-Lymphocytes
50 Citations (Scopus)

Activation of TAK1 by MYD88 L265P drives malignant B-cell growth in non-Hodgkin lymphoma

Ansell, S. M., Hodge, L. S., Secreto, F. J., Manske, M., Braggio, E. D., Price-Troska, T., Ziesmer, S., Li, Y., Johnson, S. H., Hart, S., Kocher, J-P., Vasmatzis, G., Chanan Khan, A. A., Gertz, M., Fonseca, R., Dogan, A., Cerhan, J. R. & Novak, A. J., 2014, In : Blood Cancer Journal. 4, 2, 20144.

Research output: Contribution to journalArticle

Waldenstrom Macroglobulinemia
Non-Hodgkin's Lymphoma
B-Lymphocytes
Growth
TNF Receptor-Associated Factor 6
30 Citations (Scopus)

A genome-wide association study of marginal zone lymphoma shows association to the HLA region

Vijai, J., Wang, Z., Berndt, S. I., Skibola, C. F., Slager, S. L., De Sanjose, S., Melbye, M., Glimelius, B., Bracci, P. M., Conde, L., Birmann, B. M., Wang, S. S., Brooks-Wilson, A. R., Lan, Q., De Bakker, P. I. W., Vermeulen, R. C. H., Portlock, C., Ansell, S. M., Link, B. K., Riby, J. & 82 others, North, K. E., Gu, J., Hjalgrim, H., Cozen, W., Becker, N., Teras, L. R., Spinelli, J. J., Turner, J., Zhang, Y., Purdue, M. P., Giles, G. G., Kelly, R. S., Zeleniuch-Jacquotte, A., Ennas, M. G., Monnereau, A., Bertrand, K. A., Albanes, D., Lightfoot, T., Yeager, M., Chung, C. C., Burdett, L., Hutchinson, A., Lawrence, C., Montalvan, R., Liang, L., Huang, J., Ma, B., Villano, D. J., Maria, A., Corines, M., Thomas, T., Novak, A. J., Dogan, A., Liebow, M., Thompson, C. A., Witzig, T. E., Habermann, T. M., Weiner, G. J., Smith, M. T., Holly, E. A., Jackson, R. D., Tinker, L. F., Ye, Y., Adami, H. O., Smedby, K. E., De Roos, A. J., Hartge, P., Morton, L. M., Severson, R. K., Benavente, Y., Boffetta, P., Brennan, P., Foretova, L., Maynadie, M., McKay, J., Staines, A., DIver, W. R., Vajdic, C. M., Armstrong, B. K., Kricker, A., Zheng, T., Holford, T. R., Severi, G., Vineis, P., Ferri, G. M., Ricco, R., Miligi, L., Clavel, J., Giovannucci, E., Kraft, P., Virtamo, J., Smith, A., Kane, E., Roman, E., Chiu, B. C. H., Fraumeni, J. F., Wu, X., Cerhan, J. R., Offit, K., Chanock, S. J., Rothman, N. & Nieters, A., Jan 8 2015, In : Nature Communications. 6, 6751.

Research output: Contribution to journalArticle

HLA-B Antigens
genome
Genome-Wide Association Study
loci
Lymphoma

Amplification of 9p24.1 in diffuse large B-cell lymphoma identifies a unique subset of cases that resemble primary mediastinal large B-cell lymphoma

Wang, Y., Wenzl, K., Manske, M. K., Asmann, Y., Sarangi, V., Greipp, P. T., Krull, J. E., Hartert, K., He, R., Feldman, A. L., Maurer, M. J., Slager, S. L., Nowakowski, G. S., Habermann, T. M., Witzig, T. E., Link, B. K., Ansell, S. M., Cerhan, J. R. & Novak, A. J., Sep 1 2019, In : Blood cancer journal. 9, 9, 73.

Research output: Contribution to journalArticle

Open Access
Lymphoma, Large B-Cell, Diffuse
B-Cell Lymphoma
Immunotherapy
Lymphoma
Hodgkin Disease
69 Citations (Scopus)

Analysis of heritability and shared heritability based on genome-wide association studies for thirteen cancer types

Sampson, J. N., Wheeler, W. A., Yeager, M., Panagiotou, O., Wang, Z., Berndt, S. I., Lan, Q., Abnet, C. C., Amundadottir, L. T., Figueroa, J. D., Landi, M. T., Mirabello, L., Savage, S. A., Taylor, P. R., De Vivo, I., McGlynn, K. A., Purdue, M. P., Rajaraman, P., Adami, H. O., Ahlbom, A. & 388 others, Albanes, D., Amary, M. F., An, S. J., Andersson, U., Andriole, G., Andrulis, I. L., Angelucci, E., Ansell, S. M., Arici, C., Armstrong, B. K., Arslan, A. A., Austin, M. A., Baris, D., Barkauskas, D. A., Bassig, B. A., Becker, N., Benavente, Y., Benhamou, S., Berg, C., Van Den Berg, D., Bernstein, L., Bertrand, K. A., Birmann, B. M., Black, A., Shanafelt, T. D., Boffetta, P., Boutron-Ruault, M. C., Bracci, P. M., Brinton, L., Brooks-Wilson, A. R., Bueno-De-Mesquita, H. B., Burdett, L., Buring, J., Butler, M. A., Cai, Q., Cancel-Tassin, G., Canzian, F., Carrato, A., Carreon, T., Carta, A., Chan, J. K. C., Chang, E. T., Chang, G. C., Chang, I. S., Chang, J., Chang-Claude, J., Chen, C. J., Chen, C. Y., Chen, C., Chen, C. H., Chen, C., Chen, H., Chen, K., Chen, K. Y., Chen, K. C., Chen, Y., Chen, Y. H., Chen, Y. S., Chen, Y. M., Chien, L. H., Chirlaque, M. D., Choi, J. E., Choi, Y. Y., Chow, W. H., Chung, C. C., Clavel, J., Clavel-Chapelon, F., Cocco, P., Colt, J. S., Comperat, E., Conde, L., Connors, J. M., Conti, D., Cortessis, V. K., Cotterchio, M., Cozen, W., Crouch, S., Crous-Bou, M., Cussenot, O., Davis, F. G., Ding, T., Diver, W. R., Dorronsoro, M., Dossus, L., Duell, E. J., Ennas, M. G., Erickson, R. L., Feychting, M., Flanagan, A. M., Foretova, L., Fraumeni, J. F., Freedman, N. D., Freeman, L. E. B., Fuchs, C., Gago-Dominguez, M., Gallinger, S., Gao, Y. T., Gapstur, S. M., Garcia-Closas, M., García-Closas, R., Gascoyne, R. D., Gastier-Foster, J., Gaudet, M. M., Gaziano, J. M., Giffen, C., Giles, G. G., Giovannucci, E., Glimelius, B., Goggins, M., Gokgoz, N., Goldstein, A. M., Gorlick, R., Gross, M., Grubb, R., Gu, J., Guan, P., Gunter, M., Guo, H., Habermann, T. M., Haiman, C. A., Halai, D., Hallmans, G., Hassan, M., Hattinger, C., He, Q., He, X., Helzlsouer, K., Henderson, B., Henriksson, R., Hjalgrim, H., Hoffman-Bolton, J., Hohensee, C., Holford, T. R., Holly, E. A., Hong, Y. C., Hoover, R. N., Horn-Ross, P. L., Hosain, G. M. M., Hosgood, H. D., Hsiao, C. F., Hu, N., Hu, W., Hu, Z., Huang, M. S., Huerta, J. M., Hung, J. Y., Hutchinson, A., Inskip, P. D., Jackson, R. D., Jacobs, E. J., Jenab, M., Jeon, H. S., Ji, B. T., Jin, G., Jin, L., Johansen, C., Johnson, A., Jung, Y. J., Kaaks, R., Kamineni, A., Kane, E., Kang, C. H., Karagas, M. R., Kelly, R. S., Khaw, K. T., Kim, C., Kim, H. N., Kim, J. H., Kim, J. S., Kim, Y. H., Kim, Y. T., Kim, Y. C., Kitahara, C. M., Klein, A. P., Klein, R. J., Kogevinas, M., Kohno, T., Kolonel, L. N., Kooperberg, C., Kricker, A., Krogh, V., Kunitoh, H., Kurtz, R. C., Kweon, S. S., La Croix, A., Lawrence, C., Lecanda, F., Lee, V. H. F., Li, D., Li, H., Li, J., Li, Y. J., Li, Y., Liao, L. M., Liebow, M., Lightfoot, T., Lim, W. Y., Lin, C. C., Lin, D., Lindstrom, S., Linet, M. S., Link, B. K., Liu, C., Liu, J., Liu, L., Ljungberg, B., Lloreta, J., Di Lollo, S., Lu, D., Lund, E., Malats, N., Mannisto, S., Marchand, L. L., Marina, N., Masala, G., Mastrangelo, G., Matsuo, K., Maynadie, M., McKay, J., McKean-Cowdin, R., Melbye, M., Melin, B. S., Michaud, D. S., Mitsudomi, T., Monnereau, A., Montalvan, R., Moore, L. E., Mortensen, L. M., Nieters, A., North, K. E., Novak, A. J., Oberg, A. L., Offit, K., Oh, I. J., Olson, S. H., Palli, D., Pao, W., Park, I. K., Park, J. Y., Park, K. H., Patiño-Garcia, A., Pavanello, S., Peeters, P. H. M., Perng, R. P., Peters, U., Petersen, G. M., Picci, P., Pike, M. C., Porru, S., Prescott, J., Prokunina-Olsson, L., Qian, B., Qiao, Y. L., Rais, M., Riboli, E., Riby, J., Risch, H. A., Rizzato, C., Rodabough, R., Roman, E., Roupret, M., Ruder, A. M., De Sanjose, S., Scelo, G., Schned, A., Schumacher, F., Schwartz, K., Schwenn, M., Scotlandi, K., Seow, A., Serra, C., Serra, M., Sesso, H. D., Setiawan, V. W., Severi, G., Severson, R. K., Shanafelt, T. D., Shen, H., Shen, W., Shin, M. H., Shiraishi, K., Shu, X. O., Siddiq, A., Sierrasesúmaga, L., Sihoe, A. D. L., Skibola, C. F., Smith, A., Smith, M. T., Southey, M. C., Spinelli, J. J., Staines, A., Stampfer, M., Stern, M. C., Stevens, V. L., Stolzenberg-Solomon, R. S., Su, J., Su, W. C., Sund, M., Sung, J. S., Sung, S. W., Tan, W., Tang, W., Tardón, A., Thomas, D., Thompson, C. A., Tinker, L. F., Tirabosco, R., Tjønneland, A., Travis, R. C., Trichopoulos, D., Tsai, F. Y., Tsai, Y. H., Tucker, M., Turner, J., Vajdic, C. M., Vermeulen, R. C. H., Villano, D. J., Vineis, P., Virtamo, J., Visvanathan, K., Wactawski-Wende, J., Wang, C., Wang, C. L., Wang, J. C., Wang, J., Wei, F., Weiderpass, E., Weiner, G. J., Weinstein, S., Wentzensen, N., White, E., Witzig, T. E., Wolpin, B. M., Wong, M. P., Wu, C., Wu, G., Wu, J., Wu, T., Wu, W., Wu, X., Wu, Y. L., Wunder, J. S., Xiang, Y. B., Xu, J., Xu, P., Yang, P. C., Yang, T. Y., Ye, Y., Yin, Z., Yokota, J., Yoon, H. I., Yu, C. J., Yu, H., Yu, K., Yuan, J. M., Zelenetz, A., Zeleniuch-Jacquotte, A., Zhang, X. C., Zhang, Y., Zhao, X., Zhao, Z., Zheng, H., Zheng, T., Zheng, W., Zhou, B., Zhu, M., Zucca, M., Boca, S. M., Cerhan, J. R., Ferri, G. M., Hartge, P., Hsiung, C. A., Magnani, C., Miligi, L., Morton, L. M., Smedby, K. E., Teras, L. R., Vijai, J., Wang, S. S., Brennan, P., Caporaso, N. E., Hunter, D. J., Kraft, P., Rothman, N., Silverman, D. T., Slager, S. L., Chanock, S. J. & Chatterjee, N., 2016, In : Journal of the National Cancer Institute. 107, 12, djv279.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Smoking
Neoplasms
Lung Neoplasms
Confidence Intervals
245 Citations (Scopus)

An APRIL to remember: Novel TNF ligands as therapeutic targets

Dillon, S. R., Gross, J. A., Ansell, S. M. & Novak, A. J., Mar 2006, In : Nature Reviews Drug Discovery. 5, 3, p. 235-246 12 p.

Research output: Contribution to journalArticle

Ligands
Autoimmunity
B-Lymphocytes
Therapeutics
Neoplasms
39 Citations (Scopus)
Phosphatidylinositol 3-Kinase
Follicular Lymphoma
Cyclin D1
Cell proliferation
Sirolimus
16 Citations (Scopus)

A role for IFN-λ1 in multiple myeloma B cell growth

Novak, A. J., Grote, D. M., Ziesmer, S. C., Rajkumar, S. V., Doyle, S. E. & Ansell, S. M., 2008, In : Leukemia. 22, 12, p. 2240-2246 7 p.

Research output: Contribution to journalArticle

Multiple Myeloma
Interferons
B-Lymphocytes
Growth
Cytokines
4 Citations (Scopus)
Immunosuppression
Monocytes
Lymphoma
Cytokines
Lymphocytes
122 Citations (Scopus)

Attenuation of CD8+ T-cell function by CD4+CD25 + regulatory T cells in B-cell non-Hodgkin's lymphoma

Yang, Z. Z., Novak, A. J., Ziesmer, S. C., Witzig, T. E. & Ansell, S. M., Oct 15 2006, In : Cancer Research. 66, 20, p. 10145-10152 8 p.

Research output: Contribution to journalArticle

B-Cell Lymphoma
Regulatory T-Lymphocytes
Non-Hodgkin's Lymphoma
T-Lymphocytes
Cell Proliferation
16 Citations (Scopus)
Non-Hodgkin's Lymphoma
Single Nucleotide Polymorphism
Inflammation
Confidence Intervals
Genes
131 Citations (Scopus)

B7-H1 (PD-L1, CD274) suppresses host immunity in T-cell lymphoproliferative disorders

Wilcox, R. A., Feldman, A. L., Wada, D. A., Yang, Z. Z., Comfere, N. I., Dong, H. M., Kwon, E. D., Novak, A. J., Markovic, S. N., Pittelkow, M. R., Witzig, T. E. & Ansell, S. M., 2009, In : Blood. 114, 10, p. 2149-2158 10 p.

Research output: Contribution to journalArticle

T-cells
Lymphoproliferative Disorders
Non-Hodgkin's Lymphoma
Tumor Microenvironment
Immunity
5 Citations (Scopus)

B-cell activating factor-receptor specific activation of tumor necrosis factor receptor associated factor 6 and the phosphatidyl inositol 3-kinase pathway in lymphoma B cells

Secreto, F., Manske, M., Price-Troska, T., Ziesmer, S., Hodge, L. S., Ansell, S. M., Cerhan, J. R. & Novak, A. J., 2014, In : Leukemia and Lymphoma. 55, 8, p. 1884-1892 9 p.

Research output: Contribution to journalArticle

B-Cell Activation Factor Receptor
Tumor Necrosis Factor Receptor-Associated Peptides and Proteins
Interleukin-4 Receptors
B-Cell Lymphoma
Phosphatidylinositols
55 Citations (Scopus)

BCL2 mutations are associated with increased risk of transformation and shortened survival in follicular lymphoma

Correia, C., Schneider, P. A., Dai, H., Dogan, A., Maurer, M. J., Church, A. K., Novak, A. J., Feldman, A. L., Wu, X., Ding, H., Meng, X. W., Cerhan, J. R., Slager, S. L., Macon, W. R., Habermann, T. M., Karp, J. E., Gore, S. D., Kay, N. E., Jelinek, D. F., Witzig, T. E. & 2 others, Nowakowski, G. S. & Kaufmann, S. H., Jan 22 2015, In : Blood. 125, 4, p. 658-667 10 p.

Research output: Contribution to journalArticle

Follicular Lymphoma
Mutation
Lymphoma
Immunoglobulins
Hazards
76 Citations (Scopus)

B-lymphocyte stimulator (BLyS) stimulates immunoglobulin production and malignant B-cell growth in Waldenström macroglobulinemia

Elsawa, S. F., Novak, A. J., Grote, D. M., Ziesmer, S. C., Witzig, T. E., Kyle, R. A., Dillon, S. R., Harder, B., Gross, J. A. & Ansell, S. M., Apr 1 2006, In : Blood. 107, 7, p. 2882-2888 7 p.

Research output: Contribution to journalArticle

B-Cell Activating Factor
Waldenstrom Macroglobulinemia
Cell growth
Immunoglobulins
B-Lymphocytes
68 Citations (Scopus)
Integrin alpha4beta1
B-Cell Lymphoma
Mesenchymal Stromal Cells
Integrins
Apoptosis
126 Citations (Scopus)

CD70+ non-Hodgkin lymphoma B cells induce Foxp3 expression and regulatory function in intratumoral CD4+CD25- T cells

Yang, Z. Z., Novak, A. J., Ziesmer, S. C., Witzig, T. E. & Ansell, S. M., Oct 1 2007, In : Blood. 110, 7, p. 2537-2544 8 p.

Research output: Contribution to journalArticle

T-cells
Non-Hodgkin's Lymphoma
B-Lymphocytes
Cells
T-Lymphocytes
5 Citations (Scopus)

CDDO-imidazolide mediated inhibition of malignant cell growth in Waldenström macroglobulinemia

Elsawa, S. F., Novak, A. J., Grote, D., Konopleva, M., Andreeff, M., Witzig, T. E. & Ansell, S. M., Dec 2008, In : Leukemia Research. 32, 12, p. 1895-1902 8 p.

Research output: Contribution to journalArticle

Waldenstrom Macroglobulinemia
Growth
B-Lymphocytes
Cell Death
Neoplasms
2 Citations (Scopus)

Clinical, histopathological, and molecular features of mucosa-associated lymphoid tissue (MALT) lymphoma carrying the t(X;14) (p11;q32)/GPR34-immunoglobulin heavy chain gene

Akasaka, T., Lee, Y. F., Novak, A. J., Honjo, G., Takeoka, K., Maekawa, F., Fukutsuka, K., Hayashida, M. & Ohno, H., Feb 27 2017, (Accepted/In press) In : Leukemia and Lymphoma. p. 1-4 4 p.

Research output: Contribution to journalArticle

Immunoglobulin Heavy Chain Genes
Marginal Zone B-Cell Lymphoma
17 Citations (Scopus)
cohort analysis
disease incidence
Molecular Epidemiology
epidemiology
research program
15 Citations (Scopus)

Coinhibition of the deubiquitinating enzymes, USP14 and UCHL5, with VLX1570 is lethal to ibrutinib- or bortezomib-resistant Waldenstrom macroglobulinemia tumor cells

Paulus, A., Akhtar, S., Caulfield, T., Samuel, K., Yousaf, H., Bashir, Y., Paulus, S. M., Tran, D., Hudec, R., Cogen, D., Jiang, J., Edenfield, B., Novak, A. J., Ansell, S. M., Witzig, T. E., Martin, P., Coleman, M., Roy, V., Ailawadhi, S., Chitta, K. & 2 others, Linder, S. & Chanan Khan, A. A., Nov 4 2016, In : Blood Cancer Journal. 6, 11, e492.

Research output: Contribution to journalArticle

Ubiquitin-Specific Proteases
Waldenstrom Macroglobulinemia
Hydrolases
Ubiquitin
Isoenzymes
11 Citations (Scopus)

Common variants within 6p21.31 locus are associated with chronic lymphocytic leukaemia and, potentially, other non-Hodgkin lymphoma subtypes

Slager, S. L., Camp, N. J., Conde, L., Shanafelt, T. D., Achenbach, S. J., Rabe, K. G., Kay, N. E., Novak, A. J., Call, T. G., Bracci, P. M., Sille, F. M. C., Sanchez, S., Akers, N. K., Cunningham, J. M., Serie, D. J., McDonnell, S. K., Leis, J. F., Wang, A. H., Weinberg, J. B., Glenn, M. & 5 others, Link, B., Vachon, C. M., Lanasa, M. C., Skibola, C. F. & Cerhan, J. R., Dec 2012, In : British Journal of Haematology. 159, 5, p. 572-576 5 p.

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
Non-Hodgkin's Lymphoma
Genome-Wide Association Study
Meta-Analysis
50 Citations (Scopus)

Comprehensive analysis of tumor microenvironment cytokines in Waldenstrom macroglobulinemia identifies CCL5 as a novel modulator of IL-6 activity

Elsawa, S. F., Novak, A. J., Ziesmer, S. C., Almada, L. L., Hodge, L. S., Grote, D. M., Witzig, T. E., Fernandez-Zapico, M. E. & Ansell, S. M., Nov 17 2011, In : Blood. 118, 20, p. 5540-5549 10 p.

Research output: Contribution to journalArticle

Waldenstrom Macroglobulinemia
Tumor Microenvironment
Modulators
Immunoglobulin M
Tumors
11 Citations (Scopus)

Constitutive activation of STAT5A and STAT5B regulates IgM secretion in Waldenström's macroglobulinemia

Hodge, L. S., Ziesmer, S. C., Yang, Z. Z., Secreto, F. J., Novak, A. J. & Ansell, S. M., Feb 13 2014, In : Blood. 123, 7, p. 1055-1058 4 p.

Research output: Contribution to journalArticle

Waldenstrom Macroglobulinemia
Immunoglobulin M
Chemical activation
Cells
Janus Kinases
17 Citations (Scopus)

CXCR5 polymorphisms in non-Hodgkin lymphoma risk and prognosis

Charbonneau, B., Wang, A. H., Maurer, M. J., Asmann, Y., Zent, C. S., Link, B. K., Ansell, S. M., Weiner, G. J., Ozsan, N., Feldman, A. L., Witzig, T. E., Cunningham, J. M., Dogan, A., Habermann, T. M., Slager, S. L., Novak, A. J. & Cerhan, J. R., Sep 2013, In : Cancer Immunology, Immunotherapy. 62, 9, p. 1475-1484 10 p.

Research output: Contribution to journalArticle

Follicular Lymphoma
Non-Hodgkin's Lymphoma
Peripheral T-Cell Lymphoma
Mantle-Cell Lymphoma
Lymphoma, Large B-Cell, Diffuse
15 Citations (Scopus)

Cytokine gene polymorphisms and progression-free survival in classical Hodgkin lymphoma by EBV status: Results from two independent cohorts

Ghesquières, H., Maurer, M. J., Casasnovas, O., Ansell, S. M., Larrabee, B. R., Lech-Maranda, E., Novak, A. J., Borrel, A. L., Slager, S. L., Brice, P., Allmer, C., Brion, A., Ziesmer, S. C., Morschhauser, F., Habermann, T. M., Gaillard, I., Link, B. K., Stamatoullas, A., Fermé, C., Dogan, A. & 4 others, Macon, W. R., Audouin, J., Cerhan, J. R. & Salles, G., Nov 2013, In : Cytokine. 64, 2, p. 523-531 9 p.

Research output: Contribution to journalArticle

Polymorphism
Human Herpesvirus 4
Hodgkin Disease
Disease-Free Survival
Nucleotides
47 Citations (Scopus)
Waldenstrom Macroglobulinemia
Guidelines
Stem Cell Transplantation
Therapeutics
Clinical Trials
589 Citations (Scopus)

Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing

Lohr, J. G., Stojanov, P., Lawrence, M. S., Auclair, D., Chapuy, B., Sougnez, C., Cruz-Gordillo, P., Knoechel, B., Asmann, Y., Slager, S. L., Novak, A. J., Dogan, A., Ansell, S. M., Link, B. K., Zou, L., Gould, J., Saksena, G., Stransky, N., Rangel-Escareño, C., Fernandez-Lopez, J. C. & 14 others, Hidalgo-Miranda, A., Melendez-Zajgla, J., Hernández-Lemus, E., Schwarz-Cruz y Celis, A., Imaz-Rosshandler, I., Ojesina, A. I., Jung, J., Pedamallu, C. S., Lander, E. S., Habermann, T. M., Cerhan, J. R., Shipp, M. A., Getz, G. & Golub, T. R., Mar 6 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 10, p. 3879-3884 6 p.

Research output: Contribution to journalArticle

Exome
Lymphoma, Large B-Cell, Diffuse
Mutation
Genes
Point Mutation
28 Citations (Scopus)
Chemokine CXCL10
Lymphoma, Large B-Cell, Diffuse
Recurrence
Serum
Disease-Free Survival
69 Citations (Scopus)

Elevated serum B-lymphocyte stimulator levels in patients with familial lymphoproliferative disorders

Novak, A. J., Grote, D. M., Ziesmer, S. C., Kline, M. P., Manske, M. K., Slager, S. L., Witzig, T. E., Shanafelt, T., Call, T. G., Kay, N. E., Jelinek, D. F., Cerhan, J. R., Gross, J. A., Harder, B., Dillon, S. R. & Ansell, S. M., Feb 20 2006, In : Journal of Clinical Oncology. 24, 6, p. 983-987 5 p.

Research output: Contribution to journalArticle

B-Cell Activating Factor
Lymphoproliferative Disorders
Serum
Immune System Diseases
B-Cell Chronic Lymphocytic Leukemia
22 Citations (Scopus)

Elevated serum levels of IL-2R, IL-1RA, and CXCL9 are associated with a poor prognosis in follicular lymphoma

Mir, M. A., Maurer, M. J., Ziesmer, S. C., Slager, S. L., Habermann, T. M., Macon, W. R., Link, B. K., Syrbu, S., Witzig, T. E., Friedberg, J. W., Press, O., LeBlanc, M., Cerhan, J. R., Novak, A. J. & Ansell, S. M., Feb 5 2015, In : Blood. 125, 6, p. 992-998 7 p.

Research output: Contribution to journalArticle

Follicular Lymphoma
Chemotherapy
Interleukin-1 Receptors
Cytokines
Oncology
29 Citations (Scopus)

Establishment and characterization of a novel Waldenström macroglobulinemia cell line, MWCL-1

Hodge, L. S., Novak, A. J., Grote, D. M., Braggio, E. D., Ketterling, R. P., Manske, M. K., Price Troska, T. L., Ziesmer, S. C., Fonseca, R., Witzig, T. E., Morice, W. G., Gertz, M. & Ansell, S. M., May 12 2011, In : Blood. 117, 19

Research output: Contribution to journalArticle

Waldenstrom Macroglobulinemia
Tumors
Cells
Cell Line
Tumor Cell Line
322 Citations (Scopus)

Expression of BCMA, TACI, and BAFF-R in multiple myeloma: A mechanism for growth and survival

Novak, A. J., Darce, J. R., Arendt, B. K., Harder, B., Henderson, K., Kindsvogel, W., Gross, J. A., Greipp, P. R. & Jelinek, D. F., Jan 15 2004, In : Blood. 103, 2, p. 689-694 6 p.

Research output: Contribution to journalArticle

B-Cell Maturation Antigen
B-Cell Activating Factor
Multiple Myeloma
Survival
Growth
177 Citations (Scopus)

Expression of BLyS and its receptors in B-cell non-Hodgkin lymphoma: Correlation with disease activity and patient outcome

Novak, A. J., Grote, D. M., Stenson, M., Ziesmer, S. C., Witzig, T. E., Habermann, T. M., Harder, B., Ristow, K. M., Bram, R. J., Jelinek, D. F., Gross, J. A. & Ansell, S. M., Oct 15 2004, In : Blood. 104, 8, p. 2247-2253 7 p.

Research output: Contribution to journalArticle

B-Cell Lymphoma
Non-Hodgkin's Lymphoma
Cells
Tumors
Transmembrane Activator and CAML Interactor Protein
18 Citations (Scopus)

Expression of LAG-3 defines exhaustion of intratumoral PD-1+ T cells and correlates with poor outcome in follicular lymphoma

Yang, Z. Z., Kim, H. J., Villasboas Bisneto, J. J. C. ., Chen, Y. P., Price-Troska, T. P., Jalali, S., Wilson, M., Novak, A. J. & Ansell, S. M., Sep 1 2017, In : Oncotarget. 8, 37, p. 61425-61439 15 p.

Research output: Contribution to journalArticle

Follicular Lymphoma
T-Lymphocytes
Cytokines
Population
T-Cell Lymphoma
56 Citations (Scopus)
Chemokine Receptors
B-Cell Chronic Lymphocytic Leukemia
Disease Progression
B-Lymphocytes
Lymph Nodes
6 Citations (Scopus)

FCGR2A and FCGR3A polymorphisms in classical hodgkin lymphoma by epstein-barr virus status

Ghesquières, H., Dogan, A., Link, B. K., Maurer, M. J., Cunningham, J. M., Novak, A. J., Larrabee, B. R., Slager, S. L., Allmer, C., Habermann, T. M., Ansell, S. M. & Cerhan, J. R., 2013, In : Leukemia and Lymphoma. 54, 11, p. 2571-2573 3 p.

Research output: Contribution to journalArticle

Viral Matrix Proteins
IgG Receptors
B-Cell Lymphoma
Human Herpesvirus 4
Hodgkin Disease
2 Citations (Scopus)

FCGR3A/2A polymorphisms and diffuse large B-cell lymphoma outcome treated with immunochemotherapy: A meta-analysis on 1134 patients from two prospective cohorts

Ghesquières, H., Larrabee, B. R., Haioun, C., Link, B. K., Verney, A., Slager, S. L., Ketterer, N., Ansell, S. M., Delarue, R., Maurer, M. J., Fitoussi, O., Habermann, T. M., Peyrade, F., Dogan, A., Molina, T. J., Novak, A. J., Tilly, H., Cerhan, J. R. & Salles, G., 2016, (Accepted/In press) In : Hematological Oncology.

Research output: Contribution to journalArticle

Lymphoma, Large B-Cell, Diffuse
Meta-Analysis
Disease-Free Survival
Single Nucleotide Polymorphism
Survival
27 Citations (Scopus)

Genetically predicted longer telomere length is associated with increased risk of B-cell lymphoma subtypes

Machiela, M. J., Lan, Q., Slager, S. L., Vermeulen, R. C. H., Teras, L. R., Camp, N. J., Cerhan, J. R., Spinelli, J. J., Wang, S. S., Nieters, A., Vijai, J., Yeager, M., Wang, Z., Ghesquières, H., McKay, J., Conde, L., de Bakker, P. I. W., Cox, D. G., Burdett, L., Monnereau, A. & 100 others, Flowers, C. R., De Roos, A. J., Brooks-Wilson, A. R., Giles, G. G., Melbye, M., Gu, J., Jackson, R. D., Kane, E., Purdue, M. P., Vajdic, C. M., Albanes, D., Kelly, R. S., Zucca, M., Bertrand, K. A., Zeleniuch-Jacquotte, A., Lawrence, C., Hutchinson, A., Zhi, D., Habermann, T. M., Link, B. K., Novak, A. J., Dogan, A., Asmann, Y., Liebow, M., Thompson, C. A., Ansell, S. M., Witzig, T. E., Tilly, H., Haioun, C., Molina, T. J., Hjalgrim, H., Glimelius, B., Adami, H. O., Roos, G., Bracci, P. M., Riby, J., Smith, M. T., Holly, E. A., Cozen, W., Hartge, P., Morton, L. M., Severson, R. K., Tinker, L. F., North, K. E., Becker, N., Benavente, Y., Boffetta, P., Brennan, P., Foretova, L., Maynadie, M., Staines, A., Lightfoot, T., Crouch, S., Smith, A., Roman, E., Ryan Diver, W., Offit, K., Zelenetz, A., Klein, R. J., Villano, D. J., Zheng, T., Zhang, Y., Holford, T. R., Turner, J., Southey, M. C., Clavel, J., Virtamo, J., Weinstein, S., Riboli, E., Vineis, P., Kaaks, R., Boeing, H., Tjønneland, A., Angelucci, E., Di Lollo, S., Rais, M., De Vivo, I., Giovannucci, E., Kraft, P., Huang, J., Ma, B., Ye, Y., Chiu, B. C. H., Liang, L., Park, J. H., Chung, C. C., Weisenburger, D. D., Fraumeni, J. F., Salles, G., Glenn, M., Cannon-Albright, L., Curtin, K., Wu, X., Smedby, K. E., de Sanjose, S., Skibola, C. F., Berndt, S. I., Birmann, B. M., Chanock, S. J. & Rothman, N., Apr 15 2016, In : Human Molecular Genetics. 25, 8, p. 1663-1676 14 p., ddw027.

Research output: Contribution to journalArticle

Telomere
B-Cell Lymphoma
Non-Hodgkin's Lymphoma
B-Cell Chronic Lymphocytic Leukemia
B-Lymphocytes
5 Citations (Scopus)

Genetic diversity of newly diagnosed follicular lymphoma

Asmann, Y., Maurer, M. J., Wang, C., Sarangi, V., Ansell, S. M., Feldman, A. L., Nowakowski, G. S., Manske, M., Price-Troska, T., Yang, Z. Z., Slager, S. L., Habermann, T. M., Cerhan, J. R. & Novak, A. J., Jan 1 2014, In : Blood Cancer Journal. 4, 10, e256.

Research output: Contribution to journalArticle

Neoplasm Proteins
Follicular Lymphoma
Mutation
1 Citation (Scopus)

Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes

Din, L., Sheikh, M., Kosaraju, N., Smedby, K. E., Bernatsky, S., Berndt, S. I., Skibola, C. F., Nieters, A., Wang, S., McKay, J. D., Cocco, P., Maynadié, M., Foretová, L., Staines, A., Mack, T. M., de Sanjosé, S., Vyse, T. J., Padyukov, L., Monnereau, A., Arslan, A. A. & 72 others, Moore, A., Brooks-Wilson, A. R., Novak, A. J., Glimelius, B., Birmann, B. M., Link, B. K., Stewart, C., Vajdic, C. M., Haioun, C., Magnani, C., Conti, D. V., Cox, D. G., Casabonne, D., Albanes, D., Kane, E., Roman, E., Muzi, G., Salles, G., Giles, G. G., Adami, H. O., Ghesquières, H., De Vivo, I., Clavel, J., Cerhan, J. R., Spinelli, J. J., Hofmann, J., Vijai, J., Curtin, K., Costenbader, K. H., Onel, K., Offit, K., Teras, L. R., Morton, L., Conde, L., Miligi, L., Melbye, M., Ennas, M. G., Liebow, M., Purdue, M. P., Glenn, M., Southey, M. C., Din, M., Rothman, N., Camp, N. J., Wong Doo, N., Becker, N., Pradhan, N., Bracci, P. M., Boffetta, P., Vineis, P., Brennan, P., Kraft, P., Lan, Q., Severson, R. K., Vermeulen, R. C. H., Milne, R. L., Kaaks, R., Travis, R. C., Weinstein, S. J., Chanock, S. J., Ansell, S. M., Slager, S. L., Zheng, T., Zhang, Y., Benavente, Y., Taub, Z., Madireddy, L., Gourraud, P. A., Oksenberg, J. R., Cozen, W., Hjalgrim, H. & Khankhanian, P., Oct 1 2019, In : Genetic epidemiology. 43, 7, p. 844-863 20 p.

Research output: Contribution to journalArticle

Non-Hodgkin's Lymphoma
Autoimmune Diseases
Genome-Wide Association Study
Meta-Analysis
Follicular Lymphoma
48 Citations (Scopus)

Genetic variation in B-cell-activating factor is associated with an increased risk of developing B-cell non-Hodgkin lymphoma

Novak, A. J., Slager, S. L., Fredericksen, Z. S., Wang, A. H., Manske, M. M., Ziesmer, S., Liebow, M., Macon, W. R., Dillon, S. R., Witzig, T. E., Cerhan, J. R. & Ansell, S. M., May 15 2009, In : Cancer Research. 69, 10, p. 4217-4224 8 p.

Research output: Contribution to journalArticle

B-Cell Activating Factor
B-Cell Lymphoma
Non-Hodgkin's Lymphoma
Lymphoma
Alleles
60 Citations (Scopus)

Genetic variation in tumor necrosis factor and the nuclear factor-κB canonical pathway and risk of non-Hodgkin's lymphoma

Cerhan, J. R., Liu-Mares, W., Fredericksen, Z. S., Novak, A. J., Cunningham, J. M., Kay, N. E., Dogan, A., Liebow, M., Wang, A. H., Call, T. G., Habermann, T. M., Ansell, S. M. & Slager, S. L., Nov 2008, In : Cancer Epidemiology Biomarkers and Prevention. 17, 11, p. 3161-3169 9 p.

Research output: Contribution to journalArticle

Non-Hodgkin's Lymphoma
Tumor Necrosis Factor-alpha
Single Nucleotide Polymorphism
Genes
Odds Ratio
57 Citations (Scopus)

Genome-wide association study identifies five susceptibility loci for follicular lymphoma outside the HLA region

Skibola, C. F., Berndt, S. I., Vijai, J., Conde, L., Wang, Z., Yeager, M., De Bakker, P. I. W., Birmann, B. M., Vajdic, C. M., Foo, J. N., Bracci, P. M., Vermeulen, R. C. H., Slager, S. L., De Sanjose, S., Wang, S. S., Linet, M. S., Salles, G., Lan, Q., Severi, G., Hjalgrim, H. & 92 others, Lightfoot, T., Melbye, M., Gu, J., Ghesquières, H., Link, B. K., Morton, L. M., Holly, E. A., Smith, A., Tinker, L. F., Teras, L. R., Kricker, A., Becker, N., Purdue, M. P., Spinelli, J. J., Zhang, Y., Giles, G. G., Vineis, P., Monnereau, A., Bertrand, K. A., Albanes, D., Zeleniuch-Jacquotte, A., Gabbas, A., Chung, C. C., Burdett, L., Hutchinson, A., Lawrence, C., Montalvan, R., Liang, L., Huang, J., Ma, B., Liu, J., Adami, H. O., Glimelius, B., Ye, Y., Nowakowski, G. S., Dogan, A., Thompson, C. A., Habermann, T. M., Novak, A. J., Liebow, M., Witzig, T. E., Weiner, G. J., Schenk, M., Hartge, P., De Roos, A. J., Cozen, W., Zhi, D., Akers, N. K., Riby, J., Smith, M. T., Lacher, M., Villano, D. J., Maria, A., Roman, E., Kane, E., Jackson, R. D., North, K. E., Diver, W. R., Turner, J., Armstrong, B. K., Benavente, Y., Boffetta, P., Brennan, P., Foretova, L., Maynadie, M., Staines, A., McKay, J., Brooks-Wilson, A. R., Zheng, T., Holford, T. R., Chamosa, S., Kaaks, R., Kelly, R. S., Ohlsson, B., Travis, R. C., Weiderpass, E., Clavel, J., Giovannucci, E., Kraft, P., Virtamo, J., Mazza, P., Cocco, P., Ennas, M. G., Chiu, B. C. H., Fraumeni, J. F., Nieters, A., Offit, K., Wu, X., Cerhan, J. R., Smedby, K. E., Chanock, S. J. & Rothman, N., 2014, In : American Journal of Human Genetics. 95, 4, p. 462-471 10 p.

Research output: Contribution to journalArticle

Follicular Lymphoma
Genome-Wide Association Study
HLA Antigens
Alleles
Odds Ratio
119 Citations (Scopus)

Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia

Berndt, S. I., Skibola, C. F., Joseph, V., Camp, N. J., Nieters, A., Wang, Z., Cozen, W., Monnereau, A., Wang, S. S., Kelly, R. S., Lan, Q., Teras, L. R., Chatterjee, N., Chung, C. C., Yeager, M., Brooks-Wilson, A. R., Hartge, P., Purdue, M. P., Birmann, B. M., Armstrong, B. K. & 110 others, Cocco, P., Zhang, Y., Severi, G., Zeleniuch-Jacquotte, A., Lawrence, C., Burdette, L., Yuenger, J., Hutchinson, A., Jacobs, K. B., Call, T. G., Shanafelt, T. D., Novak, A. J., Kay, N. E., Liebow, M., Wang, A. H., Smedby, K. E., Adami, H. O., Melbye, M., Glimelius, B., Chang, E. T., Glenn, M., Curtin, K., Cannon-Albright, L. A., Jones, B., Diver, W. R., Link, B. K., Weiner, G. J., Conde, L., Bracci, P. M., Riby, J., Holly, E. A., Smith, M. T., Jackson, R. D., Tinker, L. F., Benavente, Y., Becker, N., Boffetta, P., Brennan, P., Foretova, L., Maynadie, M., McKay, J., Staines, A., Rabe, K. G., Achenbach, S. J., Vachon, C. M., Goldin, L. R., Strom, S. S., Lanasa, M. C., Spector, L. G., Leis, J. F., Cunningham, J. M., Weinberg, J. B., Morrison, V. A., Caporaso, N. E., Norman, A. D., Linet, M. S., De Roos, A. J., Morton, L. M., Severson, R. K., Riboli, E., Vineis, P., Kaaks, R., Trichopoulos, D., Masala, G., Weiderpass, E., Chirlaque, M. D., Vermeulen, R. C. H., Travis, R. C., Giles, G. G., Albanes, D., Virtamo, J., Weinstein, S., Clavel, J., Zheng, T., Holford, T. R., Offit, K., Zelenetz, A., Klein, R. J., Spinelli, J. J., Bertrand, K. A., Laden, F., Giovannucci, E., Kraft, P., Kricker, A., Turner, J., Vajdic, C. M., Ennas, M. G., Ferri, G. M., Miligi, L., Liang, L., Sampson, J., Crouch, S., Park, J. H., North, K. E., Cox, A., Snowden, J. A., Wright, J., Carracedo, A., Lopez-Otin, C., Bea, S., Salaverria, I., Martin-Garcia, D., Campo, E., Fraumeni, J. F., De Sanjose, S., Hjalgrim, H., Cerhan, J. R., Chanock, S. J., Rothman, N. & Slager, S. L., Aug 2013, In : Nature Genetics. 45, 8, p. 868-876 9 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
B-Cell Chronic Lymphocytic Leukemia
Meta-Analysis
Single Nucleotide Polymorphism
Genome
11 Citations (Scopus)

Genome-Wide association study of event-free survival in diffuse large B-cell lymphoma treated with immunochemotherapy

Ghesquieres, H., Slager, S. L., Jardin, F., Veron, A. S., Asmann, Y., Maurer, M. J., Fest, T., Habermann, T. M., Bene, M. C., Novak, A. J., Mareschal, S., Haioun, C., Lamy, T., Ansell, S. M., Tilly, H., Witzig, T. E., Weiner, G. J., Feldman, A. L., Dogan, A., Cunningham, J. M. & 7 others, Olswold, C. L., Molina, T. J., Link, B. K., Milpied, N., Cox, D. G., Salles, G. A. & Cerhan, J. R., Nov 20 2015, In : Journal of Clinical Oncology. 33, 33, p. 3930-3937 8 p.

Research output: Contribution to journalArticle

Lymphoma, Large B-Cell, Diffuse
Genome-Wide Association Study
Disease-Free Survival
Single Nucleotide Polymorphism
Survival
28 Citations (Scopus)

Germline variation in apoptosis pathway genes and risk of non-Hodgkin's lymphoma

Kelly, J. L., Novak, A. J., Fredericksen, Z. S., Liebow, M., Ansell, S. M., Dogan, A., Wang, A. H., Witzig, T. E., Call, T. G., Kay, N. E., Habermann, T. M., Slager, S. L. & Cerhan, J. R., Nov 2010, In : Cancer Epidemiology Biomarkers and Prevention. 19, 11, p. 2847-2858 12 p.

Research output: Contribution to journalArticle

Non-Hodgkin's Lymphoma
Apoptosis
Single Nucleotide Polymorphism
Genes
Genetic Translocation
23 Citations (Scopus)

Germline variation in complement genes and event-free survival in follicular and diffuse large B-cell lymphoma

Charbonneau, B., Maurer, M. J., Fredericksen, Z. S., Zent, C. S., Link, B. K., Novak, A. J., Ansell, S. M., Weiner, G. J., Wang, A. H., Witzig, T. E., Dogan, A., Slager, S. L., Habermann, T. M. & Cerhan, J. R., Sep 2012, In : American Journal of Hematology. 87, 9, p. 880-885 6 p.

Research output: Contribution to journalArticle

Follicular Lymphoma
Lymphoma, Large B-Cell, Diffuse
Disease-Free Survival
Genes
Innate Immunity
27 Citations (Scopus)

GLI2 transcription factor mediates cytokine cross-talk in the tumor microenvironment

Elsawa, S. F., Almada, L. L., Ziesmer, S. C., Novak, A. J., Witzig, T. E., Ansell, S. M. & Fernandez-Zapico, M. E., Jun 17 2011, In : Journal of Biological Chemistry. 286, 24, p. 21524-21534 11 p.

Research output: Contribution to journalArticle

Tumor Microenvironment
Tumors
Transcription Factors
Cells
Cytokines