• 10071 Citations
  • 56 Scopus h-Index
19962020

Research output per year

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Research Output

2020

Marked Up-Regulation of ACE2 in Hearts of Patients With Obstructive Hypertrophic Cardiomyopathy: Implications for SARS-CoV-2–Mediated COVID-19

Bos, J. M., Hebl, V. B., Oberg, A. L., Sun, Z., Herman, D. S., Teekakirikul, P., Seidman, J. G., Seidman, C. E., dos Remedios, C. G., Maleszewski, J., Schaff, H. V., Dearani, J., Noseworthy, P., Friedman, P. A., Ommen, S. R., Brozovich, F. V. & Ackerman, M. J., Jan 1 2020, (Accepted/In press) In : Mayo Clinic proceedings.

Research output: Contribution to journalArticle

Open Access
2019

53BP1 as a potential predictor of response in PARP inhibitor-treated homologous recombination-deficient ovarian cancer

Hurley, R. M., Wahner Hendrickson, A. E., Visscher, D. W., Ansell, P., Harrell, M. I., Wagner, J. M., Negron, V., Goergen, K. M., Maurer, M. J., Oberg, A. L., Meng, X. W., Flatten, K. S., De Jonge, M. J. A., Van Herpen, C. D., Gietema, J. A., Koornstra, R. H. T., Jager, A., den Hollander, M. W., Dudley, M., Shepherd, S. P. & 2 others, Swisher, E. M. & Kaufmann, S. H., Apr 2019, In : Gynecologic oncology. 153, 1, p. 127-134 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Agnostic Pathway/Gene Set Analysis of Genome-Wide Association Data Identifies Associations for Pancreatic Cancer

Walsh, N., Zhang, H., Hyland, P. L., Yang, Q., Mocci, E., Zhang, M., Childs, E. J., Collins, I., Wang, Z., Arslan, A. A., Beane-Freeman, L., Bracci, P. M., Brennan, P., Canzian, F., Duell, E. J., Gallinger, S., Giles, G. G., Goggins, M., Goodman, G. E., Goodman, P. J. & 78 others, Hung, R. J., Kooperberg, C., Kurtz, R. C., Malats, N., Lemarchand, L., Neale, R. E., Olson, S. H., Scelo, G., Shu, X. O., Van Den Eeden, S. K., Visvanathan, K., White, E., Zheng, W., Albanes, D., Andreotti, G., Babic, A., Bamlet, W. R., Berndt, S. I., Borgida, A., Boutron-Ruault, M. C., Brais, L., Bueno-De-Mesquita, B., Buring, J., Chaffee, K. G., Chanock, S., Cleary, S., Cotterchio, M., Foretova, L., Fuchs, C., M Gaziano, J. M., Giovannucci, E., Hackert, T., Haiman, C., Hartge, P., Hasan, M., Helzlsouer, K. J., Herman, J., Holcatova, I., Holly, E. A., Hoover, R., Janout, V., Klein, E. A., Laheru, D., Lee, I. M., Lu, L., Mannisto, S., Milne, R. L., Oberg, A. L., Orlow, I., Patel, A. V., Peters, U., Porta, M., Real, F. X., Rothman, N., Sesso, H. D., Severi, G., Silverman, D., Strobel, O., Sund, M., Thornquist, M. D., Tobias, G. S., Wactawski-Wende, J., Wareham, N., Weiderpass, E., Wentzensen, N., Wheeler, W., Yu, H., Zeleniuch-Jacquotte, A., Kraft, P., Li, D., Jacobs, E. J., Petersen, G. M., Wolpin, B. M., Risch, H. A., Amundadottir, L. T., Yu, K., Klein, A. P. & Stolzenberg-Solomon, R. Z., Jun 1 2019, In : Journal of the National Cancer Institute. 111, 6, p. 557-567 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Analysis of heritability and genetic architecture of pancreatic cancer: A PANC4 study

Chen, F., Childs, E. J., Mocci, E., Bracci, P., Gallinger, S., Li, D., Neale, R. E., Olson, S. H., Scelo, G., Bamlet, W. R., Blackford, A. L., Borges, M., Brennan, P., Chaffee, K. G., Duggal, P., Hassan, M. J., Holly, E. A., Hung, R. J., Goggins, M. G., Kurtz, R. C. & 6 others, Oberg, A. L., Orlow, I., Yu, H., Petersen, G. M., Risch, H. A. & Klein, A. P., Jan 1 2019, In : Cancer Epidemiology Biomarkers and Prevention. 28, 7, p. 1238-1245 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

BRCA1 deficiency upregulates NNMT, which reprograms metabolism and sensitizes ovarian cancer cells to mitochondrial metabolic targeting agents

Kanakkanthara, A., Kurmi, K., Ekstrom, T. L., Hou, X., Purfeerst, E. R., Heinzen, E. P., Correia, C., Huntoon, C. J., O'Brien, D., Wahner Hendrickson, A. E., Dowdy, S. C., Li, H., Oberg, A. L., Hitosugi, T., Kaufmann, S. H., Weroha, S. J. & Karnitz, L. M., Dec 1 2019, In : Cancer research. 79, 23, p. 5920-5929 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Genes associated with bowel metastases in ovarian cancer

Mariani, A., Wang, C., Oberg, A. L., Riska, S. M., Torres, M., Kumka, J., Multinu, F., Sagar, G., Roy, D., Jung, DB. B., Zhang, Q., Grassi, T., Visscher, D. W., Patel, V. P., Jin, L., Staub, J. K., Cliby, W. A., Weroha, S. J., Kalli, K. R., Hartmann, L. C. & 3 others, Kaufmann, S. H., Goode, E. L. & Shridhar, V., Jan 1 2019, In : Gynecologic oncology.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Overcoming platinum resistance in ovarian cancer by targeting pregnancy-associated plasma protein-A

Torres, D., Hou, X., Bale, L., Heinzen, E. P., Maurer, M. J., Zanfagnin, V., Oberg, A. L., Conover, C. & Weroha, S. J., Jan 1 2019, In : PloS one. 14, 11, e0224564.

Research output: Contribution to journalArticle

Open Access

Poly(adenosine diphosphate ribose) polymerase inhibitors induce autophagy-mediated drug resistance in ovarian cancer cells, xenografts, and patient-derived xenograft models

Santiago-O'Farrill, J. M., Weroha, S. J., Hou, X., Oberg, A. L., Heinzen, E. P., Maurer, M. J., Pang, L., Rask, P., Amaravadi, R. K., Becker, S. E., Romero, I., Rubio, M. J., Matias-Guiu, X., Santacana, M., Llombart-Cussac, A., Poveda, A., Lu, Z. & Bast, R. C., Jan 1 2019, (Accepted/In press) In : Cancer.

Research output: Contribution to journalArticle

1 Scopus citations

Risk of Different Cancers Among First-degree Relatives of Pancreatic Cancer Patients: Influence of Probands' Susceptibility Gene Mutation Status

Antwi, S., Fagan, S. E., Chaffee, K. G., Bamlet, W. R., Hu, C., Polley, E., Hart, S., Shimelis, H., Lilyquist, J., Gnanaolivu, R. D., Mc Williams, R. R., Oberg, A. L., Couch, F. J. & Petersen, G. M., Mar 1 2019, In : Journal of the National Cancer Institute. 111, 3, p. 264-271 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Serum Proteomics on the Basis of Discovery of Predictive Biomarkers of Response to Androgen Deprivation Therapy in Advanced Prostate Cancer

Kohli, M., Oberg, A. L., Mahoney, D. W., Riska, S. M., Sherwood, R., Zhang, Y., Zenka, R. M., Sahasrabudhe, D., Qin, R. & Zhang, S., Aug 2019, In : Clinical Genitourinary Cancer. 17, 4, p. 248-253.e7

Research output: Contribution to journalArticle

1 Scopus citations

ZC3H18 specifically binds and activates the BRCA1 promoter to facilitate homologous recombination in ovarian cancer

Kanakkanthara, A., Huntoon, C. J., Hou, X., Zhang, M., Heinzen, E. P., O’Brien, D. R., Oberg, A. L., John Weroha, S., Kaufmann, S. H. & Karnitz, L. M., Dec 1 2019, In : Nature communications. 10, 1, 4632.

Research output: Contribution to journalArticle

Open Access
2018

Colonoscopy surveillance for high risk polyps does not always prevent colorectal cancer

Mouchli, M. A., Ouk, L., Scheitel, M. R., Chaudhry, A. P., Felmlee-Devine, D., Grill, D. E., Rashtak, S., Wang, P., Wang, J., Chaudhry, R., Smyrk, T. C., Oberg, A. L., Druliner, B. R. & Boardman, L. A., Feb 28 2018, In : World Journal of Gastroenterology. 24, 8, p. 905-916 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

Constitutive Interferon Pathway Activation in Tumors as an Efficacy Determinant Following Oncolytic Virotherapy

Kurokawa, C., Iankov, I. D., Anderson, S. K., Aderca, I., Leontovich, A. A., Maurer, M. J., Oberg, A. L., Schroeder, M. A., Giannini, C., Greiner, S. M., Becker, M. A., Thompson, E. A., Haluska, P. R. J., Jentoft, M. E., Parney, I. F., Weroha, S. J., Jen, J., Sarkaria, J. N. & Galanis, E., Oct 1 2018, In : Journal of the National Cancer Institute. 110, 10, p. 1123-1132 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer

Klein, A. P., Wolpin, B. M., Risch, H. A., Stolzenberg-Solomon, R. Z., Mocci, E., Zhang, M., Canzian, F., Childs, E. J., Hoskins, J. W., Jermusyk, A., Zhong, J., Chen, F., Albanes, D., Andreotti, G., Arslan, A. A., Babic, A., Bamlet, W. R., Beane-Freeman, L., Berndt, S. I., Blackford, A. & 103 others, Borges, M., Borgida, A., Bracci, P. M., Brais, L., Brennan, P., Brenner, H., Bueno-De-Mesquita, B., Buring, J., Campa, D., Capurso, G., Cavestro, G. M., Chaffee, K. G., Chung, C. C., Cleary, S., Cotterchio, M., Dijk, F., Duell, E. J., Foretova, L., Fuchs, C., Funel, N., Gallinger, S., Gaziano, J. M. M., Gazouli, M., Giles, G. G., Giovannucci, E., Goggins, M., Goodman, G. E., Goodman, P. J., Hackert, T., Haiman, C., Hartge, P., Hasan, M., Hegyi, P., Helzlsouer, K. J., Herman, J., Holcatova, I., Holly, E. A., Hoover, R., Hung, R. J., Jacobs, E. J., Jamroziak, K., Janout, V., Kaaks, R., Khaw, K. T., Klein, E. A., Kogevinas, M., Kooperberg, C., Kulke, M. H., Kupcinskas, J., Kurtz, R. J., Laheru, D., Landi, S., Lawlor, R. T., Lee, I. M., Lemarchand, L., Lu, L., Malats, N., Mambrini, A., Mannisto, S., Milne, R. L., Mohelníková-Duchoňová, B., Neale, R. E., Neoptolemos, J. P., Oberg, A. L., Olson, S. H., Orlow, I., Pasquali, C., Patel, A. V., Peters, U., Pezzilli, R., Porta, M., Real, F. X., Rothman, N., Scelo, G., Sesso, H. D., Severi, G., Shu, X. O., Silverman, D., Smith, J. P., Soucek, P., Sund, M., Talar-Wojnarowska, R., Tavano, F., Thornquist, M. D., Tobias, G. S., Van Den Eeden, S. K., Vashist, Y., Visvanathan, K., Vodicka, P., Wactawski-Wende, J., Wang, Z., Wentzensen, N., White, E., Yu, H., Yu, K., Zeleniuch-Jacquotte, A., Zheng, W., Kraft, P., Li, D., Chanock, S., Obazee, O., Petersen, G. M. & Amundadottir, L. T., Dec 1 2018, In : Nature communications. 9, 1, 556.

Research output: Contribution to journalArticle

32 Scopus citations

Molecular characterization of colorectal adenomas with and without malignancy reveals distinguishing genome, transcriptome and methylome alterations

Druliner, B. R., Wang, P., Bae, T., Baheti, S., Slettedahl, S., Mahoney, D., Vasmatzis, N., Xu, H., Kim, M., Bockol, M., O'Brien, D., Grill, D., Warner, N., Munoz-Gomez, M., Kossick, K., Johnson, R., Mouchli, M., Felmlee-Devine, D., Washechek-Aletto, J., Smyrk, T. C. & 6 others, Oberg, A. L., Wang, J., Chia, N. D., Abyzov, A., Ahlquist, D. & Boardman, L. A., Dec 1 2018, In : Scientific Reports. 8, 1, 3161.

Research output: Contribution to journalArticle

6 Scopus citations

Pancreatic cancer risk is modulated by inflammatory potential of diet and ABO genotype: A consortia-based evaluation and replication study

Antwi, S. O., Bamlet, W. R., Pedersen, K. S., Chaffee, K. G., Risch, H. A., Shivappa, N., Steck, S. E., Anderson, K. E., Bracci, P. M., Polesel, J., Serraino, D., La Vecchia, C., Bosetti, C., Li, D., Oberg, A. L., Arslan, A. A., Albanes, D., Duell, E. J., Huybrechts, I., Amundadottir, L. T. & 16 others, Hoover, R., Mannisto, S., Chanock, S. J., Zheng, W., Shu, X. O., Stepien, M., Canzian, F., Bueno-De-Mesquita, B., Quirós, J. R., Zeleniuch-Jacquotte, A., Bruinsma, F., Milne, R. L., Giles, G. G., Hébert, J. R., Stolzenberg-Solomon, R. Z. & Petersen, G. M., Jul 30 2018, In : Carcinogenesis. 39, 8, p. 1056-1067 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Prevalence of germ-line mutations in cancer genes among pancreatic cancer patients with a positive family history

Chaffee, K. G., Oberg, A. L., Mc Williams, R. R., Majithia, N., Allen, B. A., Kidd, J., Singh, N., Hartman, A. R., Wenstrup, R. J. & Petersen, G. M., Jan 1 2018, In : Genetics in Medicine. 20, 1, p. 119-127 9 p.

Research output: Contribution to journalArticle

25 Scopus citations
2017

Association between alcohol consumption, folate intake, and risk of pancreatic cancer: A case-control study

Yallew, W., Bamlet, W. R., Oberg, A. L., Anderson, K. E., Olson, J. E., Sinha, R., Petersen, G. M., Stolzenberg-Solomon, R. Z. & Jansen, R. J., May 1 2017, In : Nutrients. 9, 5, 448.

Research output: Contribution to journalArticle

3 Scopus citations

Bevacizumab may differentially improve ovarian cancer outcome in patients with proliferative and mesenchymal molecular subtypes

Kommoss, S., Winterhoff, B., Oberg, A. L., Konecny, G. E., Wang, C., Riska, S. M., Fan, J. B., Maurer, M. J., April, C., Shridhar, V., Kommoss, F., Du Bois, A., Hilpert, F., Mahner, S., Baumann, K., Schroeder, W., Burges, A., Canzler, U., Chien, J., Embleton, A. C. & 7 others, Parmar, M., Kaplan, R., Perren, T., Hartmann, L. C., Goode, E. L., Dowdy, S. C. & Pfisterer, J., Jul 15 2017, In : Clinical Cancer Research. 23, 14, p. 3794-3801 8 p.

Research output: Contribution to journalArticle

27 Scopus citations

Cellular senescence mediates fibrotic pulmonary disease

Schafer, M. J., White, T. A., Iijima, K., Haak, A. J., Ligresti, G., Atkinson, E. J., Oberg, A. L., Birch, J., Salmonowicz, H., Zhu, Y., Mazula, D. L., Brooks, R. W., Fuhrmann-Stroissnigg, H., Pirtskhalava, T., Prakash, Y. S., Tchkonia, T., Robbins, P. D., Aubry, M. C., Passos, J. F., Kirkland, J. L. & 3 others, Tschumperlin, D. J., Kita, H. & LeBrasseur, N. K., Feb 23 2017, In : Nature communications. 8, 14532.

Research output: Contribution to journalArticle

297 Scopus citations

Combination epigenetic therapy in metastatic colorectal cancer (mCRC) with subcutaneous 5-azacitidine and entinostat; a phase 2 consortium/stand Up 2 cancer study

Azad, N. S., El-Khoueiry, A., Yin, J., Oberg, A. L., Flynn, P., Adkins, D., Sharma, A., Weisenberger, D. J., Brown, T., Medvari, P., Jones, P. A., Easwaran, H., Kamel, I., Bahary, N., Kim, G., Picus, J., Pitot, H. C., Erlichman, C., Donehower, R., Shen, H. & 4 others, Laird, P. W., Piekarz, R., Baylin, S. & Ahuja, N., Jan 1 2017, In : Oncotarget. 8, 21, p. 35326-35338 13 p.

Research output: Contribution to journalArticle

25 Scopus citations

Detection of early pancreatic ductal adenocarcinoma with thrombospondin-2 & CA19-9 blood markers

Kim, J., Bamlet, W. R., Oberg, A. L., Chaffee, K. G., Donahue, G., Cao, X. J., Chari, S. T., Garcia, B. A., Petersen, G. M. & Zaret, K. S., Jul 12 2017, In : Science Translational Medicine. 9, 398, eaah5583.

Research output: Contribution to journalArticle

59 Scopus citations

EGFR as a prognostic biomarker and therapeutic target in ovarian cancer: Evaluation of patient cohort and literature review

Mehner, C., Oberg, A. L., Goergen, K. M., Kalli, K. R., Maurer, M. J., Nassar, A., Goode, E. L., Keeney, G., Jatoi, A., Radisky, D. C. & Radisky, E. S., May 1 2017, In : Genes and Cancer. 8, 5-6, p. 589-599 11 p.

Research output: Contribution to journalReview article

12 Scopus citations

Genetically predicted telomere length is not associated with pancreatic cancer risk

Antwi, S., Bamlet, W. R., Broderick, B. T., Chaffee, K. G., Oberg, A. L., Jatoi, A., Boardman, L. A. & Petersen, G. M., Jun 1 2017, In : Cancer Epidemiology Biomarkers and Prevention. 26, 6, p. 971-974 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma

Raphael, B. J., Hruban, R. H., Aguirre, A. J., Moffitt, R. A., Yeh, J. J., Stewart, C., Robertson, A. G., Cherniack, A. D., Gupta, M., Getz, G., Gabriel, S. B., Meyerson, M., Cibulskis, C., Fei, S. S., Hinoue, T., Shen, H., Laird, P. W., Ling, S., Lu, Y., Mills, G. B. & 251 others, Akbani, R., Loher, P., Londin, E. R., Rigoutsos, I., Telonis, A. G., Gibb, E. A., Goldenberg, A., Mezlini, A. M., Hoadley, K. A., Collisson, E., Lander, E., Murray, B. A., Hess, J., Rosenberg, M., Bergelson, L., Zhang, H., Cho, J., Tiao, G., Kim, J., Livitz, D., Leshchiner, I., Reardon, B., Van Allen, E., Kamburov, A., Beroukhim, R., Saksena, G., Schumacher, S. E., Noble, M. S., Heiman, D. I., Gehlenborg, N., Kim, J., Lawrence, M. S., Adsay, V., Petersen, G., Klimstra, D., Bardeesy, N., Leiserson, M. D. M., Bowlby, R., Kasaian, K., Birol, I., Mungall, K. L., Sadeghi, S., Weinstein, J. N., Spellman, P. T., Liu, Y., Amundadottir, L. T., Tepper, J., Singhi, A. D., Dhir, R., Paul, D., Smyrk, T., Zhang, L., Kim, P., Bowen, J., Frick, J., Gastier-Foster, J. M., Gerken, M., Lau, K., Leraas, K. M., Lichtenberg, T. M., Ramirez, N. C., Renkel, J., Sherman, M., Wise, L., Yena, P., Zmuda, E., Shih, J., Ally, A., Balasundaram, M., Carlsen, R., Chu, A., Chuah, E., Clarke, A., Dhalla, N., Holt, R. A., Jones, S. J. M., Lee, D., Ma, Y., Marra, M. A., Mayo, M., Moore, R. A., Mungall, A. J., Schein, J. E., Sipahimalani, P., Tam, A., Thiessen, N., Tse, K., Wong, T., Brooks, D., Auman, J. T., Balu, S., Bodenheimer, T., Hayes, D. N., Hoyle, A. P., Jefferys, S. R., Jones, C. D., Meng, S., Mieczkowski, P. A., Mose, L. E., Perou, C. M., Perou, A. H., Roach, J., Shi, Y., Simons, J. V., Skelly, T., Soloway, M. G., Tan, D., Veluvolu, U., Parker, J. S., Wilkerson, M. D., Korkut, A., Senbabaoglu, Y., Burch, P., McWilliams, R., Chaffee, K., Oberg, A., Zhang, W., Gingras, M. C., Wheeler, D. A., Xi, L., Albert, M., Bartlett, J., Sekhon, H., Stephen, Y., Howard, Z., Judy, M., Breggia, A., Shroff, R. T., Chudamani, S., Liu, J., Lolla, L., Naresh, R., Pihl, T., Sun, Q., Wan, Y., Wu, Y., Jennifer, S., Roggin, K., Becker, K. F., Behera, M., Bennett, J., Boice, L., Burks, E., Carlotti Junior, C. G., Chabot, J., Pretti da Cunha Tirapelli, D., Sebastião dos Santos, J., Dubina, M., Eschbacher, J., Huang, M., Huelsenbeck-Dill, L., Jenkins, R., Karpov, A., Kemp, R., Lyadov, V., Maithel, S., Manikhas, G., Montgomery, E., Noushmehr, H., Osunkoya, A., Owonikoko, T., Paklina, O., Potapova, O., Ramalingam, S., Rathmell, W. K., Rieger-Christ, K., Saller, C., Setdikova, G., Shabunin, A., Sica, G., Su, T., Sullivan, T., Swanson, P., Tarvin, K., Tavobilov, M., Thorne, L. B., Urbanski, S., Voronina, O., Wang, T., Crain, D., Curley, E., Gardner, J., Mallery, D., Morris, S., Paulauskis, J., Penny, R., Shelton, C., Shelton, T., Janssen, K. P., Bathe, O., Bahary, N., Slotta-Huspenina, J., Johns, A., Hibshoosh, H., Hwang, R. F., Sepulveda, A., Radenbaugh, A., Baylin, S. B., Berrios, M., Bootwalla, M. S., Holbrook, A., Lai, P. H., Maglinte, D. T., Mahurkar, S., Triche, T. J., Van Den Berg, D. J., Weisenberger, D. J., Chin, L., Kucherlapati, R., Kucherlapati, M., Pantazi, A., Park, P., Saksena, G., Voet, D., Lin, P., Frazer, S., Defreitas, T., Meier, S., Chin, L., Kwon, S. Y., Kim, Y. H., Park, S. J., Han, S. S., Kim, S. H., Kim, H., Furth, E., Tempero, M., Sander, C., Biankin, A., Chang, D., Bailey, P., Gill, A., Kench, J., Grimmond, S., Johns, A., Cancer Genome Initiative (APGI, A. P., Postier, R., Zuna, R., Sicotte, H., Demchok, J. A., Ferguson, M. L., Hutter, C. M., Mills Shaw, K. R., Sheth, M., Sofia, H. J., Tarnuzzer, R., Wang, Z., Yang, L., Zhang, J. J., Felau, I. & Zenklusen, J. C., Aug 14 2017, In : Cancer cell. 32, 2, p. 185-203.e13

Research output: Contribution to journalArticle

310 Scopus citations

Integration of immune cell populations, mRNA-Seq, and CpG methylation to better predict humoral immunity to influenza vaccination: Dependence of mRNA-Seq/CpG methylation on immune cell populations

Zimmermann, M. T., Kennedy, R. B., Grill, D. E., Oberg, A. L., Goergen, K. M., Ovsyannikova, I. G., Haralambieva, I. H. & Poland, G. A., Apr 21 2017, In : Frontiers in Immunology. 8, APR, 445.

Research output: Contribution to journalArticle

7 Scopus citations

Multicohort analysis reveals baseline transcriptional predictors of influenza vaccination responses

Avey, S., Cheung, F., Fermin, D., Frelinger, J., Gaujoux, R., Gottardo, R., Khatri, P., Kleinstein, S. H., Kotliarov, Y., Meng, H., Sauteraud, R., Shen-Orr, S. S., Tsang, J. S., Vallania, F., Anguiano, E., Baisch, J., Baldwin, N., Belshe, R. B., Blevins, T. P., Chaussabel, D. & 25 others, Davis, M. M., Fikrig, E., Grill, D. E., Hafler, D. A., Henrich, E., Joshi, S. R., Kaech, S. M., Kennedy, R. B., Mohanty, S., Montgomery, R. R., Oberg, A. L., Obermoser, G., Ovsyannikova, I. G., Karolina Palucka, A., Pascual, V., Poland, G. A., Pulendran, B., Reinherz, E. L., Shaw, A. C., Siconolfi, B., Stuart, K. D., Tsang, S., Ueda, I., Wilson, J. & Zapata, H. J., Apr 25 2017, In : Science Immunology. 2, 14, eaal4656.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Pooled clustering of high-grade serous ovarian cancer gene expression leads to novel consensus subtypes associated with survival and surgical outcomes

Wang, C., Armasu, S. M., Kalli, K. R., Maurer, M. J., Heinzen, E. P., Keeney, G. L., Cliby, W. A., Oberg, A. L., Kaufmann, S. H. & Goode, E. L., Aug 1 2017, In : Clinical Cancer Research. 23, 15, p. 4077-4085 9 p.

Research output: Contribution to journalArticle

27 Scopus citations
2016

An interaction quantitative trait loci tool implicates epistatic functional variants in an apoptosis pathway in smallpox vaccine eQTL data

Lareau, C. A., White, B. C., Oberg, A. L., Kennedy, R. B., Poland, G. A. & McKinney, B. A., Jun 1 2016, In : Genes and Immunity. 17, 4, p. 244-250 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

APOBEC3G expression correlates with T-cell infiltration and improved clinical outcomes in high-grade serous ovarian carcinoma

Leonard, B., Starrett, G. J., Maurer, M. J., Oberg, A. L., Van Bockstal, M., Van Dorpe, J., De Wever, O., Helleman, J., Sieuwerts, A. M., Berns, E. M. J. J., Martens, J. W. M., Anderson, B. D., Brown, W. L., Kalli, K. R., Kaufmann, S. H. & Harris, R. S., Sep 15 2016, In : Clinical Cancer Research. 22, 18, p. 4746-4755 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

EUS-guided fine-needle injection of gemcitabine for locally advanced and metastatic pancreatic cancer

Levy, M. J., Alberts, S. R., Bamlet, W. R., Burch, P. A., Farnell, M. B., Gleeson, F. C., Haddock, M., Kendrick, M. L., Oberg, A. L., Petersen, G. M., Takahashi, N. & Chari, S. T., Jul 21 2016, (Accepted/In press) In : Gastrointestinal Endoscopy.

Research output: Contribution to journalArticle

17 Scopus citations

Gene signatures associated with adaptive humoral immunity following seasonal influenza A/H1N1 vaccination

Ovsyannikova, I. G., Salk, H. M., Kennedy, R. B., Haralambieva, I. H., Zimmermann, M. T., Grill, D. E., Oberg, A. L. & Poland, G. A., Dec 1 2016, In : Genes and Immunity. 17, 7, p. 371-379 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Gene signatures related to HAI response following influenza A/H1N1 vaccine in older individuals

Ovsyannikova, I. G., Oberg, A. L., Kennedy, R. B., Zimmermann, M. T., Haralambieva, I. H., Goergen, K. M., Grill, D. E. & Poland, G. A., May 1 2016, In : Heliyon. 2, 5, e00098.

Research output: Contribution to journalArticle

12 Scopus citations

Immunosenescence-related transcriptomic and immunologic changes in older individuals following influenza vaccination

Kennedy, R. B., Ovsyannikova, I. G., Haralambieva, I. H., Oberg, A. L., Zimmermann, M. T., Grill, D. E. & Poland, G. A., Nov 2 2016, In : Frontiers in Immunology. 7, NOV, 450.

Research output: Contribution to journalArticle

20 Scopus citations

Immunosuppressive CD14+HLA-DRlo/neg monocytes are elevated in pancreatic cancer and “primed” by tumor-derived exosomes

Javeed, N., Gustafson, M., Dutta, S. K., Lin, Y., Bamlet, W. R., Oberg, A. L., Petersen, G. M., Chari, S. T., Dietz, A. B. & Mukhopadhyay, D., Dec 23 2016, (Accepted/In press) In : OncoImmunology.

Research output: Contribution to journalArticle

17 Scopus citations

In vivo anti-tumor activity of the PARP inhibitor niraparib in homologous recombination deficient and proficient ovarian carcinoma

AlHilli, M. M., Becker, M. A., Weroha, S. J., Flatten, K. S., Hurley, R. M., Harrell, M. I., Oberg, A. L., Maurer, M. J., Hawthorne, K. M., Hou, X., Harrington, S. C., McKinstry, S., Meng, X. W., Wilcoxen, K. M., Kalli, K. R., Swisher, E. M., Kaufmann, S. H. & Haluska, P., Nov 1 2016, In : Gynecologic Oncology. 143, 2, p. 379-388 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

Metformin use and survival of patients with pancreatic cancer: A cautionary lesson

Chaiteerakij, R., Petersen, G. M., Bamlet, W. R., Chaffee, K. G., Zhen, D. B., Burch, P. A., Leof, E. R., Roberts, L. R. & Oberg, A. L., Jun 1 2016, In : Journal of Clinical Oncology. 34, 16, p. 1898-1904 7 p.

Research output: Contribution to journalArticle

41 Scopus citations

Optimizing Mass Spectrometry Analyses: A Tailored Review on the Utility of Design of Experiments

Hecht, E. S., Oberg, A. L. & Muddiman, D. C., May 1 2016, In : Journal of the American Society for Mass Spectrometry. 27, 5, p. 767-785 19 p.

Research output: Contribution to journalArticle

25 Scopus citations

Pancreatic cancer: Associations of inflammatory potential of diet, cigarette smoking and long-standing diabetes

Antwi, S., Oberg, A. L., Shivappa, N., Bamlet, W. R., Chaffee, K. G., Steck, S. E., Hébert, J. R. & Petersen, G. M., May 1 2016, In : Carcinogenesis. 37, 5, p. 481-490 10 p.

Research output: Contribution to journalArticle

36 Scopus citations

Recursive indirect-paths modularity (RIP-M) for detecting community structure in RNA-seq co-expression networks

Rahmani, B., Zimmermann, M. T., Grill, D. E., Kennedy, R. B., Oberg, A. L., White, B. C., Poland, G. A. & McKinney, B. A., May 9 2016, In : Frontiers in Genetics. 7, MAY, 80.

Research output: Contribution to journalArticle

7 Scopus citations

System-wide associations between DNA-methylation, gene expression, and humoral immune response to influenza vaccination

Zimmermann, M. T., Oberg, A. L., Grill, D. E., Ovsyannikova, I. G., Haralambieva, I. H., Kennedy, R. B. & Poland, G. A., Mar 31 2016, In : PLoS One. 11, 3, e0152034.

Research output: Contribution to journalArticle

20 Scopus citations

The composition of immune cells serves as a predictor of adaptive immunity in a cohort of 50- to 74-year-old adults

Kennedy, R. B., Simon, W. L., Gibson, M. J., Goergen, K. M., Grill, D. E., Oberg, A. L. & Poland, G. A., 2016, (Accepted/In press) In : Immunology.

Research output: Contribution to journalArticle

6 Scopus citations

The integration of epistasis network and functional interactions in a GWAS implicates RXR pathway genes in the immune response to smallpox vaccine

McKinney, B. A., Lareau, C., Oberg, A. L., Kennedy, R. B., Ovsyannikova, I. G. & Poland, G. A., Aug 1 2016, In : PLoS One. 11, 8, e0158016.

Research output: Contribution to journalArticle

3 Scopus citations

Three new pancreatic cancer susceptibility signals identified on chromosomes 1q32.1, 5p15.33 and 8q24.21

Zhang, M., Wang, Z., Obazee, O., Jia, J., Childs, E. J., Hoskins, J., Figlioli, G., Mocci, E., Collins, I., Chung, C. C., Hautman, C., Arslan, A. A., Beane-Freeman, L., Bracci, P. M., Buring, J., Duell, E. J., Gallinger, S., Giles, G. G., Goodman, G. E., Goodman, P. J. & 103 others, Kamineni, A., Kolonel, L. N., Kulke, M. H., Malats, N., Olson, S. H., Sesso, H. D., Visvanathan, K., White, E., Zheng, W., Abnet, C. C., Albanes, D., Andreotti, G., Brais, L., Bas Bueno-de-Mesquita, H., Basso, D., Berndt, S. I., Boutron-Ruault, M. C., Bijlsma, M. F., Brenner, H., Burdette, L., Campa, D., Caporaso, N. E., Capurso, G., Cavestro, G. M., Cotterchio, M., Costello, E., Elena, J., Boggi, U., Michael Gaziano, J., Gazouli, M., Giovannucci, E. L., Goggins, M., Gross, M., Haiman, C. A., Hassan, M., Helzlsouer, K. J., Hu, N., Hunter, D. J., Iskierka-Jazdzewska, E., Jenab, M., Kaaks, R., Key, T. J., Khaw, K. T., Klein, E. A., Kogevinas, M., Krogh, V., Kupcinskas, J., Kurtz, R. C., Landi, M. T., Landi, S., Marchand, L. L., Mambrini, A., Mannisto, S., Milne, R. L., Neale, R. E., Oberg, A. L., Panico, S., Patel, A. V., Peeters, P. H. M., Peters, U., Pezzilli, R., Porta, M., Purdue, M., Ramón Quiros, J., Riboli, E., Rothman, N., Scarpa, A., Scelo, G., Shu, X. O., Silverman, D. T., Soucek, P., Strobel, O., Sund, M., Malecka-Panas, E., Taylor, P. R., Tavano, F., Travis, R. C., Thornquist, M., Tjønneland, A., Tobias, G. S., Trichopoulos, D., Vashist, Y., Vodicka, P., Wactawski-Wende, J., Wentzensen, N., Yu, H., Yu, K., Zeleniuch-Jacquotte, A., Kooperberg, C., Risch, H. A., Jacobs, E. J., Li, D., Fuchs, C., Hoover, R., Hartge, P., Chanock, S. J., Petersen, G. M., Stolzenberg-Solomon, R. S., Wolpin, B. M., Kraft, P., Klein, A. P., Canzian, F. & Amundadottir, L. T., Jan 1 2016, In : Oncotarget. 7, 41, p. 66328-66343 16 p.

Research output: Contribution to journalArticle

34 Scopus citations

Time Lapse to Colorectal Cancer: Telomere Dynamics Define the Malignant Potential of Polyps

Druliner, B. R., Ruan, X., Johnson, R., Grill, D., O'Brien, D., Lai, T. P., Rashtak, S., Felmlee-Devine, D., Washechek-Aletto, J., Malykh, A., Smyrk, T. C., Oberg, A. L., Liu, H. D., Shay, J. W., Ahlquist, D. A. & Boardman, L. A., Sep 1 2016, In : Clinical and Translational Gastroenterology. 7, 9, e188.

Research output: Contribution to journalArticle

4 Scopus citations

Transcriptional signatures of influenza A/H1N1-specific IgG memory-like B cell response in older individuals

Haralambieva, I. H., Ovsyannikova, I. G., Kennedy, R. B., Zimmermann, M. T., Grill, D. E., Oberg, A. L. & Poland, G. A., Jul 25 2016, In : Vaccine. 34, 34, p. 3993-4002 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Whole transcriptome profiling identifies CD93 and other plasma cell survival factor genes associated with measles-specific antibody response after vaccination

Haralambieva, I. H., Zimmermann, M. T., Ovsyannikova, I. G., Grill, D. E., Oberg, A. L., Kennedy, R. B. & Poland, G. A., Aug 1 2016, In : PLoS One. 11, 8, e0160970.

Research output: Contribution to journalArticle

9 Scopus citations
2015

Analysis of heritability and shared heritability based on genome-wide association studies for thirteen cancer types

Sampson, J. N., Wheeler, W. A., Yeager, M., Panagiotou, O., Wang, Z., Berndt, S. I., Lan, Q., Abnet, C. C., Amundadottir, L. T., Figueroa, J. D., Landi, M. T., Mirabello, L., Savage, S. A., Taylor, P. R., De Vivo, I., McGlynn, K. A., Purdue, M. P., Rajaraman, P., Adami, H. O., Ahlbom, A. & 388 others, Albanes, D., Amary, M. F., An, S. J., Andersson, U., Andriole, G., Andrulis, I. L., Angelucci, E., Ansell, S. M., Arici, C., Armstrong, B. K., Arslan, A. A., Austin, M. A., Baris, D., Barkauskas, D. A., Bassig, B. A., Becker, N., Benavente, Y., Benhamou, S., Berg, C., Van Den Berg, D., Bernstein, L., Bertrand, K. A., Birmann, B. M., Black, A., Boeing, H., Boffetta, P., Boutron-Ruault, M. C., Bracci, P. M., Brinton, L., Brooks-Wilson, A. R., Bueno-De-Mesquita, H. B., Burdett, L., Buring, J., Butler, M. A., Cai, Q., Cancel-Tassin, G., Canzian, F., Carrato, A., Carreon, T., Carta, A., Chan, J. K. C., Chang, E. T., Chang, G. C., Chang, I. S., Chang, J., Chang-Claude, J., Chen, C. 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Research output: Contribution to journalArticle

70 Scopus citations

Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer

Childs, E. J., Mocci, E., Campa, D., Bracci, P. M., Gallinger, S., Goggins, M., Li, D., Neale, R. E., Olson, S. H., Scelo, G., Amundadottir, L. T., Bamlet, W. R., Bijlsma, M. F., Blackford, A., Borges, M., Brennan, P., Brenner, H., Bueno-De-Mesquita, H. B., Canzian, F., Capurso, G. & 42 others, Cavestro, G. M., Chaffee, K. G., Chanock, S. J., Cleary, S. P., Cotterchio, M., Foretova, L., Fuchs, C., Funel, N., Gazouli, M., Hassan, M., Herman, J. M., Holcatova, I., Holly, E. A., Hoover, R. N., Hung, R. J., Janout, V., Key, T. J., Kupcinskas, J., Kurtz, R. C., Landi, S., Lu, L., Malecka-Panas, E., Mambrini, A., Mohelnikova-Duchonova, B., Neoptolemos, J. P., Oberg, A. L., Orlow, I., Pasquali, C., Pezzilli, R., Rizzato, C., Saldia, A., Scarpa, A., Stolzenberg-Solomon, R. Z., Strobel, O., Tavano, F., Vashist, Y. K., Vodicka, P., Wolpin, B. M., Yu, H., Petersen, G. M., Risch, H. A. & Klein, A. P., Aug 30 2015, In : Nature Genetics. 47, 8, p. 911-916 6 p.

Research output: Contribution to journalArticle

115 Scopus citations

Detection of DNA damage in peripheral blood mononuclear cells from pancreatic cancer patients

Jansen, R. J., Fonseca-Williams, S., Bamlet, W. R., Ayala-Peña, S., Oberg, A. L., Petersen, G. M. & Torres-Ramos, C. A., Oct 1 2015, In : Molecular Carcinogenesis. 54, 10, p. 1220-1226 7 p.

Research output: Contribution to journalArticle

2 Scopus citations