• 9122 Citations
  • 55 Scopus h-Index
19962020
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Research Output 1996 2019

  • 9122 Citations
  • 55 Scopus h-Index
  • 168 Article
  • 1 Chapter
  • 1 Conference contribution
  • 1 Review article
2019
1 Citation (Scopus)

53BP1 as a potential predictor of response in PARP inhibitor-treated homologous recombination-deficient ovarian cancer

Hurley, R. M., Wahner Hendrickson, A. E., Visscher, D. W., Ansell, P., Harrell, M. I., Wagner, J. M., Negron, V., Goergen, K. M., Maurer, M. J., Oberg, A. L., Meng, X. W., Flatten, K. S., De Jonge, M. J. A., Van Herpen, C. D., Gietema, J. A., Koornstra, R. H. T., Jager, A., den Hollander, M. W., Dudley, M., Shepherd, S. P. & 2 others, Swisher, E. M. & Kaufmann, S. H., Jan 1 2019, (Accepted/In press) In : Gynecologic Oncology.

Research output: Contribution to journalArticle

Homologous Recombination
Ovarian Neoplasms
DNA End-Joining Repair
Neoplasms
Gene Deletion

Genes associated with bowel metastases in ovarian cancer

Mariani, A., Wang, C., Oberg, A. L., Riska, S. M., Torres, M., Kumka, J., Multinu, F., Sagar, G., Roy, D., Jung, DB. B., Zhang, Q., Grassi, T., Visscher, D. W., Patel, V. P., Jin, L., Staub, J. K., Cliby, W. A., Weroha, S. J., Kalli, K. R., Hartmann, L. C. & 3 others, Kaufmann, S. H., Goode, E. L. & Shridhar, V., Jan 1 2019, In : Gynecologic oncology.

Research output: Contribution to journalArticle

Open Access
Ovarian Neoplasms
Neoplasm Metastasis
Genes
Neoplasms
Immunohistochemistry
1 Citation (Scopus)

Risk of Different Cancers Among First-degree Relatives of Pancreatic Cancer Patients: Influence of Probands' Susceptibility Gene Mutation Status

Antwi, S., Fagan, S. E., Chaffee, K. G., Bamlet, W. R., Hu, C., Polley, E., Hart, S., Shimelis, H., Lilyquist, J., Gnanaolivu, R. D., Mc Williams, R. R., Oberg, A. L., Couch, F. J. & Petersen, G. M., Mar 1 2019, In : Journal of the National Cancer Institute. 111, 3, p. 264-271 8 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Mutation
Genes
Confidence Intervals
Neoplasms
1 Citation (Scopus)

Serum Proteomics on the Basis of Discovery of Predictive Biomarkers of Response to Androgen Deprivation Therapy in Advanced Prostate Cancer

Kohli, M., Oberg, A. L., Mahoney, D. W., Riska, S. M., Sherwood, R., Zhang, Y., Zenka, R. M., Sahasrabudhe, D., Qin, R. & Zhang, S., Jan 1 2019, In : Clinical Genitourinary Cancer.

Research output: Contribution to journalArticle

Proteomics
Androgens
Prostatic Neoplasms
Biomarkers
Serum
2018
2 Citations (Scopus)

Colonoscopy surveillance for high risk polyps does not always prevent colorectal cancer

Mouchli, M. A., Ouk, L., Scheitel, M. R., Chaudhry, A. P., Felmlee-Devine, D., Grill, D. E., Rashtak, S., Wang, P., Wang, J., Chaudhry, R., Smyrk, T. C., Oberg, A. L., Druliner, B. R. & Boardman, L. A., Feb 28 2018, In : World Journal of Gastroenterology. 24, 8, p. 905-916 12 p.

Research output: Contribution to journalArticle

Colonoscopy
Polyps
Adenoma
Colorectal Neoplasms
Risk Management
10 Citations (Scopus)

Constitutive Interferon Pathway Activation in Tumors as an Efficacy Determinant Following Oncolytic Virotherapy

Kurokawa, C., Iankov, I. D., Anderson, S. K., Aderca, I., Leontovich, A. A., Maurer, M. J., Oberg, A. L., Schroeder, M. A., Giannini, C., Greiner, S. M., Becker, M. A., Thompson, E. A., Haluska, P., Jentoft, M. E., Parney, I. F., Weroha, S. J., Jen, J., Sarkaria, J. N. & Galanis, E., Oct 1 2018, In : Journal of the National Cancer Institute. 110, 10, p. 1123-1132 10 p.

Research output: Contribution to journalArticle

Oncolytic Virotherapy
Measles virus
Interferons
Glioblastoma
Heterografts
17 Citations (Scopus)

Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer

Klein, A. P., Wolpin, B. M., Risch, H. A., Stolzenberg-Solomon, R. Z., Mocci, E., Zhang, M., Canzian, F., Childs, E. J., Hoskins, J. W., Jermusyk, A., Zhong, J., Chen, F., Albanes, D., Andreotti, G., Arslan, A. A., Babic, A., Bamlet, W. R., Beane-Freeman, L., Berndt, S. I., Blackford, A. & 103 others, Borges, M., Borgida, A., Bracci, P. M., Brais, L., Brennan, P., Brenner, H., Bueno-De-Mesquita, B., Buring, J., Campa, D., Capurso, G., Cavestro, G. M., Chaffee, K. G., Chung, C. C., Cleary, S., Cotterchio, M., Dijk, F., Duell, E. J., Foretova, L., Fuchs, C., Funel, N., Gallinger, S., Gaziano, J. M. M., Gazouli, M., Giles, G. G., Giovannucci, E., Goggins, M., Goodman, G. E., Goodman, P. J., Hackert, T., Haiman, C., Hartge, P., Hasan, M., Hegyi, P., Helzlsouer, K. J., Herman, J., Holcatova, I., Holly, E. A., Hoover, R., Hung, R. J., Jacobs, E. J., Jamroziak, K., Janout, V., Kaaks, R., Khaw, K. T., Klein, E. A., Kogevinas, M., Kooperberg, C., Kulke, M. H., Kupcinskas, J., Kurtz, R. J., Laheru, D., Landi, S., Lawlor, R. T., Lee, I. M., Lemarchand, L., Lu, L., Malats, N., Mambrini, A., Mannisto, S., Milne, R. L., Mohelníková-Duchoňová, B., Neale, R. E., Neoptolemos, J. P., Oberg, A. L., Olson, S. H., Orlow, I., Pasquali, C., Patel, A. V., Peters, U., Pezzilli, R., Porta, M., Real, F. X., Rothman, N., Scelo, G., Sesso, H. D., Severi, G., Shu, X. O., Silverman, D., Smith, J. P., Soucek, P., Sund, M., Talar-Wojnarowska, R., Tavano, F., Thornquist, M. D., Tobias, G. S., Van Den Eeden, S. K., Vashist, Y., Visvanathan, K., Vodicka, P., Wactawski-Wende, J., Wang, Z., Wentzensen, N., White, E., Yu, H., Yu, K., Zeleniuch-Jacquotte, A., Zheng, W., Kraft, P., Li, D., Chanock, S., Obazee, O., Petersen, G. M. & Amundadottir, L. T., Dec 1 2018, In : Nature Communications. 9, 1, 556.

Research output: Contribution to journalArticle

genome
loci
Pancreatic Neoplasms
Meta-Analysis
Genes
4 Citations (Scopus)

Molecular characterization of colorectal adenomas with and without malignancy reveals distinguishing genome, transcriptome and methylome alterations

Druliner, B. R., Wang, P., Bae, T., Baheti, S., Slettedahl, S., Mahoney, D., Vasmatzis, N., Xu, H., Kim, M., Bockol, M., O'Brien, D., Grill, D., Warner, N., Munoz-Gomez, M., Kossick, K., Johnson, R., Mouchli, M., Felmlee-Devine, D., Washechek-Aletto, J., Smyrk, T. C. & 6 others, Oberg, A. L., Wang, J., Chia, N. D., Abyzov, A., Ahlquist, D. & Boardman, L. A., Dec 1 2018, In : Scientific Reports. 8, 1, 3161.

Research output: Contribution to journalArticle

Polyps
Transcriptome
Adenoma
Genome
Neoplasms
3 Citations (Scopus)

Pancreatic cancer risk is modulated by inflammatory potential of diet and ABO genotype: A consortia-based evaluation and replication study

Antwi, S., Bamlet, W. R., Pedersen, K. S., Chaffee, K. G., Risch, H. A., Shivappa, N., Steck, S. E., Anderson, K. E., Bracci, P. M., Polesel, J., Serraino, D., La Vecchia, C., Bosetti, C., Li, D., Oberg, A. L., Arslan, A. A., Albanes, D., Duell, E. J., Huybrechts, I., Amundadottir, L. T. & 16 others, Hoover, R., Mannisto, S., Chanock, S. J., Zheng, W., Shu, X. O., Stepien, M., Canzian, F., Bueno-De-Mesquita, B., Quirós, J. R., Zeleniuch-Jacquotte, A., Bruinsma, F., Milne, R. L., Giles, G. G., Hébert, J. R., Stolzenberg-Solomon, R. Z. & Petersen, G. M., Jul 30 2018, In : Carcinogenesis. 39, 8, p. 1056-1067 12 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Genotype
Diet
Confidence Intervals
Case-Control Studies
13 Citations (Scopus)

Prevalence of germ-line mutations in cancer genes among pancreatic cancer patients with a positive family history

Chaffee, K. G., Oberg, A. L., Mc Williams, R. R., Majithia, N., Allen, B. A., Kidd, J., Singh, N., Hartman, A. R., Wenstrup, R. J. & Petersen, G. M., Jan 1 2018, In : Genetics in Medicine. 20, 1, p. 119-127 9 p.

Research output: Contribution to journalArticle

Germ-Line Mutation
Neoplasm Genes
Pancreatic Neoplasms
Adenocarcinoma
Mutation
2017
3 Citations (Scopus)

Association between alcohol consumption, folate intake, and risk of pancreatic cancer: A case-control study

Yallew, W., Bamlet, W. R., Oberg, A. L., Anderson, K. E., Olson, J. E., Sinha, R., Petersen, G. M., Stolzenberg-Solomon, R. Z. & Jansen, R. J., May 1 2017, In : Nutrients. 9, 5, 448.

Research output: Contribution to journalArticle

pancreatic neoplasms
case-control studies
Pancreatic Neoplasms
Folic Acid
folic acid
17 Citations (Scopus)

Bevacizumab may differentially improve ovarian cancer outcome in patients with proliferative and mesenchymal molecular subtypes

Kommoss, S., Winterhoff, B., Oberg, A. L., Konecny, G. E., Wang, C., Riska, S. M., Fan, J. B., Maurer, M. J., April, C., Shridhar, V., Kommoss, F., Du Bois, A., Hilpert, F., Mahner, S., Baumann, K., Schroeder, W., Burges, A., Canzler, U., Chien, J., Embleton, A. C. & 7 others, Parmar, M., Kaplan, R., Perren, T., Hartmann, L. C., Goode, E. L., Dowdy, S. C. & Pfisterer, J., Jul 15 2017, In : Clinical Cancer Research. 23, 14, p. 3794-3801 8 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Gene Expression
Bevacizumab
Health Care Costs
Molecular Biology
191 Citations (Scopus)

Cellular senescence mediates fibrotic pulmonary disease

Schafer, M. J., White, T. A., Iijima, K., Haak, A. J., Ligresti, G., Atkinson, E. J., Oberg, A. L., Birch, J., Salmonowicz, H., Zhu, Y., Mazula, D. L., Brooks, R. W., Fuhrmann-Stroissnigg, H., Pirtskhalava, T., Prakash, Y. S., Tchkonia, T., Robbins, P. D., Aubry, M. C., Passos, J., Kirkland, J. L. & 3 others, Tschumperlin, D. J., Kita, H. & LeBrasseur, N. K., Feb 23 2017, In : Nature Communications. 8, 14532.

Research output: Contribution to journalArticle

fibrosis
Pulmonary diseases
Cell Aging
Idiopathic Pulmonary Fibrosis
Lung Diseases
20 Citations (Scopus)

Combination epigenetic therapy in metastatic colorectal cancer (mCRC) with subcutaneous 5-azacitidine and entinostat; a phase 2 consortium/stand Up 2 cancer study

Azad, N. S., El-Khoueiry, A., Yin, J., Oberg, A. L., Flynn, P., Adkins, D., Sharma, A., Weisenberger, D. J., Brown, T., Medvari, P., Jones, P. A., Easwaran, H., Kamel, I., Bahary, N., Kim, G., Picus, J., Pitot, H. C., Erlichman, C., Donehower, R., Shen, H. & 4 others, Laird, P. W., Piekarz, R., Baylin, S. & Ahuja, N., 2017, In : Oncotarget. 8, 21, p. 35326-35338 13 p.

Research output: Contribution to journalArticle

Azacitidine
Epigenomics
Colorectal Neoplasms
Neoplasms
Therapeutics
47 Citations (Scopus)

Detection of early pancreatic ductal adenocarcinoma with thrombospondin-2 & CA19-9 blood markers

Kim, J., Bamlet, W. R., Oberg, A. L., Chaffee, K. G., Donahue, G., Cao, X. J., Chari, S. T., Garcia, B. A., Petersen, G. M. & Zaret, K. S., Jul 12 2017, In : Science Translational Medicine. 9, 398, eaah5583.

Research output: Contribution to journalArticle

Adenocarcinoma
Validation Studies
thrombospondin 2
Pancreatic Diseases
ROC Curve
7 Citations (Scopus)

EGFR as a prognostic biomarker and therapeutic target in ovarian cancer: Evaluation of patient cohort and literature review

Mehner, C., Oberg, A. L., Goergen, K. M., Kalli, K. R., Maurer, M. J., Nassar, A., Goode, E. L., Keeney, G., Jatoi, A., Radisky, D. C. & Radisky, E. S., May 1 2017, In : Genes and Cancer. 8, 5-6, p. 589-599 11 p.

Research output: Contribution to journalReview article

Epidermal Growth Factor Receptor
Ovarian Neoplasms
Biomarkers
Staining and Labeling
Therapeutics
5 Citations (Scopus)

Genetically predicted telomere length is not associated with pancreatic cancer risk

Antwi, S., Bamlet, W. R., Broderick, B. T., Chaffee, K. G., Oberg, A. L., Jatoi, A., Boardman, L. A. & Petersen, G. M., Jun 1 2017, In : Cancer Epidemiology Biomarkers and Prevention. 26, 6, p. 971-974 4 p.

Research output: Contribution to journalArticle

Telomere
Pancreatic Neoplasms
Alleles
Adenocarcinoma
Confidence Intervals
191 Citations (Scopus)

Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma

Raphael, B. J., Hruban, R. H., Aguirre, A. J., Moffitt, R. A., Yeh, J. J., Stewart, C., Robertson, A. G., Cherniack, A. D., Gupta, M., Getz, G., Gabriel, S. B., Meyerson, M., Cibulskis, C., Fei, S. S., Hinoue, T., Shen, H., Laird, P. W., Ling, S., Lu, Y., Mills, G. B. & 251 others, Akbani, R., Loher, P., Londin, E. R., Rigoutsos, I., Telonis, A. G., Gibb, E. A., Goldenberg, A., Mezlini, A. M., Hoadley, K. A., Collisson, E., Lander, E., Murray, B. A., Hess, J., Rosenberg, M., Bergelson, L., Zhang, H., Cho, J., Tiao, G., Kim, J., Livitz, D., Leshchiner, I., Reardon, B., Van Allen, E., Kamburov, A., Beroukhim, R., Saksena, G., Schumacher, S. E., Noble, M. S., Heiman, D. I., Gehlenborg, N., Kim, J., Lawrence, M. S., Adsay, V., Petersen, G. M., Klimstra, D., Bardeesy, N., Leiserson, M. D. M., Bowlby, R., Kasaian, K., Birol, I., Mungall, K. L., Sadeghi, S., Weinstein, J. N., Spellman, P. T., Liu, Y., Amundadottir, L. T., Tepper, J., Singhi, A. D., Dhir, R., Paul, D., Smyrk, T. C., Zhang, L., Kim, P., Bowen, J., Frick, J., Gastier-Foster, J. M., Gerken, M., Lau, K., Leraas, K. M., Lichtenberg, T. M., Ramirez, N. C., Renkel, J., Sherman, M., Wise, L., Yena, P., Zmuda, E., Shih, J., Ally, A., Balasundaram, M., Carlsen, R., Chu, A., Chuah, E., Clarke, A., Dhalla, N., Holt, R. A., Jones, S. J. M., Lee, D., Ma, Y., Marra, M. A., Mayo, M., Moore, R. A., Mungall, A. J., Schein, J. E., Sipahimalani, P., Tam, A., Thiessen, N., Tse, K., Wong, T., Brooks, D., Auman, J. T., Balu, S., Bodenheimer, T., Hayes, D. N., Hoyle, A. P., Jefferys, S. R., Jones, C. D., Meng, S., Mieczkowski, P. A., Mose, L. E., Perou, C. M., Perou, A. H., Roach, J., Shi, Y., Simons, J. V., Skelly, T., Soloway, M. G., Tan, D., Veluvolu, U., Parker, J. S., Wilkerson, M. D., Korkut, A., Senbabaoglu, Y., Burch, P., Mc Williams, R. R., Chaffee, K., Oberg, A. L., Zhang, W., Gingras, M. C., Wheeler, D. A., Xi, L., Albert, M., Bartlett, J., Sekhon, H., Stephen, Y., Howard, Z., Judy, M., Breggia, A., Shroff, R. T., Chudamani, S., Liu, J., Lolla, L., Naresh, R., Pihl, T., Sun, Q., Wan, Y., Wu, Y., Jennifer, S., Roggin, K., Becker, K. F., Behera, M., Bennett, J., Boice, L., Burks, E., Carlotti Junior, C. G., Chabot, J., Pretti da Cunha Tirapelli, D., Sebastião dos Santos, J., Dubina, M., Eschbacher, J., Huang, M., Huelsenbeck-Dill, L., Jenkins, R., Karpov, A., Kemp, R., Lyadov, V., Maithel, S., Manikhas, G., Montgomery, E., Noushmehr, H., Osunkoya, A., Owonikoko, T., Paklina, O., Potapova, O., Ramalingam, S., Rathmell, W. K., Rieger-Christ, K., Saller, C., Setdikova, G., Shabunin, A., Sica, G., Su, T., Sullivan, T., Swanson, P., Tarvin, K., Tavobilov, M., Thorne, L. B., Urbanski, S., Voronina, O., Wang, T., Crain, D., Curley, E., Gardner, J., Mallery, D., Morris, S., Paulauskis, J., Penny, R., Shelton, C., Shelton, T., Janssen, K. P., Bathe, O., Bahary, N., Slotta-Huspenina, J., Johns, A., Hibshoosh, H., Hwang, R. F., Sepulveda, A., Radenbaugh, A., Baylin, S. B., Berrios, M., Bootwalla, M. S., Holbrook, A., Lai, P. H., Maglinte, D. T., Mahurkar, S., Triche, T. J., Van Den Berg, D. J., Weisenberger, D. J., Chin, L., Kucherlapati, R., Kucherlapati, M., Pantazi, A., Park, P., Saksena, G., Voet, D., Lin, P., Frazer, S., Defreitas, T., Meier, S., Chin, L., Kwon, S. Y., Kim, Y. H., Park, S. J., Han, S. S., Kim, S. H., Kim, H., Furth, E., Tempero, M., Sander, C., Biankin, A., Chang, D., Bailey, P., Gill, A., Kench, J., Grimmond, S., Johns, A., Cancer Genome Initiative (APGI, A. P., Postier, R., Zuna, R., Sicotte, H., Demchok, J. A., Ferguson, M. L., Hutter, C. M., Mills Shaw, K. R., Sheth, M., Sofia, H. J., Tarnuzzer, R., Wang, Z., Yang, L., Zhang, J. J., Felau, I. & Zenklusen, J. C., Aug 14 2017, In : Cancer Cell. 32, 2, p. 185-203.e13

Research output: Contribution to journalArticle

Adenocarcinoma
Mutation
Exome
Neoplasms
Untranslated RNA
5 Citations (Scopus)

Integration of immune cell populations, mRNA-Seq, and CpG methylation to better predict humoral immunity to influenza vaccination: Dependence of mRNA-Seq/CpG methylation on immune cell populations

Zimmermann, M. T., Kennedy, R. B., Grill, D. E., Oberg, A. L., Goergen, K. M., Ovsyannikova, I. G., Haralambieva, I. H. & Poland, G. A., Apr 21 2017, In : Frontiers in Immunology. 8, APR, 445.

Research output: Contribution to journalArticle

Humoral Immunity
Methylation
Human Influenza
Blood Cells
Vaccination
1 Citation (Scopus)

Multicohort analysis reveals baseline transcriptional predictors of influenza vaccination responses

Avey, S., Cheung, F., Fermin, D., Frelinger, J., Gaujoux, R., Gottardo, R., Khatri, P., Kleinstein, S. H., Kotliarov, Y., Meng, H., Sauteraud, R., Shen-Orr, S. S., Tsang, J. S., Vallania, F., Anguiano, E., Baisch, J., Baldwin, N., Belshe, R. B., Blevins, T. P., Chaussabel, D. & 25 others, Davis, M. M., Fikrig, E., Grill, D. E., Hafler, D. A., Henrich, E., Joshi, S. R., Kaech, S. M., Kennedy, R. B., Mohanty, S., Montgomery, R. R., Oberg, A. L., Obermoser, G., Ovsyannikova, I. G., Karolina Palucka, A., Pascual, V., Poland, G. A., Pulendran, B., Reinherz, E. L., Shaw, A. C., Siconolfi, B., Stuart, K. D., Tsang, S., Ueda, I., Wilson, J. & Zapata, H. J., Apr 25 2017, In : Science Immunology. 2, 14, eaal4656.

Research output: Contribution to journalArticle

Open Access
Human Influenza
Vaccination
Antibody Formation
Allergy and Immunology
Gene Regulatory Networks
21 Citations (Scopus)

Pooled clustering of high-grade serous ovarian cancer gene expression leads to novel consensus subtypes associated with survival and surgical outcomes

Wang, C., Armasu, S. M., Kalli, K. R., Maurer, M. J., Heinzen, E. P., Keeney, G., Cliby, W. A., Oberg, A. L., Kaufmann, S. H. & Goode, E. L., Aug 1 2017, In : Clinical Cancer Research. 23, 15, p. 4077-4085 9 p.

Research output: Contribution to journalArticle

Neoplasm Genes
Ovarian Neoplasms
Cluster Analysis
Gene Expression
Survival
2016
59 Citations (Scopus)

Analysis of heritability and shared heritability based on genome-wide association studies for thirteen cancer types

Sampson, J. N., Wheeler, W. A., Yeager, M., Panagiotou, O., Wang, Z., Berndt, S. I., Lan, Q., Abnet, C. C., Amundadottir, L. T., Figueroa, J. D., Landi, M. T., Mirabello, L., Savage, S. A., Taylor, P. R., De Vivo, I., McGlynn, K. A., Purdue, M. P., Rajaraman, P., Adami, H. O., Ahlbom, A. & 388 others, Albanes, D., Amary, M. F., An, S. J., Andersson, U., Andriole, G., Andrulis, I. L., Angelucci, E., Ansell, S. M., Arici, C., Armstrong, B. K., Arslan, A. A., Austin, M. A., Baris, D., Barkauskas, D. A., Bassig, B. A., Becker, N., Benavente, Y., Benhamou, S., Berg, C., Van Den Berg, D., Bernstein, L., Bertrand, K. A., Birmann, B. M., Black, A., Shanafelt, T. D., Boffetta, P., Boutron-Ruault, M. C., Bracci, P. M., Brinton, L., Brooks-Wilson, A. R., Bueno-De-Mesquita, H. B., Burdett, L., Buring, J., Butler, M. A., Cai, Q., Cancel-Tassin, G., Canzian, F., Carrato, A., Carreon, T., Carta, A., Chan, J. K. C., Chang, E. T., Chang, G. C., Chang, I. S., Chang, J., Chang-Claude, J., Chen, C. J., Chen, C. Y., Chen, C., Chen, C. H., Chen, C., Chen, H., Chen, K., Chen, K. Y., Chen, K. C., Chen, Y., Chen, Y. H., Chen, Y. S., Chen, Y. M., Chien, L. H., Chirlaque, M. D., Choi, J. E., Choi, Y. Y., Chow, W. H., Chung, C. C., Clavel, J., Clavel-Chapelon, F., Cocco, P., Colt, J. S., Comperat, E., Conde, L., Connors, J. M., Conti, D., Cortessis, V. K., Cotterchio, M., Cozen, W., Crouch, S., Crous-Bou, M., Cussenot, O., Davis, F. G., Ding, T., Diver, W. R., Dorronsoro, M., Dossus, L., Duell, E. J., Ennas, M. G., Erickson, R. L., Feychting, M., Flanagan, A. M., Foretova, L., Fraumeni, J. F., Freedman, N. D., Freeman, L. E. B., Fuchs, C., Gago-Dominguez, M., Gallinger, S., Gao, Y. T., Gapstur, S. M., Garcia-Closas, M., García-Closas, R., Gascoyne, R. D., Gastier-Foster, J., Gaudet, M. M., Gaziano, J. M., Giffen, C., Giles, G. G., Giovannucci, E., Glimelius, B., Goggins, M., Gokgoz, N., Goldstein, A. M., Gorlick, R., Gross, M., Grubb, R., Gu, J., Guan, P., Gunter, M., Guo, H., Habermann, T. M., Haiman, C. A., Halai, D., Hallmans, G., Hassan, M., Hattinger, C., He, Q., He, X., Helzlsouer, K., Henderson, B., Henriksson, R., Hjalgrim, H., Hoffman-Bolton, J., Hohensee, C., Holford, T. R., Holly, E. A., Hong, Y. C., Hoover, R. N., Horn-Ross, P. L., Hosain, G. M. M., Hosgood, H. D., Hsiao, C. F., Hu, N., Hu, W., Hu, Z., Huang, M. S., Huerta, J. M., Hung, J. Y., Hutchinson, A., Inskip, P. D., Jackson, R. D., Jacobs, E. J., Jenab, M., Jeon, H. S., Ji, B. T., Jin, G., Jin, L., Johansen, C., Johnson, A., Jung, Y. J., Kaaks, R., Kamineni, A., Kane, E., Kang, C. H., Karagas, M. R., Kelly, R. S., Khaw, K. T., Kim, C., Kim, H. N., Kim, J. H., Kim, J. S., Kim, Y. H., Kim, Y. T., Kim, Y. C., Kitahara, C. M., Klein, A. P., Klein, R. J., Kogevinas, M., Kohno, T., Kolonel, L. N., Kooperberg, C., Kricker, A., Krogh, V., Kunitoh, H., Kurtz, R. C., Kweon, S. S., La Croix, A., Lawrence, C., Lecanda, F., Lee, V. H. F., Li, D., Li, H., Li, J., Li, Y. J., Li, Y., Liao, L. M., Liebow, M., Lightfoot, T., Lim, W. Y., Lin, C. C., Lin, D., Lindstrom, S., Linet, M. S., Link, B. K., Liu, C., Liu, J., Liu, L., Ljungberg, B., Lloreta, J., Di Lollo, S., Lu, D., Lund, E., Malats, N., Mannisto, S., Marchand, L. L., Marina, N., Masala, G., Mastrangelo, G., Matsuo, K., Maynadie, M., McKay, J., McKean-Cowdin, R., Melbye, M., Melin, B. S., Michaud, D. S., Mitsudomi, T., Monnereau, A., Montalvan, R., Moore, L. E., Mortensen, L. M., Nieters, A., North, K. E., Novak, A. J., Oberg, A. L., Offit, K., Oh, I. J., Olson, S. H., Palli, D., Pao, W., Park, I. K., Park, J. Y., Park, K. H., Patiño-Garcia, A., Pavanello, S., Peeters, P. H. M., Perng, R. P., Peters, U., Petersen, G. M., Picci, P., Pike, M. C., Porru, S., Prescott, J., Prokunina-Olsson, L., Qian, B., Qiao, Y. L., Rais, M., Riboli, E., Riby, J., Risch, H. A., Rizzato, C., Rodabough, R., Roman, E., Roupret, M., Ruder, A. M., De Sanjose, S., Scelo, G., Schned, A., Schumacher, F., Schwartz, K., Schwenn, M., Scotlandi, K., Seow, A., Serra, C., Serra, M., Sesso, H. D., Setiawan, V. W., Severi, G., Severson, R. K., Shanafelt, T. D., Shen, H., Shen, W., Shin, M. H., Shiraishi, K., Shu, X. O., Siddiq, A., Sierrasesúmaga, L., Sihoe, A. D. L., Skibola, C. F., Smith, A., Smith, M. T., Southey, M. C., Spinelli, J. J., Staines, A., Stampfer, M., Stern, M. C., Stevens, V. L., Stolzenberg-Solomon, R. S., Su, J., Su, W. C., Sund, M., Sung, J. S., Sung, S. W., Tan, W., Tang, W., Tardón, A., Thomas, D., Thompson, C. A., Tinker, L. F., Tirabosco, R., Tjønneland, A., Travis, R. C., Trichopoulos, D., Tsai, F. Y., Tsai, Y. H., Tucker, M., Turner, J., Vajdic, C. M., Vermeulen, R. C. H., Villano, D. J., Vineis, P., Virtamo, J., Visvanathan, K., Wactawski-Wende, J., Wang, C., Wang, C. L., Wang, J. C., Wang, J., Wei, F., Weiderpass, E., Weiner, G. J., Weinstein, S., Wentzensen, N., White, E., Witzig, T. E., Wolpin, B. M., Wong, M. P., Wu, C., Wu, G., Wu, J., Wu, T., Wu, W., Wu, X., Wu, Y. L., Wunder, J. S., Xiang, Y. B., Xu, J., Xu, P., Yang, P. C., Yang, T. Y., Ye, Y., Yin, Z., Yokota, J., Yoon, H. I., Yu, C. J., Yu, H., Yu, K., Yuan, J. M., Zelenetz, A., Zeleniuch-Jacquotte, A., Zhang, X. C., Zhang, Y., Zhao, X., Zhao, Z., Zheng, H., Zheng, T., Zheng, W., Zhou, B., Zhu, M., Zucca, M., Boca, S. M., Cerhan, J. R., Ferri, G. M., Hartge, P., Hsiung, C. A., Magnani, C., Miligi, L., Morton, L. M., Smedby, K. E., Teras, L. R., Vijai, J., Wang, S. S., Brennan, P., Caporaso, N. E., Hunter, D. J., Kraft, P., Rothman, N., Silverman, D. T., Slager, S. L., Chanock, S. J. & Chatterjee, N., 2016, In : Journal of the National Cancer Institute. 107, 12, djv279.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Smoking
Neoplasms
Lung Neoplasms
Confidence Intervals
4 Citations (Scopus)

An interaction quantitative trait loci tool implicates epistatic functional variants in an apoptosis pathway in smallpox vaccine eQTL data

Lareau, C. A., White, B. C., Oberg, A. L., Kennedy, R. B., Poland, G. A. & McKinney, B. A., Jun 1 2016, In : Genes and Immunity. 17, 4, p. 244-250 7 p.

Research output: Contribution to journalArticle

Smallpox Vaccine
Quantitative Trait Loci
Apoptosis
Gene Expression
Smallpox
13 Citations (Scopus)

APOBEC3G expression correlates with T-cell infiltration and improved clinical outcomes in high-grade serous ovarian carcinoma

Leonard, B., Starrett, G. J., Maurer, M. J., Oberg, A. L., Van Bockstal, M., Van Dorpe, J., De Wever, O., Helleman, J., Sieuwerts, A. M., Berns, E. M. J. J., Martens, J. W. M., Anderson, B. D., Brown, W. L., Kalli, K. R., Kaufmann, S. H. & Harris, R. S., Sep 15 2016, In : Clinical Cancer Research. 22, 18, p. 4746-4755 10 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Carcinoma
T-Lymphocytes
Neoplasms
Tumor-Infiltrating Lymphocytes
15 Citations (Scopus)

EUS-guided fine-needle injection of gemcitabine for locally advanced and metastatic pancreatic cancer

Levy, M. J., Alberts, S. R., Bamlet, W. R., Burch, P. A., Farnell, M. B., Gleeson, F. C., Haddock, M., Kendrick, M. L., Oberg, A. L., Petersen, G. M., Takahashi, N. & Chari, S. T., Jul 21 2016, (Accepted/In press) In : Gastrointestinal Endoscopy.

Research output: Contribution to journalArticle

gemcitabine
Pancreatic Neoplasms
Needles
Injections
Survival
7 Citations (Scopus)

Gene signatures associated with adaptive humoral immunity following seasonal influenza A/H1N1 vaccination

Ovsyannikova, I. G., Salk, H. M., Kennedy, R. B., Haralambieva, I. H., Zimmermann, M. T., Grill, D. E., Oberg, A. L. & Poland, G. A., Aug 18 2016, (Accepted/In press) In : Genes and Immunity.

Research output: Contribution to journalArticle

Adaptive Immunity
Humoral Immunity
Human Influenza
Hemagglutination
Vaccination
11 Citations (Scopus)

Gene signatures related to HAI response following influenza A/H1N1 vaccine in older individuals

Ovsyannikova, I. G., Oberg, A. L., Kennedy, R. B., Zimmermann, M. T., Haralambieva, I. H., Goergen, K. M., Grill, D. E. & Poland, G. A., May 1 2016, In : Heliyon. 2, 5, e00098.

Research output: Contribution to journalArticle

Human Influenza
Vaccines
Genes
Antibody Formation
Vaccination
15 Citations (Scopus)

Immunosenescence-related transcriptomic and immunologic changes in older individuals following influenza vaccination

Kennedy, R. B., Ovsyannikova, I. G., Haralambieva, I. H., Oberg, A. L., Zimmermann, M. T., Grill, D. E. & Poland, G. A., Nov 2 2016, In : Frontiers in Immunology. 7, NOV, 450.

Research output: Contribution to journalArticle

Human Influenza
Vaccination
MicroRNAs
T-Lymphocytes
Antigen Presentation
10 Citations (Scopus)
Exosomes
Immunosuppressive Agents
Pancreatic Neoplasms
Monocytes
Neoplasms
17 Citations (Scopus)

In vivo anti-tumor activity of the PARP inhibitor niraparib in homologous recombination deficient and proficient ovarian carcinoma

AlHilli, M. M., Becker, M. A., Weroha, S. J., Flatten, K. S., Hurley, R. M., Harrell, M. I., Oberg, A. L., Maurer, M. J., Hawthorne, K. M., Hou, X., Harrington, S. C., McKinstry, S., Meng, X. W., Wilcoxen, K. M., Kalli, K. R., Swisher, E. M., Kaufmann, S. H. & Haluska, P., Nov 1 2016, In : Gynecologic Oncology. 143, 2, p. 379-388 10 p.

Research output: Contribution to journalArticle

Homologous Recombination
Carcinoma
Heterografts
Neoplasms
Mutation
32 Citations (Scopus)

Metformin use and survival of patients with pancreatic cancer: A cautionary lesson

Chaiteerakij, R., Petersen, G. M., Bamlet, W. R., Chaffee, K. G., Zhen, D. B., Burch, P. A., Leof, E. R., Roberts, L. R. & Oberg, A. L., Jun 1 2016, In : Journal of Clinical Oncology. 34, 16, p. 1898-1904 7 p.

Research output: Contribution to journalArticle

Metformin
Pancreatic Neoplasms
Survival
Adenocarcinoma
Proportional Hazards Models
20 Citations (Scopus)

Optimizing Mass Spectrometry Analyses: A Tailored Review on the Utility of Design of Experiments

Hecht, E. S., Oberg, A. L. & Muddiman, D. C., May 1 2016, In : Journal of the American Society for Mass Spectrometry. 27, 5, p. 767-785 19 p.

Research output: Contribution to journalArticle

Design of experiments
Mass spectrometry
Mass Spectrometry
Post Translational Protein Processing
Mass spectrometers
30 Citations (Scopus)

Pancreatic cancer: Associations of inflammatory potential of diet, cigarette smoking and long-standing diabetes

Antwi, S., Oberg, A. L., Shivappa, N., Bamlet, W. R., Chaffee, K. G., Steck, S. E., Hébert, J. R. & Petersen, G. M., May 1 2016, In : Carcinogenesis. 37, 5, p. 481-490 10 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Smoking
Diet
Odds Ratio
Confidence Intervals
5 Citations (Scopus)

Recursive indirect-paths modularity (RIP-M) for detecting community structure in RNA-seq co-expression networks

Rahmani, B., Zimmermann, M. T., Grill, D. E., Kennedy, R. B., Oberg, A. L., White, B. C., Poland, G. A. & McKinney, B. A., May 9 2016, In : Frontiers in Genetics. 7, MAY, 80.

Research output: Contribution to journalArticle

Gene Regulatory Networks
RNA
Cluster Analysis
Influenza Vaccines
Multigene Family
13 Citations (Scopus)

System-wide associations between DNA-methylation, gene expression, and humoral immune response to influenza vaccination

Zimmermann, M. T., Oberg, A. L., Grill, D. E., Ovsyannikova, I. G., Haralambieva, I. H., Kennedy, R. B. & Poland, G. A., Mar 31 2016, In : PLoS One. 11, 3, e0152034.

Research output: Contribution to journalArticle

Methylation
DNA methylation
DNA Methylation
Humoral Immunity
Gene expression
5 Citations (Scopus)

The composition of immune cells serves as a predictor of adaptive immunity in a cohort of 50- to 74-year-old adults

Kennedy, R. B., Simon, W. L., Gibson, M. J., Goergen, K. M., Grill, D. E., Oberg, A. L. & Poland, G. A., 2016, (Accepted/In press) In : Immunology.

Research output: Contribution to journalArticle

Adaptive Immunity
Vaccination
Human Influenza
B-Lymphocyte Subsets
Enzyme-Linked Immunospot Assay
3 Citations (Scopus)

The integration of epistasis network and functional interactions in a GWAS implicates RXR pathway genes in the immune response to smallpox vaccine

McKinney, B. A., Lareau, C., Oberg, A. L., Kennedy, R. B., Ovsyannikova, I. G. & Poland, G. A., Aug 1 2016, In : PLoS One. 11, 8, e0158016.

Research output: Contribution to journalArticle

Smallpox Vaccine
Genome-Wide Association Study
epistasis
Genes
immune response
25 Citations (Scopus)

Three new pancreatic cancer susceptibility signals identified on chromosomes 1q32.1, 5p15.33 and 8q24.21

Zhang, M., Wang, Z., Obazee, O., Jia, J., Childs, E. J., Hoskins, J., Figlioli, G., Mocci, E., Collins, I., Chung, C. C., Hautman, C., Arslan, A. A., Beane-Freeman, L., Bracci, P. M., Buring, J., Duell, E. J., Gallinger, S., Giles, G. G., Goodman, G. E., Goodman, P. J. & 103 others, Kamineni, A., Kolonel, L. N., Kulke, M. H., Malats, N., Olson, S. H., Sesso, H. D., Visvanathan, K., White, E., Zheng, W., Abnet, C. C., Albanes, D., Andreotti, G., Brais, L., Bas Bueno-de-Mesquita, H., Basso, D., Berndt, S. I., Boutron-Ruault, M. C., Bijlsma, M. F., Brenner, H., Burdette, L., Campa, D., Caporaso, N. E., Capurso, G., Cavestro, G. M., Cotterchio, M., Costello, E., Elena, J., Boggi, U., Michael Gaziano, J., Gazouli, M., Giovannucci, E. L., Goggins, M., Gross, M., Haiman, C. A., Hassan, M., Helzlsouer, K. J., Hu, N., Hunter, D. J., Iskierka-Jazdzewska, E., Jenab, M., Kaaks, R., Key, T. J., Khaw, K. T., Klein, E. A., Kogevinas, M., Krogh, V., Kupcinskas, J., Kurtz, R. C., Landi, M. T., Landi, S., Marchand, L. L., Mambrini, A., Mannisto, S., Milne, R. L., Neale, R. E., Oberg, A. L., Panico, S., Patel, A. V., Peeters, P. H. M., Peters, U., Pezzilli, R., Porta, M., Purdue, M., Ramón Quiros, J., Riboli, E., Rothman, N., Scarpa, A., Scelo, G., Shu, X. O., Silverman, D. T., Soucek, P., Strobel, O., Sund, M., Malecka-Panas, E., Taylor, P. R., Tavano, F., Travis, R. C., Thornquist, M., Tjønneland, A., Tobias, G. S., Trichopoulos, D., Vashist, Y., Vodicka, P., Wactawski-Wende, J., Wentzensen, N., Yu, H., Yu, K., Zeleniuch-Jacquotte, A., Kooperberg, C., Risch, H. A., Jacobs, E. J., Li, D., Fuchs, C., Hoover, R., Hartge, P., Chanock, S. J., Petersen, G. M., Stolzenberg-Solomon, R. S., Wolpin, B. M., Kraft, P., Klein, A. P., Canzian, F. & Amundadottir, L. T., 2016, In : Oncotarget. 7, 41, p. 66328-66343 16 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Chromosomes
Genome-Wide Association Study
Odds Ratio
Single Nucleotide Polymorphism
4 Citations (Scopus)

Time Lapse to Colorectal Cancer: Telomere Dynamics Define the Malignant Potential of Polyps

Druliner, B. R., Ruan, X., Johnson, R., Grill, D., O'Brien, D., Lai, T. P., Rashtak, S., Felmlee-Devine, D., Washechek-Aletto, J., Malykh, A., Smyrk, T. C., Oberg, A. L., Liu, H. D., Shay, J. W., Ahlquist, D. A. & Boardman, L. A., Sep 1 2016, In : Clinical and Translational Gastroenterology. 7, 9, e188.

Research output: Contribution to journalArticle

Telomere
Polyps
Colorectal Neoplasms
Neoplasms
Adenoma
11 Citations (Scopus)

Transcriptional signatures of influenza A/H1N1-specific IgG memory-like B cell response in older individuals

Haralambieva, I. H., Ovsyannikova, I. G., Kennedy, R. B., Zimmermann, M. T., Grill, D. E., Oberg, A. L. & Poland, G. A., Jul 25 2016, In : Vaccine. 34, 34, p. 3993-4002 10 p.

Research output: Contribution to journalArticle

influenza
Human Influenza
B-lymphocytes
Vaccination
B-Lymphocytes
6 Citations (Scopus)

Whole transcriptome profiling identifies CD93 and other plasma cell survival factor genes associated with measles-specific antibody response after vaccination

Haralambieva, I. H., Zimmermann, M. T., Ovsyannikova, I. G., Grill, D. E., Oberg, A. L., Kennedy, R. B. & Poland, G. A., Aug 1 2016, In : PLoS One. 11, 8, e0160970.

Research output: Contribution to journalArticle

plasma cells
Measles
Gene Expression Profiling
Plasma Cells
transcriptomics
2015
97 Citations (Scopus)

Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer

Childs, E. J., Mocci, E., Campa, D., Bracci, P. M., Gallinger, S., Goggins, M., Li, D., Neale, R. E., Olson, S. H., Scelo, G., Amundadottir, L. T., Bamlet, W. R., Bijlsma, M. F., Blackford, A., Borges, M., Brennan, P., Brenner, H., Bueno-De-Mesquita, H. B., Canzian, F., Capurso, G. & 42 others, Cavestro, G. M., Chaffee, K. G., Chanock, S. J., Cleary, S. P., Cotterchio, M., Foretova, L., Fuchs, C., Funel, N., Gazouli, M., Hassan, M., Herman, J. M., Holcatova, I., Holly, E. A., Hoover, R. N., Hung, R. J., Janout, V., Key, T. J., Kupcinskas, J., Kurtz, R. C., Landi, S., Lu, L., Malecka-Panas, E., Mambrini, A., Mohelnikova-Duchonova, B., Neoptolemos, J. P., Oberg, A. L., Orlow, I., Pasquali, C., Pezzilli, R., Rizzato, C., Saldia, A., Scarpa, A., Stolzenberg-Solomon, R. Z., Strobel, O., Tavano, F., Vashist, Y. K., Vodicka, P., Wolpin, B. M., Yu, H., Petersen, G. M., Risch, H. A. & Klein, A. P., Aug 30 2015, In : Nature Genetics. 47, 8, p. 911-916 6 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Odds Ratio
Confidence Intervals
Penetrance
DNA Mismatch Repair
1 Citation (Scopus)

Detection of DNA damage in peripheral blood mononuclear cells from pancreatic cancer patients

Jansen, R. J., Fonseca-Williams, S., Bamlet, W. R., Ayala-Peña, S., Oberg, A. L., Petersen, G. M. & Torres-Ramos, C. A., Oct 1 2015, In : Molecular Carcinogenesis. 54, 10, p. 1220-1226 7 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
DNA Damage
Blood Cells
Mitochondrial DNA
Adenocarcinoma
22 Citations (Scopus)

Detection of endometrial cancer via molecular analysis of DNA collected with vaginal tampons

Bakkum-Gamez, J. N., Wentzensen, N., Maurer, M. J., Hawthorne, K. M., Voss, J. S., Kroneman, T. N., Famuyide, A. O., Clayton, A. C., Halling, K. C., Kerr, S. E., Cliby, W. A., Dowdy, S. C., Kipp, B. R., Mariani, A., Oberg, A. L., Podratz, K. C., Shridhar, V. & Sherman, M. E., 2015, In : Gynecologic Oncology. 137, 1, p. 14-22 9 p.

Research output: Contribution to journalArticle

Menstrual Hygiene Products
Endometrial Neoplasms
Endometrium
DNA
Genes
12 Citations (Scopus)

Differential co-expression network centrality and machine learning feature selection for identifying susceptibility hubs in networks with scale-free structure

Lareau, C. A., White, B. C., Oberg, A. L. & McKinney, B. A., Jan 8 2015, In : BioData Mining. 8, 1, 5.

Research output: Contribution to journalArticle

Centrality
Susceptibility
Feature Selection
Learning systems
Feature extraction
19 Citations (Scopus)

Exposure to environmental chemicals and heavy metals, and risk of pancreatic cancer

Antwi, S., Eckert, E. C., Sabaque, C. V., Leof, E. R., Hawthorne, K. M., Bamlet, W. R., Chaffee, K. G., Oberg, A. L. & Petersen, G. M., Nov 1 2015, In : Cancer Causes and Control. 26, 11, p. 1583-1591 9 p.

Research output: Contribution to journalArticle

Environmental Exposure
Heavy Metals
Pancreatic Neoplasms
Chlorinated Hydrocarbons
Odds Ratio
7 Citations (Scopus)

Gene signature model for breast cancer risk prediction for women with sclerosing adenosis

Degnim, A. C., Nassar, A., Stallings-Mann, M., Keith Anderson, S., Oberg, A. L., Vierkant, R. A., Frank, R. D., Wang, C., Winham, S. J., Frost, M. H., Hartmann, L. C., Visscher, D. W. & Radisky, D. C., Aug 31 2015, In : Breast Cancer Research and Treatment. 152, 3, p. 687-694 8 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Genes
Breast Diseases
Neoplasms
Biomarkers
1 Citation (Scopus)

Impaired innate, humoral, and cellular immunity despite a take in smallpox vaccine recipients

Kennedy, R. B., Poland, G. A., Ovsyannikova, I. G., Oberg, A. L., Asmann, Y., Grill, D. E., Vierkant, R. A. & Jacobson, R. M., Dec 21 2015, (Accepted/In press) In : Vaccine.

Research output: Contribution to journalArticle

Smallpox Vaccine
Humoral Immunity
Innate Immunity
humoral immunity
Cellular Immunity
18 Citations (Scopus)

Lessons learned in the analysis of high-dimensional data in vaccinomics

Oberg, A. L., McKinney, B. A., Schaid, D. J., Pankratz, V. S., Kennedy, R. B. & Poland, G. A., 2015, (Accepted/In press) In : Vaccine.

Research output: Contribution to journalArticle

Vaccines
vaccines
vaccine development
Systems Biology
gold
26 Citations (Scopus)

Metformin suppresses pancreatic tumor growth with inhibition of NFκB/STAT3 inflammatory signaling

Tan, X. L., Bhattacharyya, K. K., Dutta, S. K., Bamlet, W. R., Rabe, K. G., Wang, E., Smyrk, T. C., Oberg, A. L., Petersen, G. M. & Mukhopadhyay, D., May 25 2015, In : Pancreas. 44, 4, p. 636-647 12 p.

Research output: Contribution to journalArticle

Metformin
Tumor Burden
Growth
Neoplasms
Carcinogenesis