Andreas S Beutler, MD

  • 1607 Citations
  • 23 Scopus h-Index
19952020

Research output per year

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Research Output

  • 1607 Citations
  • 23 Scopus h-Index
  • 58 Article
  • 1 Review article
Article

AAV for pain: Steps towards clinical translation

Beutler, A. S. & Reinhardt, M., 2009, In : Gene Therapy. 16, 4, p. 461-469 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

Advances in small bowel neuroendocrine neoplasia

Banck, M. S. & Beutler, A. S., Mar 2014, In : Current Opinion in Gastroenterology. 30, 2, p. 163-167 5 p.

Research output: Contribution to journalArticle

6 Scopus citations
15 Scopus citations

A slowly growing human cholangiocarcinoma is highly sensitive to HSVtk gene therapy

Banck, M. S., Meier-Abt, P., Gerloff, T., Hemmi, S. & Beutler, A. S., 2001, In : GI Cancer. 3, 5, p. 343-353 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

Carbamazepine is an inhibitor of histone deacetylases

Beutler, A. S., Li, S., Nicol, R. & Walsh, M. J., May 13 2005, In : Life Sciences. 76, 26, p. 3107-3115 9 p.

Research output: Contribution to journalArticle

72 Scopus citations

Clinical course of oxaliplatin-induced neuropathy: Results from the randomized phase III trial N08CB (Alliance)

Pachman, D. R., Qin, R., Seisler, D. K., Smith, E. M. L., Beutler, A. S., Ta, L. E., Lafky, J. M., Wagner-Johnston, N. D., Ruddy, K. J., Dakhil, S., Staff, N. P., Grothey, A. F. & Loprinzi, C. L., Oct 20 2015, In : Journal of Clinical Oncology. 33, 30, p. 3416-3422 7 p.

Research output: Contribution to journalArticle

86 Scopus citations
21 Scopus citations

Curing rat glioblastoma: Immunotherapy or graft rejection? [5] (multiple letters)

Beutler, A. S., Banck, M. S., Aguzzi, A., Wedekind, D., Hedrich, H. J. & Ilan, J., 1997, In : Science. 276, 5309, p. 20-21 2 p.

Research output: Contribution to journalArticle

11 Scopus citations

Diametrically opposite methylome-transcriptome relationships in high-and low-CpG promoter genes in postmitotic neural rat tissue

Hartung, T., Zhang, L., Kanwar, R., Khrebtukova, I., Reinhardt, M., Wang, C., Therneau, T. M., Banck, M. S., Schroth, G. P. & Beutler, A. S., May 2012, In : Epigenetics. 7, 5, p. 421-428 8 p.

Research output: Contribution to journalArticle

26 Scopus citations
94 Scopus citations

Exome-level comparison of primary well-differentiated neuroendocrine tumors and their cell lines

Boora, G. K., Kanwar, R., Kulkarni, A. A., Pleticha, J., Ames, M., Schroth, G., Beutler, A. S. & Banck, M. S., Jul 1 2015, In : Cancer genetics. 208, 7-8, p. 374-381 8 p.

Research output: Contribution to journalArticle

40 Scopus citations
16 Scopus citations
2 Scopus citations
4 Scopus citations

Genetic variation in EPHA contributes to sensitivity to paclitaxel-induced peripheral neuropathy

Marcath, L. A., Kidwell, K. M., Vangipuram, K., Gersch, C. L., Rae, J. M., Burness, M. L., Griggs, J. J., Van Poznak, C., Hayes, D. F., Smith, E. M. L., Henry, N. L., Beutler, A. S. & Hertz, D. L., Jan 1 2019, (Accepted/In press) In : British Journal of Clinical Pharmacology.

Research output: Contribution to journalArticle

High cerebrospinal fluid levels of interleukin-10 attained by AAV in dogs

Pleticha, J., Malkmus, S. A., Heilmann, L. F., Veesart, S. L., Rezek, R., Xu, Q., Yaksh, T. L. & Beutler, A. S., Feb 7 2015, In : Gene Therapy. 22, 2, p. 202-208 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Human interleukin-10 delivered intrathecally by self-complementary adeno-associated virus 8 induces xenogeneic transgene immunity without clinical neurotoxicity in swine

Unger, M. D., Pleticha, J., Heilmann, L. F., Newman, L. K., Maus, T. & Beutler, A. S., Jul 1 2018, In : Journal of Gene Medicine. 20, 7-8, e3026.

Research output: Contribution to journalArticle

Intraneural convection enhanced delivery of AAVrh20 for targeting primary sensory neurons

Pleticha, J., Jeng-Singh, C., Rezek, R., Zaibak, M. & Beutler, A. S., 2014, In : Molecular and Cellular Neuroscience. 60, p. 72-80 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Intrathecal gene transfer by adeno-associated virus for pain

Beutler, A. S., Banck, M. S., Walsh, C. E. & Milligan, E. D., Oct 2005, In : Current Opinion in Molecular Therapeutics. 7, 5, p. 431-439 9 p.

Research output: Contribution to journalArticle

36 Scopus citations

Intrathecal long-term gene expression by self-complementary adeno-associated virus type I suitable for chronic pain studies in rats

Storek, B., Harder, N. M., Banck, M. S., Wang, C., McCarty, D. M., Janssen, W. G. M., Morrison, J. H., Walsh, C. E. & Beutler, A. S., Jan 30 2006, In : Molecular Pain. 2, 4.

Research output: Contribution to journalArticle

42 Scopus citations

Laminotomy for lumbar dorsal root ganglion access and injection in swine

Unger, M. D., Maus, T., Puffer, R. C., Newman, L. K., Currier, B. L. & Beutler, A. S., Oct 10 2017, In : Journal of Visualized Experiments. 2017, 128, e56434.

Research output: Contribution to journalArticle

3 Scopus citations

Minimally invasive convection-enhanced delivery of biologics into dorsal root ganglia: Validation in the pig model and prospective modeling in humans

Pleticha, J., Maus, T., Christner, J. A., Marsh, M. P., Lee, K. H., Hooten, W. M. & Beutler, A. S., Oct 1 2014, In : Journal of Neurosurgery. 121, 4, p. 851-858 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

mRNA-seq with agnostic splice site discovery for nervous system transcriptomics tested in chronic pain

Hammer, P., Banck, M. S., Amberg, R., Wang, C., Petznick, G., Luo, S., Khrebtukova, I., Schroth, G. P., Beyerlein, P. & Beutler, A. S., Jun 2010, In : Genome Research. 20, 6, p. 847-860 14 p.

Research output: Contribution to journalArticle

50 Scopus citations

National Cancer Institute-supported chemotherapy-induced peripheral neuropathy trials: outcomes and lessons

Majithia, N., Temkin, S. M., Ruddy, K. J., Beutler, A. S., Hershman, D. L. & Loprinzi, C. L., Mar 1 2016, In : Supportive Care in Cancer. 24, 3, p. 1439-1447 9 p.

Research output: Contribution to journalArticle

51 Scopus citations

Neurological safety of oxaliplatin in patients with uncommon variants in Charcot-Marie-tooth disease genes

Le-Rademacher, J. G., Lopez, C. L., Kanwar, R., Major-Elechi, B., Abyzov, A., Banck, M. S., Therneau, T. M., Sloan, J. A., Loprinzi, C. L. & Beutler, A. S., Apr 15 2020, In : Journal of the neurological sciences. 411, 116687.

Research output: Contribution to journalArticle

Open Access

Patient-reported (EORTC QLQ-CIPN20) versus physician-reported (CTCAE) quantification of oxaliplatin- and paclitaxel/carboplatin-induced peripheral neuropathy in NCCTG/Alliance clinical trials

Le-Rademacher, J., Kanwar, R., Seisler, D., Pachman, D. R., Qin, R., Abyzov, A., Ruddy, K. J., Banck, M. S., Lavoie Smith, E. M., Dorsey, S. G., Aaronson, N. K., Sloan, J. A., Loprinzi, C. L. & Beutler, A. S., Jun 20 2017, (Accepted/In press) In : Supportive Care in Cancer. p. 1-8 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Pig lumbar spine anatomy and imaging-guided lateral lumbar puncture: A new large animal model for intrathecal drug delivery

Pleticha, J., Maus, T., Jeng-Singh, C., Marsh, M. P., Al-Saiegh, F., Christner, J. A., Lee, K. H. & Beutler, A. S., May 2013, In : Journal of Neuroscience Methods. 216, 1, p. 10-15 6 p.

Research output: Contribution to journalArticle

17 Scopus citations
27 Scopus citations

Plasticity of DNA methylation in a nerve injury model of pain

Gölzenleuchter, M., Kanwar, R., Zaibak, M., Al Saiegh, F., Hartung, T., Klukas, J., Smalley, R. L., Cunningham, J. M., Figueroa, M. E., Schroth, G. P., Therneau, T. M., Banck, M. S. & Beutler, A. S., Jan 26 2015, In : Epigenetics. 10, 3, p. 200-212 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

Preclinical toxicity evaluation of AAV for pain: Evidence from human AAV studies and from the pharmacology of analgesic drugs

Pleticha, J., Heilmann, L. F., Evans, C. H., Asokan, A., Samulski, R. J. & Beutler, A. S., 2014, In : Molecular Pain. 10, 1, Article 54.

Research output: Contribution to journalArticle

11 Scopus citations

Randomized controlled trial of cryotherapy to prevent paclitaxel-induced peripheral neuropathy (RU221511I); an ACCRU trial

Ruddy, K. J., Le-Rademacher, J., Lacouture, M. E., Wilkinson, M., Onitilo, A. A., Vander Woude, A. C., Grosse-Perdekamp, M. T., Dockter, T., Tan, A. D., Beutler, A. & Loprinzi, C. L., Dec 2019, In : Breast. 48, p. 89-97 9 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Retrovirus-mediated expression of an artificial β-endorphin precursor in primary fibroblasts

Beutler, A. S., Banck, M. S., Bach, F. W., Gage, F. H., Porreca, F., Bilsky, E. J. & Yaksh, T. L., 1995, In : Journal of Neurochemistry. 64, 2, p. 475-481 7 p.

Research output: Contribution to journalArticle

24 Scopus citations
6 Scopus citations

Scrambler therapy for chemotherapy neuropathy: a randomized phase II pilot trial

Loprinzi, C., Le-Rademacher, J. G., Majithia, N., McMurray, R. P., O’Neill, C. R., Bendel, M. A., Beutler, A., Lachance, D. H., Cheville, A., Strick, D. M., Black, D. F., Tilburt, J. C. & Smith, T. J., Jan 1 2019, In : Supportive Care in Cancer.

Research output: Contribution to journalArticle

24 Scopus citations

Sensory neuron targeting by self-complementary AAV8 via lumbar puncture for chronic pain

Storek, B., Reinhardt, M., Wang, C., Janssen, W. G. M., Harder, N. M., Banck, M. S., Morrison, J. H. & Beutler, A. S., Jan 22 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 3, p. 1055-1060 6 p.

Research output: Contribution to journalArticle

100 Scopus citations

Sequencing of charcot-marie-tooth disease genes in a toxic polyneuropathy

Beutler, A. S., Kulkarni, A. A., Kanwar, R., Klein, C. J., Therneau, T. M., Qin, R., Banck, M. S., Boora, G. K., Ruddy, K. J., Wu, Y., Smalley, R. L., Cunningham, J. M., Le-Lindqwister, N. A., Beyerlein, P., Schroth, G. P., Windebank, A. J., Züchner, S. & Loprinzi, C. L., Nov 1 2014, In : Annals of Neurology. 76, 5, p. 727-737 11 p.

Research output: Contribution to journalArticle

47 Scopus citations
50 Scopus citations

Somatic mutation of CDKN1B in small intestine neuroendocrine tumors

Francis, J. M., Kiezun, A., Ramos, A. H., Serra, S., Pedamallu, C. S., Qian, Z. R., Banck, M. S., Kanwar, R., Kulkarni, A. A., Karpathakis, A., Manzo, V., Contractor, T., Philips, J., Nickerson, E., Pho, N., Hooshmand, S. M., Brais, L. K., Lawrence, M. S., Pugh, T., McKenna, A. & 27 others, Sivachenko, A., Cibulskis, K., Carter, S. L., Ojesina, A. I., Freeman, S., Jones, R. T., Voet, D., Saksena, G., Auclair, D., Onofrio, R., Shefler, E., Sougnez, C., Grimsby, J., Green, L., Lennon, N., Meyer, T., Caplin, M., Chung, D. C., Beutler, A. S., Ogino, S., Thirlwell, C., Shivdasani, R., Asa, S. L., Harris, C. R., Getz, G., Kulke, M. & Meyerson, M., Dec 2013, In : Nature Genetics. 45, 12, p. 1483-1486 4 p.

Research output: Contribution to journalArticle

140 Scopus citations