• 53069 Citations
  • 105 Scopus h-Index
1974 …2020

Research output per year

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Research Output

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Review article
2020

Application of the fourth universal definition of myocardial infarction in clinical practice

on behalf of the the European Society of Cardiology (ESC) Study Group on Biomarkers in Cardiology of the Acute Cardiovascular Care Association (ACVA), May 18 2020, In : Biomarkers. 25, 4, p. 322-330 9 p.

Research output: Contribution to journalReview article

Myocardial injury in severe COVID-19 infection

Jaffe, A. S., Cleland, J. G. F. & Katus, H. A., Jun 7 2020, In : European heart journal. 41, 22, p. 2080-2082 3 p.

Research output: Contribution to journalReview article

Open Access
2 Scopus citations
2019

Clinical use of cardiac troponin for acute cardiac care and emerging opportunities in the outpatient setting

Sandoval, Y., Sharain, K., Saenger, A. K., Smith, S. W., Apple, F. S. & Jaffe, A. S., Apr 1 2019, In : Minerva Medica. 110, 2, p. 139-156 18 p.

Research output: Contribution to journalReview article

1 Scopus citations

Recommendations for Institutions Transitioning to High-Sensitivity Troponin Testing: JACC Scientific Expert Panel

Januzzi, J. L., Mahler, S. A., Christenson, R. H., Rymer, J., Newby, L. K., Body, R., Morrow, D. A. & Jaffe, A. S., Mar 12 2019, In : Journal of the American College of Cardiology. 73, 9, p. 1059-1077 19 p.

Research output: Contribution to journalReview article

14 Scopus citations

Should myocardial infarction type 2 be regarded as two separate entities?

Thygesen, K. & Jaffe, A. S., Jan 1 2019, In : European heart journal. 40, 33, p. 2810-2812 3 p.

Research output: Contribution to journalReview article

2 Scopus citations

Type 2 Myocardial Infarction: JACC Review Topic of the Week

Sandoval, Y. & Jaffe, A. S., Apr 16 2019, In : Journal of the American College of Cardiology. 73, 14, p. 1846-1860 15 p.

Research output: Contribution to journalReview article

22 Scopus citations
2018

How is cardiac troponin released from injured myocardium?

Mair, J., Lindahl, B., Hammarsten, O., Müller, C., Giannitsis, E., Huber, K., Möckel, M., Plebani, M., Thygesen, K. & Jaffe, A. S., Sep 1 2018, In : European heart journal. Acute cardiovascular care. 7, 6, p. 553-560 8 p.

Research output: Contribution to journalReview article

40 Scopus citations

Possible mechanisms behind cardiac troponin elevations

Hammarsten, O., Mair, J., Möckel, M., Lindahl, B. & Jaffe, A. S., Nov 17 2018, In : Biomarkers. 23, 8, p. 725-734 10 p.

Research output: Contribution to journalReview article

15 Scopus citations

Use of copeptin for rapid rule-out of acute myocardial infarction

ESC Study Group on Biomarkers in Cardiology of the Acute Cardiovascular Care Association, Sep 1 2018, In : European heart journal. Acute cardiovascular care. 7, 6, p. 570-576 7 p.

Research output: Contribution to journalReview article

15 Scopus citations
2017

Cardiac troponin assays: Guide to understanding analytical characteristics and their impact on clinical care

Apple, F. S., Sandoval, Y., Jaffe, A. S. & Ordonez-Llanos, J., Jan 2017, In : Clinical chemistry. 63, 1, p. 73-81 9 p.

Research output: Contribution to journalReview article

124 Scopus citations

High-Sensitivity Cardiac Troponin for the Diagnosis of Patients with Acute Coronary Syndromes

Vasile, V. C. & Jaffe, A. S., Oct 1 2017, In : Current Cardiology Reports. 19, 10, 92.

Research output: Contribution to journalReview article

8 Scopus citations

How to use D-dimer in acute cardiovascular care

Biomarker Study Group of the European Society of Cardiology (ESC) Acute Cardiovascular Care Association (ACCA), Feb 1 2017, In : European heart journal. Acute cardiovascular care. 6, 1, p. 69-80 12 p.

Research output: Contribution to journalReview article

21 Scopus citations

Lipid Biomarkers for Risk Assessment in Acute Coronary Syndromes

Meeusen, J. W., Donato, L. J. & Jaffe, A. S., Jun 1 2017, In : Current Cardiology Reports. 19, 6, 48.

Research output: Contribution to journalReview article

4 Scopus citations

Natriuretic peptides and analytical barriers

Vasile, V. C. & Jaffe, A. S., Jan 2017, In : Clinical chemistry. 63, 1, p. 50-58 9 p.

Research output: Contribution to journalReview article

21 Scopus citations

Rapid rule out of acute myocardial infarction: novel biomarker-based strategies

Biomarker Study Group of the ESC Acute Cardiovascular Care Association, Apr 1 2017, In : European heart journal. Acute cardiovascular care. 6, 3, p. 218-222 5 p.

Research output: Contribution to journalReview article

29 Scopus citations

Rapid rule-out of acute myocardial infarction with a single high-sensitivity cardiac troponin t measurement below the limit of detection: A collaborative meta-analysis

Pickering, J. W., Than, M. P., Cullen, L., Aldous, S., Ter Avest, E., Body, R., Carlton, E. W., Collinson, P., Dupuy, A. M., Ekelund, U., Eggers, K. M., Florkowski, C. M., Freund, Y., George, P., Goodacre, S., Greenslade, J. H., Jaffe, A. S., Lord, S. J., Mokhtari, A., Mueller, C. & 12 others, Munro, A., Mustapha, S., Parsonage, W., Peacock, W. F., Pemberton, C., Richards, A. M., Sanchis, J., Staub, L. P., Troughton, R., Twerenbold, R., Wildi, K. & Young, J., May 16 2017, In : Annals of internal medicine. 166, 10, p. 715-724 10 p.

Research output: Contribution to journalReview article

103 Scopus citations

Renal Dysfunction: How to Think About That in Acute Coronary Syndromes

Babuin, L., Scarpa, D. & Jaffe, A. S., Oct 1 2017, In : Current Cardiology Reports. 19, 10, 91.

Research output: Contribution to journalReview article

1 Scopus citations
2016

Biomarkers in heart failure: the importance of inconvenient details

Miller, W. & Jaffe, A. S., Jan 1 2016, In : ESC heart failure. 3, 1, p. 3-10 8 p.

Research output: Contribution to journalReview article

10 Scopus citations

Improving Survival From Cardiac Arrest: A Review of Contemporary Practice and Challenges

Jentzer, J. C., Clements, C. M., Wright, R. S., White, R. D. & Jaffe, A. S., Dec 1 2016, In : Annals of Emergency Medicine. 68, 6, p. 678-689 12 p.

Research output: Contribution to journalReview article

21 Scopus citations

Should apolipoprotein B replace LDL cholesterol as therapeutic targets are lowered?

Meeusen, J. W., Donato, L. J. & Jaffe, A. S., Aug 1 2016, In : Current Opinion in Lipidology. 27, 4, p. 359-366 8 p.

Research output: Contribution to journalReview article

5 Scopus citations
2015

Comparison of conventional and high-sensitivity troponin in patients with chest pain: A collaborative meta-analysis

Lipinski, M. J., Baker, N. C., Escárcega, R. O., Torguson, R., Chen, F., Aldous, S. J., Christ, M., Collinson, P. O., Goodacre, S. W., Mair, J., Inoue, K., Lotze, U., Sebbane, M., Cristol, J. P., Freund, Y., Chenevier-Gobeaux, C., Meune, C., Eggers, K. M., Pracoń, R., Schreiber, D. H. & 6 others, Wu, A. H. B., Ordõez-Llanos, J., Jaffe, A. S., Twerenbold, R., Mueller, C. & Waksman, R., Jan 2015, In : American heart journal. 169, 1, p. 6-16.e6

Research output: Contribution to journalReview article

46 Scopus citations

Fundamental concepts of effective troponin use: Important principles for internists

Sara, J. D. S., Holmes, D. R. & Jaffe, A. S., Feb 1 2015, In : American Journal of Medicine. 128, 2, p. 111-119 9 p.

Research output: Contribution to journalReview article

13 Scopus citations

Soluble ST2 - Analytical considerations

Mueller, T. & Jaffe, A. S., Apr 2 2015, In : American Journal of Cardiology. 115, 7, p. 8B-21B

Research output: Contribution to journalReview article

41 Scopus citations

Unraveling N-terminal pro-B-type natriuretic peptide: Another piece to a very complex puzzle in heart failure patients

Jaffe, A. S., Apple, F. S., Mebazaa, A. & Vodovar, N., Aug 1 2015, In : Clinical chemistry. 61, 8, p. 1016-1018 3 p.

Research output: Contribution to journalReview article

13 Scopus citations
2014

2014 AHA/ACC guideline for the management of patients with non-st-elevation acute coronary syndromes: A report of the American college of cardiology/American heart association task force on practice guidelines

Writing Committee Members ACC/AHA Task Force Members, Dec 23 2014, In : Circulation. 130, 25, p. e344-e426

Research output: Contribution to journalReview article

587 Scopus citations

Depression as a risk factor for poor prognosis among patients with acute coronary syndrome: Systematic review and recommendations: A scientific statement from the american heart association

Lichtman, J. H., Froelicher, E. S., Blumenthal, J. A., Carney, R. M., Doering, L. V., Frasure-Smith, N., Freedland, K. E., Jaffe, A. S., Leifheit-Limson, E. C., Sheps, D. S., Vaccarino, V. & Wulsin, L., Mar 25 2014, In : Circulation. 129, 12, p. 1350-1369 20 p.

Research output: Contribution to journalReview article

498 Scopus citations

Diagnostic and therapeutic implications of type 2 myocardial infarction: Review and commentary

Alpert, J. S., Thygesen, K. A., White, H. D. & Jaffe, A. S., Feb 1 2014, In : American Journal of Medicine. 127, 2, p. 105-108 4 p.

Research output: Contribution to journalReview article

80 Scopus citations

Emerging biomarkers for acute heart conditions

Vasile, V. C. & Jaffe, A. S., Jul 2014, In : Current opinion in cardiology. 29, 4, p. 312-318 7 p.

Research output: Contribution to journalReview article

11 Scopus citations

High-sensitivity troponin: Where are we now and where do we go from here?

Korley, F. K. & Jaffe, A. S., Aug 1 2014, In : Biomarkers in Medicine. 8, 8, p. 1021-1032 12 p.

Research output: Contribution to journalReview article

2 Scopus citations

Improving the 510(k) FDA process for cardiac troponin assays: In search of common ground

Apple, F. S., Hollander, J., Wu, A. H. B. & Jaffe, A. S., Oct 1 2014, In : Clinical chemistry. 60, 10, p. 1273-1275 3 p.

Research output: Contribution to journalReview article

14 Scopus citations

Universal MI definition update for cardiovascular disease

White, H., Thygesen, K., Alpert, J. S. & Jaffe, A., Jun 2014, In : Current cardiology reports. 16, 6, 492.

Research output: Contribution to journalReview article

25 Scopus citations
2013

Elevated cardiac troponin T levels in critically ill patients with sepsis

Vasile, V. C., Chai, H. S., Abdeldayem, D., Afessa, B. & Jaffe, A. S., Dec 1 2013, In : American Journal of Medicine. 126, 12, p. 1114-1121 8 p.

Research output: Contribution to journalReview article

43 Scopus citations

Preparing the United States for high-sensitivity cardiac troponin assays

Korley, F. K. & Jaffe, A. S., Apr 30 2013, In : Journal of the American College of Cardiology. 61, 17, p. 1753-1758 6 p.

Research output: Contribution to journalReview article

112 Scopus citations
2012

High-sensitive troponin T measurements: What do we gain and what are the challenges?

Twerenbold, R., Jaffe, A., Reichlin, T., Reiter, M. & Mueller, C., Mar 1 2012, In : European heart journal. 33, 5, p. 579-586 8 p.

Research output: Contribution to journalReview article

141 Scopus citations

Recommendations for the use of natriuretic peptides in acute cardiac care: A position statement from the Study Group on Biomarkers in Cardiology of the ESC Working Group on Acute Cardiac Care

Thygesen, K., Mair, J., Mueller, C., Huber, K., Weber, M., Plebani, M., Hasin, Y., Biasucci, L. M., Giannitsis, E., Lindahl, B., Koenig, W., Tubaro, M., Collinson, P., Katus, H., Galvani, M., Venge, P., Alpert, J. S., Hamm, C. & Jaffe, A. S., Aug 1 2012, In : European heart journal. 33, 16, p. 2001-2006 6 p.

Research output: Contribution to journalReview article

165 Scopus citations

Third universal definition of myocardial infarction

Thygesen, K., Alpert, J. S., Jaffe, A. S., Simoons, M. L., Chaitman, B. R. & White, H. D., Nov 1 2012, In : Nature Reviews Cardiology. 9, 11, p. 620-633 14 p.

Research output: Contribution to journalReview article

115 Scopus citations

Thirty-day rehospitalizations after acute myocardial infarction: A cohort study

Dunlay, S. M., Weston, S. A., Killian, J. M., Bell, M. R., Jaffe, A. S. & Roger, V. L., Jan 1 2012, In : Annals of internal medicine. 157, 1, p. 11-18 8 p.

Research output: Contribution to journalReview article

73 Scopus citations
2011

The 10 commandments of troponin, with special reference to high sensitivity assays

Jaffe, A. S., Jun 1 2011, In : Heart. 97, 11, p. 940-946 7 p.

Research output: Contribution to journalReview article

53 Scopus citations

The clinical impact of circulating caspase-3 p17 level: A potential new biomarker for myocardial injury and cardiovascular disease

Singh, K. P., Jaffe, A. S. & Liang, B. T., Jul 1 2011, In : Future Cardiology. 7, 4, p. 443-445 3 p.

Research output: Contribution to journalReview article

3 Scopus citations
2010

Comprehensive standardized data definitions for acute coronary syndrome research in emergency departments in Australasia: Special Report

Cullen, L., Than, M., Brown, A. F., Richards, M., Parsonage, W., Flaws, D., Hollander, J. E., Christenson, R. H., Kline, J. A., Goodacre, S. & Jaffe, A. S., Feb 1 2010, In : EMA - Emergency Medicine Australasia. 22, 1, p. 35-55 21 p.

Research output: Contribution to journalReview article

83 Scopus citations

Identification of myocardial injury in the emergency setting

Kavsak, P. A., Worster, A., You, J. J., Oremus, M., Elsharif, A., Hill, S. A., Devereaux, P. J., MacRae, A. R. & Jaffe, A. S., Apr 1 2010, In : Clinical Biochemistry. 43, 6, p. 539-544 6 p.

Research output: Contribution to journalReview article

6 Scopus citations

Recommendations for the use of cardiac troponin measurement in acute cardiac care

Thygesen, K., Mair, J., Katus, H., Plebani, M., Venge, P., Collinson, P., Lindahl, B., Giannitsis, E., Hasin, Y., Galvani, M., Tubaro, M., Alpert, J. S., Biasucci, L. M., Koenig, W., Mueller, C., Huber, K., Hamm, C. & Jaffe, A. S., Sep 1 2010, In : European heart journal. 31, 18, p. 2197-2204 8 p.

Research output: Contribution to journalReview article

443 Scopus citations
2009

Aborted myocardial infarction: Is it real in the troponin era?

Vasile, V. C., Babuin, L., Ting, H. H., Bell, M. R., Orme, N. M., Yuan, B. Y., Perez, J. A. R., Alegria, J. R., Bellolio, F., Haro, L. H. & Jaffe, A. S., Apr 2009, In : American Heart Journal. 157, 4, p. 636-641 6 p.

Research output: Contribution to journalReview article

8 Scopus citations

Ethical issues in cardiovascular research involving humans

Frye, R. L., Simari, R. D., Gersh, B. J., Burnett, J. C., Brumm, S., Myerle, K., Jaffe, A. S., Holmes, D. R., Lerman, A. & Terzic, A., Nov 1 2009, In : Circulation. 120, 21, p. 2113-2121 9 p.

Research output: Contribution to journalReview article

5 Scopus citations

Perioperative myocardial infarction

Landesberg, G., Beattie, W. S., Mosseri, M., Jaffe, A. S. & Alpert, J. S., Jun 9 2009, In : Circulation. 119, 22, p. 2936-2944 9 p.

Research output: Contribution to journalReview article

277 Scopus citations

The biological basis of troponin in heart disease: Possible uses for troponin fragmentology

Vasile, V. C. & Jaffe, A. S., Sep 28 2009, In : Heart and Metabolism. 43, p. 5-8 4 p.

Research output: Contribution to journalReview article

5 Scopus citations

The spin stops here: Inhibition of lipoprotein-associated phospholipase A2 - A promising target but a negative initial trial?

McConnell, J. P. & Jaffe, A. S., Jan 1 2009, In : Clinical chemistry. 55, 1, p. 21-23 3 p.

Research output: Contribution to journalReview article

4 Scopus citations
2008

Diagnostic accuracy of clinical prediction rules to exclude acute coronary syndrome in the emergency department setting: A systematic review

Hess, E. P., Thiruganasambandamoorthy, V., Wells, G. A., Erwin, P., Jaffe, A. S., Hollander, J. E., Montori, V. M. & Stiell, I. G., Jul 2008, In : Canadian Journal of Emergency Medicine. 10, 4, p. 373-382 10 p.

Research output: Contribution to journalReview article

Open Access
53 Scopus citations

Diagnostic application of the universal definition of myocardial infarction in the intensive care unit

Thygesen, K., Alpert, J. S., Jaffe, A. S. & White, H. D., Oct 1 2008, In : Current Opinion in Critical Care. 14, 5, p. 543-548 6 p.

Research output: Contribution to journalReview article

30 Scopus citations