Alexandre Gaspar Maia, PhD

  • 1292 Citations
  • 12 Scopus h-Index
20062018
If you made any changes in Pure, your changes will be visible here soon.

Research Output 2006 2018

  • 1292 Citations
  • 12 Scopus h-Index
  • 11 Article
  • 3 Review article
  • 2 Comment/debate
  • 1 Chapter
2018
3 Citations (Scopus)

Transcription-associated histone pruning demarcates macroH2A chromatin domains

Sun, Z., Filipescu, D., Andrade, J., Gaspar Maia, A., Ueberheide, B. & Bernstein, E., Oct 1 2018, In : Nature Structural and Molecular Biology. 25, 10, p. 958-970 13 p.

Research output: Contribution to journalArticle

Histones
Chromatin
Genome
Transcriptional Activation
Protein Isoforms
2016
32 Citations (Scopus)

Cbx8 Acts Non-canonically with Wdr5 to Promote Mammary Tumorigenesis

Chung, C. Y., Sun, Z., Mullokandov, G., Bosch, A., Qadeer, Z. A., Cihan, E., Rapp, Z., Parsons, R., Aguirre-Ghiso, J. A., Farias, E. F., Brown, B. D., Gaspar Maia, A. & Bernstein, E., Jul 12 2016, In : Cell Reports. 16, 2, p. 472-486 15 p.

Research output: Contribution to journalArticle

Methyltransferases
Gene expression
Chromatin
Carcinogenesis
Breast

Chromatin Dynamics and Epigenetics of Stem Cells and Stem-Like Cancer Cells

Gaspar Maia, A. & Sevilla, A., Aug 24 2016, Chromatin Signaling and Diseases. Elsevier Inc., p. 311-327 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Neoplastic Stem Cells
Stem cells
Epigenomics
Chromatin
Stem Cells
2015
70 Citations (Scopus)

Histone Variant H2A.Z.2 Mediates Proliferation and Drug Sensitivity of Malignant Melanoma

Vardabasso, C., Gaspar Maia, A., Hasson, D., Pünzeler, S., Valle-Garcia, D., Straub, T., Keilhauer, E. C., Strub, T., Dong, J., Panda, T., Chung, C. Y., Yao, J. L., Singh, R., Segura, M. F., Fontanals-Cirera, B., Verma, A., Mann, M., Hernando, E., Hake, S. B. & Bernstein, E., Jan 1 2015, In : Molecular Cell. 59, 1, p. 75-88 14 p.

Research output: Contribution to journalArticle

Histones
Melanoma
Pharmaceutical Preparations
Cell Proliferation
Genes
77 Citations (Scopus)

NR2F1 controls tumour cell dormancy via SOX9- and RARβ-driven quiescence programmes

Sosa, M. S., Parikh, F., Gaspar Maia, A., Estrada, Y., Bosch, A., Bragado, P., Ekpin, E., George, A., Zheng, Y., Lam, H. M., Morrissey, C., Chung, C. Y., Farias, E. F., Bernstein, E. & Aguirre-Ghiso, J. A., Jan 30 2015, In : Nature Communications. 6, 7170.

Research output: Contribution to journalArticle

Tumors
tumors
Cells
cancer
Neoplasms
2013

Erratum: MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency (Nature Communications (2013) 4, (1565) DOI: 10.1038/ncomms2582)

Gaspar Maia, A., Qadeer, Z. A., Hasson, D., Ratnakumar, K., Leu, N. A., Leroy, G., Liu, S., Costanzi, C., Valle-Garcia, D., Schaniel, C., Lemischka, I., Garcia, B., Pehrson, J. R. & Bernstein, E., Jan 1 2013, In : Nature Communications. 4, 2090.

Research output: Contribution to journalComment/debate

Communication
macroH2A histone
108 Citations (Scopus)

MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency

Gaspar Maia, A., Qadeer, Z. A., Hasson, D., Ratnakumar, K., Adrian Leu, N., Leroy, G., Liu, S., Costanzi, C., Valle-Garcia, D., Schaniel, C., Lemischka, I., Garcia, B., Pehrson, J. R. & Bernstein, E., Apr 11 2013, In : Nature Communications. 4, 1565.

Research output: Contribution to journalArticle

Protein Isoforms
Genes
genes
Fibroblasts
Epigenomics
2012
130 Citations (Scopus)

MicroRNA regulation of Cbx7 mediates a switch of polycomb orthologs during ESC differentiation

O'Loghlen, A., Muñoz-Cabello, A. M., Gaspar Maia, A., Wu, H. A., Banito, A., Kunowska, N., Racek, T., Pemberton, H. N., Beolchi, P., Lavial, F., Masui, O., Vermeulen, M., Carroll, T., Graumann, J., Heard, E., Dillon, N., Azuara, V., Snijders, A. P., Peters, G., Bernstein, E. & 1 others, Gil, J., Jan 6 2012, In : Cell Stem Cell. 10, 1, p. 33-46 14 p.

Research output: Contribution to journalArticle

Embryonic Stem Cells
MicroRNAs
Cell Differentiation
Polycomb Repressive Complex 1
X Chromosome Inactivation
2011

Erratum: Open chromatin in pluripotency and reprogramming (Nature Reviews Molecular Cell Biology (2011) 12 (36-47))

Gaspar Maia, A., Alajem, A., Meshorer, E. & Ramalho-Santos, M., Apr 1 2011, In : Nature Reviews Molecular Cell Biology. 12, 4, 1 p.

Research output: Contribution to journalComment/debate

Chromatin
Cell Biology
Molecular Biology
310 Citations (Scopus)

Open chromatin in pluripotency and reprogramming

Gaspar Maia, A., Alajem, A., Meshorer, E. & Ramalho-Santos, M., Jan 1 2011, In : Nature Reviews Molecular Cell Biology. 12, 1, p. 36-47 12 p.

Research output: Contribution to journalReview article

Chromatin
Pluripotent Stem Cells
Transcriptional Activation
Stem Cells
Embryonic Structures
40 Citations (Scopus)

Stem cells and reprogramming: Breaking the epigenetic barrier?

Ang, Y. S., Gaspar Maia, A., Lemischka, I. R. & Bernstein, E., Jul 1 2011, In : Trends in Pharmacological Sciences. 32, 7, p. 394-401 8 p.

Research output: Contribution to journalReview article

Embryonic Stem Cells
Stem cells
Epigenomics
Histones
Stem Cells
2009
339 Citations (Scopus)

Chd1 regulates open chromatin and pluripotency of embryonic stem cells

Gaspar Maia, A., Alajem, A., Polesso, F., Sridharan, R., Mason, M. J., Heidersbach, A., Ramalho-Santos, J., McManus, M. T., Plath, K., Meshorer, E. & Ramalho-Santos, M., Aug 13 2009, In : Nature. 460, 7257, p. 863-868 6 p.

Research output: Contribution to journalArticle

Embryonic Stem Cells
Chromatin
Heterochromatin
Stem Cells
Euchromatin
2008
47 Citations (Scopus)

High-efficiency stem cell fusion-mediated assay reveals Sall4 as an enhancer of reprogramming

Wong, C. C., Gaspar Maia, A., Ramalho-Santos, M. & Reijo Pera, R. A., Apr 16 2008, In : PLoS One. 3, 4, e1955.

Research output: Contribution to journalArticle

cell fusion
Cell Fusion
embryonic stem cells
Embryonic Stem Cells
Stem cells
2007
43 Citations (Scopus)

Is there a plastid in Perkinsus atlanticus (Phylum Perkinsozoa)?

Leonor Teles-Grilo, M., Tato-Costa, J., Duarte, S. M., Gaspar Maia, A., Casal, G. & Azevedo, C., Jul 2 2007, In : European Journal of Protistology. 43, 2, p. 163-167 5 p.

Research output: Contribution to journalArticle

Plastids
Apicomplexa
Alveolata
Plastid Genomes
Dinoflagellida
8 Citations (Scopus)

Molecular karyotype analysis of Perkinsus atlanticus (Phylum Perkinsozoa) by pulsed field gel electrophoresis

Leonor Teles-Grilo, M., Duarte, S. M., Tato-Costa, J., Gaspar Maia, A., Oliveira, C., Rocha, A. A., Marques, A., Cordeiro-da-Silva, A. & Azevedo, C., Nov 5 2007, In : European Journal of Protistology. 43, 4, p. 315-318 4 p.

Research output: Contribution to journalArticle

Dinoflagellida
Pulsed Field Gel Electrophoresis
Karyotype
Alveolata
Chromosomes
68 Citations (Scopus)

Systematic identification of cis-regulatory sequences active in mouse and human embryonic stem cells

Grskovic, M., Chaivorapol, C., Gaspar Maia, A., Li, H. & Ramalho-Santos, M., Aug 1 2007, In : PLoS Genetics. 3, 8, p. 1524-1540 17 p.

Research output: Contribution to journalArticle

regulatory sequences
embryonic stem cells
stem
Embryonic Stem Cells
germ cell
2006
17 Citations (Scopus)

RNA interference in embryonic stem cells and the prospects for future therapies

Heidersbach, A., Gaspar Maia, A., McManus, M. T. & Ramalho-Santos, M., Mar 1 2006, In : Gene Therapy. 13, 6, p. 478-486 9 p.

Research output: Contribution to journalReview article

Embryonic Stem Cells
RNA Interference
Biomedical Research
Research Personnel
Therapeutics