• 19640 Citations
  • 72 Scopus h-Index
1976 …2020

Research output per year

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Research Output

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Review article
2020

Immune Checkpoint Inhibitors in Thoracic Malignancies: Review of the Existing Evidence by an IASLC Expert Panel and Recommendations

Remon, J., Passiglia, F., Ahn, M. J., Barlesi, F., Forde, P. M., Garon, E. B., Gettinger, S., Goldberg, S. B., Herbst, R. S., Horn, L., Kubota, K., Lu, S., Mezquita, L., Paz-Ares, L., Popat, S., Schalper, K. A., Skoulidis, F., Reck, M., Adjei, A. A. & Scagliotti, G. V., Jan 1 2020, (Accepted/In press) In : Journal of Thoracic Oncology.

Research output: Contribution to journalReview article

1 Scopus citations
2019

Antibody-Drug Conjugates for the Therapy of Thoracic Malignancies

Xie, H. & Adjei, A. A., Mar 2019, In : Journal of Thoracic Oncology. 14, 3, p. 358-376 19 p.

Research output: Contribution to journalReview article

2 Scopus citations

A Proposed System Toward Standardizing Surgical-Based Treatments for Malignant Pleural Mesothelioma, From the Joint National Cancer Institute–International Association for the Study of Lung Cancer–Mesothelioma Applied Research Foundation Taskforce

Friedberg, J. S., Culligan, M. J., Tsao, A. S., Rusch, V., Sepesi, B., Pass, H. I., Bueno, R., Burt, B., Sugarbaker, D. J., de Perrot, M., Adjei, A., Adusumilli, P. S., Hirsch, F. R., Malik, S. M. & Harpole, D. J., Aug 1 2019, In : Journal of Thoracic Oncology. 14, 8, p. 1343-1353 11 p.

Research output: Contribution to journalReview article

5 Scopus citations

Characterization of Comorbidities Limiting the Recruitment of Patients in Early Phase Clinical Trials

Duma, N., Kothadia, S. M., Azam, T. U., Yadav, S., Paludo, J., Vera Aguilera, J., Gonzalez Velez, M., Halfdanarson, T. R., Molina, J. R., Hubbard, J. M., Go, R. S., Mansfield, A. S. & Adjei, A. A., Jan 2019, In : Oncologist. 24, 1, p. 96-102 7 p.

Research output: Contribution to journalReview article

2 Scopus citations

Control of confounding and reporting of results in causal inference studies

Lederer, D. J., Bell, S. C., Branson, R. D., Chalmers, J. D., Marshall, R., Maslove, D. M., Ost, D. E., Punjabi, N. M., Schatz, M., Smyth, A. R., Stewart, P. W., Suissa, S., Adjei, A. A., Akdis, C. A., Azoulay, É., Bakker, J., Ballas, Z. K., Bardin, P. G., Barreiro, E., Bellomo, R. & 28 others, Bernstein, J. A., Brusasco, V., Buchman, T. G., Chokroverty, S., Collop, N. A., Crapo, J. D., Fitzgerald, D. A., Hale, L., Hart, N., Herth, F. J., Iwashyna, T. J., Jenkins, G., Kolb, M., Marks, G. B., Mazzone, P., Moorman, J. R., Murphy, T. M., Noah, T. L., Reynolds, P., Riemann, D., Russell, R. E., Sheikh, A., Sotgiu, G., Swenson, E. R., Szczesniak, R., Szymusiak, R., Teboul, J. L. & Vincent, J. L., Jan 2019, In : Annals of the American Thoracic Society. 16, 1, p. 22-28 7 p.

Research output: Contribution to journalReview article

92 Scopus citations

Current Diagnosis and Management of Small-Cell Lung Cancer

Wang, S., Zimmermann, S., Parikh, K., Mansfield, A. S. & Adjei, A. A., Aug 2019, In : Mayo Clinic proceedings. 94, 8, p. 1599-1622 24 p.

Research output: Contribution to journalReview article

Open Access
5 Scopus citations

The Use of Radiation Therapy for the Treatment of Malignant Pleural Mesothelioma: Expert Opinion from the National Cancer Institute Thoracic Malignancy Steering Committee, International Association for the Study of Lung Cancer, and Mesothelioma Applied Research Foundation

Gomez, D. R., Rimner, A., Simone, C. B., Cho, B. C. J., de Perrot, M., Adjei, A., Bueno, R., Gill, R. R., Harpole, D. H., Hesdorffer, M., Hirsch, F. R., Jackson, A. A., Pass, H. I., Rice, D. C., Rusch, V. W., Tsao, A. S., Yorke, E. & Rosenzweig, K., Jul 1 2019, In : Journal of Thoracic Oncology. 14, 7, p. 1172-1183 12 p.

Research output: Contribution to journalReview article

Open Access
5 Scopus citations
2018

Biomarker Clinical Trials in Lung Cancer: Design, Logistics, Challenges, and Practical Considerations

Le-Rademacher, J., Dahlberg, S., Lee, J. J., Adjei, A. & Mandrekar, S. J., Nov 1 2018, In : Journal of Thoracic Oncology. 13, 11, p. 1625-1637 13 p.

Research output: Contribution to journalReview article

2 Scopus citations

Representation of minorities and women in oncology clinical trials: Review of the past 14 years

Duma, N., Aguilera, J. V., Paludo, J., Haddox, C. L., Velez, M. G., Wang, Y., Leventakos, K., Hubbard, J. M., Mansfield, A., Go, R. S. & Adjei, A., Jan 1 2018, In : Journal of Oncology Practice. 14, 1, p. e1-e10

Research output: Contribution to journalReview article

22 Scopus citations
2016

FGFR signaling as a target for Lung cancer therapy

Desai, A. & Adjei, A., Jan 1 2016, In : Journal of Thoracic Oncology. 11, 1, p. 9-20 12 p.

Research output: Contribution to journalReview article

31 Scopus citations

Novel active agents in patients with advanced NSCLC without driver mutations who have progressed after first-line chemotherapy

Manegold, C., Adjei, A., Bussolino, F., Cappuzzo, F., Crino, L., Dziadziuszko, R., Ettinger, D., Fennell, D., Kerr, K., Le Chevalier, T., Leighl, N., Papotti, M., Paz-Ares, L., Pérol, M., Peters, S., Pirker, R., Quoix, E., Reck, M., Smit, E., Vokes, E. & 2 others, Van Zandwijk, N. & Zhou, C., Dec 1 2016, In : ESMO Open. 1, 6, e000118.

Research output: Contribution to journalReview article

4 Scopus citations
2015

BRAF alterations as therapeutic targets in non-small-cell lung cancer

Nguyen-Ngoc, T., Bouchaab, H., Adjei, A. & Peters, S., Oct 1 2015, In : Journal of Thoracic Oncology. 10, 10, p. 1396-1403 8 p.

Research output: Contribution to journalReview article

47 Scopus citations
2014

ALK inhibitors in the treatment of advanced NSCLC

Gridelli, C., Peters, S., Sgambato, A., Casaluce, F., Adjei, A. A. & Ciardiello, F., Mar 1 2014, In : Cancer Treatment Reviews. 40, 2, p. 300-306 7 p.

Research output: Contribution to journalReview article

119 Scopus citations

Crosstalk between hedgehog and other signaling pathways as a basis for combination therapies in cancer

Brechbiel, J., Miller-Moslin, K. & Adjei, A. A., Jul 2014, In : Cancer Treatment Reviews. 40, 6, p. 750-759 10 p.

Research output: Contribution to journalReview article

107 Scopus citations
91 Scopus citations

Targeting oncogenic drivers

Zhao, Y. & Adjei, A., Jan 1 2014, In : Progress in tumor research. 41, p. 1-14 14 p.

Research output: Contribution to journalReview article

6 Scopus citations

The clinical development of MEK inhibitors

Zhao, Y. & Adjei, A. A., Jul 2014, In : Nature Reviews Clinical Oncology. 11, 7, p. 385-400 16 p.

Research output: Contribution to journalReview article

210 Scopus citations
2013

Strategies for improving outcomes in NSCLC: A look to the future

Stahel, R., Peters, S., Baas, P., Brambilla, E., Cappuzzo, F., De Ruysscher, D., Eberhardt, W. E. E., Felip, E., Fennell, D., Marchetti, A., Paz-Ares, L. & Adjei, A. A., Dec 1 2013, In : Lung Cancer. 82, 3, p. 375-382 8 p.

Research output: Contribution to journalReview article

18 Scopus citations
2012

MET: A promising anticancer therapeutic target

Peters, S. & Adjei, A. A., Jun 1 2012, In : Nature Reviews Clinical Oncology. 9, 6, p. 314-326 13 p.

Research output: Contribution to journalReview article

213 Scopus citations
2011

In the clinic: Ongoing clinical trials evaluating c-MET-inhibiting drugs

Sharma, N. & Adjei, A., Jan 1 2011, In : Therapeutic Advances in Medical Oncology. 3, 1, p. S37-S50

Research output: Contribution to journalReview article

46 Scopus citations
2009

Cooperative group research efforts in thoracic malignancies 2009: A review from the 10th annual international lung cancer congress

Wakelee, H., Loo, B. W., Kernstine, K. H., Putnam, J. B., Edelman, M. J., Vokes, E. E., Schiller, J. H., Baas, P., Saijo, N., Adjei, A., Goss, G., Choy, H. & Gandara, D. R., 2009, In : Clinical Lung Cancer. 10, 6, p. 395-404 10 p.

Research output: Contribution to journalReview article

3 Scopus citations

Cooperative group research endeavors in small-cell lung cancer: Current and future directions

Sangha, R., Lara, P. N., Adjei, A. A., Baas, P., Choy, H., Gaspar, L. E., Goss, G., Saijo, N., Schiller, J. H., Vokes, E. E. & Gandara, D. R., 2009, In : Clinical lung cancer. 10, 5, p. 322-330 9 p.

Research output: Contribution to journalReview article

4 Scopus citations

Novel agents on the horizon for cancer therapy

Ma, W. W. & Adjei, A. A., Mar 1 2009, In : CA Cancer Journal for Clinicians. 59, 2, p. 111-137 27 p.

Research output: Contribution to journalReview article

270 Scopus citations
2008

Advances in targeting the Ras/Raf/MEK/Erk mitogen-activated protein kinase cascade with MEK inhibitors for cancer therapy

Friday, B. B. & Adjei, A. A., Jan 15 2008, In : Clinical Cancer Research. 14, 2, p. 342-346 5 p.

Research output: Contribution to journalReview article

280 Scopus citations

Cooperative group portfolio in locally advanced non-small-cell lung cancer: Are we making progress?

Langer, C. J., Wakelee, H., Schiller, J., Choy, H., Shepherd, F., Vokes, E. E., Adjei, A. A., Baas, P., Saijo, N. & Gandara, D. R., Mar 2008, In : Clinical lung cancer. 9, 2, p. 85-91 7 p.

Research output: Contribution to journalReview article

6 Scopus citations

Cooperative group research efforts in lung cancer: Focus on early-stage non-small-cell lung cancer

Wakelee, H., Langer, C., Vokes, E., Schiller, J., Baas, P., Saijo, N., Adjei, A., Shepherd, F., Choy, H. & Gandara, D. R., Jan 2008, In : Clinical lung cancer. 9, 1, p. 9-15 7 p.

Research output: Contribution to journalReview article

5 Scopus citations

Systemic cancer therapy: Evolution over the last 60 years

Dy, G. K. & Adjei, A. A., Oct 1 2008, In : Cancer. 113, 7, p. 1857-1887 31 p.

Research output: Contribution to journalReview article

44 Scopus citations
2007

Inhibitors of Raf kinase and MEK signaling

Ramnath, N. & Adjei, A., Sep 1 2007, In : Update on Cancer Therapeutics. 2, 3, p. 111-118 8 p.

Research output: Contribution to journalReview article

17 Scopus citations
2006

Farnesyltransferase inhibitors

Adjei, A. A., Mar 1 2006, In : Update on Cancer Therapeutics. 1, 1, p. 17-23 7 p.

Research output: Contribution to journalReview article

5 Scopus citations

The Akt/mTOR and mitogen-activated protein kinase pathways in lung cancer therapy

Papadimitrakopoulou, V. & Adjei, A. A., Sep 2006, In : Journal of Thoracic Oncology. 1, 7, p. 749-751 3 p.

Research output: Contribution to journalReview article

31 Scopus citations
2005

Farnesyltransferase inhibitors.

Adjei, A. A., 2005, In : Cancer chemotherapy and biological response modifiers. 22, p. 123-133 11 p.

Research output: Contribution to journalReview article

22 Scopus citations

Intracellular signal transduction pathway proteins as targets for cancer therapy

Adjei, A. A. & Hidalgo, M., Dec 1 2005, In : Journal of Clinical Oncology. 23, 23, p. 5386-5403 18 p.

Research output: Contribution to journalReview article

146 Scopus citations

K-ras as a target for cancer therapy

Friday, B. B. & Adjei, A. A., Nov 25 2005, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1756, 2, p. 127-144 18 p.

Research output: Contribution to journalReview article

182 Scopus citations

Obstacles and opportunities in the clinical development of targeted therapeutics

Dy, G. K. & Adjei, A. A., Oct 12 2005, In : Progress in Drug Research. 63, p. 19-41 23 p.

Research output: Contribution to journalReview article

8 Scopus citations

Sequencing bortezomib with chemotherapy and targeted agents.

Adjei, A. A., Oct 2005, In : Clinical lung cancer. 7 Suppl 2, p. S56-58

Research output: Contribution to journalReview article

4 Scopus citations

Targeting apoptosis pathways in cancer therapy

Ghobrial, I. M., Witzig, T. E. & Adjei, A. A., Jan 1 2005, In : Ca-A Cancer Journal for Clinicians. 55, 3, p. 178-194 17 p.

Research output: Contribution to journalReview article

971 Scopus citations

Targeting multiple signal transduction pathways in lung cancer.

Adjei, A. A., Sep 2005, In : Clinical lung cancer. 7 Suppl 1, p. S39-44

Research output: Contribution to journalReview article

17 Scopus citations

Treating cancer by blocking cell signals

Adjei, A. A. & Hidalgo, M., Dec 1 2005, In : Journal of Clinical Oncology. 23, 23, p. 5279-5280 2 p.

Research output: Contribution to journalReview article

11 Scopus citations
2003

Farnesyltransferase inhibitors.

Adjei, A. A., 2003, In : Cancer chemotherapy and biological response modifiers. 21, p. 127-144 18 p.

Research output: Contribution to journalReview article

9 Scopus citations

Immunohistochemical assays of farnesyltransferase inhibition in patient samples.

Adjei, A. A., 2003, In : Methods in molecular medicine. 85, p. 141-145 5 p.

Research output: Contribution to journalReview article

2 Scopus citations

Novel anticancer agents in clinical development.

Adjei, A. A. & Rowinsky, E. K., Jan 1 2003, In : Cancer biology & therapy. 2, 4 Suppl 1, p. S5-15

Research output: Contribution to journalReview article

36 Scopus citations

Pemetrexed (Alimta®): A novel multitargeted antifolate agent

Adjei, A., Jan 1 2003, In : Expert Review of Anticancer Therapy. 3, 2, p. 145-156 12 p.

Research output: Contribution to journalReview article

72 Scopus citations

The role of pemetrexed (Alimta®, LY231514) in lung cancer therapy

Molina, J. R. & Adjei, A. A., Jul 2003, In : Clinical lung cancer. 5, 1, p. 21-27 7 p.

Research output: Contribution to journalReview article

16 Scopus citations
2002

Farnesyltransferase inhibitors.

Adjei, A. A., 2002, In : Cancer chemotherapy and biological response modifiers. 20, p. 151-167 17 p.

Research output: Contribution to journalReview article

5 Scopus citations

Inhibitors of the ras oncogene as therapeutic targets

Ghobrial, I. M. & Adjei, A. A., Oct 1 2002, In : Hematology/Oncology Clinics of North America. 16, 5, p. 1065-1088 24 p.

Research output: Contribution to journalReview article

24 Scopus citations

Novel targets for lung cancer therapy: Part II

Dy, G. K. & Adjei, A. A., Jul 1 2002, In : Journal of Clinical Oncology. 20, 13, p. 3016-3028 13 p.

Research output: Contribution to journalReview article

89 Scopus citations

Pemetrexed in the treatment of selected solid tumors

Adjei, A. A., Jan 1 2002, In : Seminars in oncology. 29, 2 SUPPL. 5, p. 50-53 4 p.

Research output: Contribution to journalReview article

11 Scopus citations

Preclinical and clinical studies with combinations of pemetrexed and gemcitabine

Adjei, A. A., Dec 2002, In : Seminars in oncology. 29, 6 SUPPL. 18, p. 30-34 5 p.

Research output: Contribution to journalReview article

14 Scopus citations
2001

Advances in systemic therapy of small cell cancer of the lung

Daniels, G. A. & Adjei, A. A., Jan 1 2001, In : Expert review of anticancer therapy. 1, 2, p. 211-221 11 p.

Research output: Contribution to journalReview article

6 Scopus citations

Blocking oncogenic Ras signaling for cancer therapy

Adjei, A. A., Jul 18 2001, In : Journal of the National Cancer Institute. 93, 14, p. 1062-1074 13 p.

Research output: Contribution to journalReview article

691 Scopus citations