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1976 …2019
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Research Output 1985 2019

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Article
2019
1 Citation (Scopus)

5-year overall survival in patients with lung cancer eligible or ineligible for screening according to US Preventive Services Task Force criteria: a prospective, observational cohort study

Luo, Y. H., Luo, L., Wampfler, J. A., Wang, Y., Liu, D., Chen, Y. M., Adjei, A., Midthun, D. E. & Yang, P., Aug 1 2019, In : The Lancet Oncology. 20, 8, p. 1098-1108 11 p.

Research output: Contribution to journalArticle

Open Access
Advisory Committees
Observational Studies
Lung Neoplasms
Cohort Studies
Survival

A phase II study of the orally administered negative enantiomer of gossypol (AT-101), a BH3 mimetic, in patients with advanced adrenal cortical carcinoma

Xie, H., Yin, J., Shah, M. H., Menefee, M. E., Bible, K. C., Reidy-Lagunes, D., Kane, M. A., Quinn, D. I., Gandara, D. R., Erlichman, C. & Adjei, A., Jan 1 2019, In : Investigational New Drugs.

Research output: Contribution to journalArticle

Gossypol
Adrenocortical Carcinoma
Troponin
Hypokalemia
B-Cell Lymphoma

Pathologic Considerations and Standardization in Mesothelioma Clinical Trials

Tsao, M. S., Carbone, M., Galateau-Salle, F., Moreira, A. L., Nicholson, A. G., Roden, A., Adjei, A., Aubry, M. C., Fennell, D. A., Gomez, D., Harpole, D., Hesdorffer, M., Hirsch, F. R., Liu, G., Malik, S., Nowak, A., Peikert, T. D., Salgia, R., Szlosarek, P., Taioli, E. & 3 others, Yang, H., Tsao, A. & Mansfield, A., Jan 1 2019, (Accepted/In press) In : Journal of Thoracic Oncology.

Research output: Contribution to journalArticle

Mesothelioma
Clinical Trials
National Cancer Institute (U.S.)
Pleura
Specimen Handling
2 Citations (Scopus)

Sex Differences in Tolerability to Anti-Programmed Cell Death Protein 1 Therapy in Patients with Metastatic Melanoma and Non-Small Cell Lung Cancer: Are We All Equal?

Duma, N., Abdel-Ghani, A., Yadav, S., Hoversten, K. P., Reed, C. T., Sitek, A. N., Enninga, E. A. L., Paludo, J., Aguilera, J. V., Leventakos, K., Lou, Y., Kottschade, L. A., Dong, H. M., Mansfield, A., Manochakian, R., Adjei, A. & Dronca, R. S., Jan 1 2019, In : Oncologist.

Research output: Contribution to journalArticle

Programmed Cell Death 1 Receptor
Non-Small Cell Lung Carcinoma
Sex Characteristics
Melanoma
Therapeutics
2018
1 Citation (Scopus)

A Phase Ib Study of the FGFR/VEGFR Inhibitor Dovitinib with Gemcitabine and Capecitabine in Advanced Solid Tumor and Pancreatic Cancer Patients

Ma, W. W., Xie, H., Fetterly, G., Pitzonka, L., Whitworth, A., Levea, C., Wilton, J., Mantione, K., Schihl, S., Dy, G. K., Boland, P., Iyer, R., Tan, W., Brady, W., Straubinger, R. M. & Adjei, A., Jan 1 2018, (Accepted/In press) In : American Journal of Clinical Oncology: Cancer Clinical Trials.

Research output: Contribution to journalArticle

gemcitabine
Pancreatic Neoplasms
Maximum Tolerated Dose
Neoplasms
Biliary Tract Neoplasms
tipifarnib
Farnesyltranstransferase
Epidermal Growth Factor
Protein-Tyrosine Kinases
Maximum Tolerated Dose
Pemetrexed
Vascular Endothelial Growth Factor A
Maximum Tolerated Dose
Neoplasms
Proto-Oncogene Proteins c-kit
Pharmacokinetics
Protein-Tyrosine Kinases
Appointments and Schedules
Safety
Maximum Tolerated Dose

Association between hospital volume and mortality of patients with metastatic non-small cell lung cancer

Goyal, G., Kommalapati, A., Bartley, A. C., Gunderson, T. M., Adjei, A. & Go, R. S., Aug 1 2018, In : Lung Cancer. 122, p. 214-219 6 p.

Research output: Contribution to journalArticle

Hospital Mortality
Non-Small Cell Lung Carcinoma
Survival
Mortality
Survival Analysis

Characterization of Comorbidities Limiting the Recruitment of Patients in Early Phase Clinical Trials

Duma, N., Kothadia, S. M., Azam, T. U., Yadav, S., Paludo, J., Vera Aguilera, J., Gonzalez Velez, M., Halfdanarson, T. R., Molina, J. R., Hubbard, J. M., Go, R. S., Mansfield, A. & Adjei, A., Jan 1 2018, (Accepted/In press) In : Oncologist.

Research output: Contribution to journalArticle

Patient Selection
Comorbidity
Clinical Trials
Central Nervous System
Neoplasm Metastasis
8 Citations (Scopus)

Current and Future Management of Malignant Mesothelioma: A Consensus Report from the National Cancer Institute Thoracic Malignancy Steering Committee, International Association for the Study of Lung Cancer, and Mesothelioma Applied Research Foundation

Tsao, A. S., Lindwasser, O. W., Adjei, A., Adusumilli, P. S., Beyers, M. L., Blumenthal, G. M., Bueno, R., Burt, B. M., Carbone, M., Dahlberg, S. E., de Perrot, M., Fennell, D. A., Friedberg, J., Gill, R. R., Gomez, D. R., Harpole, D. H., Hassan, R., Hesdorffer, M., Hirsch, F. R., Hmeljak, J. & 21 others, Kindler, H. L., Korn, E. L., Liu, G., Mansfield, A., Nowak, A. K., Pass, H. I., Peikert, T. D., Rimner, A., Robinson, B. W. S., Rosenzweig, K. E., Rusch, V. W., Salgia, R., Sepesi, B., Simone, C. B., Sridhara, R., Szlosarek, P., Taioli, E., Tsao, M. S., Yang, H., Zauderer, M. G. & Malik, S. M., Nov 1 2018, In : Journal of Thoracic Oncology. 13, 11, p. 1655-1667 13 p.

Research output: Contribution to journalArticle

National Cancer Institute (U.S.)
Mesothelioma
Thorax
Clinical Trials
Research
10 Citations (Scopus)

CX3CR1 identifies PD-1 therapy-responsive CD8+ T cells that withstand chemotherapy during cancer chemoimmunotherapy

Yan, Y., Cao, S., Liu, X., Harrington, S. M., Bindeman, W. E., Adjei, A., Jang, J. S., Jen, J., Li, Y., Chanana, P., Mansfield, A., Park, S. S., Markovic, S. N., Dronca, R. S. & Dong, H. M., Apr 19 2018, In : JCI insight. 3, 8

Research output: Contribution to journalArticle

Open Access
T-Lymphocytes
Drug Therapy
Aptitude
Neoplasms
Therapeutics
17 Citations (Scopus)

Development of MK-8353, an orally administered ERK1/2 inhibitor, in patients with advanced solid tumors

Moschos, S. J., Sullivan, R. J., Hwu, W. J., Ramanathan, R. K., Adjei, A., Fong, P. C., Shapira-Frommer, R., Tawbi, H. A., Rubino, J., Rush, T. S., Zhang, D., Miselis, N. R., Samatar, A. A., Chun, P., Rubin, E. H., Schiller, J., Long, B. J., Dayananth, P., Carr, D., Kirschmeier, P. & 8 others, Bishop, W. R., Deng, Y., Cooper, A., Shipps, G. W., Moreno, B. H., Robert, L., Ribas, A. & Flaherty, K. T., Feb 22 2018, In : JCI insight. 3, 4

Research output: Contribution to journalArticle

Open Access
Neoplasms
Melanoma
Clinical Trials, Phase I
Exanthema
Heterografts
8 Citations (Scopus)

Peripheral blood biomarkers correlate with outcomes in advanced non-small cell lung Cancer patients treated with anti-PD-1 antibodies

Soyano, A. E., Dholaria, B., Marin-Acevedo, J. A., Diehl, N., Hodge, D., Luo, Y., Manochakian, R., Chumsri, S., Adjei, A., Knutson, K. L. & Lou, Y., Nov 23 2018, In : Journal for ImmunoTherapy of Cancer. 6, 1, 129.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Cell Death
Lymphocyte Count
Biomarkers
Neutrophils
2 Citations (Scopus)

Survival trends among non-small-cell lung cancer patients over a decade: impact of initial therapy at academic centers

Lou, Y., Dholaria, B., Soyano, A., Hodge, D., Cochuyt, J., Manochakian, R., Ko, S. J., Thomas, M., Johnson, M. M., Patel, N. M., Miller, R. C., Adjei, A. & Ailawadhi, S., Jan 1 2018, (Accepted/In press) In : Cancer Medicine.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Survival
Therapeutics
Databases
Neoplasms

What is a “High-Impact” Journal?

Adjei, A., Jan 1 2018, (Accepted/In press) In : Journal of Thoracic Oncology.

Research output: Contribution to journalArticle

2017
28 Citations (Scopus)
Adjuvant Chemotherapy
Non-Small Cell Lung Carcinoma
Drug Therapy
docetaxel
gemcitabine
5 Citations (Scopus)

A phase IB dose-escalation study of the safety and pharmacokinetics of pictilisib in combination with either paclitaxel and carboplatin (with or without bevacizumab) or pemetrexed and cisplatin (with or without bevacizumab) in patients with advanced non–small cell lung cancer

Soria, J. C., Adjei, A., Bahleda, R., Besse, B., Ferte, C., Planchard, D., Zhou, J., Ware, J., Morrissey, K., Shankar, G., Lin, W., Schutzman, J. L., Dy, G. K. & Groen, H. J. M., Nov 1 2017, In : European Journal of Cancer. 86, p. 186-196 11 p.

Research output: Contribution to journalArticle

Pemetrexed
Carboplatin
Paclitaxel
Non-Small Cell Lung Carcinoma
Cisplatin
10 Citations (Scopus)

A phase I clinical trial and independent patient-derived xenograft study of combined targeted treatment with dacomitinib and figitumumab in advanced solid tumors

Calvo, E., Soria, J. C., Ma, W. W., Wang, T., Bahleda, R., Tolcher, A. W., Gernhardt, D., O'Connell, J., Millham, R., Giri, N., Wick, M. J., Adjei, A. & Hidalgo, M., Mar 1 2017, In : Clinical Cancer Research. 23, 5, p. 1177-1185 9 p.

Research output: Contribution to journalArticle

Clinical Trials, Phase I
Heterografts
Adenoid Cystic Carcinoma
Neoplasms
Therapeutics
9 Citations (Scopus)

A phase I dose-escalation study of TAK-733, an investigational oral MEK inhibitor, in patients with advanced solid tumors

Adjei, A., LoRusso, P., Ribas, A., Sosman, J. A., Pavlick, A., Dy, G. K., Zhou, X., Gangolli, E., Kneissl, M., Faucette, S., Neuwirth, R. & Bózon, V., Feb 1 2017, In : Investigational New Drugs. 35, 1, p. 47-58 12 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase Kinases
Neoplasms
Melanoma
Maximum Tolerated Dose
Phosphorylation
21 Citations (Scopus)

First-in-human phase I Study of the tamoxifen metabolite Z-endoxifen in women with endocrine-refractory metastatic breast cancer

Goetz, M. P., Suman, V. J., Reid, J. M., Northfelt, D. W., Mahr, M. A., Ralya, A. T., Kuffel, M., Visscher, S. A., Kipp, B. R., Liu, M. C., Hawse, J. R., Ames, M. M., Ingle Buhrow, J. N., Safgren, S. L., McGovern, R. M., Black, J., Dockter, T., Haddad, T. C., Erlichman, C., Adjei, A. & 7 others, Collins, D., Streicher, H., Chalmers, Z. R., Frampton, G., Hawse, J. R., Doroshow, J. H. & Collins, J. M., Oct 20 2017, In : Journal of Clinical Oncology. 35, 30, p. 3391-3400 10 p.

Research output: Contribution to journalArticle

Tamoxifen
Breast Neoplasms
Maximum Tolerated Dose
Mutation
Cytochrome P-450 CYP2D6
6 Citations (Scopus)

Long-Term Results of a Trial of Concurrent Chemotherapy and Escalating Doses of Radiation for Unresectable Non–Small Cell Lung Cancer: NCCTG N0028 (Alliance)

Mayo Clinic, North Central Cancer Treatment Group, Apr 1 2017, In : Journal of Thoracic Oncology. 12, 4, p. 697-703 7 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Radiation
Drug Therapy
Radiotherapy
Maximum Tolerated Dose
5 Citations (Scopus)

Management of Multifocal Lung Cancer: Results of a Survey

Leventakos, K., Peikert, T. D., Midthun, D. E., Molina, J. R., Blackmon, S., Nichols, F. C., Garces, Y. I., Hallemeier, C., Murphy, S. J., Vasmatzis, G., Kratz, S. L., Holland, W. P., Thomas, C. F., Mullon, J. J., Shen, K. R., Cassivi, S. D., Marks, R. S., Aubry, M. C., Adjei, A., Yang, P. & 4 others, Allen, M. S., Edell, E., Wigle, D. A. & Mansfield, A., 2017, (Accepted/In press) In : Journal of Thoracic Oncology.

Research output: Contribution to journalArticle

Lung Neoplasms
Neoplasm Metastasis
Mediastinoscopy
Mediastinum
Bronchoscopy
3 Citations (Scopus)

Quality-of-life (QOL) during screening for phase 1 trial studies in patients with advanced solid tumors and its impact on risk for serious adverse events

Anwar, S., Tan, W., Hong, C. C., Admane, S., Dozier, A., Siedlecki, F., Whitworth, A., Diraddo, A. M., DePaolo, D., Jacob, S. M., Ma, W. W., Miller, A., Adjei, A. & Dy, G. K., Jul 1 2017, In : Cancers. 9, 7, 73.

Research output: Contribution to journalArticle

Quality of Life
Social Support
Comorbidity
Neoplasms
Outcome Assessment (Health Care)
2 Citations (Scopus)

Validation of progression-free survival as a surrogate endpoint for overall survival inmalignant mesothelioma: Analysis of cancer and leukemia group B and north central cancer treatment group (Alliance) trials

Wang, X., Wang, X., Hodgson, L., George, S. L., Sargent, D. J., Foster, N. R., Ganti, A. K., Stinchcombe, T. E., Crawford, J., Kratzke, R., Adjei, A., Kindler, H. L., Vokes, E. E. & Pang, H., Feb 10 2017, In : Oncologist. 22, 2, p. 189-198 10 p.

Research output: Contribution to journalArticle

Mesothelioma
Disease-Free Survival
Leukemia
Biomarkers
Survival
2016
18 Citations (Scopus)

A first-in-human phase I study to evaluate the MEK1/2 inhibitor, cobimetinib, administered daily in patients with advanced solid tumors

Rosen, L. S., LoRusso, P., Ma, W. W., Goldman, J. W., Weise, A., Colevas, A. D., Adjei, A., Yazji, S., Shen, A., Johnston, S., Hsieh, H. J., Chan, I. T. & Sikic, B. I., Oct 1 2016, In : Investigational New Drugs. 34, 5, p. 604-613 10 p.

Research output: Contribution to journalArticle

Neoplasms
Appointments and Schedules
Exanthema
Maximum Tolerated Dose
Pharmacokinetics
6 Citations (Scopus)

A phase I study of the safety, Pharmacokinetics, and Pharmacodynamics of combination therapy with refametinib plus sorafenib in patients with advanced cancer

Adjei, A., Richards, D. A., El-Khoueiry, A., Braiteh, F., Becerra, C. H. R., Jr, J. J. S., Hezel, A. F., Sherman, M., Garbo, L., Leffingwell, D. P., Iverson, C., Miner, J. N., Shen, Z., Yeh, L. T., Gunawan, S., Wilson, D. M., Manhard, K. J., Rajagopalan, P., Krissel, H. & Clendeninn, N. J., May 15 2016, In : Clinical Cancer Research. 22, 10, p. 2368-2376 9 p.

Research output: Contribution to journalArticle

Maximum Tolerated Dose
Pharmacokinetics
Safety
Neoplasms
Therapeutics
69 Citations (Scopus)

Consensus report of the 2015 Weinman international conference on mesothelioma

Carbone, M., Kanodia, S., Chao, A., Miller, A., Wali, A., Weissman, D., Adjei, A., Baumann, F., Boffetta, P., Buck, B., De Perrot, M., Dogan, A. U., Gavett, S., Gualtieri, A., Hassan, R., Hesdorffer, M., Hirsch, F. R., Larson, D., Mao, W., Masten, S. & 8 others, Pass, H. I., Peto, J., Pira, E., Steele, I., Tsao, A., Woodard, G. A., Yang, H. & Malik, S., Jan 1 2016, In : Journal of Thoracic Oncology. 11, 8, p. 1246-1262 17 p.

Research output: Contribution to journalArticle

Asbestos
Mesothelioma
Mineral Fibers
BRCA1 Protein
Biomarkers
8 Citations (Scopus)

Efficacy of focal adhesion kinase inhibition in non-small cell lung cancer with oncogenically activated MAPK pathways

Zhang, H., Shao, H., Golubovskaya, V. M., Chen, H., Cance, W., Adjei, A. & Dy, G. K., Jul 12 2016, In : British Journal of Cancer. 115, 2, p. 203-211 9 p.

Research output: Contribution to journalArticle

Focal Adhesion Protein-Tyrosine Kinases
Non-Small Cell Lung Carcinoma
Lung Neoplasms
Epidermal Growth Factor Receptor
Mutation
32 Citations (Scopus)

Enrollment trends and disparity among patients with lung cancer in national clinical trials, 1990 to 2012

Pang, H. H., Wang, X., Stinchcombe, T. E., Wong, M. L., Cheng, P., Ganti, A. K., Sargent, D. J., Zhang, Y., Hu, C., Mandrekar, S. J., Redman, M. W., Manola, J. B., Schilsky, R. L., Cohen, H. J., Bradley, J. D., Adjei, A., Gandara, D., Ramalingam, S. S. & Vokes, E. E., Nov 20 2016, In : Journal of Clinical Oncology. 34, 33, p. 3992-3999 8 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Clinical Trials
Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
Population
44 Citations (Scopus)

MM-151 overcomes acquired resistance to cetuximab and panitumumab in colorectal cancers harboring EGFR extracellular domain mutations

Arena, S., Siravegna, G., Mussolin, B., Kearns, J. D., Wolf, B. B., Misale, S., Lazzari, L., Bertotti, A., Trusolino, L., Adjei, A., Montagut, C., Di Nicolantonio, F., Nering, R. & Bardelli, A., Feb 3 2016, In : Science Translational Medicine. 8, 324, 324ra14.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Colorectal Neoplasms
Mutation
Antibodies
Cetuximab
2015
148 Citations (Scopus)

2nd ESMO Consensus Conference in Lung Cancer: Locally advanced stage III non-small-cell lung cancer

Panel Members, Jan 1 2015, In : Annals of Oncology. 26, 8, p. 1573-1588 16 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Lung Neoplasms
Molecular Pathology
Neoplasms
Biomarkers
17 Citations (Scopus)

A phase i study of the histone deacetylase (HDAC) inhibitor entinostat, in combination with sorafenib in patients with advanced solid tumors

Ngamphaiboon, N., Dy, G. K., Ma, W. W., Zhao, Y., Reungwetwattana, T., Depaolo, D., Ding, Y., Brady, W., Fetterly, G. & Adjei, A., Jan 1 2015, In : Investigational New Drugs. 33, 1, p. 225-232 8 p.

Research output: Contribution to journalArticle

Histone Deacetylase Inhibitors
Hand-Foot Syndrome
Neoplasms
Fatigue
Muscle Weakness
35 Citations (Scopus)

APhase i study of the SMAC-mimetic birinapant in adults with refractory solid tumorsor lymphoma

Amaravadi, R. K., Schilder, R. J., Martin, L. P., Levin, M., Graham, M. A., Weng, D. E. & Adjei, A., Nov 1 2015, In : Molecular Cancer Therapeutics. 14, 11, p. 2569-2575 7 p.

Research output: Contribution to journalArticle

Caspases
Lymphoma
Maximum Tolerated Dose
Neoplasms
Colorectal Neoplasms
15 Citations (Scopus)

Lung cancer and metastasis: new opportunities and challenges

Wang, X. & Adjei, A., Jun 1 2015, In : Cancer and Metastasis Reviews. 34, 2, p. 169-171 3 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Neoplasm Metastasis
Neoplasm Genes
Genes
Computational Biology
18 Citations (Scopus)

Multitrial evaluation of progression-free survival as a surrogate end point for overall survival in first-line extensive-stage small-cell lung cancer

Foster, N. R., Renfro, L. A., Schild, S. E., Redman, M. W., Wang, X. F., Dahlberg, S. E., Ding, K., Bradbury, P. A., Ramalingam, S. S., Gandara, D. R., Shibata, T., Saijo, N., Vokes, E. E., Adjei, A. & Mandrekar, S. J., Jul 4 2015, In : Journal of Thoracic Oncology. 10, 7, p. 1099-1106 8 p.

Research output: Contribution to journalArticle

Small Cell Lung Carcinoma
Disease-Free Survival
Biomarkers
Survival
Validation Studies
4 Citations (Scopus)

New strategies to develop new medications for lung cancer and metastasis

Zhao, Y. & Adjei, A., Jun 1 2015, In : Cancer and Metastasis Reviews. 34, 2, p. 265-275 11 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Neoplasm Metastasis
Non-Small Cell Lung Carcinoma
Survival
Therapeutics
6 Citations (Scopus)

Phase 1b study of the oral gemcitabine 'Pro-drug' LY2334737 in combination with capecitabine in patients with advanced solid tumors

Infante, J. R., Benhadji, K. A., Dy, G. K., Fetterly, G., Ma, W. W., Bendell, J., Callies, S. & Adjei, A., Apr 1 2015, In : Investigational New Drugs. 33, 2, p. 432-439 8 p.

Research output: Contribution to journalArticle

gemcitabine
Prodrugs
Neoplasms
Pharmacokinetics
Drug Interactions
28 Citations (Scopus)

Phase 1 trial of tivantinib in combination with sorafenib in adult patients with advanced solid tumors

Puzanov, I., Sosman, J., Santoro, A., Saif, M. W., Goff, L., Dy, G. K., Zucali, P., Means-Powell, J. A., Ma, W. W., Simonelli, M., Martell, R., Chai, F., Lamar, M., Savage, R. E., Schwartz, B. & Adjei, A., Jan 1 2015, In : Investigational New Drugs. 33, 1, p. 159-168 10 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Neoplasms
Renal Cell Carcinoma
Melanoma
Therapeutics
165 Citations (Scopus)

Targeting angiogenesis in cancer therapy: Moving beyond vascular endothelial growth factor

Zhao, Y. & Adjei, A., Jan 1 2015, In : Oncologist. 20, 6, p. 660-673 14 p.

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor A
Platelet-Derived Growth Factor Receptors
Fibroblast Growth Factor Receptors
Neoplasms
Therapeutics
2014
174 Citations (Scopus)

2nd ESMO consensus conference on lung cancer: Early-stage non-small-cell lung cancer consensus on diagnosis, treatment and follow-up

Vansteenkiste, J., Crinò, L., Dooms, C., Douillard, J. Y., Faivre-Finn, C., Lim, E., Rocco, G., Senan, S., van Schil, P., Veronesi, G., Stahel, R., Peters, S., Felip, E., Kerr, K., Besse, B., Eberhardt, W., Edelman, M., Mok, T., O'Byrne, K., Novello, S. & 15 others, Bubendorf, L., Marchetti, A., Baas, P., Reck, M., Syrigos, K., Paz-Ares, L., Smit, E. F., Meldgaard, P., Adjei, A., Nicolson, M., Weder, W., de Ruysscher, D., Le Pechoux, C., de Leyn, P. & Westeel, V., Jan 1 2014, In : Annals of Oncology. 25, 8, p. 1462-1474 13 p., mdu089.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Lung Neoplasms
Molecular Pathology
Neoplasms
Biomarkers
132 Citations (Scopus)

2nd ESMO Consensus Conference on Lung Cancer: Non-small-cell lung cancer first-line/second and further lines in advanced disease

Besse, B., Adjei, A., Baas, P., Meldgaard, P., Nicolson, M., Paz-Ares, L., Reck, M., Smit, E. F., Syrigos, K., Stahel, R., Felip, E., Peters, S., Stahel, R., Felip, E., Peters, S., Kerr, K., Besse, B., Vansteenkiste, J., Eberhardt, W., Edelman, M. & 27 others, Mok, T., O'Byrne, K., Novello, S., Bubendorf, L., Marchetti, A., Baas, P., Reck, M., Syrigos, K., Paz-Ares, L., Smit, E. F., Meldgaard, P., Adjei, A., Nicolson, M., Crinò, L., Van Schil, P., Senan, S., Faivre-Finn, C., Rocco, G., Veronesi, G., Douillard, J. Y., Lim, E., Dooms, C., Weder, W., De Ruysscher, D., Le Pechoux, C., De Leyn, P. & Westeel, V., Jan 1 2014, In : Annals of Oncology. 25, 8, p. 1475-1484 10 p., mdu123.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Lung Neoplasms
Molecular Pathology
Neoplasms
Biomarkers
18 Citations (Scopus)

A Phase I/II Study of Bortezomib in Combination with Paclitaxel, Carboplatin and Concurrent Thoracic Radiation Therapy for Non-Small Cell Lung Cancer: NCCTG-N0321

Zhao, Y., Foster, N. R., Meyers, J. P., Thomas, S. P., Northfelt, D. W., Rowland, K. M., Mattar, B. I., Johnson, D. B., Molina, J. R., Mandrekar, S. J., Schild, S. E., Bearden, J. D., Aubry, M. C. & Adjei, A., Sep 22 2014, (Accepted/In press) In : Journal of Thoracic Oncology.

Research output: Contribution to journalArticle

Carboplatin
Paclitaxel
Non-Small Cell Lung Carcinoma
Radiotherapy
Thorax
19 Citations (Scopus)

A phase II multicentre study of ziv-aflibercept in combination with cisplatin and pemetrexed in patients with previously untreated advanced/metastatic non-squamous non-small cell lung cancer

Chen, H., Modiano, M. R., Neal, J. W., Brahmer, J. R., Rigas, J. R., Jotte, R. M., Leighl, N. B., Riess, J. W., Kuo, C. J., Liu, L., Gao, B., Dicioccio, A. T., Adjei, A. & Wakelee, H. A., Feb 4 2014, In : British Journal of Cancer. 110, 3, p. 602-608 7 p.

Research output: Contribution to journalArticle

Pemetrexed
Non-Small Cell Lung Carcinoma
Cisplatin
Multicenter Studies
Posterior Leukoencephalopathy Syndrome
21 Citations (Scopus)

A phase II trial of the Src-kinase inhibitor saracatinib after four cycles of chemotherapy for patients with extensive stage small cell lung cancer: NCCTG trial N-0621

Molina, J. R., Foster, N. R., Reungwetwattana, T., Nelson, G. D., Grainger, A. V., Steen, P. D., Stella, P. J., Marks, R. S., Wright, J. & Adjei, A., 2014, In : Lung Cancer. 85, 2, p. 245-250 6 p.

Research output: Contribution to journalArticle

src-Family Kinases
Small Cell Lung Carcinoma
Drug Therapy
Disease-Free Survival
Survival Rate
1 Citation (Scopus)

Cerebral nocardiosis mimicking multiple brain metastases in a patient with locally advanced non-small-cell lung cancer

Voide, C., Zimmermann, S., Adjei, A., Betticher, D. C., Meuli, R., Prod'hom, G., Giulieri, S. & Peters, S., Mar 1 2014, In : Journal of Thoracic Oncology. 9, 3

Research output: Contribution to journalArticle

17 Citations (Scopus)

Enhanced FGFR signalling predisposes pancreatic cancer to the effect of a potent FGFR inhibitor in preclinical models

Zhang, H., Hylander, B. L., Levea, C., Repasky, E. A., Straubinger, R. M., Adjei, A. & Ma, W. W., Jan 21 2014, In : British Journal of Cancer. 110, 2, p. 320-329 10 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor Receptors
Pancreatic Neoplasms
Small Interfering RNA
Neoplasms
Biomarkers
14 Citations (Scopus)

Farnesyltransferase inhibitor tipifarnib inhibits rheb prenylation and stabilizes bax in acute myelogenous leukemia cells

Ding, H., McDonald, J. S., Yun, S., Schneider, P. A., Peterson, K. L., Flatten, K. S., Loegering, D. A., Oberg, A. L., Riska, S. M., Huang, S., Sinicrope, F. A., Adjei, A., Karp, J. E., Meng, X. W. & Kaufmann, S. H., Jan 1 2014, In : Haematologica. 99, 1, p. 60-69 10 p.

Research output: Contribution to journalArticle

tipifarnib
Farnesyltranstransferase
Prenylation
Puma
Acute Myeloid Leukemia
8 Citations (Scopus)

NCCTG N0821 (Alliance): A phase ii first-line study of pemetrexed, carboplatin, and bevacizumab in elderly patients with advanced nonsquamous non-small-cell lung cancer with good performance status

Dy, G. K., Molina, J. R., Qi, Y., Ansari, R., Thomas, S., Ross, H. J., Soori, G., Anderson, D., Christine Aubry, M., Meyers, J., Adjei, A. A., Mandrekar, S. J. & Adjei, A., 2014, In : Journal of Thoracic Oncology. 9, 8, p. 1146-1153 8 p.

Research output: Contribution to journalArticle

Pemetrexed
Carboplatin
Non-Small Cell Lung Carcinoma
Quality of Life
Confidence Intervals
4 Citations (Scopus)

Phase II study of perioperative chemotherapy with cisplatin and pemetrexed in non-small-cell lung cancer

Dy, G. K., Bogner, P. N., Tan, W., Demmy, T. L., Farooq, A., Chen, H., Yendamuri, S. S., Nwogu, C. E., Bushunow, P. W., Gannon, J., Adjei, A. A., Adjei, A. & Ramnath, N., Feb 1 2014, In : Journal of Thoracic Oncology. 9, 2, p. 222-230 9 p.

Research output: Contribution to journalArticle

Pemetrexed
Non-Small Cell Lung Carcinoma
Cisplatin
Drug Therapy
Disease-Free Survival