• 4039 Citations
  • 38 Scopus h-Index
1986 …2019
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Research Output 1987 2019

142 Citations (Scopus)

Aberrant accumulation of EFEMP1 underlies drusen formation in Malattia Leventinese and age-related macular degeneration

Marmorstein, L. Y., Munier, F. L., Arsenijevic, Y., Schorderet, D. F., McLaughlin, P. J., Chung, D., Traboulsi, E. & Marmorstein, A. D., Oct 1 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 20, p. 13067-13072 6 p.

Research output: Contribution to journalArticle

Macular Degeneration
Retinal Pigment Epithelium
Retinal Drusen
Bruch Membrane
Mutant Proteins
45 Citations (Scopus)

A model of best vitelliform macular dystrophy in rats

Marmorstein, A. D., Stanton, J. B., Yocom, J., Bakall, B., Schiavone, M. T., Wadelius, C., Marmorstein, L. Y. & Peachey, N. S., Oct 2004, In : Investigative Ophthalmology and Visual Science. 45, 10, p. 3733-3739 7 p.

Research output: Contribution to journalArticle

Vitelliform Macular Dystrophy
Light
Retinal Pigments
Cell Membrane
Fluorescence Microscopy

An exogenous plasma membrane protein is polarized on the apical surface of the Retinal Pigment Epithelium (RPE) in vivo and in vitro

Marmorstein, A. D., Yeaman, C., Bonilha, V. L., Anglade, E., Csaky, K. & Rodriguez-Boulan, E., Feb 15 1996, In : Investigative Ophthalmology and Visual Science. 37, 3

Research output: Contribution to journalArticle

Retinal Pigment Epithelium
Blood Proteins
Membrane Proteins
Cell Membrane
Confocal Microscopy
1 Citation (Scopus)

A novel missense mutation in BEST1 associated with an autosomal-dominant vitreoretinochoroidopathy (ADVIRC) phenotype

Mano, F., LoBue, S. A., Olsen, T., Marmorstein, A. D. & Pulido, J. S., Jan 1 2018, (Accepted/In press) In : Ophthalmic Genetics.

Research output: Contribution to journalArticle

Missense Mutation
Phenotype
Optical Coherence Tomography
Hemorrhage
Mutation
42 Citations (Scopus)

Apical polarity of N-CAM and EMMPRIN in retinal pigment epithelium resulting from suppression of basolateral signal recognition

Marmorstein, A. D., Gan, Y. C., Bonilha, V. L., Finnemann, S. C., Csaky, K. G. & Rodriguez-Boulan, E., Aug 10 1998, In : Journal of Cell Biology. 142, 3, p. 697-710 14 p.

Research output: Contribution to journalArticle

CD147 Antigens
Retinal Pigments
Retinal Pigment Epithelium
Epithelial Cells
Nerve Growth Factor Receptor
32 Citations (Scopus)

Apical sorting of influenza hemagglutinin by transcytosis in retinal pigment epithelium

Bonilha, V. L., Marmorstein, A. D., Cohen-Gould, L. & Rodriguez-Boulan, E., Aug 1997, In : Journal of Cell Science. 110, 15, p. 1717-1727 11 p.

Research output: Contribution to journalArticle

Transcytosis
Retinal Pigment Epithelium
Vesicular Stomatitis
Hemagglutinins
Human Influenza

Apical sorting pathways in Retinal Pigment Epithelial (RPE) cells

Bonilha, V. L., Marmorstein, A. D., Sparrow, J. R. & Rodriguez-Boulan, E., Feb 15 1996, In : Investigative Ophthalmology and Visual Science. 37, 3

Research output: Contribution to journalArticle

Retinal Pigments
Epithelial Cells
trans-Golgi Network
Human Influenza
Temperature

Application of ratiometry to fundus autofluorescence imaging

Marmorstein, A. D., 2005, Optics InfoBase Conference Papers. Optical Society of America

Research output: Chapter in Book/Report/Conference proceedingConference contribution

blindness
degeneration
Imaging techniques
causes
22 Citations (Scopus)

Autosomal recessive bestrophinopathy is not associated with the loss of bestrophin-1 anion channel function in a patient with a novel BEST1 mutation

Johnson, A. A., Bachman, L. A., Gilles, B. J., Cross, S. D., Stelzig, K. E., Resch, Z. T., Marmorstein, L. Y., Pulido, J. S. & Marmorstein, A. D., 2015, In : Investigative Ophthalmology and Visual Science. 56, 8, p. 4619-4630 12 p.

Research output: Contribution to journalArticle

Anions
Mutation
Madin Darby Canine Kidney Cells
Pluripotent Stem Cells
HEK293 Cells
25 Citations (Scopus)

Best1 is a gene regulated by nerve injury and required for Ca 2+-activated Cl- current expression in axotomized sensory neurons

Boudes, M., Sar, C., Menigoz, A., Hilaire, C., Péquignot, M. O., Kozlenkov, A., Marmorstein, A. D., Carroll, P., Valmier, J. & Scamps, F., Aug 12 2009, In : Journal of Neuroscience. 29, 32, p. 10063-10071 9 p.

Research output: Contribution to journalArticle

Sensory Receptor Cells
Chlorides
Wounds and Injuries
Genes
Neurons

Best1 is a gene regulated by nerve injury and required for Ca 2+-activated Cl- current expression in axotomized sensory neurons (Journal of Neuroscience (2009) (10063-10071))

Boudes, M., Sar, C., Menigoz, A., Hilaire, C., Péquignot, M. O., Kozlenkov, A., Marmorstein, A. D., Carroll, P., Valmier, J. & Scamps, F., Nov 18 2009, In : Journal of Neuroscience. 29, 46

Research output: Contribution to journalArticle

Sensory Receptor Cells
Neurosciences
Wounds and Injuries
Genes
292 Citations (Scopus)

Bestrophin, the product of the Best vitelliform macular dystrophy gene (VMD2), localizes to the basolateral plasma membrane of the retinal pigment epithelium

Marmorstein, A. D., Marmorstein, L. Y., Rayborn, M., Wang, X., Hollyfield, J. G. & Petrukhin, K., Nov 7 2000, In : Proceedings of the National Academy of Sciences of the United States of America. 97, 23, p. 12758-12763 6 p.

Research output: Contribution to journalArticle

Vitelliform Macular Dystrophy
Retinal Pigment Epithelium
Cell Membrane
Electrooculography
Genes
39 Citations (Scopus)

Bestrophin 1 and retinal disease

Johnson, A. A., Guziewicz, K. E., Lee, C. J., Kalathur, R. C., Pulido, J. S., Marmorstein, L. Y. & Marmorstein, A. D., Nov 11 2016, (Accepted/In press) In : Progress in Retinal and Eye Research.

Research output: Contribution to journalArticle

Vitelliform Macular Dystrophy
Retinal Diseases
Retinitis Pigmentosa
Retinal Pigment Epithelium
Ion Channels
18 Citations (Scopus)

Bestrophin-1 influences transepithelial electrical properties and Ca<sup>2+</sup>signaling in human retinal pigment epithelium

Marmorstein, A. D., Kinnick, T. R., Stanton, J. B., Johnson, A. A., Lynch, R. M. & Marmorstein, L. Y., Apr 1 2015, In : Molecular Vision. 21, p. 347-359 13 p.

Research output: Contribution to journalArticle

Retinal Pigment Epithelium
Vitelliform Macular Dystrophy
Anions
HEK293 Cells
Adenosine Triphosphate
10 Citations (Scopus)

Bestrophin 2 is expressed in human non-pigmented ciliary epithelium but not retinal pigment epithelium

Zhang, Y., Patil, R. V. & Marmorstein, A. D., 2010, In : Molecular Vision. 16, p. 200-206 7 p.

Research output: Contribution to journalArticle

Retinal Pigment Epithelium
Epithelium
Ciliary Body
Immunoprecipitation
Fluorescent Antibody Technique
43 Citations (Scopus)

Bestrophin-2 is involved in the generation of intraocular pressure

Bakall, B., McLaughlin, P., Stanton, J. B., Zhang, Y., Hartzell, H. C., Marmorstein, L. Y. & Marmorstein, A. D., Apr 2008, In : Investigative Ophthalmology and Visual Science. 49, 4, p. 1563-1570 8 p.

Research output: Contribution to journalArticle

Intraocular Pressure
Epithelium
Colon
Exons
Staining and Labeling
56 Citations (Scopus)

Bestrophin-2 mediates bicarbonate transport by goblet cells in mouse colon

Yu, K., Lujan, R., Marmorstein, A. D., Gabriel, S. & Hartzell, H. C., May 3 2010, In : Journal of Clinical Investigation. 120, 5, p. 1722-1735 14 p.

Research output: Contribution to journalArticle

Goblet Cells
Bicarbonates
Cholinergic Agents
Anions
Colon
61 Citations (Scopus)

Bestrophin interacts physically and functionally with protein phosphatase 2A

Marmorstein, L. Y., McLaughlin, P. J., Brett Stanton, J., Yan, L., Crabb, J. W. & Marmorstein, A. D., Aug 23 2002, In : Journal of Biological Chemistry. 277, 34, p. 30591-30597 7 p.

Research output: Contribution to journalArticle

Protein Phosphatase 2
Phosphorylation
Retinal Pigments
Electrooculography
Epithelial Cells
177 Citations (Scopus)

Caveolin-2 localizes to the Golgi complex but redistributes to plasma membrane, caveolae, and rafts when co-expressed with caveolin-1

Mora, R., Bonilha, V. L., Marmorstein, A. D., Scherer, P. E., Brown, D., Lisanti, M. P. & Rodriguez-Boulan, E., Sep 3 1999, In : Journal of Biological Chemistry. 274, 36, p. 25708-25717 10 p.

Research output: Contribution to journalArticle

Caveolin 2
Caveolin 1
Caveolae
Golgi Apparatus
Cell membranes
1 Citation (Scopus)

Cell Surface Biotinylation and Other Techniques for Determination of Surface Polarity of Epithelial Monolayers

Deora, A., Chatterjee, S., Marmorstein, A. D., Zurzolo, C., Le Bivic, A. & Rodriguez-Boulan, E., 2006, Cell Biology, Four-Volume Set. Elsevier Inc., Vol. 2. p. 241-249 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Biotinylation
Monolayers
Membrane Proteins
Biotin
Starvation

Comparison of integrin expression between the rat Retinal Pigment Epithelium (RPE) and the RPE-J cell line

Finnemann, S., Marmorstein, A. D. & Rodriguez-Boulan, E., Feb 15 1996, In : Investigative Ophthalmology and Visual Science. 37, 3

Research output: Contribution to journalArticle

Retinal Pigment Epithelium
Integrins
Cell Line
Western Blotting
Integrin alpha Chains
33 Citations (Scopus)

Contribution of Kir4.1 to the mouse electroretinogram

Wu, J., Marmorstein, A. D., Kofuji, P. & Peachey, N. S., Sep 1 2004, In : Molecular Vision. 10, p. 650-654 5 p.

Research output: Contribution to journalArticle

Retinal Pigment Epithelium
Dark Adaptation
Light
Cornea
Polymerase Chain Reaction
7 Citations (Scopus)

Control of maintenance and regeneration of planarian eyes by ovo

Cross, S. D., Johnson, A. A., Gilles, B. J., Bachman, L. A., Inoue, T., Agata, K., Marmorstein, L. Y. & Marmorstein, A. D., Nov 1 2015, In : Investigative Ophthalmology and Visual Science. 56, 12, p. 7604-7610 7 p.

Research output: Contribution to journalArticle

Planarians
Regeneration
Maintenance
RNA Interference
Arrestin
6 Citations (Scopus)

Control of outflow resistance by soluble adenylyl cyclase

Lee, Y. S. & Marmorstein, A. D., Mar 1 2014, In : Journal of Ocular Pharmacology and Therapeutics. 30, 2-3, p. 138-142 5 p.

Research output: Contribution to journalArticle

Adenylyl Cyclases
Glaucoma
Pharmaceutical Preparations
Low Tension Glaucoma
Ocular Hypertension

Corrigendum to "Disease-causing mutations associated with four bestrophinopathies exhibit disparate effects on the localization, but not the oligomerization, of Bestrophin-1" [Exp. Eye Res. 121 (2014) 74-85] DOI: 10.1016/j.exer.2014.02.006

Johnson, A. A., Lee, Y. S., Chadburn, A. J., Tammaro, P., Manson, F. D., Marmorstein, L. Y. & Marmorstein, A. D., Oct 1 2014, In : Experimental Eye Research. 127, p. 300 1 p.

Research output: Contribution to journalComment/debate

Mutation
corrigendum
Bestrophinopathy
4 Citations (Scopus)

Deletion of Efemp1 is protective against the development of sub-rpe deposits in mouse eyes

Stanton, J. B., Marmorstein, A. D., Zhang, Y. & Marmorstein, L. Y., Mar 1 2017, In : Investigative Ophthalmology and Visual Science. 58, 3, p. 1455-1461 7 p.

Research output: Contribution to journalArticle

High Fat Diet
Knockout Mice
Smoke
Tobacco Products
Retinal Dystrophies
16 Citations (Scopus)

Differential effects of best disease causing missense mutations on bestrophin-1 trafficking

Johnson, A. A., Lee, Y. S., Brett Stanton, J., Yu, K., Hartzell, C. H., Marmorstein, L. Y. & Marmorstein, A. D., Dec 2013, In : Human Molecular Genetics. 22, 23, p. 4688-4697 10 p., ddt316.

Research output: Contribution to journalArticle

Vitelliform Macular Dystrophy
Retinal Pigments
Missense Mutation
Mutation
Madin Darby Canine Kidney Cells
1 Citation (Scopus)

Differential Intraocular Pressure Measurements by Tonometry and Direct Cannulation after Treatment with Soluble Adenylyl Cyclase Inhibitors

Gandhi, J. K., Roy Chowdhury, U., Manzar, Z., Buck, J., Levin, L. R., Fautsch, M. P. & Marmorstein, A. D., Oct 1 2017, In : Journal of Ocular Pharmacology and Therapeutics. 33, 8, p. 574-581 8 p.

Research output: Contribution to journalArticle

Manometry
Acepromazine
Intraocular Pressure
Catheterization
Xylazine
20 Citations (Scopus)

Disease-causing mutations associated with four bestrophinopathies exhibit disparate effects on the localization, but not the oligomerization, of Bestrophin-1

Johnson, A. A., Lee, Y. S., Chadburn, A. J., Tammaro, P., Manson, F. D., Marmorstein, L. Y. & Marmorstein, A. D., 2014, In : Experimental Eye Research. 121, p. 74-85 12 p.

Research output: Contribution to journalArticle

Vitelliform Macular Dystrophy
Mutation
Retinitis Pigmentosa
Cell Membrane
Retinal Diseases
4 Citations (Scopus)

Disease modeling studies using induced pluripotent stem cells: Are we using enough controls?

Johnson, A. A., Andrews-Pfannkoch, C., Nelson, T. J., Pulido, J. S. & Marmorstein, A. D., Dec 1 2017, In : Regenerative Medicine. 12, 8, p. 899-903 5 p.

Research output: Contribution to journalReview article

Induced Pluripotent Stem Cells
Stem cells
Cell Line
8 Citations (Scopus)

Early AMD-like defects in the RPE and retinal degeneration in aged mice with RPE-specific deletion of Atg5 or Atg7

Zhang, Y., Cross, S. D., Stanton, J. B., Marmorstein, A. D., Le, Y. Z. & Marmorstein, L. Y., Apr 14 2017, In : Molecular Vision. 23, p. 228-241 14 p.

Research output: Contribution to journalArticle

Retinal Degeneration
Macular Degeneration
Autophagy
Plastics
Choroidal Neovascularization
67 Citations (Scopus)

Enhanced accumulation of A2E in individuals homozygous or heterozygous for mutations in BEST1 (VMD2)

Bakall, B., Radu, R. A., Stanton, J. B., Burke, J. M., McKay, B. S., Wadelius, C., Mullins, R. F., Stone, E. M., Travis, G. H. & Marmorstein, A. D., Jul 2007, In : Experimental Eye Research. 85, 1, p. 34-43 10 p.

Research output: Contribution to journalArticle

Vitelliform Macular Dystrophy
Lipofuscin
Mutation
Retinal Pigment Epithelium
Heterozygote
38 Citations (Scopus)

Enhanced inflow and outflow rates despite lower IOP in bestrophin-2- deficient mice

Zhang, Y., Davidson, B. R., Stamer, W. D., Barton, J. K., Marmorstein, L. Y. & Marmorstein, A. D., Feb 2009, In : Investigative Ophthalmology and Visual Science. 50, 2, p. 765-770 6 p.

Research output: Contribution to journalArticle

Intraocular Pressure
Aqueous Humor
Anterior Chamber
Venous Pressure
Epithelium
30 Citations (Scopus)

Epithelial permeability factor: A serum protein that condenses actin and opens tight junctions

Marmorstein, A. D., Mortell, K. H., Ratcliffe, D. R. & Cramer, E. B., 1992, In : American Journal of Physiology - Cell Physiology. 262, 6 31-6

Research output: Contribution to journalArticle

Tight Junctions
Actins
Blood Proteins
Permeability
Affinity chromatography
72 Citations (Scopus)

Expression and localization of bestrophin during normal mouse development

Bakall, B., Marmorstein, L. Y., Hoppe, G., Peachey, N. S., Wadelius, C. & Marmorstein, A. D., Aug 1 2003, In : Investigative Ophthalmology and Visual Science. 44, 8, p. 3622-3628 7 p.

Research output: Contribution to journalArticle

Retinal Pigment Epithelium
Electroretinography
Messenger RNA
Light Signal Transduction
Proteins
150 Citations (Scopus)

Expression of bestrophin-1, the product of the VMD2 gene, modulates voltage-dependent Ca2+ channels in retinal pigment epithelial cells

Rosenthal, R., Bakall, B., Kinnick, T., Peachey, N., Wimmers, S., Wadelius, C., Marmorstein, A. D. & Strauss, O., Jan 2006, In : FASEB Journal. 20, 1, p. 178-180 3 p.

Research output: Contribution to journalArticle

chloride channels
protein transport
gene expression regulation
ion transport
epithelial cells
15 Citations (Scopus)

Fetal bovine serum and other sera used in tissue culture increase epithelial permeability

Mortell, K. H., Marmorstein, A. D. & Cramer, E. B., 1993, In : In Vitro Cellular and Developmental Biology - Animal. 29 A, 3 I, p. 235-238 4 p.

Research output: Contribution to journalArticle

Tissue culture
Monolayers
Permeability
Acoustic impedance
Mannitol
3 Citations (Scopus)

Fibrin hydrogels as a xenofree and rapidly degradable support for transplantation of retinal pigment epithelium monolayers

Gandhi, J. K., Manzar, Z., Bachman, L. A., Andrews-Pfannkoch, C., Knudsen, T., Hill, M., Schmidt, H., Iezzi, R., Pulido, J. S. & Marmorstein, A. D., Jan 1 2017, (Accepted/In press) In : Acta Biomaterialia.

Research output: Contribution to journalArticle

Hydrogels
Retinal Pigments
Retinal Pigment Epithelium
Fibrin
Pigments
33 Citations (Scopus)

Focus on Molecules: Bestrophin (Best-1)

Marmorstein, A. D. & Kinnick, T. R., Oct 2007, In : Experimental Eye Research. 85, 4, p. 423-424 2 p.

Research output: Contribution to journalArticle

Eye Proteins
Electrooculography
Electroretinography
Lipofuscin
Retinal Degeneration
43 Citations (Scopus)

Forkhead transcription factor FoxA1 regulates sweat secretion through Bestrophin 2 anion channel and Na-K-Cl cotransporter 1

Cui, C. Y., Childress, V., Piao, Y., Michel, M., Johnson, A. A., Kunisada, M., Ko, M. S. H., Kaestner, K. H., Marmorstein, A. D. & Schlessinger, D., Jan 24 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 4, p. 1199-1203 5 p.

Research output: Contribution to journalArticle

Sodium-Potassium-Chloride Symporters
Forkhead Transcription Factors
Sweat
Anions
Sweat Glands
71 Citations (Scopus)

Formation and progression of sub-retinal pigment epithelium deposits in Efemp1 mutation knock-in mice: A model for the early pathogenic course of macular degeneration

Marmorstein, L. Y., McLaughlin, P. J., Peachey, N. S., Sasaki, T. & Marmorstein, A. D., Oct 15 2007, In : Human Molecular Genetics. 16, 20, p. 2423-2432 10 p.

Research output: Contribution to journalArticle

Retinal Pigment Epithelium
Macular Degeneration
Mutation
Bruch Membrane
Blindness
18 Citations (Scopus)

Functional abnormalities in the retinal pigment epithelium of CFTR mutant mice

Wu, J., Marmorstein, A. D. & Peachey, N. S., Aug 2006, In : Experimental Eye Research. 83, 2, p. 424-428 5 p.

Research output: Contribution to journalArticle

Retinal Pigment Epithelium
Cystic Fibrosis
Light
Ion Channels
Mutation
89 Citations (Scopus)

Functional roles of bestrophins in ocular epithelia

Marmorstein, A. D., Cross, H. E. & Peachey, N. S., May 2009, In : Progress in Retinal and Eye Research. 28, 3, p. 206-226 21 p.

Research output: Contribution to journalArticle

Vitelliform Macular Dystrophy
Epithelium
Eye Diseases
Light
Knockout Mice

Histopathologic findings in the areas of orange pigment overlying choroidal melanomas

Garcia, M. D., Salomao, D. R., Marmorstein, A. D. & Pulido, J. S., May 1 2016, In : Translational Vision Science and Technology. 5, 3, 4.

Research output: Contribution to journalArticle

Retinal Pigments
Pigments
Melanoma
Epithelial Cells
Color
1 Citation (Scopus)

Human Fibrinogen for Maintenance and Differentiation of Induced Pluripotent Stem Cells in Two Dimensions and Three Dimensions

Gandhi, J. K., Knudsen, T., Hill, M., Roy, B., Bachman, L., Pfannkoch-Andrews, C., Schmidt, K. N., Metko, M. M., Ackerman, M. J., Resch, Z., Pulido, J. S. & Marmorstein, A. D., Jan 1 2019, In : Stem Cells Translational Medicine.

Research output: Contribution to journalArticle

Open Access
Induced Pluripotent Stem Cells
Fibrinogen
Maintenance
Hydrogels
Fibrin
118 Citations (Scopus)

Human retinal pigment epithelium cells as functional models for the RPE in vivo

Ablonczy, Z., Dahrouj, M., Tang, P. H., Liu, Y., Sambamurti, K., Marmorstein, A. D. & Crosson, C. E., Nov 2011, In : Investigative Ophthalmology and Visual Science. 52, 12, p. 8614-8620 7 p.

Research output: Contribution to journalArticle

Retinal Pigment Epithelium
Vascular Endothelial Growth Factor A
Conditioned Culture Medium
Retreatment
Tight Junctions
38 Citations (Scopus)

Hydrodynamic properties of porcine bestrophin-1 in Triton X-100

Stanton, J. B., Goldberg, A. F. X., Hoppe, G., Marmorstein, L. Y. & Marmorstein, A. D., Feb 2006, In : Biochimica et Biophysica Acta - Biomembranes. 1758, 2, p. 241-247 7 p.

Research output: Contribution to journalArticle

Octoxynol
Hydrodynamics
Stoichiometry
Gel Chromatography
Swine
25 Citations (Scopus)

Identification of the retinal pigment epithelium protein RET-PE2 as CE- 9/OX-47, a member of the immunoglobulin superfamily

Finnemann, S. C., Marmorstein, A. D., Neill, J. M. & Rodriguez-Boulan, E., Oct 1997, In : Investigative Ophthalmology and Visual Science. 38, 11, p. 2366-2374 9 p.

Research output: Contribution to journalArticle

Retinal Pigment Epithelium
Immunoglobulins
Complementary DNA
Proteins
Epithelium
5 Citations (Scopus)

In vivo gene transfer as a means to study the physiology and morphogenesis of the retinal pigment epithelium in the rat

Marmorstein, A. D., Peachey, N. S. & Csaky, K. G., Jul 1 2003, In : Methods. 30, 3, p. 277-285 9 p.

Research output: Contribution to journalArticle

Gene transfer
Retinal Pigments
Retinal Pigment Epithelium
Physiology
Morphogenesis
108 Citations (Scopus)

Isolation and structural studies of the intact scrapie agent protein

Bolton, D. C., Bendheim, P. E., Marmorstein, A. D. & Potempska, A., Nov 1 1987, In : Archives of Biochemistry and Biophysics. 258, 2, p. 579-590 12 p.

Research output: Contribution to journalArticle

PrPSc Proteins
Endopeptidase K
PrP 27-30 Protein
Digestion
Proteins