• 4039 Citations
  • 38 Scopus h-Index
1986 …2019
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Research Output 1987 2019

1987
108 Citations (Scopus)

Isolation and structural studies of the intact scrapie agent protein

Bolton, D. C., Bendheim, P. E., Marmorstein, A. D. & Potempska, A., Nov 1 1987, In : Archives of Biochemistry and Biophysics. 258, 2, p. 579-590 12 p.

Research output: Contribution to journalArticle

PrPSc Proteins
Endopeptidase K
PrP 27-30 Protein
Digestion
Proteins
1988
3 Citations (Scopus)

Scrapie agent proteins do not accumulate in grey tremor mice

Bendheim, P. E., Marmorstein, A. D., Potempska, A. & Bolton, D. C., 1988, In : Journal of General Virology. 69, 4, p. 961-966 6 p.

Research output: Contribution to journalArticle

PrPSc Proteins
Tremor
Proteins
Scrapie
Brain Diseases
1992
30 Citations (Scopus)

Epithelial permeability factor: A serum protein that condenses actin and opens tight junctions

Marmorstein, A. D., Mortell, K. H., Ratcliffe, D. R. & Cramer, E. B., 1992, In : American Journal of Physiology - Cell Physiology. 262, 6 31-6

Research output: Contribution to journalArticle

Tight Junctions
Actins
Blood Proteins
Permeability
Affinity chromatography
1993
15 Citations (Scopus)

Fetal bovine serum and other sera used in tissue culture increase epithelial permeability

Mortell, K. H., Marmorstein, A. D. & Cramer, E. B., 1993, In : In Vitro Cellular and Developmental Biology - Animal. 29 A, 3 I, p. 235-238 4 p.

Research output: Contribution to journalArticle

Tissue culture
Monolayers
Permeability
Acoustic impedance
Mannitol
1996

An exogenous plasma membrane protein is polarized on the apical surface of the Retinal Pigment Epithelium (RPE) in vivo and in vitro

Marmorstein, A. D., Yeaman, C., Bonilha, V. L., Anglade, E., Csaky, K. & Rodriguez-Boulan, E., Feb 15 1996, In : Investigative Ophthalmology and Visual Science. 37, 3

Research output: Contribution to journalArticle

Retinal Pigment Epithelium
Blood Proteins
Membrane Proteins
Cell Membrane
Confocal Microscopy

Apical sorting pathways in Retinal Pigment Epithelial (RPE) cells

Bonilha, V. L., Marmorstein, A. D., Sparrow, J. R. & Rodriguez-Boulan, E., Feb 15 1996, In : Investigative Ophthalmology and Visual Science. 37, 3

Research output: Contribution to journalArticle

Retinal Pigments
Epithelial Cells
trans-Golgi Network
Human Influenza
Temperature

Comparison of integrin expression between the rat Retinal Pigment Epithelium (RPE) and the RPE-J cell line

Finnemann, S., Marmorstein, A. D. & Rodriguez-Boulan, E., Feb 15 1996, In : Investigative Ophthalmology and Visual Science. 37, 3

Research output: Contribution to journalArticle

Retinal Pigment Epithelium
Integrins
Cell Line
Western Blotting
Integrin alpha Chains

The human retinal pigment epithelial cell line ARPE-19 is polarized

Dunn, K. C., Marmorstein, A. D., Bonilha, V. L., Cohen-Gould, L., Yeaman, C., Rodriguez-Boulan, E. & Hjelmeland, L. M., Feb 15 1996, In : Investigative Ophthalmology and Visual Science. 37, 3

Research output: Contribution to journalArticle

Retinal Pigments
Epithelial Cells
Cell Line
Staining and Labeling
Ruthenium Red
42 Citations (Scopus)

The polarity of the plasma membrane protein RET-PE2 in retinal pigment epithelium is developmentally regulated

Marmorstein, A. D., Bonilha, V. L., Chiflet, S., Neill, J. M. & Rodriguez-Boulan, E., Dec 1996, In : Journal of Cell Science. 109, 13, p. 3025-3034 10 p.

Research output: Contribution to journalArticle

Retinal Pigment Epithelium
Blood Proteins
Membrane Proteins
Cell Membrane
Biotinylation
1997
32 Citations (Scopus)

Apical sorting of influenza hemagglutinin by transcytosis in retinal pigment epithelium

Bonilha, V. L., Marmorstein, A. D., Cohen-Gould, L. & Rodriguez-Boulan, E., Aug 1997, In : Journal of Cell Science. 110, 15, p. 1717-1727 11 p.

Research output: Contribution to journalArticle

Transcytosis
Retinal Pigment Epithelium
Vesicular Stomatitis
Hemagglutinins
Human Influenza
25 Citations (Scopus)

Identification of the retinal pigment epithelium protein RET-PE2 as CE- 9/OX-47, a member of the immunoglobulin superfamily

Finnemann, S. C., Marmorstein, A. D., Neill, J. M. & Rodriguez-Boulan, E., Oct 1997, In : Investigative Ophthalmology and Visual Science. 38, 11, p. 2366-2374 9 p.

Research output: Contribution to journalArticle

Retinal Pigment Epithelium
Immunoglobulins
Complementary DNA
Proteins
Epithelium
1 Citation (Scopus)

P75-NTR is sorted apically in I-.PE cells independent of the maturation of the apical surface

Marmorstein, A. D., Bonilha, V. L., Yeaman, C., Finnemann, S. & Rodriguez-Boulan, E., 1997, In : Investigative Ophthalmology and Visual Science. 38, 4

Research output: Contribution to journalArticle

Membranes
Protein Transport
Microvilli
Adenoviridae
Proteins
269 Citations (Scopus)

Phagocytosis of rod outer segments by retinal pigment epithelial cells requires αvβ5 integrin for binding but not for internalization

Finnemann, S. C., Bonilha, V. L., Marmorstein, A. D. & Rodriguez-Boulan, E., Nov 25 1997, In : Proceedings of the National Academy of Sciences of the United States of America. 94, 24, p. 12932-12937 6 p.

Research output: Contribution to journalArticle

Rod Cell Outer Segment
Retinal Pigments
Phagocytosis
Integrins
Epithelial Cells
1998
42 Citations (Scopus)

Apical polarity of N-CAM and EMMPRIN in retinal pigment epithelium resulting from suppression of basolateral signal recognition

Marmorstein, A. D., Gan, Y. C., Bonilha, V. L., Finnemann, S. C., Csaky, K. G. & Rodriguez-Boulan, E., Aug 10 1998, In : Journal of Cell Biology. 142, 3, p. 697-710 14 p.

Research output: Contribution to journalArticle

CD147 Antigens
Retinal Pigments
Retinal Pigment Epithelium
Epithelial Cells
Nerve Growth Factor Receptor
66 Citations (Scopus)

Morphogenesis of the retinal pigment epithelium: Toward understanding retinal degenerative diseases

Marmorstein, A. D., Finnemann, S. C., Bonilha, V. L. & Rodriguez-Boulan, E., 1998, In : Annals of the New York Academy of Sciences. 857, p. 1-12 12 p.

Research output: Contribution to journalArticle

Retinal Diseases
Retinal Pigments
Retinal Pigment Epithelium
Morphogenesis
Proteins
97 Citations (Scopus)

Use of the ARPE-19 cell line as a model of RPE polarity: Basolateral secretion of FGF5

Dunn, K. C., Marmorstein, A. D., Bonilha, V. L., Rodriguez-Boulan, E., Giordano, F. & Hjelmeland, L. M., Dec 1998, In : Investigative Ophthalmology and Visual Science. 39, 13, p. 2744-2749 6 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor 5
Retinal Pigment Epithelium
LDL Receptors
Cell Line
Hemagglutinins
1999
177 Citations (Scopus)

Caveolin-2 localizes to the Golgi complex but redistributes to plasma membrane, caveolae, and rafts when co-expressed with caveolin-1

Mora, R., Bonilha, V. L., Marmorstein, A. D., Scherer, P. E., Brown, D., Lisanti, M. P. & Rodriguez-Boulan, E., Sep 3 1999, In : Journal of Biological Chemistry. 274, 36, p. 25708-25717 10 p.

Research output: Contribution to journalArticle

Caveolin 2
Caveolin 1
Caveolae
Golgi Apparatus
Cell membranes
45 Citations (Scopus)

Retina-specific nuclear receptor: A potential regulator of cellular retinaldehyde-binding protein expressed in retinal pigment epithelium and Muller glial cells

Chen, F., Figueroa, D. J., Marmorstein, A. D., Zhang, Q., Petrukhin, K., Thomas Caskey, C. & Austin, C. P., Dec 21 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 26, p. 15149-15154 6 p.

Research output: Contribution to journalArticle

Retinaldehyde
Ependymoglial Cells
Retinal Pigment Epithelium
Cytoplasmic and Nuclear Receptors
Neuroglia
2000
292 Citations (Scopus)

Bestrophin, the product of the Best vitelliform macular dystrophy gene (VMD2), localizes to the basolateral plasma membrane of the retinal pigment epithelium

Marmorstein, A. D., Marmorstein, L. Y., Rayborn, M., Wang, X., Hollyfield, J. G. & Petrukhin, K., Nov 7 2000, In : Proceedings of the National Academy of Sciences of the United States of America. 97, 23, p. 12758-12763 6 p.

Research output: Contribution to journalArticle

Vitelliform Macular Dystrophy
Retinal Pigment Epithelium
Cell Membrane
Electrooculography
Genes
191 Citations (Scopus)

Kinesin and dynamin are required for post-Golgi transport of a plasma-membrane protein

Kreitzer, G., Marmorstein, A. D., Okamoto, P., Vallee, R. & Rodriguez-Boulan, E., 2000, In : Nature Cell Biology. 2, 2, p. 125-127 3 p.

Research output: Contribution to journalArticle

Biological Transport
Dynamins
Nerve Growth Factor Receptors
Kinesin
Cell Polarity
54 Citations (Scopus)

Saturation of, and competition for entry into, the apical secretory pathway

Marmorstein, A. D., Csaky, K. G., Baffi, J., Lam, L., Rahaal, F. & Rodriguez-Boulan, E., Mar 28 2000, In : Proceedings of the National Academy of Sciences of the United States of America. 97, 7, p. 3248-3253 6 p.

Research output: Contribution to journalArticle

Secretory Pathway
Transforming Growth Factors
Protein Transport
Tunicamycin
Transgenes
2001
42 Citations (Scopus)

Oxidized low density lipoprotein-induced inhibition of processing of photoreceptor outer segments by RPE

Hoppe, G., Marmorstein, A. D., Pennock, E. A. & Hoff, H. F., 2001, In : Investigative Ophthalmology and Visual Science. 42, 11, p. 2714-2720 7 p.

Research output: Contribution to journalArticle

Retinal Pigments
Rhodopsin
Phagosomes
Epithelial Cells
Cathepsin D
33 Citations (Scopus)

Proteome survey of proliferating and differentiating rat RPE-J cells

West, K. A., Yan, L., Miyagi, M., Crabb, J. S., Marmorstein, A. D., Marmorstein, L. Y. & Crabb, J. W., 2001, In : Experimental Eye Research. 73, 4, p. 479-491 13 p.

Research output: Contribution to journalArticle

Proteome
Proteins
Growth
Gels
Retinaldehyde
82 Citations (Scopus)

The polarity of the retinal pigment epithelium

Marmorstein, A. D., 2001, In : Traffic. 2, 12, p. 867-872 6 p.

Research output: Contribution to journalArticle

Retinal Pigments
Retinal Pigment Epithelium
Gene therapy
Retinal Diseases
Transplants
2002
142 Citations (Scopus)

Aberrant accumulation of EFEMP1 underlies drusen formation in Malattia Leventinese and age-related macular degeneration

Marmorstein, L. Y., Munier, F. L., Arsenijevic, Y., Schorderet, D. F., McLaughlin, P. J., Chung, D., Traboulsi, E. & Marmorstein, A. D., Oct 1 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 20, p. 13067-13072 6 p.

Research output: Contribution to journalArticle

Macular Degeneration
Retinal Pigment Epithelium
Retinal Drusen
Bruch Membrane
Mutant Proteins
61 Citations (Scopus)

Bestrophin interacts physically and functionally with protein phosphatase 2A

Marmorstein, L. Y., McLaughlin, P. J., Brett Stanton, J., Yan, L., Crabb, J. W. & Marmorstein, A. D., Aug 23 2002, In : Journal of Biological Chemistry. 277, 34, p. 30591-30597 7 p.

Research output: Contribution to journalArticle

Protein Phosphatase 2
Phosphorylation
Retinal Pigments
Electrooculography
Epithelial Cells
19 Citations (Scopus)

Noninvasive recording and response characteristics of the rat dc-electroretinogram

Peachey, N. S., Stanton, J. B. & Marmorstein, A. D., Nov 2002, In : Visual Neuroscience. 19, 6, p. 693-701 9 p.

Research output: Contribution to journalArticle

Electrooculography
Retinal Pigment Epithelium
Electrodes
Light
Vitelliform Macular Dystrophy
25 Citations (Scopus)

Retinal pigment epithelial cells exhibit unique expression and localization of plasma membrane syntaxins which may contribute to their trafficking phenotype

Low, S. H., Marmorstein, L. Y., Miura, M., Li, X., Kudo, N., Marmorstein, A. D. & Weimbs, T., Dec 1 2002, In : Journal of Cell Science. 115, 23, p. 4545-4553 9 p.

Research output: Contribution to journalArticle

Qa-SNARE Proteins
Retinal Pigments
SNARE Proteins
Epithelial Cells
Cell Membrane
110 Citations (Scopus)

Spectral profiling of autofluorescence associated with lipofuscin, Bruch's membrane, and sub-RPE deposits in normal and AMD eyes

Marmorstein, A. D., Marmorstein, L. Y., Sakaguchi, H. & Hollyfield, J. G., 2002, In : Investigative Ophthalmology and Visual Science. 43, 7, p. 2435-2441 7 p.

Research output: Contribution to journalArticle

Bruch Membrane
Lipofuscin
Retinal Pigment Epithelium
Macular Degeneration
Animal Models
2003
72 Citations (Scopus)

Expression and localization of bestrophin during normal mouse development

Bakall, B., Marmorstein, L. Y., Hoppe, G., Peachey, N. S., Wadelius, C. & Marmorstein, A. D., Aug 1 2003, In : Investigative Ophthalmology and Visual Science. 44, 8, p. 3622-3628 7 p.

Research output: Contribution to journalArticle

Retinal Pigment Epithelium
Electroretinography
Messenger RNA
Light Signal Transduction
Proteins
5 Citations (Scopus)

In vivo gene transfer as a means to study the physiology and morphogenesis of the retinal pigment epithelium in the rat

Marmorstein, A. D., Peachey, N. S. & Csaky, K. G., Jul 1 2003, In : Methods. 30, 3, p. 277-285 9 p.

Research output: Contribution to journalArticle

Gene transfer
Retinal Pigments
Retinal Pigment Epithelium
Physiology
Morphogenesis
49 Citations (Scopus)

Protein database, human retinal pigment epithelium.

West, K. A., Yan, L., Shadrach, K., Sun, J., Hasan, A., Miyagi, M., Crabb, J. S., Hollyfield, J. G., Marmorstein, A. D. & Crabb, J. W., Jan 2003, In : Molecular & cellular proteomics : MCP. 2, 1, p. 37-49 13 p.

Research output: Contribution to journalArticle

Protein Databases
Retinal Pigments
Retinal Pigment Epithelium
Mass spectrometry
Proteolysis
2004
45 Citations (Scopus)

A model of best vitelliform macular dystrophy in rats

Marmorstein, A. D., Stanton, J. B., Yocom, J., Bakall, B., Schiavone, M. T., Wadelius, C., Marmorstein, L. Y. & Peachey, N. S., Oct 2004, In : Investigative Ophthalmology and Visual Science. 45, 10, p. 3733-3739 7 p.

Research output: Contribution to journalArticle

Vitelliform Macular Dystrophy
Light
Retinal Pigments
Cell Membrane
Fluorescence Microscopy
33 Citations (Scopus)

Contribution of Kir4.1 to the mouse electroretinogram

Wu, J., Marmorstein, A. D., Kofuji, P. & Peachey, N. S., Sep 1 2004, In : Molecular Vision. 10, p. 650-654 5 p.

Research output: Contribution to journalArticle

Retinal Pigment Epithelium
Dark Adaptation
Light
Cornea
Polymerase Chain Reaction
46 Citations (Scopus)

Light-Evoked Responses of the Mouse Retinal Pigment Epithelium

Wu, J., Peachey, N. S. & Marmorstein, A. D., Mar 2004, In : Journal of Neurophysiology. 91, 3, p. 1134-1142 9 p.

Research output: Contribution to journalArticle

Retinal Pigment Epithelium
Light
Transducin
Light Signal Transduction
Retinal Rod Photoreceptor Cells
2005

Application of ratiometry to fundus autofluorescence imaging

Marmorstein, A. D., 2005, Optics InfoBase Conference Papers. Optical Society of America

Research output: Chapter in Book/Report/Conference proceedingConference contribution

blindness
degeneration
Imaging techniques
causes
37 Citations (Scopus)

Tubby-like protein 1 (TULP1) interacts with F-actin in photoreceptor cells

Xi, Q., Pauer, G. J. T., Marmorstein, A. D., Crabb, J. W. & Hagstrom, S. A., Dec 2005, In : Investigative Ophthalmology and Visual Science. 46, 12, p. 4754-4761 8 p.

Research output: Contribution to journalArticle

Photoreceptor Cells
Actins
Proteins
Protein Binding
Cilia
2006
1 Citation (Scopus)

Cell Surface Biotinylation and Other Techniques for Determination of Surface Polarity of Epithelial Monolayers

Deora, A., Chatterjee, S., Marmorstein, A. D., Zurzolo, C., Le Bivic, A. & Rodriguez-Boulan, E., 2006, Cell Biology, Four-Volume Set. Elsevier Inc., Vol. 2. p. 241-249 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Biotinylation
Monolayers
Membrane Proteins
Biotin
Starvation
150 Citations (Scopus)

Expression of bestrophin-1, the product of the VMD2 gene, modulates voltage-dependent Ca2+ channels in retinal pigment epithelial cells

Rosenthal, R., Bakall, B., Kinnick, T., Peachey, N., Wimmers, S., Wadelius, C., Marmorstein, A. D. & Strauss, O., Jan 2006, In : FASEB Journal. 20, 1, p. 178-180 3 p.

Research output: Contribution to journalArticle

chloride channels
protein transport
gene expression regulation
ion transport
epithelial cells
18 Citations (Scopus)

Functional abnormalities in the retinal pigment epithelium of CFTR mutant mice

Wu, J., Marmorstein, A. D. & Peachey, N. S., Aug 2006, In : Experimental Eye Research. 83, 2, p. 424-428 5 p.

Research output: Contribution to journalArticle

Retinal Pigment Epithelium
Cystic Fibrosis
Light
Ion Channels
Mutation
38 Citations (Scopus)

Hydrodynamic properties of porcine bestrophin-1 in Triton X-100

Stanton, J. B., Goldberg, A. F. X., Hoppe, G., Marmorstein, L. Y. & Marmorstein, A. D., Feb 2006, In : Biochimica et Biophysica Acta - Biomembranes. 1758, 2, p. 241-247 7 p.

Research output: Contribution to journalArticle

Octoxynol
Hydrodynamics
Stoichiometry
Gel Chromatography
Swine
133 Citations (Scopus)

Targeted disruption of fibulin-4 abolishes elastogenesis and causes perinatal lethality in mice

McLaughlin, P. J., Chen, Q., Horiguchi, M., Starcher, B. C., Stanton, J. B., Broekelmann, T. J., Marmorstein, A. D., McKay, B., Mecham, R., Nakamura, T. & Marmorstein, L. Y., Mar 2006, In : Molecular and Cellular Biology. 26, 5, p. 1700-1709 10 p.

Research output: Contribution to journalArticle

Elastic Tissue
Elastin
Tropoelastin
Elasticity
Desmosine
134 Citations (Scopus)

The light peak of the electroretinogram is dependent on voltage-gated calcium channels and antagonized by bestrophin (best-1)

Marmorstein, L. Y., Wu, J., McLaughlin, P., Yocom, J., Karl, M. O., Neussert, R., Wimmers, S., Stanton, J. B., Gregg, R. G., Strauss, O., Peachey, N. S. & Marmorstein, A. D., May 2006, In : Journal of General Physiology. 127, 5, p. 577-589 13 p.

Research output: Contribution to journalArticle

Calcium Channels
Vitelliform Macular Dystrophy
Light
Electrooculography
Nimodipine
2007
67 Citations (Scopus)

Enhanced accumulation of A2E in individuals homozygous or heterozygous for mutations in BEST1 (VMD2)

Bakall, B., Radu, R. A., Stanton, J. B., Burke, J. M., McKay, B. S., Wadelius, C., Mullins, R. F., Stone, E. M., Travis, G. H. & Marmorstein, A. D., Jul 2007, In : Experimental Eye Research. 85, 1, p. 34-43 10 p.

Research output: Contribution to journalArticle

Vitelliform Macular Dystrophy
Lipofuscin
Mutation
Retinal Pigment Epithelium
Heterozygote
33 Citations (Scopus)

Focus on Molecules: Bestrophin (Best-1)

Marmorstein, A. D. & Kinnick, T. R., Oct 2007, In : Experimental Eye Research. 85, 4, p. 423-424 2 p.

Research output: Contribution to journalArticle

Eye Proteins
Electrooculography
Electroretinography
Lipofuscin
Retinal Degeneration
71 Citations (Scopus)

Formation and progression of sub-retinal pigment epithelium deposits in Efemp1 mutation knock-in mice: A model for the early pathogenic course of macular degeneration

Marmorstein, L. Y., McLaughlin, P. J., Peachey, N. S., Sasaki, T. & Marmorstein, A. D., Oct 15 2007, In : Human Molecular Genetics. 16, 20, p. 2423-2432 10 p.

Research output: Contribution to journalArticle

Retinal Pigment Epithelium
Macular Degeneration
Mutation
Bruch Membrane
Blindness
72 Citations (Scopus)

Lack of fibulin-3 causes early aging and herniation, but not macular degeneration in mice

McLaughlin, P. J., Bakall, B., Choi, J., Liu, Z., Sasaki, T., Davis, E. C., Marmorstein, A. D. & Marmorstein, L. Y., Dec 15 2007, In : Human Molecular Genetics. 16, 24, p. 3059-3070 12 p.

Research output: Contribution to journalArticle

Macular Degeneration
Fascia
Xiphoid Bone
Hernia
Connective Tissue
24 Citations (Scopus)

The challenge of modeling macular degeneration in mice

Marmorstein, A. D. & Marmorstein, L. Y., May 2007, In : Trends in Genetics. 23, 5, p. 225-231 7 p.

Research output: Contribution to journalArticle

Macular Degeneration
Mammals
43 Citations (Scopus)

Voltage-dependent calcium channel CaV1.3 subunits regulate the light peak of the electroretinogram

Wu, J., Marmorstein, A. D., Striessnig, J. & Peachey, N. S., May 2007, In : Journal of Neurophysiology. 97, 5, p. 3731-3735 5 p.

Research output: Contribution to journalArticle

Calcium Channels
Light
Retinal Pigment Epithelium
Retinal Rod Photoreceptor Cells
Nimodipine
2008
43 Citations (Scopus)

Bestrophin-2 is involved in the generation of intraocular pressure

Bakall, B., McLaughlin, P., Stanton, J. B., Zhang, Y., Hartzell, H. C., Marmorstein, L. Y. & Marmorstein, A. D., Apr 2008, In : Investigative Ophthalmology and Visual Science. 49, 4, p. 1563-1570 8 p.

Research output: Contribution to journalArticle

Intraocular Pressure
Epithelium
Colon
Exons
Staining and Labeling