• 10343 Citations
  • 57 Scopus h-Index
1976 …2020
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Research Output 1988 2019

2019

Anorectal pressures measured with high-resolution manometry in healthy people—Normal values and asymptomatic pelvic floor dysfunction

Oblizajek, N. R., Gandhi, S., Sharma, M., Chakraborty, S., Muthyala, A., Prichard, D., Feuerhak, K. & Bharucha, A. E., Jan 1 2019, In : Neurogastroenterology and Motility. e13597.

Research output: Contribution to journalArticle

Pelvic Floor
Manometry
Pressure
Reference Values
Fecal Incontinence

A Practical Guide to Biofeedback Therapy for Pelvic Floor Disorders

Narayanan, S. P. & Bharucha, A. E., May 1 2019, In : Current gastroenterology reports. 21, 5, 21.

Research output: Contribution to journalReview article

Pelvic Floor Disorders
Fecal Incontinence
Therapeutics
Defecation
Controlled Clinical Trials

Association between allelic variants in the glucagon-like peptide 1 and cholecystokinin receptor genes with gastric emptying and glucose tolerance

Anderson, B., Carlson, P., Laurenti, M., Vella, A., Camilleri, M., Desai, A., Feuerhak, K. & Bharucha, A. E., Jan 1 2019, (Accepted/In press) In : Neurogastroenterology and Motility. e13724.

Research output: Contribution to journalArticle

Cholecystokinin Receptors
Gastric Emptying
T Cell Transcription Factor 1
Glucose
Glucagon-Like Peptide 1
5 Citations (Scopus)

Chronic Constipation

Bharucha, A. E. & Wald, A., Nov 2019, In : Mayo Clinic proceedings. 94, 11, p. 2340-2357 18 p.

Research output: Contribution to journalReview article

Open Access
Constipation
Laxatives
Opiate Alkaloids
Primary Care Physicians
Health Expenditures
1 Citation (Scopus)

Comparison of changes in rectal area and volume during MR evacuation proctography in healthy and constipated adults

Puthanmadhom Narayanan, S., Sharma, M., Fletcher, J. G., Karwoski, R. A., Holmes, D. R. & Bharucha, A. E., Jan 1 2019, In : Neurogastroenterology and Motility. e13608.

Research output: Contribution to journalArticle

Magnetic Resonance Spectroscopy
Rectocele
Software
Gels
3 Citations (Scopus)

Diabetic Gastroparesis

Bharucha, A. E., Kudva, Y. C. & Prichard, D. O., Oct 1 2019, In : Endocrine reviews. 40, 5, p. 1318-1352 35 p.

Research output: Contribution to journalArticle

Gastroparesis
Gastric Emptying
Dyspepsia
Ghrelin Receptor
Gastric Outlet Obstruction
2 Citations (Scopus)
Adrenergic Antagonists
Habits
Placebos
Pressure
Constipation

Effects of psychosensory stimulation on anal pressures: Effects of alfuzosin

Muthyala, A., Feuerhak, K. J., Harmsen, W. S., Chakraborty, S., Bailey, K. R. & Bharucha, A. E., Jan 1 2019, In : Neurogastroenterology and Motility. e13618.

Research output: Contribution to journalArticle

Pressure
Stroop Test
Placebos
alfuzosin
Intelligence Tests
1 Citation (Scopus)

First translational consensus on terminology and definitions of colonic motility in animals and humans studied by manometric and other techniques

Corsetti, M., Costa, M., Bassotti, G., Bharucha, A. E., Borrelli, O., Dinning, P., Di Lorenzo, C., Huizinga, J. D., Jimenez, M., Rao, S., Spiller, R., Spencer, N. J., Lentle, R., Pannemans, J., Thys, A., Benninga, M. & Tack, J., Jan 1 2019, In : Nature Reviews Gastroenterology and Hepatology.

Research output: Contribution to journalReview article

Open Access
Terminology
Animal Models
Manometry
Pediatrics
Therapeutics
3 Citations (Scopus)

GI Dysfunctions in Diabetic Gastroenteropathy, Their Relationships With Symptoms, and Effects of a GLP-1 Antagonist

Chakraborty, S., Halland, M., Burton, D., Desai, A., Neja, B., Low, P. A., Singer, W., Camilleri, M., Zinsmeister, A. R. & Bharucha, A. E., Jun 1 2019, In : The Journal of clinical endocrinology and metabolism. 104, 6, p. 1967-1977 11 p.

Research output: Contribution to journalArticle

Gastric Emptying
Lipids
Peptides
Small Intestine
Medical problems
2 Citations (Scopus)

More movement with evaluating colonic transit in humans

Bharucha, A. E., Anderson, B. & Bouchoucha, M., Feb 1 2019, In : Neurogastroenterology and Motility. 31, 2, e13541.

Research output: Contribution to journalReview article

Capsules
Electromagnetic Phenomena
Pressure
Radionuclide Imaging
Colon
1 Citation (Scopus)

Relationship between symptoms during a gastric emptying study and intestinal chemosensitivity with daily symptoms

Chakraborty, S., Desai, A., Halland, M., Burton, D., Camilleri, M., Zinsmeister, A. R. & Bharucha, A. E., Jan 1 2019, In : Neurogastroenterology and Motility. e13686.

Research output: Contribution to journalArticle

Gastric Emptying
Dyspepsia
Lipids
Glucagon-Like Peptide 1
Symptom Assessment

The international anorectal physiology working group (IAPWG) recommendations: Standardized testing protocol and the London classification for disorders of anorectal function

All members of the International Anorectal Physiology Working Group, Jan 1 2019, (Accepted/In press) In : Neurogastroenterology and Motility. e13679.

Research output: Contribution to journalArticle

Open Access
Rectal Diseases
Consensus
Manometry
Gastroenterology
Ataxia

Utility of the plasma pancreatic polypeptide response to modified sham feeding in diabetic gastroenteropathy and non-ulcer dyspepsia

Desai, A., Low, P. A., Camilleri, M., Singer, W., Burton, D., Chakraborty, S. & Bharucha, A. E., Jan 1 2019, (Accepted/In press) In : Neurogastroenterology and Motility. e13744.

Research output: Contribution to journalArticle

Pancreatic Polypeptide
Dyspepsia
Gastric Emptying
Hyperglycemia
2018
4 Citations (Scopus)

Aging, Obesity, and the Incidence of Diverticulitis: A Population-Based Study

Lee, T. H., Setty, P. T., Parthasarathy, G., Bailey, K. R., Wood-Wentz, C. M., Fletcher, J. G., Takahashi, N. M., Khosla, S., Moynagh, M. R., Zinsmeister, A. R. & Bharucha, A. E., Sep 1 2018, In : Mayo Clinic Proceedings. 93, 9, p. 1256-1265 10 p.

Research output: Contribution to journalArticle

Diverticulitis
Obesity
Incidence
Body Mass Index
Population
1 Citation (Scopus)

A pharmacological challenge predicts reversible rectal sensorimotor dysfunctions in women with fecal incontinence

Sharma, M., Feuerhak, K., Zinsmeister, A. R. & Bharucha, A. E., Oct 1 2018, In : Neurogastroenterology and Motility. 30, 10, e13383.

Research output: Contribution to journalArticle

Fecal Incontinence
Clonidine
Atropine
Pharmacology
Compliance
25 Citations (Scopus)

Expert consensus document: Advances in the evaluation of anorectal function

Carrington, E. V., Scott, S. M., Bharucha, A. E., Mion, F., Remes-Troche, J. M., Malcolm, A., Heinrich, H., Fox, M. & Rao, S. S., May 1 2018, In : Nature Reviews Gastroenterology and Hepatology. 15, 5, p. 309-325 17 p.

Research output: Contribution to journalReview article

Defecography
Fecal Incontinence
Manometry
Routine Diagnostic Tests
Ultrasonography
1 Citation (Scopus)

Neurophysiologic Mechanisms of Human Large Intestinal Motility

Bharucha, A. E. & Brookes, S. J. H., Mar 28 2018, Physiology of the Gastrointestinal Tract: Sixth Edition. Elsevier Inc., Vol. 1-2. p. 517-564 48 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Gastrointestinal Motility
Anatomy
Enteroendocrine Cells
Interstitial Cells of Cajal
Food
11 Citations (Scopus)

Normal values for assessment of anal sphincter morphology, anorectal motion, and pelvic organ prolapse with MRI in healthy women

Tirumanisetty, P., Prichard, D., Fletcher, J. G., Chakraborty, S., Zinsmeister, A. R. & Bharucha, A. E., Jan 1 2018, (Accepted/In press) In : Neurogastroenterology and Motility.

Research output: Contribution to journalArticle

Pelvic Organ Prolapse
Anal Canal
Parity
Reference Values
Defecation
2 Citations (Scopus)

Painful and Painless Constipation: All Roads Lead to (A Change in) Rome

Bharucha, A. E. & Sharma, M., Mar 21 2018, (Accepted/In press) In : Digestive Diseases and Sciences. p. 1-4 4 p.

Research output: Contribution to journalArticle

Constipation
3 Citations (Scopus)

Recent advances in understanding and managing chronic constipation

Prichard, D. O. & Bharucha, A. E., Jan 1 2018, In : F1000Research. 7

Research output: Contribution to journalReview article

Constipation
Laxatives
Physiology
Health
Biofeedback
1 Citation (Scopus)

Relationship between symptoms and quality of life in fecal incontinence

Bedard, K., Heymen, S., Palsson, O. S., Bharucha, A. E. & Whitehead, W. E., Mar 1 2018, In : Neurogastroenterology and Motility. 30, 3, e13241.

Research output: Contribution to journalArticle

Fecal Incontinence
Quality of Life
Confidence Intervals
Linear Models
Gases
6 Citations (Scopus)

Reproducibility of gastric emptying assessed with scintigraphy in patients with upper GI symptoms

Desai, A., O'Connor, M., Neja, B., Delaney, K., Camilleri, M., Zinsmeister, A. R. & Bharucha, A. E., Jan 1 2018, (Accepted/In press) In : Neurogastroenterology and Motility.

Research output: Contribution to journalArticle

Gastric Emptying
Radionuclide Imaging
Gastroparesis
Meals
Stomach

Response to Vitton et al.

Basilisco, G. & Bharucha, A. E., Jan 1 2018, In : Neurogastroenterology and Motility. 30, 1, e13226.

Research output: Contribution to journalLetter

1 Citation (Scopus)

Transforming the Activation of Clinical Trials

Watters, J. T., Pitzen, J. H., Sanders, L. J., Bruce, V. N. M., Cornell, A. R., Cseko, G. C., Grace, J. S., Kwon, P. S., Kukla, A. K., Lee, M. S., Monosmith, M. D., Myren, J. D., Kottschade, R. S., Shaft, M. N., Weis, J. J. A., Welter, J. C. & Bharucha, A. E., Jan 1 2018, In : Clinical Pharmacology and Therapeutics. 103, 1, p. 43-46 4 p.

Research output: Contribution to journalArticle

National Academies of Science, Engineering, and Medicine (U.S.) Health and Medicine Division
Clinical Trials
United States Food and Drug Administration
Therapeutics
4 Citations (Scopus)

When all seems lost: management of refractory constipation—Surgery, rectal irrigation, percutaneous endoscopic colostomy, and more

Wilkinson-Smith, V., Bharucha, A. E., Emmanuel, A., Knowles, C., Yiannakou, Y. & Corsetti, M., May 1 2018, In : Neurogastroenterology and Motility. 30, 5, e13352.

Research output: Contribution to journalReview article

Colostomy
Constipation
Pharmacology
Therapeutics
2017
5 Citations (Scopus)

Assessing the colonic microbiome, hydrogenogenic and hydrogenotrophic genes, transit and breath methane in constipation

Wolf, P. G., Parthasarathy, G., Chen, J., O'Connor, H. M., Chia, N. D., Bharucha, A. E. & Rex Gaskins, H., 2017, (Accepted/In press) In : Neurogastroenterology and Motility.

Research output: Contribution to journalArticle

Microbiota
Methane
Constipation
Hydrogensulfite Reductase
Genes
3 Citations (Scopus)
Manometry
Constipation
Catheters
Flatulence
Pressure
1 Citation (Scopus)
Microbiota
MicroRNAs
Diet
Pharmaceutical Preparations
Therapeutics
6 Citations (Scopus)

Existing and emerging therapies for managing constipation and diarrhea

Bharucha, A. E., Wouters, M. M. & Tack, J., Dec 1 2017, In : Current Opinion in Pharmacology. 37, p. 158-166 9 p.

Research output: Contribution to journalReview article

Constipation
Diarrhea
rifaximin
Serotonin 5-HT4 Receptor Agonists
Loperamide
14 Citations (Scopus)

High-resolution anorectal manometry: An expensive hobby or worth every penny?

Basilisco, G. & Bharucha, A. E., Aug 1 2017, In : Neurogastroenterology and Motility. 29, 8, e13125.

Research output: Contribution to journalReview article

Hobbies
Manometry
American Medical Association
Rectal Diseases
Catheters
21 Citations (Scopus)

Hyperglycemia Increases Interstitial Cells of Cajal via MAPK1 and MAPK3 Signaling to ETV1 and KIT, Leading to Rapid Gastric Emptying

Hayashi, Y., Toyomasu, Y., Saravanaperumal, S. A., Bardsley, M. R., Smestad, J. A., Lorincz, A., Eisenman, S. T., Cipriani, G., Nelson Holte, M. H., Al Khazal, F. J., Syed, S. A., Gajdos, G. B., Choi, K. M., Stoltz, G. J., Miller, K. E., Kendrick, M. L., Rubin, B. P., Gibbons, S. J., Bharucha, A. E., Linden, D. R. & 3 others, Maher III, L. J., Farrugia, G. & Ordog, T., Aug 1 2017, In : Gastroenterology. 153, 2, p. 521-535.e20

Research output: Contribution to journalArticle

Interstitial Cells of Cajal
Gastric Emptying
Mitogen-Activated Protein Kinase 1
Hyperglycemia
Cell Lineage
21 Citations (Scopus)

Methods of anorectal manometry vary widely in clinical practice: Results from an international survey

The International Anorectal Physiology Working Party Group (IAPWG), Aug 1 2017, In : Neurogastroenterology and Motility. 29, 8, e13016.

Research output: Contribution to journalArticle

Manometry
Guidelines
Technology
Surveys and Questionnaires
Pressure
5 Citations (Scopus)

Purification of nanogram-range immunoprecipitated DNA in ChIP-seq application

Zhong, J., Ye, Z., Lenz, S. W., Clark, C. R., Bharucha, A. E., Farrugia, G., Robertson, K. D., Zhang, Z., Ordog, T. & Lee, J. H., Dec 21 2017, In : BMC Genomics. 18, 1, 985.

Research output: Contribution to journalArticle

Chromatin Immunoprecipitation
DNA
Gene Library
Libraries
Buffers
16 Citations (Scopus)
Gastric Emptying
Medical problems
Type 1 Diabetes Mellitus
Glucose
Erythromycin
5 Citations (Scopus)

Reproducibility of assessing fecal microbiota in chronic constipation

Parthasarathy, G., Chen, J., Chia, N. D., O'Connor, H. M., Gaskins, H. R. & Bharucha, A. E., 2017, (Accepted/In press) In : Neurogastroenterology and Motility.

Research output: Contribution to journalArticle

Microbiota
Constipation
Healthy Volunteers
Laxatives
Energy Intake
8 Citations (Scopus)

Surgical Interventions and the Use of Device-Aided Therapy for the Treatment of Fecal Incontinence and Defecatory Disorders

Bharucha, A. E., Rao, S. S. C. & Shin, A. S., Dec 1 2017, In : Clinical Gastroenterology and Hepatology. 15, 12, p. 1844-1854 11 p.

Research output: Contribution to journalArticle

Fecal Incontinence
Practice Guidelines
Equipment and Supplies
Therapeutics
Colostomy
2016
13 Citations (Scopus)

Anorectal and Pelvic Pain

Bharucha, A. E. & Lee, T. H., Oct 1 2016, In : Mayo Clinic Proceedings. 91, 10, p. 1471-1486 16 p.

Research output: Contribution to journalReview article

Interstitial Cystitis
Pelvic Pain
Chronic Pain
Urinary Bladder
Rectal Diseases
89 Citations (Scopus)

Anorectal disorders

Rao, S. S. C., Bharucha, A. E., Chiarioni, G., Felt-Bersma, R., Knowles, C., Malcolm, A. & Wald, A., May 1 2016, In : Gastroenterology. 150, 6, p. 1430-1442e4

Research output: Contribution to journalArticle

Rectal Diseases
Fecal Incontinence
Defecation
Pain
Pelvic Floor
2 Citations (Scopus)

Commentary

Chakraborty, S. & Bharucha, A. E., Dec 20 2016, In : Annals of Internal Medicine. 165, 12, p. JC69

Research output: Contribution to journalComment/debate

14 Citations (Scopus)

Common Functional Gastroenterological Disorders Associated With Abdominal Pain

Bharucha, A. E., Chakraborty, S. & Sletten, C. D., Aug 1 2016, In : Mayo Clinic Proceedings. 91, 8, p. 1118-1132 15 p.

Research output: Contribution to journalReview article

Abdominal Pain
Irritable Bowel Syndrome
Constipation
Opioid Analgesics
Diarrhea
4 Citations (Scopus)

Determinants and clinical impact of pressure drift in manoscan anorectal high resolution manometry system

Parthasarathy, G., McMaster, J., Feuerhak, K., Zinsmeister, A. R. & Bharucha, A. E., 2016, (Accepted/In press) In : Neurogastroenterology and Motility.

Research output: Contribution to journalArticle

Manometry
Pressure
Catheters
Hot Temperature
Body Temperature
60 Citations (Scopus)

Diagnostic accuracy study of anorectal manometry for diagnosis of dyssynergic defecation

Grossi, U., Carrington, E. V., Bharucha, A. E., Horrocks, E. J., Scott, S. M. & Knowles, C. H., Mar 1 2016, In : Gut. 65, 3, p. 447-455 9 p.

Research output: Contribution to journalArticle

Defecation
Manometry
Constipation
Healthy Volunteers
Ataxia
25 Citations (Scopus)

Diagnostic disagreement between tests of evacuatory function: a prospective study of 100 constipated patients

Palit, S., Thin, N., Knowles, C. H., Lunniss, P. J., Bharucha, A. E. & Scott, S. M., Oct 1 2016, In : Neurogastroenterology and Motility. 28, 10, p. 1589-1598 10 p.

Research output: Contribution to journalArticle

Manometry
Prospective Studies
Constipation
Therapeutics
23 Citations (Scopus)

Diaphragmatic breathing for rumination syndrome: Efficacy and mechanisms of action

Halland, M., Parthasarathy, G., Bharucha, A. E. & Katzka, D. A., Mar 1 2016, In : Neurogastroenterology and Motility. 28, 3, p. 384-391 8 p.

Research output: Contribution to journalArticle

Respiration
Esophagogastric Junction
Pressure
Upper Esophageal Sphincter
Manometry
16 Citations (Scopus)

Effect of pramlintide on postprandial glucose fluxes in type 1 diabetes

Hinshaw, L., Schiavon, M., Dadlani, V., Mallad, A., Dalla Man, C., Bharucha, A. E., Basu, R., Geske, J. R., Carter, R. E., Cobelli, C., Basu, A. & Kudva, Y. C., May 1 2016, In : Journal of Clinical Endocrinology and Metabolism. 101, 5, p. 1954-1962 9 p.

Research output: Contribution to journalArticle

Medical problems
Type 1 Diabetes Mellitus
Fluxes
Glucose
Area Under Curve
13 Citations (Scopus)

Effects of hemin on heme oxygenase-1, gastric emptying, and symptoms in diabetic gastroparesis

Bharucha, A. E., Daley, S. L., Low, P. A., Gibbons, S. J., Choi, K. M., Camilleri, M., Saw, J. J., Farrugia, G. & Zinsmeister, A. R., 2016, (Accepted/In press) In : Neurogastroenterology and Motility.

Research output: Contribution to journalArticle

Gastroparesis
Hemin
Heme Oxygenase-1
Gastric Emptying
Placebos
3 Citations (Scopus)

Evaluating the safety and the effects on colonic compliance of neostigmine during motility testing in patients with chronic constipation

Mouchli, M. A., Camilleri, M., Lee, T., Parthasarathy, G., Vijayvargiya, P., Halland, M., Acosta, A. & Bharucha, A. E., 2016, (Accepted/In press) In : Neurogastroenterology and Motility.

Research output: Contribution to journalArticle

Neostigmine
Constipation
Compliance
Safety
Vital Signs
22 Citations (Scopus)

High-resolution Anorectal Manometry for Identifying Defecatory Disorders and Rectal Structural Abnormalities in Women

Prichard, D. O., Lee, T., Parthasarathy, G., Fletcher, J. G., Zinsmeister, A. R. & Bharucha, A. E., 2016, (Accepted/In press) In : Clinical Gastroenterology and Hepatology.

Research output: Contribution to journalArticle

Rectal Diseases
Manometry
Rectal Prolapse
Prolapse
Pressure
36 Citations (Scopus)

How to perform and interpret a high-Resolution anorectal manometry test

Lee, T. H. & Bharucha, A. E., 2016, In : Journal of Neurogastroenterology and Motility. 22, 1, p. 46-59 14 p.

Research output: Contribution to journalArticle

Manometry
Catheters