Rochester, MN

Projects

Projects per year 1984 2002 2003 2004 2005 2009 2012 2014 2015 2016 2017 2018 2019 2020 2021 2025

• 1 Not started
• 206 Active
• 1000 Finished

Projects per year

Search results

• Regulation of B cell development by ABCB7

  Shapiro, V. V. S. & Shapiro, V. M.

  National Institute of Allergy and Infectious Diseases

  3/17/21 → 2/28/23

  Project: Research project

• REGULATION OF HEPATIC FIBROGENEISS BY TANGO1

  Maiers, J. L. & Maiers, J.

  National Institute of Diabetes and Digestive and Kidney Diseases

  2/5/18 → 12/31/22

  Project: Research project

  • collagen 100%
  • Procollagen 75%
  • hepatocytes 50%
  • liver 50%
  • Unfolded Protein Response 41%

• Regulation of Nutrient Homeostasis by COMMD proteins

  Billadeau, D. D. & Billadeau, D. D.

  National Institute of Diabetes and Digestive and Kidney Diseases

  8/1/16 → 2/28/23

  Project: Research project

  • Proteostasis 100%
  • Nutrients 58%
  • Cell Membrane 37%
  • Endosomes 35%
  • Copper 27%

• Relating Molecular Subgroups of Endometriosis-Associated Ovarian Cancers to Survival and Risk

  Goode, E. L. & Goode, E. L.

  National Cancer Institute

  1/13/21 → 12/31/22

  Project: Research project

• Research Education Component

  Boeve, B. F.

  National Institute on Aging

  5/1/19 → 4/30/24

  Project: Research project

• Research Partnership to Address Social Needs in Cancer Care

  Atlas, S. J., Bedrick, E. J., Berwick, M., Edwards, B. S., Engen, J. R., Larson, R. S., Leslie, K. K., Ness, S. A., Osley, M. A., Royce, M. E., Sillerud, L. O., Sillerud, L. O., Sklar, L. A., Verschraegen, C. F., Wandinger-Ness, A., Willman, C., Tomkinson, A. E., Bocklage, T. J., Hathaway, H. J., Jones, D., Prossnitz, E. R., Rabinowitz, I. & Wilson, B. S.

  National Cancer Institute

  9/26/05 → 8/31/22

  Project: Research project

• Respiratory Control in Old Age

  Sieck, G. C., Mantilla, C. B., Mantilla, C. B. & Sieck, G. C.

  National Institute on Aging

  6/1/13 → 3/31/23

  Project: Research project

• Reversing Pulmonary Fibrosis Through Dopamine D1 Receptor Agonism

  Tschumperlin, D. J.

  U.S. Army

  9/1/19 → 8/31/22

  Project: Research project

  • Dopamine D1 Receptors 100%
  • Pulmonary Fibrosis 80%
  • Idiopathic Pulmonary Fibrosis 74%
  • Lung 56%
  • Fibroblasts 45%

• Reversing Pulmonary Fibrosis Through Dopamine D1 Receptor Agonism

  Tschumperlin, D. J.

  Congressionally Directed Medical Research Programs

  1/1/18 → …

  Project: Research project

  • Dopamine D1 Receptors 100%
  • Pulmonary Fibrosis 81%
  • Idiopathic Pulmonary Fibrosis 76%
  • Lung 55%
  • Fibroblasts 46%

• REVERSING PULMONARY FIBROSIS THROUGH DOPAMINE D1 RECEPTOR AGONISM

  Tschumperlin, D. J.

  Congressionally Directed Medical Research Programs

  9/1/19 → 8/31/22

  Project: Research project

  • Pulmonary Fibrosis 100%
  • Idiopathic Pulmonary Fibrosis 91%
  • Dopamine D1 Receptors 82%
  • Fibrosis 72%
  • Fibroblasts 64%

• Role of Nuclear Pore-Regulated Mechanisms in Prostate Cancer Aggressiveness

  Rodriguez Bravo, V.

  12/1/19 → 11/30/22

  Project: Research project

  • Prostate Cancer, Hereditary, 7 100%
  • Nuclear Pore 92%
  • Nuclear Pore Complex Proteins 35%
  • Prostatic Neoplasms 27%
  • Cell Nucleus Active Transport 12%

• Role of pH-mediated metabolic reprogramming in β cell failure in Type 2 Diabetes Mellitus

  Matveyenko, A. A. V., Romero, M. F. & Romero, M. M. F.

  4/1/21 → 2/28/23

  Project: Research project

  • Cellular Reprogramming 100%
  • Type 2 Diabetes Mellitus 75%
  • Glucose 16%
  • Obesity 12%
  • Insulin 11%

• SCH: Wearable Augmented Prediction of Burnout in Nurses: A Synergy of Engineering, Bioethics, Nursing

  Athreya, A. & Bobo, W. V.

  National Institute of Nursing Research

  4/11/22 → 1/31/23

  Project: Research project

  • Psychological Burnout 100%
  • Bioethics 67%
  • Nursing 37%
  • Nurses 37%
  • Workplace 18%

• Senescent Vascular Cells as Mediators of Cognitive Decline

  Marissa, S. & Schafer, M. J.

  National Institute on Aging

  1/1/21 → 12/31/22

  Project: Research project

• ST8Sia6 expression on tumors inhibits the immune response

  Shapiro, V. M. & Shapiro, V. S.

  National Cancer Institute

  12/1/19 → 11/30/22

  Project: Research project

• Stathmin-2 and TDP-43 neurodegeneration in Alzheimer?s and multi-etiology dementias

  Josephs, K. A. & Prudencio, M.

  National Institute of Neurological Disorders and Stroke

  4/1/21 → 3/31/24

  Project: Research project

  • Stathmin 100%
  • Alzheimer Disease 78%
  • Dementia 48%
  • Frontotemporal Lobar Degeneration 40%
  • Neurofibrillary Tangles 17%

• Stories for Change (S4C): Digital Storytelling for Diabetes Self-Management among Hispanic Adults

  Wieland, M. L., Sia, I. G., Sia, I. G. & Wieland, M. L.

  National Institute of Diabetes and Digestive and Kidney Diseases

  6/19/18 → 5/31/23

  Project: Research project

• Structural biology of DNA damage response in chromatin

  Mer, G. G. & Mer, G.

  National Institute of General Medical Sciences

  5/1/20 → 2/28/23

  Project: Research project

• Structure and Function of the Acetylcholine Receptor

  Sine, S. M. & Sine, S. M.

  National Institute of Neurological Disorders and Stroke

  9/1/92 → 4/30/23

  Project: Research project

  • Cholinergic Receptors 100%
  • Biophysics 41%
  • Binding Sites 35%
  • Neurotransmitter Receptor 33%
  • Congenital Myasthenic Syndromes 29%

• Studies of mRNA Translational Regulations in Diamond Blackfan Anemia

  Hu, W.

  Congressionally Directed Medical Research Programs

  1/1/17 → …

  Project: Research project

• Studies of mRNA translational regulations in erythropoiesis

  Hu, W. & Hu, W.

  National Heart, Lung, and Blood Institute

  8/30/18 → 5/31/23

  Project: Research project

• Targeted Inhibition of DNA Repair Protein TIRR with Aptamers to Counteract Resistance of Ovarian Cancer Cells to PARP Inhibitors

  Mer, G.

  Congressionally Directed Medical Research Programs

  1/1/19 → …

  Project: Research project

  • Resistance 100%
  • Molecule 80%
  • Protein 65%
  • Drug 61%
  • Surface 27%

• Targeted Prevention of Postpartum-Related Breast Cancer (PRBC)

  Radisky, D. C., Ruddy, K. J. & Sherman, M. E.

  National Cancer Institute

  2/1/22 → 1/31/23

  Project: Research project

  • Postpartum Period 100%
  • Breast Neoplasms 60%
  • Aspirin 22%
  • Inflammation 21%
  • Breast 18%

• Targeting and eliminating senescent pre-tumor cells to prevent cancer

  Weivoda, M.

  American Federation for Aging Research

  1/1/20 → …

  Project: Research project

  • Neoplasms 100%
  • Plasmacytoma 49%
  • Phenotype 47%
  • Frailty 45%
  • Multiple Myeloma 38%

• Targeting Cellular Senescence and RAGE in Type 2 Diabetes

  Farr, J. J. N. & Farr, J.

  National Institute of Diabetes and Digestive and Kidney Diseases

  5/1/21 → 4/30/23

  Project: Research project

• Targeting Cellular Senescence to Extend Healthspan

  Khosla, S. S., Ikeno, Y., Kirkland, J. L., Khosla, S., Kirkland, J. L., LeBrasseur, N. K., Pignolo, R. J. & Robbins, P. D.

  National Institute on Aging

  6/1/19 → 1/31/23

  Project: Research project

• Targeting Fatty Acid Synthase: A mechanism-guided approach to develop a novel therapeutic intervention for drug-resistant breast cancer

  Lupu, R.

  Congressionally Directed Medical Research Programs

  1/1/15 → …

  Project: Research project

  • Fatty Acid Synthases 100%
  • Breast Neoplasms 50%
  • Trastuzumab 48%
  • Neoplasms 26%
  • taxane 26%

• Targeting Fatty Acid Synthase: A mechanism-guided approach to develop a novel therapeutic intervention for drug-resistant breast cancer

  Haddad, T. C.

  Congressionally Directed Medical Research Programs

  1/1/15 → …

  Project: Research project

  • Fatty Acid Synthases 100%
  • Breast Neoplasms 50%
  • Trastuzumab 48%
  • Neoplasms 26%
  • taxane 26%

• Targeting poly (ADP ribose) polymerase (PARP) in endometrial cancer

  Weroha, S.

  National Cancer Institute

  12/1/21 → 11/30/22

  Project: Research project

  • Endometrial Neoplasms 100%
  • Poly(ADP-ribose) Polymerases 72%
  • rucaparib 43%
  • DNA Repair-Deficiency Disorders 35%
  • Poly(ADP-ribose) Polymerase Inhibitors 32%

• Targeting Protease Activated Receptor 1 for Repair of the Injured Spinal Cord

  Scarisbrick, I. A.

  National Institute of Neurological Disorders and Stroke

  9/1/21 → 8/31/22

  Project: Research project

  • Spinal Cord Injuries 100%
  • Spinal Cord Regeneration 91%
  • PAR-1 Receptor 89%
  • Neuroprotection 87%
  • Neuroglia 73%

• Targeting Selective Gut Microbiome and Their Metabolites for Therapeutic and Pathogenic Potential in Rheumatoid Arthritis

  Taneja, V. D.

  Congressionally Directed Medical Research Programs

  1/1/14 → …

  Project: Research project

  • rheumatoid arthritis 100%
  • digestive system 55%
  • microbiome 41%
  • bacteria 38%
  • therapeutics 35%

• Targeting Synovial Sarcoma with Cancer Testis Antigen Incorporated Oncolytic Viruses

  Robinson, S.

  Congressionally Directed Medical Research Programs

  1/1/20 → …

  Project: Research project

  • Synovial Sarcoma 100%
  • Oncolytic Viruses 58%
  • Testicular Neoplasms 48%
  • Viruses 30%
  • Antigens 30%

• The FA-BRCA Pathway and Response to Platinum and PARP Inhibitors in Ovarian, Tubal and Peritoneal Carcinomas

  Haluska, P. R. J., Kaufmann, S. H. & Swisher, E. E.

  Ovarian Cancer Research Fund

  1/1/13 → …

  Project: Research project

  • Poly(ADP-ribose) Polymerase Inhibitors 100%
  • Platinum 73%
  • Carcinoma 46%
  • Ovarian Neoplasms 42%
  • Biomarkers 30%

• The GNAS1 Gene as a Regulator of Osteoblast Differentiation and Molecular Target for the Stimulation of Bone Formation

  Pignolo, R.

  American Federation for Aging Research

  1/1/02 → …

  Project: Research project

• The KAPP-Sen Tissue Mapping Center Collaborative

  Garovic, V. D., Garovic, V. D., Musi, N. & Robson, P.

  National Institute on Aging

  9/30/21 → 8/31/22

  Project: Research project

• Therapeutic ECM Resorption in Cellular Systems and Precision Cut Lung Slices.

  Tschumperlin, D. D. J. & Tschumperlin, D. J.

  National Heart, Lung, and Blood Institute

  12/15/20 → 11/30/22

  Project: Research project

• Therapeutic implication of CD38 in CLL

  Chanan Khan, A. A. & Chini, E. N.

  National Cancer Institute

  9/4/19 → 8/31/22

  Project: Research project

  • T-Lymphocytes 100%
  • B-Lymphocytes 93%
  • daratumumab 68%
  • Neoplasms 65%
  • Study Guides 57%

• Therapy Evaluation Core

  Sarkaria, J. N.

  National Cancer Institute

  9/1/21 → 8/31/22

  Project: Research project

• The role of hypoxia in venous neointimal hyperplasia in hemodialysis grafts

  Misra, S. & Misra, S. S.

  National Heart, Lung, and Blood Institute

  2/1/10 → 4/30/23

  Project: Research project

  • Renal Dialysis 100%
  • Hyperplasia 93%
  • Hypoxia 83%
  • Vascular Endothelial Growth Factor A 73%
  • Transplants 65%

• The role of microglia in neuromyelitis optica

  Wu, L., Lennon, V. A., Lennon, V. A. & Wu, L.

  6/1/20 → 4/30/23

  Project: Research project

  • Neuromyelitis Optica 100%
  • Microglia 60%
  • Astrocytes 29%
  • Immunoglobulin G 22%
  • Central Nervous System 8%

• The role of nuclear PD-L1 in breast tumor cell division, progression and therapy response

  Wang, L. M., Lou, Z., Wang, L. M. & Lou, Z. Z.

  National Cancer Institute

  3/1/20 → 2/28/23

  Project: Research project

• The Role of PTPRD as a Tumor Suppressor in Neuroblastoma Pathogenesis

  Zhu, J.

  Alex's Lemonade Stand Foundation for Childhood Cancer

  1/1/13 → …

  Project: Research project

• The Role of the Microenvironment in Barrett's Esophagus

  Abrams, J. J., Abrams, J., Iyer, P. G., Rustgi, A. A. K., Iyer, P. G., Wang, K. K. K., Wang, K. K. N., Nakagawa, H., Rustgi, A. K., Wang, K. K. N., Wang, T. C. & Wu, G. D.

  National Cancer Institute

  9/26/11 → 10/31/22

  Project: Research project

• The Vascular, Autonomic, and Myocardial Phenotypes in Women with Myocardial Infarction due to Spontaneous Coronary Artery Dissection

  Tweet, M.

  National Heart, Lung, and Blood Institute

  9/1/21 → 8/31/22

  Project: Research project

  • Spontaneous Coronary Artery Dissection 100%
  • National Heart, Lung, and Blood Institute (U.S.) 30%
  • Myocardial Infarction 25%
  • Phenotype 23%
  • Blood Vessels 22%

• Trade-offs in human observer performance, image quality metrics, and patient dose

  McCollough, C. H.

  National Institute of Biomedical Imaging and Bioengineering

  9/20/12 → 12/31/22

  Project: Research project

  • Tomography 100%
  • Image quality 96%
  • dosage 68%
  • Imaging techniques 44%
  • performance 26%

• Transcriptomic Signatures of Influenza Vaccine Responses

  Kennedy, R. B. & Poland, G. A.

  National Institute of Allergy and Infectious Diseases

  1/17/18 → 12/31/22

  Project: Research project

  • Influenza Vaccines 100%
  • MF59 oil emulsion 64%
  • Helper-Inducer T-Lymphocytes 55%
  • Vaccines 40%
  • Innate Immunity 36%

• Translational Geroscience Network

  Kirkland, J. L., Kuchel, G. G. A., Kirkland, J. L., Kritchevsky, S. B., Kuchel, G. A., Kritchevsky, S. S. B., Tchkonia, T. & Tchkonia, T.

  National Institute on Aging

  2/1/19 → 11/30/22

  Project: Research project

• TrAstuzumab Cardiomyopathy Therapeutic Intervention with Carvedilol (TACTIC) Trial

  Herrmann, J. & Ruddy, K. J.

  National Cancer Institute

  3/1/19 → 2/28/23

  Project: Research project

  • Trastuzumab 100%
  • Carvedilol 95%
  • Cardiomyopathies 59%
  • Cardiotoxicity 27%
  • Heart 23%

• Understanding the Connection Between Traumatic Brain Injury and Alzheimer's Disease: A Population-Based Medical Record Review Analysis

  Brown, A. W.

  Congressionally Directed Medical Research Programs

  1/1/14 → …

  Project: Research project

• Understanding the Cooperation Between LMO1 and MYCN in Neuroblastoma Metastasis Using a Novel Zebrafish Model

  Zhu, J.

  Congressionally Directed Medical Research Programs

  1/1/16 → …

  Project: Research project