Rochester, MN

Projects

Projects per year 1989 2002 2009 2010 2011 2014 2015 2016 2017 2018 2019 2020 2021 2025

• 29 Not started
• 321 Active
• 971 Finished

Projects per year

Search results

• Reverse Engineering the Alveolus: From cellular to microenvironment specification during development

  Brownfield, D.

  National Heart, Lung, and Blood Institute

  8/15/19 → 7/31/22

  Project: Research project

  • Alveolar Epithelial Cells 100%
  • Cellular Microenvironment 79%
  • Stem Cells 28%
  • Adenocarcinoma of Lung 27%
  • Morphogenesis 25%

• REVERSING PULMONARY FIBROSIS THROUGH DOPAMINE D1 RECEPTOR AGONISM

  Tschumperlin, D. J.

  Congressionally Directed Medical Research Programs

  9/1/19 → 8/31/22

  Project: Research project

  • Pulmonary Fibrosis 100%
  • Idiopathic Pulmonary Fibrosis 91%
  • Dopamine D1 Receptors 82%
  • Fibrosis 72%
  • Fibroblasts 64%

• Assessment of Hepatitis C Virus (HCV) Infection Related Chronic Liver Disease with Advanced Multiparametric Magnetic Resonance Elastography (MRE)

  Yin, M.

  U.S. Army

  9/1/19 → 8/31/22

  Project: Research project

  • Elasticity Imaging Techniques 100%
  • Hepatitis 69%
  • Liver Diseases 62%
  • Hepacivirus 57%
  • Liver 46%

• The glial mechanism for electrical brain stimulation

  Wang, H., Worrell, G. A. & Wu, L.

  National Institute of Neurological Disorders and Stroke

  9/1/19 → 7/31/22

  Project: Research project

  • Extracellular Vesicles 100%
  • Deep Brain Stimulation 82%
  • Neuroglia 59%
  • Astrocytes 26%
  • Electric Stimulation 25%

• The Pro-Tumor Immunologic Niche of the Liver

  Ilyas, S. & Rizvi, S.

  National Cancer Institute

  9/1/19 → 8/31/22

  Project: Research project

  • Cholangiocarcinoma 100%
  • Macrophages 47%
  • Liver 39%
  • Ligands 39%
  • Apoptosis 33%

• Reversing Pulmonary Fibrosis Through Dopamine D1 Receptor Agonism

  Tschumperlin, D. J.

  U.S. Army

  9/1/19 → 8/31/22

  Project: Research project

  • Dopamine D1 Receptors 100%
  • Pulmonary Fibrosis 80%
  • Idiopathic Pulmonary Fibrosis 74%
  • Lung 56%
  • Fibroblasts 45%

• ASSESSMENT OF HEPATITIS C VIRUS (HCV) INFECTION RELATED CHRONIC LIVER DISEASE WITH ADVANCED MULTIPARAMETRIC MAGNETIC RESONANCE ELASTOGRAPHY (MRE)

  Yin, M.

  Congressionally Directed Medical Research Programs

  9/1/19 → 8/31/22

  Project: Research project

  • Elasticity Imaging Techniques 100%
  • Hepatocellular Carcinoma 66%
  • Hepacivirus 65%
  • Liver Diseases 46%
  • Hepatitis 44%

• Therapeutic implication of CD38 in CLL

  Chanan Khan, A. A. & Chini, E. N.

  National Cancer Institute

  9/4/19 → 8/31/22

  Project: Research project

  • T-Lymphocytes 100%
  • B-Lymphocytes 93%
  • daratumumab 68%
  • Neoplasms 65%
  • Study Guides 57%

• 2/4: Leveraging EHR-linked biobanks for deep phenotyping, polygenic risk score modeling, and outcomes analysis in psychiatric disorders

  Biernacka, J. M.

  National Institute of Mental Health, NATIONAL INSTITUTE OF MENTAL HEALTH

  9/5/19 → 5/31/22

  Project: Research project

  • Electronic Health Records 100%
  • Mental Disorders 73%
  • Major Depressive Disorder 43%
  • Psychiatry 39%
  • Substance-Related Disorders 27%

• Precision immunoprofiling to reveal diagnostic biomarkers of latent TB infection

  Bailey, R. & Escalante, P.

  National Institute of Allergy and Infectious Diseases

  9/5/19 → 8/31/22

  Project: Research project

  • Latent Tuberculosis 100%
  • Tuberculosis 50%
  • Biomarkers 35%
  • Tuberculin Test 15%
  • Skin Tests 12%

• Decreasing Delirium through music (DDM) in critically ill older adults

  Chlan, L., Khan, B. & Khan, B.

  National Institute on Aging

  9/15/19 → 5/31/22

  Project: Research project

  • Delirium 100%
  • Music 87%
  • Critical Illness 67%
  • Intensive Care Units 41%
  • Coma 22%

• ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

  Boeve, B. F., Boxer, A., Rosen, H., Kremers, W. K., Rademakers, R. V., Kantarci, K. M. & Seeley, W.

  National Institute on Aging

  9/15/19 → 6/30/22

  Project: Research project

  • Frontotemporal Lobar Degeneration 100%
  • Dementia 12%
  • Alzheimer Disease 10%
  • Frontotemporal Dementia 9%
  • Information Dissemination 8%

• Frontiers in Congenital Disorders of Glycosylation

  Morava-Kozicz, E., Lam, C., Freeze, H., Dasari, S. & Kozicz, L. T.

  9/15/19 → 7/31/22

  Project: Research project

  • Congenital Disorders of Glycosylation 100%
  • Natural History 28%
  • Glycosylation 16%
  • Biomarkers 10%
  • NGLY1 deficiency 8%

• Mechanotransduction in gastrointestinal physiology

  Beyder, A.

  National Institute of Diabetes and Digestive and Kidney Diseases

  9/17/19 → 6/30/22

  Project: Research project

  • Enteroendocrine Cells 100%
  • Epithelial Cells 50%
  • Gastrointestinal Diseases 28%
  • Cellular Mechanotransduction 8%
  • Population 8%

• Utility of memantine in preventing cognitive dysfunction in children receiving cranial radiotherapy

  Laack, N. N.

  National Cancer Institute

  9/18/19 → 12/31/22

  Project: Research project

  • Memantine 100%
  • Cognitive Dysfunction 51%
  • Radiotherapy 48%
  • Child 28%
  • Brain 26%

• Protease Activated Receptor Targets for Myelin Regeneration

  Scarisbrick, I. A.

  National Multiple Sclerosis Society

  10/1/19 → 9/30/22

  Project: Research project

  • Proteinase-Activated Receptors 100%
  • Myelin Sheath 69%
  • Regeneration 56%
  • Nervous System 54%

• Protease Activated Receptor Targets for Myelin Regeneration

  Scarisbrick, I. A.

  National Multiple Sclerosis Society

  10/1/19 → 9/30/22

  Project: Research project

  • Proteinase-Activated Receptors 100%
  • Myelin Sheath 69%
  • Regeneration 56%
  • Nervous System 54%

• Cytokine Modulation of Chimeric Antigen Receptor T Cells to Increase Their Safety and Efficacy

  Kay, N. E.

  Congressionally Directed Medical Research Programs

  1/1/20 → …

  Project: Research project

  • Chimeric Antigen Receptors 100%
  • T-Lymphocytes 47%
  • Cell- and Tissue-Based Therapy 35%
  • Cytokines 24%
  • Safety 23%

• ALSENLITE: An Open-Label Pilot Study Of Senolytics For Alzheimer Disease

  Kirkland, J. L.

  Alzheimer's Association

  1/1/20 → …

  Project: Research project

  • Alzheimer Disease 100%
  • Research Personnel 77%
  • Pharmaceutical Preparations 76%
  • Clinical Trials 59%
  • Brain 54%

• Identification of Novel Protein Biomarkers and Targets to Overcome PARP Inhibitor Resistance

  Weroha, S.

  Congressionally Directed Medical Research Programs

  1/1/20 → …

  Project: Research project

  • Poly(ADP-ribose) Polymerase Inhibitors 100%
  • Biomarkers 27%
  • Proteins 23%
  • Neoplasms 19%
  • Heterografts 13%

• Identifying and Targeting Epigenetic Vulnerabilities in the Histone H3 Lysine 36 Methylation Axis in Renal Cell Cancer

  Robertson, K. D.

  Congressionally Directed Medical Research Programs

  1/1/20 → …

  Project: Research project

  • Epigenome 100%
  • Renal Cell Carcinoma 85%
  • Lysine 56%
  • Epigenomics 54%
  • Histones 54%

• Biomarkers to Improve Targeting of Breast Cancer Prevention in Women with Atypical Hyperplasia

  Degnim, A. C. & Radisky, D. C.

  National Cancer Institute

  1/1/20 → 12/31/22

  Project: Research project

  • Hyperplasia 100%
  • Biomarkers 73%
  • Breast Neoplasms 72%
  • Tamoxifen 67%
  • Breast 46%

• Post-Traumatic Epilepsy: A Longitudinal, Population-Based Medical Record Review Analysis of Incidence, Risk, and Prediction

  Brown, A. W.

  Congressionally Directed Medical Research Programs

  1/1/20 → …

  Project: Research project

  • Traumatic Brain Injury 100%
  • Post-Traumatic Epilepsy 86%
  • Medical Records 53%
  • Population 27%
  • Incidence 26%

• Improved Training Method for Advanced Rehabilitation of Warfighters with Lower Extremity Trauma

  Kaufman, K. R.

  Congressionally Directed Medical Research Programs

  1/1/20 → …

  Project: Research project

  • Patient rehabilitation 100%
  • Lower Extremity 87%
  • Rehabilitation 82%
  • Accidental Falls 66%
  • Amputation 59%

• 3D Multimodal Ultrasound Imaging for Breast Cancer Screening in Women with Dense Breasts

  Chen, S. D.

  Congressionally Directed Medical Research Programs

  1/1/20 → …

  Project: Research project

  • Multimodal Imaging 100%
  • Breast 76%
  • Ultrasonography 65%
  • Early Detection of Cancer 55%
  • Breast Neoplasms 50%

• Targeting and eliminating senescent pre-tumor cells to prevent cancer

  Weivoda, M.

  American Federation for Aging Research

  1/1/20 → …

  Project: Research project

  • Neoplasms 100%
  • Plasmacytoma 49%
  • Phenotype 47%
  • Frailty 45%
  • Multiple Myeloma 38%

• Pharmacodynamic Biomarker-Guided Metabolic Collapse of IDH-Mutant Glioma

  Burns, T.

  Congressionally Directed Medical Research Programs

  1/1/20 → …

  Project: Research project

  • Nicotinamide Phosphoribosyltransferase 100%
  • Glioma 95%
  • NAD 59%
  • Biomarkers 46%
  • Neoplasms 41%

• Optimizing stroke prevention for older adults with atrial fibrillation: Towards rigorous evaluation and judicious application of a new device

  Noseworthy, P. & Yao, X.

  National Institute on Aging

  1/1/20 → 11/30/22

  Project: Research project

  • Atrial Fibrillation 100%
  • Stroke 87%
  • Equipment and Supplies 67%
  • Decision Support Techniques 66%
  • Patient-Centered Care 57%

• The role of nuclear PD-L1 in breast tumor cell division, progression and therapy response

  Lou, Z. & Wang, L. M.

  National Cancer Institute

  3/1/20 → 2/28/23

  Project: Research project

  • Cell Division 100%
  • Cell- and Tissue-Based Therapy 99%
  • Ligands 77%
  • Breast Neoplasms 71%
  • Triple Negative Breast Neoplasms 39%

• Quantitative magnetization transfer MRI for evaluation of renal fibrosis

  Lerman, L. O. & Lerman, L. O.

  National Institute of Diabetes and Digestive and Kidney Diseases

  3/15/20 → 1/31/23

  Project: Research project

  • Fibrosis 100%
  • Kidney 77%
  • Magnetic Resonance Imaging 47%
  • Vascular Diseases 33%
  • Swine 26%

• Gastrointestinal Cues Influence Metabolic Control of Regulatory T cell Function

  Bamidele, A.

  National Institute of Diabetes and Digestive and Kidney Diseases

  4/1/20 → 12/31/22

  Project: Research project

  • Regulatory T-Lymphocytes 100%
  • Cues 87%
  • Inflammatory Bowel Diseases 79%
  • Mitochondria 33%
  • Animal Diseases 21%

• Structural biology of DNA damage response in chromatin

  Mer, G.

  National Institute of General Medical Sciences

  5/1/20 → 2/28/23

  Project: Research project

  • Chromatin 100%
  • DNA Damage 98%
  • Homologous Recombination 74%
  • Poly(ADP-ribose) Polymerase Inhibitors 62%
  • Ubiquitination 56%

• Comprehensive characterization of coronary atherosclerotic disease using photon-counting-detector dual-source CT and its impact on patient management

  Leng, S. & McCollough, C. H.

  National Institute of Biomedical Imaging and Bioengineering

  5/1/20 → 1/31/23

  Project: Research project

  • Photons 100%
  • Imaging techniques 70%
  • Detectors 66%
  • Dosimetry 37%
  • Coronary Disease 27%

• The Role of miR-219a-5p in Bone Metabolism

  Monroe, D. G. & Monroe, D. G.

  National Institute on Aging

  5/1/20 → 1/31/23

  Project: Research project

  • metabolism 100%
  • bones 94%
  • Bone and Bones 57%
  • Wnt Signaling Pathway 25%
  • osteogenesis 24%

• BAK Autoactivation in Hematological Malignancies

  Kaufmann, S. H.

  National Cancer Institute

  7/1/20 → 6/30/22

  Project: Research project

  • Acute Myeloid Leukemia 100%
  • Hematologic Neoplasms 97%
  • pevonedistat 91%
  • Mitochondrial Membranes 87%
  • Leukemia 64%

• Structure-Resolved Mechanistic Phenotyping of Von Willebrand Disease

  Auton, M. T.

  National Heart, Lung, and Blood Institute

  7/1/20 → 6/30/22

  Project: Research project

  • von Willebrand Diseases 100%
  • von Willebrand Factor 79%
  • Blood Platelets 37%
  • Mutation 18%
  • Binding Sites 12%

• Mayo Clinic StARR Program

  Garovic, V. D. & Nath, K. A.

  National Heart, Lung, and Blood Institute

  7/1/20 → 6/30/22

  Project: Research project

  • Internship and Residency 100%
  • Sleep Wake Disorders 49%
  • Research Personnel 45%
  • Lung 24%
  • Mentors 24%

• The effect of endogenous GLP-1 secretion on islet function in vivo

  Vella, A.

  National Institute of Diabetes and Digestive and Kidney Diseases

  7/1/20 → 6/30/22

  Project: Research project

  • Glucagon-Like Peptide 1 100%
  • Fasting 27%
  • Glucagon-Like Peptide-1 Receptor 26%
  • Glucagon 21%
  • Glucose 17%

• Basic Technology Research and Feasibility Demonstration of Tactical Secure Long-Range RF Communications and Geolocation for Remote Autonomous Health Status

  Haider, C. R.

  U.S. Navy, Office of Naval Research

  7/1/20 → 6/30/23

  Project: Research project

  • Integrated circuits 100%
  • Health 86%
  • Demonstrations 72%
  • Communication 54%
  • Feedback 45%

• Targeting CEBPA To Restore Epithelial-Mesenchymal Homeostasis In Lung Fibrosis

  Tan, Q.

  National Heart, Lung, and Blood Institute

  7/15/20 → 6/30/22

  Project: Research project

  • Fibrosis 100%
  • Homeostasis 85%
  • Lung 78%
  • Pulmonary Fibrosis 58%
  • Epithelial Cells 54%

• Development of Novel Intra-aneurysmal Rapid Occlusion Device

  Hebert, S. & Kallmes, D. F.

  National Institute of Neurological Disorders and Stroke

  8/1/20 → 7/31/22

  Project: Research project

  • coils 100%
  • healing 93%
  • occlusion 92%
  • rabbits 46%
  • platinum 39%

• Interdisciplinary Infrastructure for Aging Research: Rochester Epidemiology Project

  LeBrasseur, N. K., Olson, J. E. & St Sauver, J. L.

  National Institute on Aging

  8/1/20 → 5/31/22

  Project: Research project

  • Electronic Health Records 100%
  • Epidemiology 61%
  • National Institute on Aging (U.S.) 52%
  • Geriatrics 46%
  • Biomarkers 31%

• Assessment of Alcoholic Hepatitis with Multiparametric Magnetic Resonance Elastography

  Shah, V. & Yin, M.

  National Institute on Alcohol Abuse and Alcoholism

  8/15/20 → 6/30/22

  Project: Research project

  • Alcoholic Hepatitis 100%
  • Elasticity Imaging Techniques 81%
  • interleukin-22 29%
  • AA005 25%
  • Biomarkers 14%

• Diagnosis of indeterminate brain lesions using MRI-based machine learning and polygenic risk models

  Eckel-Passow, J. E. & Tobin, O.

  National Institute of Neurological Disorders and Stroke

  8/15/20 → 5/31/22

  Project: Research project

  • Glioma 100%
  • Machine Learning 83%
  • Demyelinating Diseases 48%
  • Brain 45%
  • Central Nervous System 34%

• Skeletal muscle performance and cellular adaptations to high hemoglobin-oxygen affinity

  Senefeld, J.

  National Heart, Lung, and Blood Institute

  8/26/20 → 5/25/22

  Project: Research project

  • Skeletal Muscle 100%
  • Hemoglobins 94%
  • Oxygen 65%
  • Mentors 50%
  • Skeletal Muscle Fibers 45%

• Working towards targeted therapy in H3K27M tumors: Aurora Kinase Inhibitors and the role of epigenome programming

  Daniels, D.

  National Institute of Neurological Disorders and Stroke

  9/1/20 → 5/31/22

  Project: Research project

  • Aurora Kinases 100%
  • Epigenome 67%
  • Mutation 41%
  • Diffuse Intrinsic Pontine Glioma 30%
  • Mitosis 27%

• Intercellular transfer of cytoplasm and measles virus through nectins

  Cattaneo, R.

  National Institute of Allergy and Infectious Diseases

  9/1/20 → 8/31/22

  Project: Research project

  • Nectins 100%
  • Measles virus 81%
  • Cytoplasm 41%
  • Neurons 25%
  • Subacute Sclerosing Panencephalitis 19%

• Density MATTERS Clinical Trial

  Hruska, C. B. & Rhodes, D.

  National Cancer Institute

  9/1/20 → 5/31/22

  Project: Research project

  • Mammography 100%
  • Breast 93%
  • Molecular Imaging 76%
  • Clinical Trials 56%
  • Breast Neoplasms 27%

• FW-HTF-RM: Introducing Patient-Specific Therapy Profiles in Electronic Health Records for Guiding Treatment Selection in the Era of Genomic Medicine

  Athreya, A., Wang, L. M., Bobo, W. V., Dyrbye, L. & Sharp, R. R.

  National Science Foundation

  9/1/20 → 8/31/23

  Project: Research project

  • Electronic Health Records 100%
  • Medicine 44%
  • Machine Learning 28%
  • Technology 27%
  • Psychological Burnout 19%

• Single non-integrating RNA vector for gene editing and reprogramming of Fanconi anemia fibroblasts

  Devaux, P.

  National Heart, Lung, and Blood Institute

  9/1/20 → 8/31/22

  Project: Research project

  • Induced Pluripotent Stem Cells 100%
  • Fanconi Anemia 94%
  • Gene Editing 75%
  • Fibroblasts 56%
  • Measles virus 45%