Rochester, MN

Projects

Projects per year 1984 2003 2004 2009 2012 2013 2014 2015 2016 2017 2018 2019 2021 2025

• 106 Active
• 352 Finished

Projects per year

Search results

• Exploiting a Metabolic Dependency of PARPinhibitor-Resistant Ovarian Cancer

  Kanakkanthara, A.

  Ovarian Cancer Research Alliance

  1/1/21 → 12/31/23

  Project: Research project

  • Poly(ADP-ribose) Polymerase Inhibitors 100%
  • Ovarian Neoplasms 60%
  • Nicotinamide-Nucleotide Adenylyltransferase 51%
  • Homologous Recombination 21%
  • Platinum 9%

• Clinical Core

  Knopman, D. S. & Knopman, D. S.

  5/1/19 → 4/30/24

  Project: Research project

  • Frontotemporal Lobar Degeneration 100%
  • Organized Financing 83%
  • African Americans 66%
  • Alzheimer Disease 55%
  • Multimodal Imaging 47%

• Research Education Component

  Boeve, B. F. & Boeve, B. B. F.

  5/1/19 → 4/30/24

  Project: Research project

  • dementia 100%
  • trainee 18%
  • education 16%
  • leader 12%
  • director 11%

• Administrative Core

  Petersen, R. C. & Petersen, R. R. C.

  5/1/19 → 4/30/24

  Project: Research project

  • Alzheimer Disease 100%
  • National Institute on Aging (U.S.) 29%
  • Data Management 24%
  • Financial Support 24%
  • Geographic Locations 23%

• Neuroimaging Core

  Kantarci, K. M. & Kantarci, K. K.

  5/1/19 → 4/30/24

  Project: Research project

  • Neuroimaging 100%
  • Biomarkers 39%
  • African Americans 34%
  • Dementia 20%
  • Data Management 16%

• Data Management and Statistical Core

  Kremers, W. K. & Kremers, W. K.

  5/1/19 → 4/30/24

  Project: Research project

  • Information management 100%
  • Neurodegenerative diseases 54%
  • Statistical methods 45%
  • Biomarkers 22%
  • Data Sharing 20%

• Assessment of Beta Cell Small Extracellular Vesicles in the Pathogenesis of Type 1 Diabetes

  Javeed, N.

  Juvenile Diabetes Research Foundation United States of America

  9/1/22 → 8/31/24

  Project: Research project

  • Extracellular Vesicles 100%
  • Type 1 Diabetes Mellitus 90%
  • Biomarkers 23%
  • Type 2 Diabetes Mellitus 13%
  • Health 8%

• CAREER: Engineering genome topology to attenuate pathologic short tandem repeat instability

  Petersen, R. C.

  National Science Foundation

  7/1/20 → 6/30/25

  Project: Research project

  • Microsatellite Repeats 100%
  • Genome 42%
  • Fragile X Syndrome 29%
  • Human Genome 23%
  • Nervous System Diseases 21%

• Collaborative Research: SCH: A Causal AI Digital Twin Framework to Transform Intensive Care Delivery

  Schulte, P., Gajic, O. O. & Dong, Y. Y.

  National Science Foundation

  9/1/21 → 8/31/25

  Project: Research project

  • Digital twin 100%
  • Intensive care units 61%
  • Health 50%
  • Medicine 46%
  • Mathematical transformations 42%

• A Phase I Clinical Trial in Osteoarthritis Gene Therapy

  Evans, C. H.

  Congressionally Directed Medical Research Programs

  1/1/15 → …

  Project: Research project

  • Osteoarthritis 79%
  • Joints 73%
  • Genetic Therapy 69%
  • Clinical Trials, Phase I 68%
  • Genes 26%

• Targeting Fatty Acid Synthase: A mechanism-guided approach to develop a novel therapeutic intervention for drug-resistant breast cancer

  Haddad, T. C.

  Congressionally Directed Medical Research Programs

  1/1/15 → …

  Project: Research project

  • Fatty Acid Synthases 100%
  • Breast Neoplasms 50%
  • Trastuzumab 48%
  • Neoplasms 26%
  • taxane 26%

• Understanding the Connection Between Traumatic Brain Injury and Alzheimer's Disease: A Population-Based Medical Record Review Analysis

  Brown, A. W.

  Congressionally Directed Medical Research Programs

  1/1/14 → …

  Project: Research project

  • brain 100%
  • Medical records 96%
  • dementia 89%
  • Group 13%
  • Clinical experience 8%

• Early Detection, Accurate Staging, and Biologic Characterization of HCC with Hybrid 68Ga-PSMA-Dual-Contrast PET/MRI Using Cyclotron-Produced 68Ga

  Goenka, A.

  Congressionally Directed Medical Research Programs

  1/1/19 → …

  Project: Research project

  • Hepatocellular Carcinoma 100%
  • Cyclotrons 97%
  • Prostate-Specific Antigen 75%
  • Electrons 54%
  • Tomography 46%

• Myoelectrically Controlled Power-Assist Upper Extremity Exoskeleton

  Kaufman, K. R.

  Congressionally Directed Medical Research Programs

  1/1/19 → …

  Project: Research project

  • Upper Extremity 100%
  • Psychological Power 72%
  • Orthotic Devices 51%
  • Arm 42%
  • Extremities 36%

• Genetic Modifiers of Ovarian Cancer

  Couch, F. J.

  Congressionally Directed Medical Research Programs

  1/1/09 → …

  Project: Research project

  • Ovarian Neoplasms 100%
  • Mutation 40%
  • Genome-Wide Association Study 20%
  • Breast Neoplasms 17%
  • Ovariectomy 8%

• Metabolic alterations driving PDAC-associated muscle wasting

  Doles, J.

  American Association for Cancer Research

  1/1/17 → …

  Project: Research project

  • Pancreatic Neoplasms 100%
  • Cachexia 97%
  • Muscles 70%
  • Muscle Cells 48%
  • Regeneration 44%

• Can subtle cognitive decline predict biomarker positivity and incident MCI

  Stricker, N.

  Alzheimer’s Association

  1/1/17 → …

  Project: Research project

  • Cognitive Dysfunction 100%
  • Verbal Learning 55%
  • Biomarkers 50%
  • Brain 40%
  • Amyloid 39%

• Understanding the Cooperation Between LMO1 and MYCN in Neuroblastoma Metastasis Using a Novel Zebrafish Model

  Zhu, J.

  Congressionally Directed Medical Research Programs

  1/1/16 → …

  Project: Research project

  • Neuroblastoma 100%
  • Zebrafish 61%
  • Neoplasm Metastasis 57%
  • Oncogenes 15%
  • Neoplasms 13%

• The Role of PTPRD as a Tumor Suppressor in Neuroblastoma Pathogenesis

  Zhu, J.

  Alex's Lemonade Stand Foundation for Childhood Cancer

  1/1/13 → …

  Project: Research project

  • Neuroblastoma 100%
  • Interrenal Gland 44%
  • Neoplasms 29%
  • Sympathetic Ganglia 29%
  • Sympathetic Nervous System 25%

• Targeting and eliminating senescent pre-tumor cells to prevent cancer

  Weivoda, M.

  American Federation for Aging Research

  1/1/20 → …

  Project: Research project

  • Neoplasms 100%
  • Plasmacytoma 49%
  • Phenotype 47%
  • Frailty 45%
  • Multiple Myeloma 38%

• Improved Healing of Large, Osseous, Segmental Defects by Reverse Dynamization: Evaluation in a Sheep Model

  Evans, C. H.

  Congressionally Directed Medical Research Programs

  1/1/12 → …

  Project: Research project

  • bones 100%
  • sheep 52%
  • surgery 16%
  • rats 13%
  • patient care 12%

• Targeting Selective Gut Microbiome and Their Metabolites for Therapeutic and Pathogenic Potential in Rheumatoid Arthritis

  Taneja, V. D.

  Congressionally Directed Medical Research Programs

  1/1/14 → …

  Project: Research project

  • rheumatoid arthritis 100%
  • digestive system 55%
  • microbiome 41%
  • bacteria 38%
  • therapeutics 35%

• Mayo Clinic Traumatic Brain Injury Model System

  Brown, A. W.

  National Institute on Disability, Independent Living, and Rehabilitation Research

  1/1/17 → …

  Project: Research project

  • Traumatic Brain Injury 100%
  • Health Services Needs and Demand 23%
  • Telemedicine 23%
  • Costs and Cost Analysis 13%
  • Rehabilitation Centers 13%

• Cortical Lesions as Determinants of White Matter Lesion Formation and Cognitive Abnormalities in MS

  Port, J. D.

  Congressionally Directed Medical Research Programs

  1/1/12 → …

  Project: Research project

  • Multiple Sclerosis 100%
  • White Matter 95%
  • Gray Matter 64%
  • Magnetic Resonance Imaging 30%
  • Brain 22%

• The Role of EZH2 in PTEN-Deficient Prostate Cancer Pathogenesis and Therapy

  Huang, H.

  Congressionally Directed Medical Research Programs

  1/1/13 → …

  Project: Research project

  • Prostatic Neoplasms 100%
  • Docetaxel 21%
  • Neoplasms 20%
  • Hormones 18%
  • Therapeutics 18%

• Identification of Novel Targetable NPC-Mitotic Regulated Mechanisms in Lethal Prostate Cancer

  Rodriguez Bravo, V.

  Prostate Cancer Foundation

  1/1/18 → …

  Project: Research project

  • Nuclear Pore Complex Proteins 100%
  • Nuclear Pore 92%
  • Prostatic Neoplasms 75%
  • tetrachloroisophthalonitrile 37%
  • Cell Division 32%

• Promoting an Effective Antitumor Immune Response in Lymphoma

  Ansell, S. M.

  Congressionally Directed Medical Research Programs

  1/1/17 → …

  Project: Research project

  • T-Lymphocytes 100%
  • Lymphoma 98%
  • T-Cell Lymphoma 43%
  • Lymphoma, Large B-Cell, Diffuse 42%
  • Neoplasms 36%

• Phase I Trial of Intratumoral Administration of NIS-Expressing Strain of Measles Virus in Unresectable or Recurrent Malignant Peripheral Nerve Sheath Tumor

  Babovic-Vuksanovic, D.

  Congressionally Directed Medical Research Programs

  1/1/14 → …

  Project: Research project

  • Neurofibrosarcoma 100%
  • Measles virus 80%
  • Neurofibromatosis 1 70%
  • Neoplasms 24%
  • Viruses 19%

• Complement regulation and anti-CD20 efficacy in follicular lymphoma

  Rogers, L.

  American Association for Cancer Research

  1/1/14 → …

  Project: Research project

• Reversing Pulmonary Fibrosis Through Dopamine D1 Receptor Agonism

  Tschumperlin, D. J.

  Congressionally Directed Medical Research Programs

  1/1/18 → …

  Project: Research project

  • Dopamine D1 Receptors 100%
  • Pulmonary Fibrosis 81%
  • Idiopathic Pulmonary Fibrosis 76%
  • Lung 55%
  • Fibroblasts 46%

• Development of a Personal Use Seating Pressure Measurement System

  Morrow, M. M.

  Congressionally Directed Medical Research Programs

  1/1/14 → …

  Project: Research project

  • Pressure 100%
  • Spinal Cord Injuries 88%
  • Pressure Ulcer 83%
  • Sitting Position 34%
  • Veterans 34%

• New Pilot Projects

  Scarisbrick, I. A.

  National Multiple Sclerosis Society

  6/1/13 → …

  Project: Research project

  • pilot project 100%
  • repair 82%

• The FA-BRCA Pathway and Response to Platinum and PARP Inhibitors in Ovarian, Tubal and Peritoneal Carcinomas

  Haluska, P. R. J., Kaufmann, S. H. & Swisher, E. E.

  Ovarian Cancer Research Fund

  1/1/13 → …

  Project: Research project

  • Poly(ADP-ribose) Polymerase Inhibitors 100%
  • Platinum 73%
  • Carcinoma 46%
  • Ovarian Neoplasms 42%
  • Biomarkers 30%

• Personalized Medicine for Patients with BRAF wild-type (BRAFwt) Cancer

  Trent, J. M. J. M., Lorusso, P. P., Schork, N. J. N. J., Nickoloff, B. B., Webb, C. P. C. P., Sekulic, A. A., Markovic, S. N. & Vuori, K. K.

  Melanoma Research Alliance

  1/1/12 → …

  Project: Research project

  • Precision Medicine 100%
  • Melanoma 46%
  • Neoplasms 34%
  • Dreams 33%
  • Therapeutics 22%

• High Spatiotemporal Resolution Prostate MRI

  Riederer, S. J.

  Congressionally Directed Medical Research Programs

  1/1/14 → …

  Project: Research project

  • Magnetic resonance 100%
  • Imaging techniques 81%
  • Men's Health 23%
  • Blood 20%
  • Antigens 15%

• Identifying and Targeting Epigenetic Vulnerabilities in the Histone H3 Lysine 36 Methylation Axis in Renal Cell Cancer

  Robertson, K. D.

  Congressionally Directed Medical Research Programs

  1/1/20 → …

  Project: Research project

  • Epigenome 100%
  • Renal Cell Carcinoma 85%
  • Lysine 56%
  • Epigenomics 54%
  • Histones 54%

• Advancing Rehabilitation: Physiological, Psychological, and Neuroimaging Measures of Factors That Predispose, Promote, and Perpetuate Posttraumatic Dizziness

  Staab, J. P.

  Congressionally Directed Medical Research Programs

  1/1/17 → …

  Project: Research project

  • Dizziness 100%
  • Neuroimaging 53%
  • Rehabilitation 38%
  • Psychology 38%
  • Triage 32%

• Studies of mRNA Translational Regulations in Diamond Blackfan Anemia

  Hu, W.

  Congressionally Directed Medical Research Programs

  1/1/17 → …

  Project: Research project

  • Diamond-Blackfan Anemia 100%
  • Formal Social Control 76%
  • Erythrocytes 54%
  • Bone Marrow Failure Disorders 37%
  • Messenger RNA 25%

• 2018 FRIENDS OF THE AACR FOUNDATION EARLY CAREER INVESTIGATOR AWARD

  Rodriguez Bravo, V.

  American Association for Cancer Research

  1/1/18 → …

  Project: Research project

  • Prostatic Neoplasms 100%
  • Nuclear Pore Complex Proteins 93%
  • Genome 64%
  • Research Personnel 54%
  • tetrachloroisophthalonitrile 52%

• Phase 1 Clinical Trial of a Novel HER2 Vaccine for Patients with DCIS

  Degnim, A. C.

  Congressionally Directed Medical Research Programs

  1/1/15 → …

  Project: Research project

  • Carcinoma, Intraductal, Noninfiltrating 100%
  • Vaccines 63%
  • Clinical Trials, Phase I 60%
  • Breast Neoplasms 27%
  • Immunization 18%

• Targeting Fatty Acid Synthase: A mechanism-guided approach to develop a novel therapeutic intervention for drug-resistant breast cancer

  Lupu, R.

  Congressionally Directed Medical Research Programs

  1/1/15 → …

  Project: Research project

  • Fatty Acid Synthases 100%
  • Breast Neoplasms 50%
  • Trastuzumab 48%
  • Neoplasms 26%
  • taxane 26%

• Commensal Gut-Derived Anaerobes as Novel Therapy for Inflammatory Autoimmune Diseases

  Taneja, V. D.

  Congressionally Directed Medical Research Programs

  1/1/09 → …

  Project: Research project

  • Autoimmune Diseases 100%
  • Multiple Sclerosis 85%
  • Rheumatoid Arthritis 79%
  • Bacteria 78%
  • Histocompatibility Antigens Class II 42%

• Oncolytic Single-Cycle Replicating Immunotherapies for Kidney Cancer

  Barry, M. A.

  Congressionally Directed Medical Research Programs

  1/1/18 → …

  Project: Research project

  • kidney neoplasms 100%
  • immunotherapy 48%
  • therapeutics 45%
  • immune system 41%
  • neoplasm cells 39%

• Feedforward Signaling Between Glia, Neurons, and Mast Cells Contributes to Polyp Formation and Growth

  Linden, D. R.

  Congressionally Directed Medical Research Programs

  1/1/17 → …

  Project: Research project

  • Colorectal Neoplasms 100%
  • Polyps 80%
  • Neuroglia 78%
  • Mast Cells 76%
  • Neurons 64%

• Omega-3 Fatty Acids: Opportunities as Aging Countermeasures

  Lanza, I. R.

  American Federation for Aging Research

  1/1/11 → …

  Project: Research project

  • Fish Oils 100%
  • Omega-3 Fatty Acids 59%
  • Mitochondria 44%
  • Insulin 36%
  • Complementary Therapies 27%

• Development of Assays for Detecting Significant Prostate Cancer Based on Molecular Alterations Associated with Cancer in Non-Neoplastic Prostate Tissue

  Kosari, F.

  Congressionally Directed Medical Research Programs

  1/1/10 → …

  Project: Research project

  • Prostate 100%
  • Prostatic Neoplasms 89%
  • Neoplasm Grading 77%
  • Biopsy 67%
  • Neoplasms 61%

• Evaluation of the Cardiac and Metabolic Effects of Semaglutide in Heart Failure with Preserved Ejection Fraction

  Borlaug, B. A.

  Congressionally Directed Medical Research Programs

  1/1/21 → …

  Project: Research project

  • semaglutide 100%
  • Cardiomyopathies 70%
  • Heart 51%
  • Obesity 50%
  • Heart Failure 46%

• Improved Training Method for Advanced Rehabilitation of Warfighters with Lower Extremity Trauma

  Kaufman, K. R.

  Congressionally Directed Medical Research Programs

  1/1/20 → …

  Project: Research project

  • Patient rehabilitation 100%
  • Lower Extremity 87%
  • Rehabilitation 82%
  • Accidental Falls 66%
  • Amputation 59%

• The GNAS1 Gene as a Regulator of Osteoblast Differentiation and Molecular Target for the Stimulation of Bone Formation

  Pignolo, R.

  American Federation for Aging Research

  1/1/02 → …

  Project: Research project

• Targeted Inhibition of DNA Repair Protein TIRR with Aptamers to Counteract Resistance of Ovarian Cancer Cells to PARP Inhibitors

  Mer, G.

  Congressionally Directed Medical Research Programs

  1/1/19 → …

  Project: Research project

  • Resistance 100%
  • Molecule 80%
  • Protein 65%
  • Drug 61%
  • Surface 27%