Rochester, MN

Projects

Projects per year 1989 2002 2009 2014 2015 2016 2017 2018 2019 2021 2025

• 9 Not started
• 357 Active
• 873 Finished

Projects per year

Search results

• Impact of Clot Histological and Physical Properties on Revascularization Strategies in Acute Ischaemic Stroke - Administrative Supplement

  Brinjikji, W.

  National Institute of Neurological Disorders and Stroke

  4/15/18 → 1/31/22

  Project: Research project

  • Stroke 100%
  • Thrombectomy 28%
  • Embolism 28%
  • Deep Learning 24%
  • Registries 22%

• Overcoming immune checkpoint inhibition with therapeutic plasma exchange and radiotherapy in melanoma

  Orme, J. & Park, S. S.

  National Cancer Institute

  2/5/21 → 1/31/22

  Project: Research project

  • Plasma Exchange 100%
  • Melanoma 89%
  • Radiosurgery 59%
  • Radiotherapy 56%
  • Psychological Inhibition 51%

• Mechanism and role of aberrant AR activity in castration-resistant prostate cancer

  Huang, H.

  National Cancer Institute

  2/5/18 → 1/31/22

  Project: Research project

  • Androgen Receptors 100%
  • Castration 99%
  • Prostatic Neoplasms 78%
  • MDV 3100 61%
  • abiraterone 18%

• Comprehensive characterization of coronary atherosclerotic disease using photon-counting-detector dual-source CT and its impact on patient management

  Leng, S. & McCollough, C. H.

  National Institute of Biomedical Imaging and Bioengineering

  2/1/21 → 1/31/22

  Project: Research project

  • Photons 100%
  • Imaging techniques 72%
  • Detectors 66%
  • Dosimetry 39%
  • Noise abatement 21%

• Genetic analysis of the ciliopathies ARPKD and Meckel syndrome

  Harris, P. C.

  National Institute of Diabetes and Digestive and Kidney Diseases

  4/15/02 → 1/31/22

  Project: Research project

  • polycystins 100%
  • genetically modified organisms 43%
  • Autosomal Recessive Polycystic Kidney 33%
  • mice 23%
  • Phenotype 19%

• Congenital Myasthenic Syndromes

  Engel, A. G., Selcen, D. & Shen, X. M.

  National Institute of Neurological Disorders and Stroke

  2/15/19 → 1/31/22

  Project: Research project

  • Congenital Myasthenic Syndromes 100%
  • Genes 24%
  • Phenotype 21%
  • Whole Exome Sequencing 14%
  • Safety 13%

• Targeting cellular senescence with senolytics to improve skeletal health in older humans

  Farr, J. & Khosla, S.

  National Institute on Aging

  2/1/21 → 1/31/22

  Project: Research project

  • Osteoporosis 53%
  • Health 38%
  • Chronic Disease 26%
  • Placebos 25%
  • Nexus 17%

• Role of senescent cells in the pathogenesis of Marfan-associated cardiovascular disease

  Miller, J. D.

  National Heart, Lung, and Blood Institute

  3/1/18 → 1/31/22

  Project: Research project

  • Marfan Syndrome 100%
  • Cardiovascular Diseases 49%
  • Mitral Valve 33%
  • Aortic Valve 32%
  • Phenotype 26%

• Systemic Cell Senescence as a Mediator of Brain Aging Through Circulation

  Marissa, S.

  National Institute on Aging

  5/1/21 → 1/31/22

  Project: Research project

  • Proteome 44%
  • Brain 44%
  • Blood Circulation 37%
  • Cognitive Dysfunction 26%
  • Dementia 17%

• Molecular Mechanisms of Cholestatic Fibrogenesis

  Huebert, R. C.

  National Institute of Diabetes and Digestive and Kidney Diseases

  2/15/19 → 1/31/22

  Project: Research project

  • Enhancer of Zeste Homolog 2 Protein 100%
  • Hepatic Stellate Cells 69%
  • Fibronectins 47%
  • Acetylation 42%
  • Fibrosis 42%

• Home Based Rehabilitation for COPD

  Benzo, R. P.

  National Heart, Lung, and Blood Institute

  3/5/18 → 1/31/22

  Project: Research project

  • Chronic Obstructive Pulmonary Disease 100%
  • Rehabilitation 97%
  • Lung 66%
  • Self-Management 53%
  • Professional Practice Gaps 18%

• Adipose-derived biogenic nanoparticles for treatment of myocarditis/DCM(MPDPI)

  Fairweather, D. & Wolfram, J.

  National Institute of Allergy and Infectious Diseases

  2/1/21 → 1/31/22

  Project: Research project

  • Myocarditis 100%
  • Dilated Cardiomyopathy 78%
  • Nanoparticles 66%
  • Toll-Like Receptor 4 41%
  • Anti-Inflammatory Agents 20%

• Identification and characterization of children with asthma-associated comorbidities through computational and immune phenotyping

  Juhn, Y. J. & Liu, H. D.

  National Heart, Lung, and Blood Institute

  4/1/15 → 1/31/22

  Project: Research project

  • Asthma 100%
  • Natural Language Processing 96%
  • Electronic Health Records 73%
  • Communicable Diseases 58%
  • Comorbidity 53%

• Targeting Cellular Senescence to Extend Healthspan

  Khosla, S., Kirkland, J. L., Robbins, P., Pignolo, R. J., Ikeno, Y. & LeBrasseur, N. K.

  National Institute on Aging

  6/1/19 → 1/31/22

  Project: Research project

  • Skeletal Muscle 39%
  • Muscles 19%
  • Biostatistics 16%
  • Pharmacology 16%
  • Drug Discovery 15%

• Neonatal immune response to gut originating pathogens

  Knoop, K.

  National Institute of Allergy and Infectious Diseases

  2/1/21 → 1/31/22

  Project: Research project

  • sepsis (infection) 100%
  • immune response 35%
  • pathogens 32%
  • digestive system 31%
  • neonates 18%

• Inflammatory cascades disrupt Treg function through epigenetic mechanisms

  Faubion, W. A.

  National Institute of Allergy and Infectious Diseases

  2/15/11 → 1/31/22

  Project: Research project

  • Regulatory T-Lymphocytes 100%
  • Epigenomics 58%
  • Colitis 55%
  • T-Lymphocytes 39%
  • Inflammation 32%

• Understanding measles vaccine failure (and success) in Southern India

  Jacob, J. & Kennedy, R. B.

  National Institute of Allergy and Infectious Diseases

  3/1/17 → 2/28/22

  Project: Research project

  • Measles Vaccine 100%
  • Measles 88%
  • India 58%
  • Vaccines 34%
  • Disease Outbreaks 34%

• Alliance Statistics and Data Management Center

  Mandrekar, S. J. & Sargent, D. J.

  National Cancer Institute

  4/17/14 → 2/28/22

  Project: Research project

  • Data Management 100%
  • Statistics 73%
  • Clinical Trials 37%
  • Manuscripts 19%
  • Adaptive Clinical Trials 19%

• Role of pH-mediated metabolic reprogramming in ? cell failure in Type 2 Diabetes Mellitus

  Matveyenko, A. V. & Romero, M. F.

  National Institute of Diabetes and Digestive and Kidney Diseases

  4/1/21 → 2/28/22

  Project: Research project

  • Type 2 Diabetes Mellitus 100%
  • Glucose 18%
  • Sodium-Bicarbonate Symporters 17%
  • Ion Pumps 15%
  • Bicarbonates 10%

• NCI, National Clinical Trials Network Lead Academic Participating Site (LAPS) UG1

  Alberts, S. R. & Boughey, J. C.

  National Cancer Institute

  4/12/19 → 2/28/22

  Project: Research project

  • Clinical Trials 100%
  • Research Personnel 22%
  • Organizations 19%
  • Neoplasms 10%
  • Physicians 10%

• Factors Influencing Access and Utilization of Genetic Prenatal Care Services Among Women from Underserved Populations

  Allyse, M.

  National Human Genome Research Institute

  3/5/18 → 2/28/22

  Project: Research project

  • utilization 100%
  • genetic services 48%
  • health 41%
  • national minority 26%
  • diagnostic services 24%

• Assessment of Metabolites Among Asymptomatic Precursor and Malignant Monoclonal Gammopathies

  Gonsalves, W.

  National Cancer Institute

  3/1/21 → 2/28/22

  Project: Research project

  • Multiple Myeloma 100%
  • Paraproteinemias 72%
  • Monoclonal Gammopathy of Undetermined Significance 61%
  • Plasma Cells 57%
  • Metabolomics 31%

• Designing Effective Health Education for Patients Seeking Unregulated Stem Cell Interventions

  Master, Z.

  National Institute on Aging

  5/1/21 → 2/28/22

  Project: Research project

  • health promotion 100%
  • credibility 40%
  • health behavior 30%
  • health information 30%
  • health 27%

• Regulation of B cell development by ABCB7

  Shapiro, V. M.

  National Institute of Allergy and Infectious Diseases

  3/17/21 → 2/28/22

  Project: Research project

  • Iron 100%
  • B-Lymphocytes 80%
  • Knockout Mice 55%
  • B-Lymphoid Precursor Cells 54%
  • Homeostasis 44%

• TrAstuzumab Cardiomyopathy Therapeutic Intervention with Carvedilol (TACTIC) Trial

  Herrmann, J. & Ruddy, K. J.

  National Cancer Institute

  3/1/19 → 2/28/22

  Project: Research project

  • Carvedilol 100%
  • Trastuzumab 93%
  • Cardiomyopathies 58%
  • Cardiotoxicity 47%
  • Stroke Volume 38%

• Interdisciplinary Training in Lung Physiology and Biomedical Engineering

  Prakash, Y. S., Sieck, G. C. & Sieck, G. C.

  National Heart, Lung, and Blood Institute

  3/1/12 → 2/28/22

  Project: Research project

  • engineering 100%
  • physiology 87%
  • lungs 81%
  • biomedical research 80%
  • students 54%

• Novel multipronged Immunovirotherapy Approach for GBM Treatment

  Galanis, E.

  National Cancer Institute

  3/1/21 → 2/28/22

  Project: Research project

  • Glioblastoma 100%
  • Neutrophils 49%
  • Interferons 43%
  • Measles virus 40%
  • Helicobacter pylori neutrophil-activating protein A 30%

• NorthStar Node of the Clinical Trials Network: Engaging African American Faith-Based Leaders in a Substance Use Learning Collaborative (LC)

  Bart, G., Patten, C. A. & Joseph, A.

  National Institute on Drug Abuse

  9/1/15 → 2/28/22

  Project: Research project

  • Interdisciplinary Placement 100%
  • Alaska Natives 93%
  • Opioid Analgesics 57%
  • Clinical Trials 50%
  • Recurrence 37%

• Mayo Comprehensive Cancer Center Grant

  Diasio, R. B., Fonseca, R., Salisbury, J. L., Pandey, A., Baker, D. J., Federspiel, M. J., Reid, J. M., Finnes, H., Cicek, M., Greipp, P. T., Wieben, E. D., Flotte, T. J., Kocher, J., Dueck, A., Yost, K. J., Anastasiadis, P. Z., Adjei, A., Borad, M. J., Knutson, K. L., Bekaii-Saab, T., Ansell, S. M., Sarkaria, J. N., Goetz, M. P., Loprinzi, C. L., Cerhan, J. R., Doubeni, C. A., Kumar, S. K., Dispenzieri, A., Prendergast, F. G., Kovach, J. S. & Moertel, C.

  National Cancer Institute

  12/31/89 → 2/28/22

  Project: Research project

  • Neoplasms 100%
  • Biostatistics 77%
  • neoplasms 65%
  • Genetic Therapy 62%
  • Research Personnel 46%

• Pathologic Role of Inflammation and Mechanistic Analysis of Myofibroblastogenesis in Arthrofibrosis

  Abdel, M.

  National Institute of Arthritis and Musculoskeletal and Skin Diseases

  4/1/18 → 2/28/22

  Project: Research project

  • Myofibroblasts 100%
  • Inflammation 57%
  • Joints 46%
  • Disease Progression 34%
  • Primary Cell Culture 26%

• Quantitative, non-invasive characterization of urinary stone composition and fragility using multi-energy CT and machine learning techniques

  McCollough, C. H.

  National Institute of Biomedical Imaging and Bioengineering

  6/1/19 → 2/28/22

  Project: Research project

  • Urinary Calculi 100%
  • Machine Learning 62%
  • Tomography 49%
  • Research Subjects 32%
  • Acids 16%

• Development of tools for site-directed analysis of gene function

  Clark, K. J., Ekker, S. C., Essner, J., Friedberg, I. & McGrail, M.

  NIH Office of the Director

  6/1/16 → 2/28/22

  Project: Research project

  • Danio rerio 100%
  • alleles 80%
  • gene editing 48%
  • methodology 47%
  • genes 47%

• Structural biology of DNA damage response in chromatin

  Mer, G.

  National Institute of General Medical Sciences

  3/1/21 → 2/28/22

  Project: Research project

  • Chromatin 100%
  • DNA Damage 98%
  • Post Translational Protein Processing 78%
  • Nucleosomes 59%
  • Homologous Recombination 57%

• The Role of Microglia in Epilepsy

  Wu, L.

  National Institute of Neurological Disorders and Stroke

  5/1/14 → 2/28/22

  Project: Research project

  • Microglia 100%
  • Epilepsy 78%
  • Seizures 61%
  • Glutamic Acid 50%
  • Chemotactic Factors 32%

• Small molecule mitochondria-targeted therapeutics for AD

  Trushina, E. D.

  National Institute of Neurological Disorders and Stroke

  3/1/21 → 2/28/22

  Project: Research project

  • Mitochondria 100%
  • Adenylate Kinase 73%
  • Systems Biology 64%
  • Neuroprotection 56%
  • Protein Kinases 49%

• Role of CD38 in NAD metabolism: from the basic biology of aging to translation

  Chini, E. N.

  National Institute on Aging

  6/1/18 → 2/28/22

  Project: Research project

  • NAD 100%
  • NAD+ Nucleosidase 22%
  • Longevity 11%
  • nicotinamide-beta-riboside 11%
  • Formoterol Fumarate 9%

• The role of nuclear PD-L1 in breast tumor cell division, progression and therapy response

  Lou, Z. & Wang, L. M.

  National Cancer Institute

  3/1/21 → 2/28/22

  Project: Research project

  • Ligands 100%
  • Triple Negative Breast Neoplasms 83%
  • Cell Division 70%
  • Cell- and Tissue-Based Therapy 70%
  • Breast Neoplasms 54%

• Regulation of Nutrient Homeostasis by COMMD proteins

  Billadeau, D. D. & Burstein, E.

  National Institute of Diabetes and Digestive and Kidney Diseases

  8/1/16 → 2/28/22

  Project: Research project

  • Proteostasis 100%
  • Copper 64%
  • Proteins 32%
  • Endosomes 28%
  • Homeostasis 25%

• The Mayo Clinic IMSD: Developing scientists through disease-relevant research

  Lujan, J. L., Maher, L. J., McGee, R., Maher, J. & Maher III, J.

  National Institute of General Medical Sciences

  9/30/96 → 2/28/22

  Project: Research project

  • Students 100%
  • student 64%
  • career 56%
  • minority 53%
  • Biomedical Research 28%

• Endocytic Trafficking of ADCs in GBM cancer stem-like cells

  Gladson, C. & Sarkaria, J. N.

  National Institute of Neurological Disorders and Stroke

  4/1/19 → 3/31/22

  Project: Research project

  • ABT-414 100%
  • Glioblastoma 64%
  • Neoplastic Stem Cells 63%
  • Immunoconjugates 26%
  • Recycling 16%

• Regional Fatty Acid Metabolism In Humans

  Jensen, M. D.

  National Institute of Diabetes and Digestive and Kidney Diseases

  9/30/92 → 3/31/22

  Project: Research project

  • Fatty Acids 100%
  • Fats 57%
  • Subcutaneous Fat 51%
  • Fatty Acid Transport Proteins 43%
  • Meals 38%

• The contribution of p16-expressing cells to tauopathy

  Baker, D. J.

  National Institute on Aging

  7/15/17 → 3/31/22

  Project: Research project

  • Tauopathies 100%
  • Alzheimer Disease 16%
  • Pathology 10%
  • Synthetic Drugs 7%
  • Neurofibrillary Tangles 6%

• Immunology of xenogeneic extracellular matrix scaffolds for heart valve tissue engineering

  Griffiths, L.

  National Heart, Lung, and Blood Institute

  4/1/21 → 3/31/22

  Project: Research project

  • Pericardium 100%
  • Heart Valves 90%
  • Extracellular Matrix 87%
  • Cattle 71%
  • Allergy and Immunology 60%

• The impact of age-related changes in osteoclast function on the skeleton (R01)

  Weivoda, M.

  National Institute of Arthritis and Musculoskeletal and Skin Diseases

  6/15/21 → 3/31/22

  Project: Research project

  • Osteoclasts 100%
  • Skeleton 52%
  • Bone and Bones 14%
  • Osteoporosis 12%
  • Osteogenesis 12%

• Memory T Cell Development and Survival in T Cell Responses of Older Individuals

  Goronzy, J.

  National Institute of Allergy and Infectious Diseases

  4/1/17 → 3/31/22

  Project: Research project

  • T-Lymphocytes 95%
  • Vaccination 44%
  • T-Lymphoid Precursor Cells 26%
  • Apoptosis 22%
  • Chickenpox 22%

• Multiple Chronic Conditions and Aging

  Rocca, W. A. & St. Sauver, J.

  National Institute on Aging

  4/1/17 → 3/31/22

  Project: Research project

  • Multiple Chronic Conditions 100%
  • Cohort Studies 36%
  • Biomarkers 34%
  • Health 34%
  • National Institute on Aging (U.S.) 28%

• Impact of Airway Inflammation on Mitochondria

  Prakash, Y. S. & Sieck, G. C.

  National Heart, Lung, and Blood Institute

  4/15/21 → 3/31/22

  Project: Research project

  • Endoplasmic Reticulum Stress 100%
  • Reactive Oxygen Species 82%
  • Mitochondria 79%
  • Mitochondrial Size 55%
  • Inflammation 45%

• Radiomic phenotypes of breast parenchyma and association with breast cancer risk and detection

  Kerlikowske, K., Kontos, D. & Vachon, C. M.

  National Cancer Institute

  4/1/17 → 3/31/22

  Project: Research project

  • Breast 100%
  • Breast Neoplasms 95%
  • Breast Density 91%
  • Phenotype 86%
  • Mammography 56%

• Senescence and Growth Differentiation Factors as Modifiers of Aging

  LeBrasseur, N. K.

  National Institute on Aging

  8/15/18 → 3/31/22

  Project: Research project

  • Growth Differentiation Factors 100%
  • Plasminogen Activator Inhibitor 2 41%
  • activin A 37%
  • Body Composition 26%
  • Proteins 26%

• Optimizing Pancreatic Cancer Management with Next Generation Imaging and Liquid Biopsy

  Collisson, E., Goenka, A. & Wang, Z. J.

  National Cancer Institute

  4/1/21 → 3/31/22

  Project: Research project

  • Liquid Biopsy 100%
  • Adenocarcinoma 84%
  • Pancreatic Neoplasms 67%
  • Positron-Emission Tomography 44%
  • Deoxyglucose 41%