Radiation Oncology

Research Output

2018

Carbon Fiducial Image Guidance Increases the Accuracy of Lumpectomy Cavity Localization in Radiation Therapy for Breast Cancer

Zhang, Y., Mutter, R., Park, S. S., Hieken, T. J., Yan, E. S., Corbin, K. S., Brinkmann, D. H. & Pafundi, D. H., Jan 1 2018, (Accepted/In press) In : Practical Radiation Oncology.

Research output: Contribution to journalArticle

1 Scopus citations

Cardiac resynchronization therapy improves myocardial conduction

Yang, M., Li, X., Yang, D., Li, Y., Zhou, S., Liang, J., Wu, G., Del-Carpio Munoz, F., Chen, H. H., Friedman, P. A. & Cha, Y-M., Jan 1 2018, (Accepted/In press) In : PACE - Pacing and Clinical Electrophysiology.

Research output: Contribution to journalArticle

1 Scopus citations

Cholangiocarcinoma-evolving concepts and therapeutic strategies

Rizvi, S., Khan, S. A., Hallemeier, C., Kelley, R. K. & Gores, G. J., Feb 1 2018, In : Nature Reviews Clinical Oncology. 15, 2, p. 95-111 17 p.

Research output: Contribution to journalReview article

149 Scopus citations

Clinical implementation of robust optimization for craniospinal irradiation

Tasson, A., Laack, N. N. & Beltran, C., Jan 1 2018, In : Cancers. 10, 1, 7.

Research output: Contribution to journalComment/debate

2 Scopus citations

Combining Immune Checkpoint Inhibitors With Conventional Cancer Therapy

Yan, Y., Kumar, A. B., Finnes, H., Markovic, S. N., Park, S., Dronca, R. S. & Dong, H., Jan 1 2018, In : Frontiers in immunology. 9, 1 p.

Research output: Contribution to journalReview article

Open Access
36 Scopus citations

Combining precision radiotherapy with molecular targeting and immunomodulatory agents: a guideline by the American Society for Radiation Oncology

Bristow, R. G., Alexander, B., Baumann, M., Bratman, S. V., Brown, J. M., Camphausen, K., Choyke, P., Citrin, D., Contessa, J. N., Dicker, A., Kirsch, D. G., Krause, M., Le, Q. T., Milosevic, M., Morris, Z. S., Sarkaria, J. N., Sondel, P. M., Tran, P. T., Wilson, G. D., Willers, H. & 2 others, Wong, R. K. S. & Harari, P. M., May 1 2018, In : The Lancet Oncology. 19, 5, p. e240-e251

Research output: Contribution to journalReview article

28 Scopus citations

Comparing Intensity-Modulated Proton Therapy With Intensity-Modulated Photon Therapy for Oropharyngeal Cancer: The Journey From Clinical Trial Concept to Activation

Frank, S. J., Blanchard, P., Lee, J. J., Sturgis, E. M., Kies, M. S., Machtay, M., Vikram, B., Garden, A. S., Rosenthal, D. I., Gunn, G. B., Fuller, C. D., Hutcheson, K., Lai, S., Busse, P. M., Lee, N. Y., Lin, A. & Foote, R. L., Jan 1 2018, (Accepted/In press) In : Seminars in Radiation Oncology.

Research output: Contribution to journalArticle

4 Scopus citations

Complete response of pleural effusions caused by extramedullary hematopoiesis to low-dose, single fraction palliative radiation therapy: Case report and literature review

Gits, H. C., Lester, S. C., McGrath, L. A. & Martenson, J. A., Jul 1 2018, In : Advances in Radiation Oncology. 3, 3, p. 463-466 4 p.

Research output: Contribution to journalArticle

Constitutive Interferon Pathway Activation in Tumors as an Efficacy Determinant Following Oncolytic Virotherapy

Kurokawa, C., Iankov, I. D., Anderson, S. K., Aderca, I., Leontovich, A. A., Maurer, M. J., Oberg, A. L., Schroeder, M. A., Giannini, C., Greiner, S. M., Becker, M. A., Thompson, E. A., Haluska, P., Jentoft, M. E., Parney, I. F., Weroha, S. J., Jen, J., Sarkaria, J. N. & Galanis, E., Oct 1 2018, In : Journal of the National Cancer Institute. 110, 10, p. 1123-1132 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Contraction of T cell richness in lung cancer brain metastases

Mansfield, A., Ren, H., Sutor, S., Sarangi, V., Nair, A., Davila, J., Elsbernd, L. R., Udell, J. B., Dronca, R. S., Park, S. S., Markovic, S. N., Sun, Z. D., Halling, K. C., Nevala, W. K., Aubry, M. C., Dong, H. M. & Jen, J., Dec 1 2018, In : Scientific Reports. 8, 1, 2171.

Research output: Contribution to journalArticle

20 Scopus citations
5 Scopus citations

Cross-modality comparisons between radiofrequency ablation and stereotactic body radiotherapy for treatment of hepatocellular carcinoma: Limitations of the national cancer database

Olsen, J. R., Murphy, J. D., Hallemeier, C. L., Apisarnthanarax, S., Huguet, F. & Jabbour, S. K., Aug 20 2018, In : Journal of Clinical Oncology. 36, 24, p. 2564-2565 2 p.

Research output: Contribution to journalLetter

1 Scopus citations

CX3CR1 identifies PD-1 therapy-responsive CD8+ T cells that withstand chemotherapy during cancer chemoimmunotherapy

Yan, Y., Cao, S., Liu, X., Harrington, S. M., Bindeman, W. E., Adjei, A. A., Jang, J. S., Jen, J., Li, Y., Chanana, P., Mansfield, A. S., Park, S. S., Markovic, S. N., Dronca, R. S. & Dong, H., Apr 19 2018, In : JCI insight. 3, 8

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

Data collection of patient outcomes: One institution's experience

Whitaker, T. J., Mayo, C. S., Ma, D. J., Haddock, M. G., Miller, R. C., Corbin, K. S., Neben-Wittich, M., Leenstra, J. L., Laack, N. N., Fatyga, M., Schild, S. E., Vargas, C. E., Tzou, K. S., Hadley, A. R., Buskirk, S. J. & Foote, R. L., Mar 1 2018, In : Journal of Radiation Research. 59, p. i19-i24

Research output: Contribution to journalArticle

Distinctive epigenomes characterize glioma stem cells and their response to differentiation cues

Zhou, D., Alver, B. M., Li, S., Hlady, R. A., Thompson, J. J., Schroeder, M. A., Lee, J. H., Qiu, J., Schwartz, P. H., Sarkaria, J. N. & Robertson, K. D., Mar 27 2018, In : Genome biology. 19, 1, 43.

Research output: Contribution to journalArticle

15 Scopus citations
Open Access

Drug and disease signature integration identifies synergistic combinations in glioblastoma

Stathias, V., Jermakowicz, A. M., Maloof, M. E., Forlin, M., Walters, W., Suter, R. K., Durante, M. A., Williams, S. L., Harbour, J. W., Volmar, C. H., Lyons, N. J., Wahlestedt, C., Graham, R. M., Ivan, M. E., Komotar, R. J., Sarkaria, J. N., Subramanian, A., Golub, T. R., Schürer, S. C. & Ayad, N. G., Dec 1 2018, In : Nature Communications. 9, 1, 5315.

Research output: Contribution to journalArticle

10 Scopus citations

Durable response of early-stage breast cancer to bilateral definitive SBRT in a medically inoperable patient

Gao, R. W., Park, S. S., Jakub, J. W., Hieken, T. J., Conners, A. L., Neal, L., Pruthi, S., Corbin, K. S., Yan, E. S., Mutter, R. & Stish, B. J., Jan 1 2018, (Accepted/In press) In : Practical Radiation Oncology.

Research output: Contribution to journalArticle

Effect of Inorganic Nitrite vs Placebo on Exercise Capacity among Patients with Heart Failure with Preserved Ejection Fraction: The INDIE-HFpEF Randomized Clinical Trial

Borlaug, B. A., Anstrom, K. J., Lewis, G. D., Shah, S. J., Levine, J. A., Koepp, G. A., Givertz, M. M., Felker, G. M., Lewinter, M. M., Mann, D. L., Margulies, K. B., Smith, A. L., Tang, W. H. W., Whellan, D. J., Chen, H. H., Davila-Roman, V. G., McNulty, S., Desvigne-Nickens, P., Hernandez, A. F., Braunwald, E. & 1 others, Redfield, M. M., Nov 6 2018, In : JAMA - Journal of the American Medical Association. 320, 17, p. 1764-1773 10 p.

Research output: Contribution to journalArticle

35 Scopus citations

Efficacy of the MDM2 inhibitor SAR405838 in glioblastoma is limited by poor distribution across the blood–brain barrier

Kim, M., Ma, D. J., Calligaris, D., Zhang, S., Feathers, R. W., Vaubel, R. A., Meaux, I., Mladek, A. C., Parrish, K. E., Jin, F., Barriere, C., Debussche, L., Watters, J., Tian, S., Decker, P. A., Eckel-Passow, J. E., Kitange, G. J., Johnson, A. J., Parney, I. F., Anastasiadis, P. Z. & 3 others, Agar, N. Y. R., Elmquist, W. F. & Sarkaria, J. N., Sep 1 2018, In : Molecular Cancer Therapeutics. 17, 9, p. 1893-1901 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Ewing sarcoma and desmoplastic small round cell tumor

Ahmed, S. K., Laskar, S. & Laack, N. N., Jan 1 2018, Pediatric Oncology. 9783319435442 ed. Springer Verlag, p. 3-20 18 p. (Pediatric Oncology; no. 9783319435442).

Research output: Chapter in Book/Report/Conference proceedingChapter

Extended-Field Chemoradiation Therapy for Definitive Treatment of Anal Canal Squamous Cell Carcinoma Involving the Para-Aortic Lymph Nodes

Holliday, E. B., Lester, S. C., Harmsen, W. S., Eng, C., Haddock, M., Krishnan, S., Das, P. & Hallemeier, C., Jan 1 2018, (Accepted/In press) In : International Journal of Radiation Oncology Biology Physics.

Research output: Contribution to journalArticle

3 Scopus citations

External beam radiation therapy for advanced/unresectable malignant paraganglioma and pheochromocytoma

Breen, W., Bancos, I., Young, W. F., Bible, K. C., Laack, N. N., Foote, R. L. & Hallemeier, C., Jan 1 2018, (Accepted/In press) In : Advances in Radiation Oncology.

Research output: Contribution to journalArticle

8 Scopus citations

Gastrointestinal Cancers-Carving Out the Optimal Local Therapies in the Gastrointestinal Tract

Olsen, J. R., Murphy, J. D., Huguet, F., Hallemeier, C., Apisarnthanarax, S. & Jabbour, S. K., Oct 1 2018, In : International journal of radiation oncology, biology, physics. 102, 2, p. 233-242 10 p.

Research output: Contribution to journalComment/debate

Gemcitabine-Induced Radiation Recall Myositis: Case Report and Review of the Literature

Ravishankar, A., Park, S. S., Olivier, K. R. & Corbin, K. S., Mar 27 2018, (Accepted/In press) In : Case Reports in Oncology. p. 168-178 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

H3.3K27M mutant proteins reprogram epigenome by sequestering the PRC2 complex to poised enhancers

Fang, D., Gan, H., Cheng, L., Lee, J. H., Zhou, H., Sarkaria, J. N., Daniels, D. & Zhang, Z., Jun 22 2018, In : eLife. 7, e36696.

Research output: Contribution to journalArticle

19 Scopus citations

Hypoxia-inducible factor 2α: A novel target in gliomas

Renfrow, J. J., Soike, M. H., Debinski, W., Ramkissoon, S. H., Mott, R. T., Frenkel, M. B., Sarkaria, J. N., Lesser, G. J. & Strowd, R. E., Sep 1 2018, In : Future Medicinal Chemistry. 10, 18, p. 2227-2236 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Identification of Recurrence Sites Following Post-Prostatectomy Treatment for Prostate Cancer Using 11C-Choline Positron Emission Tomography and Multiparametric Pelvic Magnetic Resonance Imaging

Nehra, A., Parker, W. P., Haloi, R., Park, S. S., Mynderse, L. A., Lowe, V., Davis, B. J., Quevedo, J. F., Johnson, G. B., Kwon, E. D. & Karnes, R. J., Jan 1 2018, (Accepted/In press) In : Journal of Urology.

Research output: Contribution to journalArticle

5 Scopus citations
1 Scopus citations

Influence of hyaluronic acid transitions in tumor microenvironment on glioblastoma malignancy and invasive behavior

Chen, J. W. E., Pedron, S., Shyu, P., Hu, Y., Sarkaria, J. N. & Harley, B. A. C., Jun 26 2018, In : Frontiers in Materials. 5, 39.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Initial experience with intensity modulated proton therapy for intact, clinically localized pancreas cancer: Clinical implementation, dosimetric analysis, acute treatment-related adverse events, and patient-reported outcomes

Jethwa, K. R., Tryggestad, E. J., Whitaker, T. J., Giffey, B. T., Kazemba, B. D., Neben-Wittich, M. A., Merrell, K. W., Haddock, M. & Hallemeier, C., Jan 1 2018, (Accepted/In press) In : Advances in Radiation Oncology.

Research output: Contribution to journalArticle

6 Scopus citations

In Reply to Garden

Routman, D. M., Foote, R. L., Ma, D. J., Patel, S. H. & Hinni, M. L., Apr 1 2018, In : International Journal of Radiation Oncology Biology Physics. 100, 5, p. 1091-1094 4 p.

Research output: Contribution to journalLetter

Integrated mapping of pharmacokinetics and pharmacodynamics in a patient-derived xenograft model of glioblastoma

Randall, E. C., Emdal, K. B., Laramy, J. K., Kim, M., Roos, A., Calligaris, D., Regan, M. S., Gupta, S. K., Mladek, A. C., Carlson, B. L., Johnson, A. J., Lu, F. K., Xie, X. S., Joughin, B. A., Reddy, R. J., Peng, S., Abdelmoula, W. M., Jackson, P. R., Kolluri, A., Kellersberger, K. A. & 8 others, Agar, J. N., Lauffenburger, D. A., Swanson, K., Tran, N., Elmquist, W. F., White, F. M., Sarkaria, J. N. & Agar, N. Y. R., Dec 1 2018, In : Nature Communications. 9, 1, 4904.

Research output: Contribution to journalArticle

13 Scopus citations

Is the blood-brain barrier really disrupted in all glioblastomas? A critical assessment of existing clinical data

Sarkaria, J. N., Hu, L. S., Parney, I. F., Pafundi, D. H., Brinkmann, D. H., Laack, N. N., Giannini, C., Burns, T. C., Kizilbash, S. H., Laramy, J. K., Swanson, K. R., Kaufmann, T. J., Brown, P. D., Agar, N. Y. R., Galanis, E., Buckner, J. C. & Elmquist, W. F., Jan 22 2018, In : Neuro-oncology. 20, 2, p. 184-191 8 p.

Research output: Contribution to journalArticle

68 Scopus citations

Low dose rate prostate brachytherapy

Stish, B. J., Davis, B. J., Mynderse, L. A., McLaren, R. H., Deufel, C. L. & Choo, R., Jun 1 2018, In : Translational Andrology and Urology. 7, 3, p. 341-356 16 p.

Research output: Contribution to journalReview article

5 Scopus citations

LPA signaling is regulated through the primary cilium: A novel target in glioblastoma

Loskutov, Y. V., Griffin, C. L., Marinak, K. M., Bobko, A., Margaryan, N. V., Geldenhuys, W. J., Sarkaria, J. N. & Pugacheva, E. N., Mar 1 2018, In : Oncogene. 37, 11, p. 1457-1471 15 p.

Research output: Contribution to journalArticle

13 Scopus citations

Magnitude of benefit for adjuvant radiotherapy following minimally invasive surgery in intermediate to high risk HPV-positive oropharyngeal squamous cell carcinoma

Pasalic, D., Funk, R. K., García, J. J., Price, D. L., Price, K. A., Harmsen, W. S., Patel, S. H., Young, G. D., Foote, R. L., Moore, E. J. & Ma, D. J., Jul 1 2018, In : Oral Oncology. 82, p. 181-186 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Modeling the diffusion of D-2-hydroxyglutarate from IDH1 mutant gliomas in the central nervous system

Linninger, A., Hartung, G. A., Liu, B. P., Mirkov, S., Tangen, K., Lukas, R. V., Unruh, D., David James, C., Sarkaria, J. N. & Horbinski, C., Jan 1 2018, In : Neuro-Oncology. 20, 9, p. 1197-1206 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Modern reirradiation for recurrent gliomas can safely delay tumor progression

Youland, R. S., Lee, J. Y., Kreofsky, C. R., Brown, P. D., Uhm, J. H. & Laack, N. N., Mar 2 2018, In : Neuro-Oncology Practice. 5, 1, p. 46-55 10 p.

Research output: Contribution to journalArticle

Molecular and structural traits of insulin receptor substrate 1/LC3 nuclear structures and their role in autophagy control and tumor cell survival

Lassak, A., Dean, M., Wyczechowsk, D., Wilk, A., Marrero, L., Trillo-Tinoco, J., Hamid Boulares, A., Sarkaria, J. N., Valle, L. D., Peruzzi, F., Ochoa, A. & Reiss, K., May 1 2018, In : Molecular and Cellular Biology. 38, 10, e00608.

Research output: Contribution to journalArticle

2 Scopus citations

Myoepithelioma of Soft Tissues A Single Institution Retrospective Case Series

Domingo-Musibay, E., Oliveira, A. M., Okuno, S. H., Petersen, I. A., Rose, P. S. & Robinson, S. I., Jan 1 2018, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 41, 4, p. 357-361 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

NCCN guidelines ® insights: Head and neck cancers, version 1.2018 featured updates to the NCCN guidelines

Colevas, A. D., Yom, S. S., Pfister, D. G., Spencer, S., Adelstein, D., Adkins, D., Brizel, D. M., Burtness, B., Busse, P. M., Caudell, J. J., Cmelak, A. J., Eisele, D. W., Fenton, M., Foote, R. L., Gilbert, J., Gillison, M. L., Haddad, R. I., Hicks, W. L., Hitchcock, Y. J., Jimeno, A. & 15 others, Leizman, D., Maghami, E., Mell, L. K., Mittal, B. B., Pinto, H. A., Ridge, J. A., Rocco, J., Rodriguez, C. P., Shah, J. P., Weber, R. S., Witek, M., Worden, F., Zhen, W., Burns, J. L. & Darlow, S. D., May 1 2018, In : JNCCN Journal of the National Comprehensive Cancer Network. 16, 5, p. 479-490 12 p.

Research output: Contribution to journalReview article

80 Scopus citations

Necessity of multimodal treatment of acromegaly and outcomes

Donegan, D. M., Iñiguez-Ariza, N., Sharma, A., Nippoldt, T., Young, W. F., Van Gompel, J., Atkinson, J., Meyer, F., Pollock, B., Natt, N., Laack, N. N. & Erickson, D., Jul 1 2018, In : Endocrine Practice. 24, 7, p. 668-676 9 p.

Research output: Contribution to journalArticle

Nomogram prediction of overall survival for patients with non-small-cell lung cancer incorporating pretreatment peripheral blood markers

Xie, D., Allen, M. S., Marks, R. S., Jiang, G., Sun, Z. D., Nichols, F., Zhang, M., Chen, C., Aubry, M. C., Jatoi, A., Garces, Y. I., Mansfield, A., Wigle, D. A., Molina, J. R., Deschamps, C. & Yang, P., Jun 1 2018, In : European Journal of Cardio-thoracic Surgery. 53, 6, p. 1214-1222 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Patient-reported outcomes of catheter-based accelerated partial breast brachytherapy and whole breast irradiation, a single institution experience

Jethwa, K. R., Kahila, M. M., Mara, K. C., Harmsen, W. S., Routman, D. M., Pumper, G. M., Corbin, K. S., Sloan, J. A., Ruddy, K. J., Hieken, T. J., Park, S. S. & Mutter, R. W., May 1 2018, In : Breast Cancer Research and Treatment. 169, 1, p. 189-196 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Percutaneous image-guided nodal biopsy after 11C-Choline PET/CT for biochemically recurrent prostate cancer: Imaging predictors of disease and clinical implications

Welch, B. T., Packard, A. T., Atwell, T. D., Johnson, G. B., Lowe, V., Karnes, R. J., Mynderse, L. A., Gunderson, T. M., Park, S. S., Stish, B. J., Evans, J. D., Kwon, E. D., Davis, B. J. & Nathan, M. A., Jan 1 2018, (Accepted/In press) In : Advances in Radiation Oncology.

Research output: Contribution to journalArticle

1 Scopus citations

Permanent prostate brachytherapy monotherapy with I-125 for low- and intermediate-risk prostate cancer: Outcomes in 974 patients

Routman, D. M., Funk, R. K., Stish, B. J., Mynderse, L. A., Wilson, T. M., McLaren, R., Harmsen, W. S., Mara, K., Deufel, C. L., Furutani, K. M., Haddock, M., Pisansky, T. M., Choo, C. R. & Davis, B. J., Jan 1 2018, (Accepted/In press) In : Brachytherapy.

Research output: Contribution to journalArticle

5 Scopus citations

Phantom Verification of AAA and Acuros Dose Calculations for Lung Cancer: Do Tumor Size and Regression Matter?

Shiraishi, S., Fong de los Santos, L. E., Antolak, J. A., Olivier, K. R., Garces, Y. I., Park, S. S. & Grams, M. P., Jan 1 2018, (Accepted/In press) In : Practical Radiation Oncology.

Research output: Contribution to journalArticle

Pharmacokinetic assessment of cooperative efflux of the multitargeted kinase inhibitor ponatinib across the blood-brain barrier

Laramy, J. K., Kim, M., Parrish, K. E., Sarkaria, J. N. & Elmquist, W. F., May 1 2018, In : Journal of Pharmacology and Experimental Therapeutics. 365, 2, p. 249-261 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

Phase 1/2 trial of temsirolimus and sorafenib in the treatment of patients with recurrent glioblastoma: North Central Cancer Treatment Group Study/Alliance N0572

Schiff, D., Jaeckle, K. A., Anderson, S. K., Galanis, E., Giannini, C., Buckner, J. C., Stella, P., Flynn, P. J., Erickson, B. J., Schwerkoske, J. F., Kaluza, V., Twohy, E., Dancey, J., Wright, J. & Sarkaria, J. N., Apr 1 2018, In : Cancer. 124, 7, p. 1455-1463 9 p.

Research output: Contribution to journalArticle

8 Scopus citations