Physiology & Biomedical Engineering

Research Output 1968 2019

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2019

Acoustoelasticity Analysis of Transient Waves for Non-Invasive In Vivo Assessment of Urinary Bladder

Bayat, M., Adabi, S., Kumar, V., Gregory, A., Webb, J., Denis, M., Kim, B., Singh, A., Mynderse, L., Husmann, D., Alizad, A. & Fatemi, M., Dec 1 2019, In : Scientific reports. 9, 1, 2441.

Research output: Contribution to journalArticle

Open Access
Urinary Bladder
Elasticity
Neurogenic Urinary Bladder
Elastic Modulus
Fourier Analysis

An Ultrasound Vibro-Elastography Technique for Assessing Papilledema

Zhou, B., Chen, J., Kazemi, A., Sit, A. J. & Zhang, X., Jan 1 2019, In : Ultrasound in Medicine and Biology.

Research output: Contribution to journalArticle

Elasticity Imaging Techniques
Papilledema
hypertension
Sclera
Pseudotumor Cerebri

A real-time color doppler marker for echocardiographic guidance of an acoustically active extracorporeal membrane oxygenation cannula

Belohlavek, M., Katayama, M., Vaitkus, V. V., Kumar, V., Fatemi, M., Grabham, J. & Sandweiss, B., Jan 1 2019, In : Journal of Ultrasound in Medicine. 38, 7, p. 1875-1885 11 p.

Research output: Contribution to journalArticle

Extracorporeal Membrane Oxygenation
Color
Artifacts
Noise
Ultrasonography

Assessment of pulsatile insulin secretion derived from peripheral plasma C-peptide concentrations by nonparametric stochastic deconvolution

Laurenti, M. C., Vella, A., Varghese, R. T., Andrews, J. C., Sharma, A., Kittah, N. E., Rizza, R. A., Matveyenko, A. V., De Nicolao, G., Cobelli, C. & Dalla Man, C., May 1 2019, In : American journal of physiology. Endocrinology and metabolism. 316, 5, p. E687-E694

Research output: Contribution to journalArticle

C-Peptide
Insulin
Hepatic Veins
Type 2 Diabetes Mellitus
Liver
2 Citations (Scopus)

Automated Droplet-Based Microfluidic Platform for Multiplexed Analysis of Biochemical Markers in Small Volumes

Cedillo-Alcantar, D. F., Han, Y. D., Choi, J., Garcia-Cordero, J. L. & Revzin, A., Apr 16 2019, In : Analytical Chemistry. 91, 8, p. 5133-5141 9 p.

Research output: Contribution to journalArticle

Microfluidics
Assays
Bile Acids and Salts
L-Lactate Dehydrogenase
Glucose

Calcium sensing receptor in developing human airway smooth muscle

Roesler, A. M., Wicher, S. A., Ravix, J., Britt, R. J., Manlove, L., Teske, J. J., Cummings, K., Thompson, M. A., Farver, C., MacFarlane, P., Pabelick, C. M. & Prakash, Y. S., Jan 1 2019, (Accepted/In press) In : Journal of Cellular Physiology.

Research output: Contribution to journalArticle

Calcium-Sensing Receptors
N-(2-chlorophenylpropyl)-1-(3-methoxyphenyl)ethylamine
Smooth Muscle
Muscle
Lung

Cardiac Valve Bioreactor for Physiological Conditioning and Hydrodynamic Performance Assessment

Tefft, B. J., Choe, J. A., Young, M. D., Hennessy, R. S., Morse, D. W., Bouchard, J. A., Hedberg, H. J., Consiglio, J. F., Dragomir Daescu, M. D., Simari, R. D. & Lerman, A., Mar 15 2019, In : Cardiovascular Engineering and Technology. 10, 1, p. 80-94 15 p.

Research output: Contribution to journalArticle

Heart Valves
Bioreactors
Hydrodynamics
Tissue
Pressure

Caveolin-1 scaffolding domain peptide prevents hyperoxia-induced airway remodeling in a neonatal mouse model

Vogel, E. R., Manlove, L. J., Kuipers, I., Thompson, M. A., Fang, Y. H., Freeman, M. R., Britt, R. J., Faksh, A., Yang, B., Prakash, Y. S. & Pabelick, C. M., Jul 1 2019, In : American journal of physiology. Lung cellular and molecular physiology. 317, 1, p. L99-L108

Research output: Contribution to journalArticle

Airway Remodeling
Hyperoxia
Caveolin 1
Smooth Muscle
Lung Compliance

CBX5/G9a/H3K9me-mediated gene repression is essential to fibroblast activation during lung fibrosis

Ligresti, G., Caporarello, N., Meridew, J. A., Jones, D. L., Tan, Q., Choi, K. M., Haak, A. J., Aravamudhan, A., Roden, A., Prakash, Y. S., Lomberk, G., Urrutia, R. A. & Tschumperlin, D. J., Jan 1 2019, In : JCI Insight. 4, 12, e127111.

Research output: Contribution to journalArticle

Open Access
Fibrosis
Fibroblasts
Lung
Genes
Epigenomics
10 Citations (Scopus)

Charting cellular identity during human in vitro β-cell differentiation

Veres, A., Faust, A. L., Bushnell, H. L., Engquist, E. N., Kenty, J. H. R., Harb, G., Poh, Y. C., Sintov, E., Gürtler, M., Pagliuca, F. W., Peterson, Q. & Melton, D. A., May 16 2019, In : Nature. 569, 7756, p. 368-373 6 p.

Research output: Contribution to journalArticle

Cell Differentiation
Endocrine Cells
Islets of Langerhans
Stem Cells
Enterochromaffin Cells

Cloning, function, and localization of human, canine, and Drosophila ZIP10 (SLC39A10), a Zn2+ transporter

Landry, G. M., Furrow, E., Holmes, H. L., Hirata, T., Kato, A., Williams, P., Strohmaier, K., Gallo, C. J. R., Chang, M., Pandey, M., Jiang, H., Bansal, A., Franz, M. C., Montalbetti, N., Alexander, M. P., Cabrero, P., Dow, J. A. T., DeGrado, T. R. & Romero, M. F., Feb 1 2019, In : American journal of physiology. Renal physiology. 316, 2, p. F263-F273

Research output: Contribution to journalArticle

Drosophila
Canidae
Organism Cloning
Kidney
Malpighian Tubules

Debiasing-based noise suppression for ultrafast ultrasound microvessel imaging

Huang, C., Song, P., Gong, P., Trazasko, J. D., Manduca, A. & Chen, S. D., Aug 1 2019, In : IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. 66, 8, p. 1281-1291 11 p., 8720262.

Research output: Contribution to journalArticle

Acoustic noise
Ultrasonics
retarding
Imaging techniques
decomposition
4 Citations (Scopus)

Diaphragm muscle function following midcervical contusion injury in rats

Khurram, O. U., Fogarty, M. J., Rana, S., Vang, P., Sieck, G. C. & Mantilla, C. B., Jan 1 2019, In : Journal of applied physiology (Bethesda, Md. : 1985). 126, 1, p. 221-230 10 p.

Research output: Contribution to journalArticle

Contusions
Diaphragm
Muscles
Wounds and Injuries
Motor Neurons

Diaphragm neuromuscular transmission failure in aged rats

Fogarty, M. J., Porras, M. A. G., Mantilla, C. B. & Sieck, G. C., Jan 1 2019, In : Journal of Neurophysiology. 122, 1, p. 93-104 12 p.

Research output: Contribution to journalArticle

Diaphragm
Muscles
Neuromuscular Junction
Sarcopenia
Phrenic Nerve
1 Citation (Scopus)

Direct repression of anoctamin 1 (ANO1) gene transcription by Gli proteins

Mazzone, A., Gibbons, S. J., Eisenman, S. T., Strege, P. R., Zheng, T., D'Amato, M., Ordog, T., Fernandez-Zapico, M. E. & Farrugia, G., May 1 2019, In : FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33, 5, p. 6632-6642 11 p.

Research output: Contribution to journalArticle

Transcription
Genes
Polymorphism
Hylobates
Kidney

Effect of a thin fluid layer on surface wave speed measurements: A lung phantom study

Zhou, J. & Zhang, X., May 1 2019, In : Journal of Ultrasound in Medicine. 38, 5, p. 1361-1365 5 p.

Research output: Contribution to journalArticle

Porifera
Elasticity Imaging Techniques
Lung
Gels
Elastic Tissue

Enhanced and controlled chromatin extraction from FFPE tissues and the application to ChIP-seq

Zhong, J., Ye, Z., Clark, C. R., Lenz, S. W., Nguyen, J. H., Yan, H. D., Robertson, K. D., Farrugia, G., Zhang, Z., Ordog, T. & Lee, J. H., Mar 29 2019, In : BMC genomics. 20, 1, 249.

Research output: Contribution to journalArticle

Paraffin
Formaldehyde
Chromatin
Epigenomics
Temperature

Estimation of manual wheelchair-based activities in the free-living environment using a neural network model with inertial body-worn sensors

Fortune, E., Cloud-Biebl, B. A., Madansingh, S. I., Ngufor, C., Van Straaten, M. G., Goodwin, B. M., Murphree, D. H., Zhao, K. D. & Morrow, M. M. M., Jan 1 2019, (Accepted/In press) In : Journal of Electromyography and Kinesiology.

Research output: Contribution to journalArticle

Wheelchairs
Neural Networks (Computer)
Spinal Cord Injuries
Activities of Daily Living
Shoulder Pain

Evaluation of materials used for vascular anastomoses using shear wave elastography

Bernal, M., Sen, I. & Urban, M. W., Mar 21 2019, In : Physics in medicine and biology. 64, 7, 075001.

Research output: Contribution to journalArticle

Cryogels
Elasticity Imaging Techniques
Polyvinyl Alcohol
Polyethylene Terephthalates
Blood Vessels
2 Citations (Scopus)

Evolution and Functional Differentiation of the Diaphragm Muscle of Mammals

Fogarty, M. J. & Sieck, G. C., Mar 14 2019, In : Comprehensive Physiology. 9, 2, p. 715-766 52 p.

Research output: Contribution to journalArticle

Diaphragm
Mammals
Thoracic Cavity
Muscles
Abdominal Cavity
1 Citation (Scopus)

Fabrication of composite microfluidic devices for local control of oxygen tension in cell cultures

Gao, Y., Stybayeva, G. & Revzin, A., Jan 1 2019, In : Lab on a Chip. 19, 2, p. 306-315 10 p.

Research output: Contribution to journalArticle

Lab-On-A-Chip Devices
Cell culture
Microfluidics
Cell Culture Techniques
Oxygen
2 Citations (Scopus)

Frequency-dependent lipid raft uptake at rat diaphragm muscle axon terminals

Gonzalez Porras, M. A., Fogarty, M. J., Gransee, H. M., Sieck, G. C. & Mantilla, C. B., Jan 1 2019, In : Muscle and Nerve.

Research output: Contribution to journalArticle

Cholera Toxin
Presynaptic Terminals
Diaphragm
Lipids
Muscles

Gap-filling method for suppressing grating lobes in ultrasound imaging: Theory and simulation results

Kim, B. H., Kumar, V., Alizad, A. & Fatemi, M., Mar 1 2019, In : Journal of the Acoustical Society of America. 145, 3, p. EL236-EL242

Research output: Contribution to journalArticle

Open Access
lobes
gratings
simulation
artifacts
echoes

HDAC3 restrains CD8-lineage genes to maintain a bi-potential state in CD4+CD8+ thymocytes for CD4-lineage commitment

Philips, R. L., Lee, J. H., Gaonkar, K., Chanana, P., Chung, J. Y., Romero Arocha, S. R., Schwab, A., Ordog, T. & Shapiro, V. M., Jan 18 2019, In : eLife. 8

Research output: Contribution to journalArticle

Thymocytes
Genes
T-cells
T-Lymphocytes
Acetylation
4 Citations (Scopus)

Hyperoxia-induced cellular senescence in fetal airway smooth muscle cells

Parikh, P., Britt, R. J., Manlove, L. J., Wicher, S. A., Roesler, A., Ravix, J., Teske, J., Thompson, M. A., Sieck, G. C., Kirkland, J. L., LeBrasseur, N. K., Tschumperlin, D. J., Pabelick, C. M. & Prakash, Y. S., Jan 1 2019, In : American journal of respiratory cell and molecular biology. 61, 1, p. 51-60 10 p.

Research output: Contribution to journalArticle

Hyperoxia
Cell Aging
Smooth Muscle Myocytes
Muscle
Cells
3 Citations (Scopus)

Impact of sarcopenia on diaphragm muscle fatigue

Fogarty, M. J., Mantilla, C. B. & Sieck, G. C., Jan 1 2019, In : Experimental physiology.

Research output: Contribution to journalArticle

Sarcopenia
Muscle Fatigue
Diaphragm
Muscles
Fatigue

In vivo assessment of the mechanical properties of crystalline lenses in a rabbit model using ultrasound elastography: Effects of ultrasound frequency and age

Wang, Q., Zhu, Y., Shao, M., Lin, H., Chen, S., Chen, X., Alizad, A., Fatemi, M. & Zhang, X., Jul 1 2019, In : Experimental Eye Research. 184, p. 258-265 8 p.

Research output: Contribution to journalArticle

Elasticity Imaging Techniques
Crystalline Lens
Rabbits
Lenses
Biomarkers

Late-life time-restricted feeding and exercise differentially alter healthspan in obesity

Schafer, M. J., Mazula, D. L., Brown, A. K., White, T. A., Atkinson, E., Pearsall, V. M., Aversa, Z., Verzosa, G. C., Smith, L. A., Matveyenko, A. V., Miller, J. D. & LeBrasseur, N. K., Aug 1 2019, In : Aging Cell. 18, 4, e12966.

Research output: Contribution to journalArticle

Open Access
Obesity
Activities of Daily Living
Body Composition
Pathology
Health Priorities
12 Citations (Scopus)

Length-independent telomere damage drives post-mitotic cardiomyocyte senescence

Anderson, R., Lagnado, A., Maggiorani, D., Walaszczyk, A., Dookun, E., Chapman, J., Birch, J., Salmonowicz, H., Ogrodnik, M., Jurk, D., Proctor, C., Correia-Melo, C., Victorelli, S., Fielder, E., Berlinguer-Palmini, R., Owens, A., Greaves, L. C., Kolsky, K. L., Parini, A., Douin-Echinard, V. & 14 others, LeBrasseur, N. K., Arthur, H. M., Tual-Chalot, S., Schafer, M. J., Roos, C. M., Miller, J. D., Robertson, N., Mann, J., Adams, P. D., Tchkonia, T., Kirkland, J. L., Mialet-Perez, J., Richardson, G. D. & Passos, J., Mar 1 2019, In : EMBO Journal. 38, 5, e100492.

Research output: Contribution to journalArticle

Open Access
Telomere
Cardiac Myocytes
Aging of materials
Telomere Shortening
Phenotype
1 Citation (Scopus)

Lung US surface wave elastography in interstitial lung disease staging

Zhou, B., Bartholmai, B. J., Kalra, S., Osborn, T. & Zhang, X., May 1 2019, In : Radiology. 291, 2, p. 479-484 6 p.

Research output: Contribution to journalArticle

Elasticity Imaging Techniques
Interstitial Lung Diseases
Lung
Healthy Volunteers
Fibrosis

Maternal high-fat diet alters lung development and function in the offspring

Heyob, K. M., Mieth, S., Sugar, S. S., Graf, A. E., Lallier, S. W., Britt, R. J. & Rogers, L. K., Aug 1 2019, In : American journal of physiology. Lung cellular and molecular physiology. 317, 2, p. L167-L174

Research output: Contribution to journalArticle

High Fat Diet
Mothers
Lung
Diet
Obesity
2 Citations (Scopus)

Mechanical Stretch Increases Expression of CXCL1 in Liver Sinusoidal Endothelial Cells to Recruit Neutrophils, Generate Sinusoidal Microthombi, and Promote Portal Hypertension

Hilscher, M. B., Sehrawat, T., Arab, J. P., Zeng, Z., Gao, J., Liu, M., Kostallari, E., Gao, Y., Simonetto, D., Yaqoob, U., Cao, S., Revzin, A., Beyder, A., Wang, R. A., Kamath, P. S., Kubes, P. & Shah, V., Jul 1 2019, In : Gastroenterology. 157, 1, p. 193-209.e9

Research output: Contribution to journalArticle

Portal Hypertension
Neutrophils
Endothelial Cells
Liver
RNA Sequence Analysis

Microencapsulated Immunoassays for Detection of Cytokines in Human Blood

Rahimian, A., Siltanen, C., Feyzizarnagh, H., Escalante, P. & Revzin, A., Jan 1 2019, In : ACS Sensors.

Research output: Contribution to journalArticle

immunoassay
interferon
Interferons
blood
Blood

mTORC1 to AMPK switching underlies β-cell metabolic plasticity during maturation and diabetes

Jaafar, R., Tran, S., Shah, A., Sun, G., Valdearcos, M., Marchetti, P., Masini, M., Swisa, A., Giacometti, S., Bernal-Mizrachi, E., Matveyenko, A. V., Hebrok, M., Dor, Y., Rutter, G. A., Koliwad, S. K. & Bhushan, A., Jul 2 2019, In : The Journal of clinical investigation. 130

Research output: Contribution to journalArticle

Open Access
Adenosine Monophosphate
Protein Kinases
Insulin
Metabolic Engineering
Phenotype
1 Citation (Scopus)

Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH)—phase II: rupture risk assessment

Berg, P., Voß, S., Janiga, G., Saalfeld, S., Bergersen, A. W., Valen-Sendstad, K., Bruening, J., Goubergrits, L., Spuler, A., Chiu, T. L., Tsang, A. C. O., Copelli, G., Csippa, B., Paál, G., Závodszky, G., Detmer, F. J., Chung, B. J., Cebral, J. R., Fujimura, S., Takao, H. & 24 others, Karmonik, C., Elias, S., Cancelliere, N. M., Najafi, M., Steinman, D. A., Pereira, V. M., Piskin, S., Finol, E. A., Pravdivtseva, M., Velvaluri, P., Rajabzadeh-Oghaz, H., Paliwal, N., Meng, H., Seshadhri, S., Venguru, S., Shojima, M., Sindeev, S., Frolov, S., Qian, Y., Wu, Y. A., Carlson, K. D., Kallmes, D. F., Dragomir Daescu, M. D. & Beuing, O., Jan 1 2019, In : International Journal of Computer Assisted Radiology and Surgery.

Research output: Contribution to journalArticle

Hemodynamics
Risk assessment
Aneurysm
Rupture
Anatomy

Muscularis Propria Macrophages Alter the Proportion of Nitrergic but Not Cholinergic Gastric Myenteric Neurons

Cipriani, G., Terhaar, M. L., Eisenman, S. T., Ji, S., Linden, D. R., Wright, A. M., Sha, L., Ordog, T., Szurszewski, J. H., Gibbons, S. J. & Farrugia, G., Jan 1 2019, In : CMGH.

Research output: Contribution to journalArticle

Open Access
Cholinergic Agents
Stomach
Macrophages
Neurons
clutter
vessels
Thyroid Gland
blood flow
Blood Vessels
2 Citations (Scopus)

Non-local based denoising framework for in vivo contrast-free ultrasound microvessel imaging

Adabi, S., Ghavami, S., Fatemi, M. & Alizad, A., Jan 2 2019, In : Sensors (Switzerland). 19, 2, 245.

Research output: Contribution to journalArticle

Microvessels
Image quality
Noise
Ultrasonography
Visualization
1 Citation (Scopus)

Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis

Ogrodnik, M., Zhu, Y., Langhi, L. G. P., Tchkonia, T., Krüger, P., Fielder, E., Victorelli, S., Ruswhandi, R. A., Giorgadze, N., Pirtskhalava, T., Podgorni, O., Enikolopov, G., Johnson, K. O., Xu, M., Inman, C., Palmer, A. K., Schafer, M., Weigl, M., Ikeno, Y., Burns, T. C. & 4 others, Passos, J., von Zglinicki, T., Kirkland, J. L. & Jurk, D., Jan 1 2019, (Accepted/In press) In : Cell Metabolism.

Research output: Contribution to journalArticle

Manuscripts
Cell Aging
Neurogenesis
Publications
Anxiety
12 Citations (Scopus)

Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis

Ogrodnik, M., Zhu, Y., Langhi, L. G. P., Tchkonia, T., Krüger, P., Fielder, E., Victorelli, S., Ruswhandi, R. A., Giorgadze, N., Pirtskhalava, T., Podgorni, O., Enikolopov, G., Johnson, K. O., Xu, M., Inman, C., Palmer, A. K., Schafer, M., Weigl, M., Ikeno, Y., Burns, T. C. & 4 others, Passos, J., von Zglinicki, T., Kirkland, J. L. & Jurk, D., May 7 2019, In : Cell Metabolism. 29, 5, p. 1061-1077.e8

Research output: Contribution to journalArticle

Open Access
Cell Aging
Neurogenesis
Anxiety
Obesity
Obese Mice

Optimizing Accuracy of Proximal Femur Elastic Modulus Equations

Rezaei, A., Carlson, K. D., Giambini, H., Javid, S. & Dragomir Daescu, M. D., Jan 1 2019, In : Annals of Biomedical Engineering.

Research output: Contribution to journalArticle

Ashes
Elastic moduli
Tomography
Finite element method
Stiffness

PGC1α repression in IPF fibroblasts drives a pathologic metabolic, secretory and fibrogenic state

Caporarello, N., Meridew, J. A., Jones, D. L., Tan, Q., Haak, A. J., Choi, K. M., Manlove, L. J., Prakash, Y. S., Tschumperlin, D. J. & Ligresti, G., Jan 1 2019, In : Thorax.

Research output: Contribution to journalArticle

Open Access
Idiopathic Pulmonary Fibrosis
Fibroblasts
rosiglitazone
Fibrosis
Smegmamorpha
4 Citations (Scopus)

Pharmacological clearance of senescent cells improves survival and recovery in aged mice following acute myocardial infarction

Walaszczyk, A., Dookun, E., Redgrave, R., Tual-Chalot, S., Victorelli, S., Spyridopoulos, I., Owens, A., Arthur, H. M., Passos, J. & Richardson, G. D., Jun 1 2019, In : Aging Cell. 18, 3, e12945.

Research output: Contribution to journalArticle

Open Access
Cell Survival
Myocardial Infarction
Pharmacology
Cardiac Myocytes
Coronary Artery Disease
2 Citations (Scopus)

Phases of Metabolic and Soft Tissue Changes in Months Preceding a Diagnosis of Pancreatic Ductal Adenocarcinoma

Sah, R. P., Sharma, A., Nagpal, S., Patlolla, S. H., Sharma, A., Kandlakunta, H., Anani, V., Angom, R. S., Kamboj, A. K., Ahmed, N., Mohapatra, S., Vivekanandhan, S., Philbrick, K. A., Weston, A., Takahashi, N. M., Kirkland, J. L., Javeed, N., Matveyenko, A. V., Levy, M. J., Mukhopadhyay, D. & 1 others, Chari, S. T., May 1 2019, In : Gastroenterology. 156, 6, p. 1742-1752 11 p.

Research output: Contribution to journalArticle

Subcutaneous Fat
Adenocarcinoma
Intra-Abdominal Fat
Hyperglycemia
Abdominal Subcutaneous Fat

Physiology in Perspective: Of Mice and Men

Sieck, G. C., Jan 1 2019, In : Physiology (Bethesda, Md.). 34, 1, p. 3-4 2 p.

Research output: Contribution to journalArticle

Physiology in Perspective: Responding to a Changing Environment

Sieck, G. C., Mar 1 2019, In : Physiology (Bethesda, Md.). 34, 2, p. 84-85 2 p.

Research output: Contribution to journalArticle

Physiology in Perspective: The Dilemma of Muscle Weakness

Sieck, G. C., Jul 1 2019, In : Physiology (Bethesda, Md.). 34, 4, p. 230-231 2 p.

Research output: Contribution to journalArticle

Muscle Weakness

Physiology in Perspective: Physiology is Everywhere

Sieck, G. C., May 1 2019, In : Physiology (Bethesda, Md.). 34, 3, p. 167-168 2 p.

Research output: Contribution to journalArticle

Physiology in Perspective: Physiology Without Borders

Sieck, G. C., Sep 1 2019, In : Physiology (Bethesda, Md.). 34, 5, p. 300-301 2 p.

Research output: Contribution to journalArticle