Physiology & Biomedical Engineering

Research Output

2020

Accelerated osteocyte senescence and skeletal fragility in mice with type 2 diabetes

Eckhardt, B. A., Rowsey, J. L., Thicke, B. S., Fraser, D. G., O'Grady, K. L., Bondar, O. P., Hines, J. M., Singh, R. J., Thoreson, A. R., Rakshit, K., Lagnado, A. B., Passos, J. F., Vella, A., Matveyenko, A. V., Khosla, S., Monroe, D. G. & Farr, J. N., May 7 2020, In : JCI Insight. 5, 9, e135236.

Research output: Contribution to journalArticle

Open Access

A feasibility study fornoninvasive measurement of shear wave speed in live zebrafish

Zhang, X., Zhang, A. X., Zhou, B. & Xu, X., Sep 2020, In : Ultrasonics. 107, 106170.

Research output: Contribution to journalArticle

Aging reduces succinate dehydrogenase activity in rat type IIx/IIb diaphragm muscle fibers

Fogarty, M. J., Marin Mathieu, N., Mantilla, C. B. & Sieck, G. C., Jan 1 2020, In : Journal of applied physiology (Bethesda, Md. : 1985). 128, 1, p. 70-77 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Amelioration of age-related brain function decline by Bruton's tyrosine kinase inhibition

Ekpenyong-Akiba, A. E., Poblocka, M., Althubiti, M., Rada, M., Jurk, D., Germano, S., Kocsis-Fodor, G., Shi, Y., Canales, J. J. & Macip, S., Jan 1 2020, In : Aging Cell. 19, 1, e13079.

Research output: Contribution to journalArticle

Open Access

A method for the generation of human stem cell-derived alpha cells

Peterson, Q. P., Veres, A., Chen, L., Slama, M. Q., Kenty, J. H. R., Hassoun, S., Brown, M. R., Dou, H., Duffy, C. D., Zhou, Q., Matveyenko, A. V., Tyrberg, B., Sörhede-Winzell, M., Rorsman, P. & Melton, D. A., Dec 1 2020, In : Nature communications. 11, 1, 2241.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Automated sample preparation for nucleosome positioning analysis using droplet microfluidics

Xu, Y., Lee, J. H., Zhao, Y., Li, Z., Ordog, T. & Bailey, R. C., Jan 1 2020, 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017. Chemical and Biological Microsystems Society, p. 213-214 2 p. (21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Automated Segmentation of Thyroid Nodule, Gland, and Cystic Components from Ultrasound Images Using Deep Learning

Kumar, V., Webb, J., Gregory, A., Meixner, D. D., Knudsen, J. M., Callstrom, M., Fatemi, M. & Alizad, A., Jan 1 2020, In : IEEE Access. 8, p. 63482-63496 15 p., 9044381.

Research output: Contribution to journalArticle

Open Access

A Western diet impairs CNS energy homeostasis and recovery after spinal cord injury: Link to astrocyte metabolism

Kim, H. N., Langley, M. R., Simon, W. L., Yoon, H., Kleppe, L., Lanza, I. R., LeBrasseur, N. K., Matveyenko, A. & Scarisbrick, I. A., Jul 2020, In : Neurobiology of Disease. 141, 104934.

Research output: Contribution to journalArticle

Open Access

C-Elastography: In Vitro Feasibility Phantom Study

Shahraki, D. P., Kumar, V., Ghavami, S., Urban, M. W., Alizad, A., Guzina, B. B. & Fatemi, M., Jan 1 2020, (Accepted/In press) In : Ultrasound in Medicine and Biology.

Research output: Contribution to journalArticle

Cl- and H+ coupling properties and subcellular localizations of wildtype and disease-associated variants of the voltagegated Cl-/H+ exchanger ClC-5

Chang, M. D., Brown, M. R., Liu, Y., Gainullin, V. G., Harris, P. C., Romero, M. F. & Lieske, J. C., Jan 1 2020, In : Journal of Biological Chemistry. 295, 6, p. 1464-1473 10 p.

Research output: Contribution to journalArticle

Open Access

Combined spatiotemporal and frequency-dependent shear wave elastography enables detection of vulnerable carotid plaques as validated by MRI

Marlevi, D., Mulvagh, S. L., Huang, R., Kevin DeMarco, J., Ota, H., Huston, J., Winter, R., Macedo, T., Abdelmoneim, S. S., Larsson, M., Pellikka, P. A. & Urban, M. W., Dec 1 2020, In : Scientific reports. 10, 1, 403.

Research output: Contribution to journalArticle

Open Access

Comparing supraspinatus to acromion proximity and kinematics of the shoulder and thorax between manual wheelchair propulsion styles: A pilot study

Madansingh, S. I., Fortune, E., Morrow, M. M., Zhao, K. D. & Cloud-Biebl, B. A., Apr 2020, In : Clinical Biomechanics. 74, p. 42-50 9 p.

Research output: Contribution to journalArticle

Corrigendum to ‘Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease’ (EBioMedicine (2019) 47 (446–456), (S2352396419305912), (10.1016/j.ebiom.2019.08.069))

Hickson, L. T. J., Langhi Prata, L. G. P., Bobart, S. A., Evans, T. K., Giorgadze, N., Hashmi, S. K., Herrmann, S. M., Jensen, M. D., Jia, Q., Jordan, K. L., Kellogg, T. A., Khosla, S., Koerber, D. M., Lagnado, A. B., Lawson, D. K., LeBrasseur, N. K., Lerman, L. O., McDonald, K. M., McKenzie, T. J., Passos, J. F. & 18 others, Pignolo, R. J., Pirtskhalava, T., Saadiq, I. M., Schaefer, K. K., Textor, S. C., Victorelli, S. G., Volkman, T. L., Xue, A., Wentworth, M. A., Wissler Gerdes, E. O., Allison, D. B., Dickinson, S. L., Ejima, K., Atkinson, E. J., Lenburg, M., Zhu, Y., Tchkonia, T. & Kirkland, J. L., Feb 2020, In : EBioMedicine. 52, 102595.

Research output: Contribution to journalComment/debate

Open Access
3 Scopus citations

Current Evidence Lacking to Guide Clinical Practice for Spinal Cord Stimulation in the Treatment of Neuropathic Pain in Spinal Cord Injury: A Review of the Literature and a Proposal for Future Study

Dombovy-Johnson, M. L., Hunt, C. L., Morrow, M. M., Lamer, T. J. & Pittelkow, T. P., Mar 1 2020, In : Pain Practice. 20, 3, p. 325-335 11 p.

Research output: Contribution to journalReview article

1 Scopus citations

Diaphragm muscle sarcopenia into very old age in mice

Vang, P., Vasdev, A., Zhan, W. Z., Gransee, H. M., Sieck, G. C. & Mantilla, C. B., Jan 1 2020, In : Physiological reports. 8, 1, e14305.

Research output: Contribution to journalArticle

Open Access

Dietary carbohydrates modulate metabolic and β-cell adaptation to high-fat diet-induced obesity

Her, T. K., Lagakos, W. S., Brown, M. R., LeBrasseur, N. K., Rakshit, K. & Matveyenko, A. V., May 20 2020, In : American Journal of Physiology - Endocrinology and Metabolism. 318, 6, p. E856-E865

Research output: Contribution to journalArticle

Open Access

Dose reduction in molecular breast imaging with a new image-processing algorithm

Tao, A. T., Hruska, C. B., Conners, A. L., Hunt, K. N., Swanson, T. N., Tran, T. D., Manduca, A., Borges, L., Maidment, A. D. A., Lake, D., Johnson, M. P., Carter, R. E., Rhodes, D. J. & O'Connor, M. K., Jan 1 2020, In : American Journal of Roentgenology. 214, 1, p. 185-193 9 p.

Research output: Contribution to journalArticle

Endoplasmic Reticulum Stress and Mitochondrial Function in Airway Smooth Muscle

Delmotte, P. & Sieck, G. C., Jan 15 2020, In : Frontiers in Cell and Developmental Biology. 7, 374.

Research output: Contribution to journalReview article

Open Access

Epigenetic Alterations Are Associated With Gastric Emptying Disturbances in Diabetes Mellitus

Puthanmadhom Narayanan, S., Lee, J. H., Bhagwate, A., Kuwelker, S., Yan, H. D., Ordog, T. & Bharucha, A. E., Mar 1 2020, In : Clinical and translational gastroenterology. 11, 3, p. e00136

Research output: Contribution to journalArticle

Open Access

Fibrodysplasia Ossificans Progressiva (FOP): A Segmental Progeroid Syndrome

Pignolo, R. J., Wang, H. & Kaplan, F. S., Jan 10 2020, In : Frontiers in Endocrinology. 10, 908.

Research output: Contribution to journalReview article

Open Access
2 Scopus citations

Gap-Filling Method for Suppressing Grating Lobes in Ultrasound Imaging: Experimental Study with Deep-Learning Approach

Kumar, V., Lee, P. Y., Kim, B. H., Fatemi, M. & Alizad, A., Jan 1 2020, In : IEEE Access. 8, p. 76276-76286 11 p., 9075177.

Research output: Contribution to journalArticle

Open Access

Heterogeneous glutamatergic receptor mRNA expression across phrenic motor neurons in rats

Rana, S., Sieck, G. C. & Mantilla, C. B., Jun 1 2020, In : Journal of neurochemistry. 153, 5, p. 586-598 13 p.

Research output: Contribution to journalArticle

1 Scopus citations

Heterotopic ossification of tendon and ligament

Zhang, Q., Zhou, D., Wang, H. & Tan, J., May 1 2020, In : Journal of Cellular and Molecular Medicine. 24, 10, p. 5428-5437 10 p.

Research output: Contribution to journalReview article

Open Access
3 Scopus citations

High-fat diet–induced alterations to gut microbiota and gut-derived lipoteichoic acid contributes to the development of enteric neuropathy

Nyavor, Y., Brands, C. R., May, G., Kuther, S., Nicholson, J., Tiger, K., Tesnohlidek, A., Yasuda, A., Starks, K., Litvinenko, D., Linden, D. R., Bhattarai, Y., Kashyap, P. C., Forney, L. J. & Balemba, O. B., Jul 1 2020, In : Neurogastroenterology and Motility. 32, 7, e13838.

Research output: Contribution to journalArticle

Open Access

Identification of Normal Pressure Hydrocephalus by Disease-Specific Patterns of Brain Stiffness and Damping Ratio

Murphy, M. C., Cogswell, P. M., Trzasko, J. D., Manduca, A., Senjem, M. L., Meyer, F., Ehman, R. L. & Huston, J., Apr 1 2020, In : Investigative radiology. 55, 4, p. 200-208 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Identification of osteoclast-osteoblast coupling factors in humans reveals links between bone and energy metabolism

Weivoda, M. M., Chew, C. K., Monroe, D. G., Farr, J. N., Atkinson, E. J., Geske, J. R., Eckhardt, B., Thicke, B., Ruan, M., Tweed, A. J., McCready, L. K., Rizza, R. A., Matveyenko, A., Kassem, M., Andersen, T. L., Vella, A., Drake, M. T., Clarke, B. L., Oursler, M. J. & Khosla, S., Dec 1 2020, In : Nature communications. 11, 1, 87.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Impact of imaging cross-section on visualization of thyroid microvessels using ultrasound: Pilot study

Nayak, R., Nawar, N., Webb, J., Fatemi, M. & Alizad, A., Dec 1 2020, In : Scientific reports. 10, 1, 415.

Research output: Contribution to journalArticle

Open Access

Impact of Procedure Type, Case Duration, and Adjunctive Equipment on Surgeon Intraoperative Musculoskeletal Discomfort

Yang, L., Money, S. R., Morrow, M. M., Lowndes, B. R., Weidner, T. K., Fortune, E., Davila, V. J., Meltzer, A. J., Stone, W. M. & Hallbeck, M. S., Apr 2020, In : Journal of the American College of Surgeons. 230, 4, p. 554-560 7 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Impaired neuromuscular transmission of the tibialis anterior in a rodent model of hypertonia

Fogarty, M. J., Sieck, G. C. & Brandenburg, J. E., May 2020, In : Journal of neurophysiology. 123, 5, p. 1869-2020 152 p.

Research output: Contribution to journalArticle

Open Access

Inferring multimodal latent topics from electronic health records

Li, Y., Nair, P., Lu, X. H., Wen, Z., Wang, Y., Dehaghi, A. A. K., Miao, Y., Liu, W., Ordog, T., Biernacka, J. M., Ryu, E., Olson, J. E., Frye, M. A., Liu, A., Guo, L., Marelli, A., Ahuja, Y., Davila-Velderrain, J. & Kellis, M., Dec 1 2020, In : Nature communications. 11, 1, 2536.

Research output: Contribution to journalArticle

Open Access

Inhibition of TrkB kinase activity impairs transdiaphragmatic pressure generation

Pareja-Cajiao, M., Gransee, H. M., Cole, N. A., Sieck, G. C. & Mantilla, C. B., Jan 1 2020, In : Journal of applied physiology. 128, 2, p. 338-344 7 p.

Research output: Contribution to journalArticle

In vitro Remote Aspiration Embolectomy for the Treatment of Acute Ischemic Stroke

Rizvi, A., Fitzgerald, S. T., Carlson, K. D., Daescu, D. D., Brinjikji, W., Kadirvel, R. & Kallmes, D. F., Feb 1 2020, In : Interventional Neurology. 8, 1, p. 20-26 7 p.

Research output: Contribution to journalArticle

It's about time: Clocks in the developing lung

Bartman, C. M., Matveyenko, A. & Prakash, Y. S., Jan 2 2020, In : Journal of Clinical Investigation. 130, 1, p. 39-50 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

Measuring ergonomic risk in operating surgeons by using wearable technology

Meltzer, A. J., Hallbeck, M. S., Morrow, M. M., Lowndes, B. R., Davila, V. J., Stone, W. M. & Money, S. R., May 2020, In : JAMA surgery. 155, 5, p. 444-446 3 p.

Research output: Contribution to journalLetter

Open Access
1 Scopus citations

Mechano-therapeutics: Targeting Mechanical Signaling in Fibrosis and Tumor Stroma

Tschumperlin, D. J. & Lagares, D., Aug 2020, In : Pharmacology and Therapeutics. 212, 107575.

Research output: Contribution to journalReview article

Microfluidic devices, accumulation of endogenous signals and stem cell fate selection

Fattahi, P., Haque, A., Son, K. J., Guild, J. & Revzin, A., Mar 1 2020, In : Differentiation. 112, p. 39-46 8 p.

Research output: Contribution to journalReview article

MicroRNA overexpression in slow transit constipation leads to reduced Na v 1.5 current and altered smooth muscle contractility

Mazzone, A., Strege, P. R., Gibbons, S. J., Alcaino, C., Joshi, V., Haak, A. J., Tschumperlin, D. J., Bernard, C. E., Cima, R. R., Larson, D. W., Chua, H. K., Graham, R. P., El Refaey, M., Mohler, P. J., Hayashi, Y., Ordog, T., Calder, S., Du, P., Farrugia, G. & Beyder, A., May 1 2020, In : Gut. 69, 5, p. 868-876 9 p.

Research output: Contribution to journalArticle

Open Access

Mitochondria-to-nucleus retrograde signaling drives formation of cytoplasmic chromatin and inflammation in senescence

Vizioli, M. G., Liu, T., Miller, K. N., Robertson, N. A., Gilroy, K., Lagnado, A. B., Perez-Garcia, A., Kiourtis, C., Dasgupta, N., Lei, X., Kruger, P. J., Nixon, C., Clark, W., Jurk, D., Bird, T. G., Passos, J. F., Berger, S. L., Dou, Z. & Adams, P. D., Mar 1 2020, In : Genes and Development. 34, 5, p. 428-445 18 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

NBCe1-A is required for the renal ammonia and K+ response to hypokalemia

Lee, H. W., Harris, A. N., Romero, M. F., Welling, P. A., Wingo, C. S., Verlander, J. W. & Weiner, I. D., Feb 1 2020, In : American journal of physiology. Renal physiology. 318, 2, p. F402-F421

Research output: Contribution to journalArticle

1 Scopus citations

Optical coherence tomography for evaluating capillary waves in blood and plasma

Liu, H. C., Kijanka, P. & Urban, M. W., Feb 1 2020, In : Biomedical Optics Express. 11, 2, p. 1092-1106 15 p.

Research output: Contribution to journalArticle

Patient specific characterization of artery and plaque material properties in peripheral artery disease

Noble, C., Carlson, K. D., Neumann, E., Dragomir-Daescu, D., Erdemir, A., Lerman, A. & Young, M., Jan 2020, In : Journal of the Mechanical Behavior of Biomedical Materials. 101, 103453.

Research output: Contribution to journalArticle

Open Access

Phrenic motor neuron loss in an animal model of early onset hypertonia

Brandenburg, J. E., Fogarty, M. J., Brown, A. D. & Sieck, G. C., May 2020, In : Journal of neurophysiology. 123, 5, p. 1682-1690 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Physiology in perspective: In a world of social distancing

Sieck, G. C., May 2020, In : Physiology. 35, 3, p. 158-159 2 p.

Research output: Contribution to journalEditorial

Open Access

Physiology in perspective: Physiological systems respond to time

Sieck, G. C., Jan 1 2020, In : Physiology. 35, 2, p. 84-85 2 p.

Research output: Contribution to journalComment/debate

Open Access

Physiology in perspective: The new normal—life in a pandemic

Sieck, G. C., Jul 2020, In : Physiology. 35, 4, p. 220-221 2 p.

Research output: Contribution to journalComment/debate

Open Access