Research Output

2016

Neuropathologic differences by race from the National Alzheimer's Coordinating Center

Graff-Radford, N. R., Besser, L. M., Crook, J. E., Kukull, W. A. & Dickson, D. W., Jun 1 2016, In : Alzheimer's and Dementia. 12, 6, p. 669-677 9 p.

Research output: Contribution to journalArticle

30 Scopus citations

Opposing roles of the triggering receptor expressed on myeloid cells 2 and triggering receptor expressed on myeloid cells-like transcript 2 in microglia activation

Zheng, H., Liu, C. C., Atagi, Y., Chen, X. F., Jia, L., Yang, L., He, W., Zhang, X., Kang, S. S., Rosenberry, T. L., Fryer, J. D., Zhang, Y. W., Xu, H. & Bu, G., Jun 1 2016, In : Neurobiology of aging. 42, p. 132-141 10 p.

Research output: Contribution to journalArticle

34 Scopus citations

Patterns of etiology and antibiotic resistance of bacteria causing urinary tract infections in the Anhui Provincial Hospital

Ren, W., Fang, Y., Chen, W., Dickson, D. W., Pan, H. X., Wang, P., Lan, L. & Ni, L. J., Feb 29 2016, In : International Journal of Clinical and Experimental Medicine. 9, 2, p. 4515-4520 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Pioglitazone prevents tau oligomerization

Hamano, T., Shirafuji, N., Makino, C., Yen, S. H., Kanaan, N. M., Ueno, A., Suzuki, J., Ikawa, M., Matsunaga, A., Yamamura, O., Kuriyama, M. & Nakamoto, Y., 2016, In : Biochemical and Biophysical Research Communications. 478, 3, p. 1035-1042 8 p.

Research output: Contribution to journalArticle

12 Scopus citations
18 Scopus citations

Poly(GR) in C9ORF72-Related ALS/FTD Compromises Mitochondrial Function and Increases Oxidative Stress and DNA Damage in iPSC-Derived Motor Neurons

Lopez-Gonzalez, R., Lu, Y., Gendron, T. F., Karydas, A., Tran, H., Yang, D., Petrucelli, L., Miller, B. L., Almeida, S. & Gao, F. B., Oct 19 2016, In : Neuron. 92, 2, p. 383-391 9 p.

Research output: Contribution to journalArticle

117 Scopus citations

Predicting Survival in Dementia With Lewy Bodies With Hippocampal Volumetry

Graff-Radford, J., Lesnick, T. G., Boeve, B. F., Przybelski, S. A., Jones, D. T., Senjem, M. L., Gunter, J. L., Ferman, T. J., Knopman, D. S., Murray, M. E., Dickson, D. W., Sarro, L., Jack, C. R., Petersen, R. C. & Kantarci, K., Jul 1 2016, In : Movement Disorders. 31, 7, p. 989-994 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

Primary familial brain calcification in the ‘IBGC2’ kindred: All linkage roads lead to SLC20A2

Grütz, K., Volpato, C. B., Domingo, A., Alvarez-Fischer, D., Gebert, U., Schifferle, G., Buffone, E., Wszolek, Z. K., Rademakers, R., Ferbert, A., Hicks, A. A., Klein, C., Pramstaller, P. P. & Westenberger, A., Dec 1 2016, In : Movement Disorders. 31, 12, p. 1901-1904 4 p.

Research output: Contribution to journalArticle

14 Scopus citations

Proaggregant nuclear factor(s) trigger rapid formation of α-synuclein aggregates in apoptotic neurons

Jiang, P., Gan, M., Yen, S. H., Moussaud, S., McLean, P. J. & Dickson, D. W., Jul 1 2016, In : Acta neuropathologica. 132, 1, p. 77-91 15 p.

Research output: Contribution to journalArticle

11 Scopus citations

Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation

Lui, H., Zhang, J., Makinson, S. R., Cahill, M. K., Kelley, K. W., Huang, H. Y., Shang, Y., Oldham, M. C., Martens, L. H., Gao, F., Coppola, G., Sloan, S. A., Hsieh, C. L., Kim, C. C., Bigio, E. H., Weintraub, S., Mesulam, M. M., Rademakers, R., MacKenzie, I. R., Seeley, W. W. & 8 others, Karydas, A., Miller, B. L., Borroni, B., Ghidoni, R., Farese, R. V., Paz, J. T., Barres, B. A. & Huang, E. J., May 5 2016, In : Cell. 165, 4, p. 921-935 15 p.

Research output: Contribution to journalArticle

232 Scopus citations

Propagation of tau pathology: hypotheses, discoveries, and yet unresolved questions from experimental and human brain studies

Lewis, J. & Dickson, D. W., Jan 1 2016, In : Acta neuropathologica. 131, 1, p. 27-48 22 p.

Research output: Contribution to journalReview article

81 Scopus citations

Prosaposin is a regulator of progranulin levels and oligomerization

Nicholson, A. M., Finch, N. C. A., Almeida, M., Perkerson, R. B., Van Blitterswijk, M., Wojtas, A., Cenik, B., Rotondo, S., Inskeep, V., Almasy, L., Dyer, T., Peralta, J., Jun, G., Wood, A. R., Frayling, T. M., Fuchsberger, C., Fowler, S., Teslovich, T. M., Manning, A. K., Kumar, S. & 20 others, Curran, J., Lehman, D., Abecasis, G., Duggirala, R., Pottier, C., Zahir, H. A., Crook, J. E., Karydas, A., Mitic, L., Sun, Y., Dickson, D. W., Bu, G., Herz, J., Yu, G., Miller, B. L., Ferguson, S., Petersen, R. C., Graff-Radford, N., Blangero, J. & Rademakers, R., Jun 30 2016, In : Nature communications. 7, 11992.

Research output: Contribution to journalArticle

28 Scopus citations

Quantitative characterization of brain β-amyloid in 718 normal subjects using a joint PiB/FDG PET image histogram

Camp, J. J., Hanson, D. P., Lowe, V., Kemp, B. J., Senjem, M. L., Murray, M. E., Dickson, D. W., Parisi, J. E., Petersen, R. C., Robb, R. A. & Holmes III, D. R., 2016, Medical Imaging 2016: Computer-Aided Diagnosis. SPIE, Vol. 9785. 97852V

Research output: Chapter in Book/Report/Conference proceedingConference contribution

RAB39B gene mutations are not a common cause of Parkinson's disease or dementia with Lewy bodies

Hodges, K., Brewer, S. S., Labbé, C., Soto-Ortolaza, A. I., Walton, R. L., Strongosky, A. J., Uitti, R. J., van Gerpen, J. A., Ertekin-Taner, N., Kantarci, K., Lowe, V. J., Parisi, J. E., Savica, R., Graff-Radford, J., Jones, D. T., Knopman, D. S., Petersen, R. C., Murray, M. E., Graff-Radford, N. R., Ferman, T. J. & 5 others, Dickson, D. W., Wszolek, Z. K., Boeve, B. F., Ross, O. A. & Lorenzo-Betancor, O., Sep 1 2016, In : Neurobiology of aging. 45, p. 107-108 2 p.

Research output: Contribution to journalArticle

13 Scopus citations

Rapid in vivo measurement of ß-amyloid reveals biphasic clearance kinetics in an Alzheimer's mouse model

Yuede, C. M., Lee, H., Restivo, J. L., Davis, T. A., Hettinger, J. C., Wallace, C. E., Young, K. L., Hayne, M. R., Bu, G., Li, C. Z. & Cirrito, J. R., May 2 2016, In : Journal of Experimental Medicine. 213, 5, p. 677-685 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Rare variants in MC1R/TUBB3 exon 1 are not associated with Parkinson's disease

Lorenzo-Betancor, O., Wszolek, Z. K. & Ross, O. A., Feb 1 2016, In : Annals of neurology. 79, 2, p. 331 1 p.

Research output: Contribution to journalLetter

4 Scopus citations

Rescuing effects of RXR agonist bexarotene on aging-related synapse loss depend on neuronal LRP1

Tachibana, M., Shinohara, M., Yamazaki, Y., Liu, C. C., Rogers, J., Bu, G. & Kanekiyo, T., Mar 1 2016, In : Experimental Neurology. 277, p. 1-9 9 p.

Research output: Contribution to journalArticle

32 Scopus citations

Shared genetic contribution to ischemic stroke and Alzheimer's disease

Traylor, M., Adib-Samii, P., Harold, D., Dichgans, M., Williams, J., Lewis, C. M., Markus, H. S., Fornage, M., Holliday, E. G., Sharma, P., Bis, J. C., Psaty, B. M., Seshadri, S., Nalls, M. A., Devan, W. J., Boncoraglio, G., Malik, R., Mitchell, B. D., Kittner, S. J., Ikram, M. A. & 188 others, Clarke, R., Rosand, J., Meschia, J. F., Sudlow, C., Rothwell, P. M., Levi, C., Bevan, S., Kilarski, L. L., Walters, M., Thijs, V., Slowik, A., Lindgren, A., De Bakker, P. I. W., Lambert, J. C., Ibrahim-Verbaas, C. A., Naj, A. C., Sims, R., Bellenguez, C., Jun, G., Destefano, A. L., Beecham, G. W., Grenier-Boley, B., Russo, G., Thornton-Wells, T. A., Jones, N., Smith, A. V., Chouraki, V., Thomas, C., Zelenika, D., Vardarajan, B. N., Kamatani, Y., Lin, C. F., Gerrish, A., Schmidt, H., Kunkle, B., Dunstan, M. L., Ruiz, A., Bihoreau, M. T., Choi, S. H., Reitz, C., Pasquier, F., Hollingworth, P., Ramirez, A., Hanon, O., Fitzpatrick, A. L., Buxbaum, J. D., Campion, D., Crane, P. K., Baldwin, C., Becker, T., Gudnason, V., Cruchaga, C., Craig, D., Amin, N., Berr, C., Lopez, O. L., De Jager, P. L., Deramecourt, V., Johnston, J. A., Evans, D., Lovestone, S., Letenneur, L., Morón, F. J., Rubinsztein, D. C., Eiriksdottir, G., Sleegers, K., Goate, A. M., Fiçvet, N., Huentelman, M. J., Gill, M., Brown, K., Kamboh, M. I., Keller, L., Barberger-Gateau, P., McGuinness, B., Larson, E. B., Green, R., Myers, A. J., Dufouil, C., Todd, S., Wallon, D., Love, S., Rogaeva, E., Gallacher, J., St George-Hyslop, P., Clarimon, J., Lleo, A., Bayer, A., Tsuang, D. W., Yu, L., Tsolaki, M., Bossù, P., Spalletta, G., Proitsi, P., Collinge, J., Sorbi, S., Sanchez-Garcia, F., Fox, N. C., Hardy, J., Deniz Naranjo, M. C., Bosco, P., Brayne, C., Galimberti, D., Mancuso, M., Matthews, F., Moebus, S., Mecocci, P., Del Zompo, M., Maier, W., Hampel, H., Pilotto, A., Bullido, M., Panza, F., Caffarra, P., Nacmias, B., Gilbert, J. R., Mayhaus, M., Lannfelt, L., Hakonarson, H., Pichler, S., Carrasquillo, M. M., Ingelsson, M., Beekly, D., Alvarez, V., Zou, F., Valladares, O., Younkin, S. G., Coto, E., Hamilton-Nelson, K. L., Gu, W., Razquin, C., Pastor, P., Mateo, I., Owen, M. J., Faber, K. M., Jonsson, P. V., Combarros, O., O'Donovan, M. C., Cantwell, L. B., Soininen, H., Blacker, D., Mead, S., Mosley, T. H., Bennett, D. A., Harris, T. B., Fratiglioni, L., Holmes, C., De Bruijn, R. F. A. G., Passmore, P., Montine, T. J., Bettens, K., Rotter, J. I., Brice, A., Morgan, K., Foroud, T. M., Kukull, W. A., Hannequin, D., Powell, J. F., Nalls, M. A., Ritchie, K., Lunetta, K. L., Kauwe, J. S. K., Boerwinkle, E., Riemenschneider, M., Boada, M., Hiltunen, M., Martin, E. R., Schmidt, R., Rujescu, D., Wang, L. S., Dartigues, J. F., Mayeux, R., Tzourio, C., Hofman, A., Nöthen, M. M., Graff, C., Jones, L., Haines, J. L., Holmans, P. A., Lathrop, M., Pericak-Vance, M. A., Launer, L. J., Farrer, L. A., Van Duijn, C. M., Van Broeckhoven, C., Moskvina, V., Schellenberg, G. D. & Amouyel, P., May 1 2016, In : Annals of neurology. 79, 5, p. 739-747 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

SNX15 Regulates Cell Surface Recycling of APP and Aβ Generation

Feng, T., Niu, M., Ji, C., Gao, Y., Wen, J., Bu, G., Xu, H. & Zhang, Y. W., Aug 1 2016, In : Molecular Neurobiology. 53, 6, p. 3690-3701 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

SNX27 deletion causes hydrocephalus by impairing ependymal cell differentiation and ciliogenesis

Wang, X., Zhou, Y., Wang, J., Tseng, I. C., Huang, T., Zhao, Y., Zheng, Q., Gao, Y., Luo, H., Zhang, X., Bu, G., Hong, W. & Xu, H., Dec 14 2016, In : Journal of Neuroscience. 36, 50, p. 12586-12597 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Soluble sortilin is present in excess and positively correlates with progranulin in CSF of aging individuals

Molgaard, S., Demontis, D., Nicholson, A. M., Finch, N. A., Petersen, R. C., Petersen, C. M., Rademakers, R. V., Nykjaer, A. & Glerup, S., Nov 1 2016, In : Experimental Gerontology. 84, p. 96-100 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Spt4 selectively regulates the expression of C9orf72 sense and antisense mutant transcripts

Kramer, N. J., Carlomagno, Y., Zhang, Y. J., Almeida, S., Cook, C. N., Gendron, T. F., Prudencio, M., Van Blitterswijk, M., Belzil, V., Couthouis, J., Paul, J. W., Goodman, L. D., Daughrity, L., Chew, J., Garrett, A., Pregent, L., Jansen-West, K., Tabassian, L. J., Rademakers, R., Boylan, K. & 16 others, Graff-Radford, N. R., Josephs, K. A., Parisi, J. E., Knopman, D. S., Petersen, R. C., Boeve, B. F., Deng, N., Feng, Y., Cheng, T. H., Dickson, D. W., Cohen, S. N., Bonini, N. M., Link, C. D., Gao, F. B., Petrucelli, L. & Gitler, A. D., Aug 12 2016, In : Science. 353, 6300, p. 708-712 5 p.

Research output: Contribution to journalArticle

56 Scopus citations

Suspected non-Alzheimer disease pathophysiology-concept and controversy

Jack, C. R., Knopman, D. S., Chételat, G., Dickson, D., Fagan, A. M., Frisoni, G. B., Jagust, W., Mormino, E. C., Petersen, R. C., Sperling, R. A., Van Der Flier, W. M., Villemagne, V. L., Visser, P. J. & Vos, S. J. B., Feb 1 2016, In : Nature Reviews Neurology. 12, 2, p. 117-124 8 p.

Research output: Contribution to journalReview article

139 Scopus citations

TDP-43 functions within a network of hnRNP proteins to inhibit the production of a truncated human SORT1 receptor

Mohagheghi, F., Prudencio, M., Stuani, C., Cook, C., Jansen-West, K., Dickson, D. W., Petrucelli, L. & Buratti, E., Feb 1 2016, In : Human molecular genetics. 25, 3, p. 534-545 12 p.

Research output: Contribution to journalArticle

34 Scopus citations

TDP-43 in the olfactory bulb in Alzheimer's disease

Josephs, K. A. & Dickson, D. W., Jun 1 2016, In : Neuropathology and Applied Neurobiology. 42, 4, p. 390-393 4 p.

Research output: Contribution to journalLetter

4 Scopus citations

The extreme N-terminus of TDP-43 mediates the cytoplasmic aggregation of TDP-43 and associated toxicity in vivo

Sasaguri, H., Chew, J., Xu, Y. F., Gendron, T. F., Garrett, A., Lee, C. W., Jansen-West, K., Bauer, P. O., Perkerson, E. A., Tong, J., Stetler, C. & Zhang, Y. J., Sep 15 2016, In : Brain Research. 1647, p. 57-64 8 p.

Research output: Contribution to journalReview article

19 Scopus citations

The first NINDS/NIBIB consensus meeting to define neuropathological criteria for the diagnosis of chronic traumatic encephalopathy

McKee, A. C., Cairns, N. J., Dickson, D. W., Folkerth, R. D., Dirk Keene, C., Litvan, I., Perl, D. P., Stein, T. D., Vonsattel, J. P., Stewart, W., Tripodis, Y., Crary, J. F., Bieniek, K. F., Dams-O’Connor, K., Alvarez, V. E. & Gordon, W. A., Jan 1 2016, In : Acta neuropathologica. 131, 1, p. 75-86 12 p.

Research output: Contribution to journalArticle

367 Scopus citations

The neural chaperone proSAAS blocks α-synuclein fibrillation and neurotoxicity

Jarvela, T. S., Lam, H. A., Helwig, M., Lorenzen, N., Otzen, D. E., McLean, P. J., Maidment, N. T. & Lindberg, I., Aug 9 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 32, p. E4708-E4715

Research output: Contribution to journalArticle

13 Scopus citations

The presenilin 1 p.Gly206Ala mutation is a frequent cause of early-onset alzheimer’s disease in Hispanics in Florida

Ravenscroft, T. A., Pottier, C., Murray, M. E., Baker, M., Christopher, E., Levitch, D., Brown, P. H., Barker, W., Duara, R., Greig-Custo, M., Betancourt, A., English, M., Sun, X., Taner, N., Graff Radford, N. R., Dickson, D. W. & Rademakers, R. V., 2016, In : American Journal of Neurodegenerative Diseases. 5, 1, p. 94-101 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

The role of APOE in cerebrovascular dysfunction

Tai, L. M., Thomas, R., Marottoli, F. M., Koster, K. P., Kanekiyo, T., Morris, A. W. J. & Bu, G., May 1 2016, In : Acta neuropathologica. 131, 5, p. 709-723 15 p.

Research output: Contribution to journalReview article

61 Scopus citations

Timing and significance of pathological features in C9orf72 expansion-associated frontotemporal dementia

Vatsavayai, S. C., Yoon, S. J., Gardner, R. C., Gendron, T. F., Vargas, J. N. S., Trujillo, A., Pribadi, M., Phillips, J. J., Gaus, S. E., Hixson, J. D., Garcia, P. A., Rabinovici, G. D., Coppola, G., Geschwind, D. H., Petrucelli, L., Miller, B. L. & Seeley, W. W., 2016, In : Brain. 139, 12, p. 3202-3216 15 p.

Research output: Contribution to journalArticle

52 Scopus citations

Tissue Transglutaminase and Its Product Isopeptide Are Increased in Alzheimer’s Disease and APPswe/PS1dE9 Double Transgenic Mice Brains

Zhang, J., Wang, S., Huang, W., Bennett, D. A., Dickson, D. W., Wang, D. & Wang, R., Oct 1 2016, In : Molecular Neurobiology. 53, 8, p. 5066-5078 13 p.

Research output: Contribution to journalArticle

12 Scopus citations

Trehalose upregulates progranulin expression in human and mouse models of GRN haploinsufficiency: A novel therapeutic lead to treat frontotemporal dementia

Holler, C. J., Taylor, G., McEachin, Z. T., Deng, Q., Watkins, W. J., Hudson, K., Easley, C. A., Hu, W. T., Hales, C. M., Rossoll, W., Bassell, G. J. & Kukar, T., Jun 24 2016, In : Molecular neurodegeneration. 11, 1, 46.

Research output: Contribution to journalArticle

40 Scopus citations

TREM2 p.R47H substitution is not associated with dementia with Lewy bodies

Walton, R. L., Soto-Ortolaza, A. I., Murray, M. E., Lorenzo-Betancor, O., Ogaki, K., Heckman, M. G., Rayaprolu, S., Rademakers, R., Ertekin-Taner, N., Uitti, R. J., Van Gerpen, J. A., Wszolek, Z. K., Smith, G. E., Kantarci, K., Lowe, V. J., Parisi, J. E., Jones, D. T., Savica, R., Graff-Radford, J., Knopman, D. S. & 7 others, Petersen, R. C., Graff-Radford, N. R., Ferman, T. J., Dickson, D. W., Boeve, B. F., Ross, O. A. & Labbé, C., Aug 1 2016, In : Neurology: Genetics. 2, 4, e85.

Research output: Contribution to journalComment/debate

10 Scopus citations

Tremor in progressive supranuclear palsy

Fujioka, S., Algom, A. A., Murray, M. E., Sanchez-Contreras, M. Y., Tacik, P., Tsuboi, Y., Van Gerpen, J. A., Uitti, R. J., Rademakers, R., Ross, O. A., Wszolek, Z. K. & Dickson, D. W., 2016, In : Parkinsonism and Related Disorders. 27, p. 93-97 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

TREMs in Alzheimer's disease: Genetic and clinical investigations

Cheng, J., Guo, X. F., Zhang, T., Zhong, L., Bu, G. D. & Chen, X. F., Dec 1 2016, In : Clinica Chimica Acta. 463, p. 88-95 8 p.

Research output: Contribution to journalReview article

11 Scopus citations

TYROBP genetic variants in early-onset Alzheimer's disease

Pottier, C., Ravenscroft, T. A., Brown, P. H., Finch, N. C. A., Baker, M., Parsons, M., Asmann, Y. W., Ren, Y., Christopher, E., Levitch, D., van Blitterswijk, M., Cruchaga, C., Campion, D., Nicolas, G., Richard, A. C., Guerreiro, R., Bras, J. T., Zuchner, S., Gonzalez, M. A., Bu, G. & 10 others, Younkin, S., Knopman, D. S., Josephs, K. A., Parisi, J. E., Petersen, R. C., Ertekin-Taner, N., Graff-Radford, N. R., Boeve, B. F., Dickson, D. W. & Rademakers, R., Dec 1 2016, In : Neurobiology of aging. 48, p. 222.e9-222.e15

Research output: Contribution to journalArticle

31 Scopus citations

Updated TDP-43 in Alzheimer’s disease staging scheme

Josephs, K. A., Murray, M. E., Whitwell, J. L., Tosakulwong, N., Weigand, S. D., Petrucelli, L., Liesinger, A. M., Petersen, R. C., Parisi, J. E. & Dickson, D. W., Apr 1 2016, In : Acta neuropathologica. 131, 4, p. 571-585 15 p.

Research output: Contribution to journalArticle

105 Scopus citations

Vascular cell senescence contributes to blood-brain barrier breakdown

Yamazaki, Y., Baker, D. J., Tachibana, M., Liu, C. C., Van Deursen, J. M., Brott, T. G., Bu, G. & Kanekiyo, T., 2016, In : Stroke. 47, 4, p. 1068-1077 10 p.

Research output: Contribution to journalArticle

49 Scopus citations

VPS35 regulates cell surface recycling and signaling of dopamine receptor D1

Wang, C., Niu, M., Zhou, Z., Zheng, X., Zhang, L., Tian, Y., Yu, X., Bu, G., Xu, H., Ma, Q. & Zhang, Y. W., Oct 1 2016, In : Neurobiology of aging. 46, p. 22-31 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

What we know about TMEM106B in neurodegeneration

Nicholson, A. M. & Rademakers, R., Nov 1 2016, In : Acta neuropathologica. 132, 5, p. 639-651 13 p.

Research output: Contribution to journalReview article

39 Scopus citations

α-synuclein genetic variability: A biomarker for dementia in Parkinson disease

Guella, I., Evans, D. M., Szu-Tu, C., Nosova, E., Bortnick, S. F., Goldman, J. G., Dalrymple-Alford, J. C., Geurtsen, G. J., Litvan, I., Ross, O. A., Middleton, L. T., Parkkinen, L. & Farrer, M. J., Jun 1 2016, In : Annals of neurology. 79, 6, p. 991-999 9 p.

Research output: Contribution to journalArticle

52 Scopus citations
2015

(Patho-)physiological relevance of PINK1-dependent ubiquitin phosphorylation

Fiesel, F. C., Ando, M., Hudec, R., Hill, A. R., Castanedes-Casey, M., Caulfield, T. R., Moussaud-Lamodière, E. L., Stankowski, J. N., Bauer, P. O., Lorenzo-Betancor, O., Ferrer, I., Arbelo, J. M., Siuda, J., Chen, L., Dawson, V. L., Dawson, T. M., Wszolek, Z. K., Ross, O. A., Dickson, D. W. & Springer, W., Sep 1 2015, In : EMBO Reports. 16, 9, p. 1114-1130 17 p.

Research output: Contribution to journalArticle

65 Scopus citations

A commentary on fine mapping and resequencing of the PARK16 locus in Parkinson's disease

Trinh, J., Vilarino-Guell, C. & Ross, O. A., Aug 26 2015, In : Journal of Human Genetics. 60, 8, p. 405-406 2 p.

Research output: Contribution to journalArticle

1 Scopus citations

Activation of the E3 ubiquitin ligase Parkin

Caulfield, T. R., Fiesel, F. C. & Springer, W., Apr 1 2015, In : Biochemical Society Transactions. 43, p. 269-274 6 p.

Research output: Contribution to journalArticle

26 Scopus citations

Age and Its Association with Low Insulin and High Amyloid-β Peptides in Blood

Li, H., Zhu, H., Wallack, M., Mwamburi, M., Abdul-Hay, S. O., Leissring, M. A. & Qiu, W. Q., 2015, In : Journal of Alzheimer's Disease. 49, 1, p. 129-137 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function

Murakami, T., Qamar, S., Lin, J. Q., Schierle, G. S. K., Rees, E., Miyashita, A., Costa, A. R., Dodd, R. B., Chan, F. T. S., Michel, C. H., Kronenberg-Versteeg, D., Li, Y., Yang, S. P., Wakutani, Y., Meadows, W., Ferry, R. R., Dong, L., Tartaglia, G. G., Favrin, G., Lin, W. L. & 10 others, Dickson, D. W., Zhen, M., Ron, D., Schmitt-Ulms, G., Fraser, P. E., Shneider, N. A., Holt, C., Vendruscolo, M., Kaminski, C. F. & St George-Hyslop, P., Nov 18 2015, In : Neuron. 88, 4, p. 678-690 13 p.

Research output: Contribution to journalArticle

285 Scopus citations

Altered innate immune and glial cell responses to inflammatory stimuli in amyloid precursor protein knockout mice

Carrano, A. & Das, P., Oct 8 2015, In : PloS one. 10, 10, e0140210.

Research output: Contribution to journalArticle

10 Scopus citations

An NTS2 analog enhances the analgesic effects of morphine in an animal model of persistent pain and does not exhibit tolerance

Boules, M., Fredrickson, P. & Richelson, E., 2015, In : Open Pain Journal. 7, 1, p. 23-28 6 p.

Research output: Contribution to journalArticle

Open Access

A novel tau mutation, p.K317N, causes globular glial tauopathy

Tacik, P., DeTure, M., Lin, W. L., Sanchez Contreras, M., Wojtas, A., Hinkle, K. M., Fujioka, S., Baker, M. C., Walton, R. L., Carlomagno, Y., Brown, P. H., Strongosky, A. J., Kouri, N., Murray, M. E., Petrucelli, L., Josephs, K. A., Rademakers, R., Ross, O. A., Wszolek, Z. K. & Dickson, D. W., Aug 25 2015, In : Acta neuropathologica. 130, 2, p. 199-214 16 p.

Research output: Contribution to journalArticle

29 Scopus citations