Projects per year
- 1 - 50 out of 58 results
Search results
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Active
Nuclear import receptors as modifiers of TDP-43 phase transition and toxicity in FTD/ALS
Rossoll, W. & Shorter, J. J.
12/1/22 → 11/30/23
Project: Research project
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Discovery of apoE4 modulators for Alzheimer’s disease therapy
Liu, C., Chung, T. T. D. & Li, Y. Y.
9/30/22 → 5/31/23
Project: Research project
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Tau PET/CT for Early Detection of Alzheimer’s Disease Pathology
9/30/21 → 5/31/23
Project: Research project
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Discovery of novel TDP-43 splicing targets: the Achilles heel for FTD and towards sensitive biomarkers and therapeutic targets
Gitler, A. A. D., Fratta, P., Gitler, A. D., Petrucelli, L., Prudencio, M., Petrucelli, L., Prudencio, M., Fratta, P. P., Raj, T., Seeley, W. W., Raj, T. T. & Seeley, W. W. W.
National Institute of Neurological Disorders and Stroke
9/15/21 → 8/31/23
Project: Research project
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Human Biomarkers Core
Petrucelli, L. & Petrucelli, L.
National Institute of Neurological Disorders and Stroke
8/15/21 → 8/31/23
Project: Research project
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Poly(ADP-ribose) promotes the condensation and toxicity of C9orf72 arginine-rich dipeptide repeat proteins
Zhang, Y., Gendron, T. T. F., Gendron, T. D., Zhang, K. & Zhang, Y.
National Institute of Neurological Disorders and Stroke
7/15/21 → 6/30/23
Project: Research project
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Assessment of a novel tau propagation pathway from layer II medial entorhinal cortical neurons to CA1 pyramidal neurons as an early Braak stage mouse model
Ikezu, T. T. & Ikezu, T.
7/1/21 → 4/30/23
Project: Research project
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Biology and pathobiology of apoE in aging and Alzheimer's disease
Bu, G. D., Goate, A. A. M., Soranno, A. A., Liu, C., Holtzman, D. D. M., Dickson, D. W., Bowman, G. G. R., Peng, J. J., Kanekiyo, T., Asmann, Y., Asmann, Y. W., Bowman, G. R., Bu, G. D., Dickson, D. W., Goate, A. M., Holtzman, D. M., Kanekiyo, T., Liu, C. & Peng, J.
6/1/21 → 5/31/23
Project: Research project
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Molecular characterization of extracellular vesicles for the spread of misfolded tau protein
Ikezu, T. T. & Ikezu, T.
5/15/21 → 4/30/23
Project: Research project
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Enhanced APOE2 Expression into Brain for Therapeutic Strategy for Alzheimer's Disease
Singh, J. J., Kanekiyo, T., Singh, J. & Kanekiyo, T. T.
5/15/21 → 4/30/24
Project: Research project
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Stathmin-2 and TDP-43 neurodegeneration in Alzheimer?s and multi-etiology dementias
Josephs, K. A. & Prudencio, M.
National Institute of Neurological Disorders and Stroke
4/1/21 → 3/31/24
Project: Research project
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Endothelial cell senescence and APOE4 in vascular cognitive impairment and dementia
3/15/21 → 2/29/24
Project: Research project
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Single-Cell Transcriptional and Epigenomic Dissection to Identify Therapeutic Targets for ALS and FTD
Kellis, M. M., Belzil, V. & Kellis, M.
3/1/21 → 11/30/23
Project: Research project
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Dissecting neuron-microglia-astrocyte interaction in AD pathogenesis
Peng, J. & Rossoll, W.
9/15/20 → 8/31/24
Project: Research project
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Novel genetic modifiers of C9orf72 and Tau toxicity
Fryer, J. D. & Petrucelli, L.
8/15/20 → 3/31/24
Project: Research project
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Impact of T cells on the CNS during aging and Alzheimer’s disease
Kang, S. S. & Kang, S.
8/1/20 → 4/30/23
Project: Research project
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Mechanistic insights into the link between the A152T risk variant and tauopathy
Cook, C. & Cook, C. N.
4/15/20 → 3/31/23
Project: Research project
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Targeting emerging P2RX7 signaling pathways in animal models of Alzheimer's disease
2/1/20 → 2/28/23
Project: Research project
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Synergistic Interaction of amyloid-beta and alpha-synuclein in Lewy body Dementia
Dickson, D. D. W., Fitzpatrick, A. A. W., Peng, J. J., Ross, O. O. A., Mclean, P. P. J., Dickson, D. W., Fitzpatrick, A. W. P., McLean, P. J., Peng, J. & Ross, O. A.
National Institute of Neurological Disorders and Stroke
9/20/19 → 6/30/23
Project: Research project
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Molecular mechanisms of PINK1-PRKN directed mitochondrial quality control
National Institute of Neurological Disorders and Stroke
9/1/19 → 5/31/24
Project: Research project
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Microglial apoE in neuroinflammation and Alzheimer's disease
Fryer, J. D. & Liu, C.
8/1/19 → 3/31/24
Project: Research project
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Functional assessment of pathological α-syn and Aβ species in LBD
McLean, P. J. & Mclean, P. P. J.
7/1/19 → 6/30/23
Project: Research project
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Neuropathology and Biochemistry Core
Dickson, D. W. & Dickson, D. D. W.
7/1/19 → 6/30/23
Project: Research project
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-Omics driven network analysis in Lewy Body dementia
Ross, O. A. & Ross, O. O. A.
National Institute of Neurological Disorders and Stroke
7/1/19 → 6/30/23
Project: Research project
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Mayo Alzheimer's Disease Research Center Supplement (Identification and measurement of influences on brain donation decision making in African Americans)
Petersen, R. R. C., Boeve, B. F., Bu, G. D., Boeve, B. B. F., Knopman, D. S., Dickson, D. W., Dickson, D. W., Bu, G. G., Lucas, J. A., Kantarci, K. M., Kantarci, K. K., Knopman, D. S., Kremers, W. K., Lucas, J. A., Petersen, R. C. & Kremers, W. K.
7/1/19 → 4/30/23
Project: Research project
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Mitochondrial Sirtuin 3 in Parkinson's disease
Mclean, P. P. J., Springer, W., McLean, P. J. & Springer, W.
National Institute of Neurological Disorders and Stroke
6/1/19 → 5/31/23
Project: Research project
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Nuclear Pore Complex and as a Contributor to Tau Associated Dementia
Rothstein, J. D. & Petrucelli, L.
2/15/19 → 1/31/24
Project: Research project
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Patient-Based Structural Biology of Tauopathies and TDP-43 Proteinopathies using Cryo-Electron Microscopy and Mass Spectrometry
Fitzpatrick, A. A. W., Fitzpatrick, A. W. P., Steen, J. J. A., Petrucelli, L., Petrucelli, L. & Steen, J. A.
National Institute of Neurological Disorders and Stroke
9/30/18 → 8/31/23
Project: Research project
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Harnessing Molecular Networks of Resilience for Therapeutic Discoveries in AD
Ertekin-Taner, N. & Ertekin-Taner, N.
9/30/18 → 4/30/23
Project: Research project
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The Contribution of Age-Related Taupahtoies to Alzheimer's Disease-Supplement
Mckee, A. A. C., Crary, J. F., Dickson, D. W., Dickson, D. W., Crary, J. J. F. & McKee, A. C.
9/30/18 → 5/31/23
Project: Research project
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Pathophysiology of genetically defined dementia and neurodegeneration: Defining therapeutic targets and pathways
Disney, M. D., Petrucelli, L., Rothstein, J. D., Roush, W. R., Disney, M. M. D., Rothstein, J. J. D. & Petrucelli, L.
National Institute of Neurological Disorders and Stroke
6/15/17 → 4/30/23
Project: Research project
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Molecular Underpinnings of Clinical and Neuropathologic Heterogeneity in AD
1/1/17 → …
Project: Research project
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Expanding insights into FTD disease mechanisms
Petrucelli, L. L. & Petrucelli, L.
National Institute of Neurological Disorders and Stroke
12/1/16 → 11/30/23
Project: Research project
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APOE and microglia-mediated progression in tau pathology in AD
9/30/16 → 8/31/24
Project: Research project
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Molecular mechanisms of PABPN1-mediated suppression of TDP-43 toxicity
1/1/16 → …
Project: Research project
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Characterizing the contributions of epigenetic changes in c9FTD/ALS
1/1/14 → …
Project: Research project