Molecular Medicine

Research Output 1997 2020

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2020

Generation of a Tumor-Specific Chemokine Gradient Using Oncolytic Vesicular Stomatitis Virus Encoding CXCL9

Eckert, E. C., Nace, R. A., Tonne, J. M., Evgin, L., Vile, R. G. & Russell, S. J., Mar 27 2020, In : Molecular Therapy - Oncolytics. 16, p. 63-74 12 p.

Research output: Contribution to journalArticle

Open Access
Vesicular Stomatitis
Chemokines
Viruses
Neoplasms
T-Lymphocytes
2019

A comparison of adult rhabdomyosarcoma and high-grade neuroendocrine carcinoma of the urinary bladder reveals novel PPP1R12A fusions in rhabdomyosarcoma

Gupta, S., Sosa, C. P., Kosari, F., Folpe, A., Bhinge, K. N., Yang, L., Agahi, A., Johnson, S. H., Frank, I., Boorjian, S. A., Hansel, D. E., Al-Ahmadie, H. A., Reuter, V. E., Vasmatzis, G., Jimenez, R. E., Herrera-Hernandez, L. & Cheville, J., Jun 1 2019, In : Human Pathology. 88, p. 48-59 12 p.

Research output: Contribution to journalArticle

Neuroendocrine Carcinoma
Rhabdomyosarcoma
Urinary Bladder
RNA Sequence Analysis
Alveolar Rhabdomyosarcoma
2 Citations (Scopus)

Acute leukemias harboring KMT2A/MLLT10 fusion: a 10-year experience from a single genomics laboratory

Peterson, J. F., Sukov, W. R., Pitel, B. A., Smoley, S. A., Pearce, K. E., Meyer, R. G., Williamson, C. M., Smadbeck, J., Vasmatzis, G., Hoppman, N. L., Greipp, P. T., Baughn, L. & Ketterling, R. P., Jan 1 2019, In : Genes Chromosomes and Cancer.

Research output: Contribution to journalArticle

Genomics
Leukemia
Fluorescence In Situ Hybridization
Acute Myeloid Leukemia
Precursor Cell Lymphoblastic Leukemia-Lymphoma
3 Citations (Scopus)

A Modern Primer on Light Chain Amyloidosis in 592 Patients With Mass Spectrometry–Verified Typing

Muchtar, E., Gertz, M., Kyle, R. A., Lacy, M., Dingli, D. M., Leung, N., Buadi, F. K., Hayman, S. R., Kapoor, P., Hwa, Y. L., Fonder, A., Hobbs, M., Gonsalves, W., Kourelis, T., Warsame, R., Russell, S. J., Lust, J. A., Lin, Y., Go, R. S., Zeldenrust, S. & 3 others, Rajkumar, S. V., Kumar, S. K. & Dispenzieri, A., Mar 1 2019, In : Mayo Clinic proceedings. 94, 3, p. 472-483 12 p.

Research output: Contribution to journalArticle

Amyloidosis
Light
Kidney
Electrophoresis
Serum
1 Citation (Scopus)
Open Access
Alpharetrovirus
Glycoproteins
Viruses
Pressure
Virus Internalization
1 Citation (Scopus)

A VP35 Mutant Ebola Virus Lacks Virulence but Can Elicit Protective Immunity to Wild-Type Virus Challenge

Woolsey, C., Menicucci, A. R., Cross, R. W., Luthra, P., Agans, K. N., Borisevich, V., Geisbert, J. B., Mire, C. E., Fenton, K. A., Jankeel, A., Anand, S., Ebihara, H., Geisbert, T. W., Messaoudi, I. & Basler, C. F., Sep 17 2019, In : Cell reports. 28, 12, p. 3032-3046.e6

Research output: Contribution to journalArticle

Open Access
Ebolavirus
Viruses
Virulence
Immunity
Interferon Type I

Bone marrow plasma cells 20% or greater discriminate presentation, response, and survival in AL amyloidosis

Muchtar, E., Gertz, M. A., Kourelis, T. V., Sidana, S., Go, R. S., Lacy, M. Q., Buadi, F. K., Dingli, D., Hayman, S. R., Kapoor, P., Leung, N., Fonder, A., Hobbs, M., Lisa Hwa, Y., Gonsalves, W., Warsame, R., Russell, S., Lust, J. A., Lin, Y., Zeldenrust, S. & 4 others, Rajkumar, S. V., Kyle, R. A., Kumar, S. K. & Dispenzieri, A., Jan 1 2019, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

Amyloidosis
Plasma Cells
Bone Marrow Cells
Survival
Bone Marrow Diseases
2 Citations (Scopus)

Characterization of a cryptic IGH/CCND1 rearrangement in a case of mantle cell lymphoma with negative CCND1 FISH studies

Peterson, J. F., Baughn, L. B., Ketterling, R. P., Pitel, B. A., Smoley, S. A., Vasmatzis, G., Smadbeck, J. B., Greipp, P. T., Mangaonkar, A. A., Thompson, C. A., Parikh, S. A., Chen, D. & Viswanatha, D. S., Jan 1 2019, In : Blood Advances. 3, 8, p. 1298-1302 5 p.

Research output: Contribution to journalArticle

Open Access
Mantle-Cell Lymphoma
Cyclin D1
Fluorescence In Situ Hybridization
B-Cell Lymphoma
Cyclin D

Characterization of a rarely reported STAT5B/RARA gene fusion in a young adult with newly diagnosed acute promyelocytic leukemia with resistance to ATRA therapy

Peterson, J. F., He, R. R., Nayer, H., Cuevo, R. S., Smadbeck, J., Vasmatzis, G., Greipp, P. T., Ketterling, R. P., Hoppman, N. L. & Baughn, L., Sep 1 2019, In : Cancer Genetics. 237, p. 51-54 4 p.

Research output: Contribution to journalArticle

Acute Promyelocytic Leukemia
Gene Fusion
Tretinoin
Young Adult
Fluorescence In Situ Hybridization
1 Citation (Scopus)

Characterization of TCF3 rearrangements in pediatric B-lymphoblastic leukemia/lymphoma by mate-pair sequencing (MPseq) identifies complex genomic rearrangements and a novel TCF3/TEF gene fusion

Rowsey, R. A., Smoley, S. A., Williamson, C. M., Vasmatzis, G., Smadbeck, J. B., Ning, Y., Greipp, P. T., Hoppman, N. L., Baughn, L. B., Ketterling, R. P. & Peterson, J. F., Oct 1 2019, In : Blood cancer journal. 9, 10, 81.

Research output: Contribution to journalArticle

Open Access
Gene Fusion
Fluorescence In Situ Hybridization
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Pediatrics
Abnormal Karyotype
4 Citations (Scopus)

Comparative analysis of staging systems in AL amyloidosis

Muchtar, E., Therneau, T. M., Larson, D. R., Gertz, M., Lacy, M., Buadi, F. K., Dingli, D. M., Hayman, S. R., Kapoor, P., Gonsalves, W., Kourelis, T., Warsame, R., Fonder, A., Hobbs, M., Hwa, Y. L., Leung, N., Russell, S. J., Lust, J. A., Lin, Y., Go, R. S. & 5 others, Zeldenrust, S., Kyle, R. A., Rajkumar, S. V., Kumar, S. K. & Dispenzieri, A., Jan 1 2019, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

Amyloidosis
Systems Analysis
4 Citations (Scopus)

Cyclical adaptation of measles virus quasispecies to epithelial and lymphocytic cells: To V, or not to V

Donohue, R. C., Pfaller, C. K. & Cattaneo, R., Feb 1 2019, In : PLoS Pathogens. 15, 2, e1007605.

Research output: Contribution to journalArticle

Open Access
Measles virus
Epithelial Cells
RNA Editing
Genome
Proteins

Cytogenetic Features and Clinical Outcomes of Patients With Non-secretory Multiple Myeloma in the Era of Novel Agent Induction Therapy

Nandakumar, B., Kumar, S. K., Dispenzieri, A., Buadi, F. K., Dingli, D., Lacy, M. Q., Hayman, S. R., Kapoor, P., Leung, N., Fonder, A., Hobbs, M., Hwa, Y. L., Muchtar, E., Warsame, R., Kourelis, T. V., Russell, S., Lust, J. A., Lin, Y., Go, R. S., Siddiqui, M. & 5 others, Zeldenrust, S., Kyle, R. A., Gertz, M. A., Rajkumar, S. V. & Gonsalves, W. I., Jan 1 2019, (Accepted/In press) In : Clinical Lymphoma, Myeloma and Leukemia.

Research output: Contribution to journalArticle

Multiple Myeloma
Cytogenetics
Therapeutics
Survival
Plasma Cells
1 Citation (Scopus)

Detection of a cryptic NUP214/ABL1 gene fusion by mate-pair sequencing (MPseq) in a newly diagnosed case of pediatric T-lymphoblastic leukemia

Peterson, J. F., Pitel, B. A., Smoley, S. A., Smadbeck, J., Johnson, S. H., Vasmatzis, G., Koon, S. J., Webley, M. R., McGrath, M., Bayerl, M. G., Baughn, L., Rowsey, R. A., Ketterling, R. P., Greipp, P. T. & Hoppman, N. L., Apr 1 2019, In : Cold Spring Harbor molecular case studies. 5, 2

Research output: Contribution to journalArticle

Open Access
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Pediatrics
T-cells
Gene Fusion
Precursor Cell Lymphoblastic Leukemia-Lymphoma

Diverse immunotherapies can effectively treat syngeneic brainstem tumors in the absence of overt toxicity

Schuelke, M. R., Wongthida, P., Thompson, J., Kottke, T., Driscoll, C. B., Huff, A. L., Shim, K. G., Coffey, M., Pulido, J. S., Evgin, L. & Vile, R. G., Jul 17 2019, In : Journal for ImmunoTherapy of Cancer. 7, 1, 188.

Research output: Contribution to journalArticle

Open Access
Brain Stem Neoplasms
Immunotherapy
Brain Stem
Neoplasms
Pediatrics

Dual-Isotope SPECT Imaging with NIS Reporter Gene and Duramycin to Visualize Tumor Susceptibility to Oncolytic Virus Infection

Zhang, L., Suksanpaisan, L., Jiang, H., DeGrado, T. R., Russell, S. J., Zhao, M. & Peng, K. W., Dec 20 2019, In : Molecular Therapy - Oncolytics. 15, p. 178-185 8 p.

Research output: Contribution to journalArticle

Open Access
Oncolytic Viruses
Virus Diseases
Single-Photon Emission-Computed Tomography
Reporter Genes
Isotopes
2 Citations (Scopus)

Ebolavirus polymerase uses an unconventional genome replication mechanism

Deflubé, L. R., Cressey, T. N., Hume, A. J., Olejnik, J., Haddock, E., Feldmann, F., Ebihara, H., Fearns, R. & Mühlberger, E., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 17, p. 8535-8543 9 p.

Research output: Contribution to journalArticle

Ebolavirus
Nucleotides
Genome
RNA Viruses
RNA
2 Citations (Scopus)
Open Access
B-Cell Lymphoma
Fluorescence In Situ Hybridization
Non-Hodgkin's Lymphoma
Fluorescence
Cells
1 Citation (Scopus)

Enhanced noninvasive imaging of oncology models using the NIS reporter gene and bioluminescence imaging

Vandergaast, R., Khongwichit, S., Jiang, H., DeGrado, T. R., Peng, K-W., Smith, D. R., Russell, S. J. & Suksanpaisan, L., Jan 1 2019, (Accepted/In press) In : Cancer Gene Therapy.

Research output: Contribution to journalArticle

Reporter Genes
Neoplasms
Luciferases
Single-Photon Emission-Computed Tomography
Tumor Cell Line

Enhancing the R-ISS classification of newly diagnosed multiple myeloma by quantifying circulating clonal plasma cells

Gonsalves, W. I., Jevremovic, D., Nandakumar, B., Dispenzieri, A., Buadi, F. K., Dingli, D., Lacy, M. Q., Hayman, S. R., Kapoor, P., Leung, N., Fonder, A., Hobbs, M., Hwa, Y. L., Muchtar, E., Warsame, R., Kourelis, T. V., Russell, S., Lust, J. A., Lin, Y., Go, R. S. & 5 others, Siddiqui, M. A., Kyle, R. A., Gertz, M. A., Rajkumar, S. V. & Kumar, S. K., Jan 1 2019, (Accepted/In press) In : American journal of hematology.

Research output: Contribution to journalArticle

Plasma Cells
Multiple Myeloma
Survival
Flow Cytometry
Therapeutics

Hyperinsulinemic hypoglycemia subtype glucokinase V91L mutant induces necrosis in β-cells via ATP depletion

Lu, B., Tonne, J. M., Munoz-Gomez, M. & Ikeda, Y. H., Mar 1 2019, In : Biochemistry and Biophysics Reports. 17, p. 108-113 6 p.

Research output: Contribution to journalArticle

Glucokinase
Hypoglycemia
Necrosis
Adenosine Triphosphate
Cell death
6 Citations (Scopus)

Immune Cell Infiltration May Be a Key Determinant of Long-Term Survival in Small Cell Lung Cancer

Muppa, P., Parrilha Terra, S. B. S., Sharma, A., Mansfield, A., Aubry, M. C., Bhinge, K., Asiedu, M. K., De Andrade, M., Janaki, N., Murphy, S. J., Nasir, A., Van Keulen, V., Vasmatzis, G., Wigle, D. A., Yang, P., Yi, E. S., Peikert, T. D. & Kosari, F., Jul 1 2019, In : Journal of Thoracic Oncology. 14, 7, p. 1286-1295 10 p.

Research output: Contribution to journalArticle

Open Access
Small Cell Lung Carcinoma
Tumor Microenvironment
Survival Rate
Survivors
Survival
1 Citation (Scopus)

Immune modulation and immune-mediated pathogenesis of emerging tickborne banyangviruses

Mendoza, C. A., Ebihara, H. & Yamaoka, S., Dec 2019, In : Vaccines. 7, 4, 125.

Research output: Contribution to journalArticle

Open Access
Viruses
Thrombocytopenia
Fever
Virus Diseases
Vaccines
1 Citation (Scopus)

Impact of acquired del(17p) in multiple myeloma

Lakshman, A., Painuly, U., Vincent Rajkumar, S., Ketterling, R. P., Kapoor, P., Greipp, P. T., Dispenzieri, A., Gertz, M. A., Buadi, F. K., Lacy, M. Q., Dingli, D., Fonder, A. L., Hayman, S. R., Hobbs, M. A., Gonsalves, W. I., Hwa, Y. L., Leung, N., Go, R. S., Lin, Y., Kourelis, T. V. & 6 others, Warsame, R., Lust, J. A., Russell, S. J., Zeldenrust, S. R., Kyle, R. A. & Kumar, S. K., Jan 1 2019, In : Blood Advances. 3, 13, p. 1930-1938 9 p.

Research output: Contribution to journalArticle

Open Access
Multiple Myeloma
Survival
Confidence Intervals
Odds Ratio
Plasma Cells

Impact of prior diagnosis of monoclonal gammopathy on outcomes in newly diagnosed multiple myeloma

Goyal, G., Rajkumar, S. V., Lacy, M., Gertz, M., Buadi, F. K., Dispenzieri, A., Hwa, Y. L., Fonder, A. L., Hobbs, M. A., Hayman, S. R., Zeldenrust, S. R., Lust, J. A., Russell, S. J., Leung, N., Kapoor, P., Go, R. S., Gonsalves, W., Kourelis, T., Warsame, R., Kyle, R. A. & 1 others, Kumar, S. K., Jan 1 2019, In : Leukemia.

Research output: Contribution to journalArticle

Monoclonal Gammopathy of Undetermined Significance
Paraproteinemias
Multiple Myeloma
Plasmacytoma
Survival

Integration of Comprehensive Genomic Analysis and Functional Screening of Affected Molecular Pathways to Inform Cancer Therapy

Vasmatzis, G., Liu, M. C., Reganti, S., Feathers, R. W., Smadbeck, J., Johnson, S. H., Schaefer Klein, J. L., Harris, F. R., Yang, L., Kosari, F., Murphy, S. J., Borad, M. J., Thompson, E. A., Cheville, J. C. & Anastasiadis, P. Z., Jan 1 2019, (Accepted/In press) In : Mayo Clinic proceedings.

Research output: Contribution to journalArticle

Open Access
Neoplasms
Mutation
Therapeutics
Precision Medicine
Preclinical Drug Evaluations
1 Citation (Scopus)

Large Chromosomal Rearrangements Yield Biomarkers to Distinguish Low-Risk From Intermediate- and High-Risk Prostate Cancer

Vasmatzis, G., Kosari, F., Murphy, S. J., Terra, S., Kovtun, I. V., Harris, F. R., Zarei, S., Smadbeck, J., Johnson, S. H., Gaitatzes, A. G., Therneau, T. M., Rangel, L. J., Knudson, R. A., Greipp, P. T., Sukov, W. R., Knutson, D. L., Kloft-Nelson, S. M., Karnes, R. J. & Cheville, J., Jan 1 2019, In : Mayo Clinic Proceedings. 94, 1, p. 27-36 10 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Biomarkers
Area Under Curve
Neoplasm Grading
Needle Biopsy
9 Citations (Scopus)

Mate pair sequencing improves detection of genomic abnormalities in acute myeloid leukemia

Aypar, U., Smoley, S. A., Pitel, B. A., Pearce, K. E., Zenka, R. M., Vasmatzis, G., Johnson, S. H., Smadbeck, J., Peterson, J. F., Geiersbach, K. B., Van Dyke, D. L., Thorland, E. C., Jenkins, R. B., Ketterling, R. P., Greipp, P. T., Kearney, H. M., Hoppman, N. L. & Baughn, L., Jan 1 2019, In : European Journal of Haematology. 102, 1, p. 87-96 10 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Cytogenetics
Hematologic Neoplasms
Fluorescence In Situ Hybridization
Molecular Biology
2 Citations (Scopus)

Measles vector as a multiple genes delivery platform facilitating iPSC reprogramming

Wang, Q., Vossen, A., Ikeda, Y. H. & Devaux, P., Jan 1 2019, In : Gene Therapy.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Measles virus
Measles
Genes
Sendai virus

Measles virus ribonucleoprotein complexes rapidly spread across well-differentiated primary human airway epithelial cells along f-actin rings

Singh, B. K., Pfaller, C. K., Cattaneo, R. & Sinn, P. L., Nov 1 2019, In : mBio. 10, 6, e02434-19.

Research output: Contribution to journalArticle

Open Access
Measles virus
Ribonucleoproteins
Actins
Epithelial Cells
Epithelium
2 Citations (Scopus)
Open Access
Avian Sarcoma Viruses
Avian Leukosis Virus
Cercopithecine Herpesvirus 1
Antiviral Agents
Glycoproteins
1 Citation (Scopus)

Natural history of multiple myeloma with de novo del(17p)

Lakshman, A., Painuly, U., Rajkumar, S. V., Ketterling, R. P., Kapoor, P., Greipp, P. T., Gertz, M., Buadi, F. K., Lacy, M., Dingli, D. M., Dispenzieri, A., Fonder, A. L., Hayman, S. R., Hobbs, M. A., Gonsalves, W., Hwa, Y. L., Leung, N., Go, R. S., Lin, Y., Kourelis, T. & 6 others, Warsame, R., Lust, J. A., Russell, S. J., Zeldenrust, S. R., Kyle, R. A. & Kumar, S. K., Mar 1 2019, In : Blood cancer journal. 9, 3, 32.

Research output: Contribution to journalArticle

Open Access
Multiple Myeloma
Survival
Disease-Free Survival
Proteasome Inhibitors
Group Psychotherapy
16 Citations (Scopus)

Neoantigenic Potential of Complex Chromosomal Rearrangements in Mesothelioma

Mansfield, A., Peikert, T. D., Smadbeck, J., Udell, J. B. M., Garcia-Rivera, E., Elsbernd, L., Erskine, C. L., Van Keulen, V. P., Kosari, F., Murphy, S. J., Ren, H., Serla, V. V., Schaefer Klein, J. L., Karagouga, G., Harris, F. R., Sosa, C., Johnson, S. H., Nevala, W., Markovic, S. N., Bungum, A. O. & 6 others, Edell, E., Dong, H. M., Cheville, J., Aubry, M. C., Jen, J. & Vasmatzis, G., Feb 1 2019, In : Journal of Thoracic Oncology. 14, 2, p. 276-287 12 p.

Research output: Contribution to journalArticle

Mesothelioma
T-Lymphocytes
Carcinogens
Atlases
Asbestos
5 Citations (Scopus)

Phase I trial of an ICAM-1-targeted immunotherapeutic-coxsackievirus A21 (CVA21) as an oncolytic agent against non muscle-invasive bladder cancer

Annels, N. E., Mansfield, D., Arif, M., Ballesteros-Merino, C., Simpson, G. R., Denyer, M., Sandhu, S. S., Melcher, A. A., Harrington, K. J., Davies, B., Au, G., Grose, M., Bagwan, I., Fox, B., Vile, R., Mostafid, H., Shafren, D. & Pandha, H. S., Jan 1 2019, In : Clinical Cancer Research. 25, 19, p. 5818-5831 14 p.

Research output: Contribution to journalArticle

Enterovirus
Intercellular Adhesion Molecule-1
Urinary Bladder Neoplasms
Muscles
Mitomycin
1 Citation (Scopus)

Potentiating Oncolytic Virus-Induced Immune-Mediated Tumor Cell Killing Using Histone Deacetylase Inhibition

Jennings, V. A., Scott, G. B., Rose, A. M. S., Scott, K. J., Migneco, G., Keller, B., Reilly, K., Donnelly, O., Peach, H., Dewar, D., Harrington, K. J., Pandha, H., Samson, A., Vile, R. G., Melcher, A. A. & Errington-Mais, F., Jan 1 2019, In : Molecular Therapy.

Research output: Contribution to journalArticle

Open Access
Oncolytic Viruses
Histone Deacetylases
Granulocyte-Macrophage Colony-Stimulating Factor
Simplexvirus
Natural Killer Cells

Prevalence and Strains of Colorado Tick Fever Virus in Rocky Mountain Wood Ticks in the Bitterroot Valley, Montana

Williamson, B. N., Fischer, R. J., Lopez, J. E., Ebihara, H. & Schwan, T. G., Sep 1 2019, In : Vector-Borne and Zoonotic Diseases. 19, 9, p. 694-702 9 p.

Research output: Contribution to journalArticle

Colorado tick fever virus
Ticks
Coltivirus
Rickettsia rickettsii
Reoviridae
1 Citation (Scopus)
Open Access
Morbillivirus
Canine Distemper Virus
Measles virus
Chimerism
Immune Sera
1 Citation (Scopus)

Prognostic restaging at the time of second-line therapy in patients with AL amyloidosis

Hwa, Y. L., Gertz, M., Kumar, S. K., Lacy, M., Buadi, F. K., Dingli, D. M., Kapoor, P., Zeldenrust, S. R., Leung, N., Hayman, S. R., Gonsalves, W., Kourelis, T., Warsame, R., Go, R. S., Muchtar, E., Hobbs, M. A., Fonder, A. L., Russell, S. J., Kyle, R. A., Rajkumar, S. V. & 1 others, Dispenzieri, A., Jan 1 2019, In : Leukemia.

Research output: Contribution to journalArticle

Amyloidosis
Stem Cells
Therapeutics
Transplants
Survival
1 Citation (Scopus)

Prognostic value of minimal residual disease and polyclonal plasma cells in myeloma patients achieving a complete response to therapy

Tschautscher, M. A., Jevremovic, D., Rajkumar, S. V., Dispenzieri, A., Lacy, M., Gertz, M., Buadi, F. K., Dingli, D. M., Hwa, Y. L., Fonder, A. L., Hobbs, M. A., Hayman, S. R., Zeldenrust, S. R., Lust, J. A., Russell, S. J., Leung, N., Kapoor, P., Go, R. S., Lin, Y., Gonsalves, W. & 4 others, Kourelis, T., Warsame, R., Kyle, R. A. & Kumar, S. K., Jan 1 2019, In : American journal of hematology.

Research output: Contribution to journalArticle

Residual Neoplasm
Multiple Myeloma
Survival
Plasma Cells
Therapeutics
1 Citation (Scopus)

RNA Virus-Based Episomal Vector with a Fail-Safe Switch Facilitating Efficient Genetic Modification and Differentiation of iPSCs

Komatsu, Y., Takeuchi, D., Tokunaga, T., Sakurai, H., Makino, A., Honda, T., Ikeda, Y. H. & Tomonaga, K., Sep 13 2019, In : Molecular Therapy - Methods and Clinical Development. 14, p. 47-55 9 p.

Research output: Contribution to journalArticle

Open Access
RNA Viruses
Induced Pluripotent Stem Cells
Stem Cells
Borna disease virus
Gene Transfer Techniques
1 Citation (Scopus)

Shared and unique genomic structural variants of different histological components within testicular germ cell tumours identified with mate pair sequencing

Bryce, A. H., Egan, J. B., Smadbeck, J., Johnson, S. H., Murphy, S. J., Harris, F. R., Halling, G. C., Terra, S. B. S. P., Cheville, J., Pagliaro, L., Leibovich, B., Costello, B. & Vasmatzis, G., Dec 1 2019, In : Scientific reports. 9, 1, 3586.

Research output: Contribution to journalArticle

Open Access
Genomic Structural Variation
Exome
Histology
Neoplasms
Protein Isoforms
3 Citations (Scopus)

Structural and functional analyses reveal promiscuous and species specific use of ephrin receptors by Cedar virus

Laing, E. D., Navaratnarajah, C. K., da Silva, S. C., Petzing, S. R., Xu, Y., Sterling, S. L., Marsh, G. A., Wang, L. F., Amaya, M., Nikolov, D. B., Cattaneo, R., Broder, C. C. & Xu, K., Oct 8 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 41, p. 20707-20715 9 p.

Research output: Contribution to journalArticle

Open Access
Henipavirus
Eph Family Receptors
Ephrin-A1
Ephrin-B1
Ephrin-B2
2 Citations (Scopus)

Suboptimal T-cell Therapy Drives a Tumor Cell Mutator Phenotype That Promotes Escape from First-Line Treatment

Evgin, L., Huff, A. L., Kottke, T., Thompson, J., Molan, A. M., Driscoll, C. B., Schuelke, M., Shim, K. G., Wongthida, P., Ilett, E. J., Smith, K. K., Harris, R. S., Coffey, M., Pulido, J. S., Pandha, H., Selby, P. J., Harrington, K. J., Melcher, A. & Vile, R. G., May 1 2019, In : Cancer Immunology Research. 7, 5, p. 828-840 13 p.

Research output: Contribution to journalArticle

Cell- and Tissue-Based Therapy
T-Lymphocytes
Phenotype
Neoplasms
Genetic Therapy

Substratification of patients with newly diagnosed standard-risk multiple myeloma

Binder, M., Rajkumar, S. V., Ketterling, R. P., Dispenzieri, A., Lacy, M., Gertz, M., Buadi, F. K., Hayman, S. R., Hwa, Y. L., Zeldenrust, S. R., Lust, J. A., Russell, S. J., Leung, N., Kapoor, P., Go, R. S., Gonsalves, W., Kyle, R. A. & Kumar, S. K., Jan 1 2019, In : British journal of haematology.

Research output: Contribution to journalArticle

Multiple Myeloma
Survival
Confidence Intervals
Abnormal Karyotype
Lymphocyte Count

Survival impact of achieving minimal residual negativity by multi-parametric flow cytometry in AL amyloidosis

Muchtar, E., Dispenzieri, A., Jevremovic, D., Dingli, D., Buadi, F. K., Lacy, M. Q., Gonsalves, W., Warsame, R., Kourelis, T. V., Hayman, S. R., Kapoor, P., Leung, N., Russell, S., Lust, J. A., Lin, Y., Go, R. S., Zeldenrust, S., Kyle, R. A., Rajkumar, S. V., Kumar, S. K. & 1 others, Gertz, M. A., Jan 1 2019, (Accepted/In press) In : Amyloid.

Research output: Contribution to journalArticle

Amyloidosis
Plasma Cells
Flow Cytometry
Survival
Disease-Free Survival
5 Citations (Scopus)

Targeting glycogen synthase kinase 3 for therapeutic benefit in lymphoma

Wu, X., Stenson, M., Abeykoon, J., Nowakowski, K., Zhang, L., Lawson, J., Wellik, L., Li, Y., Krull, J., Wenzl, K., Novak, A. J., Ansell, S. M., Bishop, G. A., Billadeau, D. D., Peng, K. W., Giles, F., Schmitt, D. M. & Witzig, T. E., Jul 25 2019, In : Blood. 134, 4, p. 363-373 11 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Lymphoma
Therapeutics
B-Lymphocytes
Clustered Regularly Interspaced Short Palindromic Repeats
32 Citations (Scopus)

Taxonomy of the order Bunyavirales: second update 2018

Maes, P., Adkins, S., Alkhovsky, S. V., Avšič-Županc, T., Ballinger, M. J., Bente, D. A., Beer, M., Bergeron, É., Blair, C. D., Briese, T., Buchmeier, M. J., Burt, F. J., Calisher, C. H., Charrel, R. N., Choi, I. R., Clegg, J. C. S., de la Torre, J. C., de Lamballerie, X., DeRisi, J. L., Digiaro, M. & 58 others, Drebot, M., Ebihara, H., Elbeaino, T., Ergünay, K., Fulhorst, C. F., Garrison, A. R., Gāo, G. F., Gonzalez, J. P. J., Groschup, M. H., Günther, S., Haenni, A. L., Hall, R. A., Hewson, R., Hughes, H. R., Jain, R. K., Jonson, M. G., Junglen, S., Klempa, B., Klingström, J., Kormelink, R., Lambert, A. J., Langevin, S. A., Lukashevich, I. S., Marklewitz, M., Martelli, G. P., Mielke-Ehret, N., Mirazimi, A., Mühlbach, H. P., Naidu, R., Nunes, M. R. T., Palacios, G., Papa, A., Pawęska, J. T., Peters, C. J., Plyusnin, A., Radoshitzky, S. R., Resende, R. O., Romanowski, V., Sall, A. A., Salvato, M. S., Sasaya, T., Schmaljohn, C., Shí, X., Shirako, Y., Simmonds, P., Sironi, M., Song, J. W., Spengler, J. R., Stenglein, M. D., Tesh, R. B., Turina, M., Wèi, T., Whitfield, A. E., Yeh, S. D., Zerbini, F. M., Zhang, Y. Z., Zhou, X. & Kuhn, J. H., Jan 1 2019, (Accepted/In press) In : Archives of Virology.

Research output: Contribution to journalArticle

Arenaviridae
Viruses
20 Citations (Scopus)

Taxonomy of the order Bunyavirales: update 2019

Abudurexiti, A., Adkins, S., Alioto, D., Alkhovsky, S. V., Avšič-Županc, T., Ballinger, M. J., Bente, D. A., Beer, M., Bergeron, É., Blair, C. D., Briese, T., Buchmeier, M. J., Burt, F. J., Calisher, C. H., Cháng, C., Charrel, R. N., Choi, I. R., Clegg, J. C. S., de la Torre, J. C., de Lamballerie, X. & 83 others, Dèng, F., Di Serio, F., Digiaro, M., Drebot, M. A., Duàn, X., Ebihara, H., Elbeaino, T., Ergünay, K., Fulhorst, C. F., Garrison, A. R., Gāo, G. F., Gonzalez, J. P. J., Groschup, M. H., Günther, S., Haenni, A. L., Hall, R. A., Hepojoki, J., Hewson, R., Hú, Z., Hughes, H. R., Jonson, M. G., Junglen, S., Klempa, B., Klingström, J., Kòu, C., Laenen, L., Lambert, A. J., Langevin, S. A., Liu, D., Lukashevich, I. S., Luò, T., Lǚ, C., Maes, P., de Souza, W. M., Marklewitz, M., Martelli, G. P., Matsuno, K., Mielke-Ehret, N., Minutolo, M., Mirazimi, A., Moming, A., Mühlbach, H. P., Naidu, R., Navarro, B., Nunes, M. R. T., Palacios, G., Papa, A., Pauvolid-Corrêa, A., Pawęska, J. T., Qiáo, J., Radoshitzky, S. R., Resende, R. O., Romanowski, V., Sall, A. A., Salvato, M. S., Sasaya, T., Shěn, S., Shí, X., Shirako, Y., Simmonds, P., Sironi, M., Song, J. W., Spengler, J. R., Stenglein, M. D., Sū, Z., Sūn, S., Táng, S., Turina, M., Wáng, B., Wáng, C., Wáng, H., Wáng, J., Wèi, T., Whitfield, A. E., Zerbini, F. M., Zhāng, J., Zhāng, L., Zhāng, Y., Zhang, Y. Z., Zhāng, Y., Zhou, X., Zhū, L. & Kuhn, J. H., Jul 1 2019, In : Archives of Virology. 164, 7, p. 1949-1965 17 p.

Research output: Contribution to journalArticle

Open Access
Viruses
1 Citation (Scopus)

Ten-year survivors in AL amyloidosis: characteristics and treatment pattern

Muchtar, E., Gertz, M., Lacy, M., Go, R. S., Buadi, F. K., Dingli, D. M., Grogan, M., Abou Ezzeddine, O., Hayman, S. R., Kapoor, P., Leung, N., Fonder, A., Hobbs, M., Hwa, Y. L., Gonsalves, W., Warsame, R., Kourelis, T., Russell, S. J., Lust, J. A., Lin, Y. & 5 others, Zeldenrust, S., Kyle, R. A., Rajkumar, S. V., Kumar, S. K. & Dispenzieri, A., Jan 1 2019, In : British journal of haematology.

Research output: Contribution to journalArticle

Amyloidosis
Survivors
Survival
Therapeutics
Trisomy
5 Citations (Scopus)

Trans-endocytosis elicited by nectins transfers cytoplasmic cargo, including infectious material, between cells

Generous, A. R., Harrison, O. J., Troyanovsky, R. B., Mateo, M., Navaratnarajah, C. K., Donohue, R. C., Pfaller, C. K., Alekhina, O., Sergeeva, A. P., Indra, I., Thornburg, T., Kochetkova, I., Billadeau, D. D., Taylor, M. P., Troyanovsky, S. M., Honig, B., Shapiro, L. & Cattaneo, R., Aug 23 2019, In : Journal of cell science. 132, 16

Research output: Contribution to journalArticle

Open Access
Endocytosis
Measles virus
nectins
Cytoplasm
Epithelial Cells