Molecular Medicine

Research output

Research output per year 1981 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024

• 1419 Article
• 148 Review article
• 42 Comment/debate
• 27 Letter
• 54 More
  • 26 Chapter
  • 13 Editorial
  • 13 Short survey
  • 2 Conference contribution

Research output per year

Research output per year

Search results

• 2024

  Analysis of antiviral drug properties of thymidine kinase of herpes B virus using recombinant herpes simplex virus 1

  Nguyen, P. H. A., Fukushi, S., Yamada, S., Harada, S., Yoshikawa, T., Kinoshita, H., Kawahara, M., Ogawa, T., Ebihara, H., Moi, M. L. & Saijo, M., Jan 11 2024, In: Microbiology Spectrum. 12, 1, p. e0309123

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Macacine alphaherpesvirus 1 100%
  • antiviral agents 86%
  • Cercopithecine Herpesvirus 1 84%
  • thymidine kinase 80%
  • Human alphaherpesvirus 1 79%

• Carcinoembryonic antigen-expressing oncolytic measles virus derivative in recurrent glioblastoma: a phase 1 trial

  Galanis, E., Dooley, K. E., Keith Anderson, S., Kurokawa, C. B., Carrero, X. W., Uhm, J. H., Federspiel, M. J., Leontovich, A. A., Aderca, I., Viker, K. B., Hammack, J. E., Marks, R. S., Robinson, S. I., Johnson, D. R., Kaufmann, T. J., Buckner, J. C., Lachance, D. H., Burns, T. C., Giannini, C., Raghunathan, A., & 2 othersIankov, I. D. & Parney, I. F., Dec 2024, In: Nature communications. 15, 1, 493.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Oncolytic 100%
  • Oncolytic Viruses 79%
  • Measles virus 72%
  • antigens 72%
  • viruses 67%

• Complex balanced intrachromosomal rearrangement involving PITX2 identified as a cause of Axenfeld-Rieger Syndrome

  Farris, J., Khanna, C., Smadbeck, J. B., Johnson, S. H., Bothun, E., Kaplan, T., Hoffman, F., Polonis, K., Oliver, G., Reis, L. M., Semina, E. V., Rust, L., Hoppman, N. L., Vasmatzis, G., Marcou, C. A., Schimmenti, L. A. & Klee, E. W., 2024, (Accepted/In press) In: American Journal of Medical Genetics, Part A.

  Research output: Contribution to journal › Article › peer-review

  • Axenfeld-Rieger syndrome 100%
  • Computational Biology 37%
  • Meckel Diverticulum 28%
  • Genome 26%
  • Exome 23%

• Evasive Spike Variants Elucidate the Preservation of T Cell Immune Response to the SARS-CoV-2 Omicron Variant

  Solanki, A., Cornette, J., Udell, J., Vasmatzis, G. & Riedel, M., 2024, (Accepted/In press) In: IEEE/ACM Transactions on Computational Biology and Bioinformatics. p. 1-11 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Severe Acute Respiratory Syndrome 100%
  • T-cells 95%
  • SARS Virus 94%
  • Immune Response 82%
  • Spike 73%

• From pandemic to endemic: Divergence of COVID-19 positive-tests and hospitalization numbers from SARS-CoV-2 RNA levels in wastewater of Rochester, Minnesota

  Majumdar, R., Taye, B., Bjornberg, C., Giljork, M., Lynch, D., Farah, F., Abdullah, I., Osiecki, K., Yousaf, I., Luckstein, A., Turri, W., Sampathkumar, P., Moyer, A. M., Kipp, B. R., Cattaneo, R., Sussman, C. R. & Navaratnarajah, C. K., Mar 30 2024, In: Heliyon. 10, 6, e27974.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Macacine alphaherpesvirus 1 (B Virus) Infection in Humans, Japan, 2019

  Yamada, S., Katano, H., Sato, Y., Suzuki, T., Uda, A., Ishijima, K., Suzuki, M., Yamada, D., Harada, S., Kinoshita, H., Nguyen, P. H. A., Ebihara, H., Maeda, K., Saijo, M. & Fukushi, S., Jan 2024, In: Emerging infectious diseases. 30, 1, p. 177-179 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cercopithecine Herpesvirus 1 100%
  • Herpesviridae Infections 94%
  • Japan 60%
  • Macaca 27%
  • Cerebrospinal Fluid 21%

• Maternal SARS-CoV-2 infection in pregnancy disrupts gene expression in Hofbauer cells with limited impact on cytotrophoblasts

  Enninga, E. A. L., Quach, H. Q., Jang, J. S., de Araujo Correia, M. C. M., Fedyshyn, Y., Fedyshyn, B., Lemens, M., Littlefield, D., Behl, S., Sintim-Aboagye, E., Plazas, M. C. M., Cardenas, M. C., Chakraborty, S., Yamaoka, S., Ebihara, H., Pandey, A., Li, H., Badley, A. D., Johnson, E. L., Sun, J., & 3 othersNorgan, A. P., Theiler, R. N. & Chakraborty, R., Feb 2024, In: PLoS pathogens. 20, 2 February, e1011990.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • SARS Virus 100%
  • Trophoblasts 74%
  • pregnancy 50%
  • Mothers 43%
  • gene expression 41%

• Mutations in the 3′ non-coding region of a no-known vector flavivirus Yokose virus increased its replication ability in mosquito C6/36 cells

  Tajima, S., Kataoka, M., Takamatsu, Y., Ebihara, H. & Lim, C. K., Jan 2024, In: Virology. 589, 109928.

  Research output: Contribution to journal › Article › peer-review

  • Flavivirus 100%
  • Culicidae 83%
  • Viruses 52%
  • Mutation 43%
  • Japanese Encephalitis Virus 9%

• Oncolytic α-herpesvirus and myeloid-tropic cytomegalovirus cooperatively enhance systemic antitumor responses

  Jiang, H., Nace, R., Ariail, E., Ma, Y., McGlinch, E., Ferguson, C., Fernandez Carrasco, T., Packiriswamy, N., Zhang, L., Peng, K. W. & Russell, S. J., Jan 3 2024, In: Molecular Therapy. 32, 1, p. 241-256 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Oncolytic 100%
  • Herpesviridae 65%
  • Simplexvirus 62%
  • Cytomegalovirus 56%
  • Antitumor 52%

• Pathological and virological findings of type I interferon receptor knockout mice upon experimental infection with Heartland virus

  Fujii, H., Fukushi, S., Yoshikawa, T., Nagata, N., Taniguchi, S., Shimojima, M., Yamada, S., Tani, H., Uda, A., Maeki, T., Harada, S., Kurosu, T., Lim, C. K., Nakayama, E., Takayama-Ito, M., Watanabe, S., Ebihara, H., Morikawa, S. & Saijo, M., Feb 2024, In: Virus Research. 340, 199301.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Interferon alpha-beta Receptor 100%
  • Knockout Mice 61%
  • Viruses 44%
  • Infections 31%
  • Lymph Nodes 17%

• Surface-modified measles vaccines encoding oligomeric, prefusion-stabilized SARS-CoV-2 spike glycoproteins boost neutralizing antibody responses to Omicron and historical variants, independent of measles seropositivity

  Muñoz-Alía, M., Nace, R. A., Balakrishnan, B., Zhang, L., Packiriswamy, N., Singh, G., Warang, P., Mena, I., Narjari, R., Vandergaast, R., Peng, K. W., García-Sastre, A., Schotsaert, M. & Russell, S. J., Feb 2024, In: mBio. 15, 2

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Vertical Transmission of SARS-CoV-2–Specific Antibodies and Cytokine Profiles in Pregnancy

  Monroe, J. M., Quach, H. Q., Punia, S., Enninga, E. A. L., Fedyshyn, Y., Girsch, J. H., Fedyshyn, B., Lemens, M., Littlefield, D., Behl, S., Sintim-Aboagye, E., Mejia Plazas, M. C., Yamaoka, S., Ebihara, H., Pandey, A., Correia, C., Ung, C. Y., Li, H., Vassallo, R., Sun, J., & 7 othersJohnson, E. L., Olson, J. E., Theel, E. S., Badley, A. D., Kennedy, R. B., Theiler, R. N. & Chakraborty, R., Feb 15 2024, In: Journal of Infectious Diseases. 229, 2, p. 473-484 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • SARS Virus 100%
  • Mothers 43%
  • Cytokines 42%
  • Pregnancy 40%
  • Antibodies 37%
• 2023

  Anti–PD-1 and Extended Half-life IL2 Synergize for Treatment of Murine Glioblastoma Independent of Host MHC Class I Expression

  Tritz, Z. P., Ayasoufi, K., Wolf, D. M., Owens, C. A., Malo, C. S., Himes, B. T., Fain, C. E., Goddery, E. N., Yokanovich, L. T., Jin, F., Hansen, M. J., Parney, I. F., Wang, C., Moynihan, K. D., Irvine, D. J., Wittrup, K. D., Diaz Marcano, R. M., Vile, R. G. & Johnson, A. J., Jun 1 2023, In: Cancer Immunology Research. 11, 6, p. 763-766 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Glioblastoma 100%
  • Interleukin-2 90%
  • Half-Life 89%
  • Glioma 62%
  • Survival 56%

• A phase I oncolytic virus trial with vesicular stomatitis virus expressing human interferon beta and tyrosinase related protein 1 administered intratumorally and intravenously in uveal melanoma: safety, efficacy, and T cell responses

  Smith, K. E. R., Peng, K. W., Pulido, J. S., Weisbrod, A. J., Strand, C. A., Allred, J. B., Newsom, A. N., Zhang, L., Packiriswamy, N., Kottke, T., Tonne, J. M., Moore, M., Montane, H. N., Kottschade, L. A., McWilliams, R. R., Dudek, A. Z., Yan, Y., Dimou, A., Markovic, S. N., Federspiel, M. J., & 3 othersVile, R. G., Dronca, R. S. & Block, M. S., 2023, In: Frontiers in immunology. 14, 1279387.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Tyrosine Phenol-Lyase 100%
  • tyrosinase-related protein-1 79%
  • Oncolytic Viruses 68%
  • Uveal melanoma 65%
  • Vesicular Stomatitis 63%

• A single-center assessment of mental health and well-being in a biomedical sciences graduate program

  Jachim, S. K., Bowles, B. S., Panicker, A. J., Yousaf, I., Brown, A. D., Zoroufy, A. J., Boehmer, K. R., Stonnington, C. M., Vadeboncoeur, T. F., Lujan, J. L., Ehlers, S. L. & Schulze, A. J., May 2023, In: Nature biotechnology. 41, 5, p. 728-733 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Brain tropism acquisition: The spatial dynamics and evolution of a measles virus collective infectious unit that drove lethal subacute sclerosing panencephalitis

  Yousaf, I., Hannon, W. W., Donohue, R. C., Pfaller, C. K., Yadav, K., Dikdan, R. J., Tyagi, S., Schroeder, D. C., Shieh, W. J., Rota, P. A., Feder, A. F. & Cattaneo, R., Dec 2023, In: PLoS pathogens. 19, 12 December, e1011817.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Measles morbillivirus 100%
  • Subacute Sclerosing Panencephalitis 99%
  • tropisms 93%
  • Measles virus 87%
  • Tropism 82%

• Characterization of Morreton virus as an oncolytic virotherapy platform for liver cancers

  Nagalo, B. M., Zhou, Y., Loeuillard, E. J., Dumbauld, C., Barro, O., Elliott, N. M., Baker, A. T., Arora, M., Bogenberger, J. M., Meurice, N., Petit, J., Uson, P. L. S., Aslam, F., Raupach, E., Gabere, M., Basnakian, A., Simoes, C. C., Cannon, M. J., Post, S. R., Buetow, K., & 9 othersChamcheu, J. C., Barrett, M. T., Duda, D. G., Jacobs, B., Vile, R., Barry, M. A., Roberts, L. R., Ilyas, S. & Borad, M. J., Jun 2023, In: Hepatology. 77, 6, p. 1943-1957 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Oncolytic Virotherapy 100%
  • Liver Neoplasms 64%
  • Viruses 43%
  • Cholangiocarcinoma 33%
  • Vesicular Stomatitis 18%

• Comparative gene expression profiling reveals differential expression of GATA3 and Wnt signaling in juxtaglomerular cell tumors compared to renal glomus tumors

  Kosari, F., Sosa, C., Kilic, I., Acosta, A. M., Raghunathan, A., Herrera Hernandez, L., Sharma, V., Cheville, J. C. & Gupta, S., Sep 2023, In: Human Pathology. 139, p. 138-140 3 p.

  Research output: Contribution to journal › Letter › peer-review

• Construction of a recombinant vaccine expressing Nipah virus glycoprotein using the replicative and highly attenuated vaccinia virus strain LC16m8

  Watanabe, S., Yoshikawa, T., Kaku, Y., Kurosu, T., Fukushi, S., Sugimoto, S., Nishisaka, Y., Fuji, H., Marsh, G., Maeda, K., Ebihara, H., Morikawa, S., Shimojima, M. & Saijo, M., Dec 2023, In: PLoS Neglected Tropical Diseases. 17, 12, e0011851.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Nipah Virus 100%
  • Synthetic Vaccines 78%
  • Vaccinia virus 75%
  • Glycoproteins 53%
  • clinical use 42%

• Current Status and Challenges of Oncolytic Virotherapy for the Treatment of Glioblastoma

  Webb, M. J., Sener, U. & Vile, R. G., Jun 2023, In: Pharmaceuticals. 16, 6, 793.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Oncolytic 100%
  • Oncolytic Virotherapy 87%
  • Glioblastoma 56%
  • Chimeric Antigen Receptors 10%
  • Clinical Trials 10%

• Dengue virus infection induces selective expansion of Vγ4 and Vγ6TCR γδ T cells in the small intestine and a cytokine storm driving vascular leakage in mice

  Kurosu, T., Okuzaki, D., Sakai, Y., Kadi, M. A., Phanthanawiboon, S., Ami, Y., Shimojima, M., Yoshikawa, T., Fukushi, S., Nagata, N., Suzuki, T., Kamimura, D., Murakami, M., Ebihara, H. & Saijo, M., Nov 2023, In: PLoS Neglected Tropical Diseases. 17, 11 November, e0011743.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Small Intestine 77%
  • Interleukin-17 74%
  • Virus Diseases 62%
  • Severe Dengue 56%
  • permeability 54%

• Direct early growth response-1 knockdown decreases melanoma viability independent of mitogen-activated extracellular signal-related kinase inhibition

  Miley, D. R., Andrews-Pfannkoch, C. M., Pulido, J. S., Erickson, S. A., Vile, R. G., Fautsch, M. P., Marmorstein, A. D. & Dalvin, L. A., Dec 1 2023, In: Melanoma research. 33, 6, p. 482-491 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Mitogens 100%
  • Melanoma 82%
  • Phosphotransferases 76%
  • Mitogen-Activated Protein Kinases 68%
  • Protein Kinase Inhibitors 52%

• Dynamics and survival associations of T cell receptor clusters in patients with pleural mesothelioma treated with immunotherapy

  Desai, A. P., Kosari, F., Disselhorst, M., Yin, J., Agahi, A., Peikert, T., Udell, J., Johnson, S. H., Smadbeck, J., Murphy, S., Karagouga, G., McCune, A., Schaefer-Klein, J., Borad, M. J., Cheville, J., Vasmatzis, G., Baas, P. & Mansfield, A., Jun 6 2023, In: Journal for ImmunoTherapy of Cancer. 11, 6, e006035.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mesothelioma 100%
  • T-Cell Antigen Receptor 85%
  • Immunotherapy 74%
  • Survival 46%
  • Complementarity Determining Regions 42%

• Efficacy and viral dynamics of tecovirimat in patients with MPOX: A multicenter open-label, double-arm trial in Japan

  Akiyama, Y., Morioka, S., Tsuzuki, S., Yoshikawa, T., Yamato, M., Nakamura, H., Shimojima, M., Takakusaki, M., Saito, S., Takahashi, K., Sanada, M., Komatsubara, M., Takebuchi, K., Yamaguchi, E., Suzuki, T., Shimokawa, K., Kurosu, T., Kawahara, M., Oishi, K., Ebihara, H., & 1 othersOhmagari, N., 2023, (Accepted/In press) In: Journal of Infection and Chemotherapy.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • ST-246 100%
  • Japan 42%
  • HIV 12%
  • Virus Shedding 12%
  • 3-(2-methoxyphenyl)-5-methoxy-1,3,4-oxadiazol-2(3H)-one 8%

• Epigenomics may begin to explain in vitro differential response to hypomethylating agents in MMR-D hypermethylated endometrial cancer

  El Khoury, L. Y., Lin, W. H., Smadbeck, J. B., Barrett, M. T., Sadeghian, D., Mccune, A. F., Karagouga, G., Cheville, J. C., Harris, F. R., Kinsella, L. M., Feathers, R. W., Schafer Klein, J. L., Walther-Antonio, M. R. S., Johnson, S. H., Penheiter, A. R., Cucinella, G., Schivardi, G., Bhagwate, A., Borad, M. J., Mansfield, A. S., & 6 othersMurphy, S. J., Mariani, A., Vasmatzis, G., Anastasiadis, P. Z., Weroha, S. J. & Larish, A. M., Mar 1 2023, In: Epigenomics. 15, 5, p. 283-292 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Endometrial Neoplasms 100%
  • Epigenomics 85%
  • Azacitidine 64%
  • Decitabine 62%
  • DNA 54%

• Evaluating NetMHCpan performance on non-European HLA alleles not present in training data

  Atkins, T. K., Solanki, A., Vasmatzis, G., Cornette, J. & Riedel, M., 2023, In: Frontiers in immunology. 14, 1288105.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Evaluating the Immunogenicity and Safety of a Smallpox Vaccine to Monkeypox in Healthy Japanese Adults: A Single-Arm Study

  Tomita, N., Morino, E., Terada-Hirashima, J., Uemura, Y., Shimizu, Y., Saito, S., Suzuki, T., Okumura, N., Iwasaki, H., Ebihara, H., Shimojima, M., Sugiura, W., Ohmagari, N. & Ujiie, M., Mar 2023, In: Life. 13, 3, 787.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • smallpox 100%
  • Monkeypox virus 81%
  • Monkeypox 78%
  • vaccines 74%
  • Smallpox Vaccine 72%

• Evaluation of a novel severe combined immunodeficiency mouse model for antiviral drug evaluation against Chandipura virus infection

  Kitaura, S., Tobiume, M., Kawahara, M., Satoh, M., Kato, H., Nakayama, N., Nakajima, N., Komeno, T., Furuta, Y., Suzuki, T., Moriya, K., Saijo, M., Ebihara, H. & Takayama-Ito, M., May 2023, In: Antiviral Research. 213, 105582.

  Research output: Contribution to journal › Article › peer-review

  • Vesiculovirus 100%
  • favipiravir 98%
  • Severe Combined Immunodeficiency 70%
  • Drug Evaluation 68%
  • Antiviral Agents 47%

• GENETIC VARIATION OF LEPTOTROMBIDIUM (ACARI: TROMBICULIDAE) MITES CARRYING ORIENTIA TSUTSUGAMUSHI, THE BACTERIAL PATHOGEN CAUSING SCRUB TYPHUS

  Ogawa, M., Takada, N., Noda, S., Takahashi, M., Matsutani, M., Kageyama, D. & Ebihara, H., Jul 1 2023, In: Journal of Parasitology. 109, 4, p. 340-348 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Trombiculidae 100%
  • Acari 93%
  • Leptotrombidium 89%
  • scrub typhus 88%
  • Orientia tsutsugamushi 87%

• Growth, Pathogenesis, and Serological Characteristics of the Japanese Encephalitis Virus Genotype IV Recent Strain 19CxBa-83-Cv

  Tajima, S., Maeki, T., Nakayama, E., Faizah, A. N., Kobayashi, D., Isawa, H., Maekawa, Y., Bendryman, S. S., Mulyatno, K. C., Rohmah, E. A., Mori, Y., Sawabe, K., Ebihara, H. & Lim, C. K., Jan 2023, In: Viruses. 15, 1, 239.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Japanese Encephalitis Virus 100%
  • Genotype 51%
  • Growth 36%
  • Indonesia 33%
  • Serum 26%

• Identification of imp dehydrogenase as a potential target for anti-mpox virus agents

  Hishiki, T., Morita, T., Akazawa, D., Ohashi, H., Park, E. S., Kataoka, M., Mifune, J., Shionoya, K., Tsuchimoto, K., Ojima, S., Azam, A. H., Nakajima, S., Kawahara, M., Yoshikawa, T., Shimojima, M., Kiga, K., Maeda, K., Suzuki, T., Ebihara, H., Takahashi, Y., & 1 othersWatashi, K., Aug 2023, In: Microbiology Spectrum. 11, 4

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Monkeypox virus 100%
  • virus 55%
  • Oxidoreductases 52%
  • IMP Dehydrogenase 45%
  • IMP dehydrogenase 45%

• Immunocompetent hamsters as a model for orthobunyavirus-induced neuroinvasion and neuropathology

  Groseth, A., Gardner, D., Meade-White, K., Amler, S. & Ebihara, H., May 2023, In: PLoS Neglected Tropical Diseases. 17, 5, e0011355.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Orthobunyavirus 100%
  • Bunyamwera virus 90%
  • Neuropathology 71%
  • Cricetinae 64%
  • animal 38%

• Inactivation of replication-competent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on common surfaces by disinfectants

  Pope, Z. C., Weisend, C. M., Shah, A., Ebihara, H. & Rizza, S. A., Mar 26 2023, In: Infection Control and Hospital Epidemiology. 44, 3, p. 504-506 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Severe Acute Respiratory Syndrome 100%
  • Coronavirus 97%
  • Disinfectants 95%
  • Disinfection 30%
  • Touch 26%

• Interferon-independent processes constrain measles virus cell-to-cell spread in primary human airway epithelial cells

  Durnell, L. A., Hippee, C. E., Cattaneo, R., Bartlett, J. A., Singh, B. K. & Sinn, P. L., Oct 2023, In: Microbiology Spectrum. 11, 5

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • measles 100%
  • Measles morbillivirus 97%
  • Measles virus 85%
  • interferons 76%
  • virus 65%

• Markerless bacterial artificial chromosome manipulation method by red proteins of phage λ mediated homologous recombination utilizing fluorescent proteins for both positive and counter selection

  Yoshikawa, T., Misu, M., Kurosu, T., Takamatsu, Y., Sugimoto, S., Shimojima, M., Ebihara, H. & Saijo, M., Aug 2023, In: Heliyon. 9, 8, e18983.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Bacterial Artificial Chromosomes 100%
  • Homologous Recombination 80%
  • Bacteriophages 71%
  • Genetic Recombination 34%
  • Plasmids 29%

• Multiomics single timepoint measurements to predict severe COVID-19 – Authors' reply

  Garapati, K., Byeon, S. K., Walsh, J. R., Jenkinson, G., Cattaneo, R., O'Horo, J. C., Badley, A. D. & Pandey, A., Feb 2023, In: The Lancet Digital Health. 5, 2, p. e57

  Research output: Contribution to journal › Letter › peer-review

  Open Access

• Nationwide Laboratory Surveillance of Progressive Multifocal Leukoencephalopathy in Japan: Fiscal Years 2011–2020

  Nakamichi, K., Miura, Y., Shimokawa, T., Takahashi, K., Suzuki, T., Funata, N., Harada, M., Mori, K., Sanjo, N., Yukitake, M., Takahashi, K., Hamaguchi, T., Izaki, S., Oji, S., Nakahara, J., Ae, R., Kosami, K., Nukuzuma, S., Nakamura, Y., Nomura, K., & 6 othersKishida, S., Mizusawa, H., Yamada, M., Takao, M., Ebihara, H. & Saijo, M., Apr 2023, In: Viruses. 15, 4, 968.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Progressive Multifocal Leukoencephalopathy 100%
  • JC Virus 67%
  • Japan 60%
  • Cerebrospinal Fluid 35%
  • Polymerase Chain Reaction 14%

• Neoadjuvant systemic oncolytic vesicular stomatitis virus is safe and may enhance long-term survivorship in dogs with naturally occurring osteosarcoma

  Makielski, K. M., Sarver, A. L., Henson, M. S., Stuebner, K. M., Borgatti, A., Suksanpaisan, L., Preusser, C., Tabaran, A. F., Cornax, I., O'Sullivan, M. G., Chehadeh, A., Groschen, D., Bergsrud, K., Pracht, S., Winter, A., Mills, L. J., Schwabenlander, M. D., Wolfe, M., Farrar, M. A., Cutter, G. R., & 4 othersKoopmeiners, J. S., Russell, S. J., Modiano, J. F. & Naik, S., Dec 19 2023, In: Molecular Therapy Oncolytics. 31, 100736.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Vesicular Stomatitis 100%
  • Survivorship 94%
  • Osteosarcoma 81%
  • Dogs 56%
  • Viruses 52%

• Oncolytic viruses: Narcissistic or altruistic arsonists?

  Kendall, L. & Vile, R. G., Jun 15 2023, In: Molecular Therapy Oncolytics. 29, p. 42-43 2 p.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access

• Polycytidine tract deletion from microRNA-detargeted oncolytic Mengovirus optimizes the therapeutic index in a murine multiple myeloma model

  Penza, V., Maroun, J. W., Nace, R. A., Schulze, A. J. & Russell, S. J., Mar 16 2023, In: Molecular Therapy Oncolytics. 28, p. 15-30 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mengovirus 100%
  • Therapeutic Index 71%
  • Multiple Myeloma 57%
  • MicroRNAs 49%
  • Tropism 23%

• Potential Anti-Mpox Virus Activity of Atovaquone, Mefloquine, and Molnupiravir, and Their Potential Use as Treatments

  Akazawa, D., Ohashi, H., Hishiki, T., Morita, T., Iwanami, S., Kim, K. S., Jeong, Y. D., Park, E. S., Kataoka, M., Shionoya, K., Mifune, J., Tsuchimoto, K., Ojima, S., Azam, A. H., Nakajima, S., Park, H., Yoshikawa, T., Shimojima, M., Kiga, K., Iwami, S., & 5 othersMaeda, K., Suzuki, T., Ebihara, H., Takahashi, Y. & Watashi, K., Sep 1 2023, In: Journal of Infectious Diseases. 228, 5, p. 591-603 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Atovaquone 100%
  • Mefloquine 87%
  • ST-246 60%
  • Viruses 41%
  • Pharmaceutical Preparations 25%

• Protocol of Tecopox study: a multicentre, open-label, double-arm trial to evaluate the efficacy and safety of oral tecovirimat therapy for patients with smallpox or monkeypox

  Suzuki, T., Saito, S., Tsuzuki, S., Ashida, S., Takakusaki, M., Yoshikawa, T., Shimojima, M., Ebihara, H., Ohmagari, N. & Morioka, S., Aug 1 2023, In: BMJ open. 13, 8, e069550.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • ST-246 100%
  • Monkeypox 87%
  • Smallpox 70%
  • Multicenter Studies 44%
  • Safety 30%

• Rapid whole genome sequencing methods for RNA viruses

  Misu, M., Yoshikawa, T., Sugimoto, S., Takamatsu, Y., Kurosu, T., Ouji, Y., Yoshikawa, M., Shimojima, M., Ebihara, H. & Saijo, M., 2023, In: Frontiers in Microbiology. 14, 1137086.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Whole Genome Sequencing 100%
  • Viral Genome 97%
  • RNA Viruses 97%
  • High-Throughput Nucleotide Sequencing 54%
  • RNA 33%

• SARS-CoV-2 spike protein-mediated cardiomyocyte fusion may contribute to increased arrhythmic risk in COVID-19

  Clemens, D. J., Ye, D., Zhou, W., John Kim, C. S., Pease, D. R., Navaratnarajah, C. K., Barkhymer, A., Tester, D. J., Nelson, T. J., Cattaneo, R., Schneider, J. W. & Ackerman, M. J., Mar 2023, In: PloS one. 18, 3 March, e0282151.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • SARS Virus 100%
  • Induced Pluripotent Stem Cells 76%
  • Cardiac Myocytes 63%
  • Giant Cells 43%
  • Furin 38%

• Saturation time of exposure interval for cross-neutralization response to SARS-CoV-2: Implications for vaccine dose interval

  Miyamoto, S., Kuroda, Y., Kanno, T., Ueno, A., Shiwa-Sudo, N., Iwata-Yoshikawa, N., Sakai, Y., Nagata, N., Arashiro, T., Ainai, A., Moriyama, S., Kishida, N., Watanabe, S., Nojima, K., Seki, Y., Mizukami, T., Hasegawa, H., Ebihara, H., Fukushi, S., Takahashi, Y., & 2 othersMaeda, K. & Suzuki, T., May 19 2023, In: iScience. 26, 5, 106694.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • SARS Virus 100%
  • Vaccines 50%
  • Infections 32%
  • Serum 12%
  • Epidemics 11%

• Subtype of SCLC Is an Intrinsic and Persistent Feature Through Systemic Treatment

  Lo, Y. C., Rivera-Concepcion, J., Vasmatzis, G., Aubry, M. C. & Leventakos, K., Sep 2023, In: JTO Clinical and Research Reports. 4, 9, 100561.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Drug Therapy 100%
  • Therapeutics 55%
  • Artifacts 54%
  • Transcription Factors 42%
  • Immunohistochemistry 39%

• The combination of levodopa with levodopa-metabolizing enzyme inhibitors prevents severe fever with thrombocytopenia syndrome virus infection in vitro more effectively than single levodopa

  Ogawa, M., Murae, M., Mizukami, T., Gemba, R., Irie, T., Shimojima, M., Ebihara, H., Noguchi, K. & Fukasawa, M., May 2023, In: Journal of Infection and Chemotherapy. 29, 5, p. 549-553 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Enzyme Inhibitors 100%
  • Levodopa 97%
  • Thrombocytopenia 82%
  • Fever 65%
  • Virus Diseases 64%

• Therapeutic applications of viral vectors

  Lowenstein, P., Stone, D., David, A., Melcher, A., Vile, R., Thomas, C., Bataille, D. & Castro, M., May 31 2023, Genetically Engineered Viruses: Development and Applications. CRC Press, p. 215-254 40 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Trap and ambush therapy using sequential primary and tumor escape-selective oncolytic viruses

  Webb, M. J., Kottke, T., Kendall, B. L., Swanson, J., Uzendu, C., Tonne, J., Thompson, J., Metko, M., Moore, M., Borad, M., Roberts, L., Diaz, R. M., Olin, M., Borgatti, A. & Vile, R., Jun 15 2023, In: Molecular Therapy Oncolytics. 29, p. 129-142 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Permethrin 100%
  • Oncolytic Viruses 94%
  • Tumor Escape 91%
  • Oncolytic Virotherapy 42%
  • Cold-Shock Response 36%

• Treatment with tecovirimat of the first two cases of monkeypox in Japan

  Inada, M., Saito, S., Tsuzuki, S., Okumura, N., Sato, L., Kamegai, K., Sanada, M., Komatsubara, M., Shimojima, M., Ebihara, H., Kasuya, F., Nagashima, M., Sadamasu, K., Yamamoto, K., Ujiie, M., Morioka, S. & Ohmagari, N., Apr 2023, In: Journal of Infection and Chemotherapy. 29, 4, p. 418-421 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • ST-246 100%
  • Monkeypox 87%
  • Japan 42%
  • Coitus 19%
  • North America 18%