Mayo Clinic

Projects

Projects per year 1973 2021

• 45 Active
• 777 Not started
• 1574 Finished

Projects per year

Search results

• Research project

  ANGIOTENSIN-II BLOCKADE IN MITRAL REGURGITATION

  Sarano, M. E.

  Project: Research project

  • Mitral Valve Insufficiency 100%
  • Ventricular Remodeling 21%
  • Angiotensins 21%
  • Ramipril 17%
  • Placebos 16%

• Complex Antithrombotic Therapy in Older Veterans: GI Risk and Preference

  Abraham, N. S.

  National Institutes of Health

  Project: Research project

  • Veterans 100%
  • Elderly 54%
  • Patient Preference 17%
  • Self-Management 17%
  • Medicare 16%

• IMPACT OF SEX-RELATED HORMONE LEVELS AND GENETIC VARIATION ON ALCOHOL USE DISORDERS AND RELATED PHENOTYPES IN MALES AND FEMALES

  Karpyak, V. M. & Winham, S. J.

  National Institute on Alcohol Abuse and Alcoholism

  Project: Research project

  • Gonadal Steroid Hormones 100%
  • Alcoholism 87%
  • Genetic Variation 63%
  • Sex Characteristics 60%
  • Phenotype 36%

• CAF, A COACTIVATOR OF FOS, AND BREAST CANCER

  Leof, E. B.

  National Cancer Institute

  Project: Research project

  • Myofibroblasts 100%
  • Transforming Growth Factor beta1 87%
  • Thromboplastin 72%
  • Breast Neoplasms 55%
  • Transforming Growth Factor beta 39%

• Pathogenic effects of plasma ApoE on CNS function and Alzheimer's disease

  Liu, C.

  National Institute on Aging

  Project: Research project

  • Apolipoproteins E 100%
  • Central Nervous System Diseases 74%
  • Alzheimer Disease 69%
  • Apolipoprotein E4 56%
  • Brain 36%

• Cerebral Microbleeds in the Aging Population

  Graff-Radford, J.

  National Institute on Aging

  Project: Research project

  • Positron-Emission Tomography 100%
  • Neuroimaging 97%
  • Organized Financing 84%
  • Cerebral Hemorrhage 77%
  • Amyloid 67%

• Dementia and Heart Failure in the Community

  Roger, V. L.

  National Institute on Aging

  Project: Research project

  • Heart Failure 100%
  • Dementia 80%
  • Electronic Health Records 22%
  • Data Science 20%
  • Patient Acceptance of Health Care 17%

• TTR and C9ORF72 in ALS and related disorders

  Van Blitterswijk, M.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Chromosomes, Human, Pair 9 100%
  • Prealbumin 93%
  • Open Reading Frames 72%
  • Amyotrophic Lateral Sclerosis 57%
  • Frontotemporal Dementia With Motor Neuron Disease 43%

• A Randomized Cross-Over Trial Evaluating Automated Insulin Delivery Technologies on Glycemic Outcomes and Quality of Life in Older Adults with Type 1 Diabetes

  Kudva, Y. C.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • Cross-Over Studies 100%
  • Type 1 Diabetes Mellitus 85%
  • Suspensions 77%
  • Technology 71%
  • Insulin 69%

• Turning K-12 Environmental STEM Education InSciEd Out

  Pierret, C. K.

  NIH Office of the Director

  Project: Research project

  • mathematics 100%
  • engineering 88%
  • education 49%
  • medication 38%
  • Environmental toxicology 26%

• Advanced Heart Failure: Epidemiology and Outcomes

  Dunlay, S. M.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Heart Failure 100%
  • Epidemiology 76%
  • Palliative Care 34%
  • Phenotype 28%
  • Population 23%

• Vasopeptidases and Beta Amyloid Accumulation

  Younkin, S. G.

  Project: Research project

  • Endothelin-Converting Enzymes 100%
  • Amyloid beta-Peptides 91%
  • Neprilysin 86%
  • Vasopeptidase Inhibitors 57%
  • Peptidyl-Dipeptidase A 54%

• Can Consumers and Audiologists Detect Ear Disease Prior to Hearing Aid Use?

  Zapala, D. A., Kinney, L., Kinney, L. & Zapala, D. A.

  National Institute on Deafness and Other Communication Disorders

  Project: Research project

  • Ear Diseases 100%
  • Audiologists 94%
  • Hearing Aids 83%
  • United States Food and Drug Administration 21%
  • Hearing 19%

• Role of SerpinA3 in the response of glioblastoma to cerebrospinal fluid

  Guerrero Cazares, H.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Glioblastoma 100%
  • Cerebrospinal Fluid 83%
  • Brain Neoplasms 34%
  • Lateral Ventricles 27%
  • Neoplastic Stem Cells 26%

• CTRA Software Solution for Fracture Risk Assessment of Axial Skeleton

  Yaszemski, M. J.

  National Institute on Aging

  Project: Research project

  • Skeleton 100%
  • Tomography 88%
  • Software 78%
  • Risk Assessment 59%
  • Neoplasm Metastasis 33%

• Gene discovery in PSP by transcriptome, neuropathology and sequence analysis

  Ertekin-Taner, N. & Kinney, L.

  Project: Research project

  • Progressive Supranuclear Palsy 100%
  • Neuropathology 24%
  • Genome-Wide Association Study 22%
  • Brain 12%
  • Neurodegenerative Diseases 9%

• Migration of Human Neural Stem Cells In Vitro and In Vivo

  Quinones-Hinojosa, A.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Neural Stem Cells 100%
  • Lateral Ventricles 80%
  • Astrocytes 44%
  • In Vitro Techniques 36%
  • Ependyma 35%

• Drug repurposing study for tobacco dependence treatment using zebrafish

  Klee, E. W. & Kinney, L.

  National Institute on Drug Abuse

  Project: Research project

  • Tobacco Use Disorder 100%
  • Zebrafish 95%
  • Drug Repositioning 95%
  • Varenicline 36%
  • Tobacco 34%

• Structural biology of DNA damage response in chromatin

  Mer, G.

  National Institute of General Medical Sciences

  Project: Research project

  • Chromatin 100%
  • DNA Damage 98%
  • Post Translational Protein Processing 81%
  • Nucleosomes 61%
  • Homologous Recombination 59%

• Preclinical testing of iPSC derived retinal pigment epithelium to treat macular degeneration

  Marmorstein, A. D.

  National Eye Institute

  Project: Research project

  • Retinal Pigment Epithelium 100%
  • Induced Pluripotent Stem Cells 90%
  • Macular Degeneration 83%
  • Transplantation 23%
  • Cell Line 22%

• Chemically produced neural progenitors as a delivery vehicle for anti-glioma therapy

  Quinones-Hinojosa, A.

  National Cancer Institute

  Project: Research project

  • Glioma 100%
  • Tropism 47%
  • Bone Morphogenetic Protein 4 47%
  • Neural Stem Cells 44%
  • Stem Cells 38%

• Does the gut have a sense of touch?

  Beyder, A.

  National Center for Complementary and Integrative Health

  Project: Research project

  • Enterochromaffin Cells 100%
  • Touch 66%
  • Irritable Bowel Syndrome 50%
  • Serotonin 37%
  • Gastrointestinal Diseases 23%

• cGAS-STING Pathway Targeting Replicative Adenoviruses with CD46 Tropism and AFP Promoter Conditional Replication Restriction for the Treatment of Hepatocellular Carcinoma

  Nagalo, M.

  National Cancer Institute

  Project: Research project

  • Adenoviridae 100%
  • Tropism 96%
  • Hepatocellular Carcinoma 88%
  • Liver Neoplasms 76%
  • Oncolytic Virotherapy 39%

• Single non-integrating RNA vector for gene editing and reprogramming of Fanconi anemia fibroblasts

  Devaux, P.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Induced Pluripotent Stem Cells 100%
  • Fanconi Anemia 94%
  • Gene Editing 75%
  • Fibroblasts 56%
  • Measles virus 45%

• Regulation of RLIM Activity by Phosphorylation

  Johnsen, S. & Kinney, L.

  National Cancer Institute

  Project: Research project

  • Phosphorylation 100%
  • Neoplasm Metastasis 56%
  • Lim Kinases 50%
  • Neoplasms 49%
  • LIM Domain Proteins 49%

• Enhancing Treatment Response by Leveraging STAT5-OLIG2 signaling in GBM

  Tran, N.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Glioblastoma 100%
  • Glioma 57%
  • epidermal growth factor receptor VIII 56%
  • Temozolomide 32%
  • Stem Cells 32%

• International Conference on Advances in Quantitative Laryngology, Voice and Speech Research (AQL)

  Lott, D. G.

  National Institute on Deafness and Other Communication Disorders

  Project: Research project

  • continuity 100%
  • website 96%
  • student 73%
  • planning 71%
  • pathology 57%

• Genetic Biomarkers for Risk of CLL Progression among high-count MBLs

  Slager, S. L.

  National Cancer Institute

  Project: Research project

  • B-Cell Chronic Lymphocytic Leukemia 100%
  • Lymphocytosis 98%
  • B-Lymphocytes 86%
  • Biomarkers 48%
  • Asymptomatic Diseases 48%

• Neuronal antigen surveillance and autoimmunity in CNS demyelinating disease

  Howe, C. L.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Demyelinating Diseases 100%
  • T-Lymphocytes 88%
  • Central Nervous System Diseases 83%
  • Axons 83%
  • Multiple Sclerosis 75%

• Beta1-selective blockade for prevention of postmenopausal bone loss: A randomized controlled trial

  Khosla, S.

  National Institute on Aging

  Project: Research project

  • Atenolol 100%
  • Postmenopausal Osteoporosis 84%
  • Osteoporosis 80%
  • Bone and Bones 61%
  • Randomized Controlled Trials 38%

• SURGICAL PLANNING WITH REAL TIME MOTION CORRECTED FMRI

  Jack, C. R. J.

  National Cancer Institute

  Project: Research project

  • Magnetic Resonance Imaging 100%
  • Head 73%
  • Brain Mapping 68%
  • Brain Neoplasms 46%
  • Neurosurgical Procedures 33%

• Airway Structural Cells and Corticosteroid Resistance in Asthma

  Britt, R. J.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Adrenal Cortex Hormones 100%
  • Smooth Muscle 85%
  • Asthma 72%
  • Airway Remodeling 28%
  • Inflammation 25%

• Optimization of antigen preparations from Coccidioides for diagnostic testing

  Grys, T.

  National Institute of Allergy and Infectious Diseases

  Project: Research project

  • Coccidioides 100%
  • Mycelium 94%
  • Antigens 70%
  • Coccidioidomycosis 67%
  • Chitinases 50%

• IMPLEMENTATION OF DMOL &COSMO PROGRAM ON CRAY T3D: MOLEC STRUCT

  Sine, S. M.

  National Center for Research Resources

  Project: Research project

  • Molecular Dynamics Simulation 100%
  • Nicotinic Receptors 99%
  • Drug Discovery 92%
  • Organized Financing 53%
  • Workflow 49%

• Localizing value and underlying mechanisms of low frequency EEG for focal epilepsy

  Lundstrom, B.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Electroencephalography 100%
  • Partial Epilepsy 78%
  • Microelectrodes 27%
  • Biostatistics 24%
  • Biomarkers 21%

• What is N? Towards operationalizing neurodegeneration in Alzheimer's and related dementias

  Graff-Radford, J., Mielke, M. M. & Vemuri, P. D.

  National Institute on Aging

  Project: Research project

  • Alzheimer Disease 100%
  • Cognitive Dysfunction 77%
  • Cerebrovascular Disorders 73%
  • Dementia 71%
  • Amyloid 67%

• Memory T cell development and survival in T cell responses of older individuals

  Goronzy, J.

  National Institute of Allergy and Infectious Diseases

  Project: Research project

  • T-Lymphocytes 99%
  • Vaccination 46%
  • T-Lymphoid Precursor Cells 27%
  • Apoptosis 23%
  • Chickenpox 23%

• Impact of Airway Inflammation on Mitochondria

  Prakash, Y. S. & Sieck, G. C.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Endoplasmic Reticulum Stress 100%
  • Reactive Oxygen Species 82%
  • Mitochondria 79%
  • Mitochondrial Size 55%
  • Inflammation 45%

• Frontotemporal dementia and related disorders: transcriptomic profiling, biomarker discovery, and mechanistic insight

  Gendron, T. D. & Van Blitterswijk, M.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Frontotemporal Dementia 100%
  • Frontotemporal Dementia With Motor Neuron Disease 61%
  • Biomarkers 52%
  • DNA-Binding Proteins 44%
  • Blood Specimen Collection 36%

• Role of Spp1 on microglia and Alzheimer's disease

  Kang, S.

  National Institute on Aging

  Project: Research project

  • Tauopathies 100%
  • Amyloidosis 98%
  • Osteopontin 87%
  • Microglia 82%
  • Gliosis 52%

• Artificial Intelligence-Based Approaches for Renal Structure Characterization in Computed Tomography Images

  Kline, T.

  Project: Research project

  • Imaging techniques 100%
  • Biomarkers 40%
  • Biopsy 21%
  • Image acquisition 18%
  • Pathology 18%

• Non-invasive imaging of progenitor cell fate in the ischemic myocardium

  Rodriguez-Porcel, M. G. & Kinney, L.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Oxidants 100%
  • Myocardium 71%
  • Reporter Genes 57%
  • Stem Cells 49%
  • Antioxidants 28%

• Role of NOX4 and redox environment in Autosomal Dominant Polycystic Kidney Disease

  Irazabal Mira, M.

  Project: Research project

  • NADPH Oxidase 4 100%
  • Cyclic AMP-Dependent Protein Kinases 46%
  • Up-Regulation 32%
  • Oxidation-Reduction 30%
  • Disease Progression 30%

• Effects of senescence to Alzheimer's disease pathology

  Baker, D. J.

  National Institute on Aging

  Project: Research project

  • Neurodegenerative Diseases 100%
  • Pathology 68%
  • Alzheimer Disease 66%
  • Preliminary Data 31%
  • Drive 29%

• Accelerating Dissemination of Implantable Neurotechnology for Clinical Research

  Worrell, G. A.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Equipment and Supplies 100%
  • Research Personnel 83%
  • Movement Disorders 53%
  • Software Validation 42%
  • Adaptive Clinical Trials 42%

• Yale-Mayo FDA Center for Excellence in Regulatory Science and Innovation

  Shah, N. D.

  U.S. Food and Drug Administration

  Project: Research project

  • decision making 100%
  • innovation 46%
  • product evaluation 29%
  • educational institutions 27%
  • medical equipment 27%

• California National Primate Research Center

  Cattaneo, R.

  National Institutes of Health

  Project: Research project

  • Primates 100%
  • immunology 39%
  • research programs 35%
  • infrastructure 35%
  • bioacoustics 23%

• Protecting the Confidentiality of Participants in Studies of Alzheimer's Disease and Related Dementias by Replacing Face Imagery in MRI

  Schwarz, C.

  Project: Research project

  • Magnetic resonance 100%
  • Biomarkers 59%
  • Imaging techniques 48%
  • Face recognition 45%
  • Transplants 22%

• Resolving the cancer relevance of predisposition gene mutations

  Couch, F. J.

  Project: Research project

  • Breast Neoplasms 100%
  • Genes 53%
  • Genetic Testing 37%
  • BRCA2 Gene 34%
  • Penetrance 27%

• CORE--STAINING AND RECONSTRUCTION OF NEURONS AND THEIR PROCESSES IN 3-DIMENSIONS

  Salisbury, J. L.

  National Center for Research Resources

  Project: Research project

  • Protein 100%
  • Organism 93%
  • breast 87%
  • tumors 79%
  • Cells 58%