Mayo Clinic

Projects

Projects per year 1973 2021

• 45 Active
• 777 Not started
• 1574 Finished

Projects per year

Search results

• Studies of mRNA translational regulations in erythropoiesis

  Hu, W.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Erythropoiesis 100%
  • Formal Social Control 73%
  • Erythroid Cells 70%
  • Messenger RNA 40%
  • Ribosomes 29%

• Microsystems for Shaping Stem Cell Fate Selections

  Revzin, A.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • stem cells 100%
  • growth factors 47%
  • microfluidic technology 41%
  • cells 31%
  • induced pluripotent stem cells 25%

• Predictors of Venous Thromboembolism: A Multicenter Prospective Cohort Study

  Park, M. (. S.

  Project: Research project

  • Venous Thromboembolism 100%
  • Wounds and Injuries 16%
  • Genotype 12%
  • factor V Leiden 11%
  • Prothrombin 9%

• Simultaneously boosting both humoral and cellular immunity following vaccination

  Sun, J. & Sun, J.

  National Institutes of Health, National Institute on Aging

  Project: Research project

  • Human Influenza 100%
  • Humoral Immunity 89%
  • Cellular Immunity 83%
  • Vaccination 69%
  • Cytotoxic T-Lymphocytes 45%

• Development of High Throughput Screening Assays (RMI)

  Rosenfeld, S. & Kinney, L.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • High-Throughput Screening Assays 100%
  • Glioma 69%
  • Kinesin 38%
  • Cell Movement 37%
  • Mitosis 29%

• Targeting macrophage Bcl6 to enhance innate resistance to influenza

  Sun, J.

  National Institute of Allergy and Infectious Diseases

  Project: Research project

  • Orthomyxoviridae 100%
  • Human Influenza 74%
  • Macrophages 47%
  • Virus Diseases 33%
  • Pandemics 19%

• The pathophysiological role of the immunoproteasome in atherosclerosis

  Herrmann, J.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Atherosclerosis 100%
  • Apolipoproteins E 35%
  • High Fat Diet 22%
  • Interferon-gamma 19%
  • Molecular Mechanisms of Pharmacological Action 17%

• DC-ASGPR AS A NOVEL TARGET FOR CONTROLLING GVHD AND ALLOGRAFT REJECTION

  Oh, S. & Kinney, L.

  National Institute of Allergy and Infectious Diseases

  Project: Research project

  • Graft vs Host Disease 100%
  • Dendritic Cells 90%
  • Allografts 79%
  • Isoantigens 36%
  • Immunosuppression 35%

• Sleep Apnea and Hypertrophic Cardiomyopathy - Implications for Arrhythmia and Sudden Death

  Somers, V.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Hypertrophic Cardiomyopathy 100%
  • Sleep Apnea Syndromes 81%
  • Sudden Death 74%
  • Cardiac Arrhythmias 63%
  • Obstructive Sleep Apnea 62%

• HL-Inorganic Nitrite to Enhance Benefits from Exercise Training in Heart Failure with preserved Ejection Fraction

  Borlaug, B. A.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Nitrites 100%
  • Exercise 73%
  • Heart Failure 72%
  • Quality of Life 15%
  • Cyclic GMP 10%

• Targeted chemotherapy delivery and capture

  Oklu, R.

  National Institute of Biomedical Imaging and Bioengineering

  Project: Research project

  • Drug Therapy 100%
  • Pharmaceutical Preparations 75%
  • Drug-Eluting Stents 71%
  • Drug Liberation 59%
  • Drug-Related Side Effects and Adverse Reactions 56%

• FASEB SRC on Polycystic Kidney Disease: Challenges, differing viewpoints and ways forward

  Torres, V.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • polycystic kidney diseases 100%
  • autosomal dominant polycystic kidney disease 16%
  • cilia 16%
  • researchers 11%
  • kidneys 10%

• Epidermal growth factor receptor signaling in glioma

  Uhm, J.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • ErbB Receptors 100%
  • Glioma 96%
  • Receptor Protein-Tyrosine Kinases 20%
  • erbB-1 Genes 12%
  • Mentors 11%

• Cellular senescence in aging and age-related disease.

  Van Deursen, J., Bram, R. J. & Van Deursen, J.

  National Institute on Aging

  Project: Research project

  • Healthy Aging 8%
  • Phenotype 8%
  • Preliminary Data 7%
  • Mortality 7%
  • Cell Cycle Checkpoints 6%

• Epigenetic Regulation in Primary Sclerosing Cholangitis

  Huebert, R. C.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • Sclerosing Cholangitis 100%
  • Enhancer of Zeste Homolog 2 Protein 91%
  • Hepatic Stellate Cells 73%
  • Acetylation 62%
  • Epigenomics 61%

• Harnessing the Electronic Health Record to Predict Risk of Cardiovascular Disease

  Bielinski, S. J.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Electronic Health Records 100%
  • Cardiovascular Diseases 69%
  • Precision Medicine 22%
  • Natural Language Processing 10%
  • Deep Learning 9%

• Cardiac Magnetic Resonance Elastography: Imaging Heart Failure Pathophysiology

  Araoz, P. A., Kinney, L. & Kinney, L.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • elasticity imaging techniques 100%
  • heart failure 81%
  • pathophysiology 60%
  • image analysis 40%
  • myocardial infarction 14%

• Genetic Markers of Long-Term Mumps Vaccine Immunity

  Kennedy, R. B.

  National Institute of Allergy and Infectious Diseases

  Project: Research project

  • Mumps Vaccine 100%
  • Genetic Markers 52%
  • Immunity 44%
  • Mumps 38%
  • Single Nucleotide Polymorphism 33%

• Novel Peptide Therapeutics for Hypertension

  Burnett, J. C. J.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Atrial Natriuretic Factor 100%
  • Hypertension 90%
  • Blood Pressure 66%
  • Peptides 65%
  • Aldosterone 62%

• Treatment of arterial aneurysms using an injectable biomaterial

  Oklu, R.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Biocompatible Materials 100%
  • Aneurysm 96%
  • Injections 51%
  • Rupture 21%
  • Therapeutics 15%

• Mechanistic Effects of Health Coaching to reduce COPD Hospitalizations

  Benzo, R. P.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Mentoring 100%
  • National Heart, Lung, and Blood Institute (U.S.) 93%
  • Chronic Obstructive Pulmonary Disease 70%
  • Hospitalization 55%
  • Health 38%

• Lipoxin-Mediated Inflammatory Resolution in Newborn Hyperoxic Lung Injury

  Britt, R. J. & Kinney, L.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Lipoxins 100%
  • Lung Injury 56%
  • Bronchopulmonary Dysplasia 48%
  • Newborn Infant 42%
  • Aspirin 28%

• Statistics and Data Center for the Alliance for Clinical Trials in Oncology

  Mandrekar, S. J. & Kinney, L.

  National Cancer Institute

  Project: Research project

  • Data Management 100%
  • Statistics 68%
  • Clinical Trials 32%
  • Manuscripts 19%
  • Adaptive Clinical Trials 17%

• Radiomic phenotypes of breast parenchyma and association with breast cancer risk and detection

  Vachon, C. M.

  National Cancer Institute

  Project: Research project

  • Breast 100%
  • Breast Neoplasms 92%
  • Breast Density 89%
  • Phenotype 85%
  • Mammography 55%

• Predictors of change in prosocial attitudes during medical education

  Phelan, S. M.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • school climate 100%
  • shortage 76%
  • Healthcare Providers 66%
  • medicine 60%
  • contact 58%

• Molecular Discriminators in Benign Breast Tissue for Future Risk of ER positive a

  Degnim, A. C.

  National Cancer Institute

  Project: Research project

  • Breast 100%
  • Breast Neoplasms 89%
  • Mutation 31%
  • Biopsy 25%
  • Neoplasms 22%

• PQ6: Role of Cellular Senescence in Late Effects of Childhood Cancer Therapy

  Bram, R. J.

  National Cancer Institute

  Project: Research project

  • cell senescence 100%
  • cancer therapy 86%
  • childhood 77%
  • neoplasms 59%
  • therapeutics 39%

• NRSA Training Core

  Windebank, A. J.

  National Center for Advancing Translational Sciences

  Project: Research project

  • learning 100%
  • biomedical researchers 88%
  • Improvements in health 82%
  • school research 77%
  • career 75%

• ANALYSES OF METABOLIC ACTIVATION/INACTIVATION OF SELECT CHEMICAL CARCINOGENS

  Pitot, H. C.

  Project: Research project

  • carcinogens 100%
  • ethyl carbamate 88%
  • DNA adducts 75%
  • precocenes 59%
  • epoxides 52%

• Vaccine Synergy through Synchronous Delivery

  Barry, M. A.

  National Institute of Allergy and Infectious Diseases

  Project: Research project

  • vaccines 100%
  • immunization 69%
  • mucosal immunity 59%
  • vaccination 51%
  • animals 35%

• Understanding measles vaccine failure (and success) in Southern India

  Kennedy, R. B. & Kennedy, R. B.

  National Institute of Allergy and Infectious Diseases

  Project: Research project

  • Measles Vaccine 100%
  • Measles 85%
  • India 60%
  • Vaccines 33%
  • Disease Outbreaks 33%

• Mechanism and role of aberrant AR activity in castration-resistant prostate cancer

  Huang, H.

  National Cancer Institute

  Project: Research project

  • Castration 100%
  • Androgen Receptors 99%
  • Prostatic Neoplasms 76%
  • MDV 3100 60%
  • abiraterone 17%

• Ex vivo gene therapy for metabolic liver disease

  Hickey, R.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • Metabolic Diseases 100%
  • Hepatocytes 98%
  • Genetic Therapy 88%
  • Liver Diseases 78%
  • Liver Failure 21%

• Administrative Core

  Petrucelli, L. & Petrucelli, L.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Amyotrophic Lateral Sclerosis 100%
  • Biomarkers 48%
  • Dementia 42%
  • Cell Nucleus Active Transport 21%
  • RNA 16%

• Molecular pathobiology of soluble TREM2 in Alzheimer's disease.

  Bu, G. D.

  National Institute on Aging

  Project: Research project

  • Myeloid Cells 100%
  • Alzheimer disease type 2 86%
  • Genome-Wide Association Study 37%
  • Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy 33%
  • Cerebrospinal Fluid 31%

• Endocytic Trafficking of ADCs in GBM cancer stem-like cells

  Sarkaria, J. N.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • ABT-414 100%
  • Neoplastic Stem Cells 64%
  • Glioblastoma 64%
  • Immunoconjugates 26%
  • Recycling 16%

• Transcriptomic Signatures of Influenza Vaccine Responses

  Kennedy, R. B. & Poland, G. A.

  National Institute of Allergy and Infectious Diseases

  Project: Research project

  • Influenza Vaccines 100%
  • Helper-Inducer T-Lymphocytes 87%
  • MF59 oil emulsion 69%
  • Vaccines 63%
  • Human Influenza 58%

• Efficacy of self-management of sedative therapy by ventilated ICU patients

  Chlan, L.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Self-Management 100%
  • Hypnotics and Sedatives 98%
  • Intensive Care Units 75%
  • Artificial Respiration 32%
  • Nurses 29%

• Reducing Sedative Exposure in Ventilated ICU Patients

  Chlan, L. & Kinney, L.

  National Institute of Nursing Research

  Project: Research project

  • Hypnotics and Sedatives 100%
  • Intensive Care Units 82%
  • Anxiety 59%
  • Artificial Respiration 47%
  • Music 36%

• The Subproteome in Age-related Macular Degeneration

  Olsen, T. & Kinney, L.

  National Institute on Aging

  Project: Research project

  • Macular Degeneration 100%
  • Proteomics 17%
  • Epidemiologic Studies 15%
  • Lipofuscin 12%
  • Proteins 10%

• Imaging Functionally Distinct Eosinophil Subtypes Within Tissue Biopsies Using Gene Expression Profiling and an In Situ Hybridization Approach based on a Concurrent Multiple RNA Targeting Strategy

  Jacobsen, E.

  National Institute of Allergy and Infectious Diseases

  Project: Research project

  • Eosinophils 100%
  • Gene Expression Profiling 72%
  • In Situ Hybridization 67%
  • RNA 50%
  • Biopsy 46%

• COGNITIVE IMPAIRMENT IN PARKINSON'S DISEASE--ROLE OF ALPHA-SYNUCLEIN

  Pandey, A.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Proteomics 60%
  • Biomarkers 45%
  • Synucleins 28%
  • Mass Spectrometry 24%
  • Post Translational Protein Processing 20%

• BIOMARKER DISCOVERY AND VALIDATION IN PSP

  Pandey, A.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Progressive Supranuclear Palsy 100%
  • Biomarkers 43%
  • Cerebrospinal Fluid 39%
  • Globus Pallidus 15%
  • Proteomics 12%

• Fourier Transform Orbitrap Fusion Lumos Tribrid Mass Spectrometer with ETD

  Pandey, A.

  NIH Office of the Director

  Project: Research project

  • Fourier Analysis 100%
  • Research Personnel 58%
  • Post Translational Protein Processing 58%
  • Proteomics 51%
  • Competitive Bidding 51%

• Actions of Endoxifen on the Skeleton

  Gingery, A., Kinney, L. & Kinney, L.

  National Institute of Arthritis and Musculoskeletal and Skin Diseases

  Project: Research project

  • Tamoxifen 100%
  • Antiresorptive 87%
  • Anabolic Agent 81%
  • Raloxifene 80%
  • Estrogen 52%

• Neurogenesis in the Human Brain

  Quinones-Hinojosa, A.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Lateral Ventricles 100%
  • Neurogenesis 62%
  • Olfactory Bulb 51%
  • Brain 36%
  • Neural Stem Cells 25%

• 2/4: Leveraging EHR-linked biobanks for deep phenotyping, polygenic risk score modeling, and outcomes analysis in psychiatric disorders

  Biernacka, J. M.

  National Institute of Mental Health

  Project: Research project

  • Electronic Health Records 100%
  • Mental Disorders 66%
  • Major Depressive Disorder 47%
  • Psychiatry 42%
  • Substance-Related Disorders 30%

• Evaluation of germline mutations associated with risk of nephrolithiasis

  Haley, W. E.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • Nephrolithiasis 100%
  • Kidney Calculi 93%
  • Germ-Line Mutation 63%
  • Causality 35%
  • Mutation 16%

• Quantifying Multiscale Competitive Landscapes of Clonal Diversity in Glioblastoma

  Tran, N., Hu, L. S. & Swanson, K.

  National Cancer Institute

  Project: Research project

  • Glioblastoma 100%
  • Biopsy 51%
  • Machine Learning 47%
  • Neoplasms 31%
  • Recurrence 24%

• Fecal Incontinence Treatment Study (FIT Study)

  Bharucha, A. E. & Bharucha, A. E.

  Project: Research project

  • Fecal Incontinence 100%
  • National Institute of Diabetes and Digestive and Kidney Diseases (U.S.) 24%
  • Research Personnel 20%
  • Therapeutics 15%
  • Health Care Outcome Assessment 9%