Mayo Clinic

Projects

Projects per year 1973 2021

• 45 Active
• 777 Not started
• 1574 Finished

Projects per year

Search results

• Vaccine Synergy through Synchronous Delivery

  Barry, M. A.

  National Institute of Allergy and Infectious Diseases

  Project: Research project

  • vaccines 100%
  • immunization 69%
  • mucosal immunity 59%
  • vaccination 51%
  • animals 35%

• Understanding measles vaccine failure (and success) in Southern India

  Kennedy, R. B. & Kennedy, R. B.

  National Institute of Allergy and Infectious Diseases

  Project: Research project

  • Measles Vaccine 100%
  • Measles 85%
  • India 60%
  • Vaccines 33%
  • Disease Outbreaks 33%

• Mechanism and role of aberrant AR activity in castration-resistant prostate cancer

  Huang, H.

  National Cancer Institute

  Project: Research project

  • Castration 100%
  • Androgen Receptors 99%
  • Prostatic Neoplasms 76%
  • MDV 3100 60%
  • abiraterone 17%

• Ex vivo gene therapy for metabolic liver disease

  Hickey, R.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • Metabolic Diseases 100%
  • Hepatocytes 98%
  • Genetic Therapy 88%
  • Liver Diseases 78%
  • Liver Failure 21%

• Precision Medicine by Targeting Cell Adhesion in Melanoma

  Meves, A.

  National Cancer Institute

  Project: Research project

  • Melanoma 100%
  • Precision Medicine 99%
  • Cell Adhesion 90%
  • Sentinel Lymph Node 25%
  • Integrins 13%

• Quantitative Ultrasound Imaging Biomarkers of Crohn's Disease

  Chen, S. D., Chen, S. D. & Bruining, D. H.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • Crohn Disease 100%
  • Ultrasonography 66%
  • Fibrosis 62%
  • Biomarkers 53%
  • Comb and Wattles 48%

• TRAINING IN TRANSLATIONAL RESEARCH--BENCH TO BEDSIDE

  Maher III, J., Maher III, J., Kinney, L., Kinney, L. & Kinney, L.

  National Institute of General Medical Sciences

  Project: Research project

  • student 100%
  • minority 92%
  • medicine 70%
  • career 64%
  • Students 64%

• Role of viral mitophagosomes in driving sex differences in myocarditis

  Fairweather, D.

  Project: Research project

  • Myocarditis 100%
  • Enterovirus 91%
  • Mitochondria 29%
  • Heart 23%
  • Heart Failure 19%

• NCI, National Clinical Trials Network Lead Academic Participating Site (LAPS) UG1

  Boughey, J. C. & Alberts, S. R.

  National Cancer Institute

  Project: Research project

  • Clinical Trials 100%
  • Research Personnel 22%
  • Organizations 20%
  • Neoplasms 10%
  • Physicians 10%

• Regulatory Action of Protease Activated Receptor 1 in Myelin Production

  Scarisbrick, I. A.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Myelin Sheath 100%
  • PAR-1 Receptor 75%
  • Oligodendrocyte Precursor Cells 44%
  • Multiple Sclerosis 37%
  • Cuprizone 26%

• Uncovering RNA signatures of C9ORF72-linked ALS and related disorders

  Van Blitterswijk, M.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Chromosomes, Human, Pair 9 100%
  • Open Reading Frames 72%
  • Amyotrophic Lateral Sclerosis 44%
  • RNA Sequence Analysis 35%
  • RNA 34%

• Mechanotransduction and YAP/TAZ Signaling in Pulmonary Arterial Hypertension

  Tschumperlin, D. J. & Tschumperlin, D. J.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Pulmonary Arterial Hypertension 100%
  • Bone Morphogenetic Proteins 88%
  • Prostaglandins 58%
  • Smooth Muscle Myocytes 54%
  • Pulmonary Artery 47%

• ICAM-1 GENE EXPRESSION IN MALIGNANT GLIAL TUMORS

  Rosenfeld, S. & Rosenfeld, S.

  National Institutes of Health, National Institute of Neurological Disorders and Stroke

  Project: Research project

  • glioma 100%
  • neuroglia 83%
  • cell biology 80%
  • Glioma 79%
  • molecular biology 73%

• Phase 3 stem cell transplant for light chain amyloidosis

  Gertz, M., Gertz, M. & Kinney, L.

  National Cancer Institute

  Project: Research project

  • Amyloidosis 100%
  • Light 66%
  • Stem Cells 64%
  • Transplants 54%
  • Amyloid 41%

• Mechanisms of Processivity in Molecular Motors

  Rosenfeld, S. & Kinney, L.

  National Institute of General Medical Sciences

  Project: Research project

  • Kinesin 100%
  • Neck 64%
  • Head 41%
  • myosin VI 24%
  • Myosin Type V 23%

• Microfabricated Biosensor Platform for Monitoring of Cell Metabolism

  Revzin, A. & Kinney, L.

  National Institute of Biomedical Imaging and Bioengineering

  Project: Research project

  • biosensors 100%
  • hepatocytes 69%
  • monitoring 52%
  • cell culture 51%
  • metabolism 46%

• Regulating pulmonary inflammation by type I IFN signaling in neutrophils during i

  Sun, J. & Kinney, L.

  National Institute of Allergy and Infectious Diseases

  Project: Research project

  • Eragrostis 100%
  • Interleukin-10 74%
  • Interleukin-27 72%
  • Neutrophils 60%
  • Pneumonia 57%

• Designing a Microenvironment Niche for Liver-Specific Differentiation of hESCs

  Revzin, A., Kinney, L. & Kinney, L.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • niches 100%
  • stem cells 98%
  • liver 77%
  • hepatocytes 72%
  • embryonic stem cells 68%

• Cell-Penetrating Aptamers Targeting Sub-Cellular Compartments

  Maher III, J.

  National Institute of General Medical Sciences

  Project: Research project

  • Nucleic Acid 100%
  • Enzyme Activity 39%
  • Toxic 17%
  • Lipid 16%
  • Cation 13%

• ADPKD: Understanding mechanisms, Discovering treatments.

  Li, X., Kinney, L. & Kinney, L.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • Epithelial Cells 45%
  • Cysts 27%
  • TRPP Cation Channels 22%
  • Tumor Necrosis Factor-alpha 21%
  • Apoptosis 19%

• Analyzing and Interpreting PRO-CTCAE with CTCAE and Other Clinical Data to Characterize Drug Tolerability

  Dueck, A. & Dueck, A.

  National Cancer Institute

  Project: Research project

  • Patient Reported Outcome Measures 100%
  • Terminology 88%
  • Clinical Trials 38%
  • Pharmaceutical Preparations 30%
  • Research Personnel 27%

• AMP-Kinase as a target for neuroprotection in AD

  Trushina, E. D.

  National Institute on Aging

  Project: Research project

  • AMP-Activated Protein Kinases 100%
  • Adenylate Kinase 60%
  • Neuroprotection 46%
  • Astrocytes 14%
  • Organelle Biogenesis 13%

• The Ohio State University Pancreatic Disorders Network (OSU-PDN)

  Topazian, M.

  Project: Research project

  • pancreatitis 100%
  • pancreatic diseases 91%
  • pancreatic neoplasms 83%
  • diabetes 54%
  • translational medical research 53%

• Microsystems and modeling approach to glioma migration and metastasis

  Rosenfeld, S., Kinney, L. & Kinney, L.

  National Cancer Institute

  Project: Research project

  • Glioma 100%
  • Neoplasm Metastasis 46%
  • Mechanics 33%
  • Brain 31%
  • Brain Neoplasms 30%

• Modeling and microsystems approach to glioma invasion

  Rosenfeld, S., Kinney, L., Kinney, L. & Rosenfeld, S.

  National Cancer Institute

  Project: Research project

  • Glioma 100%
  • Brain 54%
  • Hydrogels 33%
  • Glioblastoma 31%
  • Adhesiveness 21%

• Center for Modeling Tumor Cell Migration Mechanics: Administrative Core

  Rosenfeld, S.

  National Cancer Institute

  Project: Research project

  • Mechanics 100%
  • Cell Movement 78%
  • Neoplasms 31%
  • Tumor Microenvironment 28%
  • Reverse Genetics 18%

• Small Molecule Discovery for Particulate Guanylyl Cyclase Receptor B Enhancers

  Burnett, J. C. J. & Sangaralingham, S. J.

  National Institute on Aging

  Project: Research project

  • atrial natriuretic factor receptor B 100%
  • Guanylate Cyclase 77%
  • Fibrosis 46%
  • Heart Failure 45%
  • Small Molecule Libraries 29%

• Drug Eluting Embolization Coils for Improved Treatment of Intracranial Aneurysms

  Kadirvel, R. D. & Kadirvel, R. D.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Intracranial Aneurysm 100%
  • Aneurysm 97%
  • genipin 51%
  • Pharmaceutical Preparations 38%
  • Safety 32%

• Quantifying Multiscale Competitive Landscapes of Clonal Diversity in Glioblastoma

  Tran, N., Hu, L. S. & Swanson, K.

  National Cancer Institute

  Project: Research project

  • Glioblastoma 100%
  • Biopsy 51%
  • Machine Learning 47%
  • Neoplasms 31%
  • Recurrence 24%

• Fecal Incontinence Treatment Study (FIT Study)

  Bharucha, A. E. & Bharucha, A. E.

  Project: Research project

  • Fecal Incontinence 100%
  • National Institute of Diabetes and Digestive and Kidney Diseases (U.S.) 24%
  • Research Personnel 20%
  • Therapeutics 15%
  • Health Care Outcome Assessment 9%

• Automated Glucose Regulation to improve Diabetes Control and Outcomes for Pregnant Women with Type 1 Diabetes and Fetus

  Kudva, Y. C. & Kudva, Y. C.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • Artificial Pancreas 100%
  • Type 1 Diabetes Mellitus 54%
  • Pregnant Women 47%
  • Fetus 40%
  • Glucose 36%

• Universal positive allosteric modulators of CCK1R without intrinsic agonist activity for the treatment of obesity

  Miller, L. J.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • CHO Cells 100%
  • Obesity 58%
  • cholecystokinin 58 55%
  • Cholecystokinin Receptors 39%
  • Small Molecule Libraries 39%

• Enhanced, EHR-facilitated Cancer Symptom Control (E2C2) Pragmatic Clinical Trial

  Cheville, A. L.

  National Cancer Institute

  Project: Research project

  • Pragmatic Clinical Trials 100%
  • Touch 50%
  • Patient Reported Outcome Measures 41%
  • Neoplasms 38%
  • Self-Management 26%

• Increasing Adherence to Pulmonary Rehabilitation after COPD-related Hospitalizations

  Benzo, R. P.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Chronic Obstructive Pulmonary Disease 100%
  • Rehabilitation 89%
  • Hospitalization 76%
  • Lung 65%
  • Telerehabilitation 22%

• Advances in Phase-Contrast MR Angiography

  Pipe, J. & Kinney, L.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • flow velocity 100%
  • shear stress 95%
  • method 71%
  • shear flow 61%
  • data acquisition 50%

• Step down of asthma biologics in real-world practice settings

  Rank, M. A.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Asthma 100%
  • Biological Products 99%
  • Omalizumab 48%
  • reslizumab 36%
  • mepolizumab 33%

• Astrocytic function in DBS for essential tremor

  Chang, S.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Essential Tremor 100%
  • Tremor 89%
  • Astrocytes 77%
  • Adenosine 41%
  • Optogenetics 36%

• Obesity-induced mesenchymal stem cell senescence

  Lerman, L. O.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • Mesenchymal Stem Cells 78%
  • Obesity 59%
  • Research Subjects 20%
  • Phenotype 20%
  • Extracellular Vesicles 16%

• Cardiorenal Fibrosis: Biology and Therapeutics

  Sangaralingham, S. J.

  Project: Research project

  • C-Type Natriuretic Peptide 100%
  • Fibrosis 83%
  • Kidney 54%
  • Guanylate Cyclase 42%
  • atrial natriuretic factor receptor B 37%

• Engineering an HIV-resistant immune system for HIV cure

  Fadel, H.

  National Institute of Allergy and Infectious Diseases

  Project: Research project

  • HIV-1 100%
  • Immune System 77%
  • HIV 74%
  • Hematopoietic Stem Cells 30%
  • Genetic Therapy 21%

• Alcoholic Hepatitis Clinical and Translational Network Late Phase Clinical Trials and Observational Studies 5/9

  Kamath, P. S., Shah, V. & Shah, V.

  National Institute on Alcohol Abuse and Alcoholism

  Project: Research project

  • Alcoholic Hepatitis 100%
  • Observational Studies 46%
  • Clinical Studies 40%
  • Clinical Trials 39%
  • Granulocyte Colony-Stimulating Factor 16%

• Phenotypes of Aging & Senescence

  LeBrasseur, N. K.

  National Institute on Aging

  Project: Research project

  • cell senescence 100%
  • senescence (aging) 94%
  • phenotype 61%
  • clinical trials 54%
  • cells 27%

• Hypertensive pregnancy disorders and future coronary artery disease

  Garovic, V. D.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Coronary Artery Disease 100%
  • Pregnancy 71%
  • Pre-Eclampsia 39%
  • Reproductive History 32%
  • Epidemiology 20%

• IMMUNOGENICITY OF A XENOGENEIC BIOARTIFICAL LIVER

  Nyberg, S. & Kinney, L.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • Artificial Liver 100%
  • Liver 32%
  • Acute Liver Failure 21%
  • Hepatocytes 15%
  • Liver Failure 10%

• Clinical evaluation of combination oncolytic viro-immunotherapy for solid tumors

  Adjei, A. & Adjei, A.

  National Cancer Institute

  Project: Research project

  • Immunotherapy 100%
  • Vesicular Stomatitis 61%
  • Oncolytic Virotherapy 58%
  • Non-Small Cell Lung Carcinoma 51%
  • Neoplasms 43%

• Predicting Breast Cancer Risk after Benign Percutaneous Biopsy

  Degnim, A. C., Sherman, M. E. & Sherman, M. E.

  National Cancer Institute

  Project: Research project

  • Breast Diseases 100%
  • Breast Neoplasms 80%
  • Biopsy 70%
  • Breast Density 20%
  • Anatomic Models 16%

• Microsystems for Modeling Neurodevelopmental Disorders

  Revzin, A.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Down Syndrome 100%
  • Neurodevelopmental Disorders 80%
  • Astrocytes 44%
  • Induced Pluripotent Stem Cells 38%
  • Synapses 31%

• Administrative Core

  Petrucelli, L. & Petrucelli, L.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Amyotrophic Lateral Sclerosis 100%
  • Biomarkers 48%
  • Dementia 42%
  • Cell Nucleus Active Transport 21%
  • RNA 16%

• Molecular pathobiology of soluble TREM2 in Alzheimer's disease.

  Bu, G. D.

  National Institute on Aging

  Project: Research project

  • Myeloid Cells 100%
  • Alzheimer disease type 2 86%
  • Genome-Wide Association Study 37%
  • Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy 33%
  • Cerebrospinal Fluid 31%

• Endocytic Trafficking of ADCs in GBM cancer stem-like cells

  Sarkaria, J. N.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • ABT-414 100%
  • Neoplastic Stem Cells 64%
  • Glioblastoma 64%
  • Immunoconjugates 26%
  • Recycling 16%