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A phase II safety and efficacy study of the vascular endothelial growth factor receptor tyrosine kinase inhibitor pazopanib in patients with metastatic urothelial cancer

Pili, R., Qin, R., Flynn, P. J., Picus, J., Millward, M., Ho, W. M., Pitot, H., Tan, W., Miles, K. M., Erlichman, C. & Vaishampayan, U., Dec 1 2013, In : Clinical Genitourinary Cancer. 11, 4, p. 477-483 7 p.

Research output: Contribution to journalArticle

49 Scopus citations

A phase II study of ABT-510 (thrombospondin-1 analog) for the treatment of metastatic melanoma

Markovic, S. N., Suman, V. J., Rao, R. A., Ingle, J. N., Kaur, J. S., Erickson, L. A., Pitot, H. C., Croghan, G. A., McWilliams, R. R., Merchan, J., Kottschade, L. A., Nevala, W. K., Uhl, C. B., Allred, J. & Creagan, E. T., Jun 1 2007, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 30, 3, p. 303-309 7 p.

Research output: Contribution to journalArticle

69 Scopus citations

A phase II study of AZD2171 (cediranib) in the treatment of patients with acute myeloid leukemia or high-risk myelodysplastic syndrome

Mattison, R., Jumonville, A., Flynn, P. J., Moreno-Aspitia, A., Erlichman, C., Laplant, B. & Juckett, M. B., Jul 1 2015, In : Leukemia and Lymphoma. 56, 7, p. 2061-2066 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

A phase II study of gemcitabine in combination with tanespimycin in advanced epithelial ovarian and primary peritoneal carcinoma

Wahner Hendrickson, A. E., Oberg, A. L., Glaser, G., Camoriano, J. K., Peethambaram, P. P., Colon-Otero, G., Erlichman, C., Ivy, S. P., Kaufmann, S. H., Karnitz, L. M. & Haluska, P., Feb 1 2012, In : Gynecologic oncology. 124, 2, p. 210-215 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

A phase II study of paclitaxel plus carboplatin as first-line chemotherapy for women with metastatic breast carcinoma

Perez, E. A., Hillman, D. W., Stella, P. J., Krook, J. E., Hartmann, L. C., Fitch, T. R., Hatfield, A. K., Mailliard, J. A., Nair, S., Kardinal, C. G. & Ingle, J. N., Jan 1 2000, In : Cancer. 88, 1, p. 124-131 8 p.

Research output: Contribution to journalArticle

73 Scopus citations

A phase II study of pazopanib with oral topotecan in patients with metastatic osteosarcoma

van Tine, B. A., Mohindra, N., Milhem, M., Attia, S., Robinson, S. I., Rademaker, A., Okuno, S. H. & Agulnik, M., Oct 1 2018, In : Annals of oncology : official journal of the European Society for Medical Oncology. 29, p. viii579

Research output: Contribution to journalArticle

Open Access

A phase II study to evaluate the combination of fludarabine, mitoxantrone and dexamethasone (FMD) in patients with follicular lymphoma

Crawley, C. R., Foran, J. M., Gupta, R. K., Rohatiner, A. Z. S., Summers, K., Matthews, J., Micallef, I. N. M., Radford, J. A., Johnson, S. A., Johnson, P. W., Sweetenham, J. W. & Lister, T. A., Sep 23 2000, In : Annals of Oncology. 11, 7, p. 861-865 5 p.

Research output: Contribution to journalArticle

46 Scopus citations

A phase II trial of 17-allylamino-17-demethoxygeldanamycin in patients with hormone-refractory metastatic prostate cancer

Heath, E. I., Gaskins, M., Pitot, H. C., Pili, R., Tan, W., Marschke, R., Liu, G., Hillman, D., Sarkar, F., Sheng, S., Erlichman, C. & Ivy, P., Sep 2005, In : Clinical Prostate Cancer. 4, 2, p. 138-141 4 p.

Research output: Contribution to journalArticle

48 Scopus citations

A Phase II trial of 17-allylamino-17-demethoxygeldanamycin in patients with hormone-refractory metastatic prostate cancer

Heath, E. I., Hillman, D. W., Vaishampayan, U., Sheng, S., Sarkar, F., Harper, F., Gaskins, M., Pitot, H. C., Tan, W., Ivy, S. P., Pili, R., Carducci, M. A., Erlichman, C. & Liu, G., Dec 1 2008, In : Clinical Cancer Research. 14, 23, p. 7940-7946 7 p.

Research output: Contribution to journalArticle

137 Scopus citations

A phase II trial of a combination of pemetrexed and gemcitabine in patients with metastatic breast cancer: An NCCTG study

Ma, C. X., Steen, P., Rowland, K. M., Niedringhaus, R. D., Fitch, T. R., Kugler, J. W., Hillman, D. W., Perez, E. A., Ingle, J. N. & Adjei, A. A., Feb 2006, In : Annals of Oncology. 17, 2, p. 226-231 6 p.

Research output: Contribution to journalArticle

17 Scopus citations

A phase II trial of capecitabine in combination with the farnesyltransferase inhibitor tipifarnib in patients with anthracycline-treated and taxane-resistant metastatic breast cancer: An Eastern Cooperative Oncology Group Study (E1103)

Li, T., Guo, M., Gradishar, W. J., Sparano, J. A., Perez, E. A., Wang, M. & Sledge, G. W., Jul 2012, In : Breast Cancer Research and Treatment. 134, 1, p. 345-352 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

A phase II trial of docetaxel and carboplatin administered every 2 weeks as preoperative therapy for stage II or III breast cancer: NCCTG study N0338

Roy, V., Pockaj, B. A., Allred, J. B., Apsey, H., Northfelt, D. W., Nikcevich, D., Mattar, B. & Perez, E. A., Dec 1 2013, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 36, 6, p. 540-544 5 p.

Research output: Contribution to journalArticle

11 Scopus citations

A phase II trial of docetaxel and carboplatin as first-line chemotherapy for metastatic breast cancer: NCCTG study N9932

Perez, E. A., Suman, V. J., Fitch, T. R., Mailliard, J. A., Ingle, J. N., Cole, J. T., Veeder, M. H., Flynn, P. J., Walsh, D. J. & Addo, F. K., Sep 2005, In : Oncology. 69, 2, p. 117-121 5 p.

Research output: Contribution to journalArticle

15 Scopus citations

A phase II trial of edatrexate, vinblastine, adriamycin, cisplastin, and filgrastim (EVAC/G-CSF) in patients with non-small-cell carcinoma of the lungs: A North Central Cancer Treatment Group trial

Colon-Otero, G., Niedringhaus, R. D., Hillman, S. H., Geyer, S., Sloan, J., Krook, J. E., Windschitl, H. E., Marks, R. S., Wiesenfeld, M., Tschetter, L. K. & Jett, J. J., Dec 22 2001, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 24, 6, p. 551-555 5 p.

Research output: Contribution to journalArticle

14 Scopus citations

A phase II trial of green tea in the treatment of patients with androgen independent metastatic prostate carcinoma

Jatoi, A., Ellison, N., Burch, P. A., Sloan, J. A., Dakhil, S. R., Novotny, P., Tan, W., Fitch, T. R., Rowland, K. M., Young, C. Y. F. & Flynn, P. J., Mar 15 2003, In : Cancer. 97, 6, p. 1442-1446 5 p.

Research output: Contribution to journalArticle

208 Scopus citations

A Phase II trial of the oral mTOR inhibitor everolimus in relapsed Hodgkin lymphoma

Johnston, P. B., Inwards, D. J., Colgan, J. P., Laplant, B. R., Kabat, B. F., Habermann, T. M., Micallef, I. N., Porrata, L. F., Ansell, S. M., Reeder, C. B., Roy, V. & Witzig, T. E., May 1 2010, In : American journal of hematology. 85, 5, p. 320-324 5 p.

Research output: Contribution to journalArticle

178 Scopus citations

A phase II trial of tipifarnib in myelofibrosis: Primary, post-polycythemia vera and post-essential thrombocythemia

Mesa, R. A., Camoriano, J. K., Geyer, S. M., Wu, W. D., Kaufmann, S. H., Rivera, C. E., Erlichman, C., Wright, J., Pardanani, A., Lasho, T., Finke, C., Li, C. Y. & Tefferi, A., Sep 2007, In : Leukemia. 21, 9, p. 1964-1970 7 p.

Research output: Contribution to journalArticle

32 Scopus citations

A phase II trial of trastuzumab plus weekly ixabepilone and carboplatin in patients with HER2-positive metastatic breast cancer: An Eastern Cooperative Oncology Group Trial

Moulder, S., Li, H., Wang, M., Gradishar, W. J., Perez, E. A., Sparano, J. A., Pins, M., Yang, X. & Sledge, G. W., Feb 1 2010, In : Breast Cancer Research and Treatment. 119, 3, p. 663-671 9 p.

Research output: Contribution to journalArticle

36 Scopus citations

A phase I open-label, dose-escalation, multi-institutional trial of injection with an E1B-attenuated adenovirus, ONYX-015, into the peritumoral region of recurrent malignant gliomas, in the adjuvant setting

Chiocca, E. A., Abbed, K. M., Tatter, S., Louis, D. N., Hochberg, F. H., Barker, F., Kracher, J., Grossman, S. A., Fisher, J. D., Carson, K., Rosenblum, M., Mikkelsen, T., Olson, J., Markert, J., Rosenfeld, S., Nabors, L. B., Brem, S., Phuphanich, S., Freeman, S., Kaplan, R. & 1 others, Zwiebel, J., Nov 2004, In : Molecular Therapy. 10, 5, p. 958-966 9 p.

Research output: Contribution to journalArticle

270 Scopus citations

A phase I study of the safety and tolerability of VLX600, an Iron Chelator, in patients with refractory advanced solid tumors

Mody, K., Mansfield, A., Vemireddy, L., Nygren, P., Gulbo, J. & Borad, M. J., Jan 1 2018, (Accepted/In press) In : Investigational New Drugs.

Research output: Contribution to journalArticle

3 Scopus citations

A phase i study of vorinostat in combination with bortezomib in patients with advanced malignancies

Schelman, W. R., Traynor, A. M., Holen, K. D., Kolesar, J. M., Attia, S., Hoang, T., Eickhoff, J., Jiang, Z., Alberti, D., Marnocha, R., Reid, J. M., Ames, M. M., McGovern, R. M., Espinoza-Delgado, I., Wright, J. J., Wilding, G. & Bailey, H. H., Dec 1 2013, In : Investigational New Drugs. 31, 6, p. 1539-1546 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

A Phase I Study to Assess the Safety and Pharmacokinetics of Single-agent Lorvotuzumab Mertansine (IMGN901) in Patients with Relapsed and/or Refractory CD–56-positive Multiple Myeloma

Ailawadhi, S., Kelly, K. R., Vescio, R. A., Jagannath, S., Wolf, J., Gharibo, M., Sher, T., Bojanini, L., Kirby, M. & Chanan-Khan, A., Jan 2019, In : Clinical Lymphoma, Myeloma and Leukemia. 19, 1, p. 29-34 6 p.

Research output: Contribution to journalArticle

10 Scopus citations

A phase I trial of ad.hIFN-β gene therapy for glioma

Chiocca, E. A., Smith, K. M., McKinney, B., Palmer, C. A., Rosenfeld, S., Lillehei, K., Hamilton, A., DeMasters, B. K., Judy, K. & Kirn, D., Mar 2008, In : Molecular Therapy. 16, 3, p. 618-626 9 p.

Research output: Contribution to journalArticle

84 Scopus citations
25 Scopus citations

A pilot investigation of a multidisciplinary quality of life intervention for men with biochemical recurrence of prostate cancer

Ames, S. C., Tan, W. W., Ames, G. E., Stone, R. L., Rizzo, T. D., Crook, J. E., Williams, C. R., Werch, C. E., Clark, M. M. & Rummans, T. A., Apr 1 2011, In : Psycho-Oncology. 20, 4, p. 435-440 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

A pilot program in collaboration with African American churches successfully increases awareness of the importance of cancer research and participation in cancer translational research studies among African Americans

Colon-Otero, G., Albertie, M., Lesperance, M., Weis, J. A., Coles, A., Smith, N., Mills, L., Woodward, T., Aspitia, A. M., Vishnu, P., Willis, F., Isley, A., Fonseca, R., Vachon, C. & Rajkumar, S. V., Jun 1 2012, In : Journal of Cancer Education. 27, 2, p. 294-298 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

A pilot randomized clinical trial assessing the effect of cricoid pressure on risk of aspiration

Bohman, J. K., Kashyap, R., Lee, A., He, Z., Soundar, S., Bolling, L. L. & Kor, D. J., 2016, (Accepted/In press) In : Clinical Respiratory Journal.

Research output: Contribution to journalArticle

3 Scopus citations

A pilot study of in vivo identification of pancreatic cystic neoplasms with needle-based confocal laser endomicroscopy under endosonographic guidance

Konda, V. J. A., Meining, A., Jamil, L. H., Giovannini, M., Hwang, J. H., Wallace, M. B., Chang, K. J., Siddiqui, U. D., Hart, J., Lo, S. K., Saunders, M. D., Aslanian, H. R., Wroblewski, K. & Waxman, I., Dec 25 2013, In : Endoscopy. 45, 12, p. 1006-1013 8 p.

Research output: Contribution to journalArticle

130 Scopus citations

A pilot study to assess the use of protein a immunoadsorption for chronic dilated cardiomyopathy

Cooper, L. T., Belohlavek, M., Korinek, J., Yoshifuku, S., Sengupta, P. P., Burgstaler, E. A. & Winters, J. L., Aug 31 2007, In : Journal of Clinical Apheresis. 22, 4, p. 210-214 5 p.

Research output: Contribution to journalArticle

27 Scopus citations

A pooled analysis of the cardiac events in the trastuzumab adjuvant trials

de Azambuja, E., Ponde, N., Procter, M., Rastogi, P., Cecchini, R. S., Lambertini, M., Ballman, K., Aspitia, A. M., Zardavas, D., Roca, L., Gelber, R. D., Piccart-Gebhart, M. & Suter, T., Jan 1 2020, In : Breast Cancer Research and Treatment. 179, 1, p. 161-171 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

Apoptosis and hepatobiliary disease

Patel, T. & Gores, G. J., Jun 1995, In : Hepatology. 21, 6, p. 1725-1741 17 p.

Research output: Contribution to journalArticle

242 Scopus citations

Apoptosis and the liver: A mechanism of disease, growth regulation, and carcinogenesis

Patel, T., Steer, C. J. & Gores, G. J., Sep 7 1999, In : Hepatology. 30, 3, p. 811-815 5 p.

Research output: Contribution to journalArticle

45 Scopus citations

Apoptosis in hepatic pathophysiology

Patel, T., Jan 1 2000, In : Clinics in liver disease. 4, 2, p. 295-317 23 p.

Research output: Contribution to journalArticle

34 Scopus citations

Apoptosis is inhibited early in the dysplasia-carcinoma sequence of Barrett esophagus

Katada, N., Hinder, R. A., Smyrk, T. C., Hirabayashi, N., Perdikis, G., Lund, R. J., Woodward, T. & Klingler, P. J., Jan 1 1997, In : Archives of Surgery. 132, 7, p. 728-733 6 p.

Research output: Contribution to journalArticle

87 Scopus citations

Apoptotic cell death of human interstitial cells of Cajal

Gibbons, S. J., De Giorgio, R., Faussone Pellegrini, M. S., Garrity-Park, M. M., Miller, S. M., Schmalz, P. F., Young-Fadok, T. M., Larson, D. W., Dozois, E. J., Camilleri, M., Stanghellini, V., Szurszewski, J. H. & Farrugia, G., Jan 1 2009, In : Neurogastroenterology and Motility. 21, 1, p. 85-93 9 p.

Research output: Contribution to journalArticle

50 Scopus citations

A population-based case-control study of CARD15 and other risk factors in Crohn's disease and ulcerative colitis

Brant, S. R., Wang, M. H., Rawsthorne, P., Sargent, M., Datta, L. W., Nouvet, F., Shugart, Y. Y. & Bernstein, C. N., Feb 1 2007, In : American Journal of Gastroenterology. 102, 2, p. 313-323 11 p.

Research output: Contribution to journalArticle

52 Scopus citations

A population of gut epithelial enterochromaffin cells is mechanosensitive and requires Piezo2 to convert force into serotonin release

Alcaino, C., Knutson, K. R., Treichel, A. J., Yildiz, G., Strege, P. R., Linden, D. R., Li, J. H., Leiter, A. B., Szurszewski, J. H., Farrugia, G. & Beyder, A., Aug 7 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 32, p. E7632-E7641

Research output: Contribution to journalArticle

25 Scopus citations

A posttranslational modification of the mitotic kinesin Eg5 that enhances its mechanochemical coupling and alters its mitotic function

Muretta, J. M., Reddy, B. J. N., Scarabelli, G., Thompson, A. F., Jariwala, S., Major, J., Venere, M., Rich, J. N., Willard, B., Thomas, D. D., Stumpff, J., Grant, B. J., Gross, S. P. & Rosenfeld, S. S., Feb 20 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 8, p. E1779-E1788

Research output: Contribution to journalArticle

7 Scopus citations
2 Scopus citations

Application of a conversion factor to estimate the adenoma detection rate from the polyp detection rate

Francis, D. L., Rodriguez-Correa, D. T., Buchner, A., Harewood, G. C. & Wallace, M., Mar 1 2011, In : Gastrointestinal endoscopy. 73, 3, p. 493-497 5 p.

Research output: Contribution to journalArticle

84 Scopus citations

Application of adaptive design and decision making to a phase II trial of a phosphodiesterase inhibitor for the treatment of intermittent claudication

Lewis, R. J., Connor, J. T., Teerlink, J. R., Murphy, J. R., Cooper, L. T., Hiatt, W. R. & Brass, E. P., May 25 2011, In : Trials. 12, 134.

Research output: Contribution to journalArticle

5 Scopus citations

Application of family-based association testing to assess the genotype-phenotype association involved in complex traits using single-nucleotide polymorphisms

Wang, M. H., Guo, M. & Shugart, Y. Y., Dec 30 2005, In : BMC genetics. 6, SUPPL.1, S68.

Research output: Contribution to journalArticle

1 Scopus citations

Applications of confocal endomicroscopy in colon polyps

Wallace, M. B., Oct 1 2013, In : Video Journal and Encyclopedia of GI Endoscopy. 1, 2, p. 301-302 2 p.

Research output: Contribution to journalArticle

Applying extracellular vesicles based therapeutics in clinical trials - An ISEV position paper

Lener, T., Gimona, M., Aigner, L., Börger, V., Buzas, E., Camussi, G., Chaput, N., Chatterjee, D., Court, F. A., del Portillo, H. A., O'Driscoll, L., Fais, S., Falcon-Perez, J. M., Felderhoff-Mueser, U., Fraile, L., Gho, Y. S., Görgens, A., Gupta, R. C., Hendrix, A., Hermann, D. M. & 36 others, Hill, A. F., Hochberg, F., Horn, P. A., de Kleijn, D., Kordelas, L., Kramer, B. W., Krämer-Albers, E. M., Laner-Plamberger, S., Laitinen, S., Leonardi, T., Lorenowicz, M. J., Lim, S. K., Lötvall, J., Maguire, C. A., Marcilla, A., Nazarenko, I., Ochiya, T., Patel, T., Pedersen, S., Pocsfalvi, G., Pluchino, S., Quesenberry, P., Reischl, I. G., Rivera, F. J., Sanzenbacher, R., Schallmoser, K., Slaper-Cortenbach, I., Strunk, D., Tonn, T., Vader, P., van Balkom, B. W. M., Wauben, M., El Andaloussi, S., Théry, C., Rohde, E. & Giebel, B., 2015, In : Journal of Extracellular Vesicles. 4, 1, 30087.

Research output: Contribution to journalArticle

392 Scopus citations

Appreciating the broad clinical features of SMAD4 mutation carriers: A multicenter chart review

Wain, K. E., Ellingson, M. S., McDonald, J., Gammon, A., Roberts, M., Pichurin, P., Winship, I., Riegert-Johnson, D. L., Weitzel, J. N. & Lindor, N. M., Aug 2014, In : Genetics in Medicine. 16, 8, p. 588-593 6 p.

Research output: Contribution to journalArticle

28 Scopus citations

Appropriately testing patients with intermediate risk for coronary artery disease: How well are we doing?

Alsaad, A. A. & Shapiro, B. P., May 5 2018, (Accepted/In press) In : Evidence-Based Medicine.

Research output: Contribution to journalArticle

A practical guide to defining high-risk myeloma for clinical trials, patient counseling and choice of therapy

Stewart, A. K., Bergsagel, P. L., Greipp, P. R., Dispenzieri, A., Gertz, M. A., Hayman, S. R., Kumar, S., Lacy, M. Q., Lust, J. A., Russell, S. J., Witzig, T. E., Zeldenrust, S. R., Dingli, D., Reeder, C. B., Roy, V., Kyle, R. A., Rajkumar, S. V. & Fonseca, R., Mar 2007, In : Leukemia. 21, 3, p. 529-534 6 p.

Research output: Contribution to journalArticle

166 Scopus citations

A preliminary study of serum concentrations of soluble epidermal growth factor receptor (sErbB1), gonadotropins, and steroid hormones in healthy men and women

Baron, A. T., Lafky, J. M., Maihle, N. J., Suman, V. J., Hillman, D. W., Buenafe, M. C., Boardman, C. H., Podratz, K. C. & Perez, E. A., Jan 1 2001, In : Cancer Epidemiology Biomarkers and Prevention. 10, 11, p. 1175-1185 11 p.

Research output: Contribution to journalArticle

28 Scopus citations

Aprepitant Has Mixed Effects on Nausea and Reduces Other Symptoms in Patients With Gastroparesis and Related Disorders

For the, NIDDK Gastroparesis Clinical Research Consortium (GpCRC) & NIDDK Gastroparesis Clinical Research Consortium (GpCRC), Jan 1 2018, In : Gastroenterology. 154, 1, p. 65-76.e11

Research output: Contribution to journalArticle

31 Scopus citations

A proof-of-concept trial of protein kinase C iota inhibition with auranofin for the paclitaxel-induced acute pain syndrome

Jatoi, A., Grudem, M. E., Dockter, T. J., Block, M. S., Villasboas Bisneto, J. J. C. ., Tan, A., Deering, E., Kasi, P. M., Mansfield, A., Botero, J. P., Okuno, S. H., Smith, D. R. & Fields, A. P., Nov 12 2016, (Accepted/In press) In : Supportive Care in Cancer. p. 1-6 6 p.

Research output: Contribution to journalArticle

4 Scopus citations