Research Output

2020

Activation of the GLP-1 receptor by a non-peptidic agonist

Zhao, P., Liang, Y. L., Belousoff, M. J., Deganutti, G., Fletcher, M. M., Willard, F. S., Bell, M. G., Christe, M. E., Sloop, K. W., Inoue, A., Truong, T. T., Clydesdale, L., Furness, S. G. B., Christopoulos, A., Wang, M. W., Miller, L. J., Reynolds, C. A., Danev, R., Sexton, P. M. & Wootten, D., Jan 16 2020, In : Nature. 577, 7790, p. 432-436 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

A Rare EGFR–SEPT14 Fusion in a Patient with Colorectal Adenocarcinoma Responding to Erlotinib

Li, Y., Zhang, H. B., Chen, X., Yang, X., Ye, Y., Bekaii-Saab, T., Zheng, Y. & Zhang, Y., Mar 1 2020, In : Oncologist. 25, 3, p. 203-207 5 p.

Research output: Contribution to journalArticle

Assessment of clinical outcomes with immune checkpoint inhibitor therapy in melanoma patients with CDKN2A and TP53 pathogenic mutations

DeLeon, T. T., Almquist, D. R., Kipp, B. R., Langlais, B. T., Mangold, A., Winters, J. L., Kosiorek, H. E., Joseph, R. W., Dronca, R. S., Block, M. S., McWilliams, R. R., Kottschade, L. A., Rumilla, K. M., Voss, J. S., Seetharam, M., Sekulic, A., Markovic, S. N. & Bryce, A. H., Jan 1 2020, In : PloS one. 15, 3, e0230306.

Research output: Contribution to journalArticle

Open Access

Capsule Retention in Crohn's Disease: A Meta-analysis

Pasha, S. F., Pennazio, M., Rondonotti, E., Wolf, D., Buras, M. R., Albert, J. G., Cohen, S. A., Cotter, J., D'Haens, G., Eliakim, R., Rubin, D. T. & Leighton, J. A., Jan 1 2020, In : Inflammatory bowel diseases. 26, 1, p. 33-42 10 p.

Research output: Contribution to journalReview article

3 Scopus citations

Clinical Outcomes of Portosystemic Shunts on the Outcome of Liver Transplantation

Rodriguez, E. A., Perez, R., Zhang, N., Lim, E. S., Miller, C., Schwartz, M. A., McGirr, A. J., Srinivasan, A., Hewitt, W., Silva, A. C., Rakela, J. & Vargas, H. E., May 1 2020, In : Liver Transplantation. 26, 5, p. 693-701 9 p.

Research output: Contribution to journalArticle

Clinical outcomes with low dose anti-thymocyte globulin in patients undergoing matched unrelated donor allogeneic hematopoietic cell transplantation

Mountjoy, L., Jain, T., Kunze, K. L., Khera, N., Sproat, L. Z., Jennifer, W., McCallen, M., Leis, J. F., Noel, P., Slack, J. L. & Palmer, J., Jan 1 2020, (Accepted/In press) In : Leukemia and Lymphoma.

Research output: Contribution to journalArticle

Correction: Worldwide Network for Blood and Marrow Transplantation (WBMT) perspective: the role of biosimilars in hematopoietic cell transplant: current opportunities and challenges in low- and lower-middle income countries (Bone Marrow Transplantation, (2020), 55, 4, (698-707), 10.1038/s41409-019-0658-2)

Muhsen, I. N., Hashmi, S. K., Niederwieser, D., Kroeger, N., Agrawal, S., Pasquini, M. C., Atsuta, Y., Ballen, K. K., Seber, A., Saber, W., Kharfan-Dabaja, M. A., Rasheed, W., Okamoto, S., Khera, N., Wood, W. A., Koh, M. B. C., Greinix, H., Kodera, Y., Szer, J., Horowitz, M. M. & 2 others, Weisdorf, D. & Aljurf, M., Apr 1 2020, In : Bone Marrow Transplantation. 55, 4, 1 p.

Research output: Contribution to journalComment/debate

Open Access

Critical Appraisal of Published Indirect Comparisons and Network Meta-Analyses of Competing Interventions for Multiple Myeloma

Cope, S., Toor, K., Popoff, E., Fonseca, R., Landgren, O., Mateos, M. V., Weisel, K. & Jansen, J. P., Apr 2020, In : Value in Health. 23, 4, p. 441-450 10 p.

Research output: Contribution to journalArticle

Current imaging techniques for and imaging spectrum of prostate cancer recurrence and metastasis: A pictorial review

Tanaka, T., Yang, M., Froemming, A. T., Bryce, A. H., Inai, R., Kanazawa, S. & Kawashima, A., May 1 2020, In : Radiographics. 40, 3, p. 709-726 18 p.

Research output: Contribution to journalArticle

1 Scopus citations

Deciphering the role of eosinophils in solid organ transplantation

Onyema, O. O., Guo, Y., Hata, A., Kreisel, D., Gelman, A. E., Jacobsen, E. A. & Krupnick, A. S., Apr 1 2020, In : American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 20, 4, p. 924-930 7 p.

Research output: Contribution to journalReview article

Dynamic CD138 surface expression regulates switch between myeloma growth and dissemination

Akhmetzyanova, I., McCarron, M. J., Parekh, S., Chesi, M., Bergsagel, P. L. & Fooksman, D. R., Jan 1 2020, In : Leukemia. 34, 1, p. 245-256 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

EarLy Elimination of Fatty Acids iN hypertriglyceridemia-induced acuTe pancreatitis (ELEFANT trial): Protocol of an open-label, multicenter, adaptive randomized clinical trial

Zádori, N., Gede, N., Antal, J., Szentesi, A., Alizadeh, H., Vincze, Á., Izbéki, F., Papp, M., Czakó, L., Varga, M., de-Madaria, E., Petersen, O. H., Singh, V. P., Mayerle, J., Faluhelyi, N., Miseta, A., Reiber, I. & Hegyi, P., Apr 2020, In : Pancreatology. 20, 3, p. 369-376 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Early post-transplantation factors predict survival outcomes in patients undergoing allogeneic hematopoietic cell transplantation for myelofibrosis

Jain, T., Kunze, K. L., Mountjoy, L., Partain, D. K., Kosiorek, H., Khera, N., Hogan, W. J., Roy, V., Slack, J. L., Noel, P., Fauble, V. D. S., Leis, J. F., Sproat, L., Tefferi, A., Patnaik, M. M., Mesa, R. A. & Palmer, J., Mar 1 2020, In : Blood cancer journal. 10, 3, 36.

Research output: Contribution to journalArticle

Open Access

Expanding the Spectrum of Radiation Necrosis after Stereotactic Radiosurgery (SRS) for Intracranial Metastases from Lung Cancer: A Retrospective Review

Sharma, A., Mountjoy, L. J., Butterfield, R. J., Zhang, N., Ross, H. J., Schild, S. E., Sio, T. T., Daniels, T. B., Paripati, H. R., Mrugala, M. M., Vora, S. A., Patel, N. P., Zimmerman, R. S., Ashman, J. B. & Porter, A. B., Feb 1 2020, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 43, 2, p. 128-132 5 p.

Research output: Contribution to journalArticle

Image Analysis of Eosinophil Peroxidase Immunohistochemistry for Diagnosis of Eosinophilic Esophagitis

Wright, B. L., Doyle, A. D., Shim, K. P., Pai, R. K., Barshow, S. M., Horsley-Silva, J. L., Luo, H., Rank, M. A., Jacobsen, E. A., Katzka, D. A., Kita, H. & Dellon, E. S., Jan 1 2020, (Accepted/In press) In : Digestive diseases and sciences.

Research output: Contribution to journalArticle

Indications for Hematopoietic Cell Transplantation and Immune Effector Cell Therapy: Guidelines from the American Society for Transplantation and Cellular Therapy

Kanate, A. S., Majhail, N. S., Savani, B. N., Bredeson, C., Champlin, R. E., Crawford, S., Giralt, S. A., LeMaistre, C. F., Marks, D. I., Omel, J. L., Orchard, P. J., Palmer, J., Saber, W., Veys, P. A., Carpenter, P. A. & Hamadani, M., Jan 1 2020, (Accepted/In press) In : Biology of Blood and Marrow Transplantation.

Research output: Contribution to journalArticle

Open Access

Integration of Comprehensive Genomic Analysis and Functional Screening of Affected Molecular Pathways to Inform Cancer Therapy

Vasmatzis, G., Liu, M. C., Reganti, S., Feathers, R. W., Smadbeck, J., Johnson, S. H., Schaefer Klein, J. L., Harris, F. R., Yang, L., Kosari, F., Murphy, S. J., Borad, M. J., Thompson, E. A., Cheville, J. C. & Anastasiadis, P. Z., Feb 2020, In : Mayo Clinic proceedings. 95, 2, p. 306-318 13 p.

Research output: Contribution to journalArticle

Open Access

Interobserver Agreement for Classifying Post-liver Transplant Biliary Strictures in Donation After Circulatory Death Donors

Kohli, D. R., Pannala, R., Crowell, M. D., Fukami, N., Faigel, D. O., Aqel, B. A. & Harrison, M. E., Jan 1 2020, (Accepted/In press) In : Digestive Diseases and Sciences.

Research output: Contribution to journalArticle

Intravital imaging of eosinophils: Unwrapping the enigma

Nguyen, W. N. T., Jacobsen, E. A., Finney, C. A. M., Colarusso, P. & Patel, K. D., Jan 1 2020, (Accepted/In press) In : Journal of Leukocyte Biology.

Research output: Contribution to journalReview article

Kinetics of Gallbladder Emptying During Cholecystokinin Cholescintigraphy as an Indicator of In Vivo Hormonal Sensitivity

Miller, L. J., Harikumar, K. G., Desai, A. J., Siddiki, H. & Nguyen, B. D., Mar 1 2020, In : Journal of nuclear medicine technology. 48, 1, p. 40-45 6 p.

Research output: Contribution to journalArticle

Landscape of Health-Related Quality of Life in Patients With Early-Stage Pancreatic Cancer Receiving Adjuvant or Neoadjuvant Chemotherapy: A Systematic Literature Review

Macarulla, T., Hendifar, A. E., Li, C. P., Reni, M., Riess, H., Tempero, M. A., Dueck, A. C., Botteman, M. F., Deshpande, C. G., Lucas, E. J. & Oh, D. Y., Mar 1 2020, In : Pancreas. 49, 3, p. 393-407 15 p.

Research output: Contribution to journalArticle

Long-term cardiac outcomes of patients with HER2-positive breast cancer treated in the adjuvant lapatinib and/or trastuzumab Treatment Optimization Trial

Eiger, D., Pondé, N. F., Agbor-Tarh, D., Moreno-Aspitia, A., Piccart, M., Hilbers, F. S., Werner, O., Chumsri, S., Dueck, A., Kroep, J. R., Gomez, H., Láng, I., Rodeheffer, R. J., Ewer, M. S., Suter, T. & de Azambuja, E., May 12 2020, In : British journal of cancer. 122, 10, p. 1453-1460 8 p.

Research output: Contribution to journalArticle

Open Access

Molecular characterization of sarcomatoid clear cell renal cell carcinoma unveils new candidate oncogenic drivers

Malouf, G. G., Flippot, R., Dong, Y., Dinatale, R. G., Chen, Y. B., Su, X., Compérat, E., Rouprêt, M., Mano, R., Blum, K. A., Yao, H., Mouawad, R., Spano, J. P., Khayat, D., Karam, J. A., Ho, T. H., Tickoo, S. K., Russo, P., Hsieh, J. J., Tannir, N. M. & 1 others, Hakimi, A. A., Dec 1 2020, In : Scientific reports. 10, 1, 701.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Molecular inhibitor of QSOX1 suppresses tumor growth in vivo

Fifield, A. L., Hanavan, P. D., Faigel, D. O., Sergienko, E., Bobkov, A., Meurice, N., Petit, J. L., Polito, A., Caulfield, T. R., Castle, E. P., Copland, J. A., Mukhopadhyay, D., Pal, K., Dutta, S. K., Luo, H., Ho, T. H. & Lake, D. F., Jan 1 2020, In : Molecular cancer therapeutics. 19, 1, p. 112-122 11 p.

Research output: Contribution to journalArticle

Neuropsychological decline up to 20 years before incident mild cognitive impairment

Caselli, R. J., Langlais, B. T., Dueck, A. C., Chen, Y., Su, Y., Locke, D. E. C., Woodruff, B. K. & Reiman, E. M., Mar 1 2020, In : Alzheimer's and Dementia. 16, 3, p. 512-523 12 p.

Research output: Contribution to journalArticle

Noninvasive Diagnosis of Eosinophilic Esophagitis: The Nuclear Medicine Option

Wright, B. L. & Kita, H., Mar 2020, In : Mayo Clinic proceedings. 95, 3, p. 432-434 3 p.

Research output: Contribution to journalEditorial

Open Access

Novel role of Tieg1 in muscle metabolism and mitochondrial oxidative capacities

Kammoun, M., Piquereau, J., Nadal-Desbarats, L., Même, S., Beuvin, M., Bonne, G., Veksler, V., Le Fur, Y., Pouletaut, P., Même, W., Szeremeta, F., Constans, J. M., Bruinsma, E. S., Nelson Holte, M. H., Najafova, Z., Johnsen, S. A., Subramaniam, M., Hawse, J. R. & Bensamoun, S. F., Mar 1 2020, In : Acta Physiologica. 228, 3, e13394.

Research output: Contribution to journalArticle

Once-weekly (70 mg/m2) vs twice-weekly (56 mg/m2) dosing of carfilzomib in patients with relapsed or refractory multiple myeloma: A post hoc analysis of the ENDEAVOR, A.R.R.O.W., and CHAMPION-1 trials

Moreau, P., Stewart, K. A., Dimopoulos, M., Siegel, D., Facon, T., Berenson, J., Raje, N., Berdeja, J. G., Orlowski, R. Z., Yang, H., Ma, H., Klippel, Z., Zahlten-Kumeli, A., Mezzi, K., Iskander, K. & Mateos, M. V., Jan 1 2020, (Accepted/In press) In : Cancer medicine.

Research output: Contribution to journalArticle

Open Access

Overcoming resistance to anabolic SARM therapy in experimental cancer cachexia with an HDAC inhibitor

Liva, S. G., Tseng, Y. C., Dauki, A. M., Sovic, M. G., Vu, T., Henderson, S. E., Kuo, Y. C., Benedict, J. A., Zhang, X., Remaily, B. C., Kulp, S. K., Campbell, M., Bekaii-Saab, T., Phelps, M. A., Chen, C. S. & Coss, C. C., Feb 7 2020, In : EMBO Molecular Medicine. 12, 2, e9910.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Pancreatic triglyceride lipase mediates lipotoxic systemic inflammation

de Oliveira, C., Khatua, B., Noel, P., Kostenko, S., Bag, A., Balakrishnan, B., Patel, K. S., Guerra, A. A., Martinez, M. N., Trivedi, S., McCullough, A., Lam-Himlin, D. M., Navina, S., Faigel, D. O., Fukami, N., Pannala, R., Phillips, A. E., Papachristou, G. I., Kershaw, E. E., Lowe, M. E. & 1 others, Singh, V. P., Apr 1 2020, In : Journal of Clinical Investigation. 130, 4, p. 1931-1947 17 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Patient reported symptoms associated with quality of life during chemo- or immunotherapy for bladder cancer patients with advanced disease

Taarnhøj, G. A., Johansen, C., Lindberg, H., Basch, E., Dueck, A. & Pappot, H., Jan 1 2020, (Accepted/In press) In : Cancer medicine.

Research output: Contribution to journalArticle

Open Access

Patient specific characterization of artery and plaque material properties in peripheral artery disease

Noble, C., Carlson, K. D., Neumann, E., Dragomir-Daescu, D., Erdemir, A., Lerman, A. & Young, M., Jan 2020, In : Journal of the Mechanical Behavior of Biomedical Materials. 101, 103453.

Research output: Contribution to journalArticle

Open Access

Phase 1 trial of Vismodegib and Erlotinib combination in metastatic pancreatic cancer

McCleary-Wheeler, A. L., Carr, R. M., Palmer, S. R., Smyrk, T. C., Allred, J. B., Almada, L. L., Tolosa, E. J., Lamberti, M. J., Marks, D. L., Borad, M. J., Molina, J. R., Qi, Y., Lingle, W. L., Grothey, A., Pitot, H. C., Jatoi, A., Northfelt, D. W., Bryce, A. H., McWilliams, R. R., Okuno, S. H. & 10 others, Haluska, P., Kim, G. P., Colon-Otero, G., Lowe, V. J., Callstrom, M. R., Ma, W. W., Bekaii-Saab, T., Hung, M. C., Erlichman, C. & Fernandez-Zapico, M. E., Jan 2020, In : Pancreatology. 20, 1, p. 101-109 9 p.

Research output: Contribution to journalArticle

Phase Ib Trial of the PI3K Inhibitor Copanlisib Combined with the Allosteric MEK Inhibitor Refametinib in Patients with Advanced Cancer

Ramanathan, R. K., Von Hoff, D. D., Eskens, F., Blumenschein, G., Richards, D., Genvresse, I., Reschke, S., Granvil, C., Skubala, A., Peña, C. & Mross, K., Apr 1 2020, In : Targeted Oncology. 15, 2, p. 163-174 12 p.

Research output: Contribution to journalArticle

Phase I Dose-Escalation and -Expansion Study of Telisotuzumab (ABT-700), an Anti-c-Met Antibody, in Patients with Advanced Solid Tumors

Strickler, J. H., LoRusso, P., Salgia, R., Kang, Y. K., Yen, C. J., Lin, C. C., Ansell, P., Motwani, M., Wong, S., Yue, H., Wang, L., Reilly, E., Afar, D., Naumovski, L. & Ramanathan, R. K., May 1 2020, In : Molecular cancer therapeutics. 19, 5, p. 1210-1217 8 p.

Research output: Contribution to journalArticle

Open Access

Phase II Trial of Trifluridine/Tipiracil in Patients with Advanced, Refractory Biliary Tract Carcinoma

Chakrabarti, S., Zemla, T. J., Ahn, D. H., Ou, F. S., Fruth, B., Borad, M. J., Hartgers, M. L., Wessling, J., Walkes, R. L., Alberts, S. R., McWilliams, R. R., Liu, M. C., Durgin, L. M., Bekaii-Saab, T. S. & Mahipal, A., May 1 2020, In : Oncologist. 25, 5, p. 380-e763

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Prospective multicenter study to evaluate capsule endoscopy competency using a validated assessment tool

Rajan, E., Martinez, M., Gorospe, E., Al Bawardy, B., Dobashi, A., Mara, K. C., Hansel, S. L., Bruining, D. H., Murray, J. A., Leggett, C. L., Nehra, V., Iyer, P. G., Pasha, S. F., Leighton, J. A., Shiff, A. D., Gurudu, S. R., Raffals, L. E., Lavey, C., Katzka, D. A. & Chen, C. H. H., May 2020, In : Gastrointestinal endoscopy. 91, 5, p. 1140-1145 6 p.

Research output: Contribution to journalArticle

PSMA ADC monotherapy in patients with progressive metastatic castration-resistant prostate cancer following abiraterone and/or enzalutamide: Efficacy and safety in open-label single-arm phase 2 study

Petrylak, D. P., Vogelzang, N. J., Chatta, K., Fleming, M. T., Smith, D. C., Appleman, L. J., Hussain, A., Modiano, M., Singh, P., Tagawa, S. T., Gore, I., McClay, E. F., Mega, A. E., Sartor, A. O., Somer, B., Wadlow, R., Shore, N. D., Olson, W. C., Stambler, N., DiPippo, V. A. & 1 others, Israel, R. J., Jan 1 2020, In : Prostate. 80, 1, p. 99-108 10 p.

Research output: Contribution to journalArticle

Randomised phase II trial (SWOG S1310) of single agent MEK inhibitor trametinib Versus 5-fluorouracil or capecitabine in refractory advanced biliary cancer

Kim, R. D., McDonough, S., El-Khoueiry, A. B., Bekaii-Saab, T. S., Stein, S. M., Sahai, V., Keogh, G. P., Kim, E. J., Baron, A. D., Siegel, A. B., Barzi, A., Guthrie, K. A., Javle, M. & Hochster, H., May 2020, In : European Journal of Cancer. 130, p. 219-227 9 p.

Research output: Contribution to journalArticle

Randomised phase II trial of gemcitabine and nab-paclitaxel with necuparanib or placebo in untreated metastatic pancreas ductal adenocarcinoma

O'Reilly, E. M., Barone, D., Mahalingam, D., Bekaii-Saab, T., Shao, S. H., Wolf, J., Rosano, M., Krause, S., Richards, D. A., Yu, K. H., Roach, J. M., Flaherty, K. T. & Ryan, D. P., Jun 2020, In : European Journal of Cancer. 132, p. 112-121 10 p.

Research output: Contribution to journalArticle

Rapid Generation of Sustainable HER2-specific T-cell Immunity in Patients with HER2 Breast Cancer using a Degenerate HLA Class II Epitope Vaccine

Knutson, K. L., Block, M. S., Norton, N., Erskine, C. L., Hobday, T. J., Dietz, A. B., Padley, D., Gustafson, M. P., Puglisi-Knutson, D., Mangskau, T. K., Chumsri, S., Dueck, A. C., Karyampudi, L., Wilson, G. & Degnim, A. C., Mar 1 2020, In : Clinical Cancer Research. 26, 5, p. 1045-1053 9 p.

Research output: Contribution to journalArticle

Rational development of a high-affinity secretin receptor antagonist

Dong, M., Harikumar, K. G., Raval, S. R., Milburn, J. E., Clark, C., Alcala-Torano, R., Mobarec, J. C., Reynolds, C. A., Ghirlanda, G., Christopoulos, A., Wootten, D., Sexton, P. M. & Miller, L. J., Jul 2020, In : Biochemical Pharmacology. 177, 113929.

Research output: Contribution to journalArticle

Real-World Dosing Patterns and Outcomes of Patients with Metastatic Pancreatic Cancer Treated with a Liposomal Irinotecan Regimen in the United States

Barzi, A., Miksad, R., Surinach, A., Corvino, F. A., Wang, S., Torres, A. Z., Mamlouk, K., Pulgar, S., Valderrama, A., Bekaii-Saab, T. & Ahn, D., Feb 1 2020, In : Pancreas. 49, 2, p. 193-200 8 p.

Research output: Contribution to journalArticle

Risk of Gastrointestinal Bleeding Increases With Combinations of Antithrombotic Agents and Patient Age

Abraham, N. S., Noseworthy, P. A., Inselman, J., Herrin, J., Yao, X., Sangaralingham, L. R., Cornish, G., Ngufor, C. & Shah, N. D., Feb 2020, In : Clinical Gastroenterology and Hepatology. 18, 2, p. 337-346.e19

Research output: Contribution to journalArticle

1 Scopus citations

Secretin effects on gastric functions, hormones and symptoms in functional dyspepsia and health: Randomized crossover trial

Brandler, J., Miller, L. J., Wang, X. J., Burton, D., Busciglio, I., Arndt, K., Harmsen, W. S. & Camilleri, M., Jan 1 2020, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 318, 4, p. G635-G645

Research output: Contribution to journalArticle

Shared Decision-Making for Administering PCV13 in Older Adults

Shah, A. A., Wallace, M. R. & Fields, H., Feb 1 2020, In : American family physician. 101, 3, p. 134-135 2 p.

Research output: Contribution to journalArticle