Hospital Internal Medicine

Research output

Research output per year 1987 2015 2016 2017 2018 2020 2021 2022 2024

• 254 Article
• 41 Review article
• 12 Comment/debate
• 9 Editorial
• 24 More
  • 8 Chapter
  • 8 Conference contribution
  • 4 Letter
  • 4 Short survey

Research output per year

Research output per year

Search results

• 2024

  Clinical Trials for Special Populations: Children, Older Adults, and Rare Diseases

  Jacobson, R. M., Pignolo, R. J. & Lazaridis, K. N., Feb 2024, In: Mayo Clinic proceedings. 99, 2, p. 318-335 18 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Rare Diseases 100%
  • Clinical Trials 67%
  • Child 44%
  • Population 40%
  • Population Health 27%

• The HIF-1α and mTOR Pathways Amplify Heterotopic Ossification

  Wang, H., Kaplan, F. S. & Pignolo, R. J., Feb 2024, In: Biomolecules. 14, 2, 147.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Heterotopic Ossification 100%
  • Hypoxia-Inducible Factor 1 95%
  • Sirolimus 80%
  • Mutation 42%
  • Bone Morphogenetic Proteins 34%
• 2023

  Aging and Bone Metabolism

  Pignolo, R. J., Jan 2023, In: Comprehensive Physiology. 13, 1, p. 4355-4386 32 p.

  Research output: Contribution to journal › Article › peer-review

  • Bone and Bones 100%
  • Osteoporosis 89%
  • Skeleton 69%
  • Intrinsic Factor 41%
  • Secondary Hyperparathyroidism 41%

• AI-ECG and the Prediction of Accelerated Aging

  Pignolo, R. J., Apr 2023, In: Mayo Clinic proceedings. 98, 4, p. 502-503 2 p.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access

• An unbiased proteomics approach to identify the senescence-associated secretory phenotype of human bone marrow-derived mesenchymal stem cells

  Samsonraj, R. M., Law, S. F., Chandra, A. & Pignolo, R. J., Jun 2023, In: Bone Reports. 18, 101674.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Proteomics 83%
  • Mesenchymal Stem Cells 81%
  • 5'-O-(9-phenylxanthen-9-yl)-2'-deoxynebularine 47%
  • Ionizing Radiation 35%
  • Proteins 33%

• Application of Innovative Subject Recruitment System for Batch Enrollment: A Pilot Study

  Wi, C. I., King, K. S., Ryu, E., Natoli, T. L., Miller, R. P., Spiten, M. J., Borah, B. J., Takahashi, P. Y., Yao, X., Noseworthy, P. A., Pignolo, R. J. & Juhn, Y. J., Jan 1 2023, In: Journal of Primary Care and Community Health. 14

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Technology 100%
  • Electronic Health Records 31%
  • Research Subjects 30%
  • Patient Portals 23%
  • staff 20%

• Catheter Ablation of Atrial Fibrillation in Adult Congenital Heart Disease: Procedural Characteristics and Outcomes

  Hu, T. Y., Janga, C., Amin, M., Tan, N. Y., Hodge, D. O., Mehta, R. A., McLeod, C. J., Chiriac, A., Miranda, W. R., Connolly, H. M., Asirvatham, S. J., Deshmukh, A. J., Egbe, A. C. & Madhavan, M., Aug 1 2023, In: Circulation: Arrhythmia and Electrophysiology. 16, 8, p. 437-446 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Catheter Ablation 100%
  • Atrial Fibrillation 77%
  • Cardiac Arrhythmias 73%
  • Heart Diseases 70%
  • Recurrence 31%

• Garetosmab in fibrodysplasia ossificans progressiva: a randomized, double-blind, placebo-controlled phase 2 trial

  Di Rocco, M., Forleo-Neto, E., Pignolo, R. J., Keen, R., Orcel, P., Funck-Brentano, T., Roux, C., Kolta, S., Madeo, A., Bubbear, J. S., Tabarkiewicz, J., Szczepanek, M., Bachiller-Corral, J., Cheung, A. M., Dahir, K. M., Botman, E., Raijmakers, P. G., Mukaddam, M. A., Tile, L., Portal-Celhay, C., & 16 othersSarkar, N., Hou, P., Musser, B. J., Boyapati, A., Mohammadi, K., Mellis, S. J., Rankin, A. J., Economides, A. N., Trotter, D. G., Herman, G. A., O’Meara, S. J., DelGizzi, R., Weinreich, D. M., Yancopoulos, G. D., Eekhoff, E. M. W. & Kaplan, F. S., Oct 2023, In: Nature Medicine. 29, 10, p. 2615-2624 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Myositis Ossificans 100%
  • Heterotopic Ossification 89%
  • Safety 57%
  • Placebos 46%
  • Genetic Crossing Over 19%

• Global well-being, anxiety, social isolation, and emotional support among hospitalists during COVID-19 and Mpox outbreaks

  Dugani, S. B., Fischer, K. M., Schroeder, D. R., Geyer, H. L., Maniaci, M. J., Paulson, M., Croghan, I. T. & Burton, M. C., 2023, In: Hospital Practice. 51, 4, p. 211-218 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hospitalists 100%
  • Coronavirus 85%
  • Social Isolation 84%
  • Disease Outbreaks 60%
  • Error 50%

• Incidence of Respiratory Syncytial Virus Infection in Older Adults before and during the COVID-19 Pandemic

  Juhn, Y. J., Wi, C. I., Takahashi, P. Y., Ryu, E., King, K. S., Hickman, J. A., Yao, J. D., Binnicker, M. J., Natoli, T. L., Evans, T. K., Sampathkumar, P., Patten, C., Luyts, D., Pirçon, J. Y., Damaso, S. & Pignolo, R. J., Jan 20 2023, In: JAMA Network Open. 6, 1, p. E2250634

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Respiratory Syncytial Virus Infections 100%
  • Respiratory Syncytial Viruses 90%
  • Pandemics 82%
  • Respiratory Tract Infections 57%
  • Incidence 37%

• In vitro and in vivo effects of zoledronic acid on senescence and senescence-associated secretory phenotype markers

  Samakkarnthai, P., Saul, D., Zhang, L., Aversa, Z., Doolittle, M. L., Sfeir, J. G., Kaur, J., Atkinson, E. J., Edwards, J. R., Russell, G. G., Pignolo, R. J., Kirkland, J. L., Tchkonia, T., Niedernhofer, L. J., Monroe, D. G., Lebrasseur, N. K., Farr, J. N., Robbins, P. D. & Khosla, S., 2023, In: Aging. 15, 9, p. 3331-3355 25 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Zoledronic Acid 100%
  • In Vitro Techniques 33%
  • Fibroblasts 12%
  • DNA Repair-Deficiency Disorders 12%
  • Single-Cell Analysis 11%

• Local senolysis in aged mice only partially replicates the benefits of systemic senolysis

  Farr, J. N., Saul, D., Doolittle, M. L., Kaur, J., Rowsey, J. L., Vos, S. J., Froemming, M. N., Lagnado, A. B., Zhu, Y., Weivoda, M., Ikeno, Y., Pignolo, R. J., Niedernhofer, L. J., Robbins, P. D., Jurk, D., Passos, J. F., LeBrasseur, N. K., Tchkonia, T., Kirkland, J. L., Monroe, D. G., & 1 othersKhosla, S., Apr 17 2023, In: Journal of Clinical Investigation. 133, 8, e162519.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Osteocytes 100%
  • Bone and Bones 94%
  • Osteoclasts 82%
  • Adipocytes 75%
  • Femur 73%

• Most Fractures Treated Nonoperatively in Individuals with Fibrodysplasia Ossificans Progressiva Heal with a Paucity of Flareups, Heterotopic Ossification, and Loss of Mobility

  Lindborg, C. M., Al Mukaddam, M., Baujat, G., Cho, T. J., De Cunto, C. L., Delai, P. L. R., Eekhoff, E. M. W., Haga, N., Hsiao, E. C., Morhart, R., De Ruiter, R., Scott, C., Seemann, P., Szczepanek, M., Tabarkiewicz, J., Pignolo, R. J. & Kaplan, F. S., Dec 1 2023, In: Clinical orthopaedics and related research. 481, 12, p. 2447-2458 12 p.

  Research output: Contribution to journal › Article › peer-review

• Multisite analysis of patient experience scores and risk of hospital admission: a retrospective cohort study

  Hydoub, Y. M., Fischer, K. M., Hanson, K. T., Coons, T. J., Wilshusen, L. L., Vista, T. L., Colbenson, G. A., Burton, M. C., Habermann, E. B. & Dugani, S. B., 2023, In: Hospital Practice. 51, 1, p. 35-43 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Sampling 100%
  • Cohort Studies 82%
  • Retrospective Studies 81%
  • Environment 68%
  • Patient Discharge 9%

• Reduction of New Heterotopic Ossification (HO) in the Open-Label, Phase 3 MOVE Trial of Palovarotene for Fibrodysplasia Ossificans Progressiva (FOP)

  Pignolo, R. J., Hsiao, E. C., Al Mukaddam, M., Baujat, G., Berglund, S. K., Brown, M. A., Cheung, A. M., De Cunto, C., Delai, P., Haga, N., Kannu, P., Keen, R., Le Quan Sang, K. H., Mancilla, E. E., Marino, R., Strahs, A. & Kaplan, F. S., Mar 2023, In: Journal of Bone and Mineral Research. 38, 3, p. 381-394 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Palovarotene 100%
  • Myositis Ossificans 70%
  • Heterotopic Ossification 62%
  • Tomography 16%
  • Bone Density 14%

• Study methodology and insights from the palovarotene clinical development program in fibrodysplasia ossificans progressiva

  Pignolo, R. J., Al Mukaddam, M., Baujat, G., Brown, M. A., De Cunto, C., Hsiao, E. C., Keen, R., Le Quan Sang, K. H., Grogan, D. R., Marino, R., Strahs, A. R. & Kaplan, F. S., Dec 2023, In: BMC Medical Research Methodology. 23, 1, 269.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Palovarotene 100%
  • Myositis Ossificans 70%
  • Natural History 38%
  • Heterotopic Ossification 37%
  • Patient Reported Outcome Measures 20%

• Successful Aging: The Longer One Lives, the Better One Has Eaten?

  Pignolo, R. J., Dec 2023, In: Mayo Clinic proceedings. 98, 12, p. 1751-1752 2 p.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access

• The effects of palovarotene in patients with fibrodysplasia ossificans progressiva: A plain language summary

  Pignolo, R. J., Hsiao, E. C., Mukaddam, M. A., Baujat, G., Berglund, S. K., Brown, M. A., Cheung, A. M., De Cunto, C., Delai, P., Haga, N., Kannu, P., Keen, R., Quan Sang, K. H. L., Mancilla, E. E., Marino, R., Strahs, A. & Kaplan, F. S., Jan 1 2023, In: Future Rare Diseases. 3, 1, FRD33.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Palovarotene 100%
  • Myositis Ossificans 70%
  • Language 37%
  • Skeleton 12%
  • Bone and Bones 10%

• The Fibrodysplasia Ossificans Progressiva Physical Function Questionnaire (FOP-PFQ): A patient-reported, disease-specific measure

  Pignolo, R. J., Kimel, M., Whalen, J., Kawata, A. K., Artyomenko, A. & Kaplan, F. S., Mar 2023, In: Bone. 168, 116642.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Myositis Ossificans 100%
  • Heterotopic Ossification 44%
  • Joints 23%
  • Reproducibility of Results 20%
  • Statistical Factor Analysis 20%
• 2022

  Accelerated Aging in Cyclophilin B–Deficient Mice Downstream of p21-Cip1/Waf1

  Zhang, Y., Pignolo, R. J. & Bram, R. J., Oct 2022, In: JBMR Plus. 6, 10, e10674.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cyclophilins 100%
  • Osteogenesis Imperfecta 90%
  • cyclophilin B 86%
  • beta-Galactosidase 32%
  • Kyphosis 23%

• An ACVR1^R375P pathogenic variant in two families with mild fibrodysplasia ossificans progressiva

  Kaplan, F. S., Groppe, J. C., Xu, M., Towler, O. W., Grunvald, E., Kalunian, K., Kallish, S., Al Mukaddam, M., Pignolo, R. J. & Shore, E. M., Mar 2022, In: American Journal of Medical Genetics, Part A. 188, 3, p. 806-817 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Myositis Ossificans 100%
  • Phenotype 27%
  • Genetic Counseling 24%
  • Proline 23%
  • Codon 22%

• A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues

  Saul, D., Kosinsky, R. L., Atkinson, E. J., Doolittle, M. L., Zhang, X., LeBrasseur, N. K., Pignolo, R. J., Robbins, P. D., Niedernhofer, L. J., Ikeno, Y., Jurk, D., Passos, J. F., Hickson, L. T. J., Xue, A., Monroe, D. G., Tchkonia, T., Kirkland, J. L., Farr, J. N. & Khosla, S., Dec 2022, In: Nature communications. 13, 1, 4827.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • genes 100%
  • Clearance 92%
  • cells 45%
  • Genes 34%
  • bones 27%

• Assessing Naltrexone Prescribing and Barriers to Initiation for Alcohol Use Disorder: A Multidisciplinary, Multisite Survey

  Leung, J. G., Narayanan, P. P., Markota, M., Miller, N. E., Philbrick, K. L., Burton, M. C. & Kirchoff, R. W., May 10 2022, In: Frontiers in Psychiatry. 13, 856938.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Naltrexone 100%
  • Alcoholism 72%
  • Internal Medicine 41%
  • Psychiatry 29%
  • Medicine 14%

• Association between emergency department modifiable risk factors and subsequent delirium among hospitalized older adults

  Oliveira J. e Silva, L., Stanich, J. A., Jeffery, M. M., Lindroth, H. L., Miller, D. M., Campbell, R. L., Rabinstein, A. A., Pignolo, R. J. & Bellolio, F., Mar 2022, In: American Journal of Emergency Medicine. 53, p. 201-207 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Delirium 100%
  • Hospital Emergency Service 69%
  • Confidence Intervals 22%
  • Odds Ratio 21%
  • Opioid Analgesics 19%

• Atrial Arrhythmia Ablation in Patients with D-Transposition of the Great Arteries and Atrial Switch

  Chiriac, A., Cheema, K. P., Giardi, D., Espinosa, S. M., Fitzgerald, P., Perez-Downes, J. C., Umadat, G., Hodge, D. O., Phillips, S. D., Madhavan, M., Asirvatham, S. J. & McLeod, C. J., Jul 1 2022, In: Circulation: Arrhythmia and Electrophysiology. 15, 7, p. E010546

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Transposition of Great Vessels 100%
  • Cardiac Arrhythmias 65%
  • Tachycardia 47%
  • Atrioventricular Nodal Reentry Tachycardia 20%
  • Recurrence 16%

• Bone Marrow Adiposity in Models of Radiation- and Aging-Related Bone Loss Is Dependent on Cellular Senescence

  Chandra, A., Lagnado, A. B., Farr, J. N., Schleusner, M., Monroe, D. G., Saul, D., Passos, J. F., Khosla, S. & Pignolo, R. J., May 2022, In: Journal of Bone and Mineral Research. 37, 5, p. 997-1011 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Adiposity 95%
  • Adipocytes 86%
  • Radiation 68%
  • Bone Marrow 66%
  • Bone and Bones 54%

• Bridging the geroscience chasm between bench and bedside

  Tung, E. E., Weavers, K. M., Kirkland, J. L. & Pignolo, R. J., 2022, In: Gerontology and Geriatrics Education. 43, 2, p. 250-256 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Translational Medical Research 100%
  • Education 55%
  • Curriculum 43%
  • Geriatrics 42%
  • Medicine 32%

• Clearance of Senescent Cells From Injured Muscle Abrogates Heterotopic Ossification in Mouse Models of Fibrodysplasia Ossificans Progressiva

  Wang, H., Zhang, Q., Kaplan, F. S. & Pignolo, R. J., Jan 2022, In: Journal of Bone and Mineral Research. 37, 1, p. 95-107 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Myositis Ossificans 100%
  • Heterotopic Ossification 89%
  • Muscles 40%
  • Type I Bone Morphogenetic Protein Receptors 13%
  • Activin Receptors 12%

• Current challenges and opportunities in the care of patients with fibrodysplasia ossificans progressiva (FOP): an international, multi-stakeholder perspective

  Pignolo, R. J., Bedford-Gay, C., Cali, A., Davis, M., Delai, P. L. R., Gonzales, K., Hixson, C., Kent, A., Newport, H., Robert, M., Scott, C. & Kaplan, F. S., Dec 2022, In: Orphanet Journal of Rare Diseases. 17, 1, 168.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Myositis Ossificans 100%
  • Patient Care 52%
  • Organizations 9%
  • Medical Writing 6%
  • Tin 5%

• Functional Testing of Bone Morphogenetic Protein (BMP) Pathway Variants Identified on Whole-Exome Sequencing in a Patient with Delayed-Onset Fibrodysplasia Ossificans Progressiva (FOP) Using ACVR1^R206H-Specific Human Cellular and Zebrafish Models

  Wentworth, K. L., Lalonde, R. L., Groppe, J. C., Brewer, N., Moody, T., Hansberry, S., Taylor, K. E., Shore, E. M., Kaplan, F. S., Pignolo, R. J., Yelick, P. C. & Hsiao, E. C., Nov 2022, In: Journal of Bone and Mineral Research. 37, 11, p. 2058-2076 19 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Myositis Ossificans 100%
  • Bone Morphogenetic Proteins 82%
  • Whole Exome Sequencing 80%
  • Zebrafish 68%
  • activin A 46%

• Gene Therapy for Fibrodysplasia Ossificans Progressiva: Feasibility and Obstacles

  Eekhoff, E. M. W., De Ruiter, R. D., Smilde, B. J., Schoenmaker, T., De Vries, T. J., Netelenbos, C., Hsiao, E. C., Scott, C., Haga, N., Grunwald, Z., De Cunto, C. L., Di Rocco, M., Delai, P. L. R., Diecidue, R. J., Madhuri, V., Cho, T. J., Morhart, R., Friedman, C. S., Zasloff, M., Pals, G., & 5 othersShim, J. H., Gao, G., Kaplan, F., Pignolo, R. J. & Micha, D., Aug 1 2022, In: Human gene therapy. 33, 15-16, p. 782-788 7 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Myositis Ossificans 100%
  • Genetic Therapy 62%
  • Bone and Bones 20%
  • Skeleton 17%
  • Connective Tissue 15%

• Influenza infection is not associated with phenotypical frailty in older patients, a prospective cohort study

  Takahashi, P., Wi, C. I., Ryu, E., King, K., Hickman, J., Pignolo, R. & Juhn, Y., Sep 2022, In: Health Science Reports. 5, 5, e750.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Frailty 100%
  • Human Influenza 80%
  • Cohort Studies 59%
  • Prospective Studies 55%
  • Infections 41%

• Palovarotene for Fibrodysplasia Ossificans Progressiva (FOP): Results of a Randomized, Placebo-Controlled, Double-Blind Phase 2 Trial

  Pignolo, R. J., Baujat, G., Hsiao, E. C., Keen, R., Wilson, A., Packman, J., Strahs, A. L., Grogan, D. R. & Kaplan, F. S., Oct 2022, In: Journal of Bone and Mineral Research. 37, 10, p. 1891-1902 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Palovarotene 100%
  • Myositis Ossificans 70%
  • Placebos 32%
  • Heterotopic Ossification 31%
  • retinoic acid receptor gamma 5%

• Plasma-Soluble Biomarkers for Fibrodysplasia Ossificans Progressiva (FOP) Reflect Acute and Chronic Inflammatory States

  Pignolo, R. J., McCarrick-Walmsley, R., Wang, H., Qiu, S., Hunter, J., Barr, S., He, K., Zhang, H. & Kaplan, F. S., Mar 2022, In: Journal of Bone and Mineral Research. 37, 3, p. 475-483 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Myositis Ossificans 100%
  • Biomarkers 43%
  • Kallikreins 24%
  • Genotype 13%
  • Tenascin 12%

• Post-discharge early assessment with remote video link (PEARL) initiative for patients discharged from hospital medicine services

  Dugani, S. B., Kiliaki, S. A., Nielsen, M. L., Coons, T. J., Fischer, K. M., Parikh, R. S., Pagali, S. R., Liwonjo, A., Schroeder, D. R., Croghan, I. T. & Burton, M. C., 2022, In: Hospital Practice. 50, 5, p. 379-386 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Narcotic 100%
  • Hospital Medicine 94%
  • Ambulatory Care 39%
  • Patient Compliance 19%
  • Telephone 19%

• Primary cilia in satellite cells are the mechanical sensors for muscle hypertrophy

  Li, W., Zhu, Z., He, K., Ma, X., Pignolo, R. J., Sieck, G. C., Hu, J. & Wang, H., Jun 14 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 24, e2103615119.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cilia 100%
  • Hypertrophy 78%
  • Factor V 73%
  • Muscles 51%
  • Hedgehogs 37%

• Psychologic wellness of PA, NP, and physician hospitalists during the COVID-19 pandemic

  Dugani, S. B., Fischer, K. M., Geyer, H. L., Maniaci, M. J., Croghan, I. T. & Burton, M. C., May 1 2022, In: Journal of the American Academy of Physician Assistants. 35, 5, p. 45-53 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hospitalists 100%
  • Pandemics 72%
  • Physicians 42%
  • Logistic Models 35%
  • Social Isolation 33%

• REcognizing DElirium in geriatric Emergency Medicine: The REDEEM risk stratification score

  Oliveira J. e Silva, L., Stanich, J. A., Jeffery, M. M., Mullan, A. F., Bower, S. M., Campbell, R. L., Rabinstein, A. A., Pignolo, R. J. & Bellolio, F., Apr 2022, In: Academic Emergency Medicine. 29, 4, p. 476-485 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Emergency Medicine 100%
  • Delirium 97%
  • Geriatrics 81%
  • Hospital Emergency Service 54%
  • Confidence Intervals 25%

• Targeted clearance of p21- but not p16-positive senescent cells prevents radiation-induced osteoporosis and increased marrow adiposity

  Chandra, A., Lagnado, A. B., Farr, J. N., Doolittle, M., Tchkonia, T., Kirkland, J. L., LeBrasseur, N. K., Robbins, P. D., Niedernhofer, L. J., Ikeno, Y., Passos, J. F., Monroe, D. G., Pignolo, R. J. & Khosla, S., May 2022, In: Aging Cell. 21, 5, e13602.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Adiposity 100%
  • Osteoporosis 84%
  • Radiation 71%
  • Bone Marrow 70%
  • Transgenic Suicide Genes 32%

• The natural history of fibrodysplasia ossificans progressiva: A prospective, global 36-month study

  Pignolo, R. J., Baujat, G., Brown, M. A., De Cunto, C., Hsiao, E. C., Keen, R., Al Mukaddam, M., Le Quan Sang, K. H., Wilson, A., Marino, R., Strahs, A. & Kaplan, F. S., Dec 2022, In: Genetics in Medicine. 24, 12, p. 2422-2433 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Myositis Ossificans 100%
  • Heterotopic Ossification 89%
  • Natural History 27%
  • Back 13%
  • Inborn Genetic Diseases 12%

• Validation and Recalibration of Modified Mayo Delirium Prediction Tool in a Hospitalized Cohort

  Pagali, S. R., Fischer, K. M., Kashiwagi, D. T., Schroeder, D. R., Philbrick, K. L., Lapid, M. I., Pignolo, R. J. & Burton, M. C., Nov 1 2022, In: Journal of the Academy of Consultation-Liaison Psychiatry. 63, 6, p. 521-528 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Delirium 100%
  • recipient 15%
  • Accidental Falls 10%
  • Datasets 10%
  • hospital admission 8%

• Wellness of hospitalists and hospital medicine advanced practice providers during the COVID-19 pandemic, 2020–2021

  Dugani, S. B., Fischer, K. M., Schroeder, D. R., Geyer, H. L., Maniaci, M. J., Croghan, I. T., Kashani, D. & Burton, M. C., Apr 2022, In: Journal of hospital medicine. 17, 4, p. 259-267 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hospitalists 100%
  • Hospital Medicine 91%
  • Coronavirus 85%
  • Pandemics 72%
  • medicine 49%

• “I Can’t Take off My Shirt or Do My Own Hair”—A Qualitative Investigation of the Symptoms and Impact Experience of Children and Adolescents with Fibrodysplasia Ossificans Progressiva (FOP)

  Markowitz, J. T., Rofail, D., Vandenberg, G., Baldasaro, J., Sanchez, R. J., Pignolo, R. J., Keen, R., Davis, M. & Marquis, P., Jun 2022, In: Advances in Therapy. 39, 6, p. 2796-2805 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Myositis Ossificans 100%
  • Child 29%
  • Parents 25%
  • Qualitative Research 13%
  • Activities of Daily Living 11%
• 2021

  Adherence to Public Health Measures Mitigates the Risk of COVID-19 Infection in Older Adults: A Community-Based Study

  Juhn, Y. J., Wi, C. I., Ryu, E., Sampathkumar, P., Takahashi, P. Y., Yao, J. D., Binnicker, M. J., Natoli, T. L., Evans, T. K., King, K. S., Volpe, S., Pirçon, J. Y., Silvia Damaso, D. & Pignolo, R. J., Apr 2021, In: Mayo Clinic proceedings. 96, 4, p. 912-920 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Coronavirus 100%
  • Public Health 56%
  • Infections 37%
  • Severe Acute Respiratory Syndrome 29%
  • Coronaviridae 20%

• Antidiabetic Effects of the Senolytic Agent Dasatinib

  Salaami, O., Kuo, C. L., Drake, M. T., Kuchel, G. A., Kirkland, J. L. & Pignolo, R. J., Dec 2021, In: Mayo Clinic proceedings. 96, 12, p. 3021-3029 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Dasatinib 100%
  • Hypoglycemic Agents 68%
  • Imatinib Mesylate 41%
  • Glucose 22%
  • Protein-Tyrosine Kinases 21%

• A Taxonomic Review of Patient Complaints in Adult Hospital Medicine

  Elias, R. M., Fischer, K. M., Siddiqui, M. A., Coons, T., Meyerhofer, C. A., Pretzman, H. J., Greig, H. E., Stevens, S. K. & Burton, M. C., 2021, In: Journal of Patient Experience. 8

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hospital Medicine 100%
  • complaint 71%
  • medicine 53%
  • Internal Medicine 51%
  • Quality of Health Care 21%

• Bone Aging, Cellular Senescence, and Osteoporosis

  Pignolo, R. J., Law, S. F. & Chandra, A., Apr 2021, In: JBMR Plus. 5, 4, e10488.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Osteoporosis 80%
  • Bone and Bones 54%
  • Genetic Predisposition to Disease 9%
  • Hemostasis 9%
  • Radiation 6%

• Bone From Blood: Characteristics and Clinical Implications of Circulating Osteogenic Progenitor (COP) Cells

  Feehan, J., Kassem, M., Pignolo, R. J. & Duque, G., Jan 2021, In: Journal of Bone and Mineral Research. 36, 1, p. 12-23 12 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Stem Cells 100%
  • Musculoskeletal Diseases 91%
  • Musculoskeletal System 84%
  • Bone and Bones 80%
  • Mesoderm 73%
  2 Scopus citations

• Choosing the Device Generator and Leads: Matching the Device with the Patient

  McLeod, C. J., Chiriac, A., Madhavan, M., Hayes, D. L., Friedman, P. A. & Asirvatham, S. J., Jan 1 2021, Cardiac Pacing, Defibrillation and Resynchronization: A Clinical Approach, Fourth Edition. wiley, p. 125-148 24 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Cardiac Resynchronization Therapy 100%
  • Equipment and Supplies 97%
  • Vasovagal Syncope 58%
  • Carotid Sinus 54%
  • Defibrillators 49%

• Correction to: Spiritual Care of Inpatients Focusing on Outcomes and the Role of Chaplaincy Services: A Systematic Review (Journal of Religion and Health, (2021), 60, 2, (1406-1422), 10.1007/s10943-021-01191-z)

  Kirchoff, R. W., Tata, B., McHugh, J., Kingsley, T., Burton, M. C., Manning, D., Lapid, M. & Chaudhary, R., Jun 2021, In: Journal of Religion and Health. 60, 3, p. 2190 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Systematic Review 100%
  • Chaplaincy 100%
  • Spiritual Care 90%
  • Religion 83%
  • Inpatients 57%