Hospital Internal Medicine

Research Output

2020

Are pre-existing psychiatric disorders the only reason for involuntary holds in the emergency department?

Lachner, C., Maniaci, M. J., Vadeboncoeur, T. F., Dawson, N. L., Rummans, T. A., Roy, A., Hall, L. L. & Burton, M. C., Feb 3 2020, In : International Journal of Emergency Medicine. 13, 1, 4.

Research output: Contribution to journalArticle

Open Access

Common substance use disorders in older adults

Seim, L., Vijapura, P., Pagali, S. & Burton, M. C., Mar 1 2020, In : Hospital practice (1995). 48, p. 48-55 8 p.

Research output: Contribution to journalArticle

Open Access

Corrigendum to ‘Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease’ (EBioMedicine (2019) 47 (446–456), (S2352396419305912), (10.1016/j.ebiom.2019.08.069))

Hickson, L. T. J., Langhi Prata, L. G. P., Bobart, S. A., Evans, T. K., Giorgadze, N., Hashmi, S. K., Herrmann, S. M., Jensen, M. D., Jia, Q., Jordan, K. L., Kellogg, T. A., Khosla, S., Koerber, D. M., Lagnado, A. B., Lawson, D. K., LeBrasseur, N. K., Lerman, L. O., McDonald, K. M., McKenzie, T. J., Passos, J. F. & 18 others, Pignolo, R. J., Pirtskhalava, T., Saadiq, I. M., Schaefer, K. K., Textor, S. C., Victorelli, S. G., Volkman, T. L., Xue, A., Wentworth, M. A., Wissler Gerdes, E. O., Allison, D. B., Dickinson, S. L., Ejima, K., Atkinson, E. J., Lenburg, M., Zhu, Y., Tchkonia, T. & Kirkland, J. L., Feb 2020, In : EBioMedicine. 52, 102595.

Research output: Contribution to journalComment/debate

Open Access
3 Scopus citations

Druggable targets, clinical trial design and proposed pharmacological management in fibrodysplasia ossificans progressiva

Pignolo, R. J. & Kaplan, F. S., Apr 2 2020, In : Expert Opinion on Orphan Drugs. 8, 4, p. 101-109 9 p.

Research output: Contribution to journalReview article

Fibrodysplasia Ossificans Progressiva (FOP): A Segmental Progeroid Syndrome

Pignolo, R. J., Wang, H. & Kaplan, F. S., Jan 10 2020, In : Frontiers in Endocrinology. 10, 908.

Research output: Contribution to journalReview article

Open Access
2 Scopus citations

Inpatient Care of Patients with COVID-19: A Guide for Hospitalists

Yetmar, Z. A., Issa, M., Munawar, S., Burton, M. C., Pureza, V., Sohail, M. R. & Mehmood, T., Jan 1 2020, (Accepted/In press) In : American Journal of Medicine.

Research output: Contribution to journalReview article

Open Access

Introduction to Thematic Reviews on Aging and Geriatric Medicine

Pignolo, R. J. & Nath, K. A., Jun 2020, In : Mayo Clinic proceedings. 95, 6, p. 1102-1104 3 p.

Research output: Contribution to journalEditorial

Open Access

Involuntary patient length-of-stay at a suburban emergency department

Maniaci, M. J., Lachner, C., Vadeboncoeur, T. F., Hodge, D. O., Dawson, N. L., Rummans, T. A., Roy, A. & Burton, M. C., Mar 2020, In : American Journal of Emergency Medicine. 38, 3, p. 534-538 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Polypharmacy in older adults: the role of the multidisciplinary team

Baruth, J. M., Gentry, M. T., Rummans, T. A., Miller, D. M. & Burton, M. C., Mar 1 2020, In : Hospital practice (1995). 48, p. 56-62 7 p.

Research output: Contribution to journalReview article

Open Access

Reducing Senescent Cell Burden in Aging and Disease

Pignolo, R. J., Passos, J. F., Khosla, S., Tchkonia, T. & Kirkland, J. L., Jan 1 2020, (Accepted/In press) In : Trends in Molecular Medicine.

Research output: Contribution to journalReview article

Self-reported baseline phenotypes from the International Fibrodysplasia Ossificans Progressiva (FOP) Association Global Registry

Pignolo, R. J., Cheung, K., Kile, S., Fitzpatrick, M. A., De Cunto, C., Al Mukaddam, M., Hsiao, E. C., Baujat, G., Delai, P., Eekhoff, E. M. W., Di Rocco, M., Grunwald, Z., Haga, N., Keen, R., Levi, B., Morhart, R., Scott, C., Sherman, A., Zhang, K. & Kaplan, F. S., May 2020, In : Bone. 134, 115274.

Research output: Contribution to journalArticle

Targeted Reduction of Senescent Cell Burden Alleviates Focal Radiotherapy-Related Bone Loss

Chandra, A., Lagnado, A. B., Farr, J. N., Monroe, D. G., Park, S., Hachfeld, C., Tchkonia, T., Kirkland, J. L., Khosla, S., Passos, J. F. & Pignolo, R. J., Jun 1 2020, In : Journal of Bone and Mineral Research. 35, 6, p. 1119-1131 13 p.

Research output: Contribution to journalArticle

1 Scopus citations

Things We Do For No Reason™: Treatment of Infection-Related Fever in Hospitalized Patients

Vijapura, P., Cowart, J. B., Kashiwagi, D. T., Killebrew, S. R. & Burton, M. C., May 1 2020, In : Journal of hospital medicine. 15, 5, p. 269-271 3 p.

Research output: Contribution to journalArticle

Open Access
2019

Assessing and Counseling the Older Driver: A Concise Review for the Generalist Clinician

Hill, L. J. N., Pignolo, R. J. & Tung, E. E., Aug 2019, In : Mayo Clinic proceedings. 94, 8, p. 1582-1588 7 p.

Research output: Contribution to journalReview article

Open Access
3 Scopus citations

Canine-Assisted Therapy in Hospitalized Patients Awaiting Heart Transplantation

Snipelisky, D., Smidt, J., Gallup, S., Myrick, J., Bauer, B. A. & Burton, M. C., Jun 1 2019, In : Southern medical journal. 112, 6, p. 344-348 5 p.

Research output: Contribution to journalArticle

Case-Based PowerPoint to Improve Knowledge and Comfort of Having Code Status Discussions by Physician Assistant and Nurse Practitioner Students

Schoonover, K., Herber, A., Heusinkvelt, S., Yadav, H. & Burton, M. C., Oct 1 2019, In : Journal of palliative care. 34, 4, p. 215-217 3 p.

Research output: Contribution to journalArticle

Correction to: Natural history of fibrodysplasia ossificans progressiva: Cross-sectional analysis of annotated baseline phenotypes (Orphanet J Rare Dis (2019) 14 (98) DOI: 10.1186/s13023-019-1068-7)

Pignolo, R. J., Baujat, G., Brown, M. A., De Cunto, C., Di Rocco, M., Hsiao, E. C., Keen, R., Al Mukaddam, M., Sang, K. H. L. Q., Wilson, A., White, B., Grogan, D. R. & Kaplan, F. S., May 23 2019, In : Orphanet Journal of Rare Diseases. 14, 1, 113.

Research output: Contribution to journalComment/debate

Open Access
2 Scopus citations

Creating the Next Generation of Translational Geroscientists

Newman, J. C., Sokoloski, J. L., Robbins, P. D., Niedernhofer, L. J., Reed, M. J., Wei, J., Austad, S. N., Barzilai, N., Cohen, H. J., Kuchel, G. A., Kirkland, J. L. & Pignolo, R. J., Sep 1 2019, In : Journal of the American Geriatrics Society. 67, 9, p. 1934-1939 6 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Exceptional Human Longevity

Pignolo, R., Jan 1 2019, In : Mayo Clinic Proceedings. 94, 1, p. 110-124 15 p.

Research output: Contribution to journalReview article

12 Scopus citations

Feasibility of medical image-based bio 3D printing of variable tissue compositions

Shinde, R., Nigh, D. J. P., Miguez, S. M., Rhodes, S. S., Udupa, J. K., Shetye, S., Chandra, A., Pignolo, R. & Rajapakse, C. S., Jan 1 2019, Medical Imaging 2019: Imaging Informatics for Healthcare, Research, and Applications. Bak, P. R. & Chen, P-H. (eds.). SPIE, 1095409. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10954).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Goal-Directed Achievement Through Geographic Location (GAGL) Reduces Patient Length of Stay and Adverse Events

Maniaci, M. J., Dawson, N. L., Cowart, J. B., Richie, E. M., Suryaprasad, A. G., Hodge, D. O., Joyce, N. E., Kernan, C. A., Stone, L. A. & Burton, M. C., Jan 1 2019, (Accepted/In press) In : American Journal of Medical Quality.

Research output: Contribution to journalArticle

Molecular characterization of known and novel ACVR1 variants in phenotypes of aberrant ossification

Gupta, A., Zimmermann, M. T., Wang, H., Broski, S. M., Sigafoos, A. N., Macklin, S. K., Urrutia, R. A., Clark, K. J., Atwal, P. S., Pignolo, R. J. & Klee, E. W., Jan 1 2019, In : American Journal of Medical Genetics, Part A.

Research output: Contribution to journalArticle

3 Scopus citations

Natural history of fibrodysplasia ossificans progressiva: Cross-sectional analysis of annotated baseline phenotypes

Pignolo, R. J., Baujat, G., Brown, M. A., De Cunto, C., Dirocco, M., Hsiao, E. C., Keen, R., Al Mukaddam, M., Sang, K. H. L. Q., Wilson, A., White, B., Grogan, D. R. & Kaplan, F. S., May 3 2019, In : Orphanet Journal of Rare Diseases. 14, 1, 98.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Patients on Involuntary Hold Status in the Emergency Department

Roy, A., Lachner, C., Dumitrascu, A., Dawson, N. L., Vadeboncoeur, T. F., Maniaci, M. J., Lamoureux, I. C., Lewis, P. C., Rummans, T. A. & Burton, M. C., May 1 2019, In : Southern Medical Journal. 112, 5, p. 265-270 6 p.

Research output: Contribution to journalArticle

Open Access

Patients Threatening Harm to Others Evaluated in the Emergency Department under the Florida Involuntary Hold Act (Baker Act)

Maniaci, M. J., Burton, M. C., Lachner, C., Vadeboncoeur, T. F., Dawson, N. L., Roy, A., Dumitrascu, A. G., Lewis, P. C. & Rummans, T. A., Sep 1 2019, In : Southern medical journal. 112, 9, p. 463-468 6 p.

Research output: Contribution to journalArticle

Potential role of senescence in radiation-induced damage of the aged skeleton

Chandra, A., Park, S. S. & Pignolo, R., Mar 1 2019, In : Bone. 120, p. 423-431 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease

Hickson, L. T. J., Langhi Prata, L. G. P., Bobart, S. A., Evans, T. K., Giorgadze, N., Hashmi, S. K., Herrmann, S. M., Jensen, M. D., Jia, Q., Jordan, K. L., Kellogg, T. A., Khosla, S., Koerber, D. M., Lagnado, A. B., Lawson, D. K., LeBrasseur, N. K., Lerman, L. O., McDonald, K. M., McKenzie, T. J., Passos, J. F. & 13 others, Pignolo, R. J., Pirtskhalava, T., Saadiq, I. M., Schaefer, K. K., Textor, S. C., Victorelli, S. G., Volkman, T. L., Xue, A., Wentworth, M. A., Wissler Gerdes, E. O., Zhu, Y., Tchkonia, T. & Kirkland, J. L., Sep 2019, In : EBioMedicine. 47, p. 446-456 11 p.

Research output: Contribution to journalArticle

Open Access
44 Scopus citations

Special considerations for clinical trials in fibrodysplasia ossificans progressiva (FOP)

Hsiao, E. C., Di Rocco, M., Cali, A., Zasloff, M., Al Mukaddam, M., Pignolo, R. J., Grunwald, Z., Netelenbos, C., Keen, R., Baujat, G., Brown, M. A., Cho, T. J., De Cunto, C., Delai, P., Haga, N., Morhart, R., Scott, C., Zhang, K., Diecidue, R. J., Friedman, C. S. & 2 others, Kaplan, F. S. & Eekhoff, E. M. W., Jun 2019, In : British Journal of Clinical Pharmacology. 85, 6, p. 1199-1207 9 p.

Research output: Contribution to journalReview article

4 Scopus citations
6 Scopus citations

Targeting Cell Senescence for the Treatment of Age-Related Bone Loss

Pignolo, R. J., Samsonraj, R. M., Law, S. F., Wang, H. & Chandra, A., Apr 15 2019, In : Current osteoporosis reports. 17, 2, p. 70-85 16 p.

Research output: Contribution to journalReview article

6 Scopus citations
2018

A case report of mesenteric heterotopic ossification: Histopathologic and genetic findings

Amalfitano, M., Fyfe, B., Thomas, S. V., Egan, K. P., Xu, M., Smith, A. G., Kaplan, F. S., Shore, E. M. & Pignolo, R., Apr 1 2018, In : Bone. 109, p. 56-60 5 p.

Research output: Contribution to journalArticle

1 Scopus citations
13 Scopus citations

Acute and chronic rapamycin use in patients with Fibrodysplasia Ossificans Progressiva: A report of two cases

Kaplan, F. S., Zeitlin, L., Dunn, S. P., Benor, S., Hagin, D., Al Mukaddam, M. & Pignolo, R., Apr 1 2018, In : Bone. 109, p. 281-284 4 p.

Research output: Contribution to journalArticle

9 Scopus citations

Acute unilateral hip pain in fibrodysplasia ossificans progressiva (FOP)

Kaplan, F. S., Al Mukaddam, M. & Pignolo, R., Apr 1 2018, In : Bone. 109, p. 115-119 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Amyloidosis: A unifying diagnosis for nephrotic syndrome and congestive cardiac failure

Sara, J. D. S., Khodadadi, R., Barth, D. & Burton, M. C., Jan 1 2018, In : BMJ Case Reports. 2018, A3118.

Research output: Contribution to journalArticle

Association of anemia with outcomes of acute heart failure

Halawa, A., Burton, M. C., Maniaci, M. J., Shapiro, B. P., Yip, D. S., Hodge, D. O., Vargas, E. R. & Dawson, N., Feb 1 2018, In : Southern Medical Journal. 111, 2, p. 103-108 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Best Practices for Physician-Scientist Training Programs: Recommendations from the Alliance for Academic Internal Medicine

Blanchard, M., Burton, M. C., Geraci, M. W., Madaio, M. P., Marsh, J. D., Proweller, A., Rockey, D. C., Salata, R. A., Tan, W., Williams, C. S., Zaidi, M. & Todd, R. F., May 1 2018, In : American Journal of Medicine. 131, 5, p. 578-584 7 p.

Research output: Contribution to journalComment/debate

5 Scopus citations

Cartilage-derived retinoic acid-sensitive protein (CD-RAP): A stage-specific biomarker of heterotopic endochondral ossification (HEO) in fibrodysplasia ossificans progressiva (FOP)

Lindborg, C. M., Brennan, T. A., Wang, H., Kaplan, F. S. & Pignolo, R., Apr 1 2018, In : Bone. 109, p. 153-157 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Circulating osteogentic precursor cells in non-hereditary heterotopic ossification

Egan, K. P., Duque, G., Keenan, M. A. & Pignolo, R., Apr 1 2018, In : Bone. 109, p. 61-64 4 p.

Research output: Contribution to journalArticle

7 Scopus citations

Clinical-pathological correlations in three patients with fibrodysplasia ossificans progressiva

Wentworth, K. L., Bigay, K., Chan, T. V., Ho, J. P., Morales, B. M., Connor, J., Brooks, E., Shahriar Salamat, M., Sanchez, H. C., Wool, G., Pignolo, R., Kaplan, F. S. & Hsiao, E. C., Apr 1 2018, In : Bone. 109, p. 104-110 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Clinical staging of Fibrodysplasia Ossificans Progressiva (FOP)

Pignolo, R. & Kaplan, F. S., Apr 1 2018, In : Bone. 109, p. 111-114 4 p.

Research output: Contribution to journalArticle

7 Scopus citations

Diagnosis and management of pseudohypoparathyroidism and related disorders: First international Consensus Statement

Mantovani, G., Bastepe, M., Monk, D., De Sanctis, L., Thiele, S., Usardi, A., Ahmed, S. F., Bufo, R., Choplin, T., De Filippo, G., Devernois, G., Eggermann, T., Elli, F. M., Freson, K., García Ramirez, A., Germain-Lee, E. L., Groussin, L., Hamdy, N., Hanna, P., Hiort, O. & 26 others, Jüppner, H., Kamenický, P., Knight, N., Kottler, M. L., Le Norcy, E., Lecumberri, B., Levine, M. A., Mäkitie, O., Martin, R., Martos-Moreno, G. Á., Minagawa, M., Murray, P., Pereda, A., Pignolo, R., Rejnmark, L., Rodado, R., Rothenbuhler, A., Saraff, V., Shoemaker, A. H., Shore, E. M., Silve, C., Turan, S., Woods, P., Carola Zillikens, M., De Nanclares, G. P. & Linglart, A., Aug 1 2018, In : Nature Reviews Endocrinology. 14, 8, p. 476-500 25 p.

Research output: Contribution to journalArticle

33 Scopus citations

Early clinical observations on the use of imatinib mesylate in FOP: A report of seven cases

Kaplan, F. S., Andolina, J. R., Adamson, P. C., Teachey, D. T., Finklestein, J. Z., Ebb, D. H., Whitehead, B., Jacobs, B., Siegel, D. M., Keen, R., Hsiao, E. & Pignolo, R. J., Apr 2018, In : Bone. 109, p. 276-280 5 p.

Research output: Contribution to journalArticle

14 Scopus citations

ECSIT links TLR and BMP signaling in FOP connective tissue progenitor cells

Wang, H., Behrens, E. M., Pignolo, R. & Kaplan, F. S., Apr 1 2018, In : Bone. 109, p. 201-209 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Heterotopic Ossification: The Keys to the Kingdom

Kaplan, F. S., Pignolo, R. & Shore, E. M., Apr 1 2018, In : Bone. 109, p. 1-2 2 p.

Research output: Contribution to journalEditorial

Histopathology of periarticular non-hereditary heterotopic ossification

Foley, K. L., Hebela, N., Keenan, M. A. & Pignolo, R., Apr 1 2018, In : Bone. 109, p. 65-70 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

How Good Intentions Contributed to Bad Outcomes: The Opioid Crisis

Rummans, T. A., Burton, M. C. & Dawson, N. L., Mar 1 2018, In : Mayo Clinic Proceedings. 93, 3, p. 344-350 7 p.

Research output: Contribution to journalReview article

36 Scopus citations

Imaging assessment of fibrodysplasia ossificans progressiva: Qualitative, quantitative and questionable

Al Mukaddam, M., Rajapakse, C. S., Pignolo, R. J., Kaplan, F. S. & Smith, S. E., Apr 2018, In : Bone. 109, p. 147-152 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Immunotherapy-induced colitis: An emerging problem for the hospitalist

Marin-Acevedo, J. A., Harris, D. M. & Burton, M. C., Jun 2018, In : Journal of hospital medicine. 13, 6, p. 413-418 6 p.

Research output: Contribution to journalReview article

6 Scopus citations

Implementation of a new guideline and educational sessions to reduce low-value continuous pulse oximetry among hospitalized patients

Helgeson, S. A., Koop, A. H., Harrison, A. M., Ray, J. C., Shaughnessy, G. F., Brett, C. L., Cornell, L. F., Bowman, C. L. & Burton, M. C., Feb 1 2018, In : Southern Medical Journal. 111, 2, p. 87-92 6 p.

Research output: Contribution to journalArticle