Health Sciences Research

Research Output 1992 2019

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2019

Accurate patient-specific machine learning models of glioblastoma invasion using transfer learning

Hu, L. S., Yoon, H., Eschbacher, J. M., Baxter, L. C., Dueck, A., Nespodzany, A., Smith, K. A., Nakaji, P., Xu, Y., Wang, L., Karis, J. P., Hawkins-Daarud, A. J., Singleton, K. W., Jackson, P. R., Anderies, B. J., Bendok, B., Zimmerman, R. S., Quarles, C., Porter-Umphrey, A. B., Mrugala, M. M. & 11 others, Sharma, A., Hoxworth, J. M., Sattur, M. G., Sanai, N., Koulemberis, P. E., Krishna, C., Mitchell, J. R., Wu, T., Tran, N., Swanson, K. & Li, J., Jan 1 2019, In : American Journal of Neuroradiology. 40, 3, p. 418-425 8 p.

Research output: Contribution to journalArticle

Open Access
Glioblastoma
Cell Count
Neoplasms
Image-Guided Biopsy
Diffusion Tensor Imaging
1 Citation (Scopus)

Analytical Methods for Observational Data to Generate Hypotheses and Inform Clinical Decisions

DeWees, T., Vargas, C. E., Golafshar, M. A., Harmsen, W. S. & Dueck, A., Jan 1 2019, In : Seminars in Radiation Oncology.

Research output: Contribution to journalArticle

Observational Studies
Randomized Controlled Trials
Research Personnel
Costs and Cost Analysis
Research
1 Citation (Scopus)

Association analyses identify 31 new risk loci for colorectal cancer susceptibility

the PRACTICAL consortium, Dec 1 2019, In : Nature communications. 10, 1, 2154.

Research output: Contribution to journalArticle

Open Access
loci
Colorectal Neoplasms
Genes
cancer
magnetic permeability
Open Access
Apolipoprotein E4
Genotype
hard labor
Independent Living
manual labor

Brain-Derived Neurotrophic Factor and Its Associations with Metabolism and Physical Activity in a Latino Sample

Fonseca-Portilla, R., Krell-Roesch, J., Shaibi, G. Q., Caselli, R. J., Mandarino, L. J., Zhang, N., Hentz, J. G., Coletta, D. K., De Filippis, E. A., Dawit, S. & Geda, Y. E., Mar 1 2019, In : Metabolic Syndrome and Related Disorders. 17, 2, p. 75-80 6 p.

Research output: Contribution to journalArticle

Open Access
Brain-Derived Neurotrophic Factor
Hispanic Americans
Exercise
Body Mass Index
Serum
1 Citation (Scopus)

Brain MR radiomics to differentiate cognitive disorders

Alzheimer’s Disease Neuroimaging Initiative, Jul 1 2019, In : Journal of Neuropsychiatry and Clinical Neurosciences. 31, 3, p. 210-219 10 p.

Research output: Contribution to journalArticle

Magnetic Resonance Spectroscopy
Dementia
Alzheimer Disease
Brain
Discriminant Analysis
3 Citations (Scopus)

Can Methods Developed for Interpreting Group-level Patient-reported Outcome Data be Applied to Individual Patient Management?

King, M. T., Dueck, A. & Revicki, D. A., May 1 2019, In : Medical Care. 57, p. S38-S45

Research output: Contribution to journalArticle

Decision Making
Patient Reported Outcome Measures
Qualitative Research
Calibration
Reference Values

Clonal analyses of refractory testicular germ cell tumors

Barrett, M., Lenkiewicz, E., Malasi, S., Stanton, M., Slack, J. L., Andrews, P., Pagliaro, L. & Bryce, A. H., Mar 1 2019, In : PloS one. 14, 3, e0213815.

Research output: Contribution to journalArticle

Open Access
Refractory materials
Tumors
germ cells
Cells
neoplasms
1 Citation (Scopus)

Cortical β-amyloid burden, neuropsychiatric symptoms, and cognitive status: the Mayo Clinic Study of Aging

Krell-Roesch, J., Vassilaki, M., Mielke, M. M., Kremers, W. K., Lowe, V., Vemuri, P. D., Machulda, M. M., Christianson, T. J., Syrjanen, J. A., Stokin, G. B., Butler, L. M., Traber, M., Jack, C. R. J., Knopman, D. S., Roberts, R. O., Petersen, R. C. & Geda, Y. E., Dec 1 2019, In : Translational psychiatry. 9, 1, 123.

Research output: Contribution to journalArticle

Open Access
Neurobehavioral Manifestations
Amyloid
Equipment and Supplies
Anxiety
Cognitive Dysfunction
12 Citations (Scopus)

Discovery of common and rare genetic risk variants for colorectal cancer

Huyghe, J. R., Bien, S. A., Harrison, T. A., Kang, H. M., Chen, S., Schmit, S. L., Conti, D. V., Qu, C., Jeon, J., Edlund, C. K., Greenside, P., Wainberg, M., Schumacher, F. R., Smith, J. D., Levine, D. M., Nelson, S. C., Sinnott-Armstrong, N. A., Albanes, D., Alonso, M. H., Anderson, K. & 179 others, Arnau-Collell, C., Arndt, V., Bamia, C., Banbury, B. L., Baron, J. A., Berndt, S. I., Bézieau, S., Bishop, D. T., Boehm, J., Boeing, H., Brenner, H., Brezina, S., Buch, S., Buchanan, D. D., Burnett-Hartman, A., Butterbach, K., Caan, B. J., Campbell, P. T., Carlson, C. S., Castellví-Bel, S., Chan, A. T., Chang-Claude, J., Chanock, S. J., Chirlaque, M. D., Cho, S. H., Connolly, C. M., Cross, A. J., Cuk, K., Curtis, K. R., de la Chapelle, A., Doheny, K. F., Duggan, D., Easton, D. F., Elias, S. G., Elliott, F., English, D. R., Feskens, E. J. M., Figueiredo, J. C., Fischer, R., FitzGerald, L. M., Forman, D., Gala, M., Gallinger, S., Gauderman, W. J., Giles, G. G., Gillanders, E., Gong, J., Goodman, P. J., Grady, W. M., Grove, J. S., Gsur, A., Gunter, M. J., Haile, R. W., Hampe, J., Hampel, H., Harlid, S., Hayes, R. B., Hofer, P., Hoffmeister, M., Hopper, J. L., Hsu, W. L., Huang, W. Y., Hudson, T. J., Hunter, D. J., Ibañez-Sanz, G., Idos, G. E., Ingersoll, R., Jackson, R. D., Jacobs, E. J., Jenkins, M. A., Joshi, A. D., Joshu, C. E., Keku, T. O., Key, T. J., Kim, H. R., Kobayashi, E., Kolonel, L. N., Kooperberg, C., Kühn, T., Küry, S., Kweon, S. S., Larsson, S. C., Laurie, C. A., Le Marchand, L., Leal, S. M., Lee, S. C., Lejbkowicz, F., Lemire, M., Li, C. I., Li, L., Lieb, W., Lin, Y., Lindblom, A., Lindor, N. M., Ling, H., Louie, T. L., Männistö, S., Markowitz, S. D., Martín, V., Masala, G., McNeil, C. E., Melas, M., Milne, R. L., Moreno, L., Murphy, N., Myte, R., Naccarati, A., Newcomb, P. A., Offit, K., Ogino, S., Onland-Moret, N. C., Pardini, B., Parfrey, P. S., Pearlman, R., Perduca, V., Pharoah, P. D. P., Pinchev, M., Platz, E. A., Prentice, R. L., Pugh, E., Raskin, L., Rennert, G., Rennert, H. S., Riboli, E., Rodríguez-Barranco, M., Romm, J., Sakoda, L. C., Schafmayer, C., Schoen, R. E., Seminara, D., Shah, M., Shelford, T., Shin, M. H., Shulman, K., Sieri, S., Slattery, M. L., Southey, M. C., Stadler, Z. K., Stegmaier, C., Su, Y. R., Tangen, C. M., Thibodeau, S. N., Thomas, D. C., Thomas, S. S., Toland, A. E., Trichopoulou, A., Ulrich, C. M., Van Den Berg, D. J., van Duijnhoven, F. J. B., Van Guelpen, B., van Kranen, H., Vijai, J., Visvanathan, K., Vodicka, P., Vodickova, L., Vymetalkova, V., Weigl, K., Weinstein, S. J., White, E., Win, A. K., Wolf, C. R., Wolk, A., Woods, M. O., Wu, A. H., Zaidi, S. H., Zanke, B. W., Zhang, Q., Zheng, W., Scacheri, P. C., Potter, J. D., Bassik, M. C., Kundaje, A., Casey, G., Moreno, V., Abecasis, G. R., Nickerson, D. A., Gruber, S. B., Hsu, L. & Peters, U., Jan 1 2019, In : Nature Genetics. 51, 1, p. 76-87 12 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Long Noncoding RNA
Preclinical Drug Evaluations
Genome-Wide Association Study
Haplotypes

Dosimetric comparison of distal esophageal carcinoma plans for patients treated with small-spot intensity-modulated proton versus volumetric-modulated arc therapies

Liu, C., Bhangoo, R. S., Sio, T. T., Yu, N. Y., Shan, J., Chiang, J. S., Ding, J. X., Rule, W. G., Korte, S., Lara, P., Ding, X., Bues, M., Hu, Y., DeWees, T., Ashman, J. B. & Liu, W., Jul 1 2019, In : Journal of applied clinical medical physics. 20, 7, p. 15-27 13 p.

Research output: Contribution to journalArticle

Open Access
Proton Therapy
Intensity-Modulated Radiotherapy
Protons
therapy
arcs

Effectiveness of postoperative radiotherapy after radical cystectomy for locally advanced bladder cancer

Fischer-Valuck, B. W., Michalski, J. M., Mitra, N., Christodouleas, J. P., DeWees, T., Kim, E., Smith, Z. L., Andriole, G. L., Arora, V., Bullock, A., Carmona, R., Figenshau, R. S., Grubb, R. L., Guzzo, T. J., Knoche, E. M., Malkowicz, S. B., Mamtani, R., Pachynski, R. K., Roth, B. J., Zaghloul, M. S. & 2 others, Gay, H. A. & Baumann, B. C., Jul 1 2019, In : Cancer medicine. 8, 8, p. 3698-3709 12 p.

Research output: Contribution to journalArticle

Open Access
Cystectomy
Urinary Bladder Neoplasms
Radiotherapy
Survival
Databases

Enhanced DNA repair and genomic stability identify a novel HIV-related diffuse large B-cell lymphoma signature

Maguire, A., Chen, X., Wisner, L., Malasi, S., Ramsower, C., Kendrick, S., Barrett, M., Glinsmann-Gibson, B., McGrath, M. & Rimsza, L., Jan 1 2019, In : International Journal of Cancer.

Research output: Contribution to journalArticle

Lymphoma, Large B-Cell, Diffuse
Genomic Instability
DNA Repair
HIV
Germinal Center
Dementia
Lewy Body Disease
Alzheimer Disease
Frontotemporal Dementia
1 Citation (Scopus)

Exploring the spatiotemporal genetic heterogeneity in metastatic lung adenocarcinoma using a nuclei flow-sorting approach

Lorber, T., Andor, N., Dietsche, T., Perrina, V., Juskevicius, D., Pereira, K., Greer, S. U., Krause, A., Müller, D. C., Savic Prince, S., Lardinois, D., Barrett, M., Ruiz, C. & Bubendorf, L., Jan 1 2019, (Accepted/In press) In : Journal of Pathology.

Research output: Contribution to journalArticle

Genetic Heterogeneity
Neoplasms
Mutation
Neoplasm Metastasis
Chromosomal Instability

Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer

Bien, S. A., Su, Y. R., Conti, D. V., Harrison, T. A., Qu, C., Guo, X., Lu, Y., Albanes, D., Auer, P. L., Banbury, B. L., Berndt, S. I., Bézieau, S., Brenner, H., Buchanan, D. D., Caan, B. J., Campbell, P. T., Carlson, C. S., Chan, A. T., Chang-Claude, J., Chen, S. & 58 others, Connolly, C. M., Easton, D. F., Feskens, E. J. M., Gallinger, S., Giles, G. G., Gunter, M. J., Hampe, J., Huyghe, J. R., Hoffmeister, M., Hudson, T. J., Jacobs, E. J., Jenkins, M. A., Kampman, E., Kang, H. M., Kühn, T., Küry, S., Lejbkowicz, F., Le Marchand, L., Milne, R. L., Li, L., Li, C. I., Lindblom, A., Lindor, N. M., Martín, V., McNeil, C. E., Melas, M., Moreno, V., Newcomb, P. A., Offit, K., Pharaoh, P. D. P., Potter, J. D., Qu, C., Riboli, E., Rennert, G., Sala, N., Schafmayer, C., Scacheri, P. C., Schmit, S. L., Severi, G., Slattery, M. L., Smith, J. D., Trichopoulou, A., Tumino, R., Ulrich, C. M., van Duijnhoven, F. J. B., Van Guelpen, B., Weinstein, S. J., White, E., Wolk, A., Woods, M. O., Wu, A. H., Abecasis, G. R., Casey, G., Nickerson, D. A., Gruber, S. B., Hsu, L., Zheng, W. & Peters, U., Apr 1 2019, In : Human genetics. 138, 4, p. 307-326 20 p.

Research output: Contribution to journalArticle

Open Access
Colorectal Neoplasms
Gene Expression
Genome-Wide Association Study
Transcriptome
Colon

How to Avoid Becoming Easy Prey for "Predatory" Journals and Why It Matters

Gades, N. M. & Toth, L. A., May 1 2019, In : Comparative medicine. 69, 3, p. 164-166 3 p.

Research output: Contribution to journalArticle

Impact of High-Molecular-Risk Mutations on Transplantation Outcomes in Patients with Myelofibrosis

Tamari, R., Rapaport, F., Zhang, N., McNamara, C., Kuykendall, A., Sallman, D. A., Komrokji, R., Arruda, A., Najfeld, V., Sandy, L., Medina, J., Litvin, R., Famulare, C. A., Patel, M. A., Maloy, M., Castro-Malaspina, H., Giralt, S. A., Weinberg, R. S., Mascarenhas, J. O., Mesa, R. & 6 others, Rondelli, D., Dueck, A., Levine, R. L., Gupta, V., Hoffman, R. & Rampal, R. K., Jun 1 2019, In : Biology of Blood and Marrow Transplantation. 25, 6, p. 1142-1151 10 p.

Research output: Contribution to journalArticle

Primary Myelofibrosis
Transplantation
Mutation
Hematopoietic Stem Cell Transplantation
Survival
3 Citations (Scopus)

Improving Benefit-harm Assessment of Therapies from the Patient Perspective: OMERACT premeeting toward consensus on core sets for randomized controlled trials

Andersen, K. M., Cheah, J. T. L., March, L., Bartlett, S. J., Beaton, D., Bingham, C. O., Brooks, P. M., Christensen, R., Conaghan, P. G., D’Agostino, M. A., De Wit, M., Dueck, A., Goodman, S. M., Grosskleg, S., Hill, C. L., Howell, M., Mackie, S. L., Richards, B., Shea, B., Singh, J. A. & 4 others, Strand, V., Tugwell, P., Wells, G. A. & Simon, L. S., Aug 1 2019, In : Journal of Rheumatology. 46, 8, p. 1053-1058 6 p.

Research output: Contribution to journalArticle

Patient Satisfaction
Randomized Controlled Trials
Rheumatology
Safety
Therapeutics
2 Citations (Scopus)

Lack of association between screening interval and cancer stage in Lynch syndrome may be accounted for by over-diagnosis; A prospective Lynch syndrome database report

Seppälä, T. T., Ahadova, A., Dominguez-Valentin, M., Macrae, F., Evans, D. G., Therkildsen, C., Sampson, J., Scott, R., Burn, J., Möslein, G., Bernstein, I., Holinski-Feder, E., Pylvänäinen, K., Renkonen-Sinisalo, L., Lepistö, A., Lautrup, C. K., Lindblom, A., Plazzer, J. P., Winship, I., Tjandra, D. & 37 others, Katz, L. H., Aretz, S., Hüneburg, R., Holzapfel, S., Heinimann, K., Valle, A. D., Neffa, F., Gluck, N., De Vos Tot Nederveen Cappel, W. H., Vasen, H., Morak, M., Steinke-Lange, V., Engel, C., Rahner, N., Schmiegel, W., Vangala, D., Thomas, H., Green, K., Lalloo, F., Crosbie, E. J., Hill, J., Capella, G., Pineda, M., Navarro, M., Blanco, I., Ten Broeke, S., Nielsen, M., Ljungmann, K., Nakken, S., Lindor, N. M., Frayling, I., Hovig, E., Sunde, L., Kloor, M., Mecklin, J. P., Kalager, M. & Møller, P., Feb 28 2019, In : Hereditary Cancer in Clinical Practice. 17, 1, 8.

Research output: Contribution to journalArticle

Open Access
Hereditary Nonpolyposis Colorectal Neoplasms
Colonoscopy
Early Detection of Cancer
DNA Mismatch Repair
Databases
1 Citation (Scopus)

Multi-Institutional Validation of a Knowledge-Based Planning Model for Patients Enrolled in RTOG 0617: Implications for Plan Quality Controls in Cooperative Group Trials

Kavanaugh, J. A., Holler, S., DeWees, T., Robinson, C. G., Bradley, J. D., Iyengar, P., Higgins, K. A., Mutic, S. & Olsen, L. A., Jan 1 2019, (Accepted/In press) In : Practical Radiation Oncology.

Research output: Contribution to journalArticle

Radiation Oncology
Quality Control
Radiotherapy
Lung
Clinical Trials
11 Citations (Scopus)

Novel common genetic susceptibility loci for colorectal cancer

Schmit, S. L., Edlund, C. K., Schumacher, F. R., Gong, J., Harrison, T. A., Huyghe, J. R., Qu, C., Melas, M., Van Den Berg, D. J., Wang, H., Tring, S., Plummer, S. J., Albanes, D., Alonso, M. H., Amos, C. I., Anton, K., Aragaki, A. K., Arndt, V., Barry, E. L., Berndt, S. I. & 163 others, Bezieau, S., Bien, S., Bloomer, A., Boehm, J., Boutron-Ruault, M. C., Brenner, H., Brezina, S., Buchanan, D. D., Butterbach, K., Caan, B. J., Campbell, P. T., Carlson, C. S., Castelao, J. E., Chan, A. T., Chang-Claude, J., Chanock, S. J., Cheng, I., Cheng, Y. W., Chin, L. S., Church, J. M., Church, T., Coetzee, G. A., Cotterchio, M., Correa, M. C., Curtis, K. R., Duggan, D., Easton, D. F., English, D., Feskens, E. J. M., Fischer, R., FitzGerald, L. M., Fortini, B. K., Fritsche, L. G., Fuchs, C. S., Gago-Dominguez, M., Gala, M., Gallinger, S. J., Gauderman, W. J., Giles, G. G., Giovannucci, E. L., Gogarten, S. M., Gonzalez-Villalpando, C., Gonzalez-Villalpando, E. M., Grady, W. M., Greenson, J. K., Gsur, A., Gunter, M., Haiman, C. A., Hampe, J., Harlid, S., Harju, J. F., Hayes, R. B., Hofer, P., Hoffmeister, M., Hopper, J. L., Huang, S. C., Huerta, J. M., Hudson, T. J., Hunter, D. J., Idos, G. E., Iwasaki, M., Jackson, R. D., Jacobs, E. J., Jee, S. H., Jenkins, M. A., Jia, W. H., Jiao, S., Joshi, A. D., Kolonel, L. N., Kono, S., Kooperberg, C., Krogh, V., Kuehn, T., Küry, S., LaCroix, A., Laurie, C. A., Lejbkowicz, F., Lemire, M., Lenz, H. J., Levine, D., Li, C. I., Li, L., Lieb, W., Lin, Y., Lindor, N. M., Liu, Y. R., Loupakis, F., Lu, Y., Luh, F., Ma, J., Mancao, C., Manion, F. J., Markowitz, S. D., Martin, V., Matsuda, K., Matsuo, K., McDonnell, K. J., McNeil, C. E., Milne, R., Molina, A. J., Mukherjee, B., Murphy, N., Newcomb, P. A., Offit, K., Omichessan, H., Palli, D., Paredes Cotoré, J. P., Pérez-Mayoral, J., Pharoah, P. D., Potter, J. D., Qu, C., Raskin, L., Rennert, G., Rennert, H. S., Riggs, B. M., Schafmayer, C., Schoen, R. E., Sellers, T. A., Seminara, D., Severi, G., Shi, W., Shibata, D., Shu, X. O., Siegel, E. M., Slattery, M. L., Southey, M., Stadler, Z. K., Stern, M. C., Stintzing, S., Taverna, D., Thibodeau, S. N., Thomas, D. C., Trichopoulou, A., Tsugane, S., Ulrich, C. M., Van Duijnhoven, F. J. B., Van Guelpan, B., Vijai, J., Virtamo, J., Weinstein, S. J., White, E., Win, A. K., Wolk, A., Woods, M., Wu, A. H., Wu, K., Xiang, Y. B., Yen, Y., Zanke, B. W., Zeng, Y. X., Zhang, B., Zubair, N., Kweon, S. S., Figueiredo, J. C., Zheng, W., Le Marchand, L., Lindblom, A., Moreno, V., Peters, U., Casey, G., Hsu, L., Conti, D. V. & Gruber, S. B., Jan 1 2019, In : Journal of the National Cancer Institute. 111, 2, p. 146-157 12 p.

Research output: Contribution to journalArticle

Genetic Loci
Genetic Predisposition to Disease
Colorectal Neoplasms
Genome-Wide Association Study
Confidence Intervals

Online yoga in myeloproliferative neoplasm patients: Results of a randomized pilot trial to inform future research

Huberty, J., Eckert, R., Dueck, A., Kosiorek, H., Larkey, L., Gowin, K. & Mesa, R., Jun 7 2019, In : BMC Complementary and Alternative Medicine. 19, 1, 121.

Research output: Contribution to journalArticle

Open Access
Yoga
Neoplasms
Sleep
Anxiety
Tumor Necrosis Factor-alpha
1 Citation (Scopus)

Oral idasanutlin in patients with polycythemia vera

Mascarenhas, J., Lu, M., Kosiorek, H., Virtgaym, E., Xia, L., Sandy, L., Mesa, R., Petersen, B., Farnoud, N., Najfeld, V., Rampal, R., Dueck, A. & Hoffman, R., Aug 8 2019, In : Blood. 134, 6, p. 525-533 9 p.

Research output: Contribution to journalArticle

Polycythemia Vera
Essential Thrombocythemia
Interferons
Toxicity
Chemical activation
4 Citations (Scopus)

Patient free text reporting of symptomatic adverse events in cancer clinical research using the National Cancer Institute's Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE)

Chung, A. E., Shoenbill, K., Mitchell, S. A., Dueck, A., Schrag, D., Bruner, D. W., Minasian, L. M., St Germain, D., O'Mara, A. M., Baumgartner, P., Rogak, L. J., Abernethy, A. P., Griffin, A. C. & Basch, E. M., Feb 20 2019, In : Journal of the American Medical Informatics Association. 26, 4, p. 276-285 10 p.

Research output: Contribution to journalArticle

National Cancer Institute (U.S.)
Terminology
Medical Dictionaries
Research
Neoplasms

Phase II trial of Lestaurtinib, a JAK2 inhibitor, in patients with myelofibrosis

Mascarenhas, J., Baer, M. R., Kessler, C., Hexner, E., Tremblay, D., Price, L., Sandy, L., Weinberg, R., Pahl, H., Silverman, L. R., Goldberg, J. D., Kosiorek, H., Dueck, A. & Hoffman, R., Jan 1 2019, (Accepted/In press) In : Leukemia and Lymphoma.

Research output: Contribution to journalArticle

Primary Myelofibrosis
lestaurtinib
1 Citation (Scopus)

Predicting Progression to Mild Cognitive Impairment

Petersen, R. C., Lundt, E. S., Therneau, T. M., Weigand, S. D., Knopman, D. S., Mielke, M. M., Roberts, R. O., Lowe, V., Machulda, M. M., Kremers, W. K., Geda, Y. E. & Jack, C. R. J., Jan 1 2019, In : Annals of Neurology. 85, 1, p. 155-160 6 p.

Research output: Contribution to journalArticle

Biomarkers
Amyloid
Cognitive Dysfunction
Alzheimer Disease
Population

Prevalence of ideal cardiovascular health in a Central European community: results from the Kardiovize Brno 2030 Project

Medina-Inojosa, J. R., Vinciguerra, M., Maugeri, A., Kunzova, S., Sochor, O., Movsisyan, N., Geda, Y. E., Stokin, G. B. & Lopez-Jimenez, F., Jan 1 2019, In : European Journal of Preventive Cardiology.

Research output: Contribution to journalArticle

European Union
Health

Quantity and quality of mental activities and the risk of incident mild cognitive impairment

Krell-Roesch, J., Syrjanen, J. A., Vassilaki, M., Machulda, M. M., Mielke, M. M., Knopman, D. S., Kremers, W. K., Petersen, R. C. & Geda, Y. E., Aug 6 2019, In : Neurology. 93, 6, p. e548-e558

Research output: Contribution to journalArticle

Open Access
Independent Living
Cognitive Dysfunction
Reading
Cohort Studies
Prospective Studies

Risks of Colorectal Cancer and Cancer-Related Mortality in Familial Colorectal Cancer Type X and Lynch Syndrome Families

Choi, Y. H., Lakhal-Chaieb, L., Kröl, A., Yu, B., Buchanan, D., Ahnen, D., Le Marchand, L., Newcomb, P. A., Win, A. K., Jenkins, M., Lindor, N. M. & Briollais, L., Jul 1 2019, In : Journal of the National Cancer Institute. 111, 7, p. 675-683 9 p., djy159.

Research output: Contribution to journalArticle

Hereditary Nonpolyposis Colorectal Neoplasms
Colorectal Neoplasms
Mortality
Neoplasms
Confidence Intervals
4 Citations (Scopus)

Shared heritability and functional enrichment across six solid cancers

Jiang, X., Finucane, H. K., Schumacher, F. R., Schmit, S. L., Tyrer, J. P., Han, Y., Michailidou, K., Lesseur, C., Kuchenbaecker, K. B., Dennis, J., Conti, D. V., Casey, G., Gaudet, M. M., Huyghe, J. R., Albanes, D., Aldrich, M. C., Andrew, A. S., Andrulis, I. L., Anton-Culver, H., Antoniou, A. C. & 313 others, Antonenkova, N. N., Arnold, S. M., Aronson, K. J., Arun, B. K., Bandera, E. V., Barkardottir, R. B., Barnes, D. R., Batra, J., Beckmann, M. W., Benitez, J., Benlloch, S., Berchuck, A., Berndt, S. I., Bickeböller, H., Bien, S. A., Blomqvist, C., Boccia, S., Bogdanova, N. V., Bojesen, S. E., Bolla, M. K., Brauch, H., Brenner, H., Brenton, J. D., Brook, M. N., Brunet, J., Brunnström, H., Buchanan, D. D., Burwinkel, B., Butzow, R., Cadoni, G., Caldés, T., Caligo, M. A., Campbell, I., Campbell, P. T., Cancel-Tassin, G., Cannon-Albright, L., Campa, D., Caporaso, N., Carvalho, A. L., Chan, A. T., Chang-Claude, J., Chanock, S. J., Chen, C., Christiani, D. C., Claes, K. B. M., Claessens, F., Clements, J., Collée, J. M., Correa, M. C., Couch, F. J., Cox, A., Cunningham, J. M., Cybulski, C., Czene, K., Daly, M. B., deFazio, A., Devilee, P., Diez, O., Gago-Dominguez, M., Donovan, J. L., Dörk, T., Duell, E. J., Dunning, A. M., Dwek, M., Eccles, D. M., Edlund, C. K., Edwards, D. R. V., Ellberg, C., Evans, D. G., Fasching, P. A., Ferris, R. L., Liloglou, T., Figueiredo, J. C., Fletcher, O., Fortner, R. T., Fostira, F., Franceschi, S., Friedman, E., Gallinger, S. J., Ganz, P. A., Garber, J., García-Sáenz, J. A., Gayther, S. A., Giles, G. G., Godwin, A. K., Goldberg, M. S., Goldgar, D. E., Goode, E. L., Goodman, M. T., Goodman, G., Grankvist, K., Greene, M. H., Gronberg, H., Gronwald, J., Guénel, P., Håkansson, N., Hall, P., Hamann, U., Hamdy, F. C., Hamilton, R. J., Hampe, J., Haugen, A., Heitz, F., Herrero, R., Hillemanns, P., Hoffmeister, M., Høgdall, E., Hong, Y. C., Hopper, J. L., Houlston, R., Hulick, P. J., Hunter, D. J., Huntsman, D. G., Idos, G., Imyanitov, E. N., Ingles, S. A., Isaacs, C., Jakubowska, A., James, P., Jenkins, M. A., Johansson, M., Johansson, M., John, E. M., Joshi, A. D., Kaneva, R., Karlan, B. Y., Kelemen, L. E., Kühl, T., Khaw, K. T., Khusnutdinova, E., Kibel, A. S., Kiemeney, L. A., Kim, J., Kjaer, S. K., Knight, J. A., Kogevinas, M., Kote-Jarai, Z., Koutros, S., Kristensen, V. N., Kupryjanczyk, J., Lacko, M., Lam, S., Lambrechts, D., Landi, M. T., Lazarus, P., Le, N. D., Lee, E., Lejbkowicz, F., Lenz, H. J., Leslie, G., Lessel, D., Lester, J., Levine, D. A., Li, L., Li, C. I., Lindblom, A., Lindor, N. M., Liu, G., Loupakis, F., Lubiński, J., Maehle, L., Maier, C., Mannermaa, A., Marchand, L. L., Margolin, S., May, T., McGuffog, L., Meindl, A., Middha, P., Miller, A., Milne, R. L., MacInnis, R. J., Modugno, F., Montagna, M., Moreno, V., Moysich, K. B., Mucci, L., Muir, K., Mulligan, A. M., Nathanson, K. L., Neal, D. E., Ness, A. R., Neuhausen, S. L., Nevanlinna, H., Newcomb, P. A., Newcomb, L. F., Nielsen, F. C., Nikitina-Zake, L., Nordestgaard, B. G., Nussbaum, R. L., Offit, K., Olah, E., Olama, A. A. A., Olopade, O. I., Olshan, A. F., Olsson, H., Osorio, A., Pandha, H., Park, J. Y., Pashayan, N., Parsons, M. T., Pejovic, T., Penney, K. L., Peters, W. H. M., Phelan, C. M., Phipps, A. I., Plaseska-Karanfilska, D., Pring, M., Prokofyeva, D., Radice, P., Stefansson, K., Ramus, S. J., Raskin, L., Rennert, G., Rennert, H. S., van Rensburg, E. J., Riggan, M. J., Risch, H. A., Risch, A., Roobol, M. J., Rosenstein, B. S., Rossing, M. A., De Ruyck, K., Saloustros, E., Sandler, D. P., Sawyer, E. J., Schabath, M. B., Schleutker, J., Schmidt, M. K., Setiawan, V. W., Shen, H., Siegel, E. M., Sieh, W., Singer, C. F., Slattery, M. L., Sorensen, K. D., Southey, M. C., Spurdle, A. B., Stanford, J. L., Stevens, V. L., Stintzing, S., Stone, J., Sundfeldt, K., Sutphen, R., Swerdlow, A. J., Tajara, E. H., Tangen, C. M., Tardon, A., Taylor, J. A., Teare, M. D., Teixeira, M. R., Terry, M. B., Terry, K. L., Thibodeau, S. N., Thomassen, M., Bjørge, L., Tischkowitz, M., Toland, A. E., Torres, D., Townsend, P. A., Travis, R. C., Tung, N., Tworoger, S. S., Ulrich, C. M., Usmani, N., Vachon, C. M., Van Nieuwenhuysen, E., Vega, A., Aguado-Barrera, M. E., Wang, Q., Webb, P. M., Weinberg, C. R., Weinstein, S., Weissler, M. C., Weitzel, J. N., West, C. M. L., White, E., Whittemore, A. S., Wichmann, H. E., Wiklund, F., Winqvist, R., Wolk, A., Woll, P., Woods, M., Wu, A. H., Wu, X., Yannoukakos, D., Zheng, W., Zienolddiny, S., Ziogas, A., Zorn, K. K., Lane, J. M., Saxena, R., Thomas, D., Hung, R. J., Diergaarde, B., McKay, J., Peters, U., Hsu, L., García-Closas, M., Eeles, R. A., Chenevix-Trench, G., Brennan, P. J., Haiman, C. A., Simard, J., Easton, D. F., Gruber, S. B., Pharoah, P. D. P., Price, A. L., Pasaniuc, B., Amos, C. I., Kraft, P. & Lindström, S., Dec 1 2019, In : Nature Communications. 10, 1, 431.

Research output: Contribution to journalArticle

cancer
Nucleic Acid Regulatory Sequences
Tumors
Neoplasms
Genes
Open Access
Comorbidity
Biomarkers
Alzheimer Disease
Medical Record Linkage
Logistic Models

Timing of Postoperative Radiotherapy in Surgically Treated HPV-Positive Oropharyngeal Squamous Cell Carcinoma

Townsend, M., DeWees, T., Gross, J., Daly, M., Gay, H., Thorstad, W. & Jackson, R. S., Jan 1 2019, In : Otolaryngology - Head and Neck Surgery (United States).

Research output: Contribution to journalArticle

Squamous Cell Carcinoma
Radiotherapy
Survival
Recurrence
Radiation
2018
3 Citations (Scopus)

Advanced forms of MPNs are accompanied by chromosomal abnormalities that lead to dysregulation of TP53

Marcellino, B. K., Hoffman, R., Tripodi, J., Lu, M., Kosiorek, H., Mascarenhas, J., Rampal, R. K., Dueck, A. & Najfeld, V., Dec 26 2018, In : Blood advances. 2, 24, p. 3581-3589 9 p.

Research output: Contribution to journalArticle

Chromosome Aberrations
Neoplasms
Proteins
Polycythemia Vera
Essential Thrombocythemia
1 Citation (Scopus)

Age and the Risk of Paclitaxel-Induced Neuropathy in Women with Early-Stage Breast Cancer (Alliance A151411): Results from 1,881 Patients from Cancer and Leukemia Group B (CALGB) 40101

Barginear, M., Dueck, A., Allred, J. B., Bunnell, C., Cohen, H. J., Freedman, R. A., Hurria, A., Kimmick, G., Le-Rademacher, J., Lichtman, S., Muss, H. B., Shulman, L. N., Sitiki Copur, M., Biggs, D., Ramaswamy, B., Lafky, J. M. & Jatoi, A., Jan 1 2018, (Accepted/In press) In : Oncologist.

Research output: Contribution to journalArticle

Paclitaxel
Leukemia
Breast Neoplasms
Neoplasms
Terminology
1 Citation (Scopus)

A molecular approach combined with American Thyroid Association classification better stratifies recurrence risk of classic histology papillary thyroid cancer

Lin, A. J., Samson, P., DeWees, T., Henke, L., Baranski, T., Schwarz, J., Pfeifer, J., Grigsby, P. & Markovina, S., Jan 1 2018, (Accepted/In press) In : Cancer Medicine.

Research output: Contribution to journalArticle

Histology
Recurrence
Peroxisome Proliferator-Activated Receptors
Neoplasms
Thyroid Gland

A Novel Combination of the mTORC1 Inhibitor Everolimus and the Immunomodulatory Drug Lenalidomide Produces Durable Responses in Patients With Heavily Pretreated Relapsed Lymphoma

Padrnos, L., Ernst, B., Dueck, A., Kosiorek, H. E., Ginos, B. F., Toro, A., Johnston, P. B., Habermann, T. M., Leis, J. F., Mikhael, J. R., Nowakowski, G. S., Colgan, J., Porrata, L., Ansell, S. M., Witzig, T. E. & Reeder, C., Jan 1 2018, (Accepted/In press) In : Clinical Lymphoma, Myeloma and Leukemia.

Research output: Contribution to journalArticle

Lymphoma
Pharmaceutical Preparations
Maximum Tolerated Dose
Neutropenia
Hodgkin Disease

Anticholinergic Medications and Cognitive Function in Late Midlife

Limback-Stokin, M. M., Krell-Roesch, J., Roesler, K., Hansen, A., Stonnington, C. M., Temkit, MH., Caselli, R. J. & Geda, Y. E., Jan 1 2018, In : Alzheimer Disease and Associated Disorders. 32, 3, p. 262-264 3 p.

Research output: Contribution to journalArticle

Cholinergic Antagonists
Cognition

A phase 2 study of rituximab, cyclophosphamide, bortezomib and dexamethasone (R-CyBorD) in relapsed low grade and mantle cell lymphoma

Sonbol, M. B., Hilal, T., Dueck, A., Rosenthal, A. C., Conley, C. R., Kosiorek, H. E., Ginos, B. F., Gano, K. M., Nichols, C. S., Leis, J. F., Johnston, P. B., Habermann, T. M., Northfelt, D. W., Bergsagel, P. L., Inwards, D. J., Witzig, T. E., Ansell, S. M. & Reeder, C. B., Jan 11 2018, (Accepted/In press) In : Leukemia and Lymphoma. p. 1-7 7 p.

Research output: Contribution to journalArticle

Mantle-Cell Lymphoma
Cyclophosphamide
Dexamethasone
Safety
Peripheral Nervous System Diseases
2 Citations (Scopus)

Applying social network analysis to evaluate implementation of a multisector population health collaborative that uses a bridging hub organization

Leppin, A. L., Okamoto, J., Organick, P. W., Thota, A. D., Barrera-Flores, F. J., Wieland, M. L., McCoy, R., Bonacci, R. P. & Montori, V. M., Nov 2 2018, In : Frontiers in Public Health. 6, NOV, 315.

Research output: Contribution to journalArticle

Social Support
Organizations
Health
Population
Delivery of Health Care
13 Citations (Scopus)

Assessment of the Clinical Relevance of BRCA2 Missense Variants by Functional and Computational Approaches

Guidugli, L., Shimelis, H., Masica, D. L., Pankratz, V. S., Lipton, G. B., Singh, N., Hu, C., Monteiro, A. N. A., Lindor, N. M., Goldgar, D. E., Karchin, R., Iversen, E. S. & Couch, F. J., Jan 1 2018, (Accepted/In press) In : American Journal of Human Genetics.

Research output: Contribution to journalArticle

Virulence
Homologous Recombination
Endophenotypes
Recombinational DNA Repair
DNA
2 Citations (Scopus)
Dementia
Alzheimer Disease
Biomarkers
Amyloid
Neuroimaging
1 Citation (Scopus)
genetic research
Genetic Research
Spouses
research results
spouse
13 Citations (Scopus)

Beyond maximum grade: modernising the assessment and reporting of adverse events in haematological malignancies

Thanarajasingam, G., Minasian, L. M., Baron, F., Cavalli, F., De Claro, R. A., Dueck, A., El-Galaly, T. C., Everest, N., Geissler, J., Gisselbrecht, C., Gribben, J., Horowitz, M., Ivy, S. P., Jacobson, C. A., Keating, A., Kluetz, P. G., Krauss, A., Kwong, Y. L., Little, R. F., Mahon, F. X. & 20 others, Matasar, M. J., Mateos, M. V., McCullough, K., Miller, R. S., Mohty, M., Moreau, P., Morton, L. M., Nagai, S., Rule, S., Sloan, J. A., Sonneveld, P., Thompson, C. A., Tzogani, K., van Leeuwen, F. E., Velikova, G., Villa, D., Wingard, J. R., Wintrich, S., Seymour, J. F. & Habermann, T. M., Jan 1 2018, (Accepted/In press) In : The Lancet Haematology.

Research output: Contribution to journalArticle

Hematologic Neoplasms
Neoplasms
Needs Assessment
Stem Cell Transplantation
B-Cell Lymphoma
2 Citations (Scopus)

Cabozantinib Versus Mitoxantrone-prednisone in Symptomatic Metastatic Castration-resistant Prostate Cancer: A Randomized Phase 3 Trial with a Primary Pain Endpoint

Basch, E. M., Scholz, M., de Bono, J. S., Vogelzang, N., de Souza, P., Marx, G., Vaishampayan, U., George, S., Schwarz, J. K., Antonarakis, E. S., O'Sullivan, J. M., Kalebasty, A. R., Chi, K. N., Dreicer, R., Hutson, T. E., Dueck, A., Bennett, A. V., Dayan, E., Mangeshkar, M., Holland, J. & 2 others, Weitzman, A. L. & Scher, H. I., Jan 1 2018, (Accepted/In press) In : European Urology.

Research output: Contribution to journalArticle

Mitoxantrone
Castration
Prednisone
Prostatic Neoplasms
Pain
8 Citations (Scopus)

Carbonyl emissions from a novel heated tobacco product (IQOS): Comparison with an e-cigarette and a tobacco cigarette

Farsalinos, K. E., Yannovits, N., Sarri, T., Voudris, V., Poulas, K. & Leischow, S. J., Jan 1 2018, (Accepted/In press) In : Addiction.

Research output: Contribution to journalArticle

Tobacco Products
Tobacco
2-butenal
Acrolein
Formaldehyde
3 Citations (Scopus)

Cohort Profile: The Colon Cancer Family Registry Cohort (CCFRC)

Colon Cancer Family Registry Cohort Investigators , Apr 1 2018, In : International Journal of Epidemiology. 47, 2

Research output: Contribution to journalArticle

disease treatment
cohort analysis
interdisciplinary approach
etiology
morbidity
2 Citations (Scopus)

Comprehensive annotation of BRCA1 and BRCA2 missense variants by functionally validated sequence-based computational prediction models

Hart, S., Hoskin, T., Shimelis, H., Moore, R. M., Feng, B., Thomas, A., Lindor, N. M., Polley, E., Goldgar, D. E., Iversen, E., Monteiro, A. N. A., Suman, V. J. & Couch, F. J., Jun 8 2018, (Accepted/In press) In : Genetics in Medicine. p. 1-10 10 p.

Research output: Contribution to journalArticle

Politics
Computer Simulation
Area Under Curve
BRCA2 Protein
Confidence Intervals

Current Approaches to Cancer Genetic Counseling Services for Spanish-Speaking Patients

Augusto, B., Kasting, M. L., Couch, F. J., Lindor, N. M. & Vadaparampil, S. T., Jun 7 2018, (Accepted/In press) In : Journal of Immigrant and Minority Health. p. 1-4 4 p.

Research output: Contribution to journalArticle

Genetic Services
Genetic Counseling
Hispanic Americans
Neoplasms
Communication Barriers
1 Citation (Scopus)

Defining Optimal Comorbidity Measures for Patients With Early-Stage Non-Small Cell Lung Cancer Treated With Stereotactic Body Radiation Therapy

DeWees, T., Nikitas, J., Rehman, S., Bradley, J. D., Robinson, C. G. & Roach, M. C., Jan 1 2018, (Accepted/In press) In : Practical Radiation Oncology.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Comorbidity
Radiotherapy
Survival
Age Groups