Health Sciences Research

Research Output 1992 2019

2014
22 Citations (Scopus)

DNA Glycosylases Involved in Base Excision Repair May Be Associated with Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

Osorio, A., Milne, R. L., Kuchenbaecker, K., Vaclová, T., Pita, G., Alonso, R., Peterlongo, P., Blanco, I., de la Hoya, M., Duran, M., Díez, O., Ramón y Cajal, T., Konstantopoulou, I., Martínez-Bouzas, C., Andrés Conejero, R., Soucy, P., McGuffog, L., Barrowdale, D., Lee, A., Arver, B. & 177 others, Rantala, J., Loman, N., Ehrencrona, H., Olopade, O. I., Beattie, M. S., Domchek, S. M., Nathanson, K., Rebbeck, T. R., Arun, B. K., Karlan, B. Y., Walsh, C., Lester, J., John, E. M., Whittemore, A. S., Daly, M. B., Southey, M., Hopper, J., Terry, M. B., Buys, S. S., Janavicius, R., Dorfling, C. M., van Rensburg, E. J., Steele, L., Neuhausen, S. L., Ding, Y. C., Hansen, T. V. O., Jønson, L., Ejlertsen, B., Gerdes, A. M., Infante, M., Herráez, B., Moreno, L. T., Weitzel, J. N., Herzog, J., Weeman, K., Manoukian, S., Peissel, B., Zaffaroni, D., Scuvera, G., Bonanni, B., Mariette, F., Volorio, S., Viel, A., Varesco, L., Papi, L., Ottini, L., Tibiletti, M. G., Radice, P., Yannoukakos, D., Garber, J., Ellis, S., Frost, D., Platte, R., Fineberg, E., Evans, G., Lalloo, F., Izatt, L., Eeles, R., Adlard, J., Davidson, R., Cole, T., Eccles, D., Cook, J., Hodgson, S., Brewer, C., Tischkowitz, M., Douglas, F., Porteous, M., Side, L., Walker, L., Morrison, P., Donaldson, A., Kennedy, J., Foo, C., Godwin, A. K., Schmutzler, R. K., Wappenschmidt, B., Rhiem, K., Engel, C., Meindl, A., Ditsch, N., Arnold, N., Plendl, H. J., Niederacher, D., Sutter, C., Wang-Gohrke, S., Steinemann, D., Preisler-Adams, S., Kast, K., Varon-Mateeva, R., Gehrig, A., Stoppa-Lyonnet, D., Sinilnikova, O. M., Mazoyer, S., Damiola, F., Poppe, B., Claes, K., Piedmonte, M., Tucker, K., Backes, F., Rodríguez, G., Brewster, W., Wakeley, K., Rutherford, T., Caldés, T., Nevanlinna, H., Aittomäki, K., Rookus, M. A., van Os, T. A. M., van der Kolk, L., de Lange, J. L., Meijers-Heijboer, H. E. J., van der Hout, A. H., van Asperen, C. J., Gómez Garcia, E. B., Hoogerbrugge, N., Collée, J. M., van Deurzen, C. H. M., van der Luijt, R. B., Devilee, P., Olah, E., Lázaro, C., Teulé, A., Menéndez, M., Jakubowska, A., Cybulski, C., Gronwald, J., Lubinski, J., Durda, K., Jaworska-Bieniek, K., Johannsson, O. T., Maugard, C., Montagna, M., Tognazzo, S., Teixeira, M. R., Healey, S., Olswold, C., Guidugli, L., Lindor, N. M., Slager, S. L., Szabo, C. I., Vijai, J., Robson, M., Kauff, N., Zhang, L., Rau-Murthy, R., Fink-Retter, A., Singer, C. F., Rappaport, C., Geschwantler Kaulich, D., Pfeiler, G., Tea, M. K., Berger, A., Phelan, C. M., Greene, M. H., Mai, P. L., Lejbkowicz, F., Andrulis, I., Mulligan, A. M., Glendon, G., Toland, A. E., Bojesen, A., Pedersen, I. S., Sunde, L., Thomassen, M., Kruse, T. A., Jensen, U. B., Friedman, E., Laitman, Y., Shimon, S. P., Simard, J., Easton, D. F., Offit, K., Couch, F. J., Chenevix-Trench, G., Antoniou, A. C. & Benitez, J., 2014, In : PLoS Genetics. 10, 4, e1004256.

Research output: Contribution to journalArticle

DNA Glycosylases
glycosylases
DNA repair
DNA Repair
repair
16 Citations (Scopus)

Does risk of endometrial cancer for women without a germline mutation in a DNA mismatch repair gene depend on family history of endometrial cancer or colorectal cancer?

Bharati, R., Jenkins, M. A., Lindor, N. M., Le Marchand, L., Gallinger, S., Haile, R. W., Newcomb, P. A., Hopper, J. L. & Win, A. K., 2014, In : Gynecologic Oncology. 133, 2, p. 287-292 6 p.

Research output: Contribution to journalArticle

DNA Mismatch Repair
Germ-Line Mutation
Endometrial Neoplasms
Colorectal Neoplasms
Genes
10 Citations (Scopus)

Dysplasia in ulcerative colitis as a predictor of unsuspected synchronous colorectal cancer

Murphy, J., Kalkbrenner, K. A., Pemberton, J. H., Landmann, R. G., Heppell, J. P., Young-Fadok, T. M. & Etzioni, D. A., 2014, In : Diseases of the Colon and Rectum. 57, 8, p. 993-998 6 p.

Research output: Contribution to journalArticle

Ulcerative Colitis
Colorectal Neoplasms
Neoplasms
Colectomy
Biopsy
17 Citations (Scopus)

EGFR expression is associated with decreased benefit from trastuzumab in the NCCTG N9831 (Alliance) trial.

Cheng, H., Ballman, K., Vassilakopoulou, M., Dueck, A., Reinholz, M. M., Tenner, K., Gralow, J., Hudis, C., Davidson, N. E., Fountzilas, G., McCullough, A. E., Chen, B., Psyrri, A., Rimm, D. L. & Perez, E. A., 2014, In : British Journal of Cancer. 111, 6, p. 1065-1071 7 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Neoplasms
Therapeutics
Drug Therapy
Breast Neoplasms
6 Citations (Scopus)

Family history of colorectal cancer is not associated with colorectal cancer survival regardless of microsatellite instability status

Phipps, A. I., Ahnen, D. J., Campbell, P. T., Win, A. K., Jenkins, M. A., Lindor, N. M., Gryfe, R., Potter, J. D. & Newcomb, P. A., 2014, In : Cancer Epidemiology Biomarkers and Prevention. 23, 8, p. 1700-1704 5 p.

Research output: Contribution to journalArticle

Microsatellite Instability
Colorectal Neoplasms
Confidence Intervals
Registries
Neoplasms
12 Citations (Scopus)

Fibrillar amyloid correlates of preclinical cognitive decline

Stonnington, C. M., Chen, K., Lee, W., Locke, D. E., Dueck, A., Liu, X., Roontiva, A., Fleisher, A. S., Caselli, R. J. & Reiman, E. M., Jan 2014, In : Alzheimer's and Dementia. 10, 1

Research output: Contribution to journalArticle

Apolipoprotein E4
Amyloid
Sex Education
Executive Function
Positron-Emission Tomography
13 Citations (Scopus)

Fracture risk perception study: Patient self-perceptions of bone health often disagree with calculated fracture risk

Grover, M. L., Edwards, F. D., Chang, Y. H. H., Cook, C. B., Behrens, M. C. & Dueck, A., Jan 2014, In : Women's Health Issues. 24, 1

Research output: Contribution to journalArticle

Self Concept
self-image
Bone and Bones
Health
health
35 Citations (Scopus)

Fragile X syndrome due to a missense mutation

Myrick, L. K., Nakamoto-Kinoshita, M., Lindor, N. M., Kirmani, S., Cheng, X. & Warren, S. T., Oct 11 2014, In : European Journal of Human Genetics. 22, 10, p. 1185-1189 5 p.

Research output: Contribution to journalArticle

Fragile X Syndrome
Missense Mutation
Glycine
Glutamic Acid
Mutation
5 Citations (Scopus)
Epidemiology
Hemorrhage
Vulnerable Populations
Anticoagulants
Patient Participation
7 Citations (Scopus)

Genetic variation in prostaglandin synthesis and related pathways, NSAID use and colorectal cancer risk in the colon Cancer Family Registry

Resler, A. J., Makar, K. W., Heath, L., Whitton, J., Potter, J. D., Poole, E. M., Habermann, N., Scherer, D., Duggan, D., Wang, H., Lindor, N. M., Passarelli, M. N., Baron, J. A., Newcomb, P. A., Le Marchand, L. & Ulrich, C. M., 2014, In : Carcinogenesis. 35, 9, p. 2121-2126 6 p., bgu119.

Research output: Contribution to journalArticle

Colonic Neoplasms
Prostaglandins
Registries
Colorectal Neoplasms
Anti-Inflammatory Agents
10 Citations (Scopus)
Incidental Findings
Medical Genetics
Medicine

Global cancer prevention

Okamoto, J. & Leischow, S. J., Jan 1 2014, Fundamentals of Cancer Prevention, Third Edition. Springer Berlin Heidelberg, p. 279-300 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Economic Development
Health
Neoplasms
Human Development
Life Expectancy
27 Citations (Scopus)

Head trauma and in vivo measures of amyloid and neurodegeneration in a population-based study

Mielke, M. M., Savica, R., Wiste, H. J., Weigand, S. D., Vemuri, P. D., Knopman, D. S., Lowe, V., Roberts, R. O., Machulda, M. M., Geda, Y. E., Petersen, R. C. & Jack, C. R. J., Jan 7 2014, In : Neurology. 82, 1, p. 70-76 7 p.

Research output: Contribution to journalArticle

Craniocerebral Trauma
Amyloid
Population
Unconsciousness
Neuroimaging
145 Citations (Scopus)

Higher risk of progression to dementia in mild cognitive impairment cases who revert to normal

Roberts, R. O., Knopman, D. S., Mielke, M. M., Cha, R. H., Pankratz, V. S., Christianson, T. J. H., Geda, Y. E., Boeve, B. F., Ivnik, R. J., Tangalos, E. G., Rocca, W. A. & Petersen, R. C., Jan 28 2014, In : Neurology. 82, 4, p. 317-325 9 p.

Research output: Contribution to journalArticle

Dementia
Cognitive Dysfunction
Mild Cognitive Impairment
Progression
Hazard
26 Citations (Scopus)

High prevalence of mismatch repair deficiency in prostate cancers diagnosed in mismatch repair gene mutation carriers from the colon cancer family registry

Rosty, C., Walsh, M. D., Lindor, N. M., Thibodeau, S. N., Mundt, E., Gallinger, S., Aronson, M., Pollett, A., Baron, J. A., Pearson, S., Clendenning, M., Walters, R. J., Nagler, B. N., Crawford, W. J., Young, J. P., Winship, I., Win, A. K., Hopper, J. L., Jenkins, M. A. & Buchanan, D. D., 2014, In : Familial Cancer. 13, 4, p. 573-582 10 p.

Research output: Contribution to journalArticle

DNA Mismatch Repair
Colonic Neoplasms
Registries
Prostatic Neoplasms
Mutation
13 Citations (Scopus)

How do researchers manage genetic results in practice? The experience of the multinational Colon Cancer Family Registry

Keogh, L. A., Fisher, D., Sheinfeld Gorin, S., Schully, S. D., Lowery, J. T., Ahnen, D. J., Maskiell, J. A., Lindor, N. M., Hopper, J. L., Burnett, T., Holter, S., Arnold, J. L., Gallinger, S., Laurino, M., Esplen, M. J. & Sinicrope, P. S., 2014, In : Journal of Community Genetics. 5, 2, p. 99-108 10 p.

Research output: Contribution to journalArticle

Colonic Neoplasms
Registries
Genetic Research
Research Personnel
Disclosure
30 Citations (Scopus)

Hypothyroidism and risk of mild cognitive impairment in elderly persons a population-based study

Parsaik, A. K., Singh, B., Roberts, R. O., Pankratz, S., Edwards, K. K., Geda, Y. E., Gharib, H., Boeve, B. F., Knopman, D. S. & Petersen, R. C., Feb 2014, In : JAMA Neurology. 71, 2, p. 201-207 7 p.

Research output: Contribution to journalArticle

Hypothyroidism
Population
Dementia
Medical Record Linkage
Apolipoprotein E4
51 Citations (Scopus)

Identification and validation of an anthracycline/cyclophosphamide-based chemotherapy response assay in breast cancer

Mulligan, J. M., Hill, L. A., Deharo, S., Irwin, G., Boyle, D., Keating, K. E., Raji, O. Y., McDyer, F. A., O'Brien, E., Bylesjo, M., Quinn, J. E., Lindor, N. M., Mullan, P. B., James, C. R., Walker, S. M., Kerr, P., James, J., Davison, T. S., Proutski, V., Salto-Tellez, M. & 4 others, Johnston, P. G., Couch, F. J., Paul Harkin, D. & Kennedy, R. D., 2014, In : Journal of the National Cancer Institute. 106, 1, djt335.

Research output: Contribution to journalArticle

Anthracyclines
Cyclophosphamide
Breast Neoplasms
Drug Therapy
DNA Damage
74 Citations (Scopus)

Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis

Whiffin, N., Hosking, F. J., Farrington, S. M., Palles, C., Dobbins, S. E., Zgaga, L., Lloyd, A., Kinnersley, B., Gorman, M., Tenesa, A., Broderick, P., Wang, Y., Barclay, E., Hayward, C., Martin, L., Buchanan, D. D., Win, A. K., Hopper, J., Jenkins, M., Lindor, N. M. & 11 others, Newcomb, P. A., Gallinger, S., Conti, D., Schumacher, F., Casey, G., Liu, T., Campbell, H., Lindblom, A., Houlston, R. S., Tomlinson, I. P. & Dunlop, M. G., 2014, In : Human Molecular Genetics. 23, 17, p. 4729-4737 9 p., ddu177.

Research output: Contribution to journalArticle

Meta-Analysis
Colorectal Neoplasms
Genome
Odds Ratio
Single Nucleotide Polymorphism
9 Citations (Scopus)

Implementation of tobacco cessation quitline practices in the United States and Canada

Saul, J. E., Bonito, J. A., Provan, K., Ruppel, E. & Leischow, S. J., Oct 1 2014, In : American Journal of Public Health. 104, 10, p. e98-e105

Research output: Contribution to journalArticle

Tobacco Use Cessation
Text Messaging
Tobacco
Canada
Surveys and Questionnaires
38 Citations (Scopus)

Implementing individualized medicine into the medical practice

Lazaridis, K. N., MCAllister, T. M., Babovic-Vuksanovic, D., Beck, S. A., Borad, M. J., Bryce, A. H., Chanan Khan, A. A., Ferber, M. J., Fonseca, R., Johnson, K. J., Klee, E. W., Lindor, N. M., MCCormick, J. B., Mc Williams, R. R., Parker, A., Riegert-Johnson, D. L., Rohrer Vitek, C. R., Schahl, K. A., Schultz, C., Stewart, A. K. & 3 others, Then, G. C., Wieben, E. D. & Farrugia, G., 2014, In : American Journal of Medical Genetics, Part C: Seminars in Medical Genetics. 166, 1, p. 15-23 9 p.

Research output: Contribution to journalArticle

Precision Medicine
Medicine
Patient Care
Exome
Workflow
13 Citations (Scopus)

Incidence of dementia among participants and nonparticipants in a longitudinal study of cognitive aging

Knopman, D. S., Roberts, R. O., Pankratz, V. S., Cha, R. H., Rocca, W. A., Mielke, M. M., Boeve, B. F., Tangalos, E. G., Ivnik, R. J., Geda, Y. E. & Petersen, R. C., 2014, In : American Journal of Epidemiology. 180, 4, p. 414-423 10 p.

Research output: Contribution to journalArticle

Longitudinal Studies
Dementia
Incidence
Medical Record Linkage
Sex Education
153 Citations (Scopus)

Integrated Genomic Characterization Reveals Novel, Therapeutically Relevant Drug Targets in FGFR and EGFR Pathways in Sporadic Intrahepatic Cholangiocarcinoma

Borad, M. J., Champion, M. D., Egan, J. B., Liang, W. S., Fonseca, R., Bryce, A. H., McCullough, A. E., Barrett, M., Hunt, K., Patel, M. D., Young, S. W., Collins, J. M., Silva, A. C., Condjella, R. M., Block, M. S., Mc Williams, R. R., Lazaridis, K. N., Klee, E. W., Bible, K. C., Harris, P. & 29 others, Oliver, G. R., Bhavsar, J. D., Nair, A. A., Middha, S., Asmann, Y., Kocher, J-P., Schahl, K., Kipp, B. R., Barr Fritcher, E. G., Baker, A., Aldrich, J., Kurdoglu, A., Izatt, T., Christoforides, A., Cherni, I., Nasser, S., Reiman, R., Phillips, L., McDonald, J., Adkins, J., Mastrian, S. D., Placek, P., Watanabe, A. T., LoBello, J., Han, H., Von Hoff, D., Craig, D. W., Stewart, A. K. & Carpten, J. D., Feb 2014, In : PLoS Genetics. 10, 2, e1004135.

Research output: Contribution to journalArticle

Cholangiocarcinoma
tumor
genomics
drug
inhibitor

Issue Highlights

Abraham, N. S., Feb 2014, In : Clinical Gastroenterology and Hepatology. 12, 2, p. 165-166 2 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
Hereditary Nonpolyposis Colorectal Neoplasms
Penetrance
Genes
Neoplasms
64 Citations (Scopus)

Nicotine blood levels and short-term smoking reduction with an electronic nicotine delivery system

Nides, M. A., Leischow, S. J., Bhatter, M. & Simmons, M., Mar 2014, In : American Journal of Health Behavior. 38, 2, p. 265-274 10 p.

Research output: Contribution to journalArticle

Nicotine
nicotine
smoking
Smoking
electronics
32 Citations (Scopus)

Patient survival after surgical treatment of rectal cancer: Impact of surgeon and hospital characteristics

Etzioni, D. A., Young-Fadok, T. M., Cima, R. R., Wasif, N., Madoff, R. D., Naessens, J. M. & Habermann, E. B., Aug 15 2014, In : Cancer. 120, 16, p. 2472-2481 10 p.

Research output: Contribution to journalArticle

Rectal Neoplasms
Survival
National Cancer Institute (U.S.)
Therapeutics
High-Volume Hospitals
19 Citations (Scopus)

Pleiotropic effects of genetic risk variants for other cancers on colorectal cancer risk: PAGE, GECCO and CCFR consortia

Cheng, I., Kocarnik, J. M., Dumitrescu, L., Lindor, N. M., Chang-Claude, J., Avery, C. L., Caberto, C. P., Love, S. A., Slattery, M. L., Chan, A. T., Baron, J. A., Hindorff, L. A., Park, S. L., Schumacher, F. R., Hoffmeister, M., Kraft, P., Butler, A. M., Duggan, D. J., Hou, L., Carlson, C. S. & 47 others, Monroe, K. R., Lin, Y., Carty, C. L., Mann, S., Ma, J., Giovannucci, E. L., Fuchs, C. S., Newcomb, P. A., Jenkins, M. A., Hopper, J. L., Haile, R. W., Conti, D. V., Campbell, P. T., Potter, J. D., Caan, B. J., Schoen, R. E., Hayes, R. B., Chanock, S. J., Berndt, S. I., Küry, S., Bézieau, S., Ambite, J. L., Kumaraguruparan, G., Richardson, D. M., Goodloe, R. J., Dilks, H. H., Baker, P., Zanke, B. W., Lemire, M., Gallinger, S., Hsu, L., Jiao, S., Harrison, T. A., Seminara, D., Haiman, C. A., Kooperberg, C., Wilkens, L. R., Hutter, C. M., White, E., Crawford, D. C., Heiss, G., Hudson, T. J., Brenner, H., Bush, W. S., Casey, G., Le Marchand, L. & Peters, U., May 1 2014, In : Gut. 63, 5, p. 800-807 8 p.

Research output: Contribution to journalArticle

Molecular Epidemiology
Genomics
Colonic Neoplasms
Registries
Colorectal Neoplasms
41 Citations (Scopus)

Portrayal of electronic cigarettes on YouTube

Luo, C., Zheng, X., Zeng, D. D. & Leischow, S., Oct 3 2014, In : BMC Public Health. 14, 1, 1028.

Research output: Contribution to journalArticle

Tobacco Products
Smoking
Electronic Cigarettes
Health Promotion
Canada
21 Citations (Scopus)

Public perceptions of presymptomatic testing for Alzheimer disease

Caselli, R. J., Langbaum, J., Marchant, G. E., Lindor, R. A., Hunt, K. S., Henslin, B. R., Dueck, A. & Robert, J. S., Oct 1 2014, In : Mayo Clinic Proceedings. 89, 10, p. 1389-1396 8 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Biomarkers
Registries
Research
Psychology
104 Citations (Scopus)

Recommended patient-reported core set of symptoms to measure in adult cancer treatment trials

Reeve, B. B., Mitchell, S. A., Dueck, A., Basch, E., Cella, D., Reilly, C. M., Minasian, L. M., Denicoff, A. M., O'Mara, A. M., Fisch, M. J., Chauhan, C., Aaronson, N. K., Coens, C. & Bruner, D. W., Jul 9 2014, In : Journal of the National Cancer Institute. 106, 7, dju129.

Research output: Contribution to journalArticle

Clinical Trials
Neoplasms
Consensus
Quality of Life
Patient Advocacy
40 Citations (Scopus)

Refined histopathological predictors of BRCA1 and BRCA2 mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia

ABCTB Investigators, EMBRACE Group, GENICA-Network, HEBON Group & KConFab investigators, 2014, In : Breast cancer research : BCR. 16, 6, p. 3419 1 p.

Research output: Contribution to journalArticle

Research Personnel
Breast Neoplasms
Mutation
Estrogen Receptors
Women's Rights
66 Citations (Scopus)

Risk of colorectal cancer for carriers of mutations in MUTYH, with and without a family history of cancer

Win, A. K., Dowty, J. G., Cleary, S. P., Kim, H., Buchanan, D. D., Young, J. P., Clendenning, M., Rosty, C., Macinnis, R. J., Giles, G. G., Boussioutas, A., Macrae, F. A., Parry, S., Goldblatt, J., Baron, J. A., Burnett, T., Le Marchand, L., Newcomb, P. A., Haile, R. W., Hopper, J. L. & 6 others, Cotterchio, M., Gallinger, S., Lindor, N. M., Tucker, K. M., Winship, I. M. & Jenkins, M. A., 2014, In : Gastroenterology. 146, 5

Research output: Contribution to journalArticle

Colorectal Neoplasms
Mutation
Neoplasms
Confidence Intervals
Population
38 Citations (Scopus)

The neuropsychology of normal aging and preclinical Alzheimer's disease

Caselli, R. J., Locke, D. E., Dueck, A., Knopman, D. S., Woodruff, B. K., Hoffman-Snyder, C., Rademakers, R. V., Fleisher, A. S. & Reiman, E. M., Jan 2014, In : Alzheimer's and Dementia. 10, 1, p. 84-92 9 p.

Research output: Contribution to journalArticle

Apolipoprotein E4
Neuropsychology
Alzheimer Disease
National Institute on Aging (U.S.)
Homozygote
44 Citations (Scopus)

Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A

Wang, H., Burnett, T., Kono, S., Haiman, C. A., Iwasaki, M., Wilkens, L. R., Loo, L. W. M., Van Den Berg, D., Kolonel, L. N., Henderson, B. E., Keku, T. O., Sandler, R. S., Signorello, L. B., Blot, W. J., Newcomb, P. A., Pande, M., Amos, C. I., West, D. W., Bézieau, S., Berndt, S. I. & 15 others, Zanke, B. W., Hsu, L., Lindor, N. M., Haile, R. W., Hopper, J. L., Jenkins, M. A., Gallinger, S., Casey, G., Stenzel, S. L., Schumacher, F. R., Peters, U., Gruber, S. B., Tsugane, S., Stram, D. O. & Le Marchand, L., Aug 8 2014, In : Nature Communications. 5, 4613.

Research output: Contribution to journalArticle

genome
Genome-Wide Association Study
loci
Colorectal Neoplasms
Genes
11 Citations (Scopus)

Transoral laser microsurgery followed by radiation therapy for oropharyngeal tumors: The mayo clinic arizona experience

Patel, S. H., Hinni, M. L., Hayden, R. E., Wong, W. W., Dueck, A., Zarka, M. A., Curtis, K. K. & Halyard, M. Y., Feb 2014, In : Head and Neck. 36, 2, p. 220-225 6 p.

Research output: Contribution to journalArticle

Microsurgery
Lasers
Radiotherapy
Oropharyngeal Neoplasms
Confidence Intervals
2013
52 Citations (Scopus)

A classification model for BRCA2 DNA binding domain missense variants based on homology-directed repair activity

Guidugli, L., Pankratz, V. S., Singh, N., Thompson, J., Erding, C. A., Engel, C., Schmutzler, R., Domchek, S., Nathanson, K., Radice, P., Singer, C., Tonin, P. N., Lindor, N. M., Goldgar, D. E. & Couch, F. J., Jan 1 2013, In : Cancer Research. 73, 1, p. 265-275 11 p.

Research output: Contribution to journalArticle

DNA Breaks
DNA Repair
DNA
Virulence
Missense Mutation
96 Citations (Scopus)

A literature synthesis of symptom prevalence and severity in persons receiving active cancer treatment

Reilly, C. M., Bruner, D. W., Mitchell, S. A., Minasian, L. M., Basch, E., Dueck, A., Cella, D. & Reeve, B. B., Jun 2013, In : Supportive Care in Cancer. 21, 6, p. 1525-1550 26 p.

Research output: Contribution to journalArticle

Neoplasms
Therapeutics
Cancer Care Facilities
Equipment and Supplies
Aptitude
54 Citations (Scopus)

A Multifactorial Likelihood Model for MMR Gene Variant Classification Incorporating Probabilities Based on Sequence Bioinformatics and Tumor Characteristics: A Report from the Colon Cancer Family Registry

Thompson, B. A., Goldgar, D. E., Paterson, C., Clendenning, M., Walters, R., Arnold, S., Parsons, M. T., Michael, W. D., Gallinger, S., Haile, R. W., Hopper, J. L., Jenkins, M. A., Lemarchand, L., Lindor, N. M., Newcomb, P. A., Thibodeau, S. N., Young, J. P., Buchanan, D. D., Tavtigian, S. V. & Spurdle, A. B., Jan 2013, In : Human Mutation. 34, 1, p. 200-209 10 p.

Research output: Contribution to journalArticle

DNA Mismatch Repair
Computational Biology
Colonic Neoplasms
Virulence
Registries
4 Citations (Scopus)

An empirical analysis of social interaction on tobacco-oriented social networks

Liang, Y., Zheng, X., Zeng, D. D., Zhou, X. & Leischow, S., 2013, Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). Vol. 8040 LNCS. p. 18-23 6 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 8040 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Tobacco
Social Interaction
Empirical Analysis
Social Networks
Fans
19 Citations (Scopus)

Are the common genetic variants associated with colorectal cancer risk for DNA mismatch repair gene mutation carriers?

Win, A. K., Hopper, J. L., Buchanan, D. D., Young, J. P., Tenesa, A., Dowty, J. G., Giles, G. G., Goldblatt, J., Winship, I., Boussioutas, A., Young, G. P., Parry, S., Baron, J. A., Duggan, D., Gallinger, S., Newcomb, P. A., Haile, R. W., Marchand, L. L., Lindor, N. M. & Jenkins, M. A., May 2013, In : European Journal of Cancer. 49, 7, p. 1578-1587 10 p.

Research output: Contribution to journalArticle

DNA Mismatch Repair
Colorectal Neoplasms
Mutation
Genes
Alleles
165 Citations (Scopus)
Gait
Cognition
Executive Function
Cognitive Dysfunction
Walking Speed
49 Citations (Scopus)

BRCA1/2 sequence variants of uncertain significance: A primer for providers to assist in discussions and in medical management

Lindor, N. M., Goldgar, D. E., Tavtigian, S. V., Plon, S. E. & Couch, F. J., May 2013, In : Oncologist. 18, 5, p. 518-524 7 p.

Research output: Contribution to journalArticle

International Agencies
Genetic Testing
BRCA2 Gene
BRCA1 Gene
Neoplasms
21 Citations (Scopus)

Caloric intake, aging, and mild cognitive impairment: A population-based study

Geda, Y. E., Ragossnig, M., Roberts, L. A., Roberts, R. O., Pankratz, V. S., Christianson, T. J. H., Mielke, M. M., Levine, J. A., Boeve, B. F., Sochor, O., Tangalos, E. G., Knopman, D. S. & Petersen, R. C., 2013, In : Journal of Alzheimer's Disease. 34, 2, p. 501-507 7 p.

Research output: Contribution to journalArticle

Energy Intake
Population
Odds Ratio
Confidence Intervals
Apolipoprotein E4
105 Citations (Scopus)

Cancer Risks for MLH1 and MSH2 Mutation Carriers

Dowty, J. G., Win, A. K., Buchanan, D. D., Lindor, N. M., Macrae, F. A., Clendenning, M., Antill, Y. C., Thibodeau, S. N., Casey, G., Gallinger, S., Marchand, L. L., Newcomb, P. A., Haile, R. W., Young, G. P., James, P. A., Giles, G. G., Gunawardena, S. R., Leggett, B. A., Gattas, M., Boussioutas, A. & 7 others, Ahnen, D. J., Baron, J. A., Parry, S., Goldblatt, J., Young, J. P., Hopper, J. L. & Jenkins, M. A., Mar 2013, In : Human Mutation. 34, 3, p. 490-497 8 p.

Research output: Contribution to journalArticle

Mutation
Neoplasms
Colorectal Neoplasms
Endometrial Neoplasms
Colonic Neoplasms
41 Citations (Scopus)

Cardiac disease associated with increased risk of nonamnestic cognitive impairment

Roberts, R. O., Geda, Y. E., Knopman, D. S., Cha, R. H., Pankratz, V. S., Boeve, B. F., Tangalos, E. G., Ivnik, R. J., Mielke, M. M. & Petersen, R. C., Mar 2013, In : JAMA Neurology. 70, 3, p. 374-382 9 p.

Research output: Contribution to journalArticle

Heart Diseases
Dementia
Vascular Dementia
Cognitive Dysfunction
Cognitive Impairment
37 Citations (Scopus)

Chronic obstructive pulmonary disease and association with mild cognitive impairment: The Mayo Clinic Study of Aging

Singh, B., Parsaik, A. K., Mielke, M. M., Roberts, R. O., Scanlon, P. D., Geda, Y. E., Pankratz, V. S., Christianson, T., Yawn, B. P. & Petersen, R. C., 2013, In : Mayo Clinic Proceedings. 88, 11, p. 1222-1230 9 p.

Research output: Contribution to journalArticle

Chronic Obstructive Pulmonary Disease
Odds Ratio
Cognitive Dysfunction
Logistic Models
Population
37 Citations (Scopus)

Colon and rectal cancer survival by tumor location and microsatellite instability: The colon cancer family registry

Phipps, A. I., Lindor, N. M., Jenkins, M. A., Baron, J. A., Win, A. K., Gallinger, S., Gryfe, R. & Newcomb, P. A., Aug 2013, In : Diseases of the Colon and Rectum. 56, 8, p. 937-944 8 p.

Research output: Contribution to journalArticle

Microsatellite Instability
Rectal Neoplasms
Colonic Neoplasms
Registries
Survival
36 Citations (Scopus)

Comparison of the clinical prediction model PREMM1,2,6 and molecular testing for the systematic identification of Lynch syndrome in colorectal cancer

Kastrinos, F., Steyerberg, E. W., Balmaña, J., Mercado, R., Gallinger, S., Haile, R., Casey, G., Hopper, J. L., LeMarchand, L., Lindor, N. M., Newcomb, P. A., Thibodeau, S. N. & Syngal, S., Feb 2013, In : Gut. 62, 2, p. 272-279 8 p.

Research output: Contribution to journalArticle

Hereditary Nonpolyposis Colorectal Neoplasms
Microsatellite Instability
Colorectal Neoplasms
Immunohistochemistry
DNA Mismatch Repair
14 Citations (Scopus)

Deciphering the genetic architecture of low-penetrance susceptibility to colorectal cancer

Whiffin, N., Dobbins, S. E., Hosking, F. J., Palles, C., Tenesa, A., Wang, Y., Farrington, S. M., Jones, A. M., Broderick, P., Campbell, H., Newcomb, P. A., Casey, G., Conti, D. V., Schumacher, F., Gallinger, S., Lindor, N. M., Hopper, J., Jenkins, M., Dunlop, M. G., Tomlinson, I. P. & 1 others, Houlston, R. S., Dec 2013, In : Human Molecular Genetics. 22, 24, p. 5075-5082 8 p., ddt357.

Research output: Contribution to journalArticle

Penetrance
Colorectal Neoplasms
Genome-Wide Association Study
Linkage Disequilibrium
Meta-Analysis